LOCUS       DAVBNN010000001        72427 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBNN010000001 DAVBNN010000000
VERSION     DAVBNN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72427
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.001"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(842..1000)
                     /locus_tag="VQ847_000001"
     CDS             complement(842..1000)
                     /locus_tag="VQ847_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049425.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(1010..2320)
                     /gene="obgE"
                     /locus_tag="VQ847_000002"
     CDS             complement(1010..2320)
                     /gene="obgE"
                     /locus_tag="VQ847_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3049426.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(2384..2518)
                     /locus_tag="VQ847_000003"
     CDS             complement(2384..2518)
                     /locus_tag="VQ847_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3049427.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(2577..2753)
                     /locus_tag="VQ847_000004"
     CDS             complement(2577..2753)
                     /locus_tag="VQ847_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3049428.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(2784..4109)
                     /locus_tag="VQ847_000005"
     CDS             complement(2784..4109)
                     /locus_tag="VQ847_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3049429.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(4125..5168)
                     /gene="cpoA"
                     /locus_tag="VQ847_000006"
     CDS             complement(4125..5168)
                     /gene="cpoA"
                     /locus_tag="VQ847_000006"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3049430.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(5283..5612)
                     /locus_tag="VQ847_000007"
     CDS             complement(5283..5612)
                     /locus_tag="VQ847_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3049431.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(5626..6735)
                     /gene="rpoD"
                     /locus_tag="VQ847_000008"
     CDS             complement(5626..6735)
                     /gene="rpoD"
                     /locus_tag="VQ847_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3049432.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(6738..8498)
                     /gene="dnaG"
                     /locus_tag="VQ847_000009"
     CDS             complement(6738..8498)
                     /gene="dnaG"
                     /locus_tag="VQ847_000009"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3049433.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(8588..9346)
                     /locus_tag="VQ847_000010"
     CDS             complement(8588..9346)
                     /locus_tag="VQ847_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049434.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(9343..10209)
                     /locus_tag="VQ847_000011"
     CDS             complement(9343..10209)
                     /locus_tag="VQ847_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3049435.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(10278..11282)
                     /locus_tag="VQ847_000012"
     CDS             complement(10278..11282)
                     /locus_tag="VQ847_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3049436.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(11395..11612)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(11695..14391)
                     /gene="ppc"
                     /locus_tag="VQ847_000013"
     CDS             complement(11695..14391)
                     /gene="ppc"
                     /locus_tag="VQ847_000013"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3049437.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(14411..15640)
                     /locus_tag="VQ847_000014"
     CDS             complement(14411..15640)
                     /locus_tag="VQ847_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3049438.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(15796..16098)
                     /locus_tag="VQ847_000015"
                     /pseudo
     CDS             complement(15796..16098)
                     /locus_tag="VQ847_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16546..16767)
                     /locus_tag="VQ847_000016"
     CDS             complement(16546..16767)
                     /locus_tag="VQ847_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3049439.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(17447..18658)
                     /locus_tag="VQ847_000017"
                     /pseudo
     CDS             complement(17447..18658)
                     /locus_tag="VQ847_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(18660..19904)
                     /locus_tag="VQ847_000018"
     CDS             complement(18660..19904)
                     /locus_tag="VQ847_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3049440.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(19934..20962)
                     /gene="galE"
                     /locus_tag="VQ847_000019"
     CDS             complement(19934..20962)
                     /gene="galE"
                     /locus_tag="VQ847_000019"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3049441.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            complement(20964..21635)
                     /locus_tag="VQ847_000020"
     CDS             complement(20964..21635)
                     /locus_tag="VQ847_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049442.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            complement(21638..22732)
                     /locus_tag="VQ847_000021"
     CDS             complement(21638..22732)
                     /locus_tag="VQ847_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049443.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            complement(22736..23266)
                     /locus_tag="VQ847_000022"
     CDS             complement(22736..23266)
                     /locus_tag="VQ847_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049444.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            complement(23263..23985)
                     /locus_tag="VQ847_000023"
     CDS             complement(23263..23985)
                     /locus_tag="VQ847_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3049445.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            complement(23972..24841)
                     /locus_tag="VQ847_000024"
     CDS             complement(23972..24841)
                     /locus_tag="VQ847_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3049446.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            complement(24945..25016)
                     /locus_tag="VQ847_000025"
     CDS             complement(24945..25016)
                     /locus_tag="VQ847_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3049447.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            25098..25950
                     /locus_tag="VQ847_000026"
                     /pseudo
     CDS             25098..25950
                     /locus_tag="VQ847_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(25995..27859)
                     /locus_tag="VQ847_000027"
                     /pseudo
     CDS             complement(25995..27859)
                     /locus_tag="VQ847_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(27846..28144)
                     /locus_tag="VQ847_000028"
                     /pseudo
     CDS             complement(27846..28144)
                     /locus_tag="VQ847_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            complement(28220..28579)
                     /locus_tag="VQ847_000029"
     CDS             complement(28220..28579)
                     /locus_tag="VQ847_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049448.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            complement(29398..30555)
                     /locus_tag="VQ847_000030"
     CDS             complement(29398..30555)
                     /locus_tag="VQ847_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049449.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(30583..31344)
                     /locus_tag="VQ847_000031"
     CDS             complement(30583..31344)
                     /locus_tag="VQ847_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3049450.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            complement(31344..31820)
                     /locus_tag="VQ847_000032"
     CDS             complement(31344..31820)
                     /locus_tag="VQ847_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3049451.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(32265..32720)
                     /locus_tag="VQ847_000033"
     CDS             complement(32265..32720)
                     /locus_tag="VQ847_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049452.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(32995..34732)
                     /locus_tag="VQ847_000034"
                     /pseudo
     CDS             complement(32995..34732)
                     /locus_tag="VQ847_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(34895..35779)
                     /locus_tag="VQ847_000035"
     CDS             complement(34895..35779)
                     /locus_tag="VQ847_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3049453.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(35891..36745)
                     /locus_tag="VQ847_000036"
     CDS             complement(35891..36745)
                     /locus_tag="VQ847_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3049454.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(36803..37561)
                     /locus_tag="VQ847_000037"
     CDS             complement(36803..37561)
                     /locus_tag="VQ847_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3049455.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(37623..37811)
                     /locus_tag="VQ847_000038"
     CDS             complement(37623..37811)
                     /locus_tag="VQ847_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3049456.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(38134..38700)
                     /locus_tag="VQ847_000039"
     CDS             complement(38134..38700)
                     /locus_tag="VQ847_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049457.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(38968..40647)
                     /locus_tag="VQ847_000040"
                     /pseudo
     CDS             complement(38968..40647)
                     /locus_tag="VQ847_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(40739..40900)
                     /locus_tag="VQ847_000041"
     CDS             complement(40739..40900)
                     /locus_tag="VQ847_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049458.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(41584..41898)
                     /locus_tag="VQ847_000042"
     CDS             complement(41584..41898)
                     /locus_tag="VQ847_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049459.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(41864..42253)
                     /locus_tag="VQ847_000043"
     CDS             complement(41864..42253)
                     /locus_tag="VQ847_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3049460.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(42641..43435)
                     /locus_tag="VQ847_000044"
     CDS             complement(42641..43435)
                     /locus_tag="VQ847_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049461.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(43435..44442)
                     /locus_tag="VQ847_000045"
     CDS             complement(43435..44442)
                     /locus_tag="VQ847_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3049462.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(44442..45449)
                     /locus_tag="VQ847_000046"
     CDS             complement(44442..45449)
                     /locus_tag="VQ847_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3049463.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(45439..46464)
                     /locus_tag="VQ847_000047"
     CDS             complement(45439..46464)
                     /locus_tag="VQ847_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3049464.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(46857..47075)
                     /locus_tag="VQ847_000048"
     CDS             complement(46857..47075)
                     /locus_tag="VQ847_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3049465.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(47321..47599)
                     /locus_tag="VQ847_000049"
     CDS             complement(47321..47599)
                     /locus_tag="VQ847_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049466.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(47813..49444)
                     /gene="rlmD"
                     /locus_tag="VQ847_000050"
     CDS             complement(47813..49444)
                     /gene="rlmD"
                     /locus_tag="VQ847_000050"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3049467.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(49518..50492)
                     /locus_tag="VQ847_000051"
     CDS             complement(49518..50492)
                     /locus_tag="VQ847_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3049468.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(50566..51180)
                     /gene="pmp23"
                     /locus_tag="VQ847_000052"
     CDS             complement(50566..51180)
                     /gene="pmp23"
                     /locus_tag="VQ847_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3049469.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(51180..52154)
                     /locus_tag="VQ847_000053"
     CDS             complement(51180..52154)
                     /locus_tag="VQ847_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3049470.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(52162..53418)
                     /locus_tag="VQ847_000054"
     CDS             complement(52162..53418)
                     /locus_tag="VQ847_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3049471.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(53480..53911)
                     /locus_tag="VQ847_000055"
     CDS             complement(53480..53911)
                     /locus_tag="VQ847_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3049472.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(53913..54512)
                     /locus_tag="VQ847_000056"
     CDS             complement(53913..54512)
                     /locus_tag="VQ847_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3049473.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(54499..55338)
                     /gene="prmC"
                     /locus_tag="VQ847_000057"
     CDS             complement(54499..55338)
                     /gene="prmC"
                     /locus_tag="VQ847_000057"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3049474.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(55338..56417)
                     /gene="prfA"
                     /locus_tag="VQ847_000058"
     CDS             complement(55338..56417)
                     /gene="prfA"
                     /locus_tag="VQ847_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3049475.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(56427..56906)
                     /locus_tag="VQ847_000059"
     CDS             complement(56427..56906)
                     /locus_tag="VQ847_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3049476.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(56896..57495)
                     /locus_tag="VQ847_000060"
     CDS             complement(56896..57495)
                     /locus_tag="VQ847_000060"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3049477.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            57618..57800
                     /locus_tag="VQ847_000061"
     CDS             57618..57800
                     /locus_tag="VQ847_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3049478.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            57937..59310
                     /gene="mnmE"
                     /locus_tag="VQ847_000062"
     CDS             57937..59310
                     /gene="mnmE"
                     /locus_tag="VQ847_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3049479.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(59357..60292)
                     /gene="dapA"
                     /locus_tag="VQ847_000063"
     CDS             complement(59357..60292)
                     /gene="dapA"
                     /locus_tag="VQ847_000063"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3049480.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(60348..61424)
                     /locus_tag="VQ847_000064"
     CDS             complement(60348..61424)
                     /locus_tag="VQ847_000064"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3049481.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(61766..61838)
                     /locus_tag="VQ847_000065"
     tRNA            complement(61766..61838)
                     /locus_tag="VQ847_000065"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61803..61805),aa:Thr,seq:ggt)
     gene            complement(61938..62447)
                     /locus_tag="VQ847_000066"
     CDS             complement(61938..62447)
                     /locus_tag="VQ847_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3049482.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(62445..62541)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            62570..63001
                     /locus_tag="VQ847_000067"
     CDS             62570..63001
                     /locus_tag="VQ847_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3049483.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            63083..63460
                     /gene="mscL"
                     /locus_tag="VQ847_000068"
     CDS             63083..63460
                     /gene="mscL"
                     /locus_tag="VQ847_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3049484.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(63502..64596)
                     /gene="hemH"
                     /locus_tag="VQ847_000069"
     CDS             complement(63502..64596)
                     /gene="hemH"
                     /locus_tag="VQ847_000069"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET3049485.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVTLVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRSPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            64751..65974
                     /gene="pepT"
                     /locus_tag="VQ847_000070"
     CDS             64751..65974
                     /gene="pepT"
                     /locus_tag="VQ847_000070"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3049486.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(66010..66639)
                     /locus_tag="VQ847_000071"
     CDS             complement(66010..66639)
                     /locus_tag="VQ847_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049487.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            66604..66825
                     /locus_tag="VQ847_000072"
     CDS             66604..66825
                     /locus_tag="VQ847_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049488.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(67096..68107)
                     /locus_tag="VQ847_000073"
                     /pseudo
     CDS             complement(67096..68107)
                     /locus_tag="VQ847_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(68333..71452)
                     /gene="phtE"
                     /locus_tag="VQ847_000074"
     CDS             complement(68333..71452)
                     /gene="phtE"
                     /locus_tag="VQ847_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3049489.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(71663..>72427)
                     /gene="phtD"
                     /locus_tag="VQ847_000075"
     CDS             complement(71663..>72427)
                     /gene="phtD"
                     /locus_tag="VQ847_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET3049490.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRVPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT        21816 a        14637 c        11546 g        24428 t
ORIGIN      
        1 gatggaactg acgtagtcag tatcctacac gtacggcaag gcgatattga cgtgatttga
       61 agagattttc gaagagtata atctttctcg aatcgctatt gccccttttt tatcccctga
      121 aaccgagtag gagctaagac tagatctctt atctaagtat cggaatacgg ctgttcaact
      181 aaattttagc aagaacttct cccccttctc tcagttcaca gaagcgtttt atacataccg
      241 tcctatcaga caatctattt taaagataac cgtgactcag gatcacttct atctgtcgtt
      301 ttctctttat agtgatagac ctcacgggat aagtcgtaca tctttcctcg tgtatacaag
      361 atataaggac gttaaaaggt tacagtgaaa atagaaaatc ttagtacgaa ttcaattact
      421 ctcgtgattt acgcatatag gttacgacta cctttttgga ctttagagtt tgaggccctc
      481 ttatccgcta tatacgcctt attatcacgt tcctgttcgt agagccacga tttcgctatc
      541 ccttcttctg acaattctta tttccagcgt cagacttaaa acggtctatc cccagaccat
      601 tttaatccgc tacctcacga tagtcaggct tgggaatcgc tatttgactc gccgagaact
      661 ttgacatcag atatactata acaaattgaa ataagaatca aacaatttaa ttttgaaatt
      721 caaatcaatt tataacaata ttttagaaga tatgctgtgc tattccagat tcagtttgct
      781 atacatgcct gtcgtaccac aaaatcccgt gtctgatgag gcacgggatt ttttagcttc
      841 tttactgaga tggattttcc tttttagttc gtgccaatct caaggcacga tttggattga
      901 gacgattaaa tagttcttcc aatttctttt cattccaaac gtctgcggcg gaaacaaaat
      961 taccatccgc atctcggaaa gatatcggtt tatctcccat accagtctcc tagtctacaa
     1021 attcaaactc aaatttacca atgcggacca aatccccatc tttagctcca cgcgcacgaa
     1081 gggcttcatc aacccccata ccacgaagct gacgggcaaa tttcatgaca gattcatcac
     1141 gatcaaagtt ggtcatatta aagagtttca tgagtttttc accagaaagt acccatgtcg
     1201 catcgtcatc acgactaatt tcaaaggctt tttcttcttc gtcaaatcca tagtaagttt
     1261 cttcttccat atcggactcg tcgtagagca aaaattctgg tgtcttgtct aacaattcag
     1321 ctgtagcatc taaaagtgtt gccagacctt gcttggtcaa tccagaaatt gggaagatag
     1381 ctggtaactc ttcaaattca tcataatttt cagccaattt tttcttaaat tcttcaagat
     1441 tttcctgact ctcaggcatg tccatcttat tagctacaat aatctgtgga cgctccatga
     1501 ggcgaagatt gtaagactcc agctctttat tgatagctaa gtaatcctca tatggatcac
     1561 ggccttcgct agctgacata tcaatgatgt gaaggataac acgtgtacgc tcgatgtgac
     1621 ggaggaactg agttcccaaa ccaacacctt gactagcccc ttcaatcaaa cctggcaagt
     1681 cggctactgc aaaggattca cctgattggg tgcgaaccat acctaaattt ggtacaatag
     1741 tggtaaagtg gtaggcacca attttaggct tagctgaggt aataacactt aaaagtgttg
     1801 acttccctac agatgggaat cctactaaac cgacatctgc caagattttt agttccaatt
     1861 gtaactcacg ttcctgacct ggttctccat tttcagagat ttccggtgca ggattttttg
     1921 gtgtcgcgaa acgaatattt ccacgtccac cacgaccacc gtgggcaacg ataaattctt
     1981 gcccatgttc aatcaaatct gttaaaacct tgccagtctc cgcatcacga acagtcgtac
     2041 cttgtggtac tcgaactcta aggtcctcag caccacgacc atgcatccct ttggtcatcc
     2101 ctttttcacc agaatcagcc ttgaaatgac gattgtagcg aaaatccatc aaggtacgta
     2161 gtccttcgtc tacaacgaag accacattgc ctccacgacc accatcacca ccccaagggc
     2221 ctccattagg gacatatttt tcacgacgaa aggcaaccat accatcgcca ccattaccag
     2281 ccttgacctt aatcttagct gtatctaaaa acatactcat tatttcttct cactttaaaa
     2341 aagggctggg aaatcccagt cactaaattt tcttgaatct attttataga ttactgaggg
     2401 caccaattgc agttgcaaaa attcccaata aacttgctac tagcatgata atcacgataa
     2461 acaaggttat tttctcaaac atagtttttt tacgatttcc attatctcca aatgccattt
     2521 ttctctcctt cgttacattc tattttctat tatcttagca tgaattgagc tagttttcaa
     2581 tagtcagttg ctactggtgc gataatccat aaaataatgt aagctacaat tccagctccg
     2641 taacagcaag taagaacacc ccaaatgact tgaacgatag tcggatccat atccagataa
     2701 tgggccaccc cagcacaaac acccgcaatc tttttatcac gaccgcttct cattaattgt
     2761 ttttttcata gctgttcctc tttctattct tcatggtctt tccaatagtc tctcatactg
     2821 atcaactgtg tttttgaagc cttcaacatg cgtctagatc cttttacagg tacagcaacc
     2881 acctgttgcg gaagatacaa aactgtctta aagatacgct gactgaccgt atcatcttta
     2941 gccaaatctt tctggaagtt atttgaaata atggcatcca gataaaactc atgcactcgt
     3001 ttcccaaagt tctcagctga aatctcatac aatttctctg ataaggtatg ctcattcatg
     3061 tctggtgttg caatcagggc ttccgaaata gcaccagcca aatcatgttc tccatagtac
     3121 aaggttccaa acattttatc actgatgagg ttgttcaaat aaggatttcc gtgagcaatg
     3181 acaggtgttc cactggctaa gctttccaag taggtcaaac cttgcgtttc gcttgtcgat
     3241 gccgaaatga agaaatccgc cgctttatag taaagagccg tctcactagg agcaatcatc
     3301 cctgtaaaga tgactgagtc ttgaatctct aggttctggg cttgctcttt gaggtcattc
     3361 agataagggc catccccagc tactaccagt ttaaccttgt cttcctcttt cagaacatca
     3421 gcaaaggcta ctaaaactgc ttgaatattt ttttcatagg agattctcga aagactaagc
     3481 aacgtctttt caccatcttg aatccctagt ttactacgca gttctttcaa attttcctgc
     3541 ttgatttccg gacgctcaaa cttggctaat tcaattccag taggaatgac ccgtttttca
     3601 accttgacct tataatcaga tagcaagtca cggacaatct cactagggca aataacccca
     3661 tccacatcat gcaggaaacc tctaaccaga tacttgacca tactcggccg gatcaacatc
     3721 cccttagcaa tataatggac atagtcttca tactgggtgt gataggtatg gatgactgga
     3781 attttcaatt cacgcgcaat ccaaatcccc aacaggccaa gagaaaattc tgtctgagta
     3841 tggataatat ctagctgata ctgtttagca atttcaagtg ccttgctaaa acctcggtag
     3901 gcaaagcgac gatccttaaa agcaaagaaa ggaacacttg gaatgcggat aatttgccaa
     3961 tcttcgtagc gattgacatc cttatctgtc gtcgtaaaga taaaaacagc atgtccctgc
     4021 ttttcaagtt ctgttttcaa ggttcgaata ctggtcgcaa caccagaaac ctgaggaaaa
     4081 taggtatctg taaataaacc aattcgcata gattacctca ctttttactt tctccctaaa
     4141 gcggcttgtt tctcataaaa gtccaaccag atttgtaaca gatgctcttc agaatactct
     4201 ctggaaatat tcttagcctt ttctttgaga tcttttaagg tagcaggatt tgcttgatat
     4261 tccaaaatag cctctttcat ctcttctcta cccgctgtcg cccgataatt tccctccaaa
     4321 atcaccttat agagatctaa atcacgcaac ataataggag cctcacaact cgcagcttct
     4381 aaaatagtca taggaaagag ctcattgtaa ctaggcaaca agaaaagatc cgctagagca
     4441 tacaattcgc gcatccgctc tggcgataca atgcctggaa aaatcaaatt tttaggggga
     4501 ttttccataa ttttcttata gtgttcataa ccatctgtca taccaccaaa agagaagcca
     4561 ccagcccaga taaaggtaat ctgaggcaat tcctcagcca gacggataaa gtcatcaatc
     4621 cctttacgtt tctgaacttg cccagcacct actacgataa actgattgtc actaagacca
     4681 agatctgtgc gcagtctaac tacctcttct tgtggtagag gatgccattt ttccttgttg
     4741 acaaagttag gaatataggt cactttttca cgtggaatac cagctgctac caaatcctca
     4801 ataaacatag gattgaccac aaccaagtgc tccatccggt tgtaaaaaga aaatacatag
     4861 cgtttcacaa ttccctttaa gaaaaatgga attttcaaac ttccctcaag tgtagctggc
     4921 aagaaatgca catagccaat ctttctccct gagcgtttct tttggaaggt tgataaataa
     4981 tagggaaaat caatcgtatg aaagtgagtc acatctgcct cgattggaag attttctgta
     5041 acaatcaatt ggtccttggc agcacggtga agaagacgaa ctaattcacg gtaagcacct
     5101 gaaactccct gtcctgctac tttctcactt gaactcaaca tattgatgcg taatttcttt
     5161 ttctccataa ctactattat atcattttct ttgaataaaa tcagcaaaag aaaggagaga
     5221 ctagaggaaa agaggggaaa tttcctcgct tttccaacag tctctcacat gcttttatat
     5281 gtttacttaa tgcctagggc aatgcgggca tagcgactca ttttttcaac tgtccaggct
     5341 ggataccaga ctaatttaac ctcagtatcc gttacttctg gaacctctat catagcatca
     5401 taaatctggt ctgtcaaaag gtctgctaag ggacaaccca tagttgtcaa agtcatgtca
     5461 atctctgttt gccctgtgtc accgtcaaaa cgaatctcat agatcaaacc aagattgaca
     5521 atatcgattc ccaactcagg gtcgatgact tcttccaagg ctgttaaaat ccgtgttttg
     5581 atgttttcaa tttgctcttc tgtataagcc atattttcct cactcttagt cttcaataaa
     5641 atcacgaagc ggtttgctac gacttggttg gcgtagtttt ctcaaagcct ttgcttcaat
     5701 ctgacggata cgctcacgag ttacgttaaa gactttcccc acatcttcaa gtgtgcgcat
     5761 ttttccatca tctagtccaa aacgtagacg cagaacattt tcttcacggt ctgtaagagt
     5821 atctaagatt tcatccaatt gctcacgcaa gacgatacga gtcgtataat ccactggatt
     5881 ttcaatcact tcatcttcga taaagtctcc gaggtggcta tcgtcctctt caccgatagg
     5941 agtttcaaga gatactggtt cttgggcaat cttcaagatt tcacgaacct tatcaggtgt
     6001 catatccatt cgttcagcaa tctgttctgg tgtcggatct tgccccaatt cttgaaggag
     6061 attccgctgt tcacgaacca atttattgat agtttcaacc atgtgaactg ggatacggat
     6121 ggtacgagct tggtccgcaa tagcacgagt gatagcctga cgaatccacc aagttgcata
     6181 agttgaaaac ttgaaccctt tagaatagtc aaacttgtca accgccttca tcaagcccat
     6241 atttccttct tgaatcaagt caaggaactg cataccacga ccgacatagc gtttggcaat
     6301 ggaaacaacc aaacgaagat tggcttccgc aagacgttgt ttggcttcga tatcaccagc
     6361 ttcaacagcc agtgccaact ctttctcctc ttcattggtc aagagaggaa cgacccctat
     6421 ttctttcaag tacatacgga cagggtcatt gaccttagca gaagttgacc caatcaagtc
     6481 ctcatcgctg agttctggtt cttcttcatt gctaagaaca cgcgcacttg gatttccttc
     6541 gttatctgtg atagaaattc ctgcatcctg aatccgttgc aagagatctt caatcccatc
     6601 agcgtccaag gtaaaaggaa taaccaaact tgcattgatt tcatcatctg ttgctgtccc
     6661 tttttgctta tgattacgga taaattctgc tacctgtacg tcaaatgttg ttacttcttt
     6721 ttgttttgtt gccattatta ctccattctt ctcttttggg aaattaaacg ttccaattct
     6781 tctagggctg tatctgtatc tcctacatgg ctagcttcct gcaccttctt tttgattctc
     6841 atattgtcct gattcaagag agccttgttt cgagtcatct ctacttcact aagttcctgc
     6901 ggcgatatct cagcaggcaa atcctgagct aaaacttggt accaagctct ttcaacttcc
     6961 tctgtctgct ctgctaaaac ttctggagga agatttccat actggccaag caagtcatat
     7021 aagacctgaa attcaggtgt agcaaatgca aagtcttctc gcaaacggta atcgttcaaa
     7081 acaagagggg attccatcat ccgatagagt agatgggctt ctgccctcat aatagccgat
     7141 aactgcttgg tgacaggcat ggtgattggc gtcggtctgg aaattctttc catgcgattc
     7201 tgcctttgca cctgacgact ctcattaaca atctgctcaa tctgggcata atcaaaggac
     7261 gccagactgt cagctaaaat atgaatatag ctgttttgag cagcgatgga cttttcttta
     7321 acaatcaagg gagctatttt ttcaataaac tcaatctgag cctgcagatt ttcactgttt
     7381 tcaggtttgt actgatgaat gtagaactca atcggactaa tacgagtttt cgttaataga
     7441 taggccaagt cttctggacc atttttttgt agatactcat caggatccaa gttatcaggc
     7501 atgctgacga tttgcacagg catatcacca atttcatcca atgctttcaa tatcgcggct
     7561 tgcccagcct tatctccatc gtaaacaaga accaatttct tggttaacct tttcagatgc
     7621 tcaacatgct ctcgactcaa ggccgttccc atcgacgcca cagcattttc gattccaacc
     7681 cgataggctg caataacatc catgaatcct tccatcaggt aaatctcact agcttttcca
     7741 gaagattttt ttgccctatc catatgatat aattcgtaac ttttgttaaa aattgcagtc
     7801 gatcggctgt ttttatactt agaagtttgt gaatccgttt tttgccagat acgacctgag
     7861 aaggcaatga tctttccttg gtcatttgtc aggggaaaca taatgcgatt gtgaaaggtg
     7921 tctacaaatt gattggcatc cgagagataa aacaggcctg aatccagtaa atcctcttca
     7981 cgatactgat cagacaaacg ttgatagaga tagtttcgtt ctggaggtgc taaaccaatc
     8041 caaaaatgtt taagcacttc atctgtcaaa ccccgctgat aaaggtaatt tctggcctct
     8101 tctcccatag tcgttgtcat gagaatagca tggtaaaatt tggctgcatc ttcgtgcata
     8161 tcataaagag cttggtgagg tgaggctgac ttctgctcac tataaagcgg tttttcaacc
     8221 tcaattccaa cacgctgacc taagatttgg actgcctcta taaagggaac cccttggtac
     8281 tcctcgatga acttaaagac atcacctgag cgaccacaac cgaaacagtg ataaaactgc
     8341 ttatcctcta caacgttgaa agatggtgtt ttttcgccat gaaaaggaca gagccctaga
     8401 tagttccgtc ctgccttttg taaagaaatc acatctccta tgacttccac aatgttggca
     8461 ttgtttttga tttcttcaat gacttgtttg tcaaccatac acaatacctc catgttatca
     8521 tagtatacta tatatagtat actttatttc agaaaaaaag taaactattt cactcatttt
     8581 ccctacttta ttcaaagagt tgataataat cagagatttt catttttgct ttttcttctt
     8641 ggtttaaatc ttggataatc cgtccttctt tcatgacaat caagcgattg ccgtatttga
     8701 gagcatcttc catatgatga gtaatcataa gggctgttag ctgatctttc ttaacaaatt
     8761 catctgtcaa ttccatcaaa gcaacactag tctttggatc cagggcagca gtatgctcat
     8821 ctaacaggag taattcaggt cgcttcaagg ttgccatcaa gagactcaaa gcctgtcttt
     8881 gtccacctga taagaactca atcggtgtat tcaagtgttt ctcaagacca tttcctactt
     8941 tttcaatggt tacctgaaat tcatccttat agctagtcaa gcgtcgtggt aacaatccac
     9001 gcttttcacc acgaaacttg gcgattaaaa gattttcagc gaccgtcata cggggagctg
     9061 tccccatctt tggatcttgg aagacacgag acaggtactt ggcacgcttc tcgggtgaaa
     9121 acttagtgag atcttcacct aaaatacgga tagttccact agttagtgat aaggtccctg
     9181 ctatagtgtt aaagagggtt gattttccag caccatttcc gcccaaaatc gtgataaagt
     9241 cccgttcaaa aatttctaag gaaacatcat ttaaaataat cttttcttca tcaaagccat
     9301 ttttaacgat tttggttgca ttttttaatt ctacaattgc tgtcatttgc ttaacttggc
     9361 tcctttcaag attgtttgct taaatgttgg aatcatgagg cagactgcta aaatcaaggc
     9421 actgtataaa cgaaggtaac ttgtattaaa gccaagtgcg ataactgccc acactaaaaa
     9481 ttgataagcg atagaaccta caacgatagt aaccaaacgc tctgccaagc tcaaactctt
     9541 gaaaataact tctccaataa tcaaacttgc aagccccaca acgataaccc cgatccctcg
     9601 agacacatcg gcataacctt cttgctgagc aatgagggca cctgcaaggg caatcacacc
     9661 atttgataag accaagccca tgagctccat gcgtccagta tgaatcccga aacttctagc
     9721 catatcagga ttatcccctg tagcaatata ggcttgtccg agtttagtgt ccaagaaaaa
     9781 gagcatgaga gcaataacaa tactcacaaa gatgagacct gtcaagagtt gattcaaatc
     9841 cgaatcaaaa ggcaaaacat cctgaatttg cttggttcca agcaggccta aattcgcacg
     9901 tcccataatc aagagcatga ttgagtgaca agaagtcatc accaaaatcc ctgagagcaa
     9961 ggttgggatc ttcccttttg tataaagaag gcctgctgcc attccagcca aacaacctgc
    10021 tcctacagca acaagtgtcg ctaaaaatgg gttcacgcct ttggttatca aagtgacagc
    10081 aacagctccc ccaagaggga aggaaccttc tgtcgtcata tctggaaagt ttaaaatcct
    10141 aaatgtcata aagattccca gacctagaat agcccagaca aatccttgag aaataatgga
    10201 aacaatcata ttttatttaa tcctttctat attcatcttt ttaaaaaatg ggaagagtct
    10261 cctcctccct accttattta ttcgatgact tgtcctgctt ctttgagaac agactcaggg
    10321 atagtaatac ctagttcttg tgctattttt ttattgatga ctgacttacc agttgaaaag
    10381 acattgactg gggtatcggc tggttttgca cctttcaaga cttgcacaat cattttacct
    10441 gttgccacac caaggtcatg ttggtcaatt acaactgatg ccaaaccacc tacttctacc
    10501 atagctgtcg cactgggata aattggtttc ttagaacttt gattgctaga gacaaccgtt
    10561 ggaaatcctg atgcaatggt gttatcaatt ggaacccaaa tagcatctac cttgctagtc
    10621 ataacagtga cagttgaggc aatttcattt gttgaaggaa ctgcaaatgt ttccactgtc
    10681 agacctgctt tttcagcata agccttaaat tcttcgacct gtgtttttga attgtcttcg
    10741 ctacttgagt aaagagctcc gattgttttc acattcggtg tcagagcctt gatgagttca
    10801 acttgttgtt gagctggatt gtggtcagat acccctgtaa tgttgccacc tggttttttc
    10861 aaatctttaa ccaagttagc accaattggg tctgtaatag cggccatgat aaccggtagg
    10921 tcttttgttg cactagccaa cccttgggct gctggtgttg cgataccaac cacaaggtca
    10981 ttcccatttg caaccaattg tttactcatt gtcgcaacct tactttggtc accttctgag
    11041 ttcataaaat caattttaac ttgatcatct ttatatcctt cttctgcaag tccatcttgg
    11101 atccctttat aaatcaaatc aagggatgga tggctcacaa attgaagcac accaatctta
    11161 gttattttct tctcatcctt attattctga gcttctgatt tattcattga agaataaatc
    11221 aagcttcctg ctactaagac tgctaatgca gcaataattc caattaaacg tttatttttc
    11281 attctgtttc tcctttttat ttcctttaac atatttcact tatctaaaca agcgacgcca
    11341 tcgttttctt tccatactaa cctccatcaa aaaaatcctc acacaaaaaa cttgtgtgag
    11401 gacgtcgatg cgcggtacca cctcaattat agggaatttc cctatcgctc agtctcgcaa
    11461 taacgagatg cactgtaagg tgtgcttacc gaatttttat aatttcaaat tctaaatagc
    11521 attcagccca attttcatca tcgccactta tctgttttca gctaccacag actctctaaa
    11581 aagtttgtat gattactttt ctgaatggtt aaattatatc atttttaaac tacttgtcaa
    11641 tagtctatta gaattttttt gatattcact tttagcattc actcttgaaa attatcaacc
    11701 tgaattacgc aatcctgtcg caattccgtt gatggtgata tgaatcaatc gttcttgatc
    11761 actggacaat tctccacgac gttggcgttt aatcaactct aactgaatat agttgagaat
    11821 attaaagtaa ggcatacggt aatccagact agcttttaga tatggattgt cagctaagag
    11881 ttcgtcatgt ccttcaatag ccaagataac gttcttagta acttgccatt catttaaaat
    11941 aatctcatag atggccttaa cttgctcgtc ttcacaaagt ttagcatatt caaaagcaat
    12001 attcatattt gattttgaca aaaccatatc aacatttgaa agaagcgatt ggaagaaagg
    12061 ccaattttgg tacatatctc gtaagatagc aatattctct ggatttttat tgataaattc
    12121 cttgaagctt gaaccaaccc cgtaccatcc agggaacata acacgactct gtgaccatga
    12181 gaatacccaa gggatggcac gcaaaccacc gatttcagta atagtcttac gagcggctgg
    12241 acgagaacca atattaaaac ttgaaatagc cttgattgga cttgactcga agaaataatc
    12301 atagaaatgc tcattaccaa agaccaaatc acggtagata tcgtaactac ggtccactac
    12361 ttgatccata atggcttcat aacgatttgg ggtattggta tcgctcttct tctgagtaat
    12421 catacggtta atagctgccg atactagcat ttcaaggtta tagtaagcgg cgtctttgtt
    12481 accgtattta ttcccaatta cttcaccctg ctccgtcaaa cggatacgat ccttgataga
    12541 cttgagcggt tgagatgtaa tggcttcata ggttggccca ccaccacgac cgacagtacc
    12601 accacgacca tggaagaagg taaccttaac gccaaattca tctccaatag cagtcaattg
    12661 ttgttgagcc ttgtagaggg tccaacatga tgacaagtaa ccgccatctt tattactgtc
    12721 agagtagcca agcatgattt cttggtagtt atttcgtgag tcaatccatt ttttggcaag
    12781 gctaagagaa agatattttc tcattgtttc ctctgaatga tccaagtctt caattgtttc
    12841 aaaaagggga acaatctgaa cacgcgccct ttccgtatcc accagtccta cttcttttaa
    12901 cagaatagct aattctagca tatcagaaag gttggttgca tgtgaaatga tggtctgacg
    12961 gatgacatca tctcccaact tatctttcaa aacacgagcc gtcttaaaaa tagctaattc
    13021 ttttgctaat aattctgatt tttctgcgtg agtcgcagaa agaattcggg gatcttcttc
    13081 taattctttc aagagaaggt cacacttttc ttcttcgctc aactcgctat aacgagaatg
    13141 aattcctgct gatttcaaga gttctgccac acaggcttca tagacgctag agtcttgtcg
    13201 catatcaatt gatgctaagt aaaaaccaaa tatctctact gcctgcaata attccacaaa
    13261 atcacctgaa atcaaggact cgcccttatt ttctagtaga gaatctcgaa tggcaatcaa
    13321 atccttgtag aaatcattgg cggtttcata acgagtccca acttcttcat cctcaatcag
    13381 ataggtttta gttgcctgaa tttttgattg aatatcaaac aaggcacgac ggtaaagctc
    13441 tttttcgcgg taaatcgagt tatccttgga ttgacgagcc atttctctga cttgcttgct
    13501 gacgttgaca atgctagttg aaagagaaaa ttcacgataa agttggtaaa tctttttatc
    13561 atagtagttc atgatgactt cacactgagt gagtgcagac tgcttcaagg tctttgctgt
    13621 aacaaatgga tttccatcac ggtcaccacc tatccacata cccatggtga ttggtttagc
    13681 ctgttttaaa ttcagaccat gcgcttgcgc taagcgctta tactccgtcg tcaaatgagg
    13741 tacagctttc aaaaaggagc tgttataata ttccatagca ttcgtgattt cgttagtcac
    13801 ttttaatttt ttctcacgaa tcatgtctgt ctgcatgata atttcgatgt aacgacgcaa
    13861 atcattgtac catttatctt tattgatcaa ccccaactta acatcacggt atttacgcaa
    13921 aagactatga atatgatttg ttaaatccaa catacttttg cgttgcactt gtgttggatg
    13981 ggctgtcaaa acagggacaa cattcaagtg ttctaggatc tcaacggcat tttccttttc
    14041 tgctaccaat ttaatcgttg tagataattt acctaaatag tcctgatcaa tattattttg
    14101 atgattgatt tcataagcta aatccacatc ctctgaaata ttaatcaaaa gaggcaagat
    14161 agagaaatag cgtgaaatat agaccatttc atcatttgat aagctagtca ctagacggtt
    14221 tagaccttga taatcttcct gcgttgataa ttctttcaac tgtattattt tttcaaaggt
    14281 ctctggggca agcatatttt tagtaatatc ttccagtaat tctgttagaa tcaagacttc
    14341 ttcttgcaca acacttttat tactataatt ttctaatttt tgaagagaca taaactatcc
    14401 tttctttatc ctacttcaac agaaggttca ttggttgatt ttccaattct cggtacaatt
    14461 tagcgcgttt ttcactggca tcaatattta agacaaaggc tactgccact gataagacta
    14521 gaagactatt tccaccctgg gataagaagg ggaaagtcac tcctgtagat ggaatcaagc
    14581 ccgaaatccc tccgatattg acaaatacct gaaccaacat catccctccg acaccgagtg
    14641 caaccatggc attgaaagga ttctccgctc ggataccgac caagataatc cgcaaaatca
    14701 tgaaaaacaa gagagctaaa ataagactgg caccaacaaa gccaaattct tcaatcacga
    14761 tagaaaagac aaagtctgta tgagcttctg gcaaataacc tcgtttttca atcgagtttc
    14821 caagacctag accaaaccaa ccgccattga ccatggcaaa ataagaatta gctaactggt
    14881 gacctgcatc agcacgatcg gcaaaaggat taaaaaaggc actaaagcgc ttggctacat
    14941 agccaaatac tggaattttt gaaaaggtct caacaccgat taggctgata gtggtcaaga
    15001 caaagacaga agtggcagat acgagcgcca gaatggttga aaaccagcga taagcgattc
    15061 cactaactgt atacataatc aaggaaacca agactaaaat agtcgcattt cctaaatcag
    15121 ggaaaattcc caaacttcca atcagaacta ggagaacgaa tcgccaatca ttaaaagcac
    15181 ggggaagcca ttgattttga gtcaaaactt gaaaatcata agtagctatt tcttcttgct
    15241 gtttggagaa tcggtgagct aaataccaaa taataatgat ttttaagtac tcagctggct
    15301 gaatagttac tcctgcaacc gaaatccaac cgtatgcccc gtttactgaa ataccaataa
    15361 aacgagccaa gaacaataaa agcatttcta ttaatataac taaaatgatt agtcgctcat
    15421 ttctcaaaaa atctagtctc aatttataaa ttaaggcaat cagtatcaaa ctaacaatcc
    15481 aaaagattcc ttggtttcga accaactgca aggcgctctt gccttcttca attaaaatag
    15541 cactggtggt cgaatagacc acaatcaagc ccaaaataga taaaagcaag tagggaatca
    15601 agatggaata atttaataag tgcctcttac taatcttcat agtatcacca ctctactagg
    15661 atacagacaa atctgttcca aattccgttt tattttctag ttttgattgc tattatacca
    15721 ttttttcaga aagaaaaaaa ctcttacctt acaatccttc gaattttact gtttttacag
    15781 aattaaggca gaatttgaaa tcgtaaaacc attttgaata agagttgctt caatccattg
    15841 actccgacta attatgttgc tttcgtgaat gccaaaatca gccgcaattt gttcataagt
    15901 gcgctattct cgcatgtatt gaatagttac cataaggaga tcgtctaggc ttaatttgct
    15961 ttttcgtcca ccttttgcgc gtttacgttg ataagctgtt tttaacaccg ctaacatctc
    16021 ttcaaaagtc gtgcgctgaa cacctacaag gatcttgaaa cggctatcgc tcaattgttt
    16081 acttgcttca tcattcatag ttttattgta ttatattttt gtttcgcagg aagtctatta
    16141 ttcctttcgt tccaaggttt ttacgctttt agcaacaagc ttacacactc cacgtgatgc
    16201 gtctgtagaa ctcaaaaggt tcggggaacc ttttgaggat taattgcgtt tatctaacaa
    16261 actcacacat tcaacatggc atgactgatg aagtcatcat aagaatttca cttgctgctc
    16321 ttttacggtg gcagcctgaa cggtcagaag tatcattgta tatcatttgt atcatggcat
    16381 ataaagtatc gctctatttt attgatggtt ttaatatcgc tcttatcatg gcgaaccatt
    16441 caaatctgct ccacaaatga ggaaagtacc attttggact attcaattgt caaagaacaa
    16501 ataaaaaaaa tcttcgcatt ttcacactct atgaaattga ggagattatt ttctaaagcg
    16561 aattttatca ggaaaatccg tcaatcccaa taggtagtct gtactgacat cgtaaaagtt
    16621 tgagagagtt accaatatat ctgctgttaa cgtatgctca ccccgttcaa ttttagcata
    16681 agctgagtct gtaaacgaaa gtattttagc tatttgtttt tgggtcaaat cgtgatcttc
    16741 cctcaaatct ctcaaacgtc tgtacatcta gctttctcct gagaaaagta taatatataa
    16801 aactaagaaa tcattcaaag tgtccaaact ggacattttg aactaaaatt aatttattaa
    16861 acatatctca taagcatatc tattataggt aagacaatat taagaaagac ggtcaaaatc
    16921 tattaaccgt ctaaagatgt tataagctat taaaaaatca gcagtaatcc ggtaacaaaa
    16981 gtcacataat tttgttaagg aagggattaa tgatgtccag attactacta accagcaaat
    17041 tgaaaaatgg tcaacatgat atttctaatg tgaatctctt actttcagaa cctaaaagct
    17101 gaataatagc caccccctac ttatcaataa aattttccgt tgcattaaca gatgtatata
    17161 gaccactcca tggatttcaa agcaattaac tagactttat ttgtcaataa ccacaaaatt
    17221 agattagaaa aatcattaaa aattaattgg agtcctttgt gatgcttttt caataaaagt
    17281 aatacttctc aatattttaa ctgaactaaa gaaatagcat aatggtatct tgattgtatt
    17341 cttctaaaaa ggattgccct tcacattcaa ctgtgattga ttaaattcca aaaatatatt
    17401 ccaaaggcgc tctaaattct ctatatcagc tattttttat catctatcaa cttctatcat
    17461 acctcttcaa tagcgtgcta aatattagcg ataatatcgt aatagataca ccaataataa
    17521 aaaaattaaa agtattgtta ggatttaaaa ctactgagaa aaaaacagta cctagtggca
    17581 taaaaagaat agctaccgta aagatgattc caaatactct gccaagaaac tcattatcta
    17641 cgtctctttg aacaatagag aaaaattgga tattaaaaat ggaaagaaat agactaaata
    17701 atgctggagt aaaggctaaa ataatgacgt tgcggaacat ataatagatc ggcgctgtta
    17761 gcattaacat caaacctgaa tatgctaaaa agagcattaa acgtttgctt gacaaggatt
    17821 tattgataaa tccacttaat atcgcaccaa taaagccacc aatcgcttcg gctgttaaaa
    17881 aggttccata tagcccactt gaaatacttc caaacatttg attactgtat ggcagcaaca
    17941 aattataggc tgctaggaaa aagttaacaa gtgctgaaag ggcaattata gtgagaattt
    18001 gtttatgact atatacatac gtaaatccta tttttaaatc atcaaagatt cctcttatcg
    18061 tcatattctc ttttgtatcc acctcctcat ttacaggagt aatgaagaaa attagtgagg
    18121 cagcaattaa aaacgataat ccatctagta ataacacacc atgtattcca agtaacttat
    18181 ataagaaaat tgcaatcata ggaattgtta ctttaatcac agtacttgtt gtttctagca
    18241 atgaattaag ttatgatata ctgtcctttt ttacaatttc tttcgtaaaa gctttgtatg
    18301 atggccctga aaaagcactc ataaaagcca aaatgacatt tgttatgact atcgcataaa
    18361 ccaaccattt ttcttgggat ataaatgaaa gagttatgca agcaatacca cataagatat
    18421 ttgtagtaat aataattttt ttccgcttga aactatctgc aataactcca ccaaataaat
    18481 taaatagaac acctatcata ctttctaatg attgataaat tgcaaccact gatagagatg
    18541 ttggattaag accagcaaga aaggtattat tggcgaaatc aaacatgata tctccgattc
    18601 gagatatcat cctactagct acaatggata gaatattgtg atgttcttct ctaatcattt
    18661 tattctcccg aatcagtaat cacatattta aacttttgtg atatgtgctt aagttcatct
    18721 aaccttttct caaattcaca actatttttg caattaaatt ggacaaacat tgaattttcg
    18781 actacatttt cagatacttt atagtaagta tttggtttaa taaatatgta cacttttttt
    18841 gcccaagcca attctttttc atcaggtacc tcgataacct taccttgctt tctatataaa
    18901 gcaaacgttg ctgagatatt agcaggtcta gaaatcactt tagaaaaatt tatttttttc
    18961 aatacttgtg aattagtcaa aatatcccaa tattctttaa ttacatcaac tccatgacta
    19021 tcctcaatta actggggaat atctccccct ccaaatcttt ttccaacttc acaaaagact
    19081 attttaccag ttgataattc aaggaaccat tcaaaatgaa aaggggttat ttcagaattg
    19141 atagaaaaaa cattcaaaac tttgcgacat tcttccaatg ctttttctat gtattcaatt
    19201 ttttcactat cattatataa cgaactagtc cttacaagat aatatccact agaacttaag
    19261 gtattgaaca atagttcctc atattcgtga acataaaatc gcttaatctc acttccaatt
    19321 gaataaccat cacatgttat catgttatcg atatcaatgt attcctctat aatatagttt
    19381 ttttcaaaat acactgaatc aattttctcg ttagggtaaa ctttttttat tccattactt
    19441 cctgcttcat ttctaggttt taaaattgca gcagaagatt tacaattatt ccaaaaaaca
    19501 cgtaaatcat tttctgattc taaaagccta aaatacggtt gatttactac tccaactaaa
    19561 aatgaacgca tgaagtattt gtctttaaat aataaattag acacagagtg agtatttttt
    19621 tctacaaaat gatcattcaa aaaacctact atatccatgt cttcctcact caaggttgta
    19681 atactctcaa cttctgtatt ttgacttatc cttctaattt ctaagatgat atttggtaga
    19741 ataaaatctt ctaaaaaaat gaccttaggt agattatttc cttcagctag ataatcttca
    19801 tatttttttc tttgaacctc aggtgcaata attactacat ttctgttata cagatatttt
    19861 agtttaacaa cccgtgcaga atatctaaat aatactatat gcatgttaat cccaatccca
    19921 atcctttcaa ttattagtca tcatatccat ttggatgttt ctgttgccat ttccacgtat
    19981 cttggcacat tttcataata tcataccttg gcttccatcc cagtagctct tctgcttttg
    20041 aaatatctgc aattgaaacg tccatatctc ctgctctcct tgaagttatc ttatatggaa
    20101 tatacgagcc tatgacactc tctaagctgt gtaggatttc aaatacacta aaaccaacac
    20161 cacttcctaa attgattact tcatataaac cttcatctgt attaaaaata tactctaatg
    20221 cttttctgtg tccgtctgct aaatcgttaa cgtgaacata gtcccttata caagtcccat
    20281 caggagtact gtaatcaact ccgaatatat ttaaatatgg taattttcca attgcaactt
    20341 gtgtaatgta aggaacaaga ttattcggaa ttccatttgg atcctctcct aaatcaccac
    20401 tttcatgtgc acccaatgga ttaaaatacc tcagacaaac aattttccaa tttgaattcg
    20461 aaataaacaa atcatttaaa agtacttcta tatactgttt tgttctccca tacgggtttg
    20521 aagcttttaa tggattagtc tcatagaatg gcatgatagg agtactttcg tatacagtag
    20581 ctgatgaact aaacacaaaa ttaaatacct tatatttttt cattagtttt aaaatattta
    20641 tagttgataa taaattattt tcataatact tcaatggttc aaccacggat tctccaacag
    20701 ctttataccc tgcaaaatga attactccat caaaattatg tctcttaaaa acattttcca
    20761 atttttcttc attttttaaa tcaattttat aaaaatgaag atttctactc ttcttggata
    20821 tctgcttaat agactcaata acttttttct tagagttact caaatcatca atgattgtta
    20881 cttcataatt attatctaac aagtccaaaa ccgtatgtga tcctatgtat cctgctccac
    20941 ctgttattaa taatgatttc atgctaattt acctccatat tctttatgcc attaatttga
    21001 aatttatctt ggctaaaaat taccctattt gattttgctt cacttccaag aaagttaccg
    21061 atagaaattt ctggaaattc aaaaatcttt ctagactcta atttatattt gtctatgtct
    21121 aacaaagtat attttccata ttgattaacc agattggaat tattaaacaa gatcaaggga
    21181 tagttatact cccttggtaa ttctgctgta atgattgaat tttgattttt aaattcgaag
    21241 ttaaattcac aaatcccttc cctaaaaaaa tgaagctcta catcatcaaa tacatagtta
    21301 cagtccaatt ccttatgaaa acctagataa aatcctctta ttaacgaata gggatttgaa
    21361 acatatgata caaccggaaa attaaaataa tcttctccaa tacaaagagg tatcttaaag
    21421 attatttctg tatataagat ttcattattt tcattaattt ctgaatacat atcagaaaag
    21481 gtaagataga atgattctac tgattgtagt tgtcgataca attcttgatc tagagactta
    21541 acatctgggt ataatacact agcatcaact gctttattta gtttaacttc tagagttata
    21601 ttattacctt taaatttatt tggtaatctt atcatagtta ccctcccact ttaattttta
    21661 atattttaga aactattttg tcaaactctt caatagaaag tgaagtatca ataaatggaa
    21721 tatctgtaaa atatctaacc tcatctaatt tatgattaat ttttatatgt aaattctctc
    21781 cgattaagta tctatatact tcatttgtta ttccatacct atcactcaag atatctctag
    21841 ggtacttttg aattaacttt ggatattttt tagtaatatt gtcaatttcc ttcattaaaa
    21901 agtagatata atcatttctc aataaatgat ttactttcgt tatatcaagt ttggtaatta
    21961 ctgagtataa agcgaatttt tttagtattt ttttcactgt gtgcccttta taatttcctg
    22021 aaatttcaat atttttagag gataattgaa taagacaatc caacaaggaa actactcgaa
    22081 tattttcttg gctatcaata aattctagaa acaagctttc tatattgaaa ttagaggtat
    22141 ttccaaaaaa tttaaatttt tctggaatct ctccatgaag aaagtaatcc aaaagtttca
    22201 ggtagaattt attaatattt atctcaaaat atttcttaga ctgaatctta aattccgtac
    22261 agtcaattat aggaataaac tgtcctccat ttttcacaaa aattttaaaa taatttccaa
    22321 cttttgagtt ttcaataaaa aatggaatct cttttgtaat aatataatag tctctatcaa
    22381 ttaaattcct aattaggtgt tcgtttgaag taataacaac aaaatctaat gttttagacg
    22441 aaataacttc tatttctctt agaagactag ttaaaaaatt cattgctaat gaatcttgtt
    22501 tattaactaa taagaaatta taagtttgat tatatatttc ccaatacgga tttatatatt
    22561 ctaaatccaa gattcttgtc caaattgttt cctggggata gaaatatatc ccttccttaa
    22621 ggctttcata gtcatgagcc attaacgctg aacctatgaa ccaatcacct ctcaaaaaac
    22681 cactatcttt cagtgtaaca atatcatatt tcttaataat ttcagaaaac attttctatc
    22741 ctttcactct atataagcac caaatcattt ctggagagaa agtttcacaa ataataatat
    22801 catcattatt aattatcgtt tcttggctta ctattgaaaa acgataacct tcttccagaa
    22861 attttttatt tgccataact ttactatggg taaaatctat cctcagatcc atactttttt
    22921 tctttaaata gtttaacatc aaaatctcag ttgcaggttg gataatcgcc ctattaattt
    22981 tataattaca attctcgatt agaaccattc ccttagtaaa agagtgaaaa gaatccacaa
    23041 tttcaatccg cttatgatat tcaaagttga aatctttcca actataattt ttaatactac
    23101 tctcgaaagc tacaggtaat aatatatatt gcccttttaa tttatcaaag caattaacta
    23161 tactatcaaa actatcatac agtacaatca catctacttt taattttata cgatttattg
    23221 cataaaaaca atctgttgca gttggtccta atgtatttat tatcatcttt cccccaagct
    23281 caaaatacaa tgttcaaagt ctaatccttg attttccaaa gatactaaat ccctcatctc
    23341 taaataaata ttctcagaag tttttacatt ttggaaaaaa tattcacttg aatccaaaat
    23401 ttgtattttg tgttctttta aaacagcaaa tattctttca aaatctaggt gttttatctt
    23461 tttatcgata tgatttaatg ttgcaatctc cttccaatac ttttctagtt ttaattccaa
    23521 ataattattc tttgaaatta aatattttga tgaataataa caaaattcct gaatcataga
    23581 gcgagtctgc tccacaatat tggtaggtga gtctaaagct tctattattt gattttttat
    23641 atgcagatta tctactaaaa gattatctac acttctaata ctattaataa ttccacgata
    23701 acgacttcga tttattcttt ctttcaaaca aaaaatcaaa gaaattttat gtacaaagtg
    23761 aaaccttccc tctaaagtct tttttatact aattaattgc tgaatactgt ctactataac
    23821 tagaatatca atatccgatt ctaatttccc atccttgatt cttggattac ctcttgccaa
    23881 ggaaccagta ataacgagtg aaatttttcc tacctcgcat tttttaaaaa atgaaattag
    23941 tatatctaat tctttagaca gcaagtcatt cctataagtt atcatacttt cctattaccg
    24001 tataatcttt tccactatca gttactaagc aatccctata ttgctgtaat aaataattta
    24061 tttctttcac ttcatcatga aagactgaaa aattagcata ttctaaatct tttaccatat
    24121 attctactct aaagtgtatg tcatcaaaat cttgatcatt gatctgttct aatttggagt
    24181 tgcatactaa actcatccaa ccatcattac atacgattgt attcgctacc tctagagact
    24241 ttggtgaaaa atcatactgt aaagggttga atagcttaat agagtaaagc aaatacgctc
    24301 cccacgagtt ataaattaac ttgaattttg ttggttccgt actcttttca aaaaagtata
    24361 ttttttttga aattaatttt aataattcca ttaactcctt tttattatag tttacacctt
    24421 catcaatatg taaaaaaatt gatagttgac cactattact tcctaactta cctcctgtga
    24481 aaggagcctc tatatagtat ccccctttaa tttcaacagt ttttttaaat ttttcaacgc
    24541 aatcaatcct ggaggttgta aaatcaatta ctatggtttt acgaagtgat tgtatattta
    24601 ataaaaactc attaatgaaa ttatccgttt caatatgatt actaaaacaa gtgattataa
    24661 aatcaacctg atttatagca tcaggtaatt catcttctct aataaatatt attccattta
    24721 ttgttgaatt tagatgccta ctatataggt atatattata ttttttcgac tgtttcagga
    24781 tttttaatat accccgagtc attataccat accctataat taatactttt ttatgtttca
    24841 aagtctcacc actctctaaa attttacgat ttaacttaaa tatgttttag ctagtaagta
    24901 tagtctttag atactctaaa gacttaggtg tacacctaag tgatttaacc accaacaata
    24961 atgataatgt ccatcactag catcaaaatt gggaaaaatt ttgaaatttt cttcatattt
    25021 agacttcctt tcaattttta tttattgtac aataaataaa actaagttaa ctttttgttg
    25081 ggaaaatggg aaaaactatg aaatcaaaac ttggcatcac acttagaaaa gttcgtaaag
    25141 gcaaacaaat cagtctatgc tctgttgctg atgagcatct ttcaaaatcg caaatatccc
    25201 gatttgaacg tggagagtca gagatatcat gtatccgact gatcaatatt ttagacaaat
    25261 tacacattac tttggatgag tttcttattt tacacgatga agactataca aaaactgagt
    25321 catttgccaa cttaatacag tatatccgta aacaatattc attacaaaac atcaataata
    25381 tacaatctct actttcggat tcctcaaatt acactttaga ttcttttgaa aaaacaatgg
    25441 taaaatccat tttacacaca atggattcaa gaatcattcc atcagatgat gaattacttc
    25501 aactagcaga ttatctcttt aaagttgaaa aatggggtta ttatgagatt attttattag
    25561 gtaactgtgt acgaacaatt aactacaact cctacttctt acttaactaa agaaatgtta
    25621 aataattata tttactcatc tctaaataaa acaaataagc ggattgtcac tcagctagct
    25681 ataaattgtt tcattctcag catagataaa gaagaatttt ctaattgctc ttatttaatt
    25741 aatgagataa agggattgtt agagaatgaa ttaaactttt atgaacagac agtttttctc
    25801 tatgcaaccg gttactatga atttaaacgt caattaagta gtggtattga aacaatgaaa
    25861 caagctatac aagttctcga tattttagga gaatacaagt taaaattaca ctatactgac
    25921 cattttaata aactagtaaa taaaaaataa atgaaattat tctctatctt ttaactaatt
    25981 agtcgtaaat aatattattc tagtaaggca ttctcgtgaa attttagaac tgtaaattta
    26041 ttggtattaa taattttcac aaacaaatcc aatcttctag ctatctcctc atatttatta
    26101 atttcattac caagttcctg ttgtaatttt aaaatatccg tattgagtcg atctaacatt
    26161 attgattccg tcatgttcat ttggtcaaaa tcatacttag ctaattttct agtctcatga
    26221 tcttcactct tcaaattgat aaggacttcc gccatcttgt ttaaggtggc gattttttct
    26281 tgggtttctt ctagctgcat atcaatctct gcaatttcta atacaagctc atctttgatt
    26341 tcttggtatt gtttgttcgt gttagatagt tcaatcataa gattaatttt agaaatcttc
    26401 tcttgaagac tttttaaagt tggtcgtcta taggggagtt tttggctatc gttgctcaat
    26461 tgtctgatta aggtcctacc cttgatgaaa caattattat ccatgttttc tttattatag
    26521 acaaagtaag aagacgtttc tcgaatgtag actttatatt ttttctgatt gtcttcttcc
    26581 atagtatcca attgataatt gggaatgaaa ataagaccac tctgcttaat accaaaagac
    26641 actttgatat aaattccctc atcaactagc ttctctattt ggttctctgc aagttccact
    26701 tcaaattcac gaacagcatc tctcttttcc ttaaatatct caaaggcttc ctcaatctct
    26761 tcagtggata ctttatcctt atctcgttct tcttggaaag catggtactg ttcctataaa
    26821 ttctctaatc cttctgaagc aacgacttcc ttatttttaa aataatcttg aaaaaatttg
    26881 acatcatata atttcttatc acttattttt tatgacccaa acttatcttt tgattatctt
    26941 cttccaggat aaaagttaca tttttttgtt ttaagtcaat ggttagattc aattcttttg
    27001 cttttgttat taactcttct aaagaattga cacggttcaa caaaaattct aaatgacttt
    27061 caatctcttg tttggcaaaa tatgttttaa aaaagtcttc atcatataaa tctcgtttac
    27121 taagttggcg acctcgaatt ggttttatca tcgttctatc tgtcatcaaa aaacggctat
    27181 gcttttgact aaaatcaatc tgaacatgca actgctttgc tttctctaaa aaatcatcaa
    27241 acgatttaga ttgctgaagc aaaaaataaa gacgttgttt caattcaaat ttatgactag
    27301 attccttata ttttttataa tctcgatagg aataacgttt ctcaataatt tttgcaccag
    27361 ccattttaga aatacggtct gaaatcatac ggaggtttcg ttccaaggca tagttccata
    27421 tcaacttttt atctgaattg cggtcaatag cgttaattag gatgtgatta tgaacatgat
    27481 ctttgtctgt gtgagttgct acgataaact taaaacgacc tcctgtcaat tccatcatgg
    27541 tctcataacc aatgcggtta atttcttcag gtgtcagatt atcttcagga gaaaatgatt
    27601 ggatgagatg atgggcatga atagtttgtt ggtgtttttc ttgtcggtca tttctggact
    27661 cgtacaactt gtcgttatta gtaaagttaa cattgtacat ttctaccatt tctgcatggc
    27721 taggaaaatc taagtaatta ctcatgccaa aatcagatac taattttaga ttatctgttt
    27781 tatctggatt gaggatatat ttaatcaaac gcctacgata tttttttccg tgcgtcgcaa
    27841 agtatttagt aactaccatg aaactccttc agtcttttca cctccacttg aaattctttg
    27901 tccacttcct taattaactc tccgactcct ttactcaatt cttgtaattg gtcctgagaa
    27961 atcagatggc tttgattaat cgcacgcgca atttgattga tgttatttcc aatcctcctc
    28021 aattcaaaca ctaactgttc ataagtatca gtgttaatcg tgacaaatga catattggga
    28081 ttaagcaaaa cttttctggc gtagactgag aaattttgac agtgactctt agtaatacga
    28141 tcatttaatt aattcaattc tgaatcagtt agaaatattt ttttagatta gtacgataac
    28201 gataaaccat agcagtctcc tatcccatat atttttcaca gaattcacga ctgagtggct
    28261 gagcttgatt gacttctaca attaattctt gaacacaagt caataagatt gagacgtgct
    28321 cttgagtcac ttgatgattc tctcttgcga taatcaaaac caaatgcaca tctcgactga
    28381 tctgttcaaa cttttgagac tgccaaaggg aaaaccattc tttggcagct aactgtttgt
    28441 catcagtcat caaaatttta tccctgacga atggtgaaaa gtgacgataa ttatcaacct
    28501 ccatcatttt ttcaatctgt tttagctcat ctgcggttag atttacctct tttcgaatgt
    28561 cacggtactg ttcagacatc tcttttcctc actttcatcc tttctcgggt aaaccccgac
    28621 cccgtgtgtc atacgggaaa tttcttaaag tccttgttcg gtctttgcga gctcaggcat
    28681 tgtggtcaca atacccaaaa aatcatatcg ccagctaacc aaaaccttcc agttttgaca
    28741 gctaaccata agataacttg gtggctacgc ccccaaactc ccaggtaaaa ttcttagttg
    28801 gatttttaaa agttgagaaa agtatagcag aagaaagttg gggaagttat cacaaatcaa
    28861 gtagggacta atctctaaca ccactgcatg taccgtccta tatttatgat cagctcccat
    28921 cgtttacatt tttaggtcac tgtcttttca taccaggaat tagaattgac aaatttaatt
    28981 agagaggtat tcatttaatt gttcacttct tcgctccatt tccattacag aaatttcttc
    29041 aatactatgt gttcagctga ctcccatgat tcgttgtact acgtcctaaa cgctcacgga
    29101 ataagccgta catctttcct agtttactct cgtaatttac gtatataggt tacgacacct
    29161 atttggattt tagagttcct catccgctat atatggcttc aagtcacgat tctgtttgta
    29221 gaaccttgat ttcgctaatt ccttcctatc ccccctacat cacgatattc aggcttagga
    29281 gtcgctattg gtttcatctg cagcaaatat ccacagagga cttggacctc agatgtacac
    29341 tatgcctgtc gaacaaagaa aaaagtaggc taaatttcta acctactttt tctgactcta
    29401 ctctgataaa gccgtctcat atatagacat tttatgcttg aaggaatctt ttcctccctc
    29461 taattgattg atgatatgat tttttatata tttttcacta acatatccct gtgattcaat
    29521 ccatccgtta actccatctg actccataat aacaacttga tctgtcatag aatttgttac
    29581 aattgtagca ttatgtgttg ctaaaataat ttgacgttga gctttcacat ctctaaactg
    29641 ctgaactaaa tgcctgtaaa tataacgatt gtctagattg tcttcaggct gatcaataat
    29701 caatggtctg aagtctttag aatagtcact atatgctaat aaaaaatcaa gcatggctac
    29761 aactttttgt cccaaactta atacaccaac ttctttatag agaatatcaa gttgttgcga
    29821 agattctttc gagttaatat taaactccaa aaatcgtgta ttttctttag aaaaaatttt
    29881 tcgtttatat gcacctgata agtgagaacc ttttttcaaa atgtcataac tattgaaatg
    29941 agcaatatag ttaactattt tttgattatt gaaatccttc attatagtca gtgaatgttg
    30001 ataacttcca tctttcttac ttataatatt ttcacttaac cattgattaa cccatgattc
    30061 ttgttcataa tcatatatac atacaatatg caatttatct gctgcactaa tttctactcc
    30121 atgtaaaata tgaggatgta tatcataaat cggataattt ttcattatga ttgagactgc
    30181 catttgtaac tttttaatac ctttggtagt attatgatca gttactacaa ctatttctat
    30241 tccatttttt atgattgcct ctgctaacat aagaaaacta atatattctt ttgaactaga
    30301 aaaaacaacc ttatcaaaat tactaaaaaa aattgtctta tcaactttta ttttcttatt
    30361 ttcaaaaaat atatcatata gttcatcttc agtaattttt ctatatttcg ttgcagtcca
    30421 attagaaaat agcttgtaat cataagaaac aggtgtatgc aaatgaatta aagtcttgtg
    30481 aaagctaccg aatttctctt tggaatttgt tagttcttga taaacagact ttatcttgtt
    30541 attaaaccct ctcatttcta ctctcctaaa aatatcaatt gtttattttt caagtaattc
    30601 attaagtctc ttttccccta ccctcaacat ctccttttct acctgactcc actctccaaa
    30661 caataactca tgaagaacat ctgctgctga agttgtattt tcttttgaat catatacaca
    30721 acttctatct cgttggtaaa tttgaattct ttcaaaaata gctagttctt ccaattgtcg
    30781 tgtattatca actagatgat ttacaatgaa atcatgatgt tcttttggtg ttgcgcgtgc
    30841 ttgatttgga ttgatagcgt acagttcttc gtatcgaata agagtgctca gataggacag
    30901 cttaggcttt gtcgcaatca aggctaattg tacttcatat cccttatttt tcaagagttg
    30961 tgccgttttc tttggaacat caactgttcg taaagttccc tctatcaaaa gattgtatct
    31021 caaactactc aattttgtta ctaaagactc taccattttt cctgcaaaat ctttggtata
    31081 ttctacactg tctttgccat attcttgctg cagttctaaa tagtgtggat gctgagaacg
    31141 aaaactatca ccatctatga taacaatatt tccttgaaat tctttctgtt taatacgatg
    31201 aattgtagtc ttaccggcac cactttgacc tccaagcaaa atcgctatag gttgtttact
    31261 ggactttttt cctcttgtca gtgaacgaag attccttgct aaagcatgtt tgaattcact
    31321 atcagtataa tcttggattt ccattaagct accatccgct tttcagatat ctctaacata
    31381 cgttcaattc catccaaata gccactatat ctctctattt catcaaaagt ttctactaaa
    31441 tagatattcg tatgaatcaa gtcagataga tcatcactca ttaaaatcca aggattagat
    31501 tcatcatcaa tgctaattcc ctgactatct tgataacgat agagtcgaga taatagatta
    31561 gcacctcttt ctttcacaat ttcaattttc aaagtcaatt cataatcttc aacaggattg
    31621 agcattttat cttctcctac aatatcgaca taagatacat taaacttctg acaaatgatg
    31681 tcaattaatt ccgtagagac tgaactcgtt ccattttcat aacgactcaa gctatttcga
    31741 gaaattccta taattcgtgc aaattcgggt tgtgttaagt catgtgtttt acgtaaggat
    31801 tttatgttct ttccaatcat agcaaactcc tttattttta taaatccatt atagcataaa
    31861 aaagcataat acaccaattt tggtgcgtta tttcttgttt ttctatccta aactttactt
    31921 ctataaaagt cacctaaaga gccataaata tttattcttg tattaatttt ttcgatgcgc
    31981 aaacgatatc tacaaataca tctataacga ttcacctttt aggattttta ttgtcaaaat
    32041 tgcctttatc tacaaagaca aaatgcttat aaaatagctt gaaatcaagg attatcacct
    32101 ttttcgttgt agcaacactc cacatgtgat tattaggcta ttagcaaagc gtatccaata
    32161 cctcaataaa gtgttgtttt tactgatatt ttaactatat tgtatagtct actatttaaa
    32221 tctcaattag gatattttat agaataccca aaattcaaca ataactaaaa gtaagattcc
    32281 attgtatttc cttgttggtc tttcatatca cgaattttat ttttcagaat attaaagtta
    32341 caaatttcat ctctaatatc gttatccgct ctgtagccat taatcatctc agtcagagtt
    32401 ttccctttac taccattctt tatagtagta tttactcttt ttatactgct ttcaaaaggc
    32461 tcatatgttt tatacttaat tacttcgtct ttaaaattaa ataaaggtgt atccggctta
    32521 gcattccata aaataatcaa ccacattata gcattataaa gctgctttgc agtttcattc
    32581 cacttttcag gttgtaaatt tccactccct gtattgtcat attcttgtct attatttaca
    32641 tgagaatcac ctacaagtgg attaaaaaga ggtagccctt tgtgattaat tagttctaaa
    32701 aaatcccttg ccgcacccat gcaacactga ataacttcct tcttgccatc aattttactc
    32761 tcagcgataa atacataata ttcatcttca atagttgctc ctgcatcact atgtttttgt
    32821 tgatttgcta acagcttaat atgtgcttta ggctaaactt caaaatctct aacaattctt
    32881 tgtcttgttt catgtcctct acaattcatt taagttctcc tttacaagtt tagtaactag
    32941 ccttattata ctatataaga tatgaaatgt accataatct tcatcaacta gtttttagaa
    33001 aatcacaaat ccatctggag agatgacaag ctgattctcc aattcttggc aattgcttgc
    33061 tagtgctact gcttctttct ctaaaagata atcttctgtt gattggttga atattgcttt
    33121 gaggatccgt ccttcgtatt tccattccag agctactaaa tcagatttga tttcttgaag
    33181 gctatacttg ccatgcgaaa taattactga cgcgtatttc cgaatcttaa tcagcctctt
    33241 cataaagttc agcatatcat tgtcacttga tacacgttcc caaggcatac aacgacgaca
    33301 atctggatct ggtcctccag tcaaggctag ctcggttccg taataaatgc acggtgttcc
    33361 tttttgtaaa aagagaaagg ctaaggctga tttaaccagt tgaacatctt cattggccgt
    33421 ccacaggatt cgctctgtat catgtgaatc caagagatta aacatgacct ctgaaatctg
    33481 ctgcttgtaa tacatagact ctccattgat ttcatcgatg aactggtctg tcttcttaat
    33541 tcctcgtaag aaatagtcct tgatactatc agataaagga taattcatga tggcatggaa
    33601 ctcatctcca tttagccaag gctgagatgt atgccagact tctcctagga tataaagatc
    33661 aggattttta gctaaaactg ccttacgaaa atccttccag aactgatggt caatctcatt
    33721 agccacatcc aaacgccaag catcgatatt aaactcttca atccaataag tcgcaacctt
    33781 taaaagataa ttcttgacct ctggattggc tgtatttagc ttaggcatat agtcctcgaa
    33841 accaaaaaca tgatagggta agtctctctt attaactagt ttttcagttg tcactgggaa
    33901 ttgttgaata tggaaccaat ccttataagc agactgttca ccatttttga cgacattttt
    33961 ccattgaaga gattgcgaac caatatgatt aaataccgca tccagcatga ctttcatgcc
    34021 acgatgatgc gcttgatcca ccagttcccg aaaggtctcc ttgtctccaa aatgacggtc
    34081 aatttcaaag taatctgtcg tattgtactt gtgattgctt gtagattcaa agatgggaca
    34141 aagatatagt ccagtaatac ccaagtcttg caagtaatcc atatgatcaa taatcccctg
    34201 taaatcacca ccaaagaaat catcgctctt aggtgtgaca gatgaatccc agtctaaagt
    34261 cccttctggg tttaatagag cattgccatt ggcaaatctt tcaggaaata tctgatacca
    34321 taccgtattt gaaacccagt caggaacctt gcaggcatca atcttgaaga taaggcaact
    34381 taaatccatt cccaattgca tgaagatttt ctagagaatt ttccacacac cctttatcgc
    34441 catacaaaat attttgacct tctgtatctc tgagctcaaa gagatactgg atacgtgcaa
    34501 agtcaactga cacttcaacc tgccaatggt caaataaggt accagaagtt atcttgacca
    34561 tttcttttgt atcctgataa aactcctcca taaagataaa agggtcccca tagtgcaagt
    34621 tgatgctttc aatgtcccct ttcttagttc gaattcgaat atggagtttc ttatccttat
    34681 aaagataggc atactccgac tcaggcctat ggtaaatagc actcaattcc atcaatttgt
    34741 ctcctaaagt attcattcaa attttacgca aacgttttca aactcaatga atccagtata
    34801 ctatttttgt aaactatttg caaggaatgt ccgttgttaa aggaactatc ttttaaagta
    34861 tacaaaaagc cttaaaaaag gctttctcta tatactaatc ctctttcggt tttgaaaata
    34921 cttctactcg ctgagctagg actttgattt ctacaggtag gttatctgat ttatctccgt
    34981 caacatctga ctccaattca ctatctgaag agattttaat attacgcgct ttgatatact
    35041 cgatattatc atttgcgaca acatcccctt ttaataaatc aggaatgacg gataatttgg
    35101 agaatataga ggcatctttc agaatcaaaa tgttggcata gccgtccttg ttttcttcaa
    35161 agattttctt atcagcgaag taatttgtca aaaggaccaa aacatggcta gcttcaccaa
    35221 cataatttcc attttctgtc tcaaccttaa tgttaaagac ctgatctgtc atgacagact
    35281 tcatggtatt tacagcatag gttaaaatac cgaattttgt tttgtcctct atttcaacat
    35341 tgtgaatcgc ctcaggcaga gaaccgatac taaagatata accaaaatag ttgtcatttg
    35401 ctttaccgat atcaatctta ttgattaaat caaaatccag ttcgtcaatt gcgccatcga
    35461 tgtcttgatt gatttccaaa agttttgtaa tgaggttacc cgtaccgcct gggataatcc
    35521 ctaacttagg aatgtagtct ctctcatcaa tacctgaaat gacttcattg acagttccat
    35581 ctccaccaaa cacaaccact gcatcatact gctcacgaga agcttcttca gcaaaatgtg
    35641 ttgcatccag cgctttttcg gtaattttgg tttcaacata ttcaaagtat tcttttgctt
    35701 tattctccag cttttctttg taatccaaag ccttctcgcc accagaagta gggttgataa
    35761 ttaccattgc ttttttcatt gattttatcc ttaattttaa acagaaatgt ttacatttcg
    35821 tcgtatgcaa gtaaatgtaa tcctattata caatgaaaat acagaaaaga gaaatctgac
    35881 atactggaga ttaatacgct tttattctat tttcccatcg cctaactaca tcctttaagg
    35941 gttcatccaa gtaagaatag gccttatcct tgatccaatc aggaataccg taagctgcct
    36001 ctgctatgct acaagtgatt gctgcgagag tatcactgtc gccaccaagt gagatggcat
    36061 ttcttatcgc atcttcgaag tctctacttt caagaaaggc gataatggct tgagggacag
    36121 tttcctgaca tgtttcgtta aaacgatagt taggacggat ttcatctaaa gtttgagata
    36181 gattgtaatc gtattctttt tctatataat ccttaattcg tcttttacac tctgtaggat
    36241 tgtcgttaat tgattgctcg tactctctac aataaccacc aaagtaaaaa cgacatagaa
    36301 agatagcatc agctgtagcc atagcgcctt tgacaccttc tggatgatta tgagttacct
    36361 ctgcagaaag actcgtaagt cctctagatg atggccacat accagttttc gcataaaaac
    36421 cacagtccat gatccaagca catggagaaa tacgcatagc tgatccattc ccaaagctat
    36481 tataaggctc acggttatcg ctgtttagcc atgcattaaa ccgagcaccg taatcagcat
    36541 tcggatacat tctgccatat ttcttcatcg cgtcaatgaa atcgtctttt tgtccaccat
    36601 tcataattgc ttctgcaaca gcacaggtca taaccgtgtc atctgtaaaa aagcagtcct
    36661 tccgaaataa aggaaagtcc tttgttttga tattgttcca ttcgtaaaca gaaccgacaa
    36721 tatctccaat aattgctcca agcatcagat tcctccttgt tcattttgat gctttttata
    36781 ttggttatct accatattta ttttagaaaa taacatcctg ttggatttta aaaatttcat
    36841 ttttttcaaa atagggtttt accatttctt tccacctagc tctatgaaaa ttgattgatt
    36901 ttaaaggaga taggccataa tttcccaatg cataaccatc atttacttca acaacaagtg
    36961 ttctgccatc gcgagtaaca ccgatatcta gtccataagc tattggcgca tctttccaac
    37021 atgatatcgc ttcatcaatt acacttgcat caaattgtgc atgataatca cctgtatagg
    37081 gtcgaacatc taatacgcga ccatctaaca caaaacaacg ccattcagct atgaattcta
    37141 caacctcact aatccatata ggatagtcga aaggtagacc aatacctatt aaatcatggg
    37201 ttccattaac aactcttcca gtaaagactt ttgaaccagc tttaggctta ataaattttc
    37261 cccaattatc aggtatattc acaatctctc ctaaaatacc agcataaatc tttcgaccat
    37321 aaaactcttt aagctcaata ggatagtcat gaaccggaac gtttaagccc atcattttta
    37381 gtaatgctct agtctccatt atataatcta caactatatc ttcacttgtt aactctttta
    37441 tttcagaaaa agattgatat aaaataactt cttctccttg taagtaggca cctacttgag
    37501 cattgtattt attaattgaa acctcacttg gtaatttact ttgtctaata taaacaacca
    37561 tttcatcact cctatatcac tagtgttaca ccaatttgta aaaaataata gcaattttgc
    37621 tcttattttt ttgagtaaat agcccccata atatcatcga aataatcaac ggtatttagg
    37681 agtaattcaa taacctggga ctttgttagt cgcattcccc ttctatctct agcatcttct
    37741 actaaatttt caagtttctc tagattttta tcatccaagc taatcattat tctattttta
    37801 tcggttgcca ttttcatcac ctcgagttaa ttctatcaca ggtgtaacac ttgtgtcaac
    37861 tggcttttat aatacattag tttaaaagtg gagaggattt ttaacacagt aactttaaat
    37921 ctttggtatt aaaaaatttt cacaatattt atagaaataa aatctgtctc aaatcagtta
    37981 tcaaatctag tataaattat gagcggctac tctaatactt tccctctaaa caagaaaaag
    38041 acttacactc aagggttttc ttcccccccc ttcgttataa cgttttgact cttttactag
    38101 caaaggtata tactcacaag gaactttggt tgactattga atctctccaa cttcttcttt
    38161 aacatatcct tctacatctt caatctctac aaacattggg tctaagtgac acaagaaatg
    38221 ccaaacttcg atcccttttt ttctgtaaag aatcgcttca ccgtcttcac ttccgaaaaa
    38281 gcttctgtcg atttcatatc cgcggctttc taagaagtct tttgctttac gatagttcgt
    38341 ttctcttgtt tcgacatagg ctttaacttc atggttgtta acgacatatg catcaatttt
    38401 tgaatatcct tcgatcactc tatcattttt gagggataaa tttgaaatct ctttccaaat
    38461 aatgtttaca ttttcctcag gatcgaacat aaatttagat aaaggaacaa tatttccgtt
    38521 aaaaataatt tccatataat ccggtatgtt tttaggatta aaatactcca cttcaaaacc
    38581 atcttctgtt tccagagtgt atcccgggat ttgagctaca aaggctttcc catcttctat
    38641 ggaatcaaat gctactaaat ctttagaata atcattttgg tacaattcca atataaccat
    38701 cgataatctc tccattttca ttatcaggct aatgtaaata agcacgtcac ctgaccaatt
    38761 caggctctct gtatcatctc atcatatttc ctacttactt tacgagtcct atacccagaa
    38821 cacaccttat cgaccttcgg tctcacctcg tcgcattggc tgaacatcta cttttacttc
    38881 gctgatgctt caactcgtac aagcagtgat accgcctcag cgtgatgcgt cagtgggact
    38941 caaaaagttt ggggaacctt ttgaggatta actacgtttc tctaataaac ttacacattc
    39001 aacttgttca tcattgtcca aatctatgtt gagattttct tctataattg gtagcttaaa
    39061 agtaatggat tttagccatt gtccgttaga ttgtttttct tcataaactt gaatttcaga
    39121 aatcaaagct gaaattaact gcctacgctc tacatcattc atgactttat agagcttatc
    39181 aaaatagatc agaaccttat atatgttatc tcctgtaagc ttttcagctt caatagtctg
    39241 tttctttgct ttcgcatcaa ttagtgatga ttctaattca tctattttgt catacatacg
    39301 atatagtcta tcatctaaat cctgtttcct tctcttataa tgcttatctt caacatctaa
    39361 attatctatt tcctcaatta gcttaaactt tgtagaatga ctctttctca attccttttg
    39421 gtaattatct atttcttttt ctatttcaga ggtatccacc ttcatgttga ttttttcttg
    39481 catcatagaa gcaaatttcg gattacttac tatcttgaca atcacctctg caacagcatc
    39541 atctaacaat tcttctctaa tttgcttact gaatgtacac ttatgacctc ttatcatctg
    39601 cctatggtta caaccatagt aataaaaatc tttatacttt gtgccatctt tctttttctt
    39661 gatacacttg ttcccaaaca ttcccactcc acatatcggg cattttacaa ttccagaaag
    39721 caagtgtgtg cgtgtatctt ttcctttatt cacatgctca tatttctttg cttgagattt
    39781 tagcttaacc tgagcagctt accaaacttc atcggaaact atagcttcat gtatcccttc
    39841 agatattaga tattcatctt gttcaacctg cttatattca tttcttgtac catgaacttt
    39901 ttctaaagtt cttcttccaa atgctatttt cccattatat acaggattct ttaatatctt
    39961 tcttataaga cctgcatcaa acaaaggatt cttaccattc tgtcttggga tttttctaat
    40021 tccatgattc tctaagtatt tagatatccc attggctcct atcgtagtat ttacatactg
    40081 gtcgaaaatc gttcttattg caactgcctc ttcctcattt ataaacagct tgccgtcttc
    40141 aagtttatat ccatacggag caaagccacc attccatttt ccttcccttg ctttttgaat
    40201 gcaaccttcc attgtttgaa tacggatgtt ttctctttct atttcagcca cagctgataa
    40261 aacagaaatc attagtttcc cagcatcttt agatgaatca atgccatctt caacgcagat
    40321 aagattaact ccataatcct gcattatctg aagtgtagaa agaacatcag cggcatttct
    40381 tgcaaatctt gataacttaa acacaagaac aaaagatact ccatcttttc cagattttat
    40441 atcttccatc attcgattga actgtattct accttcaata gacttgccag acttcccggc
    40501 atcttcatac tctccaacaa tttcataatc gttgtaaata gcaaaagctt tcattcgtga
    40561 tttttgtgcc tctaacgaat acccctctat ctgtattgac gtagatactc gtgtatagag
    40621 gtatactttt attttttctt ttgacatagt attaacctca atataatttt tctatatcat
    40681 atataatttt tttaatttaa gtttggacta tcatttcaag tatattataa cacttttatt
    40741 agtccgtctc aatttgtgtt tttgccatgt caaaactatt tttcatctct tgattttttg
    40801 ctggcgttgg atcgggtaga ttatctaaat ctaaagcacc agcatatttt gcaatcagat
    40861 ttgctattaa atcagccaat ccattccagt cattgtccaa tatatacctc ctctaaagtt
    40921 ttatatctaa taattatttg tttaattaag ttttttgaca ttgacaagtg ctttggatta
    40981 gcaacatagg aatctcacct ccgcctctat tccggatgag ccggcttcaa ccttagaagt
    41041 atcattatcc tcattttctt catagcggat agggtatccc tccctatatt caaactctta
    41101 cttatcgctc actttctttt tacttagcag aacttttttt gccgaattat tcagccgaaa
    41161 gatcttgacg gataggttat tacgctccaa aaataattaa cgtcttgtct tggtctattc
    41221 aattgttaag gttcaaaatt tatcgagagt tattaatctt tttaaaattt gaccatcaga
    41281 aaatatttat cttaatgtaa caaaattcta taaattaccc tcttatactt aacagtgaaa
    41341 agaagtcttt cttggtaacc aattttgaaa tagaatttgc ttatataaaa aggtcaaatt
    41401 cccactgcat aagtagcagt gaaaattaga ccctcttggt aactgtcatc taaaagtctt
    41461 ctagcatttc tttaattttc taatcgcctt taaagtgtca tatttatatt tttttatctc
    41521 tggcatactt tgataccttt ttagacttaa agtctttaat agtgcctttc cacctctttt
    41581 tatctataaa gattctccta catcataatt cattttttta tttaaacctt tctgtcttag
    41641 tttgtcttta tcttcttcat accattttaa gattgtcaca tagtggtttt gataggtctt
    41701 accactgctt tccatgtatc tggatagttt atttatcatt atatctgtgt gtgagtttaa
    41761 tttttctttt agatttttat attcttcttt gcttaacctt acatttttga attctccata
    41821 aaaaatgggg gtggactttt tatctatctc tccctctctc tctttatcta tctctatatc
    41881 tttccatgta attccaatct ggagtacctc tactgtctat cggtaattta attttgatat
    41941 ctggcaatac tgtgctagat atttgatctt tatattcagt attttttaaa gcttgcctaa
    42001 taattgaagt taaatagaat gctacttctt tattcaattc tttatttttt aattttaaac
    42061 aatgaatttt catatctagg cttgctttat atttatgata aaagactgct cctaaaaatg
    42121 aaacagatat aaaattttca aaaactctat aatttttatc atctatatct tcgtagtaac
    42181 ctaagatacc attgtcaata tttgtagcac taattctagg agtttttcca tcgagtaaat
    42241 atctttttgg aatagatgag cctgttggta cttgactcga tttccccttt ttttcggtaa
    42301 taaatatttc tttttatttt gttgtccgat atttttccta cctgtccttt gtaggatgag
    42361 tattttctag attttcttga ataacttttt acttgaagtt ttagcttttg aactagtcgt
    42421 tgtactttct ttttgtttat tatcagtcct gatcttttta atattgctgt tattctctat
    42481 atcctatttt tcattcatga tattctttta ctaattttat cttaaattct gtgctgtatt
    42541 tgccattaaa aaactgacct cctttagtta gttttttggc ctaacttttg agggtcagtt
    42601 caaaatttgc gacttttaaa tgaattccga tattcaatta ttaagagcta acatggtgct
    42661 tgccaatagg aatcattaga ggcgaattgg aaatagggtc acgtataatt tttgcttcaa
    42721 gattaaagat atctttaact agtttatcat ttagtatatc ttcaggcttt ccctctgcaa
    42781 caagtttacc ttctttaatt gcaaataggt aatcagcgta tcttgctgtt agatttatat
    42841 cgtgcaaaat catgcaaatg gttgtcttat atttttggtt tagatcagtc aagaggtcta
    42901 atagttctat ttgatatgag atatccaagt aagtagttgg ctcatctaaa agtaggatac
    42961 ttgtatcttg ggctagggct agagctatcc atactctttg cctttgaccc ccagaaagtt
    43021 cttcaactag gttatttgct agatcttcaa cattggcctt aaccattgat ctgtttatta
    43081 tttcaaggtc atcttttcca agactcttaa aaggctttct gtaggggaaa cgaccacggc
    43141 ttacaagatc agctactgtt attgattcag ggattattgg agattgaggt aatatagcta
    43201 tgtgttttgc taaatctttt tctttataag aattaattga tttattatcg agcaatactt
    43261 ctccctctaa tggctttata agtcgagaca aggttttaat gagtgttgat ttcccacaac
    43321 catttgaccc aataataact gatatttttt cttcaggtat ttttatattt atattttcca
    43381 agattatttt ttcatcataa ccgcaggtaa gattatttga ccacagacct ttcattatat
    43441 attcctcctg ttcattttta ttagtaagta tattaagtat ggtgaaccta acaagccagt
    43501 tacaacacct actggatatc tagctggtaa aatattttga gagaatatgt ctgataacaa
    43561 aactagtaaa attccaacca atccagctaa tattgggctt cttttcttgc caatatttaa
    43621 ggctatggga ccagctaaaa aagatataca agctattggt cctgtaattg aagtagaaaa
    43681 agcagttaaa gatacagcgc aaaaaattaa aacaagcctt gaaagctcgg gatttgctcc
    43741 aagtccgatt gctatttctt caccaagttc aataatttct agtcttttat taaaaaataa
    43801 aactaatata gtagcaataa tacttactat tagaacaaga ggtatgtcat ctaactttgt
    43861 aaaagataaa gagccactga gccatctcat aacttcttgt aattcatatc ttgctacttt
    43921 caacaataaa aatgaggtgc ctgctcttgt gacagcttga aaaccaatgc ctaatattat
    43981 cagtcttgct gctgaaaaac catctttttt agctagtaaa aataatatta aagatgatgt
    44041 tagtccacaa gttattgaaa taattccagt agttaaacta tttgttttta ataccaatat
    44101 gcaaaagacc gctgcaatag atgaagaact tgtgacaccg attatatcag gacttgcaag
    44161 aggatttctt aacatagttt gaaagataaa tcctgccaat ccaaaagacc agccagctat
    44221 aattcctgct aataattttg gtaatctaat ttccataatc gaaaaactag ctccaggaac
    44281 agtttcacta tttaagactt taatcaaagt tgaaaaagaa taactttcat ctccgataag
    44341 taaaatgaaa aatgatagac tgattattat taataaaaat agtgaggaaa atagtgttat
    44401 tctatttttt cttttttgaa tacctataat taaattttgc attagttatt aacccctcta
    44461 tttttcatag ttacataaat aagtactgga cccccgatta ttgcagtaat tatccctact
    44521 tcaatttcac ctggtttacc taacatacgg ccgattatat cacatataag caagagctct
    44581 gcacctataa aagatgaaga aatggtcatt gtgcgtatat ctttgcttat aaataagcca
    44641 caaaagtgag gaactataag acctacgaag ccaataggtc caccaattgc agtaatactt
    44701 gaacataaaa gcacacttgc aattattgca agtgatctta tcctattaac attaactcca
    44761 agaccaacag ccatttcatc acccatagct aaagcgttta aatctgatga aataaatata
    44821 gctatcaaat gacctaaaat tataaaaggt agtagtgtag atatagaaga taatgtagct
    44881 gctccaaggc tacctatttg ccaaaatcta aatttgtcta agacgttatt attcggtaaa
    44941 attaaaaaac ttacaaaact gcttaaagcc atactaacac aagttcctga taaggcaagt
    45001 tttatagggg taaggcctgc ttttccgctt acagcaatcg cgtatacaaa aattgcactt
    45061 actaagccac caatgattgc aaaacttata tggcttatgc ttgatgaaat tcctaaaaaa
    45121 gaaagaccaa ttactacact aagacttgct cctgtgttta taccgagtat acctggatca
    45181 gctattgggt ttctagtaac tgattgcatc aatacaccgc ttatggcaag actagaacct
    45241 gctaaaattg caaaaatagt tctaggtatt cttttatata taattgattt aataaaatca
    45301 tcatttgtat tacccattcc aaaagctgct aaaaaatctc tgatattaat ttcttttgtt
    45361 ccaagcttta atgacaaaaa tattgtaata agaagaccta ggcagattac aaaaattatg
    45421 cctaggttta tttgtttttt atttcgcatt tttgcatgca tttcctaaaa gatttaggta
    45481 ttcttcaata gtatagttta ttgaaagtgg tgttggagtg catgaggctg ctaacggtgt
    45541 attatctgga attacagcaa cggcaccatt tttaattgca tttattttac ctaaaagagg
    45601 atctttttgt aaagcttcaa gagttttatc atcaccataa gttatgatta catcagcatc
    45661 atttatctta tttgcttctt ctgcagaaat ttcctttgca aaactatctt cactctcaaa
    45721 ttcttttaat gattcaggga aaactagacc taaatctgtt aaataatttg ctcttggatc
    45781 tttgctagta taaatccaga attttgatgt atctgcagca ttaatcatag taaataatac
    45841 tttttttcct ttgatttttc ctttgatttc tggatgtttt tctaattctt tggatatacg
    45901 agcttcagta tttttgatta actcatcacc ttctttttcc atacctaagg cttttgaatc
    45961 aattttaatc atatctctcc ataaagtttg ccaaggttta gatttgtatg ctgctacagg
    46021 agcaattttt gatagagtgt cataatcttc tttagttata ccagaataac ctgctaagat
    46081 aacatctggt ttagaatttg atattgcttc aaagttaagt ccatccaaat cgtcaaatag
    46141 gttagcttta ccatttagtt ctttgatttt ttcttctgtc catggtaaaa ctcctttatc
    46201 agcacttaca ccgtaatttg cttttgaaaa tccaacagga actattccta aagctaatgc
    46261 tacatcatga tttccccaag caatagttgc aactctttca ggttttttat ctaatatagt
    46321 ttgaccgaaa gcatgatcta aaactatttt atcaggcgca tgctctttag aagtattttc
    46381 ttcattttta acagaattag aagaacaagc gctaaaaact atacacatag ctaaaatagc
    46441 tattagaaaa aatttgtttt tcataaaaac tccttaaaca tatttcaagt ctattgtatc
    46501 gataataatt atcattgtca atagatacag ttacaaattt aataatataa ttttttcaaa
    46561 aaaggatcta gtttttattt ttagttaaat tatgtctata tttttcatta actcatcaat
    46621 aaaaatttgt ttgctaatat ctctttcttc tgattttgtt tcaaggatta ttgctacatc
    46681 attcatattt ttaggtaaat accaaccatc tggcttatct gaatatccct tgaagcctaa
    46741 ttgattaaaa gtagttattt gaccagtacc ttgattgatg ttttcttcaa cttcattaaa
    46801 gcctatactt ctcttgcata atccctaact tgatcttctg tccttaaagt cattttctat
    46861 tcctcgtcac taaaattatc ttcaaaacta ataatatcat taggagtgca agataaagcc
    46921 ttacatattc tttctaaatt cttaaatgta attggtttat cctttcccat ttgtgccata
    46981 acatttgttg taagtcctgc catagctatt acatctgttt tctttagtcc tttttttgct
    47041 aactgtatcc ataatggttt atagttaagt gccataatat ccctcttttt ttcttcatta
    47101 gatttattta attatagcat aaatattgat tttattcaat cttacattga tttagtgatt
    47161 tgttttagag aatttgttgt gttattccgt ccttattttg ccataaattg ttttaagtgg
    47221 gacctcttat ccttaccatt tttacctcct aattttgagt ataaaaaaga cgatagagtt
    47281 tttaatttct atcgtctgag atttacatat taaattttca tcacaaaata agactcttta
    47341 aagaatcttt aaattcattg gtatgctgct tacaatatcc attattaaaa tggatattgt
    47401 aagcagcata ccaactattt attttttgag ttttaaactt tggtagaagt cttgaactcc
    47461 ttatatttac ataactattt gcctctataa ctgttatgac acgaaaccaa caagcaagtt
    47521 caagcacctc catatcttta ttcaaatgag gactaagata ttcacaaact ttatcataaa
    47581 cctctttatc ttttttcata aaaggggcat acaacttagc aaatttatcc taaaattttt
    47641 tgttgccttt atcaatcatt tcaacgctcc tttaaatata aaaatgatcc tatcaatctt
    47701 tatattgagc ctattttcta attgatacct tgcaagaaag gaataatagc tgttcctata
    47761 ccaagtagga atgtaataaa tgcagaaagt catatactgt cattcttttc tattaaatca
    47821 ttttgaagtg tctcaaagca tccatgatgg cttcttcttt ttcaggtgta cactgtggaa
    47881 taatttgttt atccttttta gacttgttgt aatgttctcg taattctatt ccacatttct
    47941 tttttatctg tgcaatatat aatgtcgaaa cttttaattc aaatttattc caaacatatt
    48001 ctttgatttg agcatatgtt gctttgctct ccgcacttgt caaatccatc tcatccagct
    48061 caatttcaac acttatgtgc ttatcgacat caagtttgga caaaagtgct accgtctcga
    48121 cgtgatgcgt ttgaggaaat agatccaccg gctggacttt cttcaattca tatcccaatt
    48181 cttggtagag tttgatatca cgcgccatgg ttgcgacatt gcaggagata taggcgatgc
    48241 gatcggctcc tgtttgggcg cttgctttga taaagctttc tgtcaagccc ttgcgtggag
    48301 gatcaaccaa gataacggtt ggttgaatcc catctttaag ccaattcttc atagcatttt
    48361 cagctgtgtc acagacatag tgggcgtttg aaatattgtt cagctgagca ttttttttac
    48421 tattctcaac cgcttctgga atcagttcaa caccgtagac ttctttgaca tgcttggcga
    48481 ctgataaacc aatggttcca ataccagaat aagcatcaat aaccacgtca tcttttttta
    48541 actctgcaaa gtcaatggct gtttgataga gtttctccgc catttcagta ttgacttggt
    48601 aaaaggctgg gccagcgatt tggaagtcat ttcccaacat ctggtccgta atatagtctt
    48661 gaccataaag agtgcgccac tccttaccaa aaatcgcatt ggtattctgg tcgttgatat
    48721 tttgcatgac agacacaatc tctgggaact gcttgataac ttgttcaatc aattggtcaa
    48781 cacgaaaaac ttttggacga gttgtcacca aaacgaccat gatttgtcct gaatagtgac
    48841 cacgacgcac cacaagattc cgaatcaatc cagactgttc cttttcgtca taaggtttta
    48901 aatcaaaacg acggagcagg tctcgaagag ctactacgac ttggtcaatg acaggatcct
    48961 ggataaagaa atcttcaagg ggcatgaggt cgtgcgaatt cttacggaaa aatcctgttt
    49021 ccaagacacc attcactcga cgaacgggca cctgcgcctt attgcgatac ttgactggat
    49081 gttccatacc aagcgtttca gcaacttcta catctgcaat tccagcaatc ttgtagagac
    49141 tgtccttgac ttgcttggtt ttaaacttga gctgttctgg ataagaaagg tgtcctaaat
    49201 ccgcgattcc tgaacgcagg taagccaaat ctagatcttg attacggtgt ggtgactgga
    49261 caaggtattt ttcaactttt ccaaagccaa tctttttatt gaccttgagg acacgcatga
    49321 gaattttttc actcggtaaa gcattctcta caaaaaagac caaaccatct accttggcaa
    49381 ctcctgcccc ttcatgggtc aagtcaacaa tttcaacttc tacaatatca tttttcttta
    49441 acattctttt ctctttctat tggccgacaa aaaagacggt aacgttacgg ttaccatcca
    49501 ttataccatg aaatttctta agaaccaaaa ctcttgaaga agttgacaag ggcttgccag
    49561 agggagctta agaagttacc accgtcctct agcgccttat ccgcatcaaa gttaaggttg
    49621 atatttttaa aactgtcgcc agcttgtgat acgatgcttt gtttaaggtc atttagggtt
    49681 ttagtgaaat ctgcattgct gaggatatca ctctttgaga gattcaaggc aaaattgatg
    49741 atgatattga tctggtttcc tgttatgacc tgatcaagtt tgtaattttt taaggtatct
    49801 tcaacaatct tgcggatatc ttcttctgtc agatttccct tgctttcttt agctttggcg
    49861 agtcctgact tgatatcagc tagggcaacg tttaatttat tagcatcata gcctgatttg
    49921 tccttgtttt cagcattgat atctgacaaa gcttttagct cttcttgagc caaatcttta
    49981 ttagcttgtg gcaccttggc tccattagcc tctagcgaat agtaaatccc tgctaaagca
    50041 ctttctcctg taactggaat aggggctgct acagtgattt tggcatgttc catacccagc
    50101 gttactgctg cgtttcggta catatcctga gtcaccttag tgatattttc tggtgtttca
    50161 atcttgacct caagtggcga tttgtcacct agcttttgaa tcttggctga tgaatacaac
    50221 tgtaagctag agtcattggc cacattcatg attttagaat aaacatcagg tgtcatggtc
    50281 ttgagttctt tggtatctgt tgaggcattg tagcccagtt ttttaagagt ttgatttttt
    50341 tggtcttcag atagggagga acctaggaca tattcaggtt ggacataggt ttcatcgata
    50401 actttttgaa catctgttgc tgcatggacg ctattcatag ctgttactgc ccacaagacc
    50461 gcagcactag tcagaaagag tttctttctc atagggaatt tcctccttta cttctttata
    50521 gtaatatatc tatcttaaag aaaacttata acaaaaacac ctggtctagc cagatgttga
    50581 aaagagagtg aaacatttga tgatgtaaag gttaagtcgt acctgtctag aataataata
    50641 atttcctcca tttacataga gttcagcacc gtgaaaaatg gaaatggggt gaatataact
    50701 ataagtcttt ccagtcgtat taccaagcaa gggggcaaca gtctcacgag agtactgttt
    50761 ggctagagcc aaggtatttt ccttgccatt ttgggcgata aaatcgatat aggcaggtcc
    50821 aaaattatag gcttgaacag ctgtccagat atctacaccc ttcttctgcg ccagatagag
    50881 attgcctgtc agagtttgaa tgccttgccg aatgctagag gcattatcat tgatggtgtt
    50941 ggtggaacca cttgcagact cactagactg cataacatcg ccttcttttc cttttgtttc
    51001 agtataaatc atagcaagca caagctcttc gtttgctggg gtgtcttttt cactcaagat
    51061 ttctcgcacc atgggttgat aggtcatgac ttgtttgaca tcttgatgaa cgcggtaagc
    51121 tttatagcca gcaaaaagga agactgctag tacaagcact cttcgaattc gtttaaacat
    51181 tatttacttt ggatatcctc gatatttttg attaagatag agtaggttcc attttcgttt
    51241 tggataaact caacagactc ggcgtcttga tagacgttat tgggaacgat gagctcaatt
    51301 ccatttgata aggagagttt ttggttttca aatttcttta attggcgact tgcatcaatt
    51361 tcatcaaatt gaacaggttc tggtacggct tctttgactt ggtcaataaa gctcaaacga
    51421 gccgtcagat tgttgtcaaa aaggtcatta gccaatttct caggtgacaa ttcattgctt
    51481 tcttctaggt tgttgaaaat cgctgatttg accttggatt gaaattgaaa atcatctgtg
    51541 ttaaaagatt cagcaattct ctgggctgtt ttttccagtt ccttgataga ttttttagga
    51601 gaaatcttag gagcgacagc aagaagatta tctgaaaaat agttcaaaaa agtcccgttg
    51661 tacttgattc gtttttcaat caggtgatac ttgcgactct gaagattgac caccaaggcc
    51721 tcgtcagcac ccgttccaaa tccaggcagg ttattctgag tcagcttgat tggattatca
    51781 acttctcctc cgaggtgggt caaggtctcc cgcagggcaa ttcgcaagaa agcgaaatgt
    51841 tctacacctt ctttagaaaa ttgaacaaaa atcaagtcat tggtcttgag attttcagaa
    51901 atgctaaact cctctttcca gagattagcc agcgttactg atgtctccaa caaatcgtct
    51961 gtaatatgat tgaagaaggg attttcttct tcgaaaatcc cagtcttggc ttcatctgaa
    52021 tacacatgtt caattttttt acgtaggtat tcttcgattt ttggagtaat attgagaaac
    52081 ttatctgcta agaacagctc ggtatcatcc ggactgaact ggtgaataat ggctttctta
    52141 atataaatgt ccataaaagt tttattcctc gtataatggg aaggcatctg tcaattcttt
    52201 gactgcactt ctcacttctt ctaatacagc ctcattttct gaattcttaa gggttttaat
    52261 gatgagttca gccactttgc gactttcttc ttcaccaaat ccacgtgcag taatagctgc
    52321 tgctccgata cgaatcccac ttgtcttgaa tggtgacaag gtttcgtaag ggattgaatt
    52381 tttatttagg gtaatattga cttcatccag caagttttga gcaacttttc cgttttctac
    52441 aaccttagtc acatcaacaa ggaagagatg gttttcagtt ccacctgaaa taatacggaa
    52501 atcagggtct tgcaagaaga catctgccat agccttgctg ttcttaatta cattggcagc
    52561 atattccttg aaagctggat ccaaaacttc tttgaaggaa actgccttag cagccacaac
    52621 atgctccaaa ggaccaccct gaataccagg gaaaatagct gaattgattt tcttagctaa
    52681 atcctcatca ttggtcaaaa tcaaaccacc acgaggacca cgaagggttt tgtgggtcgt
    52741 tgttgtagtg atatgagcgt atggcactgg gcttgggtga agaccagctg caaccaagcc
    52801 agcgatgtgg gccatatcaa ccataagctt agccccaaca gcatctgcaa tttcacggaa
    52861 ttttgaaaag tcaataattt gagaataggc tgaagcacca gctacaatca gttttggttt
    52921 tacttcttgg gcttgtttca agatagcatc aaagtccaaa agttccgttt caggatccac
    52981 actataggaa agaaagttgt aggtttgacc agagaagcta actggagctc cgtgggtcaa
    53041 gtgtccacct gctgccaaat ccattcccat aaccgtatca cctggctcaa tcaaggacat
    53101 gtaagccgca cagttagctt ggcttcctga atgtggttgg acattggcaa atttagcacc
    53161 gaaaatttct tttgcgcgtt caatagcaag agtctctaca acgtctacta catcagttcc
    53221 accataataa cggcgtcctg ggtaaccctc ggcatattta tttgtcaaga tagacccttg
    53281 agctgccata acagccttgg aaactacgtt ttccgaagca attaactcga tattattttg
    53341 ttggcgttct tcttctttgg caatagcatt ccagagatca gcatcatatg ctttaaaatc
    53401 atctttgtca aaaatcatag gtcttctcct ttattgtgtg actagtccat tagtttgatt
    53461 ttacaataag aaaatcaaac taaaagatgc gaataaaccg tttctgcatt ttatcacaag
    53521 tatagccaac tttttcataa aatgcatgag cacccagacg atgattggca gaatttaagc
    53581 ggataaaccc ataaccacat cttttggctt cttgttccaa cccttgtagt aaacttttac
    53641 cgataccttg accttgcgct tgaggtgaaa ctgctaaagc taagatatta aatcctgctt
    53701 tggaatagag tgattcgtaa acttcagcgt ggacatatcc aagtaagaca tgattagctg
    53761 catcctcata gccaagtagg aaatgatggg aatcctgaga cagtctagct agttggctag
    53821 ccgtttcctc tggactaaaa gtataaccca aagcctcttg gttgatgtca catatcgctt
    53881 tcacatctgt ttcttgcaaa tctcttagca tttcaagcct cctcaaaaga aatctctggc
    53941 aaccgagcaa gaatatcttc tcgtttaatt gcgccttggc gtaagatttt caccttgtct
    54001 ccagacaaat ccacaatagt tgaatcctgt ccagttagaa aagcatcgtc ttccagaccc
    54061 agaacctctt ggtcaaaatc cttcagaatt tgttcaaagg ttacaccact tgcctgacct
    54121 gagatattgg cagacggccc aatcaaggga cctgtctctc gaattaaatc cagtgtgata
    54181 gggtgactgg gcatccgaaa tccaatagtt gcaaggtcag aatttaccca atagggaact
    54241 cggtcattgg cttcgagaat aatggtcaag ggacctggca aaaaggtctc tacaagtttt
    54301 tgtagataag ctggctgatt cttagaaaag tgcaagatat cctctaaaga ggcaacattg
    54361 agattgagcg ccttgtctct aggacgacgt ttgagctggt aaacatggtc aactgctttt
    54421 tcgtctaagg ccttggcaaa aagaccataa accgtctctg taggcagaat gacagctcca
    54481 ccattttcca actcttgtct aatcctgtcc atcatcaacc acgaccatcc tatcttgacc
    54541 aaattggtcc ttgagtgttc gaactctttt ttcaggaaga tgtttcctaa aaagttcggg
    54601 aacactttga ccttgcttgt atccaatttc aaggtaaatc ttaccaccat ccttgagata
    54661 gtcttttgca tcttccgcaa ttctacagta aatagctagg ccatcctcgt ctgcaaagag
    54721 agctagatga ggctccgaat gcaaaacatt caagcctacc tctgactcat cttcacgaga
    54781 gatatagggt ggattggata caattatatc atatttttca gaaatttctg caaaacaatc
    54841 agatttttta aaaaatatat taagattttg atcgctagca ttctctgatg caagctctaa
    54901 ggcctcttga gaaacatctg ctgctgtcac tgaccaatct ggtctatttt ttgctagagc
    54961 gagagcaata gctccactac ctgttccaat atccagaact gagagattcg tctcaagatt
    55021 ttcagttaga ataagctcca ctaactcctc tgtttctgga cgaggaatca aaacccgttc
    55081 atccaccttt aaatgcattc cataaaaatc tgcctgtcca atgatgtact gagctggctt
    55141 gtgagctgct agttgctggt aaatatcttc tacaaattgt ttttcttcct ctgttgtcac
    55201 ctcctgctgg agggcaaaaa taaagtctgt aaaagataga tttttcagac tacgatagac
    55261 aaaagagagg ctttccgctt cctctccttg tcttatcaac tcttcttcaa aatttgaaaa
    55321 taattgagct aatttcatta tttgtttaat tcttctagtt tttgtgtttg gtcataaagc
    55381 accaaggcat ccacaacttc gtccaattta ccagacaaaa tcgtatctag tttttggagg
    55441 gtcaagccga tacggtggtc tgtgacacgg ttttgtggga agttataagt tcggatccgt
    55501 tctgaacggt caccagtacc gattgtcgac ttacgctcag cgtcttgttc atcctgagca
    55561 atctgagcaa agtggtcagc gacgcgtgca cggataatct tcatagcctt ctcgcggttc
    55621 ttctgctggg tacgttcttc ctgcatctca accttgatat tggttggcaa gtgaacgata
    55681 cgaacggcag tcgcaacctt attgacgttc tgtccaccag caccagaggc gtgatagatg
    55741 tcgacacgaa ggtcttttgg atcaatgtcg tattcaacct cttcaacttc tggcataaca
    55801 agaactgtcg ctgtcgaagt atgaacacgg ccttggcttt ctgtcacagg aacacgttgc
    55861 acacggtggg cacctgattc atacttaagc ttagagtata cagactgacc tgaaaccata
    55921 gcaaccactt ctttaaaacc accgacacca ttcatagagg cttccatgac ttcaaagcgc
    55981 caaccttggg cttccgcata cttttggtac atagttagca aatctccagc gaaaagtgcc
    56041 gcttcgtctc caccagctgc tccacggatt tcaaggatga tattcttgtc atcgtttgga
    56101 tcctttggaa ggagcaaaat tttcagtttt tcttcatatt cttctttttc agccttggca
    56161 tctttgagtt cttgcttggc catttcttcc aagtccgcat ctccgcctga ttccttaatc
    56221 atctcttcgg catcgacgat attttgaagg acttgtttat actcacggta ggctattacg
    56281 gtgtcacgat tggaagcttc ttcttttgaa agctccataa aacgcttggt gtctgaaacg
    56341 acatcagggt cactcagcaa ttctcctagt tcttcataac ggtcttctac agcttgtagt
    56401 tgatcataga tgttcatttt ttctccttat ttctcaattg ttaaatcata gattgctact
    56461 acttcattct cggctatttc cccagtttct ttaaatccat aactgaggta acaaaatctt
    56521 gcctgttcat tttctggttc ataagacaac caaagtttat tgcttaaacc tgctggcgct
    56581 gttcgaacat agtctagtac tttatccata attggtttaa aatatccttg attttgaaaa
    56641 ttcctatcaa tcataaaacg aaatagtaaa taatttccac tactaattcc gatcttttta
    56701 tcataagcta tcatcacaaa acctataatt gcatcattat cataaactgc caatgtagct
    56761 acaaaatctc catttttagt gtagacgtat gcttcagcta aactaattgc gttggttgca
    56821 atgaattgtt tttgatattc cttgacatcc aaatttaaaa catcaaaata attttccatt
    56881 gtaacatctc ttagttcaat tgtcatagtt ttgctccttg ttagaggtta tcattggcgt
    56941 aaaataatgt ttacggcaaa ctgagatata ggtttcgtta ccaccaatct ggatctgttc
    57001 tccatcgtaa acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca
    57061 atactgacag atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga
    57121 accttcgaac aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc
    57181 taactcgtcc acaacacgag ctaggtcgta aacatggtgg cgtttaagaa actgggcttc
    57241 atcgaccaaa acacagtaag gtttttctgg taggtctcgg atatagccaa agatatccgt
    57301 tgtttcctca atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac
    57361 accgtcacgc gtatccagag ccgaggtcat aatgacaaca ccttttcctt gctcctcgta
    57421 gttataggcc actttgagaa tctcaatcgt tttaccagag ttcatggtcc cataacgata
    57481 gtacaactgt gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt
    57541 atatcataat tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac
    57601 tagtggagga agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg
    57661 agcaaaagaa agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc
    57721 ctcaatctgc tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag
    57781 gggaaatgcg tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca
    57841 agtagcattc attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa
    57901 tttccaagaa aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc
    57961 atcgctgcta tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga
    58021 acagacagtt ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc
    58081 agccacactc tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag
    58141 gttatggttg gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt
    58201 aacacccacg gtgggattgc ggtgaccaat gaaattctcc agctagctat tcgtgaaggg
    58261 gctcggttgg cagaacctgg tgaatttacc aaacgtgctt ttttaaacgg tcgcgtagac
    58321 ttgacacagg cagaggctgt gatggatatc atccgtgcca agactgacaa ggccatgaac
    58381 attgcggtca aacaattaga cggctccctt tctgacctca ttaacaatac ccgtcaagaa
    58441 atcctcaata cacttgccca agttgaggtc aatatcgact atcctgaata tgatgatgtt
    58501 gaggaagcta ctactgccgt tgtccgtgag aagactatgg agtttgagca attgctaacc
    58561 aatcttctta gaacagcccg tcgcggcaaa atccttcgtg aaggaatttc aacagctatc
    58621 atcggacgtc ccaacgttgg gaaatccagc cttctcaaca acctcttgcg tgaggacaag
    58681 gctatcgtaa cagatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc
    58741 aatggtgtac ctctcaaatt gattgataca gccggtattc gtgaaacaga tgacatagtg
    58801 gaacaaatcg gtgttgagcg ttcgaaaaaa gccctcaagg aagccgactt ggttctacta
    58861 gtgctaaatg ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa
    58921 gataccaatc gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg
    58981 aaactacctg aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt
    59041 gaagagcgaa tcaacaacct cttctttgaa aatgctggct tggtcgagca agatgctact
    59101 tacttgtcaa acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc
    59161 gttaatcaag gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt
    59221 acttgggaaa tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa
    59281 ctctttagcc aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg
    59341 gattttattg tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg
    59401 cttcgtagtc gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg
    59461 gaacaagagg tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa
    59521 ctggagcagg acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa
    59581 ttgctgcggc tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat
    59641 ccccatttgt atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga
    59701 aagcatctcc atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt
    59761 aagccatatt agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca
    59821 agcgaagcat ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa
    59881 taattggtag gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag
    59941 aaggtttgtt gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta
    60001 cttctttgac aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag
    60061 gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg
    60121 tcaaagttgg actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca
    60181 ataaatgctc aatcaaggct ggaatagcat caaagttaat ggaaccatcc tcatggaagg
    60241 gggtaataaa ggctgtaatg attttacatt cttttaaatc ttgataagac acgaaaacac
    60301 ctctctattt caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca
    60361 aatttcaatt cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga
    60421 actgagttcc aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct
    60481 ttttctgcat ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca
    60541 ttgatagctt gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag
    60601 gctgcgatag ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca
    60661 gactcagagt gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta
    60721 tcatcttcca taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca
    60781 ttatcagtga aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg
    60841 tcaccacctg aaggcaagat ttccgcatgc aaatcacgtg gtttcacacc atcattcaaa
    60901 acctcacgaa gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct
    60961 tgataagttg aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc
    61021 accatcattt ggattgttga acaattaggg caggcaatga ttccgttgtg agcatcaagt
    61081 gcatgagcat tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat
    61141 gtattatcta ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta
    61201 gaactacctg ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct
    61261 tcaattgtaa tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca
    61321 aggtaacgaa ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca
    61381 ccgacagcac ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg
    61441 aattttctaa aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc
    61501 tttttcatca ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat
    61561 cttcatgtga tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc
    61621 ttatgctcaa tagtagtccg aagactacct atcgactcat cgcatattct atattactag
    61681 agatacttga ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta
    61741 ttcaagagtt tccctataca tatcatgcta attgccggga ttgaaccggc gacctcatcc
    61801 ttaccatgga tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat
    61861 tcagaaaaac ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact
    61921 acctagctta tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata
    61981 atcgccccaa taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag
    62041 aatggtaatt ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag
    62101 aggattgaaa agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta
    62161 tattttgcaa aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca
    62221 aagacatcta gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg
    62281 atgatgtact taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga
    62341 taagcaccat agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca
    62401 gcgacgattg caatatctgc aacatcacga atagttaatt ttttcatctt ttctcctttg
    62461 gcggttgccc gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt
    62521 caaccctact agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc
    62581 tattcaaaaa ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac
    62641 tctagtttcg attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc
    62701 tactgcccta gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt
    62761 atttaagcaa aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct
    62821 ttctactttt ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat
    62881 tatagggcaa ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc
    62941 acaaatattc attattatca tcaattatat cttgagcaag gcctatattt ttagaaaata
    63001 atgctccatt tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac
    63061 gaaacattga aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa
    63121 tgttattgac cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc
    63181 acttgtaaac gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt
    63241 tgaacgtatc gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat
    63301 tatcaatttt atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc
    63361 acagaaactg actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga
    63421 agtccttcaa gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg
    63481 caaagctaaa tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt
    63541 tttgatcaga taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac
    63601 aaattctggc atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg
    63661 aactaactca tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt
    63721 gactctaact gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtga
    63781 acgatggtag tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa
    63841 caagacctca atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg
    63901 ttctgtctgt tctctgagat actccaaaac atctggttta atccatggaa taccaatatc
    63961 actctcactc tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac
    64021 tagcttgcta ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat
    64081 gggcacacta tgggctgaaa agatgacttt aaaactgtct tgctttactt cttcttttaa
    64141 aatcttagca atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt
    64201 aatgaccaaa aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta
    64261 gaaagaataa tggggctcca aaatcaagca aatacactgt tcaattccgt ctgcttccat
    64321 ttgaccgatc acatctggaa taaagggact ggaaaactta ttagcaaagt agacactgta
    64381 ttcattcccc agcctagctt ctaccaaggt aacctcttga cgggtaattt tttgcagagg
    64441 cgtgcctcca attcgtacat aattatcata gagagtctga atctcgtggt cttggggtct
    64501 caccccacga cgaatatttg tgaaaaaatc agctacacct tcaaaggtaa tctcttctgg
    64561 tgaaccgaag gtcatcatta aaattgcttt tttcatgact gcttccttgt gatgttttta
    64621 tcaagtttat tttatcatta attcatcgat aagtaaacgc taacataggg acattctcaa
    64681 tcttctgtct tttgtttttc tcttctttct atgatacaat ggaaaaaata aattcaaaag
    64741 gagttttttt atgacttatc caaatctctt ggaccgcttc ttaacctacg ttaaggtcaa
    64801 cacgcgctct gatgaacact ctactactac tccaagtaca cagagtcagg ttgacttcgc
    64861 aacaaatgtc ctaattcctg aaatgaaacg tgttggactg caaaatgttt actatctacc
    64921 gaatggtttt gctattggaa ccttgccagc caacgatccg tctttaacac gtaagattgg
    64981 ttttatatcg cacatggata ctgctgattt taatgctgaa ggagtcaatc cacaggtaat
    65041 tgaaaactac gatggtggtg tgattgaact agggaattct ggtttcaaac tcgatccagc
    65101 tgacttcaag agtcttgaaa aatatccagg acaaacgctc atcacaacag atggaacaac
    65161 cttgctaggt gctgatgaca agtcaggaat tgctgaaatt atgacagcca ttgaatatct
    65221 aactgctcat cctgaaatta agcactgtga gattcgtgtt ggttttggtc cagatgaaga
    65281 aatcggtgtt ggtgccaata aatttgatgc agaagatttt gatgtggatt ttgcctacac
    65341 tgttgatggt ggtccactag gtgaacttca gtacgagact ttctcagccg ctggtgctga
    65401 attgcatttc caaggccgta atgtccaccc tggtactgcc aaagggcaga tggtcaatgc
    65461 ccttcagcta gcaattgatt ttcataatca acttccagaa aatgaccgac ctgagttaac
    65521 tgaaggttac caaggttttt accatctaat ggatgtgaca ggtagtgttg aggaggcgcg
    65581 tgcaagctac atcattcgtg attttgaaaa agatgccttt gaagcgcgta aagcatccat
    65641 gcaatctatc gctgataaga tgaatgcaga acttgggagc taccgtgtca ctctcaactt
    65701 gacagaccag tactacaata tgaaagaagt cattgaaaaa gatatgactc caattaccat
    65761 tgctaaagcc gttatggaag atctaggtat cacgcctatt atcgaaccaa tccggggtgg
    65821 aacagacggc tctaagattt cctttatggg aatcccaact ccgaatatct ttgcaggtgg
    65881 cgaaaatatg cacggacgtt ttgaatacgt tagccttcag actatggaac gtgcagttga
    65941 taccatcatt ggcatcgtag cttataaagg ctaaaaagac gaggtagctc agctacttcg
    66001 cctttctttt tattctactg gtttttcttg atttccagta gttgtagaag attctgttgt
    66061 ttcattttct gaagttgatt cagcaggttt agaatctctt gtattgcttg gtttgttttc
    66121 gtcgctagca atttcaatgt tagattctgc agttgcgttt ggttggttct cagcactggt
    66181 gttatcacta tttgcttcag catttcttgc tggacttgtt tcttcacttg cgctagcttt
    66241 tgactggatt tgatgattca aaactagaat agcttttgtc gattcaagta aagctgtttt
    66301 gtctttactc ttagcagaaa gttgatctaa taatgcatcc accttatcaa agtccgcatc
    66361 agatccatta ttactttcta aataagagtg aagcgacatg agaatatcgt agagtttttg
    66421 atagagtaca agtgtctgag aatcttgctc agcattttcc ttttcttgtt gaagggcgct
    66481 agcgatacga gtcaagacat cttttacctg actgtttact tcatccaagt ctgcatcagc
    66541 cttgtttgtg gcagctttta gattttctac ttcttctgcc aaggattgtc tgattccttc
    66601 ttcatggatt tgttccaaga gttgatttac cttgctcaaa agactttcta cttcttcctt
    66661 gctatctgtc gcagattatt ggttgccatc taccatgtac tcctaaaaca ggagagttat
    66721 aatccaagat tacaaggcct tacagaaata agaaatccag ataagacaat gttcgtccaa
    66781 gacgctattc gcttcgcaca gcagcacgga ttcaatatgc tttaatttta aagtttaggt
    66841 gtcaagacct ctttttagtg tgcccaaaat ttagagaagt aatcaatcaa ctaactttta
    66901 tttttttcaa actttcagta aactgaccta aagctaactc aatctgtctt tgtagatgct
    66961 tctgctatca gctagaagtt gatctacttt tgccaagact gccttctcat caaaagttcc
    67021 aggttgatag ttggattgca gggatggaat cttgtttttc aaagccgctt catatccctt
    67081 agtttgaacc ttgatgtagt gattgtggtc gccatgagga atcacaaaac cttctgaatc
    67141 ttcacttata attcgattgg catcaaaacc atgaccatct tcttcctcat gatggacatg
    67201 tagtgacgga ttacttaata cagaactaga agaacttcct acctcttccg tgttagagtg
    67261 tgatggggga ttgttaagag atgacttagg aatatagtga tagtgatccc catgtcttac
    67321 tatataagca tcacctgtat ctctgacaat atcattaggg ttaaagacat atgtggctgc
    67381 taattcacct gccgacaagt cactctcagg aatgaaatga tagtgaccac catgtggtac
    67441 tatagtagat tgaaatagaa tatgagcaaa ttgataaggg gattttaaag taatttctaa
    67501 caatgattta gaaactatga tgtgctattc taaattcaac tcactatata taaccatcat
    67561 cggtagtata acgtccctgt aattttgcta cagatacttc tgcactagct cctttatcgt
    67621 ctttaccatg ttcttgtttt tggcgattga tttcatcttt tgttcgtaca ttttctgcat
    67681 gagcttgatc tttaaggtaa acataatact ttccatctac cttaataata tatcctccct
    67741 taacctaact gacgatatct tgatctttcg gctgatagtt gggggctttc attaatagct
    67801 cttcactaaa gagcgcatca aaaggaactt taccattata gtagtgataa tgatcgccat
    67861 gagaagttac ataaccttga tctgtaatct taataacaat ttgttttgct tgaattcctt
    67921 ctttttgact aacctagtct ggagtcaaat tttcagtctt cttagtgtct ttattactgt
    67981 ttacatatga aacacgattt ttatctgtat tggcctgtta gctatgttgg ttcagagcat
    68041 aaacacacag acttaaggaa aggataacaa cagatccagc tgctatatat ttctttttaa
    68101 atttcataat tacctcattt ctataattat ttatatgatg tcttcattat taaatgatta
    68161 aataaattaa ttaaccaatt aattaactag taaatattcc acctcttttt aagttgtatg
    68221 tcaagaaatt ttatatatta ataataaaat gaaattctcc caaagtcaga gttttatttc
    68281 taacttttga gagaacttca tttttgattc agactttttc tactgctatt ccttacgcta
    68341 tgagatcaga taaattcttt tttatcactt ctccacttgg caatcttaat tcaatcgttc
    68401 catccatatt gaatataaca ctatctaagc ctaatccgta actagctgta aatttttcta
    68461 atttttcttg tacaggatct actgctggag cttcctctaa tgctggatct aacatagggt
    68521 cactccccac attcccttct ggattcaaca ttccattatc cgttgagttt tctggtttta
    68581 caggtttttc gtttggtgcc tctggtaaag aatctgctgg tttattttct gttggttggt
    68641 tctcaactgt tccagtagat acttttccag tttcagatgg tttattttca ccatttcctt
    68701 gaggtgcttc tcctgtaaaa tctgccatat tctttttaat gacttctccc gatggtaaat
    68761 ataattcaat tgttccgtcc atattaaaca agacattttc tagcttcatc ccataacttt
    68821 cagcaaattt tgctactttt tcttgtacag gatccactgt aggaacttct tctaacgttg
    68881 aatcactagt actgttccca gtttcaggaa gcttttcttt ttctaccttc tcactagtct
    68941 ttggttcttc taccttttca tcaagttttg agttttcttg tgctttattc cttttaaatt
    69001 gtggtagaat acttggttta tcagtttgat tttctttttc caagataggt acttccacaa
    69061 tataagtcga ttgattgtcc aaataagcat ttgccatgaa ggttacagga attttatttc
    69121 cggccgttct ggttgttcct tggtttaatt tcggaatcgg taatttaatt tcaccaactt
    69181 tatagttatt ttctaaataa gcatttccat gaaattcatc aaacactctg actaaagcat
    69241 cagttccttt aggcactgca aattgagggt tcactcttaa ataagtatcc cctgcatgga
    69301 aaggatagaa aatcgtttga ctggccattt tgtaagctaa agaggttgga actgtaaatg
    69361 taccatcata acttacttct ggataatctt ttgaagcgat agtatactta aatgtttgtc
    69421 ctggtaaata aggttgatct aattcaaagt ttgcaatatt ccctactcct tctccaaata
    69481 ctttaccaga tactttctcc aatacttttc catctggtgt tattaatttt actagcatat
    69541 tgatacctaa ttttttttcc aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat
    69601 tggctagagt aaagttttga ttattaaacg tactattttt taacaaatta acaacattcg
    69661 ttaattcttc tccagtataa actttattcc cttctttttt agcaactcct tcttcgggtt
    69721 taaacagttc atagttactg tgagaatgac caattccaac cggtttatgt tcatcaatcg
    69781 gatctgcatg atggtgatct ccatgcggat aaataatcgc atttttttct ttattcacga
    69841 caatactttc acgtttgaca ccatattgtt tcataatgcc agcaattttt tcttcgattt
    69901 ttttatctaa atctttcatt tctttggcat tacctggata atcctgttca tgagatgaca
    69961 aagaatctaa tccattatga ctagttttaa cttcctctaa atgtttttgc gcagccttaa
    70021 tttgctcttc tgtcaagtcc ttcttgaaga aataatgatt gtggtctccg tgactcatga
    70081 caaaacctga ttcatcttca gcgataatac gattagcatc aaatccgtat ccatcttctt
    70141 catgtttctc atgtgaagtt cctggattga ttggaagaga tggagaaggt gttgctagac
    70201 tattgtttgg aagagtcggt tgcccaattt gatttgattt tggaatgtaa tggaaatgat
    70261 caccatgtct tacaatataa gctgtagccg tttcttcaac gatatctttt ggattaaaaa
    70321 tataaccatc agatgctgaa gagagtttct tacttgtcgt taaagaagaa ggattgcttg
    70381 aaagactgcc tagactagac actacttcat taggttttgc atttgtagaa actgtagaac
    70441 cagttccact gataggcacc attctggcaa tcttttcttc taaggcagaa agcttgctgt
    70501 aaggaataaa gtggtaatgg tcgccatgcg gaatcgcaac tccatttggt gtacgactga
    70561 taatcttagc agggtcaaag accaggccat ctgattcact gtaacgttgg gcgctaggtg
    70621 aatcatagag ttccttcaaa agactctgga gattttcaga tttatttgct ggcttgctag
    70681 ttgatccttt tgctacagat tgcgtgttat tgtcactagc tgttgaagaa tagcttaact
    70741 gactcggttg catatttttt ccagccagat gtgctttagc tgctgctaat tcactagcag
    70801 ataaatcgct tttgggaatg tagtgatagt gacctccatg aggaacgata taagcattac
    70861 ccgtatcttc gataatatca gctggattaa agacataacc atcatttgtc gtatatcgtc
    70921 cctgagacct tgctacagca acattagagt taaccttctc attatctttg acatgttctt
    70981 gtttttgacg attgatttca tctttagttc gaacattatc agcatgagct gcatctttca
    71041 ggtagacata atattttcca tcgaccttga tgatataacc acccttgact tcattgacaa
    71101 tatcagcgtc tttaagttga tagtttggat ccttcatcaa gagttcttca ctaaagaggg
    71161 catcataagg aactttccca ttatagtaat gatagtggtc accgtgtgac gttacatagc
    71221 cctgatctgt aattttgatt acaatttgct cagcctgaat tccttctttc tggctaacct
    71281 ggtctggtgt caagttttca cttttctgac ttgactggct gccatccaca taagagacac
    71341 gattattgtc cttattttcc tgcgaacgat gctggtttag tgcataggca catagactca
    71401 aggatacgat aacagctgat ccagctgcta tatatttttt actaaatttc ataaatccct
    71461 catttcaata aatgatgaag tttttttctc aacttctttt actttattaa atagttttct
    71521 aaaccgatta tttaaccatt taattaacca gtaaatagtc tactatttaa aattactttt
    71581 gtcaagtttc tgttacgttt ttctaaaaaa gagaagtaac acgaaaggtt acttctccat
    71641 aaaatatgct ccattcattt tactactgta taggagccgg ttgactttct tttaacaaag
    71701 ccaagagact atctacttct gctgaaatag tattattatc tttcgttccg agaagaagac
    71761 tactttttag accagtcaat gtctccatag cattttgtct aatactagaa tctgttactt
    71821 tttctagcaa ggcctccgcc tctgctatct tagcgttaat aacagaatgc tctacttgag
    71881 gaatttcagc ctcatctgta gtatcttcag cttcttcctc tgtctcttcc gtatcagtgc
    71941 ttggtttata aagattatct gctgaaggat ttaaaccagc gtgattctct ttttcatcag
    72001 attcagggtg agttggctca cttacttcat catgttcctt atcttcctca ggtttttctg
    72061 tctgaggttt ctccgtttga ttggtatcag cttgaccatt tttgtttctt tgaacatggt
    72121 cgctagcgtt accaaaacca ttatctgaat gcggacgttc gtttggatgt tcgacatagt
    72181 acttgacagt cgccaaaaga tcctcaagag tatacccctt aggtgcctca taaaggcctt
    72241 cgtcaaacca ctcaaatttg atgttatggt aatggtcata atgaggtatg attaaactac
    72301 cgtttttgac ttctacagta tattgaagat tgtaaggcac acgatcaagt ggcaccttct
    72361 tagctgcttt cacgcggttg tagatagctt ctgctccttt tgcctcagta tttcctgaat
    72421 cctgatg
//
LOCUS       DAVBNN010000002        67959 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBNN010000002 DAVBNN010000000
VERSION     DAVBNN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67959
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.002"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ847_000076"
     CDS             <1..116
                     /locus_tag="VQ847_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3049491.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ847_000077"
     CDS             135..1652
                     /locus_tag="VQ847_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3049492.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ847_000078"
     CDS             1777..3105
                     /locus_tag="VQ847_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3049493.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ847_000079"
     CDS             3358..4224
                     /locus_tag="VQ847_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3049494.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ847_000080"
     CDS             4240..5079
                     /locus_tag="VQ847_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3049495.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ847_000081"
     CDS             5351..5803
                     /locus_tag="VQ847_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3049496.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ847_000082"
     CDS             5900..6244
                     /locus_tag="VQ847_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049497.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ847_000083"
     CDS             6528..7172
                     /locus_tag="VQ847_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3049498.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ847_000084"
     CDS             7341..8258
                     /locus_tag="VQ847_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3049499.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ847_000085"
     CDS             8276..9160
                     /locus_tag="VQ847_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3049500.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ847_000086"
     CDS             complement(9176..10027)
                     /locus_tag="VQ847_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3049501.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ847_000087"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ847_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3049502.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ847_000088"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ847_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3049503.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ847_000089"
     CDS             13086..14129
                     /locus_tag="VQ847_000089"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3049504.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ847_000090"
     CDS             14213..15586
                     /locus_tag="VQ847_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3049505.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ847_000091"
     CDS             15573..16184
                     /locus_tag="VQ847_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3049506.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ847_000092"
     CDS             16275..16979
                     /locus_tag="VQ847_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3049507.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ847_000093"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ847_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3049508.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ847_000094"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ847_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3049509.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ847_000095"
     CDS             19852..20523
                     /locus_tag="VQ847_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3049510.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ847_000096"
     CDS             20533..21072
                     /locus_tag="VQ847_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3049511.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ847_000097"
     CDS             21072..21335
                     /locus_tag="VQ847_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3049512.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ847_000098"
     CDS             21332..22117
                     /locus_tag="VQ847_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3049513.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ847_000099"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ847_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3049514.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ847_000100"
     CDS             23262..26054
                     /locus_tag="VQ847_000100"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3049515.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ847_000101"
     CDS             26457..26837
                     /locus_tag="VQ847_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049516.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ847_000102"
     CDS             27031..27321
                     /locus_tag="VQ847_000102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049517.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ847_000103"
     CDS             27372..28064
                     /locus_tag="VQ847_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3049518.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ847_000104"
     CDS             28117..30528
                     /locus_tag="VQ847_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3049519.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ847_000105"
     CDS             30778..31479
                     /locus_tag="VQ847_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049520.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ847_000106"
     CDS             31481..34189
                     /locus_tag="VQ847_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3049521.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ847_000107"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ847_000107"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3049522.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ847_000108"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ847_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3049523.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ847_000109"
     CDS             complement(35860..36708)
                     /locus_tag="VQ847_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3049524.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ847_000110"
     CDS             complement(36705..37427)
                     /locus_tag="VQ847_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3049525.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ847_000111"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ847_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3049526.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ847_000112"
     CDS             complement(39733..40362)
                     /locus_tag="VQ847_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3049527.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ847_000113"
     CDS             41358..43580
                     /locus_tag="VQ847_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3049528.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ847_000114"
     CDS             43610..44053
                     /locus_tag="VQ847_000114"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3049529.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ847_000115"
     CDS             complement(44320..44505)
                     /locus_tag="VQ847_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049530.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ847_000116"
     CDS             complement(44524..44937)
                     /locus_tag="VQ847_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049531.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ847_000117"
     CDS             complement(45068..45715)
                     /locus_tag="VQ847_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3049532.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ847_000118"
     CDS             complement(45741..45932)
                     /locus_tag="VQ847_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049533.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ847_000119"
     CDS             complement(45913..46563)
                     /locus_tag="VQ847_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3049534.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ847_000120"
     CDS             46675..47517
                     /locus_tag="VQ847_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3049535.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ847_000121"
     CDS             47593..48030
                     /locus_tag="VQ847_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3049536.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ847_000122"
     CDS             48098..48400
                     /locus_tag="VQ847_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049537.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ847_000123"
     CDS             complement(48491..49564)
                     /locus_tag="VQ847_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3049538.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ847_000124"
     CDS             49720..50397
                     /locus_tag="VQ847_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3049539.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ847_000125"
     CDS             50390..51364
                     /locus_tag="VQ847_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3049540.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ847_000126"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ847_000126"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3049541.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ847_000127"
     CDS             complement(53414..53737)
                     /locus_tag="VQ847_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3049542.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ847_000128"
     CDS             54596..55225
                     /locus_tag="VQ847_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3049543.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ847_000129"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ847_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3049544.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ847_000130"
     CDS             56451..57065
                     /locus_tag="VQ847_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3049545.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ847_000131"
     CDS             complement(57358..58107)
                     /locus_tag="VQ847_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3049546.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ847_000132"
     CDS             58240..60576
                     /locus_tag="VQ847_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3049547.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ847_000133"
     CDS             61105..62568
                     /locus_tag="VQ847_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3049548.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ847_000134"
     CDS             62561..62989
                     /locus_tag="VQ847_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3049549.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ847_000135"
     CDS             62967..63416
                     /locus_tag="VQ847_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3049550.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ847_000136"
     CDS             63444..63755
                     /locus_tag="VQ847_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3049551.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ847_000137"
     CDS             63781..64866
                     /locus_tag="VQ847_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3049552.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ847_000138"
     CDS             64877..65572
                     /locus_tag="VQ847_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3049553.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ847_000139"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ847_000139"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3049554.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
BASE COUNT        20092 a        12434 c        15258 g        20175 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg taggcttgga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctaatagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcgtg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgctggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggatc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccggt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatt
//
LOCUS       DAVBNN010000003        66209 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBNN010000003 DAVBNN010000000
VERSION     DAVBNN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.003"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            1..393
                     /locus_tag="VQ847_000140"
                     /pseudo
     CDS             1..393
                     /locus_tag="VQ847_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            396..1408
                     /locus_tag="VQ847_000141"
                     /pseudo
     CDS             396..1408
                     /locus_tag="VQ847_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1383..1961
                     /locus_tag="VQ847_000142"
     CDS             1383..1961
                     /locus_tag="VQ847_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3049555.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(2018..2302)
                     /locus_tag="VQ847_000143"
     CDS             complement(2018..2302)
                     /locus_tag="VQ847_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3049556.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2356..3291)
                     /locus_tag="VQ847_000144"
     CDS             complement(2356..3291)
                     /locus_tag="VQ847_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3049557.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3395..3838
                     /locus_tag="VQ847_000145"
     CDS             3395..3838
                     /locus_tag="VQ847_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3049558.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            3954..4220
                     /locus_tag="VQ847_000146"
     CDS             3954..4220
                     /locus_tag="VQ847_000146"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3049559.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            4217..4591
                     /gene="crcB"
                     /locus_tag="VQ847_000147"
     CDS             4217..4591
                     /gene="crcB"
                     /locus_tag="VQ847_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3049560.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            4585..4914
                     /gene="crcB"
                     /locus_tag="VQ847_000148"
     CDS             4585..4914
                     /gene="crcB"
                     /locus_tag="VQ847_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3049561.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            5033..5380
                     /gene="rplS"
                     /locus_tag="VQ847_000149"
     CDS             5033..5380
                     /gene="rplS"
                     /locus_tag="VQ847_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3049562.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5422..5493
                     /locus_tag="VQ847_000150"
     tRNA            5422..5493
                     /locus_tag="VQ847_000150"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5455..5457,aa:Arg,seq:cct)
     gene            complement(5659..6657)
                     /locus_tag="VQ847_000151"
     CDS             complement(5659..6657)
                     /locus_tag="VQ847_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3049563.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(6700..7506)
                     /gene="yidA"
                     /locus_tag="VQ847_000152"
     CDS             complement(6700..7506)
                     /gene="yidA"
                     /locus_tag="VQ847_000152"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3049564.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(7519..8823)
                     /locus_tag="VQ847_000153"
     CDS             complement(7519..8823)
                     /locus_tag="VQ847_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3049565.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            8895..9272
                     /locus_tag="VQ847_000154"
     CDS             8895..9272
                     /locus_tag="VQ847_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3049566.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            9363..9695
                     /locus_tag="VQ847_000155"
     CDS             9363..9695
                     /locus_tag="VQ847_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3049567.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            9707..11278
                     /gene="ffh"
                     /locus_tag="VQ847_000156"
     CDS             9707..11278
                     /gene="ffh"
                     /locus_tag="VQ847_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3049568.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(11473..12756)
                     /locus_tag="VQ847_000157"
     CDS             complement(11473..12756)
                     /locus_tag="VQ847_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3049569.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(13010..13723)
                     /gene="rsmG"
                     /locus_tag="VQ847_000158"
     CDS             complement(13010..13723)
                     /gene="rsmG"
                     /locus_tag="VQ847_000158"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3049570.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            13817..14377
                     /locus_tag="VQ847_000159"
     CDS             13817..14377
                     /locus_tag="VQ847_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3049571.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            14379..15278
                     /gene="htpX"
                     /locus_tag="VQ847_000160"
     CDS             14379..15278
                     /gene="htpX"
                     /locus_tag="VQ847_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3049572.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(15322..16881)
                     /locus_tag="VQ847_000161"
     CDS             complement(15322..16881)
                     /locus_tag="VQ847_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3049573.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            17606..18148
                     /locus_tag="VQ847_000162"
     CDS             17606..18148
                     /locus_tag="VQ847_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3049574.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            18148..18777
                     /gene="nth"
                     /locus_tag="VQ847_000163"
     CDS             18148..18777
                     /gene="nth"
                     /locus_tag="VQ847_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3049575.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            18988..19509
                     /gene="pyrR"
                     /locus_tag="VQ847_000164"
     CDS             18988..19509
                     /gene="pyrR"
                     /locus_tag="VQ847_000164"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3049576.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            19528..20451
                     /locus_tag="VQ847_000165"
     CDS             19528..20451
                     /locus_tag="VQ847_000165"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3049577.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            20501..21580
                     /gene="carA"
                     /locus_tag="VQ847_000166"
     CDS             20501..21580
                     /gene="carA"
                     /locus_tag="VQ847_000166"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3049578.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            21893..25069
                     /gene="carB"
                     /locus_tag="VQ847_000167"
     CDS             21893..25069
                     /gene="carB"
                     /locus_tag="VQ847_000167"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3049579.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(25344..26153)
                     /locus_tag="VQ847_000168"
     CDS             complement(25344..26153)
                     /locus_tag="VQ847_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3049580.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(26155..26958)
                     /locus_tag="VQ847_000169"
     CDS             complement(26155..26958)
                     /locus_tag="VQ847_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3049581.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(26968..28455)
                     /gene="tacF"
                     /locus_tag="VQ847_000170"
     CDS             complement(26968..28455)
                     /gene="tacF"
                     /locus_tag="VQ847_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3049582.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            28791..29498
                     /locus_tag="VQ847_000171"
     CDS             28791..29498
                     /locus_tag="VQ847_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3049583.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            29503..30525
                     /locus_tag="VQ847_000172"
     CDS             29503..30525
                     /locus_tag="VQ847_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3049584.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            30542..31411
                     /gene="licA"
                     /locus_tag="VQ847_000173"
     CDS             30542..31411
                     /gene="licA"
                     /locus_tag="VQ847_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3049585.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            31401..32279
                     /locus_tag="VQ847_000174"
     CDS             31401..32279
                     /locus_tag="VQ847_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3049586.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            32291..32980
                     /locus_tag="VQ847_000175"
     CDS             32291..32980
                     /locus_tag="VQ847_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3049587.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            33076..33924
                     /gene="dprA"
                     /locus_tag="VQ847_000176"
     CDS             33076..33924
                     /gene="dprA"
                     /locus_tag="VQ847_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3049588.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            34808..35851
                     /locus_tag="VQ847_000177"
     CDS             34808..35851
                     /locus_tag="VQ847_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3049589.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            36018..38105
                     /gene="topA"
                     /locus_tag="VQ847_000178"
     CDS             36018..38105
                     /gene="topA"
                     /locus_tag="VQ847_000178"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3049590.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            38326..38685
                     /locus_tag="VQ847_000179"
     CDS             38326..38685
                     /locus_tag="VQ847_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3049591.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            38778..39410
                     /locus_tag="VQ847_000180"
     CDS             38778..39410
                     /locus_tag="VQ847_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3049592.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            39454..40110
                     /locus_tag="VQ847_000181"
     CDS             39454..40110
                     /locus_tag="VQ847_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3049593.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            40129..40761
                     /locus_tag="VQ847_000182"
     CDS             40129..40761
                     /locus_tag="VQ847_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3049594.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            40789..41223
                     /locus_tag="VQ847_000183"
                     /pseudo
     CDS             40789..41223
                     /locus_tag="VQ847_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
     gene            41235..42272
                     /gene="leuB"
                     /locus_tag="VQ847_000184"
     CDS             41235..42272
                     /gene="leuB"
                     /locus_tag="VQ847_000184"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3049595.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VEWIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIYGSA
                     PDIAGQGIANPISMILSVAMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            42269..42538
                     /locus_tag="VQ847_000185"
     CDS             42269..42538
                     /locus_tag="VQ847_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3049596.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            42542..42901
                     /gene="leuD"
                     /locus_tag="VQ847_000186"
     CDS             42542..42901
                     /gene="leuD"
                     /locus_tag="VQ847_000186"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3049597.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            43120..43263
                     /locus_tag="VQ847_000187"
     CDS             43120..43263
                     /locus_tag="VQ847_000187"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049598.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            43363..43536
                     /locus_tag="VQ847_000188"
     CDS             43363..43536
                     /locus_tag="VQ847_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049599.1"
                     /translation="MTDVRGTSCFVIKFGKADEQLAAKLWEEGKMVYASSTSMIKRLK
                     LAMRARCNGVYGR"
     gene            43526..43687
                     /locus_tag="VQ847_000189"
     CDS             43526..43687
                     /locus_tag="VQ847_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049600.1"
                     /translation="MVDKNGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            43850..45781
                     /locus_tag="VQ847_000190"
     CDS             43850..45781
                     /locus_tag="VQ847_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3049601.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEKLLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            45768..47084
                     /locus_tag="VQ847_000191"
     CDS             45768..47084
                     /locus_tag="VQ847_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3049602.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            47259..48245
                     /locus_tag="VQ847_000192"
     CDS             47259..48245
                     /locus_tag="VQ847_000192"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3049603.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            48309..48380
                     /locus_tag="VQ847_000193"
     tRNA            48309..48380
                     /locus_tag="VQ847_000193"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48342..48344,aa:Arg,seq:ccg)
     gene            48563..49261
                     /locus_tag="VQ847_000194"
     CDS             48563..49261
                     /locus_tag="VQ847_000194"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3049604.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            49252..52791
                     /gene="smc"
                     /locus_tag="VQ847_000195"
     CDS             49252..52791
                     /gene="smc"
                     /locus_tag="VQ847_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3049605.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVRNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            52788..53582
                     /locus_tag="VQ847_000196"
     CDS             52788..53582
                     /locus_tag="VQ847_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3049606.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            53582..54400
                     /locus_tag="VQ847_000197"
     CDS             53582..54400
                     /locus_tag="VQ847_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3049607.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            54404..55693
                     /gene="ftsY"
                     /locus_tag="VQ847_000198"
     CDS             54404..55693
                     /gene="ftsY"
                     /locus_tag="VQ847_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3049608.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEMEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPNSQEVTEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(55739..57226)
                     /locus_tag="VQ847_000199"
     CDS             complement(55739..57226)
                     /locus_tag="VQ847_000199"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3049609.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGIKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(57375..58115)
                     /locus_tag="VQ847_000200"
     CDS             complement(57375..58115)
                     /locus_tag="VQ847_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3049610.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(58115..60280)
                     /locus_tag="VQ847_000201"
     CDS             complement(58115..60280)
                     /locus_tag="VQ847_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3049611.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            60453..61406
                     /locus_tag="VQ847_000202"
     CDS             60453..61406
                     /locus_tag="VQ847_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3049612.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            61483..63471
                     /gene="uvrB"
                     /locus_tag="VQ847_000203"
     CDS             61483..63471
                     /gene="uvrB"
                     /locus_tag="VQ847_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3049613.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            63481..64044
                     /locus_tag="VQ847_000204"
     CDS             63481..64044
                     /locus_tag="VQ847_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3049614.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            64010..64498
                     /locus_tag="VQ847_000205"
     CDS             64010..64498
                     /locus_tag="VQ847_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3049615.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            64572..65039
                     /locus_tag="VQ847_000206"
     CDS             64572..65039
                     /locus_tag="VQ847_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3049616.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(65036..65551)
                     /locus_tag="VQ847_000207"
     CDS             complement(65036..65551)
                     /locus_tag="VQ847_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3049617.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(65563..66090)
                     /locus_tag="VQ847_000208"
     CDS             complement(65563..66090)
                     /locus_tag="VQ847_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3049618.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        20124 a        11879 c        14502 g        19704 t
ORIGIN      
        1 cgatttggcg aaatgtaaaa aaatatgagg agttcggact cgactctctc tttcaagaaa
       61 cacgtggtgg tcgtaaccat gcatatatga cggttgagca agagaaagcc tttcttgctc
      121 gccatttgaa ggctgcagag gcaggagaat ttgttacaat tgatgcctta tatcaggctt
      181 ataaaaagga gttaggtcgt tcctacacac gtgatgcctt ctatcaactg ttgaagcacc
      241 atggttggcg aaatattatg ccacgtccag aacatcctag gaaagcagac gctcaaacca
      301 ttgtcgcgtc taaaaataaa atcttaattc aagaagacaa gaaagcgctt taaatatagt
      361 agacgttttc gtaaggttcg cttgatgtac caaatagtac gcccatgcaa aagaatatct
      421 attttgttgt cttggacctg catacgacgg atagagataa aattatccag ctattcaagg
      481 attggacgga ttatagtgcc aagttggtcg agggggaatt ggttaaaaaa gatggacaga
      541 atgctctctt tcctccgagc gatactggtg agacagttgg gctcaatcct catcgtttga
      601 cgctgacttt tggtgtatct gcaagtttct tgaaaaagat gaacttggaa aacaagcgcc
      661 ctcgactgtt cagggattta cctctatttc ctaaggagca attacgtgaa aaatatactg
      721 gtggagatat tgtgattcat gcttgtgcag atgatgagca aattgccttt cacgctattc
      781 gcaatctcat acataagggg agaaatgcgg tgccccttcg ttggagtcag tctggatttg
      841 cagctatcgg ggaccgaatg gagactccgc ggaacctctt tggttttaag gatggaacag
      901 caaatccaac caaggagcaa gactttgacc gcgttatctg ggctgatagt aaggactgga
      961 tggaaaatgg ttcttatatg gcagttcgtc ggattcagat gtttttagag acctgggacc
     1021 gcactggtct ctaagaacaa gaaaatacct ttggtcgtta caaggaaagt agtgcccctt
     1081 tcggtaaaaa aatgagtttg atgaagtgaa tttgagtttt ttgctagatg attcgcatgt
     1141 tcgtttggct aagtaagtgg acaagccact tttgcgttgt tcttactctt actcagatgg
     1201 cattgatgaa aagactggtc agtttgatac gggtttgctc ttcatttctt tccagaagga
     1261 tcctgataac tttgttaagg ttcaaactaa tctaggtgct actgataaga tgaatgaata
     1321 catcactcac ataggtagtg gactttttac ttgctttggt ggtgtggaga aaggagacta
     1381 cattggtcag aaattattgg aaagctagga gctggttgct tgttttagct ttgtcatttt
     1441 taattctttc cccagtaggt gcccaagaaa gtttgagttc ttatttcgta aaaatcacag
     1501 atacttctaa agcggtcaaa aatggcaatc agtctgaggc ccagaaactt gttcaagaga
     1561 tggcatcaga cttcgaaaga gtagaaaata aggattctga ggttggtaag attgttaagg
     1621 aaaagttagc tctatctgga gatattactg aagccaaact caccgaaatt tcctcagctc
     1681 tattagcttt tgaaaaagaa caaaatcctg ttgacctaga tgcggaaaag gaaaaattgg
     1741 taaaccgtct aagtcctcgt tttgaaacct tagagcaggc cattgcctcc aaagatttgg
     1801 aaaaagtccg agaagctttt aagaaaatga attccacttg gaccatcaat gaaagtgtgg
     1861 ttcgtgacaa tagtatagct cattatggac gtgttgaaac agctatttcc ttcctgccta
     1921 gtagcatgga aaccgaacct acagatgagt ctggaacatg aaaacagcag ttgatttcaa
     1981 gaaacaaaaa ggaacagccg aaactgttct cttatcatta tttgagaccg tattttttgt
     2041 tgaaacgatc cacgcgtcca tctgcttgag tgaacttttg acgtccagtg tagaatgggt
     2101 gtgagtctga tgaaatttcc acacggatca atgggtaagt ctcgccttcg aactcaactg
     2161 tttcgttaga gcgttttgtt gaaccgctaa ggaattggta accagtagtt gtgtccatga
     2221 agacaactgg gcgatattct ggatggatat cttttttcat tttgcaatat ttcctttctg
     2281 ccatggtctc tttgcgagcc atagattgtt accatactag tctatcagat tctgaaaagt
     2341 ttggcaagta ttttatcagt ttttaagcaa gttttttaac ttttggtaga tgatttcgtt
     2401 ttcctctagg ctataggaat tagcaccact tgctagaggg tggcctccac catcatgttc
     2461 cttggcaatt tcattgatag gatggatttt actgcgtaag cgaacgcggt agtggccatc
     2521 agcctgttcc acaaaaattc cccagagact aacactatca atacgcccag gtgcacttac
     2581 aatggctgca gtttcagcat cggttacatt gtattgtttc aagacttctt gactcaggat
     2641 aacgcgagca gcaccatttt catccacttc cagatggtcg tagatgtagc cttgcagttt
     2701 agcaattttg tagctcatag tgtccatttt gcgagtgaga gccgcaaagt caaagttatg
     2761 ttctctcaaa taagcagcca ggcgaagagt ccgtgcagtg gtagaagggt agaggaagcg
     2821 acctgtatca ccgacaattc ctgcaaagag caactcagca tcgcgatctg ccaaggctag
     2881 ttgggttgtt tgggcaaata gggtaatcat ctcgctagcg ctacttgaac tagtatcgac
     2941 ccaagacagg tcaccgtata catcatcatt tggatggtgg tcaatcttaa tgagaaaatc
     3001 accttgacta tagcgtttat catcgatacg agcagtatta gctgtatcac agacgatgac
     3061 aagtgcgcct tggtaggccc tatcttcaac aagatccatc tcagccatcc aagtaagagt
     3121 tggttcatca aaaccgacgg ctttgatggt tttttctggg aaatgatgtt ccagcaaggc
     3181 tttcaatccc acctgacttc ccaaggcatc agggtctggt ttcatatgac gatgaatgat
     3241 aatggtgtcg tattctttaa ttttttctaa aatttgttgg caaatctcca taaataacct
     3301 caattctttc tcatttcatt gtagcacaag aatttttatt tttaaaatga aaaagatgtg
     3361 atataatgga gaaagataaa ttgaggagga cgatatggca ttagcaaaaa ttgtatttgc
     3421 cagtatgacc ggtaataccg aagaaattgc agatattgta gcagacaaat tacgtgactt
     3481 gggcttggat gttgatgttg atgaatgtac aactgttgac gcttcagact tcttggaagc
     3541 agacatcgct atcgttgcga cctatactta tggtgatggt gaattgccag atgagatgat
     3601 ggacttctac gaagacctag cagatctcaa cttgaatggc aaaatctacg gagtggtcgg
     3661 ctcaggagat accttctacg atgaattctg taaggctgtt gatgactttg accgtgtctt
     3721 tgtgtcaaca ggagcagaaa aaggttcaga gtgtgttaaa gttgatcttt ctgccgagga
     3781 agaagatatt gaacgcttgg aacaattcgc agaagaattg gttgctaaag taggataagc
     3841 ataaaagtgc gctgatgtaa tcaatcagtg catttttctt atcgagagtt gggattttac
     3901 tagcctaatt gatggctttt tgatacaata attcaaataa aggaggagac tgtatggatt
     3961 tagatattat tcgtcaagaa atcgatcaaa tcgacgacca aattgtcaaa ctgttagaag
     4021 aacgaatgca tttagttgag ggggtggttg cttataagaa agcttcaggt aaaccgattt
     4081 tagatactaa gagagaagaa gttatttttg aaaaggttgg gagtcgtgta gaggacaagc
     4141 gctatcagga gactattgta gcgacttttt cggacatact caaacgttcg cgtgattatc
     4201 aggatcaaaa tatcaaatga aaaaagaaca attttatccg ctaggaattt ttctagctgc
     4261 tatgttgggc ggacttgtcc gatatctagt ttccacctgg ttaccagcca gtccagactt
     4321 tccttggggc actctctttg tcaactatct gggaattttc tgcttgattt atcttgtcaa
     4381 gggctatctg gtctataagg ggactagtaa gggcttgatt ttagcactgg ggacgggttt
     4441 ttgcggaggt ttaacaactt tttccagcct aatgcttgat actgtgaagc tgcttgatac
     4501 agggcgttat cttagtttga tactgtattt gcttttgagt atcggtggag gcctgctttt
     4561 agcttactat ttggggagga agaaatggta atcgtctatc ttgcaatcgc ctgtggcttg
     4621 ggagcactcg tacggtattt cttttctcgc tataatcaag tttctaaatt gccactcgga
     4681 acgctcatag ctaatctttt aggttgtttt ttaattggag tattctacaa tcatgtagag
     4741 tctaaggaag tatatgctat tctagcaaca ggattttgtg gcggtttaac aactttttcg
     4801 accttgaatg acgaacttca aagactgcta agtgataaga aggtctttta ttcttacctg
     4861 actttgactt acataggtgg tttggttgcg atttttttag gaattttgct ataaatttct
     4921 ttactttttt ttagaaattt ggtaaactgt atcttgtgtg taatggacgc acaaaaatac
     4981 agtttatccg ctgaggaaga ttcctcaaga ttgacaaaga taggagaata aaatgaatcc
     5041 attaatccaa agcttgactg aaggtcaact tcgtacagat atcccatcat tccgtcctgg
     5101 tgatactgtt cgtgtacacg cgaaagttgt cgaaggtaac cgcgaacgta tccagatttt
     5161 tgaaggtgtt gttatcgcac gtaaaggtgc tggaatctca gaaaactaca cagttcgtaa
     5221 aatctctaac ggtgtaggtg ttgagcgtat cttcccaatc cacactccac gtgttgaaaa
     5281 aatcgaagtt gttcgttacg gtaaagtacg tcgtgcgaaa ttgtactact tgcgtgctct
     5341 tcaaggtaaa gcagctcgta tcaaagaaat ccgtcgttaa ttcgactaaa aaactctgct
     5401 tttcagcaga gtttttatct agctccctta gttcaatgga tataacaact ccctcctaag
     5461 gagtagttgc aggttcgatt cctgcagggg gcagtaatta gatatcaaag aagtttgtca
     5521 aaaagtcttt gatattaaaa gaacgcataa tataggggat tgtctccata atattatgcg
     5581 ttttattatt gaaaaatttg ggcaatcatc agataaaatt gagactatat cgagtatata
     5641 aatgtttgta tagtcaattt attcaaaatc gtcaagttct aaattattta aaggactata
     5701 acattcatat ttctttaagt aattgtttat ttcttcagca gtggaacgag gtaaattaac
     5761 tcttaaatag tcaatatctt ccttagataa aaaatgattt gcattcaaaa ttgagaagcg
     5821 aaataatgct tcatcaaaag caaaatcata atcgtcatca gataatgatt ccattaatgt
     5881 ttgaatatgt tttagtgagt agtcaggtat cgaatcggga taatatactg gataatcagt
     5941 ggctgaaaaa ttgttttcta atcctgaaat agtaattatc aaagattcta tgtaatatat
     6001 taaagcatgt ttaatattac cttcttgttc caaatgtctt ccctgagcct ttcgtgtgtt
     6061 agataagcat ccaaaatctc ctgatacagt attcctatga gcttgtttat ttaagagact
     6121 ccattttata tcaccaaaag ttgctttaaa agagatattg tttttttctt tacaataatc
     6181 ttccatactt atgtctttat catagtatgc tttgatatag tcactatgtt cgataataag
     6241 attttgtgct tcttttgtta gtttaaattc gaacggaata tctaatttgt caacgttgat
     6301 attattaatt attcttgtaa ttaattctgc tttttttcca gaagtagcta aattatgttt
     6361 agataatata gtttttaatt ctactacttt aagatatgat aaagtcttat ttttagtgaa
     6421 gtatcctaat ttgtataatt gattgtgtgt agattcaggg tcaatttgaa gagagtattt
     6481 aaaatatctt gggaaattat aatttctccc tgttttttga gtccaatcta tgagtatgag
     6541 ttgcccagga gtaaggccgc actctaattt gtttaggtaa aaattgttac aatcagaatt
     6601 tgtgtctcta ttatgattat tttgttttaa attaaatagt ttgctaaaaa aattcattgg
     6661 attttattgc taatcaattc ttattgaaaa atgatacttt tacagtaccc atgtacggat
     6721 ggcatgggca acgccagatt catcattaga tttagtgatg tatttggcga tttttttgat
     6781 ttctggattt ccattttcca tgacaacagg gttgccaacg acttccagca tggcacggtc
     6841 attttcttcg tctccgatag ccatggtttc atctttggtt aatcctagtt tttcagctaa
     6901 gtgagtaata gctgaaccct tgtctacatt ctttttaagg agttcgaggt agaaaggagc
     6961 agatttgttg atagagtagt gctcgtaaaa ttcggctggt attttttcaa tcgcagcatc
     7021 gagaatttct ggttcatcga taaacataca tttaacaatt tctttgccag ccatttcttc
     7081 aggggtacgg tagaagatag gcatgctgac gagggttgat tcgtgtacag tgtatgttcc
     7141 gatattgcga tttgcagtat agataccgtc cttggtaatg gcatgcatgt ggacaccgag
     7201 cttgcgactg aggaattcca tatccagata atcctcatag gtcaaggatt cgctgataat
     7261 ctcatggcca gtagcagttt cttggacaag ggcaccattg aaggtcacca catagtcacc
     7321 ttggtctctc aactgcaagt cgtctagaag tttggcaaca cctgcgatgg ggcggccagt
     7381 tgcaatcacg actttgacac cagcttcttt ggcatcttgg atggcagaaa agacttcagg
     7441 agtgatttcc ttttggctgt tgacaagggt tccgtcgata tcaacggcaa ttagtttaat
     7501 actcataaat ttcctcttct agtttttatt tggggtaaaa tgatcgttct caatcaagta
     7561 taaaaattgc tgggtaatgc tagcaaagat actgttttga tctaacattt ctttcggaaa
     7621 atagaaacga ttatctccgt gacgactacc agcaagggat tggacgatag gagacaggct
     7681 agagagttcg gccagttctc cattcttttg taaaatctca atctgtgtcc gtggattttc
     7741 agattcggga cgatagatat cataagggag gtcaaagttc ttatgaatgg cagtatagta
     7801 gtcgggatca aagccaatgt cctcaaccaa ttttctcatg ctagcgagtt ggtcttgatc
     7861 ttcttgtgaa aaggtaatgg atttaaagac cttgcggttg acaaagcgtt gcgataaatc
     7921 tgcgagaatt ttgtcaggac tggtcatcca gagctggaag taggtattca tcacaccatc
     7981 atctagagcc agatagtcag acaaggtcac atttttttca aagaaaggca ggaggtgtgg
     8041 ggaagttcgt gcaaagaagt ctttgtcctt agggtagagt tccttagcgc gcttgagaag
     8101 attctgtagg agaacttcca tagcgcgtgt tgctgggtgg aaatagacct gcatatacat
     8161 ctggtagcga ctgaggacat agtcttcgat ggcgtgcatg ccattgcgct gaaaggcgat
     8221 accattttcg ataggacgaa tgactcggag gattcgagtc aggtcaaatt ccccatagga
     8281 tgctcctgta aaataggagt cacgcaagag atagtccatg cgatctgcgt caatctgact
     8341 agaaatgagt tgtacgacct gcttgttagg ataggtatgg tctatgacac tggcaacttt
     8401 ctctggaaaa tcgggcgcta cttgtagcaa gacttggtga atctctgtct caggactttg
     8461 aataatctcc tgagtaatag cttcatggtc tgtatcaaag agatgttcaa aagtatggga
     8521 gtaggcgcca tgcccaaggt catgtaggag agcagcgatc atggtcaaga gagactcggc
     8581 aggattccat tcctcaggat atttttcttc gaaaatctct gtgatgcgtc gtgcaatttc
     8641 atagactcct agacagtgag agaagcgact gtgttctcca ccgtggaagg tataactgga
     8701 agttcccagt tgtttgatcc ggcgcaaacg ctgaaattct tttgtattaa tcaagtcata
     8761 gatgatttga ttaatgacat ggatgtagtt gtgaactggg tcacggaata ctttttcgtt
     8821 catatgacca ttatagcaaa atcctgctct ttttggtaaa atagtaggac aagagacaag
     8881 aaagagggcc tgatgtgaag attcggatgc gaaatacaat tcagtttgat gagcagttgg
     8941 aagtgattga ccagctttat gatgtggaag tgcatgaaaa aggagattat agctacctgc
     9001 ttttctataa tgaggaaaag gaaaaagtag tgattaaatt tcatggtcaa gaacttgtga
     9061 tgagccgatt ttctaatccc aagaccatta tgcgctttct aaagaatagc gatagtttag
     9121 cctatattcc tacacctatg ggcatgcagg agtttatcat ccaaacgagc cattatcaag
     9181 ttgataggca aaagattgaa ctagattatc aactacaaaa tcaagaggga catccttttg
     9241 ccagctatca attggaaatt acttggggct aggctcatgt ctttttcaaa tttagctatc
     9301 tatcttcttg gatcggtttc ctagtgtggt agattaggct aatttttggt ataataaaag
     9361 ttatggaaat cgaaaaaacc aatcgtatga atgcgctctt tgaattttat gcggcgcttt
     9421 tgacagataa gcaaatgaat tatatcgagc tctactacgc tgatgattac agccttgctg
     9481 aaattgccga ggagttcggt gtcagtcgtc aggctgtcta tgacaatatc aagcgaacag
     9541 aaaagattct ggaagattat gagatgaaat tgcacatgta ctcggactat attgtccgca
     9601 gtcagatttt tgatcagatt ttggagcgct atcccaagga taactttctg caggagcaga
     9661 tagaaatttt aacaagcatt gataatagag aataagagga agaaaaatgg catttgaaag
     9721 tttaacagaa cgtttgcaga acgtctttaa aaatctacgt aaaaaaggaa aaatctctga
     9781 atctgatgtc caagaggcaa ccaaagaaat tcgcttggcc ttgctcgagg ccgacgttgc
     9841 cttgcctgtt gtaaaggact ttatcaagaa agttcgtgag cgtgcagtcg ggcatgaggt
     9901 cattgataca cttaatcctg cgcaacagat tattaaaatc gttgatgagg aactgacagc
     9961 cgttttaggt tctgatacgg cagaaattat caagtcacct aagattccaa ccatcatcat
    10021 gatggttggt ttacaagggg ctggtaaaac aacctttgct ggtaaattgg ccaacaaact
    10081 caagaaagaa gaaaatgctc gtcctttgat gattgcggcg gatatttatc gtccagctgc
    10141 cattgaccag cttaagacct tgggacaaca gattgatgtg cctgtctttg cacttggaac
    10201 agaagtacca gctgttgaga ttgtacgtca aggtttggag caagcccaaa ctaatcataa
    10261 cgactatgtc ttgattgata ctgcgggtcg tttgcagatt gatgagctcc tcatgaatga
    10321 gcttcgtgat gtgaaagcat tggctcaacc aaatgaaatc ttgcttgtcg ttgatgctat
    10381 gattggtcag gaagcagcca atgttgcgcg tgagtttaat gctcagttgg aagtgactgg
    10441 ggtcatcctt accaagattg atggcgatac tcgtggtggt gctgctctgt ctgttcgtca
    10501 cattactgga aaaccaatca agttcactgg tacaggtgaa aagattacgg acattgaaac
    10561 cttccaccca gaccgcatgt ctagccgtat ccttggtatg ggggatatgc tcactttgat
    10621 tgagaaagct tctcaggaat acgatgaaca aaaagccctt gaaatggctg agaagatgcg
    10681 cgaaaacacc tttgatttta atgatttcat cgatcaatta gatcaggtgc aaaatatggg
    10741 gccgatggaa gacttgctca agatgattcc aggtatggcc aacaatccag cccttcaaaa
    10801 catgaaggtg gatgaacgcc agattgctcg taaacgtgcc attgtgtctt cgatgacacc
    10861 tgaagagcgt gaaaacccaa atttgttaaa tccaagccgt cgccgtcgta ttgctgctgg
    10921 ttctggaaat acattcgtcg aagtcaataa attcatcaag gactttaacc aggctaaaca
    10981 gctcatgcag ggtgttatgt ctggggatat gaataaaatg atgaagcaaa tggggattaa
    11041 tccaaataac cttcctaaaa atatgccaaa tatgggagga atggatatgt ctgcccttga
    11101 aggaatgatg ggacaaggcg gtatgcctga cttatcagct ctcggaggag caggaatgcc
    11161 agatatgagc cagatgtttg gtggcggttt gaaaggtaaa attggtgaat ttgccatgaa
    11221 acagtccatg aaacgtatgg ctaacaaaat gaagaaagcg aagaagaaac gcaagtaaga
    11281 caagagattg atgcaaatct catttgatga gaaaataaag taaaaatttc tatgataaaa
    11341 cgtatagtat caaggtttta gaatatctga tattatacgt tttttgattt taataatttt
    11401 gttaagacac ttttattatg gtatgcgaaa aatccactca gctgtctgag tggattaggt
    11461 gtatttagac tcttagtctt tattttcgta tggcaagatc aagttcaaga tgattcctgt
    11521 catggctgaa agggcagtac ctgaaagtgt aactggacca agtttaagga tagctcctcc
    11581 aagtccaaga accaacatag cacttgcgat gatgaggttt cgcatttgag cgaaatcaac
    11641 acgttcttta atcaagactt tcaaaccatt gctggcgata accccataga gaaggattga
    11701 cataccacca agtacagcgt ttggaatagt tgaaatcaag gcagtgaatt taccaaggaa
    11761 gctgagggca atcgcgatga aggcagcgtt acggataact gagacagaag cgatacgagt
    11821 cataccgata acccctgtat tttctccgta agttgtattg gctggtccac caaggaaggc
    11881 agaaacagaa gttgcgatac cgtcaccaag aagagtacgg tgaagacctg gttcttttaa
    11941 gaattgacga ccacagattt gacccaaaac agtatggtct ccgatatgtt cagaaattgt
    12001 tacgatagcg attggcaaga tagcgatggc ttctggacca aagtaaagat tgtactcttt
    12061 aaaggcacca cctgtgctaa atggcaagta gaaaccagga atttcgaacc agttggcttt
    12121 aagaactggt gtaaagtcaa ccaagccaag agttagtgcg aaaaggtaac caccgataat
    12181 ggcaaagagg aatggaatga ttcgtaggaa gccttttcct tttgtattga taaaggcagc
    12241 aattaggaaa gtaacaacgg ctaccagagc atttttccaa tttccgtctg ctacaagacc
    12301 tgcattggta acagctgaac ctgcaagtcc aagaccgata acgatgatca taggaccgat
    12361 aatgattggt ggcaagagtt tatcaatcca ttttgttcct acaaatcgga tgctggtagc
    12421 aacaaggaca tagaccaaac cagtcaagat aacccctgtt tgggcagcag atacatcccc
    12481 ccccatttct ttcatagcca gtgacatagc tgtgataaag gcaaatgaag aacctagata
    12541 aactggaact ttaaaaccag tagcaatcat gtagatgagt gttccaacac ctgaagcaaa
    12601 aagggcaaca gatacaggca ttcccaaaat caatggtacc aagatggtcg caccaaacat
    12661 ggcgaaaacg tgttggaagc taaggagaat tccttttcca tccgaaggac gttggtcaac
    12721 gtctagtaac aaatcaacag ttgattcttg tttcatataa acctcacttt tgggcatcag
    12781 aaaagagccc attattttac agcaataggc cctcagagta agacttctct aaaatctaga
    12841 ctttaaagag tttcaaatat ttttgcgtct tcgtcacctc acgggatgac attaaaaacc
    12901 tttgcttagg atagtatagc agaaaaaaat gattttgtaa atcatttttt cccgagccta
    12961 gaaataaaag agcgaggctg attttgtaaa catttgttta ctaaaaaatt taaagtgggc
    13021 gtttatttgg cataccagcc ttacgtggat atttatttgg tgtttctttt ttcttttcta
    13081 ccactgtgat atagcgcgga tctctattcg gtagggcgta gctgagattg tcttcgacct
    13141 tactaaaaag gagattgagg gcattcttag cttctaataa ttcctcaggc gcattgctgg
    13201 ccttgagtgc caatagtttg ccaccaacct taaggtaggg aatagtcaat tcagatagga
    13261 cctgcatacg ggcaaccgca cgagctgtta caaaatcata ttgagcacgg aagttcttgt
    13321 cttgggcaaa atcttcggca cgtccgtggt agaaatgaac tccgttcaaa tccagttctt
    13381 gagccaagag ttgtaggaag ttgatgcgct tattgagtga atcaataatg gtcacatcta
    13441 actccggata gagaattttc attggtagac taggaaatcc tgccccagcc ccgatatcaa
    13501 gaagtttgat agtttcattg ggaatcaaac cttgaagaat gggtgcaatc gaatcgtaaa
    13561 aatgtttgag ataaacttct tccttgtccg taatcgccgt caaattaatc ttctcattcc
    13621 actcgaccaa gagctcaaaa taacgttcaa attgttcttt ttgctggttc gaaagtggaa
    13681 gattctgctc ggcaagcaag ttgtaaaatg tttctggttt catagttatt tccttcttta
    13741 gtatcatctt attttaccac aatcatagaa aatttgatat actggtacta atctaaaagc
    13801 agaaaggact tatattatga cttggattat tcttggagtt atcgctctta ttgttatttt
    13861 tgtgattgtt agctataacg gtttggttaa aaatcgtatg caaaccaagg aggcttggag
    13921 tcagattgat gttcagttga aacgtcgaaa tgacctcttg ccgaacttga ttgagactgt
    13981 aaaaggttat gccaaatatg aaggttctac ccttgaaaag gtggcagaac tacgtaacca
    14041 agtggcggca gcgacttcac cagcagaagc tatgaaagcc agtgatgccc tcactcgtca
    14101 ggtttcaggt atttttgcag ttgcagaaag ctatccagat ttgaaagcta gtgctaactt
    14161 tgttaaattg caagaggagt tgacaaacac agaaaataaa atttcttact ctcgtcaact
    14221 ctataacagt gttgtcagca actacaatgt aaaattagaa actttcccga gcaatattat
    14281 cgctggaatg tttggattta aagcggcaga tttccttcaa acacctgaag aggaaaagtc
    14341 ggttcctaaa gttgatttta gcggtttagg tgactaagat gttgtttgat caaattgcaa
    14401 gcaataaacg aaaaacctgg attttgttgc tggtattttt cctactctta gctcttgttg
    14461 gttatgcggt tggttatctc tttataagat ctggacttgg tggtttggtt atcgcactga
    14521 ttatcggctt tatctacgct ttgtctatga tttttcaatc gacagagatt gtcatgtcca
    14581 tgaatggagc gcgtgaggtg gatgagcaaa cggcaccaga cctctaccat gtagtggaag
    14641 atatggctct ggtcgctcag attcctatgc cccgtgtttt catcattgat gatccagcct
    14701 taaatgcctt tgcgacaggt tctaatcctc aaaatgcggc tgttgctgcg acttcaggtc
    14761 tactagctat catgaatcgt gaagaactag aagctgttat gggacatgaa gtcagtcata
    14821 ttcgtaatta tgatatccgt atttcgacta ttgcagttgc ccttgctagt gctatcacca
    14881 tgctttctgg tatggcaggt cgtatgatgt ggtggggtgg agcaggtcgc agacgaagtg
    14941 atgatgaccg agatggaaat ggtcttgaaa tcattatgct agtggtttcc ctactagcta
    15001 ttgtactggc acctctcgct gcaaccttgg ttcagctcgc tatttctcgt cagagggaat
    15061 ttctggcaga tgcatctagt gttgagctga ctcgcaatcc ccagggaatg attaatgccc
    15121 tagataagtt ggacaatagc aaaccgatga gtcgccacgt cgatgatgct agcagtgctc
    15181 tttatatcaa tgatcccaag aaaggtgggg ggttccaaaa actcttttat acccacccac
    15241 ctatctcaga acggattgaa cgtttaaaac agatgtaaaa gaatccagag gtcgtctctg
    15301 gatttttgct atgttgcaaa tttataaatc ttctaaatta actaactcca aaccgtgttc
    15361 tgtcatgcga tagatgatcg agcagacttc ttttaagaaa cgacggtcat gcgaaacagt
    15421 gatgagaccg cctggatagg ttgcaaagag ttttctgatt tggggttgag aagtgggaga
    15481 aaagtttcgt gtgggttcat ccagcaggag aaagtttggt ttgcgcagga ctagatccaa
    15541 aagcaggagt tttccctgtt gtccgccaga taaggagcga atttgatgct gcatttctgg
    15601 ataactgaaa ttgagactgg ctaggtgaga gtggattttc tgaagttcct ctttttcccc
    15661 agttttgctg atataagcta ttggtgataa atccaattgt agttttttgt ggtaatcttg
    15721 tggcataaaa ccaagggaaa tctctctttt atcattcaga agttgcttta atttggctaa
    15781 cagagttgat ttcccaacac catttggccc gataataccg attttttctt gcccacggac
    15841 agttagttgt agtttttgaa ccaaaactcg gtcgtcaatg gacaaatttt ctttttccag
    15901 ttggactaag actttagaag ctggtaatgg ttggatgtct gaaaagaaaa gttggatttg
    15961 ttcctcttca agtggttttt gagtcatgga ctgagctgcc ttttcgtagc gtttttcttg
    16021 tgagaggaca gttttcatct ttttagccaa taggcgaccg gcagtactat ctttggtagc
    16081 tcgaagcgca gtttctacat tttgcttaac tctccgatgt ttttccatgg ttttatcgta
    16141 ggctctttgg ttgttagcag cttgctgact ttgtttggca aaattagcct ttctctgctc
    16201 actatagcta tcatagtcta aatgctctac tagcgtttcc gcttctttac ggtgtttgac
    16261 cagtcgcaag tgaacaatag tgtctgccgt ttcagaaaga aagtcttcat catgggaaat
    16321 gaaaataacg gtttgcctgg tcttttgaat ctggcctttt agccaatcaa ctgtctcaag
    16381 gtctaggtca tttgaaggtt catctaaaaa tagaatctca aagggtttgg ctaactcatg
    16441 gataagctga attttcaaag cttctccccc tgatagattg ccaatctctt ggtcacttgc
    16501 gaaacgattg ctatcaaaat gcaattcctc cgccaaacga tagaggatac tgtagtctaa
    16561 atcaatagaa tctaaaaaga agtagtcgtg taaagttttc tttttcagct cctcgggaag
    16621 tttttgagga atgtaggcca gtgactgata gtcagattgg atgtttccct tgatagtgaa
    16681 atcagacaaa gcttccccca ttaaagtttt aagtaaggtt gatttaccat ttccttcttc
    16741 gccaataata gctacctttt ccccgtcttg tatggtcatg cttaggtcag agacaaggtc
    16801 tcgtaaatct ttgttttgtg tgatggtcag gtgattgatt tttatcatac tattgccctt
    16861 tctagaatgt tcatagtgca taacaaaaag ctctacttta cctagtagag cccaaagtct
    16921 atgtcaaaaa aactctatta acatgccaga aaaagggcat aaaagagcac acaaaaagag
    16981 acaaaaacaa gatctactaa ataaaggttc tttatttgat agacttagtt gttcatgtct
    17041 cccttacctc ctagtattag tatctttata ctatactttt aaggaaattt tgtcaacaga
    17101 aaactggaaa ttctatgctc taaaatccaa aaacaggtct atagagactt agtacgtgtt
    17161 tgacatgctc gtaatggatt ttatcatagt ttcgccaagc agtgcgttct tgattgttta
    17221 gttttaggct acccagtcca atcataggac tggtgggttg gtaaaatttc tcaagatcaa
    17281 ttaagatact gttgttcaac ttttccgttt tttgagttct tgcatagtag tgtttagcag
    17341 ctcttgtagt cgaatatcat ctgccgtacc ctgtttacag ttttggtagc ttttatttaa
    17401 cttggatagg agttgaatga gtttcttgtc ttccgtgtga gcatcctcct tgatctgatg
    17461 tactctttcc ctatagtata gcactaaaaa ataaaactgt catagtgaat atgttaaaat
    17521 ttcgaatttt aattacaaag tttggtgtgc tgatttgtag ccttttcatg gtataatcaa
    17581 gagagtaaat ctttatggag gaagtatgaa attaaatatt caagaaattc gtaagcagtc
    17641 tgaaggtttg aactttgaac aaacgttaga tttagttgat gacctgcgtg cacgtaatca
    17701 agaaatttta gatgtaaaag atatccttgc agttgggaaa gtacaatatg aagaccgtat
    17761 gtatttctta gattatcaac tatcttatac cattgttctt gcttcgagtc gcagtatgga
    17821 gccagttgag ttagttgaat cttatccagt cacggaagtt ttcatggaag gcgcaactaa
    17881 ccagctagat caagaagttt tagatgatga cttggtcttg cccatcgaaa atggggagct
    17941 tgaccttgct gagagtgtat cagacaatat cctgctaaac attcctatca aggtcttgac
    18001 ggctgaagaa gaagctggtc aaggatttgt ctcaggaaat gactggcaaa tcatgacaga
    18061 ggaagaatac caagctcaac aagcagtaaa gaaagaagaa aacagtcctt ttgctggctt
    18121 acaaggacta tttgacggag atgaataatg gtcttgtcaa aaaaacgagc acgaaaggtg
    18181 ctagaagaaa tcattgccct cttcccagat gccaagccta gtcttgattt taccaatcat
    18241 tttgaactcc tggttgcggt catgttatca gcccagacga cagatgcagc ggtaaataag
    18301 gccacaccag gtctctttgt tgcctttcca acaccccaag ctatgtctgt agcgacagag
    18361 agtgagattg cttcacatat ttctcgcttg ggattgtatc ggaataaagc taaattcctt
    18421 aaaaaatgtg cccaacagtt actagacgat tttgatggtc aagtccctca gacacgtgaa
    18481 gaattggaga gtttggcagg tgttggtcgc aagacagcca atgttgtcat gagtgtagga
    18541 tttgggattc cagcctttgc agtggatact catgtggagc gtatttgcaa acaccacgat
    18601 attgtcaaaa aatcagcgac gccacttgag gtggaaaagc gggtcatgga tatcttgccg
    18661 cctgagcagt ggttagctgc ccatcaggcc atgatttatt ttggaagagc catttgccat
    18721 ccaaaaaatc cagagtgtga ccagtaccca caattatatg attttagcaa tttgtaagat
    18781 gctacattga aactttttgc ttgattttaa gcatgctttg tgctatagta aatgataact
    18841 aaatattcct ttaaacctgt cccgtgaggc aggcaaggag cgcgataaag tagaagggtg
    18901 aagtctatac tgtgtgcagt agggctcgct tggctataaa tttcaagtct ccttgtttaa
    18961 ggagactttt ctttttggag gtttgtcatg aaaacaaaag aagttgtaga cgaattgacc
    19021 gtcaaacgag cgattacgcg tattacttat gagattatcg aacgcaacaa agatttgaat
    19081 aagattgtct tggctggtat taaaactcgt ggtgtcttta ttgcccaccg aatccaagaa
    19141 cgtttgaagc agttagaaaa tctttcagtt cctgttgtgg aattggatac taaacctttc
    19201 cgtgatgatg ttaaaagtgg agaagatact tctttggttt ctgtcgatgt gacagaccgc
    19261 gaagttatct tggtggatga tgtgctctat acaggtcgta ccatccgtgc tgctattgat
    19321 aatattgtcg gtcatggtcg tcctgcgcgt gtgagtttag cagttctagt cgatcgtgga
    19381 catagagaat tgccaatccg tccagattac gttggaaaaa atatcccaac cagtcgttct
    19441 gaagaaatca tcgtagagat gacagaactt gatgaccaag acagagttct gattactgaa
    19501 gaagcttaga aagttaaagg agtagccatg tcagaaaatc aacaagcatt gaaccatgtg
    19561 gtgtccatgg aagacctcac tgtcgatcaa gtaatgaaat tgatcaagcg aggaattgag
    19621 tttaaaaatg gagcccagct tccctatgaa gaccatccga ttgtttccaa tctcttcttt
    19681 gaggattcta cacggacaca taagtccttt gaagtcgcag agattaaact tggattggaa
    19741 cgacttgact ttgatgtgaa gactagttcg gttaataagg gtgagacact ttatgacacc
    19801 attttgactc tgtctgcttt aggagtggat gtctgtgtga ttcgccatcc agaggtcgac
    19861 tactatagag aattgattgc tagtccaacg attacgactt ccatcatcaa tggtggagat
    19921 ggttcgggcc aacaccctag ccagagcttg cttgatttga tgaccattta tgaggaattt
    19981 ggccactttg agggtcttaa agttgctatt gcaggtgact tggaccactc acgcgttgcc
    20041 aaatccaata tgcagatttt gaaacgcttg ggatctgaac tctttttcgc tggacctgag
    20101 gaatggagaa gtcaagagtt tgcagactat ggacagtttg taaccattga tgaaatcatt
    20161 gatcaggttg atgtcatgat gtttctccgt gtgcaacacg aacgccatga tagtggagct
    20221 gtattttcaa aagaagacta ccatgcccaa catggcttga ctcaagaacg ttacgatcgt
    20281 ttgaaagaaa cagcaatcct catgcaccca gctccaatca atcgtgatgt agaaatagca
    20341 gaccacttgg ttgaagcacc aaaatcacgg attgtccaac aaatgaccaa tggtgtcttt
    20401 gttcgaatgg caatcttaga atccgtacta gcgagtagaa acgccaacta aaacacaaga
    20461 cgttaaaaga cgccagtgag cgtccacgag aggtgaaaat atgacaaaaa gaattctagt
    20521 attagaagat ggcacagttt ttgaaggcaa ggccttcgga gcagatattg atgtaacagg
    20581 cgaaatcgtc tttaatacag ggatgaccgg ctaccaagaa tccattacag accagtctta
    20641 taatggacaa atcttgacct ttacttatcc tttggtcgga aactatggaa ttaaccgtga
    20701 tgattacgaa tctattattc caacttgtaa gggagttgtt gttttcgaag aagcgcgtag
    20761 agcaagcaac tggcgcaacc aaatgacctt ggatgaattt ttgaaagcca agaaaattcc
    20821 tggtatttca gggattgata cgcgtgcact taccaagatt attcgtaagc atggtactat
    20881 gcgagcaacc ttgactcatg ttggagatag tatggaccat gtgactgacc agctccaagc
    20941 aacagtattg ccgacagata atattaagca ggtttctact aaaacttcct atccagctcc
    21001 aggagttggt ttgagcgtgg tgttagtaga ctttggtctc aagcactcaa tcctacgtga
    21061 actttctaag cgcaactgta atgtgacggt tgttccttat tcgacaacgg ctgaagaaat
    21121 tctccatctc aatcctgacg gagtgatgtt gtcaaacggt ccaggtaacc cagaagatgt
    21181 tccacaggca ctggatatga ttcgcggtgt acaaggaaaa attccaatct ttggtatctg
    21241 tatgggacat caactctttg ctatggcaaa cggggctaag acctataaga tgaagtttgg
    21301 ccaccgtgga ttcaaccatg cggtacgtga aatcgcaaca ggacgagtag acttcaccag
    21361 ccagaaccat ggttatgcag tcagccgcga ggatttgcca gagcacttga ttattaccca
    21421 cgaagaaatc aatgacaagt cagtggaagg tgtgcgccac agataccaac ctgctttctc
    21481 tgttcaatac cacccagatg cagctcctgg gccacacgac gctagctacc tatttgacga
    21541 gtttatcgag atgatggaag tttttaaaca atcaaactaa gaacgagtaa aagctcgtcg
    21601 gagaatttat gtaactgaac acggacggaa agctcagaat ttagagaaac caacttggat
    21661 tgtcaatcct tccttgattt cttaaaattc aatcgctttc tattcgtcct ttgtatctta
    21721 tttaatgtcg ccctgagagg cgacgaatag aaaggagaag ggtgctccgt atttgctgaa
    21781 ctgaatacgg gctacggacg gtgctaaaaa gatagttatt cctagaactg acagttcttc
    21841 gtcataactc ctattttagc tttgtccgct tgacgccctt aatatcttat atatgcctaa
    21901 acgtactgat attcaaaaaa ttatggtgat tggttctggt ccgattatta ttggtcaggc
    21961 tgctgagttt gactatgctg ggacccaggc ttgcttgtcg ttgaaagagg aaggttatga
    22021 ggttgttttg gttaactcaa atcctgcaac catcatgacg gacaaggaaa ttgctgacaa
    22081 ggtttacatt gaaccgatta cacttgagtt tgtgacacgt attcttcgta aggaacgtcc
    22141 agatgccttg ctaccaacac tcggtggtca gacaggtctc aacatggcca tggaattgtc
    22201 taaaaatggt atcttagatg agcttagcgt tgaacttctg ggtactaaat tgtctgccat
    22261 tgaccaagcg gaggaccgtg acctctttaa acaattgatg gaagagcttg agcaacccat
    22321 tccagaatct gaaattgtta acacagtaga agaagcagtt gcctttgcag cgacaattgg
    22381 ctacccagtc atcgttcgtc cagcctttac ccttggtggt actggtggtg gtatgtgtgc
    22441 caacgagaaa gaattgcgtg aaatcactga aaatggtttg aaattgtcac ctgttaccca
    22501 atgtttgatt gagcgttcga ttgctggttt caaggaaatt gaatacgaag tgatgcgtga
    22561 ctcagctgac aatgccttgg ttgtttgtaa catggaaaac tttgacccag ttgggattca
    22621 cacgggggat tccattgtat ttgcccctgc gcaaaccatg tcagactatg aaaaccaaat
    22681 gcttcgtgat gcgagcttga gcattattcg tgccctcaag attgaaggtg gatgtaatgt
    22741 tcagctagct cttgatccta acagcttcaa gtattatgtt atcgaagtaa accctcgtgt
    22801 atcacgttcg tcagcccttg cttctaaagc gacaggatat ccgattgcta agttggctgc
    22861 caagattgca gtaggtttga ccttggatga ggttataaac ccagttacag gttcaaccta
    22921 tgccatgttt gaaccagccc ttgactacgt agttgctaag attccacgtt tcccatttga
    22981 caagtttgaa aagggtgaac gccgtctcgg tacacaaatg aaggcgactg gagaagtcat
    23041 ggcaatcggt cgtaacatcg aggaatctct tctcaaggcc tgccgctccc ttgaaattgg
    23101 ggtgcaccac aatgaaatac ctgaacttgc agcagtttct gatgatgcct tgattgaaaa
    23161 ggttgtcaaa gcccaagatg accgtctctt ctacgtatca gaagcaattc gtcgtggcta
    23221 cacacctgaa gaaattgcag agcttacaaa aattgatatc ttctatcttg ataaactctt
    23281 gcatatcttt gaaattgagc aagaattggg tgctcatcca caagatctag aagttttgaa
    23341 aacagccaaa cttaatggtt tttcagaccg taagattgct gaactctggg gaacgactga
    23401 tgataaagtt cgccaacttc gcttggaaaa caagattgtt ccagtttata agatggtaga
    23461 cacttgtgcg gcagagttcg actccgaaac gccatatttc tattcaacct atggttggga
    23521 aaatgaatct atcagatctg ataaagaatc tgtacttgtc ctaggttcag gtccaatccg
    23581 tatcggtcaa ggggttgagt ttgactacgc aaccgttcac tctgttaagg ctatccaggc
    23641 agctggttat gaagctatca tcatgaactc aaacccagag accgtttcaa cagacttctc
    23701 tgtatcagat aagctttact ttgagccatt gacattcgaa gatgttatga acgtcattga
    23761 cttggaacaa ccaaagggag ttatcgttca gttcggtggt caaacagcca tcaaccttgc
    23821 ggagccattg gcaaaagcag gtgtgaccat ccttggtaca caggttgctg acctagaccg
    23881 tgccgaagac cgtgacctct tcgagcaagc tctcaaagaa ttggatattc cacagccacc
    23941 aggacaaacg gctaccaatg aagaagaagc agctcttgca gctcgtaaga ttggcttccc
    24001 agttcttgtc cgcccatctt atgtacttgg tggacgtgcc atggaaatcg ttgaaaacga
    24061 agaagacctt cgttcttaca tgcgaactgc tgttaaggct agtccagatc acccagttct
    24121 tgtcgactct tatatcgttg ggcaagagtg cgaagttgat gccatttcag atggtaaaga
    24181 tgtgctcatt cctggtatca tggagcatat cgaacgtgct ggtgtccact caggtgactc
    24241 aatggctgtt tacccaccac aaaccttgtc gcaaaaggtt caggagacca tcgcagacta
    24301 caccaaacgc ttagcaatcg gtcttcactg ccttggaatg atgaacatcc agtttgttat
    24361 caaggatgaa aaagtctacg ttattgaggt caatccacgt gccagccgta ctgttccatt
    24421 cctatctaag gtaaccaata ttcctatggc tcaagtagcg accaagctca ttcttggtca
    24481 aagtttatca gaacttggct accaaaatgg actttaccct gaaagcaccc gtgttcatat
    24541 caaggcacct gtcttctcct ttaccaaact agctaaggta gacagcttgc tcggtcctga
    24601 aatgaagtca acaggtgaag ttatgggttc tgatgctact ttggaaaaag ctctctataa
    24661 agcctttgaa gcttcttatc tacacttgcc aacttttggt aatgtcgtct ttaccatcgc
    24721 tgatgatgcc aaagaagaag ccttgaactt ggctcgtcgt ttccaaaaca ttggttatgg
    24781 aatccttgcg acagaaggga cagcagcctt ctttgctagt catggcttgc aagcccaacc
    24841 tgttggtaag attggtgatg acgataagga tatcccaagt tttgtacgca aaggaagaat
    24901 tcaagctatc attaacacag taggaacaaa acgaactgct gacgaagatg gtgagcaaat
    24961 tcgtcgttca gccattgaac acggggtgcc cctcttcaca gcgctagata cagctaatgc
    25021 catgcttaag gtacttgaaa gtcgtagctt tgttacagaa gcgatttaaa tagaaaaata
    25081 agatatagca gactgaattt agaacagtac acaggaatac taaaatattt ctataaatta
    25141 atttgaattt tctaattgat ttgttcgcat cttatttcaa tctactatag aaaaaagtct
    25201 ttaaaattat aaaacgcatc atatcaaggt ttttcaaaaa ccttgatatg atgcgtttta
    25261 ttgtgggaat atgtatttca ttttctacta aaattatgtt tttgaataac ctctatctta
    25321 gtagtttgta taatccccct caatcagttt ttgcgataag ctttaatgct atgactatac
    25381 cactcttgca tttcttttga tggtggtgtc atataatcgc catacatctg ggttaaaaat
    25441 tggtcatatt ttttgggaac aggcaacata cggccctcaa actcagttaa aatcagttct
    25501 ttaaaggtat caactgggaa gatttctttc atcccttcct taccgatccc aactcctcct
    25561 tcatattgag gaatgttggt tacagcattt ttgactagtt gatcaatttt cttgtaaaag
    25621 tagcgaggat tgacaaatcg gagagcgtac cagctacata atctaagaaa atcttttagt
    25681 ttgctatcac cgtgaactgc tcgtgatttt ttgatataag ctagttgacg aagagccaca
    25741 tacttatagc tcttgtcgac aatgctcaag tctgtaaatc gatcaattgg gaagacatcg
    25801 atgaaaaggc tggtatcatg acgcttgtac ttaacatggt cttctataac agtagaagtg
    25861 tccaaaatcg atgcgaaatt atggaagtac caagaagatg tatcgtagga aagaaccttg
    25921 tagcgagggt gattttcttc ttcaataatc ttcagtaaac gctcataatc ctcacgataa
    25981 agggaaatat caatatcatc atcccaagga atcatacctt tgtggcggat ggctccaagc
    26041 atggttccat aactgagaaa ataaggaata tcatgtttct tacaagtctc atcaatatag
    26101 tccagcaggg ctagttgaat ttctttaatt tctttttttt ctaaatattg catcctaatc
    26161 ctccaattta taagcgtgaa attcatgact gtagaagcgt ttttcttctg gtggtagggt
    26221 catataatct ccataaaatt gtgtcaaaat agtatcaaat ttttcaggtg caggaaggct
    26281 taaattctca aagggtaaat cgattgtttt atcaaaggta ccacttggga agacttcctt
    26341 ttccttaaat tttgaaggga taaaagccat atactgccca ttttcacgac tatatttttg
    26401 aatttctttc tcgattttat ttgcaaaata acgaggagaa actggtcgaa ggagcaacca
    26461 aaaggctgtt cgtatccaat cttttaaaag gctatcctta tagacaatat ttttatgttt
    26521 actgaaagac agcagtttga agctttccag tttataacaa gtatcaatga ccttaggatc
    26581 atcaaagcga tctataggga aaatatcgat aaagatacca gactcatagg tttttgtatt
    26641 tcgagtatca ataattttag tcgtactgtc ggttatcttg ataaagttgt taaagtagtt
    26701 cttatcagtt tctaaggata ggagcttata cttgcttttt tccttttgaa aaatgttaat
    26761 aaatcgttgg tagtcttctc taggcatgga taaatcaata tcgtcgtccc aagggataaa
    26821 gccctcatgt cgaaccgccc caatcagagt accgtagtta ataatatagt tgatattgtg
    26881 ctttttacag agagtatcaa tataatccaa aatttctaat tcaatttgtt tggcatcttc
    26941 aatggttagt tgtttcattt taaactccta tgattttttg aatttatttt ttaaggctag
    27001 gacatggttt aaaaattcat agaaaatgct atcttttgtg aagacaagta gactaatata
    27061 agagatagct gatagcaaga caatcaaacc agtattaatt aaaaatggca aattaatgac
    27121 catatccaca ggatacacga aattaatcag gaaataaatt gctacaaagg aaagtgaaaa
    27181 gagagagtat cgaacagtat agctaaagat atgtcccaag tggatgagtt gttttctatg
    27241 gatgaaaata atatagaaaa caagtagaga agtctctgat aacatagttg tcagtaagta
    27301 gtattcagga accacgatat ggttgaaaaa gaggagacta ttcaagccca aattgagtag
    27361 cccagcaaag actgtataga ctgtgatacg tttttcatag ccattggtaa agagaatttg
    27421 ggaaccaaga atggtatcta aggccaggat aatcgtacga aaagcgaaga gagaggtcaa
    27481 gatgccgcct ccgatatatt tttcactacc gtaaagtagg atggcatttg gtcctaaaac
    27541 catgagtcca aaactcagtg gaatgataaa gaagttaaag attcgactac ctctattaac
    27601 cagagaaaca taggcttctt tgtctccttt ccccagatag taactgagac gaggcacact
    27661 cactccaatt gcacctgtta caaccccagc tataacggtc acaattcgct gagctatggt
    27721 atagtaacta acgttgacat caatccctgt tttaacgagg aagaggcgat ctaaaaaagt
    27781 gaagagcata ttggcattgg caaagactaa catggctgtc agagggagaa agagtggttt
    27841 aaaatcactt aggtgaatct taacaagttt gatgtctctt ttaatccaaa aataactaat
    27901 caggtagtta atcagcgtcg ataaactcat cacaagtgta tagacaacaa tatcgtgttc
    27961 atttttaaca aataagaaaa tagagaccag catcaggata cggatgaagg cagttttgta
    28021 aaagagaaaa ctgtaatttt ccagagcttc attgacccat tcgattgaaa aaatctgggc
    28081 aatgagttga atccccataa caaggtagac ctttttgacg attggattat caataaagaa
    28141 gagaggatag gctaggatat agacagcagt ggtcaaaatc gtacaagcga tgcacaaata
    28201 aaaaagacta gaaaaggttc tgttaagatc ttttttgtta tccttgacat tactgatagc
    28261 ccttaaaccg tagttataga caccataagt tgcaaagggc aagaaaaatg acaaaatagt
    28321 gtcgactgag ttgaagtaac catagtcagt tcggtccaag acacgcgcga cataggttcc
    28381 agttaggatg ggaaaaataa tattcaagac acgaattccc atgtaagata gagcatttaa
    28441 ttttatactt ttcattcaat ttacctcgtt tttcattata tcataaagtt agctaataag
    28501 aaatgaaggg cagtaagtca agtaatcact ttgaagtttc aaatcttaag ttttaagttt
    28561 tctttaagga aagtatatta ttctgaagga ctctaaaatt tcgcagccat ttattagtaa
    28621 ttgctacaga attcctagtc attactagaa atggactagt ttctttgaat aatagaactg
    28681 cataattctc ctattctaga aggggaggac cagtatttct tttatgatag gactagattg
    28741 tggtataata gagagaataa gtttttttag taagacaaag gagaaaatag atgatttatg
    28801 caggaattct tgccggtgga actggcacac gcatggggat cagtaacttg ccaaaacaat
    28861 ttttagagct aggtgatcga cctattttga ttcatacaat tgaaaaattt gtcttggagc
    28921 caagtattga aaaaattgta gttggtgttc atggagactg ggtttctcat gcagaagatc
    28981 ttgtagataa atatcttcct ctttataagg aacgtatcat cattacaaag ggtggtgctg
    29041 accgcaatac aagtattaag aaaatcattg aagccattga tgcttatcgt ccgcttactc
    29101 cagaggatat cgttgttacc cacgattctg ttcgtccatt tattacactt cgcatgattc
    29161 aggacaatat ccaacttgcc caaaatcatg acgcagtgga cacagtggta gaagcagttg
    29221 atactatcgt tgaaagtacc aatggtcaat ttattacaga tattccaaat cgtgctcacc
    29281 tttatcaagg acaaacacct caaacattcc gttgcaagga cttcatggac ctttatggat
    29341 ctctttctga tgaagagaag gaaatcttga cagatgcatg taaaatcttt gtgatcaaag
    29401 gaaaagatgt ggccttggcc aaaggtgaat actcaaatct gaagattaca accgtaacag
    29461 atttgaagat tgcaaaaagt atgattgaga aagactagta aaatgattaa tcaaatttat
    29521 caactaacta agcctaagtt tatcaatgtc aaatatcagg aagaggctat tgaccaagag
    29581 aatcatatcc ttatccgtcc caactacatg gctgtctgtc atgcggatca gcgttactat
    29641 cagggaaaac gtgatcccaa gattttgaat aaaaagcttc caatggcaat gattcacgag
    29701 tcatgtggaa ccgtcatttc tgacccgacc ggaacctacg aggttggtca aaaagttgtc
    29761 atgattccca atcagtctcc tatgcagagt gatgaagaat tctatgaaaa ctacatgaca
    29821 gggacccatt tcttgtctag tggatttgat ggctttatga gagagtttgt ttctctccct
    29881 aaagatcgtg tggtggctta tgatgctatt gaagatacgg ttgcagccat tacagagttt
    29941 gtcagtgtgg gcatgcacgc tatgaatcgt ctattgactc ttgctcatag caagcgggag
    30001 cggatcgccg ttattggaga tggaagttta gcttttgtgg ttgccaatat tatcaactat
    30061 actttgccag aatcagagat tgtggttatt ggtcgtcatt gggaaaagtt ggaactcttc
    30121 tcatttgcca aagaatgcta tattacggat aatattcctg aagagttggc ctttgaccat
    30181 gcttttgaat gttgtggtgg tgatggtact ggaccagcta ttaatgactt gattcgctac
    30241 attcgtcctc agggaacgat tctcatgatg ggagttagcg aatataaagt caatctcaat
    30301 actcgcgatg ccttagaaaa gggcttgatt ttggttgggt catctcgttc tggtcgcatt
    30361 gattttaaaa atgctatcca aatgatggaa gtcaagaaat ttgccaatcg tcttaaaaat
    30421 atcctttatc tagaagaacc tgtaagagaa attaaagata ttcatcgtgt ctttgcaacc
    30481 gatttaaaca cagcctttaa aacagtgttt aagtgggaag tataagtact ggaggttaat
    30541 tgtggagaaa atcattaaag aaaaaatttc ttccttactt agtcaagaag aggaagtcct
    30601 cagtgttgaa caactgggtg gaatgaccaa tcaaaactat ttggccaaaa caacaaataa
    30661 gcaatacatt gttaaattct ttggtaaagg gacagaaaag cttatcaatc gacaagatga
    30721 aaagtacaat cttgaactac taaaggattt aggcttagat gtaaaaaatt atctttttga
    30781 tattgaagct ggtatcaaag taaatgagta tatcgaatct gcgattacgc ttgattcaac
    30841 gtcaatcaag accaagttcg acaaaattgc tccaatatta caaactattc atacgtctgc
    30901 taaggaatta agaggagaat ttgctccttt tgaagaaatc aaaaaatacg aatccttgat
    30961 tgaagaacaa attccttatg ccaactatga atctgttaga aatgcagtct tctccttaga
    31021 gaaaagactg gctgacttag gtgttgacag aaaatcttgt catatcgatt tggtgcctga
    31081 aaactttatc gaatcacctc aaggacgact ttatttgatt gactgggaat attcatcaat
    31141 gaatgatcca atgtgggatt tggctgccct ctttttagag tctgaattca cttcccaaga
    31201 ggaagaaact ttcttatctc actatgagag tgaccaaaca ccggtttctc atgaaaagat
    31261 tgctatttat aaaattttac aagatactat ttggagtcta tggactgtct ataaggaaga
    31321 gcaaggtgaa gattttggtg actatggtgt gaatcgttac caaagagctg ttaaaggttt
    31381 ggcttcttat ggaggttcag atgaaaagta aaaacggagt tccttttggc cttctctcag
    31441 gtattttctg gggcttgggt ctaacggtta gtgcttatat cttttcgatt tttacagatt
    31501 tgtcaccctt tgtggtggct gcagctcatg attttttgag catctttatc ttactagctt
    31561 ttctcttggt aaaagaaggg aaagttcgcc tctcaatttt cttaaatatt cgcaatgtca
    31621 gtgttatcat cggagccttg ctagcaggcc ctatcggtat gcaggccaat ctttatgcag
    31681 ttaagtatat cggaagttct ttagcttcat ctgtatcggc tatttaccct gcgatttcag
    31741 ttctattggc tttcttcttt ttgaagcaca agatttcgaa aaatactgta tttgggattg
    31801 tcttgattat tggagggatt attgcccaga cctataaggt tgaacaggtt aattccttct
    31861 acattgggat tctctgtgct ttggtttgtg ctattgcatg gggaagtgag agtgttctta
    31921 gctcctttgc tatggaaagt gaactgagtg aaatcgaagc cctcttaatc cgtcaagtga
    31981 cttcgttctt gtcctatctt gtgattgtgc tcttctctca tcagtcattt actgcagtag
    32041 ccaatggaca attgctaggt ctcatgattg tttttgcagc ctttgatatg atttcctact
    32101 tggcttatta tatcgctatc aatcgcttgc aaccagccaa ggctacaggc ttgaacgtga
    32161 gctatgtagt atggacggtc ttgtttgcag ttgttttttt gggtgcaccg ctagatatgc
    32221 tgaccattat gacgtcactt gtcgtcattg ctggagttta tattattatt aaagaataaa
    32281 ggagattcgt gtgaaagcca ttatcttagc agcgggattg ggaactcgct tgcgtcctat
    32341 gactgaaaat acccctaaag ccttggttca ggttaatcaa aaacctttga ttgaatacca
    32401 aattgagttt ctcaaagaaa aaggaatcaa tgacatcatc atcattgttg gttatcttaa
    32461 agaacaattc gattacttaa aagaaaaata cggtgttcgc ctcgttttca atgataaata
    32521 cgctgactac aataactttt actctctcta tcttgtaaaa gaagaattgg ccaacagcta
    32581 tgttattgat gctgacaatt atctctttaa aaatatgttc cgcaatgatt tgacacgttc
    32641 gacttatttt agtgtttatc gtgaagattg taccaacgaa tggttcttgg tctatggaga
    32701 tgactacaag gttcaagaca ttattgttga tagcaaggca ggtcgcatcc ttagtggtgt
    32761 atccttctgg gatgctccaa ctgcagaaaa gattgtcagc tttatcgaca aggcttatgc
    32821 aagtggtgaa tttgttgatc tctattggga caatatggtt aaggataata tcaaagagct
    32881 agatgtctat gttgaagaat tagaaggcaa tagcatttat gagatcgata gtgtccaaga
    32941 ctatcgtaaa ttagaagaaa ttcttaaaaa cgaaaattaa agattccaac atctgacaaa
    33001 atagtcggat gttttttgat tttttacgaa cttttacgaa tagatagatg agtagaaaaa
    33061 gaaatggagt tatttatgaa aatcacaaac tatgaaatct ataagttaaa aaaatcaggt
    33121 ttgaccaatc aacagatttt gaaagtgcta gaatacggtg aaaatgttga tcaggagctt
    33181 ttgttgggtg atattgcaga tatatcaggt tgccgtaatc cagccgtttt tatggaacgt
    33241 tattttcaga tagacgatgc gcatttgtcg aaagagtttc aaaaatttcc atctttctct
    33301 attttagatg actgttatcc ttgggatttg agtgaaatat atgatgcgcc tgtactttta
    33361 ttttacaagg gaaatcttga cctcctgaaa ttcccgaagg tagcggtcgt gggcagtcgt
    33421 gcttgtagca aacagggagc taagtcagtt gaaaaagtca ttcaaggctt ggaaaatgaa
    33481 ctggttattg tcagtggtct ggccaagggc attgacacag cagctcatat ggcagctctt
    33541 cagaatggcg gaaaaaccat tgcagtgatt ggaacaggac tggatgtgtt ttatcctaaa
    33601 gccaataaac gcttgcaaga ctacatcggc aatgaccatc tggttctaag tgaatatgga
    33661 cctggcgaac aacctctgaa atttcatttt cctgcccgta atcgcatcat tgctggactt
    33721 tgtcgtggtg tgattgtagc agaggctaag atgcgttcag gtagtctcat tacgtgtgag
    33781 cgagcaatgg aagaaggacg cgatgtcttt gctattcctg gtagcatttt agatggacta
    33841 tcagacggtt gccatcattt gattcaagaa ggagcaaaat tgctcaccag tgggcaagat
    33901 gttcttgcgg aatttgaatt ttaaaaatga cctaagctag aattctaaga aaaaatcaat
    33961 tttaagagaa aatgaaccca acatttccat aataaaacgc atattagcaa gtttttaaca
    34021 cttgctaata tgcgtttttt ctaagtggat tagtagagta gaggattttt ctcatataat
    34081 actcttcgaa aatctcttca aactacgtca gcttccatct gcaacctcaa aacagtattt
    34141 tgagctgagt tcgtcagtct tatctacaac ctcaaagcag tgctttgagc aacctgtggc
    34201 tagcttccta gtttgcgctt tgattttcgt tgagtataag ggaaagtata gtgaattgaa
    34261 ataagatgtg aacaactcta tcaggaaagt caaattaatt tatagaaata ttttagcagc
    34321 caaggtgcac tgttatagat tcaatacact ataatttagt gtaattgaga aaggagaaat
    34381 gattgtgatt gatgttggct aggttatgtt caatgattcc taccatctca aatcttgtta
    34441 gtaaggaaaa ataaattctt caaaagtaga gattacaagg cttgtttaag aaagaattca
    34501 aagaccttga caaataaaaa taaaatggtt attataaaaa atggtctgaa atagatgatg
    34561 atacttttcg aaaatctttt tacgtcagct cagctttgcc ttgctgtgtt ttgagcaagc
    34621 tacggttagc ttccgagttt gattttcatt tactagaaat gaaactgatg agagatatca
    34681 gtagacattt gagtcaggat attatggaaa atgataaaaa gagctcgtga gattggcata
    34741 tcagactact aaagtattga gtttgttagg attttagcga ctagttagct gggaaaggaa
    34801 gatatttgtg acaaataata aactgtattc gttgatagaa tttagaaata aaatatatga
    34861 agaattagaa ctttccagaa gtgatttagc gattttacta tgtgccatgc ttatcgcctc
    34921 tatcggatta aatatggatt cgactcccgt gattattgga gccatgttaa tctctccttt
    34981 gatgacacct attctgggag tggggctctc tctagctata tttgatttta aattgttaag
    35041 aaaatctttt aaaatattag ctattcaaat tcttgccagt ttaatagctt caacacttta
    35101 tttttatctt tctcccattt cgtatgctag ttcggaaatt gttgctagaa cctctccgac
    35161 tatttgggat gttctcattg cttttgtagg agggatagca ggtattattg gtgctaggaa
    35221 aaaagagacc aataatattg ttcctggtgt tgctattgca accgccttga tgcctcctct
    35281 ttgtacagta ggttatgcta ttgcttctgc taatctaaaa tttatcatag gctcctctta
    35341 cctattcctc atcaattgta gctttattgt cattgcgact tatataggtg ttaggttgat
    35401 gatggttaag aaacattatt ttaaagataa tgaagaagac tctaaaatgc gtaggatttt
    35461 gcttctagtt gctgttttgc tgatgattcc gagtttcatc tctgcaacga ctttagtgag
    35521 agaaacgttg aaaaaagagt cccttaagaa atttatatca gagcagtttc aggggtataa
    35581 tattttgaaa aaaacctatt ctaaaaagac tcatacccta aagctaacca tttcaggaaa
    35641 ttatttgaca gaagaagaac tcgatatgat ttcaagtaag agaggtgact atggtttaag
    35701 tgatgtttct gttcaagttt cacaattgtc tgattcagaa caacttagta aggaagagct
    35761 ggtggagcat ttcttccagt atatcaagga taaggaagca aaagaaaagg agaaagccaa
    35821 taaatttgat acagagtctg aggagcaata atttcttgag aatagctggt ttctctcgtg
    35881 agtcttctat gtatatcaaa ggaagactga ggttttaagt ataaaacttt tcttctatta
    35941 tagtagctaa gtcttgacag ggttcaaaaa atggtttaca ctttataaag tttattactt
    36001 tgaaaaggtg tgatactgtg gctacggcaa caaaaaagaa aaaatcaaca gttaaaaaaa
    36061 atctagtcat cgtggagtcg cctgctaagg ccaagacgat tgaaaaatat ctaggcagaa
    36121 actacaaggt tttagccagt gtcgggcata tccgtgattt gaagaaatcc agtatgtccg
    36181 tcgatattga aaataattat gaaccgcaat atattaatat ccgaggaaaa ggccctctta
    36241 tcaatgactt gaaaaaagaa gctaaaaaag ctaataaagt ttttctcgcg agtgacccgg
    36301 accgtgaagg agaagcgatt tcttggcatt tggcccatat tctcaacttg gatgaaaatg
    36361 atgccaaccg tgtggtcttc aatgaaatca ccaaggatgc agtcaaaaat gcttttaaag
    36421 aacctcgtaa gatcgatatg gacttggtcg atgcccaaca agctcgtcgg atcttggatc
    36481 gcttggtagg gtattcgatt tcgcctattt tgtggaagaa ggtcaagaag ggcttgtcag
    36541 caggtcgcgt tcagtccatt gcccttaaac tcatcattga ccgtgaaaat gaaatcaatg
    36601 ccttccagcc agaagaatac tggacagttg atgctgtctt taaaaaggga accaaacaat
    36661 ttcatgcttc cttctatgga gtagatggta aaaagatgaa actgaccagc aatgacgaag
    36721 tcaaggaagt cttgtctcgt ctgactagta aagacttttc agtagatcag gtggataaga
    36781 aagagcgcaa gcgcaatgct cctttaccct ataccacttc atctatgcag atggatgctg
    36841 ccaataaaat caatttccgt actcgaaaaa ccatgatggt tgcccaacag ctctatgaag
    36901 gaattaatat cggttctggt gttcaaggtt tgattaccta tatgcgtacc gattcgactc
    36961 gtatcagtcc tgtagcgcaa aatgaggcgg caagcttcat tacggatcgt tttggtagta
    37021 agtattctaa gcacggtagc aaggtcaaaa acgcatcagg tgctcaggat gcccatgagg
    37081 ctattcgtcc gtcaagtgtc tttaatacac cagaaagcat cgctaagtat ctggacaagg
    37141 atcagctcaa gctatatacc cttatctgga atcgttttgt ggctagccag atgacagcgg
    37201 ccgtttttga taccatggct gttaaattgt ctcaaaaagg ggttcaattt gctgccaatg
    37261 gtagtcaggt taagtttgat ggttatcttg ccatttataa tgattctgac aagaataaga
    37321 tgttaccgga catggttgtt ggagatgtgg tcaaacaggt caatagcaaa ccagagcaac
    37381 atttcaccca accgcctgcc cgttattctg aagcaacact gattaaaacc ttagaggaaa
    37441 atggggttgg acgtccatca acctacgcgc caaccattga aaccattcag aaacgttatt
    37501 atgttcgcct ggcagccaaa cgttttgaac cgacagagtt gggagaaatt gtcaataagc
    37561 tcatcgttga atatttccca gatatcgtaa acgtgacctt cacagctgaa atggaaggta
    37621 aactggatga tgtcgaagtt ggaaaagagc agtggcgacg ggtcattgat gccttttaca
    37681 aaccattctc taaagaagtt gccaaggctg aagaagaaat ggaaaaaatc cagattaagg
    37741 atgaaccagc tggatttgac tgtgaagtgt gtggcagtcc aatggtcatt aaacttggtc
    37801 gttttggtaa attctacgct tgtagcaatt tcccagattg ccgtcatacc caagcaatcg
    37861 tgaaagagat tggtgttgag tgtccaagct gtcatcaggg acaaattatt gagcgaaaaa
    37921 ccaagcgtaa tcgcctattc tatggttgca atcgctatcc agaatgtgaa tttacctctt
    37981 gggacaagcc tgttggtcgt gactgtccaa aatgtggcaa cttcctcatg gagaaaaaag
    38041 tccgtggtgg tggcaagcag gttgtttgta gcaaaggcga ctacgaggaa gaaaagatta
    38101 aataagagga ggggcccgaa agtaaatttc aggctccttt tggttagaac ttgacaaaat
    38161 acatcatttt atgcgaaact agaagaagat tattttatac tcaatgagaa tcaaagagca
    38221 aattagaaag ctagtcgcag gttgctcaaa gcactacttt gaggttgaag atggaagctg
    38281 acctggtttg aagagatttt cgaagagtat taactaggag aagttatgcg tcttatctat
    38341 ctaattattg gttttttatc gctggccttg gctattgttg gggttgtttt acccttgttg
    38401 ccgacaacgc ctttcctttt gttgtctatt gcttgtttct ccagaagttc caagcgtttc
    38461 gaagactggc tttatcatac caagctctat caaacatatg tagctgattt tcgcgagact
    38521 aagtctatta cgcgtgaacg aaagaaaaaa atcatcgtct ctatctacgt cttgatggga
    38581 atttctattt attttgcacc tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc
    38641 tttatcactt attatctctt caaggtcatt ccagacaaag aatagttaaa acagtagtta
    38701 tttgccttga taaaattgaa agcatattca taacaatatg atataataaa tttgaagtaa
    38761 tattcaagga gaatcaaatg atttacgaat tttgtgctga aaatgtgact ttacttgaaa
    38821 aagcgatgca ggctggagct cgtcggattg aactctgtga taatctagca gttggtggga
    38881 caacacccag ctatggagtg actaaggcag cggttgaact ggcagctaac tacgatacaa
    38941 ccatcatgac catgattcgg ccacgtggtg gtgactttgt ctataatgac ctagaaattg
    39001 ctatcatgct agaagacatt tgtttgactg ctcaggctgg aagtcaaggg gttgtatttg
    39061 gagctttaac tgctgataaa aagttggata agcctaatct ggaaaagtta attgctgcat
    39121 caaaaggaat ggaaattgtc tttcacatgg cctttgatga actaagtgat gaagatcaac
    39181 cggaagctat tgactggctc agtcaagccg gtgtcactcg tatcctaact cgtgctggtg
    39241 tgtctggcga ctccttagaa aaacgttttg ttcactatca cagaattttg gagtacgcta
    39301 aaggtaaaat tgaaattcta ccaggtgggg ggattgacct tgacaaccgt caaaccttta
    39361 ttgaccaggt gggggtaaca caattgcatg gcactaaggt tgttttttaa aaaatagaaa
    39421 ggaactgcta gccttgggta gcagttttca cttatgtttg aaatttttaa atcctatcaa
    39481 tttaatcaag aaaaggctca tgattatggt tttatagaaa atagcgaagt ctggacatat
    39541 agttgccaga ttttgcaagg tgactttgtc atgactgtgt ccatcactgc tgataatgtg
    39601 aactttcaag tctttgacca agagactggt gacctctatc ctcacgttca tatggaaagc
    39661 atgaggggaa gttttgtcgg aaatgtccgt gaggcttgtc tggagattct ttaccagatt
    39721 cggaaggctt gttttgatgt gcaagatttt atctgtcatc agactaagcg tatcatgact
    39781 caagttcagg aaaagtatgg aaaccagttg gagtatctgt gggaaaaatc gcctgataca
    39841 gctgtattgc gccatgaagg caatcaaaag tggtatgccg tcttgatgaa aatctcttgg
    39901 aataagctgg aaaagggcag agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa
    39961 gtagctaatt tgctttcaca aaaggggatt tatccagcct tccatatgag caagcgctac
    40021 tggattagtg tgtcccttga tgatacttta tcagatgaag aagtactgga attgatagaa
    40081 aaaagttgga acttaacctc taaaaaatga aatattttaa taattttcat gaactttcaa
    40141 ttagctaaat attctttact gaagaaattt tcagaaaata taggatttac cacaccagag
    40201 gaatgtggtg ccatcttcaa atacctgatt gagaatgtca agacggatcg tcagatcatc
    40261 tattcgcctc actgtcatga tgacctcgga atggcagtgg caaatagcct tgctgctgtc
    40321 aagaatggtg caggacgtgt tgaagggact atcaatggta ttagggagcg agctgaaaat
    40381 gctgctttgg aagaaattgc agtggctctc aatattcgcc aagattacta ccaagtagaa
    40441 accagtattg tcctaaatga gaccatcaat acgtcagaaa tggtttctcg cttctctggt
    40501 attccagttc ctaaaaacaa agccgtcgtt ggtggcaata ccttctccca cgaatctggt
    40561 attcaccaag atggagtcct taaaaatcct ctcacttatg agatcatcac acctgaattg
    40621 gttggtgtta agattccgct tggaaaatta tctggtcgcc atgcttttgt tgagaaactg
    40681 agagaattgg ccctagattt tacagaagag gatatcaaac cactctttgc taagttcaag
    40741 gcactggccg ataagaagta agaaatcaca gatgcagata ctcgagcttt ggtagctgga
    40801 accatggttg aaaatccaga aggcttccac tttgatgatt tacaacttca aactcatgca
    40861 gataatgaca ttgaagcgct cgttagccta gccaatatgg atggtgagaa agtcgaattt
    40921 aatgcgacag ggcaaggttc cgttgaagca atctttaacg ctatcgataa gttctttaac
    40981 taatctgttc gtttggtgtc ctacactatc aatgcggtaa cagatggaat cgatgcccag
    41041 gatcgggttt tggtcactgt tgaaaacaga gatacagaaa ccatctttaa tgcagcaggg
    41101 cttgattttg atgtgttgaa ggcttctgct attgcctata taaacgctaa tacctttgtt
    41161 caaaaagaga atgcaggtga gatgggacgc agtgtttctt accacgatat gcctagtgtg
    41221 taaaggagaa ggctatggca aagaaaatag tagctctagt aggagacgga attggcccag
    41281 aaatcatgga ggctggttta gaagttctgg aggctctagc tgaaaaaaca ggttttgact
    41341 atgagattga cagacgaccg ttcggaggtg cagatattga tgcagcagga cctcccttac
    41401 ctgatgaaac ccttaaggca agtagggaag cagatgctat cctactagca gctatcggta
    41461 gtcctcagta tgatggagca gcggttcgcc ctgaacaagg cctgatggct ctccgtaagg
    41521 aactcaatct ttacgctaat attcgtcctg taaaaatctt tgacagtctc aagtatttgt
    41581 caccactcaa accggaacga atttctggtg tagactttgt cgtggtgcgt gaattgacag
    41641 gcgagattta ctttggagat catattcttg aagagcgcaa agcgcgtgat atcaacgact
    41701 atagctatga ggaagtggag tggattattc gcaaagcctt tgaaattgca agaaatcgca
    41761 gaaaaatcct tactagtatc gataagcaaa atgttctagc gacctcaaaa ctctggcgga
    41821 aagtagctga ggaagtcgca caggatttct cagatgtaac cttggaacac cagctggtag
    41881 actcagctgc tatgcttatg attaccaatc ctgctaagtt tgatgttatt gtaacggaga
    41941 atctttttgg agatatttta tctgatgaat caagcgtctt atctggtaca cttggggtta
    42001 tgccatcagc cagtcattct gaaaatggac caagtctcta tgaacctatt tacggttcag
    42061 cacctgatat tgcaggtcaa ggaattgcca atcctatttc catgatttta tcagttgcca
    42121 tgatgttgag agatagtttc ggaggttatg aggatgcaga gcgtatcaaa cgtgctgttg
    42181 agacaagtct ggcggcagga attttaacga gagatatagg aggtcaggct tcaacaaagg
    42241 aaatgacgga agctattatt gcaaggttat gaagttagac gaaaaaatta ctctagtcct
    42301 tttgatttgg aatgtcatca ttttcttgat ttatggcatt gacaaattca aggcaagaag
    42361 aagagcttgg cgcatccaag agaaaatctt actcatttta gcccttactt gtggtggttt
    42421 tggggcctgg ttagctggaa tcacttttca ccacaagact cgaaaatggt actttaaaac
    42481 agtttggttt cttgggatgg tgaccacact agtagcctta tattttattt ggaggtaatg
    42541 gatggcaggg tcttcgaggg aatacgctgc ttgggctcta gcggactatg gttttaaggt
    42601 cgtgattgca ggatctttcg gtgacattca ttacaataat gaactcaata atggcatgtt
    42661 gccaatcgtt cagcctagag aggttagaga aaagctagcc caactcaaac cgaccgacca
    42721 ggtaactgta gacttggaac aacagaaaat tatctcacca gttgaagaat tcaccttcga
    42781 gatagatagc gagtggaaac ataaactcct aaatagtttg gatgatatcg gtattacctt
    42841 gcagtatgaa gagttgattg ctgcttatga aaaacaacga ccagcctact ggcaggatta
    42901 gaaaaaatag aaaaggaaat atagtaaact gaaataagat gtaaacaaat gaattggagc
    42961 ttaacatcca tttccagcaa ttttttagaa actacagtgg actattctgg attcaacaca
    43021 ttataaaatt atgacaaaac acattcacaa gaaggctacg acattttaaa aggtgagggc
    43081 ggatgtatcg tttgccctac taaagttggt tacattatca tgaccagcga taaggcagga
    43141 cttgagcgta agtttgcagc caaagaacgt aagcgtaaca aaccaggtgt tgttctctgc
    43201 ggtagcatgg atgaactttg cgctttagcg caactcaacc cagaaattga agcattctac
    43261 taaaaacatt gggatgaaga tattcttctt ggttgtatcc ttccttggaa accagaagcc
    43321 tttgaaaaat tcaaagcata cggggatggc cgtgaagaac ttatgactga tgtacgtggt
    43381 actagctgtt ttgttatcaa gtttggaaaa gcagatgaac aattggctgc caagctttgg
    43441 gaagaaggta aaatggtcta cgcctcatct acttcaatga taaaacgatt gaaactcgct
    43501 atgagagcaa ggtgtaatgg tgtctatggt cgataagaac ggcaaactca tcccagaaca
    43561 aggaggagca cgttcaactt caccagctcc agttgtgatc cgtaaagggc ttgacattga
    43621 taaaatcatg atgcacctgt cagatacttt taactcatgg gactaccgtc aggttgagta
    43681 ttattaggat agagaagaag tctagtgtta aggacattac agctcataat actaggcttt
    43741 tttatagaaa ttcttttctt tttctatagg atatggtatt ctatgtagaa aatatatgtt
    43801 aataagtaat gccaatattt aaacatcatt agtaaaagga gttagattga tgaataaaag
    43861 aaaagttagt ttagaagatt tttataaatg gtatagtcta aataaagaaa agttattaaa
    43921 taaggcaact gttggtgaaa agtttaatga taaattaaaa gaagagtttc tccaggaatg
    43981 gcctttggat aggattttaa caatgtcaat cgatgaatat gtaataggaa agggacagca
    44041 aaataagtct ttatgctacg ctcttgagaa gggaaaatac aaaaatctat ttcttggaat
    44101 ttctggtggc tcagcttcaa aatttggtat ttattggaat aaaaaaacaa acaaatataa
    44161 agatcaagct aataatgaga tttcagagtt ggatcagcga ttttcaaaat taaaatcaga
    44221 tttgtatgaa attatcaaag aaggtattcg ttttaacttt gaaaatccta tttttgatat
    44281 gaaaagatca acaaatgaat ttattggtcg ttctgctatg gtgacaaaat tactttgtat
    44341 ctattctggg ggagatcctt tctttggtgt aaatattaat agtcagaaag aattttggaa
    44401 ccactttgtt tctcagacaa atcaaggtgg accttatctg caaaatcata aaataattga
    44461 actggtgtcc aaaacttatc ctgagttgga gccatcgaaa ttaggaacta tgctttttga
    44521 gtattctaag ctttttatgg aaaataagga agacaatagt acaatggatt catcaaacaa
    44581 ttttcgtcat caattaactc aatctctatt aaagtctcca aaccttatcc ttcgtggtgc
    44641 tcctggcaca ggaaagactt atcttgctaa agaaattgcc aaagaattaa cggatggcaa
    44701 cgaagaccaa atcggatttg tacaatttca cccatcctat gattatacgg attttgtaga
    44761 aggtttaaga ccagtatcaa atggggatgg agctattgag tttaggctac aggacggtat
    44821 ttttaaagat ttttgtcaga aagcaaaaga aacccaattg attggaggac aagataattt
    44881 tgatgaggct tgggattctt acttagaata tataaatgtt gctgaagaaa aagaatatat
    44941 aacaaaaaca tcttacttat ctgttaatag tagacaaaat ttgtcagtaa attatgatag
    45001 tggtgttcca ggatggtcac tacctagcaa atatgtttac gagttgtata aagataaaaa
    45061 ttataataag caagaatact acaaaagtgg tggaaaaact gtcctagaaa cattgagaaa
    45121 gagatttggt ttgaaagact atgtttcccc aacagaaatt gatactgata agaaattcgt
    45181 cttcatcatc gatgaaatca atcgtgggga gatttctaag atttttggcg aactcttttt
    45241 ctctatcgac cctggctatc gtggtgaaaa aggaagtgtt tctacccaat atgcaaatct
    45301 acacgaaact gatgaaaagt tctatatccc cgaaaatgtt tacatcatcg gaactatgaa
    45361 tgatattgat cgttcagtgg atacctttga ttttgctatg cgtcgtcgtt ttcgttttgt
    45421 tgaagttact gccgagggtc aagttggcat gttggataaa gagctgaata tccatgcaga
    45481 agaagcaaaa attcgtctaa gaaacttgaa cgctgctatc gaaaatgttc aggaattaaa
    45541 cagtcattat catattggac caagttattt tcttaagttg aaggatgtag attttgacta
    45601 tgaattactc tggtctgatt atattaagcc tctcctagaa gactacttgc gaggttctta
    45661 tgatgaggtt gaaactttgg aaactttgaa aaaagcattt gaactgacaa ataatgagca
    45721 aaaagatcag gcagtagctg atgacaatga aggtgatgaa aacgatgatg cggattactg
    45781 ataatcaaca caagattatt aaagaaaaat ttgttgaaga atatcctaaa ctaagcaatc
    45841 ttcttttaga cagaaccttg gaaagtctat cccaagatga acgtattttc atttttccaa
    45901 atgatttgac tcatactcct gatttggata aggaccaaaa gatttttgaa acagtcaatc
    45961 agaaaatcaa gacagggaac gtgattggtt ttcttggata tggtcaggaa agattaacga
    46021 tttcctcacg attttctgat gagagtaatg accatttttt gcattatctc ttaaacaagg
    46081 ttcttcatat caatctcact agtttagatg ttgctttgtc tcgtgaagag aggctttatc
    46141 aacttttggt gtatctcttt cccaagtatc tacaagctgc tattcgaaaa ggtctttata
    46201 aggaatatca tcgattttct cataacgaca gtaatgttaa gggagtgatt gatgtaagaa
    46261 gccatctcaa gaaaaatctt cctttcacgg gaaatattgc ctacgcaacg agagagttca
    46321 cctatgataa tcccctcatg cagttggtcc gtcacactat tgaatacatt aagaatcaga
    46381 aaagcattgg tcaaggggta ctagataatc tctcaactag tcgtgaaaac gtatctgaaa
    46441 tcgtgcgtgt aacgccctct tataaactag ctgatcgtgc taagattatt cggggaaatc
    46501 aatctaaacc tatacgtcat gcatactttc acgagtacag aaacttacaa gaactttgtc
    46561 tgatgatcct aaaccaagaa aagcacggtt tagggtatca agatcaaaaa atctatggta
    46621 ttctctttga tgttgcctgg ctttgggaag agtatgttta caccttgttg ccaaaaggtt
    46681 ttgtacatcc cagaaataag gataagacgg atggaatttc agtattttct gttgggaaac
    46741 gaaaagtata tccagatttt tatgacagag aacgaaagat tgttctagat gcaaaatata
    46801 aaaaactgga attgactgaa aaaggaatca accgtgagga cttattccag ctgatttcct
    46861 attcttatat tttaaaagct gagaaggctg gactgatttt tcctagtatg gagcagtcag
    46921 taaatagtga aataggaaaa gtagctggct atggagctca attgaagaag tggtctattc
    46981 gaatccctca gaatgcctca ttctatagta cattttgtaa aatgatggaa aattcagaag
    47041 aaaattttaa agcgattatt gatgaagaag tggggagaaa ataatttccc ctctttcttt
    47101 tatttttaac acaagtaaaa cccgaacgat atattttaat tcataaaata atttgacaaa
    47161 aactgtactt tggtttataa taaattaagg aaacgtcgga aaaggcgtag tgatgcaaga
    47221 gcataggtag gtcattacaa aagaaacgag acatcgatat gttaaatgaa tttccaattt
    47281 ttgattacga agatattcaa ttgattccaa ataaatgtgt cattaaaagc cgtgcagaag
    47341 cggatacaag tgtcacttta ggaaatcaca cctttaaact acctgttgtg ccagcgaata
    47401 tgcagacgat tttggatgaa aatgtagcag agcaactggc taaaggtggt tacttctaca
    47461 ttatgcaccg ttttgatgag gcaggacgca ttccttttat taaacgaatg cacgatcaag
    47521 ggctcattgc ttctatctct gtcggtgtta aggattatga gtatgatttc gttagacagc
    47581 tcaaagctga tgctcctgag tatatcacta ttgatattgc tcatggtcat gcggatagcg
    47641 tgatttctat gattcaacac atcaagaaag aattgccaga tacctttgtc attgctggaa
    47701 atgtgggaac accagaagct gtgcgtgaat tggaaaatgc tggtgcggat gctactaagg
    47761 tcggaatcgg tcctggtaag gtttgtatca ccaaggttaa gactggtttt ggtacaggtg
    47821 gttggcagtt ggctgctcta cgctggtgtg ccaaggctgc gcgtaaaccg attatcgctg
    47881 atggaggaat tcgtactcac ggtgatattg ctaagtctat ccgcttcggt gctagcatga
    47941 tcatgattgg ttccctcttt gcaggacaca ttgaaagtcc agggaaaacg attgaagtcg
    48001 atggtgaaca gttcaaagaa tattatggtt cagcctcaca atatcaaaaa ggtgcttaca
    48061 aaaatgtgga aggcaaacgt atcttgcttc ctgctaaagg tcatctgcaa gacactttaa
    48121 ctgagatgga acaagacctt caaagtgcta tttcttatgc aggtggacgt caggttgctg
    48181 accttaaaca cgttgattat gtgatcgtga aaaactccat ctggaatggg gatgcttccc
    48241 actaagacgg ggtctttgac caaaaaactt gttattagag caaatttctg ttataataaa
    48301 acaagtttcc acccttagtg taatggatat cacgtaagat tccggttctt gagatggggg
    48361 ttcgattccc tcagggtgga tgtaaacatc ctaaaaagcc tttaataggg cttttttctt
    48421 tatcctgacc caaatttgcc gctaaaactg agaatctctg tctaaagaat tcccaaatgc
    48481 tttccagtcc cgttttagag tgactcaggg ggcttttttt gatataataa aaaggactat
    48541 tatcagttag aaagaggttg gtatgaaaga attacaaact gtactaaaga atcattttgc
    48601 aatcgaattt gcagacaaaa atttactgga aactgccttt actcatacga gttatgccaa
    48661 tgagcaccgc ctcttaaaaa tttcacacaa tgaacgcttg gaatttttag gagacgctgt
    48721 tctacagtta ttgatttcag aatatctata taaaaaatat cctaaaaagc ctgaaggtga
    48781 cctatcaaaa ctccgtgcta tgattgtccg tgaggagagt ttagctggtt ttgcgcgtga
    48841 ttgccagttt aaccagttta tcaagttggg taaaggggaa gaaaaatcag gtggtcgcaa
    48901 tcgtgacacc attcttggtg atgcctttga agcctttctt ggtgcccttc ttttggataa
    48961 ggatgtggcc aaggtcaagg aatttatcta tcaagtcatc attcctaagg ttgaagcagg
    49021 cgagtttgag atgattacag actataaaac ccatctccaa gagttgcttc aggtcaatgg
    49081 tgatgtggct attcgttatc aggtgatttc tgaaacaggg cctgctcatg ataaggtctt
    49141 tgatgtagaa gttcttgttg aaggtaagag catcggtcaa ggccaaggtc gttctaagaa
    49201 attagcagag caggaagctg ccaaaaatgc cgttgagaag gggctggatt catgtattta
    49261 aaggaaatcg aaattcaggg gttcaagtct tttgctgata agaccaaggt cgtttttgac
    49321 caaggtgtga cggcagttgt tggacccaat ggatctggaa agtccaatat tacagaaagt
    49381 ctgcgttggg ctttggggga gtctagtgtc aagagtctcc gtgggggcaa gatgccggat
    49441 gtcatctttg ctggaaccga aagtcgcaaa ccgctcaatt atgcttctgt agttgtgact
    49501 ctggataatc atgacggatt tatcaaggat gcaggtcaag aaatcagggt ggaacgccat
    49561 atctatcgta gtggagatag cgaatacaag attgacggca agaaagtccg tctgcgtgat
    49621 attcatgacc tcttcttgga tactggattg ggacgagatt ccttctctat tatttcccaa
    49681 gggaaggttg aggagatttt taattccaag cctgaggaac gacgagctat ttttgaagaa
    49741 gctgctggag ttttaaaata caagactcgc agaaaagaaa ccgagagtaa actgcagcaa
    49801 actcaggata atctggaccg cttagaggac attatctacg agttggataa tcaaatcaag
    49861 cctcttgaga agcaagctga gaatgcccgt aagtttttag acttggaagg acaacgtaag
    49921 gctatttatt tagacgttct ggttgctcaa atcaaggaaa ataaggctga actagagtcg
    49981 acagaagaag agttgactca ggttcaagaa ctcttgatga gttattacca aaagcgtgaa
    50041 aaattagaag aagaaaatca aactcttaaa aagcaacgcc aagatttaca ggctgaaatg
    50101 gccaaagacc aaggcagttt gatggacttg actagtctga ttagtgattt agaaagaaaa
    50161 ttagccctat cgaaactgga gtccgagcaa gtggccttga atcaacagga ggcacaagcc
    50221 cgtttggctg ctttggagga taagagaaat tcactcagca aagaaaagtc tgataaagaa
    50281 agctctttag ctctgttaga gggaaatcta gtccaaaata atcaaaaact caatcgttta
    50341 gaagctgaat tgctggcttt ttcagatgat cctgatcaga tgattgagct tttgcgtgaa
    50401 cgctttgtgg cgcttttaca agaagaagcg gatgtctcaa accaactgac ccgcatcgag
    50461 aatgagttgg aaaatagtcg tcagctttct caaaaacaag cagatcaact agaaaagctg
    50521 aaagagcaat tggctatagc taaagagaag gctagtcagc aaaaggaaga gcttgaaact
    50581 gccaaggagc aggttcagaa attattggct gactatcaag ctattgccaa ggagcaagag
    50641 gagcaaaaaa cttcctatca agctcaacaa agtcaactct ttgaccgtct ggatagtctt
    50701 aaaaacaagc aggctagagc tcaaagtttg gaaaacatcc ttagaaatca cagtaacttt
    50761 tatgcaggtg taaagagtgt tctccaagaa aaagaccgcc ttggtgggat tattggtgct
    50821 gttagtgagc atttgacctt tgatgtgcat tatcaaactg ccttagagat tgcacttgga
    50881 gccagcagtc agcatatcat cgtagaagat gaagagtcgg caaccaaagc tattgatttc
    50941 cttaaacgaa acagagccgg tcgtgcaacc ttccttccgt tgacaacaat caaggctcgt
    51001 acgatttcta gccagaatca agatgttatc gctgtaagcc caggtttcct tgggatggca
    51061 gatgagttgg tgacttttga tactagactg gaagccattt tcaagaattt gctagctacg
    51121 acggctattt ttgatactgt agagcatgcg cgtgcagcag ctcgccaagt tcgttatcag
    51181 gttcgtatgg tgacattgga tgggacagaa ttacgcacgg gtggttccta tgcgggtggt
    51241 gccaatcgcc aaaataacag tattttcatc aagccagaac tggagcaatt acaaaaagaa
    51301 attgctgcag atgaagcaag cttgggttca gaagaagcgg ctttgaagac cttgcaagac
    51361 cagatggcta cattgacaga aagattagaa gccatcaaat ctcaaggaga acaggcacgt
    51421 attcaggagc aaggcttgtc cctcgcttat cagcaaacta gtcagcaagt tgaagaactg
    51481 gaaactcttt ggaaactcca agaagaggaa aaagatcgtc tttctgatgg agattggcaa
    51541 gcagacaagg aaaactgcca agagcgtctt gctgcaatcg ccagtgacaa gcaaaatctg
    51601 gaagctgaga ttgaagagat taagtctaat aaaaatgcca tccaagaacg ctatcaaaac
    51661 ttgcaggaag agctagcgca agctcgtttg cttaagacag aactgcaagg gcaaaaacgt
    51721 tatgaagtgg ctgatattga acgcttaggc aaggaattgg acaatcttga ttttgaacaa
    51781 gaggaaatcc agcgccttct tcaagaaaag gttgacaatc ttgagaaggt tgatacagaa
    51841 ttgctcagtc aacaggcgga agaatccaaa actcagaaaa cgaacttcca acaaggtttg
    51901 attcgcaaac agtttgagtt ggatgatata gaaggtcagc tggatgatat tgctagtcat
    51961 ttggatcagg ctcgccagca gaatgaggag tggattcgca agcaaacacg tgctgaagcc
    52021 aagaaagaaa aggtcagcga gcgcttgcgc catctacaaa gtcaattaac agaccagtac
    52081 cagattagct atactgaagc tctagaaaaa gcgcatgaat tggaaaacct caatctggca
    52141 gagcaagaag ttaaggattt agagaaggct attcgctcac tgggtcctgt caatatagaa
    52201 gctattgacc agtacgaaga agttcgcaac cgtctggact ttctaaatag tcagcgagat
    52261 gatattttgt cagcgaaaaa tctgctcctt gaaaccatta cagagatgaa tgatgaggtc
    52321 aaggaacgct ttaaatcaac ctttgaagct attcgtgagt cctttaaagt gaccttcaag
    52381 cagatgtttg gcggaggtca ggcagacttg atattgactg agggcgacct tttaacagct
    52441 ggtgtggaga tttctgttca acctccaggt aagaaaatcc agtcgcttaa cctcatgagt
    52501 ggtggtgaaa aagctctatc ggctcttgcc ttgcttttct ccattattcg tgtcaagact
    52561 attccatttg ttatcttgga tgaggtggaa gctgcgctgg atgaagctaa tgttaaacgt
    52621 tttggggatt acctcaaccg ctttgacaag gacagccagt tcatcgtcgt aacccaccgt
    52681 aagggaacca tggcagcggc tgattctatc tatggagtga ccatgcaaga atcaggtgtc
    52741 tcaaaaattg tttcagttaa gttaaaagat ttagaaagta ttgaaggatg acaattaaac
    52801 tagtagcaac agatatggat ggaaccttcc tagatgagaa tgggcgcttt gatatggatc
    52861 gcctcaagtc tctcttggct tcctataagg aaaaagggat ttactttgcg gtggcttcgg
    52921 gtcggggatt tctgtctctg gaaaaattat ttgctgatgt tcgtgatgac attattttca
    52981 tcgcggaaaa tggcagtttg gtagagtatc aaggtcagga cttgtatgaa gcgactatgt
    53041 ctcgtgactt ttatctggca acttttgaaa agctgaaaac gtcaccttat gtagatatca
    53101 ataaactgct cttgacgggt aagaaggggt catatgttct agatacggtt gatgagacct
    53161 atttgaaagt gagtcagcat tataatgaaa atatccaaaa agtagcgagt ttggaagata
    53221 tcacagatga cattttcaaa tttacaacca acttcacaga agaaacgtta gaagctggtg
    53281 aagcttgggt caatgataat gtccctggtg tcaaggctat gacaactggc tttgaatcta
    53341 ttgatattgt tctggactat gtcgataagg gtgtagctat tgttgaatta gctaaaaaac
    53401 ttggtatcac aatggatcag gtcatggctt ttggagacaa tcttaatgac ttacatatga
    53461 tgcaggttgt gggacatcct gtagctcctg aaaatgcacg acctgaaatt ttagaattag
    53521 caaagactgt gattggtcac cataaggaac ggtcggttat agcttatatg gagggcttat
    53581 aatggcagat ataaaattga ttgcattgga cttggacggg accttgctga ctactgataa
    53641 aaggctgacg gatcgtacca agtcaacctt gaaagctgcg cgtgatcgtg gtatcaaggt
    53701 cgtattgaca actggtcgtc ccttaaaagc catggacttc tttctccatg agttagggac
    53761 tgacggccat gaagatgagt ataccattac ttttaatggt ggtttggttc agaaaaatac
    53821 aggtgaaatc cttgataaaa cagtcttttc atatgctgat gtggcacgct tgtatgagga
    53881 aacagagaaa ttatcactgc ctcttgatgc catctcagaa ggaacagttt atcaaatcca
    53941 atcggaccaa gaaagtcttt atgccaaatt caatccagct ttgacttttg ttccagttga
    54001 ctttgaagac ctgtctagtc aaatgaccta caacaaatgc gtgactgcct ttgctcaaga
    54061 acccttggat gcagccattc agaagatttc tccagaattg tttgaccaat atgaaatctt
    54121 taaatcacgt gaaatgttgc tagaatggtc accaaagaat gttcataaag caacaggttt
    54181 ggcaaaacta atcagccatc ttggaatcga ccaaagccaa gtgatggctt gtggtgacga
    54241 ggccaatgac ctctctatga ttgaatgggc aggtcttggt gttgctatgc aaaacgctgt
    54301 tcctgaagta aaggcagccg caaatgtagt gacgccgatg accaacgatg aggaagctgt
    54361 cgcctgggct atcgaagaat atgtgttaaa ggagaactaa gatatgggat tatttgaccg
    54421 tctattcgga aaaaaagaag aacctaaaat cgaagaagtt gtaaaagaag ctctggaaaa
    54481 tcttgatttg tctgaagatg ttgatcctac cttcacagaa gttgaggaag tttctcagga
    54541 agaagcagag atggaaattg ttgaacaagc tgtgttccaa gaagaggaaa tccaagacac
    54601 agttgaagaa agtctggatt tagagccagt tgtagaagtt tctcaaaaag aagtagaaga
    54661 atttccaaac tcacaagaag tcacagagga agagaagctt gagcacgaag gaactgtaga
    54721 agaaaataat tctgaagtgc ttgaaccaga agctcctcaa acagaagaaa ctgttcagga
    54781 aaaatatgac cgcagtctta agaaaactcg cacaggtttc ggtgcccgct tgaatgcctt
    54841 ctttgctaac ttccgctctg ttgacgaaga atttttcgag gaactggaag aactgctgat
    54901 tatgagtgat gttggtgtcc aagtcgcttc taacttaacg gaggaactac gttacgaagc
    54961 caagcttgaa aatgccaaga aacctgatgt acttcgtcgt gtcatcattg agaaattggt
    55021 tgagctttat gaaaaggatg gtagctacga tgaaagcatc cacttccaag ataacttgac
    55081 agttatgctc tttgttggtg tgaatggtgt tgggaaaaca acttctatcg gaaaactagc
    55141 ccaccgctac aaacgagctg gtaagaaggt catgctggtt gcagcagata ccttccgtgc
    55201 gggtgcagta gctcagctag ctgaatgggg ccgacgagta gatgttccag tagtaactgg
    55261 acctgaaaaa gctgatccag ccagcgtggt ctttgatggt atggaacgtg ccgtggctga
    55321 aggtatcgat attctcatga ttgatactgc tggtcgtctg caaaataagg ataaccttat
    55381 ggctgagttg gaaaagattg gtcgtattat caaacgtgtt gtgccagaag caccacatga
    55441 aaccttcttg gcacttgatg catcaacagg tcaaaatgcc ctagtacagg ccaaagaatt
    55501 ttcgaaaatc acacctttaa ccggaattgt tttgactaag attgatggaa ctgctcgagg
    55561 aggtgtggtt ctagccattc gtgaagaact caatattcct gtaaaattga ttggttttgg
    55621 tgaaaaaatc gatgatattg gagagtttaa ctcagaaaac tttatgaaag gtctcttgga
    55681 aggtttaatc taatcagaag caaaaatcct gcaaggcata aacttgcagg aaattttttt
    55741 attctaagcg accatcttga cgataggcga tatctggttg ccaagtccat ttggcaccga
    55801 atttttcaag taggtcaaag ctggcttgag gtcccatgct tccagcttta tagtcatgaa
    55861 gtggggcacc attttcagcc cagagctttt caatacgatc aatcaacttc catgacgcac
    55921 caacttcatc ccagtggcta aagttagttg agttgttatt taggacatca taaatcaatt
    55981 tttcgtatgg ttctggagaa gcaccagttg cagtcgcgtc tgtacgataa tcaagtgagt
    56041 taggagccaa gttaaattct tctcctactt gcttcccatt taggctaaga gagaagcctt
    56101 ctgttggttg aatatagatg gtcaaaatat ttggagcaag tggttctcca aagatagaat
    56161 ccatttgttt aaagacgatg ttgacatgag ttcctttttc agtcagtcgt ttacctgtac
    56221 ggaaaaagaa aggaacacca cggaatcgat cgctgtctac aaagaaggca ccagatgtaa
    56281 aggtttcagt tgttgattct ggattcacat ttggctcgct acgataagag atgtatttta
    56341 tgccatcaat cttaccagag cggtattgcc cacggataaa gtgttctttg agttcttcat
    56401 cagttggatg atagaggttt ttaaagacct taatcttttc agcacgaatc tcgtcttttg
    56461 tgaagcttgc tggtttgtcc atggcgagaa gcgaaagaag ttgtagagtg tggttttgga
    56521 ccatgtcacg gagggcaccg gattggtcat agtagccacc acgttcttct acacccaagc
    56581 gctccgcaaa ggtaatttga acattgtcga taaaatcctt gttccaaacg ttttcaaaaa
    56641 tcaagtttgc aaagcgaact gcaaagatgc tttggatcat ttccttacca agataatggt
    56701 cgatacggaa aatttgttct tcgtcaaatg ttgctaggag ttcgtcattc aacttgcttg
    56761 cagttgcgta atctgtacca aatggttttt caacgatcaa gcgctcaaaa cctttgccat
    56821 cgacaatgtt ttcagatttg aggtgtttgg caatggttcc aaagaactga ggtgccatag
    56881 acaagaagaa gagcttattg tgttcagctt ggtatttttc attaagctca gcttgtaatt
    56941 gacgcaaagc aatataatgt tccgaatcat tgacatcatg gctttgatag tagaagtggc
    57001 tagcaaattc ttgggcttgc tcggtactat ctgccaaatc aaggatggac tcgacaacta
    57061 cagattcaaa atattcctta ctccaaggtc tacgggcagt tccaataacg gcaaagtgct
    57121 tggaaagatt gccggattta tatagtctaa aaagggaagg gtagagcttg cgtttagcca
    57181 ggtctccact cgcaccgaaa attgtaacaa taaccttaga tgacatctag ctacctaatt
    57241 tctattttta ttcctagtct tgctaggtat gaggaaacct catttcataa acttaattct
    57301 aacataattt tccgaaaaat caaaaattcc aatacgaggt agaaaaactg caaggaaatc
    57361 cttacagttt gagtttagac gtttaagacc ttatctaaga actctttcag acgagggtgt
    57421 tgtgggttat caaagatttg gtcaggtgtt ccgtcttcaa ggaactcgcc atctgcagta
    57481 aagataacgc ggttggcaac ctgacgagca aatcccatct catgggttac gataatcatg
    57541 gtcatgcctt gctcagccaa ttccttcata acgttaagta cgtctccaac catctcaggg
    57601 tcaagggcag aagttggttc atcgaagagc atgatgtctg gattcattgc taggccacga
    57661 gctatggcca cacgttgttt ttgaccacct gataggctat ctggattggc attagcttta
    57721 tctgctagtc caaccttttc aagcaactcc attcccaatt tctcagcttc ttccttagtc
    57781 atcaacttgt gctcaatagg agcaaaggtg atgttgtcca atacagacat atgagggaag
    57841 aggttgaagt gttggaatac catgccgata ttttcacgga cgtggtcaac attggttgtt
    57901 ttttcagtta aatcatagcc gttcacagtg atgtgaccgc tagtgacttc ttctaaaaga
    57961 ttgaggctac ggaggaaagt tgacttacca gaacctgaag gaccgatgat acaaacaaca
    58021 tctccttcat agaacttagt cgtaattcct tttaggactt cattttttcc atagtgcttg
    58081 tgtaaatcat ttacatcaat ttttaatttt gccattaacg aatcctcttt tctaagcgtt
    58141 tcgctagtct agtcaaaagt gtgataatta caagatagaa gatagcaagg attgcataca
    58201 tcttgaaact ttggtagtta cgagcaatga taatcttacc agtttggaag agttcaacca
    58261 aaccgatagc agatacgata gttgtatctt taagagcgat aacgaattgg ttgacaaagt
    58321 ttggcaacat caatttagtt gcttgtggca agataatctt acgcatggtt tttccataag
    58381 agatacccaa gcttcggctg gcttccattt ggccaactgg aacggcctga ataccaccac
    58441 gaacgatttc agcgatataa gcagccgcat tgagtgagag ggcaattgtt ccagctacaa
    58501 agtcgttaat tgggctttgt tggcctgtga tagactcgat gaagtttgga attccccaga
    58561 agatgaaggc tgcaagaatc atcaatggaa taccacgaat aacgtcaacg aaaatctcag
    58621 agatgacgcg aagagatttg tatgggctaa cgctaaacat accgaagata attccgatga
    58681 caatggcaat agcaaatgag ataagagcta gagcaagagt gataccaaga ccgctaagga
    58741 gttgtttgta gttgttttga agcaagcccc agagcgttgt ttcgtcaaca gtacttgttg
    58801 aagcagttga agattcgcta gctaggtatt tgtcaagaat cttttggaat tcaccgtttg
    58861 ctttaaggtt tgcaagtccg ttgttgaaca tttcaatcag ttctggattt gctccttttt
    58921 taacggcaaa ggctgtttca ccgattggag ttccagagat tggagttttc aatttttgac
    58981 cttggctgat agaatatttg agaacaggtt catcatccat aacggcatca atggcaccag
    59041 tgtttaaact gtcatacatt gaagaaccat cagcaaaggt tttgattttg tagccgtatt
    59101 tgctttgatt ttctgttagg aaggtttgag aagcagttcc gtttttaaca ccgactgtct
    59161 ttccttttag atcttcataa gaagcaatat tacttgattc tttgacacca agaatggtat
    59221 tagcagtgta gtatgattct gagaagtcaa aagttgcctt acgagcatct gtgacagaca
    59281 taccagcgat gataccatcg gcttgaccag cttggacagc actgatagca gcatcaaaac
    59341 cagggttggt gatttcaatt tcaaaacctt ggtctttagc gattgcctta atcaattcca
    59401 tatcaatacc agtgtattgg ttgcttgaat tttggaaaac aaaaggggca aaagaagaat
    59461 cgctggcaat gatatattta gccttaacag gaatagcttt taatcctgcg agagtagttg
    59521 tagttggcac tgctgaagat gatgaagcag tccatttctt gataatttta tcaagactac
    59581 catctttttt catttcagac aaggcttggt taaattcagt aaccaggtgc tcgtatttac
    59641 ttcctttttt cacaccgaaa gcaaaacttc ctacagcttc accatccatt tcaatatgga
    59701 ggtcttgacc ttggttaatg gcatattcga taacaggttt gtcatccatc atggcatcga
    59761 tggcaccagc actcaagctg ttgttcatta aatcaccagt gtcaaatgtt ttaatagtaa
    59821 agccatattt atctttgatt gtttcaagga aacgttgagc ggcagttccg tttttaacac
    59881 caacggtttt gccagttaat tggtcgtact tgctaatttt gtgtgacttt gtagtagcaa
    59941 tgacaacttt tgtatcatag taagtatcag acatggtgaa gactttttca cgttctttag
    60001 tctttgtcat ccctgccatg atagcgtcgg cttgcccagc ttgaaccgca ttgactgctg
    60061 cgtcaaatcc aggataggac atctgaatgt tccagccttt aatctcagcg actttgttaa
    60121 taatgtcaac atcaattcct ttataagttt gatctgaatc tttaaactca aaaggtgcat
    60181 aggcggtatc agaaacaatc ttaatcgttt ctgctttggc aatacctaat gagaaaattg
    60241 ggaataaaat tagcaaaaat gctagaaatt ttttcttcat ttttagtctc cttttccgaa
    60301 tattctctca ttatatcaga aaaagtaaaa aaaggcaaat ttttatattt ttcgtgtcag
    60361 aaaatataac attgattttt ccttttcttt cttgaattgc tattaaaaag tgctataata
    60421 atagtatata tagaagaaaa gaggacgggg atatgaagaa caaaagaata tttaaagact
    60481 tccaagcttc aaaaatgagt ttaaacattt acacaagccc cttgttagcc tttgtttttg
    60541 tcttcatagg agagtttgtg gcttttactt tgtatggtat tggcttgtta gctctcatcg
    60601 gacttgctag aaattttgga gaggctggtc aaaatcttgc aacctacttg cagaccttgc
    60661 atcagagctt gacggataaa acaagtgact ttcgtttaat tttaggatta ctggcctttg
    60721 gttttattct taacactgtg ttcagatgga caagaaaagt tgagaaaaga cctattcgaa
    60781 ccttgggatt ttatagagag aatttcctca gcaatcttct gaaaggattt agtctaggct
    60841 tggcactttt tcttctgacc ttgttaggtt tagtggtctt aggtcaatat cgtttggaat
    60901 ccattcactt gaatccttat tctcttgcct ttgtcgtctt tactatccca ttttggattt
    60961 tacaggggac agcagaagaa gtggtggccc gtgcttggct acttcctcaa ttggcctcaa
    61021 gaaccaatct aaaactagct attcttatat ctagcctgtt ctttaccctg cttcatatgg
    61081 gcaattctgg cctcacccct ctatctctag taaatctctt tttattcgga gttgccatgg
    61141 ctctttatct tctcaaaact gatacagttt ggggtgttgc aggtattcat ggtgcttgga
    61201 attttgctca gggtaatctc tttgggattt tagttagtgg tcaaccgtca ggaacgtctc
    61261 tgatgacctt tttaccacaa ggcaatcaag attggctatc aggtggttct tttggcatag
    61321 aaggttccat tatgacaagt ctggtattac tactgctgat tgtctatctt gctaataaat
    61381 taaagaaaga aaatgaaagg atgtgacttc ggtccgtcct tttcttcgtg aaaatactat
    61441 aagtatgcta aaataggaat agcacatgga gagaggattc ttatgatcaa tcacattaca
    61501 gataatcaat ttaaactagt atcaaaatat caaccatcag gagatcaacc ccaagctatc
    61561 gagcagttgg tggataacat tgagggggga gaaaaagctc agattctgat gggggcgact
    61621 ggaacaggga agacctatac tatgagtcag gtcatttcta aagtcaataa accaactctg
    61681 gttattgccc acaataaaac tctggctggt cagctctatg gggagtttaa ggaatttttc
    61741 cctgaaaatg cagttgagta tttcgtatcc tactatgatt attaccagcc agaggcctat
    61801 gtcccttcta gcgataccta tattgagaag gatagttctg tcaatgacga gattgacaag
    61861 cttcgccact cagctacctc agcccttttg gagcgtaatg atgttattgt cgtggcctca
    61921 gtctcttgta tctatggttt gggttcgccc aaggaatacg ctgatagtgt cgttagtctc
    61981 cgtcctggtc tagagatttc tcgtgataaa ctcttgaatg acttggtcga tattcagttt
    62041 gaacgtaatg atattgattt ccaacgcgga agatttcgcg ttcgtgggga tgtggtagag
    62101 attttcccag cttcccgaga tgaacatgcc tttcgagtag aattttttgg agacgaaatt
    62161 gaccgtatcc gtgaggttga ggctctgaca ggtcaggtat tgggagaggt ggatcatttg
    62221 gcgattttcc cagctactca ctttgtgacc aatgacgacc atatggaagt tgccgttgcc
    62281 aagattcaag cagaattaga agagcagtta gctgtctttg aaaaggaagg taaactgctt
    62341 gaagcccagc gtttgaaaca gcggacagag tatgatatcg aaatgttgcg tgagatgggc
    62401 tataccaatg gggttgaaaa ttattctcgc cacatggatg gacggagcga aggagagcct
    62461 ccttatacgc ttctcgactt cttcccagat gatttcttga ttatgattga cgagagtcat
    62521 atgaccatag ggcaaatcaa gggcatgtac aatggagacc gttcgcgtaa ggaaatgcta
    62581 gtaaattatg gtttccgttt accgtctgcc ttggacaatc gtcctctccg tcgtgaggag
    62641 tttgaaagcc atgtgcatca gattgtttac gtatcagcga cacctggtga ctatgaaaat
    62701 gaacagactg agacggtgat tgagcaaatc attcgaccga cagggctttt ggatcctgag
    62761 gtggaagtcc gtccgactat gggacagatt gatgatctct taggtgaaat caatgcccgt
    62821 gttgaaaaga atgaacgaac ctttatcacc accttgacca agaaaatggc agaggacttg
    62881 accgactatt tcaaggaaat gggcatcaag gtcaagtaca tgcactcgga tatcaagacc
    62941 ttggaacgga cggagattat ccgtgatctc cgcttgggtg tctttgatgt cttggttgga
    63001 atcaatctcc ttcgtgaagg gattgacgtt cctgaggtta gcttggttgc cattctcgat
    63061 gctgacaagg aaggtttcct tcgtaacgag cgtggactca tccagaccat tgggcgtgcc
    63121 gcccgtaaca gtgaaggtca tgtcatcatg tatgcagata cggttaccca gtctatgcaa
    63181 cgtgctatcg atgaaactgc ccgccgtcgg aaaattcaga tggcctataa tgaagagcat
    63241 ggtatcgtac cacagacaat caagaaagaa atccgtgacc tgattgccgt gaccaaggca
    63301 gttgctaagg aagaggacaa ggaagtcgac atcaatagcc tcaacaaaca agagcgcaaa
    63361 gaactcgtca agaaactaga aaaacaaatg caagaagccg tcgaagtgct tgactttgaa
    63421 ctggcggctc agatccgtga tatgatgttg gaagtcaagg ccttggatta ggggaatagt
    63481 atgatttatt taagaaagtt aaagaaagaa gatttgatgt ctttatggga aatggcttat
    63541 tcacagctta atccagtttg gaaacagtat gatgctccct attatgatga ttatcagtat
    63601 ttttcaaatt ttaaagaatt cgaactacaa aaatcagaat ccattttaag caactcaaat
    63661 cgccttggta tttttgttga tgataaacta gttgggactg tttcgcgtta ttgggtatgt
    63721 aaagaaacaa gatggatgga attgggaatt ggtatttatg ataaaaaatt ctggaacact
    63781 ggtattggga aagttgctat gttgcagtgg atagatagga cgtttcagga ttacttggag
    63841 ttggagcatc tgggtttgac aacttggtca gggaatcttg gtatgatgaa acttgctgaa
    63901 aaattaagaa tgaaaaaaga agctcatatt ccaaaagttc gttattatca aggtaaatat
    63961 tttgatagta ttaaatatgg tattttgaga gaagactggg agaaaataaa tgacggttat
    64021 tatcaaatca atggaaactc ctgaagagat agaaggtaaa tccctcgttc actggcaaac
    64081 gtggagagag gcttatgatg accttttgcc tgcagaattt caggagacaa tgacattaga
    64141 aagatgtcga ttctttagtc aaaagtatcc agaaaataca ttgattgcga taggtgatct
    64201 gaaggtagtt ggttttatca gttatggtaa ctttcgtgat gatactattc aagctggtgg
    64261 aattattgct ttatatgttt taaaagacta ttacggaaaa ggcatagcac aaaagttaat
    64321 gaaagcagct ttgactgctc ttaatcattt ttctgaaatt ttcttatggg tattgaaaga
    64381 taacaagcgc gccattgctt tctatcaaaa aatgggtttt acttttgatg gacaagaaaa
    64441 aatacttgaa cttggaaagc ctataaagga aaaacgaatg gtgttctatt ctaaataatt
    64501 ttaaaaaagt aaaagataat atctctggta gtaagtctga aaatttaata aattagaaag
    64561 cgagtaaatt tatgtcccgt tcccaattaa caattttaac aaatatctgt ctgattgaag
    64621 acctcgaaac gcagcgcgtg gtgatgcagt atcgcgcccc tgaaaacaat cgctggtctg
    64681 gttatgcctt tcctggaggt catgtagaaa atgatgaggc ttttgcggag tctgtcattc
    64741 gtgaaatcta cgaagaaaca gggttgacta tccaaaatcc tcaacttgtc ggcattaaaa
    64801 attggccact agatacaggt gggcgctata ttgtcatttg ttataaggcg actgagttct
    64861 ctggtaccct tcaatcttca gaagagggag aagtttcttg ggtgcaaaaa gaccagattc
    64921 caaacttaaa tctggcctat gatatgctac cattgatgga aatgatggaa gctcccgaca
    64981 agtcagagtt tttctaccct cgccgtacag aagacgattg ggaaaagaaa atcttctagt
    65041 cttttactaa ataacctagc tgatccaagg cctcctcgat atagtggagg tcttgttgtg
    65101 tttcggcttc gactaggtgg taatggatgc catctgtcaa ttcagataga ggtctaaagt
    65161 cagaatgctc gacttgttct agaaaatgtt gcacatctct gcgacaagac agtttaagca
    65221 aggtttcaat ttctccataa acgggatggt caatcaaggt attctggaca tgcccaccat
    65281 tatcgacaat agcaaggagt tcctgaccga tttcttcaac ttcatgtttc actttgaaaa
    65341 gtttgtgaac ataaggattg gtatcaattt gcttatagat gtagccacga ttggtggata
    65401 ggataggagc gccatcggct ctcaaaattg caatgtcctg cacaatgacc tgacgtgtga
    65461 catgaaaatg ttccgccaaa ctttggccat taagggcttt aggagcttct ttcaagagtt
    65521 ggagcagggc ttgtttgcga tcttttgtca tagcttttcc ttttaacggc gttttcgaag
    65581 cactttatag acagctagtg ctaatgtata gtctaccata ctatggataa ttgtgccaaa
    65641 tccaactagt acaaatagaa catagaacat gttttctaca ttggtacccg aagttgcgta
    65701 aaaaaggaca caggctaata cttcagcaag ggcatgaaca acagccaaaa caaaattgaa
    65761 aacccaggaa gattttggtt tatctagggt atcggggaat ttttgtaggt aaagagctcc
    65821 taaagcacca aaagatatat gggaaaaagc ccgaaaaacg ataaccatgg gatagccagc
    65881 catcaaaaat ccaaaactag aggctaggat gacaaaaact gccatcaagg gcgacaagaa
    65941 catggctata aaaatagcga tgtggctccc caaagtatag gaagcaggtg gaatgacaat
    66001 cttgaaaggc ataacaattg gaatcaaaat cgcaatagcc gttaaaaggg ctgtcattgt
    66061 cataaattgt gtctttttcc gtgtattcac aagaatctcc tttttaactg catatacact
    66121 agtatggtac aataaaccag acaataaagc aagaatttac ttgggtttat agatcatttt
    66181 ttagttaaaa gttatagtag attgaaact
//
LOCUS       DAVBNN010000004        64449 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBNN010000004 DAVBNN010000000
VERSION     DAVBNN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.004"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VQ847_000209"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VQ847_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3049619.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VQ847_000210"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VQ847_000210"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3049620.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VQ847_000211"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VQ847_000211"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3049621.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VQ847_000212"
     CDS             complement(3790..5058)
                     /locus_tag="VQ847_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3049622.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VQ847_000213"
     CDS             complement(5178..5546)
                     /locus_tag="VQ847_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3049623.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VQ847_000214"
     CDS             complement(5539..5805)
                     /locus_tag="VQ847_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3049624.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VQ847_000215"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VQ847_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3049625.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9373..9942)
                     /locus_tag="VQ847_000216"
     CDS             complement(9373..9942)
                     /locus_tag="VQ847_000216"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3049626.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VQ847_000217"
     CDS             complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VQ847_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3049627.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11212..11406)
                     /locus_tag="VQ847_000218"
     CDS             complement(11212..11406)
                     /locus_tag="VQ847_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3049628.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="VQ847_000219"
     CDS             complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="VQ847_000219"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3049629.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="VQ847_000220"
     CDS             complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="VQ847_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3049630.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14340..15098)
                     /locus_tag="VQ847_000221"
     CDS             complement(14340..15098)
                     /locus_tag="VQ847_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3049631.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15156..16337)
                     /locus_tag="VQ847_000222"
     CDS             complement(15156..16337)
                     /locus_tag="VQ847_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3049632.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16520..16999
                     /gene="rlmH"
                     /locus_tag="VQ847_000223"
     CDS             16520..16999
                     /gene="rlmH"
                     /locus_tag="VQ847_000223"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3049633.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17043..17116
                     /locus_tag="VQ847_000224"
     tRNA            17043..17116
                     /locus_tag="VQ847_000224"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17077..17079,aa:Arg,seq:tct)
     gene            17281..17406
                     /gene="comC"
                     /locus_tag="VQ847_000225"
     CDS             17281..17406
                     /gene="comC"
                     /locus_tag="VQ847_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3049634.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17427..18752
                     /locus_tag="VQ847_000226"
     CDS             17427..18752
                     /locus_tag="VQ847_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3049635.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18749..19501
                     /locus_tag="VQ847_000227"
     CDS             18749..19501
                     /locus_tag="VQ847_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3049636.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19553..19624
                     /locus_tag="VQ847_000228"
     tRNA            19553..19624
                     /locus_tag="VQ847_000228"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19586..19588,aa:Glu,seq:ttc)
     gene            19630..19703
                     /locus_tag="VQ847_000229"
     tRNA            19630..19703
                     /locus_tag="VQ847_000229"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19664..19666,aa:Asn,seq:gtt)
     gene            complement(19744..20286)
                     /locus_tag="VQ847_000230"
     CDS             complement(19744..20286)
                     /locus_tag="VQ847_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3049637.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20465..21232
                     /locus_tag="VQ847_000231"
     CDS             20465..21232
                     /locus_tag="VQ847_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3049638.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21236..21655
                     /locus_tag="VQ847_000232"
                     /pseudo
     CDS             21236..21655
                     /locus_tag="VQ847_000232"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21683..21997
                     /locus_tag="VQ847_000233"
     CDS             21683..21997
                     /locus_tag="VQ847_000233"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3049639.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22098..24650)
                     /locus_tag="VQ847_000234"
     CDS             complement(22098..24650)
                     /locus_tag="VQ847_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3049640.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24712..26334)
                     /locus_tag="VQ847_000235"
     CDS             complement(24712..26334)
                     /locus_tag="VQ847_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3049641.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26540..27565
                     /gene="trpS"
                     /locus_tag="VQ847_000236"
     CDS             26540..27565
                     /gene="trpS"
                     /locus_tag="VQ847_000236"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3049642.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27717..29195
                     /gene="guaB"
                     /locus_tag="VQ847_000237"
     CDS             27717..29195
                     /gene="guaB"
                     /locus_tag="VQ847_000237"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3049643.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29246..30343)
                     /gene="recF"
                     /locus_tag="VQ847_000238"
     CDS             complement(29246..30343)
                     /gene="recF"
                     /locus_tag="VQ847_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3049644.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30346..30714)
                     /gene="yaaA"
                     /locus_tag="VQ847_000239"
     CDS             complement(30346..30714)
                     /gene="yaaA"
                     /locus_tag="VQ847_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3049645.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30873..32123
                     /locus_tag="VQ847_000240"
     CDS             30873..32123
                     /locus_tag="VQ847_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3049646.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32120..33403
                     /locus_tag="VQ847_000241"
     CDS             32120..33403
                     /locus_tag="VQ847_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3049647.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33445..34266
                     /locus_tag="VQ847_000242"
     CDS             33445..34266
                     /locus_tag="VQ847_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3049648.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34277..34822
                     /gene="pgsA"
                     /locus_tag="VQ847_000243"
     CDS             34277..34822
                     /gene="pgsA"
                     /locus_tag="VQ847_000243"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3049649.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34819..35646
                     /locus_tag="VQ847_000244"
     CDS             34819..35646
                     /locus_tag="VQ847_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3049650.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35631..36470
                     /locus_tag="VQ847_000245"
     CDS             35631..36470
                     /locus_tag="VQ847_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3049651.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36463..37257
                     /locus_tag="VQ847_000246"
     CDS             36463..37257
                     /locus_tag="VQ847_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3049652.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37316..38134
                     /gene="mreC"
                     /locus_tag="VQ847_000247"
     CDS             37316..38134
                     /gene="mreC"
                     /locus_tag="VQ847_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3049653.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38134..38628
                     /gene="mreD"
                     /locus_tag="VQ847_000248"
     CDS             38134..38628
                     /gene="mreD"
                     /locus_tag="VQ847_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3049654.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38722..39900
                     /locus_tag="VQ847_000249"
     CDS             38722..39900
                     /locus_tag="VQ847_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3049655.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40124..40903
                     /gene="rpsB"
                     /locus_tag="VQ847_000250"
     CDS             40124..40903
                     /gene="rpsB"
                     /locus_tag="VQ847_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3049656.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40982..42022
                     /locus_tag="VQ847_000251"
     CDS             40982..42022
                     /locus_tag="VQ847_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3049657.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42268..42555
                     /gene="tnpB"
                     /locus_tag="VQ847_000252"
     CDS             42268..42555
                     /gene="tnpB"
                     /locus_tag="VQ847_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3049658.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42746..43014)
                     /locus_tag="VQ847_000253"
                     /pseudo
     CDS             complement(42746..43014)
                     /locus_tag="VQ847_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43011..43409
                     /locus_tag="VQ847_000254"
     CDS             43011..43409
                     /locus_tag="VQ847_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3049659.1"
                     /translation="MDAPIPKAPLAHSFGSASIIAHIIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43606..44526)
                     /gene="cysK"
                     /locus_tag="VQ847_000255"
     CDS             complement(43606..44526)
                     /gene="cysK"
                     /locus_tag="VQ847_000255"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3049660.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44811..45446)
                     /locus_tag="VQ847_000256"
     CDS             complement(44811..45446)
                     /locus_tag="VQ847_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3049661.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45502..46800
                     /locus_tag="VQ847_000257"
     CDS             45502..46800
                     /locus_tag="VQ847_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3049662.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46797..47459
                     /locus_tag="VQ847_000258"
     CDS             46797..47459
                     /locus_tag="VQ847_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3049663.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47539..48087
                     /gene="raiA"
                     /locus_tag="VQ847_000259"
     CDS             47539..48087
                     /gene="raiA"
                     /locus_tag="VQ847_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3049664.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48223..50196
                     /locus_tag="VQ847_000260"
     CDS             48223..50196
                     /locus_tag="VQ847_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3049665.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50193..50645
                     /gene="rplI"
                     /locus_tag="VQ847_000261"
     CDS             50193..50645
                     /gene="rplI"
                     /locus_tag="VQ847_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3049666.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50689..52041
                     /gene="dnaB"
                     /locus_tag="VQ847_000262"
     CDS             50689..52041
                     /gene="dnaB"
                     /locus_tag="VQ847_000262"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3049667.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52043..52309
                     /locus_tag="VQ847_000263"
     CDS             52043..52309
                     /locus_tag="VQ847_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049668.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52398..53744
                     /gene="cbpD"
                     /locus_tag="VQ847_000264"
     CDS             52398..53744
                     /gene="cbpD"
                     /locus_tag="VQ847_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3049669.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     regulatory      53827..53929
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54000..54290
                     /locus_tag="VQ847_000265"
     CDS             54000..54290
                     /locus_tag="VQ847_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3049670.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54253..55011
                     /locus_tag="VQ847_000266"
     CDS             54253..55011
                     /locus_tag="VQ847_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3049671.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            55049..56056
                     /locus_tag="VQ847_000267"
     CDS             55049..56056
                     /locus_tag="VQ847_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3049672.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56056..56784
                     /locus_tag="VQ847_000268"
     CDS             56056..56784
                     /locus_tag="VQ847_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049673.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            56903..57361
                     /locus_tag="VQ847_000269"
     CDS             56903..57361
                     /locus_tag="VQ847_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3049674.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57363..59795
                     /locus_tag="VQ847_000270"
     CDS             57363..59795
                     /locus_tag="VQ847_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3049675.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60437..61090
                     /gene="rr06"
                     /locus_tag="VQ847_000271"
     CDS             60437..61090
                     /gene="rr06"
                     /locus_tag="VQ847_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3049676.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61087..62418
                     /gene="hk06"
                     /locus_tag="VQ847_000272"
     CDS             61087..62418
                     /gene="hk06"
                     /locus_tag="VQ847_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3049677.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62501..63028
                     /locus_tag="VQ847_000273"
     CDS             62501..63028
                     /locus_tag="VQ847_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3049678.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63107..>64449
                     /locus_tag="VQ847_000274"
     CDS             63107..>64449
                     /locus_tag="VQ847_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3049679.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNG"
BASE COUNT        20211 a        10987 c        12760 g        20491 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgaatttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aaacatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgcgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacga ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagttttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttt cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 ttgctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tcctcttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agagtttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagctag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacatgga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctaacacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagataag agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catgcttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttggcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacaatcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttaaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctctggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtatca actttgttgt aaagataata
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa taacagacaa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaaca ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtctatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttggtcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac gggaatagaa atttgatcac cattttggta
     7801 ttggacactg acataatcac gatgaattcc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattacct tctattaagt ttacagattc tttacagata cttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agagaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaattctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agaatctgca tgactttgct tttgatgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattca ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgag catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagaaataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacgt caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga tataatcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttattttt cctttcaaaa
     9961 gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat ttttagacat
    10021 taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct tcttcacgca
    10081 agcgtccagc ttcttttacg gccttttcag atccgtattt cactagatct tcatatgaca
    10141 tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca gctgcttgag
    10201 gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca gctgtgaagt
    10261 aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca cctgattctg
    10321 tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca gaaatttctt
    10381 cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca aattcacgaa
    10441 tttgtttgac atagtcgata gagtcaggtt ccgaaaccac atcctcatcc acattagcta
    10501 cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt tgttcctcat
    10561 ctgtaaattc aatggtacga gctgatttcc catcttctag gactggttta atcttttgaa
    10621 gaacattgaa ttctgctact gattctttat ctttttgcgt acgtgccatc ttttctacac
    10681 gcgcatatcg tttgttcact gattctaagt cagcaagaat caattccaga ttaatggtat
    10741 caatatctgc aagcggatct acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt
    10801 catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata ttggccaaga
    10861 atttattccc tagcccctct ccttttgaag ctccttttac aatccctgca atatctgtaa
    10921 attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt ttttgtagac
    10981 gttcatctgg aacttccacc attccaacat ttggatcaat cgtcgcaaat gggtagtttg
    11041 ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca acgtttggca
    11101 aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat ttcaatccct
    11161 aatattataa cacaaaaagg gataaagtgc taaccctcta actaagggtt ctcagtcaat
    11221 aattttattc atttttcgct caaaatcata tcgccccatc atgacaacat gctcacaatt
    11281 actgcatttt attttgatat ctgctcctac acgtgtaatt tcccaacgat tagccttttt
    11341 accagtcgac ttgattgtac aagcgtgtgg ttttttcatc tcaacaaaat ttccaacttg
    11401 atacatacta ctctcctttt ctttttcgat tatatcataa aagaggcgag ccaggctcaa
    11461 cctctttcac ttaatttgta cgaactggtg taatgagctg catgaagtct tcgtcagtat
    11521 ctgctggcac aagagtaaat ggacgaacag ctgagataaa gctaatggtc accttttcgc
    11581 tatttaaagc tttaagagaa tcaatcaagt aagttgggtt gaaactaatg gtcaaatctt
    11641 caccagtaac ctgatcagta tcgatttctt cgtttacttt accaacttct ggagagtgaa
    11701 catgggcgct aacaacccca tccttaattt caagtttcac agtaccattt tgagtcgcac
    11761 ttgataaaag acgggcacgc tccattgact ggcgtaagtt taccacatta aaagtaatag
    11821 tagtgttaaa gtctgttgga atcaagcgat ctgtatcagg atagtttcct tctaggagac
    11881 gagtatagaa gctaatattt tcgcttctaa agaggatttg gttattggca aagaaaatct
    11941 ctacagtttc gatatcatct gtaaataccg ctgaaaattc gcgtagagaa cggctaggaa
    12001 ttacgacatc aaaatcatca ctattttttt caagagtcaa ttttttctgg cttaggcgat
    12061 gagagtctgt tgcaactgtt tttaactctt tgtgttgact caatacgaag tggacacctg
    12121 ttaaaatcgg acgactctct tgtgtacttg cagcaaaggc tgtttcatta ataattttct
    12181 tgagtaattt tgtttcaagt attaaaggag tgcttgctga aatttcttgg attcgtggat
    12241 attgttcgct atcttttcct tttagggtaa tttctgattt gccactggtt aaaacaattt
    12301 gattttgttc aatttcttta aaatcaagag ttacatcagg taaactagat actacattga
    12361 taaagaaaga agcttcaaga aggatcgaac ctaaagaagt aatcaacaaa ccagcatctt
    12421 catttttttg agaaataaaa ttttcaattg agatttgacc atttgaacca attaaagtaa
    12481 taccttcatt ggtcacgtca atttttactg ttgataaaat aggaatggca tttttagaac
    12541 taatagctct cttagtagta tttaatgctt gtagaaataa atttttatta attgaaaaat
    12601 gaatcatgga ttctccttta tttattttta gtattagaaa gataatagta ataatagagt
    12661 ctgtgaaatc tgtggaaaac agcctttaaa caagtcctat caagtttttt agcttgttta
    12721 aaaaatgtgg ataaaaaaga taaaaaacta aaagttatcc acaaattatt tgattttctt
    12781 tttgattgat tcaatttcta aacgtaaatt atcgtcttga tcaatcaaag attttatttt
    12841 ggcatgggca tgaatgactg tggtatgatc ttttccccca aattccttcc caatttttgg
    12901 aagactatta tctgttagtt ctctagataa atacatggct acttgacggg ccaaaacaat
    12961 attttgaagg cgtctacttc ccttcatttc tttgatacta acaccataaa agttaccaac
    13021 ttcagtttgg attttatcaa ttgggatgac gagcatttgg ctaacatctt gtttgcgggc
    13081 tctaatggct tctgcagcaa tatcaatagt gatatccttg atttttttta ctctggcaat
    13141 taaagtgatg tcgttgatgg ctccctcaag atctcgaaca tttgaatcaa attgcccagc
    13201 taggtattct agagtatcac tttggaaatt gtagcctaaa tgttccgttt tactttgtaa
    13261 aatggcaata cgtgtttcaa agtcaggggg tgtgatagtt tgtgtcaatc cccaactaaa
    13321 acgcgtgaca agcctctcct cgagcccttc tagatgtttt ggactacgat cactcgttag
    13381 gacaatctgt ttttgcttgt catgaagggc gttaaaggta ttgaaaaatt cttcctgagt
    13441 tgcgactttt tttccgctga gtgactggat atcatcgatt aacaaaagat caagactacg
    13501 ataggtcttt ttaaactttt ccatttcccc aagtcttagg tgatcaagaa agtcattaat
    13561 aaagctttcg gcagggatat atttaacacg cgcattagga atatttttta gaatttcatt
    13621 tccaatagcg tttaataagt gagtcttacc aaggcctggt cctccataga taaaaagagg
    13681 gttataggtc agagccaaat cttcagagac agctaaagcg gctgatacag cccaaacatt
    13741 tccatcccct tgaataaagt tatcaaaggt atacttttct tttaatcccg tatctgaata
    13801 aggaatagat actaactttg gactatagtc ataaagagtt aaatttgtag cttcttcaac
    13861 ttgtgagcta gtcgtatctt gaggtttggt gaaaatatag tggggagtta tttcagcgtc
    13921 ataaatttca aaaccagcta ctacaataat atcttttagt tgtttttccc agaccatttc
    13981 catttcagag cgaggtagaa atatagtggc aacattttcc tctaccttga taagttcagc
    14041 ttgaatagca tagaaatcat acatggatcg agtcagtctt tcttgtgcaa attctaatat
    14101 acgattccaa aattgttttt ctttcaatcc tttctcctcc tttactattt aaaagtttaa
    14161 tactagagat attttaccat agatagcaag aattttccac aagctgtgaa aaataatcca
    14221 caatgttacc aaactttatc cacaggttgg ggataaaaga agaaattatt gatttattaa
    14281 gctttttatc gaaaaacata gtggataacc ttgtgagata aaaaaataaa agaacagcct
    14341 tatttcaggc tgttgataat tctactatat tcttcttgat ttgaaaaaga aataatgatt
    14401 tttccactgt cttttttaga tagtttaatt tctacatcta atccgagtag ttttcttaac
    14461 tgtttttctt cattttgtat gaaatgatta gttttttgct gtttcttttg ttttttctct
    14521 gtcagaagag cttctaattt ccttacagaa atatcttctt ctataatccg ttgaaagaaa
    14581 tagtcttgtt gttccttatt taacccaact agggaacgcg catgggcttg tgatagtttg
    14641 ccattttcta cttctgaaag aatctgttct ggcaaggaaa gtaaacgaat ggagttgctg
    14701 atatatggac gagacttgcc catcttatct gcaatttcag catgggtgaa tcctttctct
    14761 acgagagatt cataggcgcg tgcttcttct attgggttta aattttctct ctgtaaattt
    14821 tcaataatgg actggaccat catctcttgg tctgaaatct gtttaacaac agctgggata
    14881 gaccgtagac cagctaaaag tgaagcccga tagcgtctct ctcctgcaag gatttcataa
    14941 ccaataacag gagattgacg aacaataatc ggttgaatga ccccattttc tttgatagac
    15001 tgtgctagtt catctagttt ttctctatca aattcttttc ggggttgata gggatttttt
    15061 tgtatatctg tgatagaaat catttcaaat ttttccatga ttctacacta acacatcttt
    15121 tctcttatgt aaagctttct ttacatagat gtcaattaag attctaaatc acctgaactc
    15181 ttgttaagtt tgatagaggt agtttcttct ttcccgttac gatagtaggt tatcttaatg
    15241 gtgtctccga tagaatggtt gtaaagagca ctttgtaagt ctgttgatga agcaatctct
    15301 ttgtcatcta cttttgtaat tacatcgtat ttttcaaggt gaccattggc aggcatatta
    15361 ctttgtaccg aacgaacaat tacaccagat gtaacattac ttggaatatt gagtcttctg
    15421 atgtcgcttg tactcacatt agataaatta accatctgga ttcccaaagc tggacgcgtc
    15481 acttttccgt ttttttctaa ctgttcaata atattgatag catcatttgc aggaattgcg
    15541 aaaccaagac cttctacaga tgttcctcca tttgtagcaa ttttacttga ggtaattccg
    15601 ataacctgcc cttgaatatt gatcagtggg ccgccagagt tacctgggtt aatagcagta
    15661 tcagtttgga tggcttttgt agaaatagct tgtccatctt ccgattttaa ggatacattt
    15721 ctattgagac tggatacgat accttgagtg acagtatttg catattcaga acctaacggg
    15781 ctaccgatgg caatagcagt ttctcctaca gttaacttac tagaatcacc aaactcagct
    15841 actgttgtca ctttttctga agagattttg acgacagcaa tatcagagaa agtgtcagct
    15901 ccgacaattt ttccaggtac tttagtccca tctgacaatc gaatatctac tttgctggcg
    15961 ccatttataa cgtgattgtt ggtgacgatg taagcttctt tatcattctt tttataaata
    16021 actccagatc cttcactaga gattcgctga gaatctgtgt cagtatcatc attgccaaat
    16081 acgctatttt gtctgtttgc cgaataagta ataacagaaa caacagcatc ttttactttg
    16141 ttaacagcct gtgttgttga attttcgttc ttataggcag tttgtgtaat agtactattg
    16201 ttgttagagt tgtttacact acttttttga gttagttgag ttattgaaaa actacccaag
    16261 gctccactaa aaaagctaat gacgataacg actaataatt gaaaccattt tttgtaaaat
    16321 gtttttagat gtttcatatt tgcctccata tgtttgaatt actgaaagta taaactgact
    16381 agcttaatta taacttaaac acaaaagttt tacacaaact gtggataact cttttgaaat
    16441 tgtgattttc ttaattgaaa tctatttttt attttgtgaa taagatgtga aaaaatagag
    16501 aatatgttag aatagagtca tgaaaattaa agttgtaaca gttgggaaac tgaaagaaaa
    16561 gtatttaaaa gatggtatcg cagagtattc aaaacgaatt tctagatttg ctaagtttga
    16621 aatgattgag ttatcagatg aaaaaacacc agataaggcc agtgaatcag aaaatcaaaa
    16681 gattttagaa atagaaggtc agagaatttt atcaaaaatt gctgaccgtg atttcgttat
    16741 tgtgttagcc attgaaggga aaactttctt ctcagaagaa tttagtaagc agttagaaga
    16801 aacttctata aaaggatttt ctactcttac ttttattatt gggggaagtt taggattgtc
    16861 atcatctgta aaaaatagag ccaatctttc tgtcagtttt ggtcgcctaa ccttacccca
    16921 tcagttaatg agactagttc ttgttgaaca aatctatcgc gcttttacga ttcagcaggg
    16981 attcccctac cataaataga aaattgactt ttaattgaat ttttggtaga ataattgtat
    17041 taggtctcat agctcagctg gatagagcat tcgccttcta agcgaacggt cgcaggttcg
    17101 aatcctgctg ggatcaatat aatagcaaag ctgggaattt tcccggcttt tttcttaaaa
    17161 aagtacactt tgggagaaaa aaatgacagt tgagagaatt ttatctaaaa cgaaattcca
    17221 ttttgtataa tggtttttgt aagttagctt acaagaaaaa acattttagg agattttatt
    17281 atgaaaaaca cagttaaatt ggaacagttt gtagctttga aggaaaaaga cttacaaaag
    17341 attaaaggtg gggagatgag gttgtcaaaa ttcttccgtg attttatttt acaaagaaaa
    17401 aagtaatgaa ataaggggaa agagtaatgg atttatttgg atttgggacg gttattgttc
    17461 attttttaat tattagtcac agttaccatt ttatttgtaa aggtcaaata aatagaaaag
    17521 aattattcgt ttttggtgct tatacattac taacagaaat agtatttgat tttcccttat
    17581 atattctata tttagatggg ttagggattg aaagattttt atttcctttg ggattatatt
    17641 cctattttcg atggatgaaa cagtatgaga gggatagagg actattccta agtttactac
    17701 tatctctttt atatgagagc actcataact ttctgtccgt aactttctcc tctataacag
    17761 gagataattt tgttttacaa tatcatttcc cattcttttt cgttgtgacg gtgttaacct
    17821 attttgttac attaaaaatc atttactatt tccatttgga actagcctat tttgatgagg
    17881 actaccttta tcctttcttg aaaaaagtat tttttgcttt actattgcta catattgtat
    17941 ctttcgtttc agatatggta agtacgatta aacatttgaa tagttttgga agtattttgt
    18001 catctattgt ctttatctct ctccttttga ccttctttgc aatgaattct cataaagttc
    18061 aaatggagaa agagattgct ttgaagcaga agaaatttga acagaaacat ttacagaatt
    18121 acacagatga aattgttggt ctgtataatg aaatccgtgg ttttcgacat gattatgctg
    18181 gaatgcttgt cagcatgcag atggcaattg acagtggtaa tttacaggaa attgacagaa
    18241 tttacaatga agttttagtc aaagcaaatc ataaattgcg ttcagataag tacacttact
    18301 ttgatttgaa caacatagaa gactcagctt tacgaagttt ggttgctcag tcaattgtct
    18361 atgctcgaaa taatggtgta gagtttacac tggaagtaaa agatacgatt accaagcttc
    18421 caattgaact attggatttg gttcgtatca tgagcgtttt attgaataat gctgtcgaag
    18481 gatcggctga tagctataaa aagcagatgg aagtagcagt tattaagatg gaaactgaaa
    18541 cagttattgt gattcagaat tcatgtaaaa tgacgatgac tccttcagga gatctatttg
    18601 ccttaggatt ctccactaag ggaagaaatc gcggagtcgg attaaataat gtgaaagaac
    18661 tactagataa gtacaacaat attattttag aaacagagat ggaaggcagt acatttagac
    18721 aaatcattag atttaagagg gaatttgaat gaaagtttta attttagaag atgttattga
    18781 acatcaagtg agactagaga gaatattgga tgaaatttcg aaagaatcga atattccaat
    18841 atcatacaag acaacgggaa aagtccgtga atttgaagaa tacattgaaa atgatgaagt
    18901 aaatcagctt tatttcctag atatcgatat tcatggaatt gagaaaaagg gatttgaagt
    18961 ggctcagctc attcgtcatt acaatcctta cgctattatc gtctttatca ctagtcgatc
    19021 agagtttgcg actctaacat ataaatacca ggtatcagcc ctagattttg ttgataagga
    19081 tatcaatgat gagatgttta agaagagaat tgagcaaaat atcttctaca cgaagagtat
    19141 gttacttgaa aatgaagatg ttgtagatta tttcgactac aattacaagg gaaatgattt
    19201 aaaaattcct taccatgata ttttgtatat tgaaacaaca ggggtatctc ataaattgcg
    19261 cattattggt aagaattttg caaaagagtt ttatggtacc atgacagata ttcaggaaaa
    19321 ggacaaacat actcagcgat tttattctcc tcacaagtca tttttggtaa atataggcaa
    19381 tatcagagaa attgatcgaa aaaacttaga aattgttttc tatgaagacc atcgttgtcc
    19441 tatttcaaga ttaaaaatta gaaaattaaa agatatttta gagaaaaaat ctcaaaagtg
    19501 attgacaatt agcaagaaat tgatataatg gttatatctg ctacagatag aaggtccgtt
    19561 ggtcaagggg ttaagacacc gccttttcac ggcggtaaca cgggttcgaa tcccgtacgg
    19621 actattttat ccgccatagc tcagttggta gtagcgcatg actgttaatc atgatgtcgt
    19681 aggttcgagt cctactggcg gagtatagat aaaagggaac acagctgtgt tcctcttttt
    19741 gtatcaattt gtatcaccaa gcattttcat aaggaagtct gttatttctt gagaactttc
    19801 tttttttcca tgtgcaatcc aagtttggca gacaccaaaa agtgcatgag ttagatagat
    19861 gctactatat tctaattcgg tggtatttag attcagttgc ataaatcgct tttgtaaatc
    19921 tgtactaagc atgatatgaa gtttatttcg taagaaattt tggatttctt tagtcccatt
    19981 ttcagaaaga agggcagcca gaagtggttc tgactctaga tattcaaaaa cttctaaaat
    20041 agcgtctctt ttgtgatgag catgtttttg aaaaatatat tcaaatgtat ggaatagctt
    20101 gctttgatag tgctcaatca tatcatactt atccttatag tgagtataga agctggaacg
    20161 actaattccg gctttttcta ctaatttgac agtagaaatt ttatcaaatg gctgttccat
    20221 cagtaattgt accatagcat tttcaatagt tcgctttgtt tttaagcgtt tgttactttc
    20281 ttgcatattt cctccttgta aacaaattag actatatgtc taaaaataga ttttttatct
    20341 tgtaatttag attttttaat gtataatcta ttatatcaaa attttagaca atatgtttaa
    20401 aaaaggagaa actaagttta aagaatggaa agcaatttaa aaaaaaccaa cctttattat
    20461 tgtcatgatc gggatttctc ttattccaga tctgtacaat atcatatttt tgtcatcaat
    20521 gtgggatcca tatgggcaat tgtctgactt acctgtggca gttgtaaata atgataaaga
    20581 ggcttcctat aatggtaata ctatggcaat aggaaaagac atggtgtcca atttaaaaga
    20641 aaataaaacc ttggattttc attttgtaga tgaagaggaa ggaaagaagg gattggaaga
    20701 tggcgattac tatatggtag tgactttacc aagtgattta tctgaaaaaa caactacatt
    20761 atccaatatt caatcgacag cagcttatca atcattgaca agtgagcaac aaactgagat
    20821 aagtgattct gtatctcaaa attcaactga tagtattcaa tcggctcagt caattgtagc
    20881 tttagtacaa gatttacagg gaagtttaga aaacttacaa aatcaatctt ctaatctttc
    20941 gactttaaaa aatcaatcta atcaagtatc acctattact tctacttctt tgataggatt
    21001 gtcaagtgga ttaacagaga tacaaggaga tgttactagc aaattagttc ctgccagtca
    21061 gtcgattgca tcaggtgtaa acgcatatac tacaggtgtt gataaagttt ctcagggcgc
    21121 aagtcaacta agtgaaaaaa atgccacctt gacaggtagt ttggataaac tagtttcagg
    21181 ctcaaacacc ttgacacaaa aatcttctag attgacagca ggagttggtt aattacaatc
    21241 aggatctggg caattagcag acaaatccag tcagttactt tcaggtgctt ctccattaga
    21301 gaatagagct aataaattgg cagatggatc taggaaacta gcagaaggtg gaacaaagtt
    21361 aacttctgga ttggaagatt tacagacagg acttgcttct ttaggacaag gactaggtaa
    21421 tgctagtgat caactcaaat cagtatcaac agaatctaaa aatgcagaga ttttgtcaaa
    21481 tccactcaat ctttcaaaaa cagacaatga tcaagttcct gtaaatggaa tcgcaatagc
    21541 tccttatatg atatcagttg ctcttttttt tgcagcaata tcaacaaata tgatatttgc
    21601 gaaattgcct tcaggacgtc atccagagag ccgttgggct tggttgaaat cttgagctga
    21661 aataaatggt attatagctg ttttggcagg aattttggta tatggaggag ttcagcttat
    21721 tggtttaact gctaatcatg agatgagaat atttattctc atcatcctaa caagtttagt
    21781 attcatgtct atggtgacca ctttagcaac gtggaatagc cgtataggag cttttttctc
    21841 acttattttg cttttactac agttagcatc aagtgcaggt acttatccac ttgctttgac
    21901 aaatgatttc tttagatcta ttaatccctg gttaccaatg agctattcag tttcgggatt
    21961 acgacaaaca atctctatca acaagtcatt ttcctagctg tcatactagc tctatttact
    22021 ggtttaggta tgctagccta tcaacataag aaaatggaag aagattaaaa aaatcgaccg
    22081 attaactggt cgatttttta tgccttagat gactttcgtc tgtgattata gattccaaat
    22141 agtaagagag aagtaaagga acagattgct ccagtaataa aaccattggg aatgaaggaa
    22201 agtgtaatag ttcctttccc cttgggaatg tcaactttca taaatccagt ttgagcttgt
    22261 ttaatttcta ttttcttacc atcttggtag gcagaccaac ctttgtcata aggaatggtg
    22321 aagaaaatag atgtatcttg ttggacatca tatgtagcaa aaaccttgtt tttagaagtt
    22381 gatactgtga caggttgttc tttaattttt tgaattgcct cggtgaaagt tttggtatct
    22441 aaacgataga aggtaggaga ttcaaatgat acttgtgaat ttccagggaa actaacattg
    22501 atattgaaag tttttttctc tttagtatat cctagattaa agaaggagaa gacattatca
    22561 gttgtaaaag tctttttttc accatttaca aggatgtcaa ccttcttttg tttatcgtta
    22621 gaaaagtgaa ggtttatgaa agagagataa acttggctgt tttctggaac ttcaatttga
    22681 tactggattg ctgcatcttc atttgaagaa cttgtgacac taatcaaatc attagtattt
    22741 tctatttttt ctgttttttc ataaggtatt ggagaaaaat aatcaaaatt gacgttagca
    22801 agttgattta aaaatgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg
    22861 taaacagatt gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga
    22921 ttatcttttt gatagatatc tttaaagcca tacttatcaa taggactgtc tgagatattg
    22981 tactggatac caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga
    23041 ttagtcccag aggatttaaa accaagttta tctaaagtag agcttgatga acgatttcga
    23101 acagatgaaa attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga
    23161 gtttgtagtt tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata
    23221 gctaggatat ctcgactata agcacttcga gaagcaaatc cccattcctt agcaattccg
    23281 tccatttgag atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg
    23341 gcaaatagat tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca
    23401 accaaaaatt caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt
    23461 agatagatgg tagctaaaaa tcctgctact acaagaaaaa gcgaaactaa aaaattccag
    23521 actttaagtt ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag
    23581 aaaatccaag catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag
    23641 tcaagagctt ctatgtaaaa gcttgcaatt agaaatgcaa agaatattac atatatgagt
    23701 ttcacgtgaa acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaagggaaat
    23761 agtccaacaa aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat
    23821 tgcttagcaa agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc
    23881 aatttttccc catgtgtctg taaatcaaat agagtgggaa gagtcataat caaactagcc
    23941 ataccagcta aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag
    24001 tcccacgaaa tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa
    24061 taataatttt gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca
    24121 gttatcagta gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag
    24181 gtttttatct ctaattgact gacagtgaaa ctcatcagag cataggaagt agataaggct
    24241 agttttaaag tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga
    24301 ccaatcaatc caaattttaa gagagtggtc agatagacag catctggcat gttcgttaga
    24361 tcaaaaaagt aaactagagg cgcgagaaaa ctacccaagt aataactaga tagggcatag
    24421 aagtttagcc ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata
    24481 tttcgtaagg ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag
    24541 ttgtcgctat tccagtagat accttgagat agatatactc cagacataat cactacagga
    24601 atgatgagag aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt
    24661 agaatgatag aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt
    24721 ccaaagttct ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc
    24781 atcgatacgg tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg
    24841 aataaattcg tggtcatggc tagcaaagat gattgattct ttaaagtttt tcaatccatc
    24901 attcaagctt gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac
    24961 atttgatttt aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa
    25021 gacatttaca ggtttgttaa cttcatctcc agagaagagc atacggccga ggaagccacg
    25081 taggaaagta ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga
    25141 ttctcctcct gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac
    25201 tccccacttg acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt
    25261 cgtttgaata tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact
    25321 aatattatcc aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag
    25381 atcattacca atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg
    25441 tacaatctct tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga
    25501 cttagaagca ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc
    25561 tgctttagca ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa
    25621 gtcgtagttt ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca
    25681 aactttgttt aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat
    25741 caagaagtct tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa
    25801 gagaagaaca tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc
    25861 gttggccaat tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag
    25921 tagttgagag gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag
    25981 ttcggcagca cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt
    26041 ctctttcatg atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc
    26101 atcttcgtag tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga
    26161 gatgtgacca gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc
    26221 ggcaccatta gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc
    26281 atcaaaaagt ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt
    26341 tctcctatat gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat
    26401 ttgtcaattt tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag
    26461 gctgatttat tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac
    26521 tatatcgaag gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg
    26581 aaaattgcat attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga
    26641 ggataagtat gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa
    26701 agatcctcaa accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg
    26761 attggatcca aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt
    26821 gtctatgtat tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa
    26881 gacagagatt tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc
    26941 aatcgctcaa gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga
    27001 tcagaaacca atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa
    27061 ctgtgatgtc ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt
    27121 gcctggttta gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc
    27181 tgatgatgcg gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat
    27241 ccgcgttgag gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt
    27301 tggtcgtcca gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg
    27361 tcttggtgat gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc
    27421 tattcgtgag cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca
    27481 aaaaggtagt gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc
    27541 aatgggactt cattacttta actaagttta ttttacaaga aactatcatt tctatctcga
    27601 agaaaagata gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg
    27661 atagatacaa tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt
    27721 ctaattggga cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc
    27781 cagctgaaag tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt
    27841 tgactttaaa tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg
    27901 ccattgctat tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc
    27961 aacaagcaga cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt
    28021 tcttcttgac gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca
    28081 tcagtggtgt tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa
    28141 accgagatct tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg
    28201 aaaatcttgt tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag
    28261 agcatcgtat tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca
    28321 ctatcaaaga tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gaatttggtc
    28381 gtcttctagt tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc
    28441 tttttgaggc aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg
    28501 tcttgcgtaa aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa
    28561 atattgctac tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg
    28621 ttggtattgg accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc
    28681 aagtaacagc tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg
    28741 ctgacggtgg gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg
    28801 ctgttatgct tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct
    28861 tccaaggacg taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag
    28921 gttcaagcga ccgttatttc caaggttctg tcaatgaagc aaacaagctc gttccagaag
    28981 gaattgaagg tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg
    29041 gtggtattcg ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata
    29101 atgctcaatt tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc
    29161 aaattactaa tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga
    29221 aaacaggagt tcttttacaa tgttgtcaat ttccatttac agaagcttta ccatcctgaa
    29281 tagtgaagat acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga
    29341 taaaggtttg gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa
    29401 gttcactcat cacatcgtca agcagtaata taggagattc tgtggtaatg ctttccatta
    29461 attcgatttc tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga
    29521 aactagcatc catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag
    29581 tattcttttt aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg
    29641 ataagttttg tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga
    29701 tctgattaga gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat
    29761 ctaagcggtg attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa
    29821 ggaatgtttc atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt
    29881 ggttataatt ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa
    29941 tgaattttcg tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata
    30001 agacaacatt catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt
    30061 ttgttacacg gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct
    30121 gaacgagacc tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc
    30181 gagttcgatg actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc
    30241 cttgtgcatt acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt
    30301 tgtaattacg aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa
    30361 tcgtggagct tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc
    30421 cttattcatc tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta
    30481 ttcatcttgt tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat
    30541 gtcaacttta tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa
    30601 gtaaacagaa tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag
    30661 ttctttgagt agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca
    30721 cctcaatctt tggtattata ccatattttc ctaaaaatag tgagagagac agcgagaaat
    30781 gtaagcgatt tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat
    30841 ataatagaag tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac
    30901 attttatcca atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat
    30961 tatcccttga tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc
    31021 agatgtaccc cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata
    31081 tgtcaaccaa ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg
    31141 ttcgtgatga gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa
    31201 aagaaactct tttttcaccc gcagtagttg ataatgggtt tgatccggcc ttatttgaaa
    31261 ttgagaaaaa acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg
    31321 cacataaaga attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg
    31381 atttacgaaa tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat
    31441 ttttagccaa tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc
    31501 aaaatgtatt agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt
    31561 gtcaacctta ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca
    31621 ttttggaatt aggttatcat taccgttcta aatatggtga tgagcaacat ttacccatga
    31681 ttgtaatgaa tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg
    31741 aaaatgctgg attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga
    31801 ggatgtatgc tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc
    31861 aactgcttga tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa
    31921 tgattcgttg gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt
    31981 atcaaaatgc cttatttgga aaatcttcag cagactttaa aagttggatt gcagagcttg
    32041 aacaaattga caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt
    32101 actttatgga aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt
    32161 aaaagaaaag gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa
    32221 aaaggaattt aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt
    32281 tgtcacagaa gttgacggat atgtaaaaca atatcctgga ggaattgctc attttcttga
    32341 acataaatta tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg
    32401 tgcagatagt aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga
    32461 ttatttttta gaaaatttag atttacttga tgaattggta acatcagcac actttactga
    32521 agcttccatt ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga
    32581 tccagattcg tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc
    32641 aactgatata gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga
    32701 aaattttaca aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga
    32761 tgtggagcga gtacaggact attttgaaag caaagaactg aaagattcag attttcagga
    32821 agtagcaaga gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga
    32881 agtatcttct cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga
    32941 ttgctatcga catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc
    33001 ggatcgtttt caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt
    33061 tgaaataaca agtcgctttc attttgtcat gttgacaata gatacgaaag agccagttgc
    33121 tttgtctcat caatttagga aggctattcg taattttaca aaggatttag atattacaga
    33181 ggaacattta gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc
    33241 tcttgaattt attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt
    33301 gccgaaaatt ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat
    33361 agatgatggt gacatagttg attttacaat attcccatcg tagtaaccta tcataataga
    33421 cactagaaag aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta
    33481 gctagaatca atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta
    33541 gatatgttgg aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg
    33601 cgttctttct tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat
    33661 gcttatgatt ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg
    33721 acaggtcgta gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt
    33781 tattttatcc tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat
    33841 attcaaactc aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt
    33901 tcaactagct ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata
    33961 agtgtatcag gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt
    34021 aaattgcaat tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt
    34081 gagggcggtg taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa
    34141 agtcctgtaa caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag
    34201 actgttgatt tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa
    34261 aattaaggaa aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat
    34321 tctctttata cctattttta tctttatttt aacgatagga aattcgatag agagtcatat
    34381 agttgcagct attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc
    34441 tcgtaaatgg aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt
    34501 actagttatg tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt
    34561 tgcagtgatt atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac
    34621 tggtggaaca attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt
    34681 tgctattatt ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc
    34741 cttatttttc actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa
    34801 agggacattt ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat
    34861 aaagaaaatc agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa
    34921 tggctttcga ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat
    34981 ggcttactgg aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa
    35041 aatgtttgga atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt
    35101 gttggagcga ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt
    35161 caagaaatga aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa
    35221 aagagagagc cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt
    35281 gtagccctaa gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag
    35341 gggcgtagag aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc
    35401 atttctatta cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa
    35461 aaaggggaaa ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat
    35521 caaattggat tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc
    35581 tatgatttac ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg
    35641 ctctagaaaa tgtgaatttt atatatcaag aaggtactcc cttagcttca gcagctttgt
    35701 cggatgtttc tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta
    35761 gtggtaaatc aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg
    35821 tgagggtttt tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta
    35881 gaaaacaggt tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt
    35941 tgaaggacgt tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga
    36001 ctgcgcgtga gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt
    36061 ttgagctgtc agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc
    36121 catctatatt agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt
    36181 tgatgaccct gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt
    36241 tgatggatga tgttgctgaa tatgctaatc aagtctatgt aatggaaaag ggacgtttag
    36301 taaagggggg caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt
    36361 tgggagtacc taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta
    36421 aacgattacc gattaagata gaggagttca aggagtcgct aaatggatag tatgattttg
    36481 gggcgttata tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt
    36541 gctatgatgc tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt
    36601 ctttttatag cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt
    36661 cagggcttga agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc
    36721 atttctaatg ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg
    36781 caacaagctg ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta
    36841 accttaacaa ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta
    36901 aagcgtgtga aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt
    36961 gtcccaacct tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg
    37021 gattttggag aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct
    37081 ctttttgcga caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc
    37141 tatcagggtg gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg
    37201 ctgaccattc ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag
    37261 ctttcaggaa ttgataaaaa gttactgtaa cagtttttga tataaaggta gggatatgaa
    37321 ccgttttaaa aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc
    37381 tctcttagcg acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt
    37441 ggttgataga gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc
    37501 tcatttgaca cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga
    37561 agttaaatca aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct
    37621 tgatatgaag tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc
    37681 tccggtatct tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga
    37741 gaacatgtta gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa
    37801 ctctactata gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat
    37861 tcaacatggc tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt
    37921 tcttaaaatt agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac
    37981 tggtggatta ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac
    38041 gcatagtaca gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa
    38101 tgtagatgtg atagaattag tggggaattc ataatgagac agttgaagcg agttggagta
    38161 tttttattgc ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca
    38221 tttttccccc atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg
    38281 atagaagtat cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat
    38341 gtttactttt tccatctaat agggattaca actctcttat ttatcttatt gggagccttc
    38401 cttcataaat tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt
    38461 gtgctgacat tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca
    38521 gtagatagca tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt
    38581 ttatggatta ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata
    38641 aatgtaacaa aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa
    38701 aagaaggagt atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca
    38761 gtaatggttt ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa
    38821 attgctgctc aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa
    38881 caagttgacc aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa
    38941 gctgaaaatg atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt
    39001 tctaaaaaca ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca
    39061 aatggagccg taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct
    39121 atttcacgtg ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa
    39181 caaaaggcag ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat
    39241 actgtaattg ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag
    39301 gcagaactaa aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa
    39361 aaagcaagtc tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta
    39421 gcagaagcag cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca
    39481 aacactaact taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt
    39541 gcaaaagttc gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca
    39601 tggggagtaa aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg
    39661 gctacaagtg cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt
    39721 gcatgttgga atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca
    39781 acacgtatcc aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt
    39841 ggatggttca atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa
    39901 tttacagagg gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa
    39961 aaattatatc aaaatagctt gaaaatattg gaaaagtatg gtagaatgaa aattgtcgtg
    40021 tgaacgataa tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga
    40081 gttgaagtca agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat
    40141 gaaacaactt cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa
    40201 gatggctaag tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac
    40261 tgtaaaatac gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt
    40321 tgtattgttc gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg
    40381 ttcaggtcaa tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac
    40441 aatccaaaaa cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt
    40501 cgaagttctt cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa
    40561 attcttgggc ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc
    40621 acataaagag caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat
    40681 ggttgacacc aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc
    40741 tatccgtgct gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca
    40801 aggtgaggat gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc
    40861 aattgaagaa atcgttgaag ttgtagaagg tgacaacgct taatttatac aaatagtaat
    40921 tacctaggag ggcggggctt agcccggctc tcctattttc aaaaaatata ggagaattaa
    40981 aatggcagaa attacagcta aacttgtaaa agagttgcgt gaaaaatctg gtgccggtgt
    41041 tatggacgct aaaaaagcgc ttgtagaaac agacggtgac atcgaaaaag cgattgaatt
    41101 gcttcgtgaa aaaggtatgg ctaaggcagc taagaaagct gaccgtgttg ctgcagaagg
    41161 tttgactggt gtttatgtta acggtaatgt tgcagcagtt attgaagtaa acgctgaaac
    41221 tgacttcgtt gcaaaaaacg ctcaattcgt tgaattggta aatactacag ctaaagtcat
    41281 tgctgaagga aaacctgcta ataatgaaga agctcttgct ttgataatgc cttcaggtga
    41341 aactcttgaa gctgcatacg tatctgcaac agcaactatc ggagagaaaa tctcattccg
    41401 tcgctttgca ttgattgaaa aaacagacgc acaacacttt ggagcatacc aacataacgg
    41461 tggacgtatc ggtgttattt cagttgttga aggtggagac gaagcacttg ctaaacaatt
    41521 gtcaatgcac atcgcagcga tgaaaccaac agttctttct tacaaagaat tggatgagca
    41581 attcgttaaa gatgagttgg cacaattgaa tcacgttatc gaccaagaca acgaaagccg
    41641 tgcaatggtt aataaaccag ctcttccaca cttgaagtat ggatcaaaag ctcaattaac
    41701 tgatgatgtt attgctcaag ctgaagctga catcaaagct gaattggctg cagaaggcaa
    41761 accagaaaaa atctgggaca aaattatccc aggtaaaatg gatcgcttca tgcttgataa
    41821 tactaaagtt gaccaagctt acacacttct tgcacaagtt tacatcatgg atgacagcaa
    41881 gacagttgaa gcataccttg aatcagttaa cgcttcggta gttgagtttg ctcgctttga
    41941 agttggtgaa ggtatcgaga aagctgcaaa cgacttcgaa gctgaagttg cagctacaat
    42001 ggcagcagcc ttgaataact aataatagaa aggaagcaat ttgcttcctt ttttgtatag
    42061 ggcttatatt tttcctgaaa ttgtttttcc cccagtctca ctcgattaga ataattaaaa
    42121 caaaaagccc tataataagg gctaagtgca tttaggagac tatacttcaa attcatagta
    42181 agcgcgtcat aacaaggtat ctatcctaat tccccaactt ccagtatact agataaaaaa
    42241 taattatcgg aggaaaggta ttgtactatg atgattcaac taagtgattt aggtcaagtt
    42301 cacattgttt gtggcaagac agatatgagg cagggaatag actcattagc ctatgtagtt
    42361 aaaacccact ttgaattgga ttctttctcc ggtcaagtct ttctcttttg tggtggacgt
    42421 aaagaccgct ttaaagtcct ttactgggat ggtcaaggat tttggctact atataaacgc
    42481 tttgagaacg gaaaactgac ttggctaagt acagaaaagg atgtcaaagc tctcgcacct
    42541 gaacaagtag actagcttat gaagggcttt tctatcactc caaaaatata gtagattgaa
    42601 actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgat
    42661 cgatttgtcc tgttcttatt tcattttact ataaatccat cagaaagtcg tgatttctat
    42721 tgaaatgagg actttctttt tacactcatc tgctttcaaa aagcattcta gtccgtctcc
    42781 gattaacgat ggactttatc acctccttct ctagtccttg tatgacatct tccaaagttc
    42841 gaaaggcttt attcttaaat ccacgtttac gaatctcttt ccacacttgt tcaatgggtt
    42901 catctctggt gtgtatggag gaataaaggt aaaaccaata ttagtcggaa tctttaaggt
    42961 acttgattta tgccatatag cattgtccat aacgagtaaa aaataatcat ctggatgctc
    43021 ctattcctaa agccccttta gcgcatagct ttggctcagc ttctattatc gctcacatca
    43081 tccatcagaa gtttaatctg aaggtaccca attatcgcca agaagaagat tgggctagga
    43141 tgggtttacc aatcacacgt aaggaaatct ctaatcggca tatcaagacg agtcaatact
    43201 atttggagcc cctttataac ctcttgcgag agagactatt gactcagccc ttacttcatg
    43261 cggatgaaac ttcttatagg gtgctagaga gtgatagtca gctgacttac tattggactt
    43321 ttttgtctgg gaaagctgag aaacaaggga ttacgcttta ccatcatgtc ctaatcgatt
    43381 tgttcatatc ttatttcaat ccattataaa tagtgagaaa tatctatcct atcttctaga
    43441 atgtcttcca aacgtggaaa ctctcgtaaa caaagaggtt ttagaggcct atttaccatg
    43501 gactaaagtt gtacaagaaa agtgcaaata agaaatctcc agattaggaa ctatccgtga
    43561 gttctctagt ctggagattt ttcaatagac ttcgttattg gacggttaca attcataaag
    43621 tgctgtagag agataacgtt caccgttatc tggtgctagg gcaaggactt ttttacctgt
    43681 acctaatttt ttggcaacct cgatggctcc gtagatagct gcagctgagg aaatccctac
    43741 aaggaagcct tcttttccac caatttcacg tccgagtgca agagcgtcat ctgatgttac
    43801 acgaacgata ccatcatagg ctttagtatc aagtgtatca ggaataaatc cagctgagat
    43861 accttgaatt ttgtgaggac caggtttttc accagataga atagcagatt catctgcttc
    43921 tactgcaaaa acttgaatgt tagaattttc tgatttgagt gcatgagaaa caccagaaat
    43981 cgttccacca gtacctactc cagcaacaaa ggcatctaat ccatctttac cgaaagcagc
    44041 tagtatctca gctcctgttg ttctttcgtg tacttctgga ttagctggat tgtcaaattg
    44101 aagaggaagg aaaccatcac gttcagcagc gatttcttga gccttagcaa tagcaccttt
    44161 cattccctcg ctaccaggag ttaggacgag ttcagcacca taagcttgga taattttacg
    44221 tcgttctaca ctcatagttt caggcataac gatgacgact ttataccctt tagcagcacc
    44281 tacccatgaa agtccaatac cggtgtttcc acttgttgct tcaacaatag tagaaccaag
    44341 tttcagaata ccatcttgtt cagctttttc aatcatgcta agggcaatac ggtcttttac
    44401 agatgaacca ggattaaatg cttcaagctt tatatagacg tctgcagcac cttctggcac
    44461 gatgttgtta agtttaacaa tcggtgtttg accgattaat tcagtaatgt tgttataaat
    44521 agacatatga atacctcttt gtataagata tctttagtat aacgctatcc ataccatttg
    44581 taaaatatag aaatcctatc gaagcgatag gatttctata tatcatagat caaagtcatt
    44641 aattttcaag tgattgcgtt cagttaattc tagtaaatag gtgtgaagga aaacgatatc
    44701 aggtttcgtt tgaattgctt cattttctag tatattttgg tacgcatctt tttattttgc
    44761 tcgctaaagt agttgtgaga atgtcaacga aacgctgtat tattcattgt ttacactaag
    44821 tttacaggaa cttcaacctc tcgtaaacct tggtcagtta aagtgacttt tccattaaaa
    44881 aactccacaa gtgcagcttt aatagtttct ttttcttctt tatcaacata aatcatcgta
    44941 tcgacttgat ctgtaaagtt tgtatccagc tccatgagat catgttcttt aaggaagtta
    45001 ctgtactctt ggtactgagc ataagacatt tgaatagcaa tgccagcctg ttcttttatt
    45061 tcaataatac caatttcttt gacagctaag gcgacactgc cggcgtaagc acgaattagt
    45121 cctccagcgc ctagtttaat accaccaaag tagcgtgtca cgaccacaca gacattggtg
    45181 agattgtgat tttctagtac cccaagcatg ggaacaccag cagtaccact aggctcacca
    45241 tcatcacttg tacgtttaat ttcactacgt tctccaataa taaaggcaga gcagttatgt
    45301 gtcgctttgt agtgttcttt tttgatggca gtaatgaagt cacgagcctc ttcttcgcta
    45361 taaacacgct tggcatggca gataaagcga gattttttga tttcttcttg gacttggccg
    45421 tcctctttaa ttgtcctaaa ttccatgatt taattgtact aaaaaatcat ctaaagtgct
    45481 agtttttacg aataaagaag tatgaaagta aatttagatt atctcggtcg tttatttact
    45541 gagaatgaat taacagaaga agaacgtcag ttggcggaga aacttccagc aatgagaaag
    45601 gagaagggga aacttttctg tcaacgttgt aatagtacta ttctagaaga atggtatttg
    45661 cccatcggtg cttactattg tcgagagtgc ttgctgatga agcgagtcag aagtgatcaa
    45721 actttatact attttccgca ggaggatttt ccgaagcaag atgttctcaa atggcgcggc
    45781 caattaactc cttttcaaga gaaggtgtca gagggactgc ttcaagcagt agacaagcaa
    45841 aagccaacct tagttcatgc ggtaacagga gctggaaaga cagaaatgat ttatcaagta
    45901 gtggctaaag tgatcaatgc gggtggtgca gtgtgtttgg ctagtcctcg catagatgtt
    45961 tgtttggagc tgtacaagcg cctgcaacag gatttttctt gcggaatagc tttgctacat
    46021 ggagaatcgg aaccttattt tcgaacacca ctagttgttg caacaaccca tcagttattg
    46081 aagttttatc aagcttttga tttgctgata gtggatgaag tagatgcttt tccttatgtt
    46141 gataatccca tgctttacca cgctgtcaag aatagtgtaa aggagaatgg attgagaatc
    46201 tttttaacag cgacttcgac caatgagtta gataaaaagg tccgtttagg agaactaaaa
    46261 agactgaatt taccgagacg gtttcatgga aatccgttga ttattccaaa accaatttgg
    46321 ttatcggatt ttaatcgcta cttagacaag aatcgtttgt caccaaagtt aaagtcctat
    46381 attgagaagc agagaaagac agcttatccg ttactcattt ttgcttcaga aattaagaaa
    46441 ggggagcagt tagcagaaat cttacaggag caatttccaa atgagaaaat tggctttgta
    46501 tcttctgtaa cagaggatcg attagagcaa gtacaagctt ttcgagatgg agaactgaca
    46561 atacttatca gtacgacaat cttggagcgt ggagttacct tcccttgtgt ggatgttttc
    46621 gtagtagagg ccaatcatcg tttgtttacc aagtctagtt tgattcagat tggtggacga
    46681 gttggacgaa gcatggatag accgacagga gatttgcttt tcttccatga tgggttaaat
    46741 gcttcaatca agaaggcgat taaggaaatt cagatgatga ataaggaggc tggtctatga
    46801 agtgcttgtt atgtgggcag actatgaaga ctgttttaac ttttagtagt ctcttacttc
    46861 tgaggaatga tgactcttgt ctttgttcag actgtgattc tacttttgaa agaattgggg
    46921 aagagaactg tccaaattgt atgaaaacag agttgtcaac aaagtgtcaa gattgtcaac
    46981 tttggtgtaa agaaggagtt ggagtcagtc atagagcgat ttttacttac aatcaagcta
    47041 tgaaggattt tttcagtcgg tataagtttg atggagactt cctgttaaga aaagttttcg
    47101 cttcattttt aagtgaggag ttgaaaaagt acaaagagta tcaatttgtt gtaattcccc
    47161 taagtcctga tagatatgct aatagaggat ttaatcaggt tgagggcttg gtagaggcag
    47221 caggctttga gtatctagat ttattagaga aaagagaaga gagagccagt tcttctaaaa
    47281 atcgttcaga gcgcttgggg acagaacttc ctttctttat taaaagtgga gtcactattc
    47341 ctaaaaaaat cctacttata gatgatatct atactacagg agcaactata aatcgtgtta
    47401 agaaactgtt ggaagaagcc ggtgctaagg atgtaaaaac attttccctt gtaagatgag
    47461 gaaaaaattt gcaaaaatag aatgaaagcg ttataataaa atcataaaaa caaaaatgtt
    47521 tagaaagaag gtactcatat gattaaatat agtatccgtg gtgaaaacct agaagtaaca
    47581 gaagcaattc gtgattatgt agtttctaaa ctcgaaaaga tcgaaaagta cttccaacca
    47641 gaacaagagt tggatgcccg aattaactta aaagtttatc gtgaaaaaac ggctaaagtg
    47701 gaagtaacga ttccgcttgg atctattact ctccgcgcag aagatgtatc tcaagatatg
    47761 tatggttcaa ttgaccttgt aactgataaa attgaacgtc agattcgtaa aaataaaaca
    47821 aaaatcgagc gtaaaaataa aaataaggta gcaactggtc aattatttac agatgctttg
    47881 gtggaagatt caaatattgt ccagtctaaa gttgttcgtt caaaacaaat tgatttaaaa
    47941 ccaatggatt tggaagaagc aattctacaa atggatttat tggggcatga tttctttatc
    48001 tatgtggatg ttgaagatca gacaaccaat gtgatttatc gtcgtgagga tggcgaaatt
    48061 ggtttgttag aggttaaaga atcttaattt caatatgtgt aaaggtaggt ttactgaatt
    48121 gtaaactacc tttttcttat aattgataga attactgatt acacttttaa aaagtcgctt
    48181 tttgaggggt attatggtat aatgggtgcc aagaggtttt gaatgaaaaa attttatgta
    48241 agtccaattt ttcctattct agtaggattg attgcgtttg gagtcttatc cactttcatt
    48301 atttttgtta ataataatct gttgacggtt ttaattttgt ttctttttgt aggaggctat
    48361 gtttttttat ttaagaaact gagagtgcat tatacaagga gtgatgtaga acagatacag
    48421 tatgtaaacc accaagcgga agaaagtttg acagctctat tggaacagat gcctgtaggt
    48481 gttatgaaat tgaatttatc ttctggagag gttgagtggt ttaatcccta tgctgaattg
    48541 attttgacca aggaagatgg tgattttgat ttagaagctg ttcaaacgat tatcaaggct
    48601 tcagtaggaa atccgtctac ttatgccaag cttggtgaga agcgttatgc tgttcatatg
    48661 gatgcttctt ccggtgtttt gtattttgta gatgtatcca gggaacaagc cataacagat
    48721 gaattggtaa caagtcgacc agtgattggg attgtctctg tggataatta tgatgatttg
    48781 gaggatgcaa cttctgagtc agatattagt caaatcaata gttttgtagc taattttata
    48841 tcagagtttt cagaaaaata catgatgttt tctcgtcggg taagtatgga tcgattttat
    48901 ctatttactg actacacggt gcttgagggc ttgatgaatg ataaattttc tgttattgat
    48961 gctttcagag aagagtcgaa acagagacag ttgcccttga ctttaagtat gggattttct
    49021 tatggcgatg gaaatcatga tgagataggg aaagttgctt tgctcaattt gaacttggct
    49081 gaagtacgtg gtggcgacca ggtggttgtt aaggaaaacg acgaaacgaa aaatccagtt
    49141 tattttggtg gtgggtctgc tgcttcaatc aagcgtacac ggactcgtac gcgcgctatg
    49201 atgacagcta tttcagataa gattcggagt gtagatcagg tttttgtagt cggtcacaaa
    49261 aatttagaca tggatgcttt gggctctgct gtaggtatgc agttgttcgc cagcaatgtg
    49321 attgaaaata gctatgctct ttatgatgaa gaacaaatgt ctccagatat tgaacgagct
    49381 gtttcattca tagaaaaaga aggagttacg aagttgttgt ctgttaagga tgcaatgggg
    49441 atggtgacca atcgttcttt gttgattctt gtagaccatt caaagacagc cttaacatta
    49501 tcaaaagaat tttatgattt atttacccaa accattgtta ttgaccacca tagaagggat
    49561 caggattttc cagataatgc agtcattact tatatcgaaa gtggtgcaag tagtgccagt
    49621 gagttggtaa cggaattgat tcagttccag aattctaaga aaaatcgttt gagtcgtatg
    49681 caagcaagtg ttttgatggc tggtatgatg ttggatacta aaaatttcac ctcgcgagta
    49741 actagtcgga catttgatgt tgctagctat ctcagaacgc gcggaagtga tagtattgct
    49801 atccaggaaa ttgctgcgac agattttgaa gaatatcgtg aggttaatga acttatttta
    49861 caggggtgta aattaggttc agatgtacta atagcagagg ctaaggacac gaaatgctat
    49921 gatacagttg ttattagtaa ggcagcagat gccatgttag ccatgtcagg tattgaagcg
    49981 agttttgttc ttgcgaagaa tacacaagga tttatctcta tctcagctcg aagtcgtagt
    50041 aaactgaatg tacaacggat tatggaagag ttaggcggtg gaggccactt taatttggca
    50101 gcagctcaaa ttaaagatgt aaccttgtca gaagcaggtg aaaaactgac agaaattgta
    50161 ttaaatgaaa taaaggaaaa ggagaaagaa gaatgaaagt aatcttttta gcagatgtta
    50221 aaggaaaagg taaaaaaggc gaaattaagg aagtaccaac agggtatgcg caaaactttc
    50281 ttatcaaaaa gaatctagcc aaagaagcga ctgctcaagc tgtaggtgaa cttcgtggta
    50341 aacaaaaatc ggaagaaaaa gctcacgctg agatgattgc agaaggaaaa gcaattaaag
    50401 cacaacttga agcagaagaa actgttgtag aatttgttga aaaagttggt ccagatggtc
    50461 gtacctttgg ttctattacc aataagaaga ttgcagaaga attgcaaaag caatttggaa
    50521 ttaagattga taaacgtcat attcaagtac aagctccgat tcgagcggtt ggtttgattg
    50581 atgtgccagt gaaaatctat caagatatca caagtgtaat caatcttcgt gtgaaagaag
    50641 gataagttta caccttcttg acaagattgt aaaaggaagg gaagtctgat ggcagaagta
    50701 gaagagttac gagtacaacc tcaagatatc ttagctgagc aatccgtttt aggggctatc
    50761 tttattgatg agagtaaact tgtttttgtg cgagaataca ttgagtctcg ggactttttt
    50821 aagtatgccc atcgtttgat tttccaagcc atggtcgatt tatccgatcg tggtgatgcc
    50881 atagatgcaa caacggttcg tactatcctt gataatcaag gtgatttaca gaatattggt
    50941 ggcttgtctt acttggttga gattgttaat tctgtgccaa cttctgctaa tgcggagtat
    51001 tatgctaaga ttgttgcaga aaaagcaatg ctacgtcgtt taattgccaa gttgacagag
    51061 tctgtcaacc aagcttacga agcgtcacaa ccagctgatg aaattattgc tcaggcagaa
    51121 aaagggttga ttgatgtcag tgaaaatgca aatcgaagcg ggtttaagaa cattcgagat
    51181 gtgttgaatc tcaactttgg aaatctggaa gctcgctcgc aacaaacgac cgatattaca
    51241 ggtattgcga caggttatcg tgatttggat catatgacaa caggacttca tgaggaggag
    51301 ttgattatct tagcagctcg tccagcagtt ggtaagacag catttgcctt gaatatcgct
    51361 cagaatattg ggactaagtt ggacaaaacg gttgctattt tttcactcga aatgggtgcg
    51421 gaaagcttgg tagaccgtat gttagctgca gaaggcttgg tggagtcaca ttctatccgt
    51481 acagggcaat tgacagatga ggagtggcaa aaatatacta ttgctcaggg taatctagct
    51541 aacgccagta tctatatcga tgatacgcca ggtattcgga ttacagagat tcgttctcgt
    51601 tctcgtaaat tggctcaaga aactggaaat cttggtttga ttttgataga ctatttgcaa
    51661 cttatcacgg gaactggtcg agaaaatcgt caacaagaag tttctgaaat ttctcgtcag
    51721 ttgaaaatac tagccaagga attgaaggtt ccagtaatcg ctctgagtca gctttctcgt
    51781 ggtgtagaac aacgtcagga caagagaccg gtcttgtctg atattcgtga atctgggtct
    51841 attgagcagg acgctgatat cgtagctttt ctctatcgcg atgactacta tgaacgtggt
    51901 ggtgaagaag aggagggtat cccaaataat aaggtggaag ttattatcga gaaaaaccgt
    51961 agtggagctc gtggaacagt ggaattgatt ttccaaaaag aatacaataa attttcaagt
    52021 atctcaaaga gggaggcata agatgtcaga tgcatttaca gatgtagcca agatgaaaaa
    52081 aatcaaagaa gaaatcaagg cacatgaggg acaagtcgta gaaatgactt tggagaatgg
    52141 tcgtaagcgc caaaaaaata gattgggtaa gctaattgaa gtttatccat ccctatttat
    52201 tgtggagttt ggggatgtgg aaggagataa acaagttaat gtttacgttg aatcctttac
    52261 ttactcagat attcttacag aaaagaattt gattcattat cttgactaaa gtgagaaatt
    52321 ttctcacttt ttcttttttc tccgaataat ttaggtgaag gcaatcatcg ctttatatta
    52381 ttttttaagg aggaagaatg aaaattttac cgtttatagc aagaggaaca agttattact
    52441 tgaagatgtc agttaaaaag cttgttcctt ttttagtagt aggattgatg ctagcagctg
    52501 gtgatagtgt ctatgcctat tccagaggaa atggatcgat tgcgcgtggg gatgattatc
    52561 ctgcttatta taaaaatggg agccaggaga ttgatcagtg gcgcatgtat tctcgtcagt
    52621 gtacttcttt tgtagccttt cgtttgagta atgtcaatgg ttttgaaatt ccggcagctt
    52681 atggaaatgc gaatgaatgg ggacatcgtg ctcgtcggga aggttatcgt gtagataata
    52741 caccgacgat tggttccatt acttggtcta ctgcaggaac ttatggtcat gttgcctggg
    52801 tgtcaaatgt aatgggagat cagattgaga ttgaggaata taactatggt tatacagaat
    52861 cctataataa acgagttata aaagcaaaca cgatgacagg atttattcat tttaaagatt
    52921 tggatagtgg cagtgttggg aatagtcaat cctcagcttc aacaggcgga actcattatt
    52981 ttaagaccaa gtctgctatt aaaactgaac ccctagttag tgcaactgtg attgattact
    53041 attatcctgg ggagaaggtt cattatgatc agatacttga aaaagacggc tataagtggt
    53101 tgagttatac tgcctataat ggaagctatc gttatgttca attggaggct gtgaataaaa
    53161 atcctctagg taattctgtt ctttcttcaa caggcggaac tcattatttt aagatcaagt
    53221 ctgctattaa aactgaaccc ctagttagtg caactgtgat tgattactat tatcctggag
    53281 agaaggttca ttatgatcag atacttgaaa aagacggcta taagtggttg agttatacgg
    53341 cttataacgg aagtcgtcgc tatatacagc tagagggagt gacttcttca caaaattatc
    53401 agaatcaatc aggaaatatc tctagctatg gatccaataa tagttcaact gtcggttgga
    53461 agaaaataaa tggtagttgg tatcatttca aatcaaatgg ttctaaatca acaggatggc
    53521 tgaaagacgg ttctagctgg tattatttga aattatctgg tgaaatgcag acaggatggt
    53581 taaaggagaa tggctcgtgg tattatctgg gtagttcagg ggcaatgaaa acaggctggt
    53641 accaggtctc tggtaagtgg tattattctt actcttcagg cgccttagct attaatacga
    53701 cggtggatgg ctacagagta aacagtgatg gagaacgagt atagaaaatt ggagtaggag
    53761 aaatttcctg ctcttttctg taagcagttt ccttgacatt tttcttattt tgcgctatca
    53821 tatatacata taatatatgg gagtctgtgt acagtctgag aggaagtgtt aaacttcgac
    53881 cgcacctgat ctgggtaatg ccagcggagg gaacgatact tagtctaatt ttgcaccttt
    53941 tccatgtatg gtaaaggttt ttcttttttt taaaaggaaa acgagaagag gaggttctta
    54001 tgaaagcaag cattgccttg caagttttac ccctagcaca ggggattgat cggatagctg
    54061 ttattgatca ggtcattgct tatctgcaaa ctcaagaagt gacgatggta gtgacaccat
    54121 ttgaaacggt cttggaaggg gagtttgatg agcttatgcg cattctaaaa gaagcgctgg
    54181 aagtggcagt gcaggaggca gacaatgtct ttgccaatgt caaaataaat gtaggagaga
    54241 ttttaagtat tgatgagaaa cttgaaaagt atactgagac gacacattag tctattgggc
    54301 tttctcggag tattgtcaat ctggcagtta gcaggttttc ttaaacttct ccccaagttt
    54361 atcctgccga cacctcttga aattctccag ccctttgttc gtgacagaga atttctctgg
    54421 caccatagct gggcgacctt gagagtggct ttactggggc tgattttggg agttttgatt
    54481 gcctgtctta tggctgtgct catggatagt ttgacttggc tcaatgacct gatttaccct
    54541 atgatggtgg tcattcagac cattccgacc attgccatag ctcctatcct ggtcttgtgg
    54601 ctgggttatg ggattttgcc caagattgtc ttgattatct taacaacaac ctttcccatc
    54661 atcgttagta ttttggacgg ttttaggcat tgtgacaagg atatgctgac tttgtttagt
    54721 ctgatgcgag caaacccttg gcaaatcctg tggcatttta aaatcccggt tagcctgcct
    54781 tacttttatg caggtctgag ggtcagtgtc tcctacgcct ttatcacaac tgtggtatct
    54841 gagtggttgg gaggttttga aggtcttggt gtttatatga ttcagtctaa aaaactgttt
    54901 cagtatgata ccatgtttgc cattattatt ctggtgtcga ttatcagtct tttgggtatg
    54961 aagctggtcg atatcagtga aaaatatgtg attaaatgga aacgtactta aaatagagcg
    55021 tttttgaaaa agaaaagagg aaatcaaaat gaagaaaaca tggaaagtgt ttttaacgct
    55081 tgtaacagct cttgtagctg ttgtgcttgt ggcctgtggt caaggaactg cttctaaaga
    55141 caacaaagag gcagaactta agaaggttga ctttatccta gactggacac caaataccaa
    55201 ccacacaggg ctttatgttg ccaaggaaaa aggttatttc aaagaagctg gagtggatgt
    55261 tgatttgaaa ttgccaccag aagaaagttc ttctgacttg gttatcaacg gaaaggcacc
    55321 atttgcagtg tatttccaag actacatggc taagaaattg gaaaaaggag caggaatcac
    55381 tgccgttgca gctattgttg aacacaatac atcaggaatc atctctcgta aatctgataa
    55441 tgtaagcagt ccaaaagact tggttggtaa gaaatatggg acatggaatg acccaactga
    55501 acttgctatg ttgaaaacct tggtagaatc tcaaggtgga gactttgaga aggttgaaaa
    55561 agtaccaaat aacgactcaa actcaatcac accgattgcc aatggcgtct ttgatactgc
    55621 ttggatttac tacggttggg atggtatcct tgctaaatct caaggtgtag atgctaactt
    55681 catgtacttg aaagactatg tcaaggagtt tgactactat tcaccagtta tcatcgcaaa
    55741 caacgactat ctgaaagata acaaagaaga agctcgcaaa gtcatccaag ccatcaaaaa
    55801 aggctaccaa tatgccatgg aacatccaga agaagctgca gatattctca tcaagaatgc
    55861 acctgaactc aaggaaaaac gtgactttgt catcgaatct caaaaatact tgtcaaaaga
    55921 atacgcaagc gacaaggaaa aatggggtca atttgacgca gctcgctgga atgctttcta
    55981 taaatgggat aaagaaaatg gtatccttaa agaagacttg acagacaaag gcttcaccaa
    56041 cgaatttgtg aaataatgac agaaattaga ctagagcacg tcagttatgc ctatggtcag
    56101 gagaggattt tagaggatat caacctacag gtgacttcag gcgaagtggt ttccatccta
    56161 ggcccaagtg gtgttggaaa gaccaccctc tttaatctaa tcgctgggat tttagaagtt
    56221 cagtcaggga gaattgtcct tgatggtgaa gaaaatccca aggggcgcgt gagttatatg
    56281 ttgcaaaagg atctgctctt ggagcacaag acggtgcttg gaaatatcat tctgcccctc
    56341 ttgattcaaa aggtggataa ggcagaagct atttcccgag cggataaaat tcttgcgacc
    56401 ttccagctga cagctgtaag agacaagtat cctcatgaac ttagcggtgg gatgcgccag
    56461 cgtgtagcct tactccggac ctaccttttt gggcacaagc tctttctctt agatgaggcc
    56521 tttagcgcct tggatgagat gacaaagatg gaactccacg cttggtatct tgagattcac
    56581 aagcagttgc agctaacaac cctgatcatc acgcatagta ttgaggaggc cctcaatctc
    56641 agcgaccgca tctatatctt gaaaaatcgc cctgggcaga ttgtttcaga aattaaacta
    56701 gattggtctg aagatgagga caaggaagtc caaaagattg cctacaaacg tcaaatcttg
    56761 gcagaattag gcttagataa gtagaaaaat agggagttgg tgaagattat cctttaccag
    56821 cgcccttttt cttttaaaaa tgagaaaatt tcggtataat agtcaaacaa ggtcaaggtt
    56881 taaagagaga ggtgggtttg ttatgagatt taaaaataca tcggatcata ttgaggccta
    56941 catcaaggcg attttagatc aatctggtat cgtggagttg caacggagtc agttggcaga
    57001 tacctttcag gttgttccta gtcagattaa ctacgtgatc aagacacgct ttacggaaag
    57061 tagaggctac ttggttgaaa gtaagcgtgg tggtggaggc tacattcgta taggacgaat
    57121 tgagttttct agtcatcatg aaatgctccg ggagctgctt tactcgattg gtgagcgagt
    57181 cagtcaagaa atttatgagg atattctcca gcttttggtt gagcaggaat tgatgaccaa
    57241 gcaggagatg aatttgctag aatcagtagc tttggatcgc gttttaggag aagaagctcc
    57301 agttgttcga gcaaacatgc tacgtcagat catacaagag gtagatagaa aagggaagta
    57361 agatgaacta ttcaaaagca ttgaatgaat gtatcgaaag tgcctacatg gttgctggac
    57421 attttggagc tcgttatcta gagtcttggc acttgttgat tgccatgtct aatcacagtt
    57481 atagtgtagc aggggcaact ttaaatgatt atccgtatga gctggaccgt ttagaagagg
    57541 tggctttgga actgactgaa acggactata gccaggatga aacttttacg gaattgccgt
    57601 tctcccgtcg tttgcagatt ctttttgacg aagcagagta tgtagcgtca gtggtccatg
    57661 ctaaggtgct agggacagag cacgtcctct atgcgatttt gcatgatggc aatgccttgg
    57721 cgactcgtat cttggagagg gctggttttt cttatgaaga caagaaagat caggtcaaga
    57781 ttgctgctct tcgtcgaaat ttagaagaac gggcaggctg gactcgtgaa gatctcaagg
    57841 ctttacgcca acgccatcgt acagtagctg acaagcaaaa ttctatggcc aatatgatgg
    57901 gcatgccgca gactcctagt ggtggtctcg aggactatac gcatgatttg acagagcaag
    57961 cgtgttctgg caagttagaa ccagtcatcg gtcgggacaa ggaaatctca cgtatgattc
    58021 aaatcttgag ccggaagact aagaacaacc ctgtcttggt tggggatgct ggtgtcggga
    58081 aaacagctct ggcgcttggt cttgctcagc gtattgctag tggtgacgtg cctgcggaaa
    58141 tggctaagat gcgcgtgtta gaacttgatt tgatgaatgt cgttgcaggg acacgcttcc
    58201 gtggtgactt tgaagaacgc atgaataata tcatcaagga tattgaagaa gatggccaag
    58261 tcatcctctt tatcgatgaa ctccacacca tcatgggttc tggtagcggg attgattcga
    58321 ctctggatgc ggccaatatc ttgaaaccag ccttggcgcg tggaactttg agaacggttg
    58381 gtgccaccac tcaggaagaa tatcaaaaac atatcgaaaa agatgcggct ctttctcgtc
    58441 gtttcgctaa agtgacgatt gaagaaccaa gtgtggcaga tagtatgact attttacaag
    58501 gtttgaaggc gacttatgag aaacatcacc gtgtacaaat cacagatgaa gcggttgaaa
    58561 cagcggttaa gatggctcat cgttatttaa ccagtcgtca cttgccagac tctgctatcg
    58621 acctcttgga cgaagcagca gcaacagtgc aaaataaggt aaagtatgta aaagcagacg
    58681 attcagattt gagtccagct gataaggccc tgatggatgg caagtggaaa caggcagccc
    58741 agctaatcgc aaaagaagag gaagtacctg tctacaaaga cttggtgaca gagtctgata
    58801 ttttgaccac cttgagtcgc ttgtcaggaa tcccagttca aaaactgact caaacggatg
    58861 ctaagaagta tctaaatctt gaagcagaac tccataaacg tgtcatcggt caagatcaag
    58921 ctgtttcaag cattagtcgt gcgattcgcc gtaatcagtc aggaattcgc agtcacaagc
    58981 gtccgatcgg ttcctttatg ttcctaggac ccacaggtgt cggtaagacc gagttggcca
    59041 aggctttggc agaagttctc tttgatgacg aatcagccct tatccgcttt gatatgagtg
    59101 agtatatgga gaaattcgca gccagccgtc taaatggagc tcctccaggc tatgtgggtt
    59161 acgaagaagg tggagagttg acagagaagg ttcgcaataa accctattcc gttctcctct
    59221 ttgatgaggt agagaaggcc cacccagata tctttaatgt tctcttgcaa gttctggatg
    59281 acggtgtttt gacagatagc aagggacgca aggtcgattt ttcaaatacc attatcatta
    59341 tgacatcgaa cctaggtgcg actgcccttc gtgatgataa gactgttggt tttggggcta
    59401 aggatattcg ttttgaccag gaaaatatgg aaaaacgcat gtttgaagaa ctgaaaaaag
    59461 cttatagacc ggaattcatc aaccgtattg atgagaaggt ggtcttccat agcctatcta
    59521 gtgaccatat gcaggaagtg gtgaagatta tggtcaagcc tttagtggca agtttggctg
    59581 aaaaaggcat tgacttgaaa ttacaagctt cagctctgaa attgttagca aatcaaggat
    59641 atgacccaga gatgggagct cgcccacttc gcagaaccct gcaaacagaa gtggaggaca
    59701 agttggcaga acttcttctt aagggagatt tagtggcagg cagcacactt aagattggtg
    59761 tcaaagcagg ccagttaaaa tttgatattg cataaaagaa taaaagtatc agcatctgac
    59821 cataagtcac agtggagtga aactcaatga aaatcaaaga gcaaactagg cagctagccg
    59881 caggttgctc aaaacactgg tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    59941 ttcgaagagt atgaaactaa aacctatagc ttctaaacga tccgtggttt tcaccattca
    60001 acacaaaatt catatgttta ttaccctccg tcgtatttgt cttagagcgt gtgtagtaga
    60061 aaaagagcag tcttatctga aatttttatt ctttcaaaag agacctgttt cttttttgca
    60121 tgtcaaatcc gttctagctg gtatttgaaa aatcaaacta atattcaatg aaaatcaaag
    60181 aacaaactag gcagctagcc acaggttgct caaaacactg tttttagatt gtagatagag
    60241 ctgacgtggt ttgaagagat tttcgaagag tataagctgc aagatgaatg attttcttgt
    60301 attgacgttg ttgttgacaa aaagtagcgg ataaatgaaa tccattccat tatcatagat
    60361 gataggctgg taggaaattt tcaaatagca tacaggaaat agatgtatgg agttctggta
    60421 gtagaaaggg agagagatga acattttagt tgcagatgac gaggaaatga ttagagaagg
    60481 aattgcagca tttctgacag aagagggtta tcatgtcatt atggctaagg atggacaaga
    60541 ggtcttggaa aaatttcaag atctccctat ccatctcatg gtactggatt taatgatgcc
    60601 taggaagagt ggttttgaag tgttaaaaga aatcaatcaa aagcacgata ttcctgtcat
    60661 cgtcttgagt gctctgggag atgaaactac tcagtcacag gtatttgatc tctatgctga
    60721 tgatcatgtg acaaaacctt tttctttggt actgcttgtc aagcgtatta aggcgcttat
    60781 cagacgttac tacgtcatag aggatatttg gcgatatcag gatgtaacag tggattttac
    60841 ctcttacaaa gcacattata aaaatgaaga aattgatctc aaaccaaagg aattactggt
    60901 actaaagtgt ttgattcagc ataaaaatca agttttaagt agagagcaga tattggaaga
    60961 aatttcaaaa gatgtagctg atttaccttg tgatagggtc gttgatgtct atattcgtac
    61021 tcttcgcaaa aaattagctt tagattgtat cgtgactgtg aaaaatgttg ggtataagat
    61081 tagcttatga taaaaaatcc taaattatta accaagtctt ttttaagaag ttttgcaatt
    61141 ctaggtggtg ttggtctagt cattcatata gctatttatt tgacctttcc tttttattat
    61201 attcaactgg agggggaaaa gtttaatgag agcgcaagag tgtttacgga gtatttaaag
    61261 actaagacat ctgatgaaat tccaagctta ctccagtctt attcaaagtc cttgaccata
    61321 tctgctcacc ttaaaagaga tattgtagat aagcggctcc ctcttgtgca tgacttggat
    61381 attaaagatg gaaagctatc aaattatatc gtgatgttag atatgtctgt tagtacagca
    61441 gatggtaaac aggtaacagt gcaatttgtt cacggggtgg atatctacaa agaagcaaag
    61501 aatattttgc ttttgtatct cccatataca tttttggtta caattgcttt ttcctttgtt
    61561 ttttcttatt tttatactaa acgcttgctc aatcctcttt tttacatttc agaagtgact
    61621 agtaaaatgc aagatttgga tgacaatatt cgttttgatg aaagtaggaa agatgaagtt
    61681 ggtgaagttg gaaaacagat taatggtatg tatgagcact tgttgaaggt tattcatgag
    61741 ttggaaagtc gtaatgagca aattgtaaaa ttgcaaaatc aaaaggtttc ctttgtccgt
    61801 ggagcatcac atgagttgaa aaccccttta gccagtctta gaattatcct agagaatatg
    61861 cagcataata ttggagatta caaagatcat ccaaaatata ttgcaaagag tataaataag
    61921 attgaccaga tgagccactt attagaagaa gtactggagt cttctaaatt ccaagagtgg
    61981 acagagtgtc gtgagacctt gactgttaag ccagttttag tagatatttt atcacgttat
    62041 caagaattag ctcattcaat aggtgttaca attgaaaatc aattgacaga tgctaccagg
    62101 gtcgtcatga gtcttagggc attggataag gttttgacaa acttgattag taatgcaatt
    62161 aaatattcag ataaaaatgg gcgcgtaatc atatccgagc aagatggcta tctctctatc
    62221 aaaaatacat gtgcgcctct aagtgaccaa gaactagaac atttatttga tatattctat
    62281 cattctcaaa tcgtgacaga taaggatgaa agttccggtt tgggtcttta cattgtgaat
    62341 aatattttag aaagctatca aatggactat agttttctcc cttatgaaca cggtatggaa
    62401 tttaagatta gcttgtagac agattagttt tttattaaag ttcatatagg gttaacataa
    62461 gtgtgttatt ctttgcatag ataaaagaaa ggatactaat atggtattag cgattatttt
    62521 agtaacattc tttattcgat tgattttttt aaagcgttcg atagagaatg agaaacgaat
    62581 ccttagcaat ggcgggaaag aatttggagt tgagaataca aaacgattaa ctatggctca
    62641 tattgttttt tatctctctt gcttggttga ggcagtggtg cacaagacaa tttttgatgg
    62701 catgggtatg gttggtttgg tcttgcttat tttttctatg ctgatgttga tgttggtgat
    62761 tcacttgttg ggagatattt ggacagtgaa gcttatgctt gtcaataatc acaaatatgt
    62821 agatcatatc ttgtttagga cagtaaaaca tcctaattac tttttaaata ttcttcctga
    62881 gttgattggc ttgaccttgt tgagtcatgc ttatgtgact tttgttttag tttttccagt
    62941 ttatgcagtt attttgtatc gacgaatagc tgaagaggaa aagctattac atgaagttat
    63001 aatcccaaat ggaagcataa agagataaat acaaaattcg atttatatac agttcatatt
    63061 gaagtgatat agtaaggtta aagaaaaaat atagaaggaa ataaacatgt ttgcatcaaa
    63121 aagcgaaaga aaagtacatt attcaattcg taaatttagt attggagtag ctagtgtagt
    63181 agttgccagt cttgttatgg ggagtgtggt tcatgcgaca gagaacgagg gaagtaccca
    63241 agcagccact ttttctaata tggcaaataa aagtcagaca gaacaaggag aaatcaatat
    63301 agaacgagat aaggcaaaga cagcggtcag tgaatataaa gaaaaaaaag tgagtgagat
    63361 ctatacaaaa ttagagagag atagacataa agatactgta gatctagtta acaagttgca
    63421 agagattaag aacgagtatt tgaataaaat agttcaatca acctcaaaaa ccgaaataca
    63481 gggacttatt acaacaagtc gatcaaaact agatgaagct gtgtctaaat ataaaaaggc
    63541 cccatcttct tcgtcaagtt caggctcttc cactaaaccg gaagcttcag atacagcgaa
    63601 gccaaacaag ccgacagaac tagaaaaaaa ggtagcagaa gctgagaaga aggttgaaga
    63661 agctaagaag aaagccaagg atcaaaaaga agaagattac cgtaactacc caaccattac
    63721 ttacaaaacg cttgaacttg aaattgctga gtccgatgtg gaagttaaaa aagcggagct
    63781 tgaactagta aaagaggaag ctaaggaacc tcgaaacgag gaaaaagtta agcaagcaaa
    63841 agcgaaagtt gagagtgaag aaactgaggc tacaaggtta gaaaaaatca agacagatcg
    63901 taaaaaagca gaagaagaag ctaaacgaaa agcagcagaa gaagataaag ttaaagaaaa
    63961 accagctgaa caaccaaaac cagcgccggc tcctcaacca gaaaaaccag ctccaaaacc
    64021 agagaatcca gctccaaaac cagagaatcc agctccaaaa ccagaaaaac cagctgaaca
    64081 acaagctgaa gaagactatg ctcgtagatc agaagaagaa tataatcgct tgactcaaca
    64141 gcaaccgcca aaaactgaaa aaccagcaca accatctact ccaaaaacag gctggaaaca
    64201 agaaaacggt atgtggtact tctacaatac tgatggttca atggcgacag gatggctcca
    64261 aaacaatggc tcatggtact acctcaacag caatggcgct atggcgacag gatggctcca
    64321 aaacaatggt tcatggtact atctaaacgc taatggttca atggcaacag gatggctcca
    64381 aaacaatggt tcatggtact acctaaacgc taatggttca atggcgacag gatggctcca
    64441 atacaatgg
//
LOCUS       DAVBNN010000005        61611 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBNN010000005 DAVBNN010000000
VERSION     DAVBNN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.005"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(77..922)
                     /locus_tag="VQ847_000275"
     CDS             complement(77..922)
                     /locus_tag="VQ847_000275"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3049680.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1178..2046
                     /locus_tag="VQ847_000276"
                     /pseudo
     CDS             1178..2046
                     /locus_tag="VQ847_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2347..4236)
                     /locus_tag="VQ847_000277"
     CDS             complement(2347..4236)
                     /locus_tag="VQ847_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3049681.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4374..5939
                     /locus_tag="VQ847_000278"
     CDS             4374..5939
                     /locus_tag="VQ847_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3049682.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQILGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            5939..6679
                     /locus_tag="VQ847_000279"
     CDS             5939..6679
                     /locus_tag="VQ847_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3049683.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6788..7003)
                     /locus_tag="VQ847_000280"
     CDS             complement(6788..7003)
                     /locus_tag="VQ847_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049684.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(7874..9124)
                     /gene="ilvA"
                     /locus_tag="VQ847_000281"
     CDS             complement(7874..9124)
                     /gene="ilvA"
                     /locus_tag="VQ847_000281"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3049685.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(9174..9530)
                     /locus_tag="VQ847_000282"
     CDS             complement(9174..9530)
                     /locus_tag="VQ847_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3049686.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(9768..10004)
                     /locus_tag="VQ847_000283"
     CDS             complement(9768..10004)
                     /locus_tag="VQ847_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049687.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(10111..11133)
                     /gene="ilvC"
                     /locus_tag="VQ847_000284"
     CDS             complement(10111..11133)
                     /gene="ilvC"
                     /locus_tag="VQ847_000284"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3049688.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(11199..11675)
                     /gene="ilvN"
                     /locus_tag="VQ847_000285"
     CDS             complement(11199..11675)
                     /gene="ilvN"
                     /locus_tag="VQ847_000285"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3049689.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(11668..13368)
                     /locus_tag="VQ847_000286"
     CDS             complement(11668..13368)
                     /locus_tag="VQ847_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3049690.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(13569..15236)
                     /locus_tag="VQ847_000287"
     CDS             complement(13569..15236)
                     /locus_tag="VQ847_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3049691.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(15239..15604)
                     /locus_tag="VQ847_000288"
     CDS             complement(15239..15604)
                     /locus_tag="VQ847_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3049692.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(15761..15949)
                     /locus_tag="VQ847_000289"
     CDS             complement(15761..15949)
                     /locus_tag="VQ847_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3049693.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(16065..16550)
                     /locus_tag="VQ847_000290"
     CDS             complement(16065..16550)
                     /locus_tag="VQ847_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET3049694.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(16819..18363)
                     /locus_tag="VQ847_000291"
     CDS             complement(16819..18363)
                     /locus_tag="VQ847_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3049695.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            18576..18878
                     /gene="gatC"
                     /locus_tag="VQ847_000292"
     CDS             18576..18878
                     /gene="gatC"
                     /locus_tag="VQ847_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3049696.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            18878..20344
                     /gene="gatA"
                     /locus_tag="VQ847_000293"
     CDS             18878..20344
                     /gene="gatA"
                     /locus_tag="VQ847_000293"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3049697.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            20344..21786
                     /gene="gatB"
                     /locus_tag="VQ847_000294"
     CDS             20344..21786
                     /gene="gatB"
                     /locus_tag="VQ847_000294"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3049698.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            21910..22953
                     /locus_tag="VQ847_000295"
     CDS             21910..22953
                     /locus_tag="VQ847_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3049699.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            23331..23891
                     /gene="efp"
                     /locus_tag="VQ847_000296"
     CDS             23331..23891
                     /gene="efp"
                     /locus_tag="VQ847_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3049700.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            23913..24302
                     /locus_tag="VQ847_000297"
     CDS             23913..24302
                     /locus_tag="VQ847_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3049701.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            24295..24717
                     /gene="nusB"
                     /locus_tag="VQ847_000298"
     CDS             24295..24717
                     /gene="nusB"
                     /locus_tag="VQ847_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3049702.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(24767..25003)
                     /locus_tag="VQ847_000299"
     CDS             complement(24767..25003)
                     /locus_tag="VQ847_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3049703.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(25016..25489)
                     /locus_tag="VQ847_000300"
     CDS             complement(25016..25489)
                     /locus_tag="VQ847_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049704.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(25507..25692)
                     /gene="briC"
                     /locus_tag="VQ847_000301"
     CDS             complement(25507..25692)
                     /gene="briC"
                     /locus_tag="VQ847_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3049705.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(25851..26618)
                     /locus_tag="VQ847_000302"
     CDS             complement(25851..26618)
                     /locus_tag="VQ847_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3049706.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(26615..27481)
                     /locus_tag="VQ847_000303"
     CDS             complement(26615..27481)
                     /locus_tag="VQ847_000303"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3049707.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(27518..28885)
                     /gene="accC"
                     /locus_tag="VQ847_000304"
     CDS             complement(27518..28885)
                     /gene="accC"
                     /locus_tag="VQ847_000304"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3049708.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(28897..29319)
                     /gene="fabZ"
                     /locus_tag="VQ847_000305"
     CDS             complement(28897..29319)
                     /gene="fabZ"
                     /locus_tag="VQ847_000305"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3049709.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(29316..29801)
                     /locus_tag="VQ847_000306"
     CDS             complement(29316..29801)
                     /locus_tag="VQ847_000306"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3049710.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(29804..31039)
                     /gene="fabF"
                     /locus_tag="VQ847_000307"
     CDS             complement(29804..31039)
                     /gene="fabF"
                     /locus_tag="VQ847_000307"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3049711.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(31061..31792)
                     /gene="fabG"
                     /locus_tag="VQ847_000308"
     CDS             complement(31061..31792)
                     /gene="fabG"
                     /locus_tag="VQ847_000308"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3049712.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(31826..32746)
                     /gene="fabD"
                     /locus_tag="VQ847_000309"
     CDS             complement(31826..32746)
                     /gene="fabD"
                     /locus_tag="VQ847_000309"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3049713.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(32739..33713)
                     /gene="fabK"
                     /locus_tag="VQ847_000310"
     CDS             complement(32739..33713)
                     /gene="fabK"
                     /locus_tag="VQ847_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3049714.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(33832..34056)
                     /locus_tag="VQ847_000311"
     CDS             complement(33832..34056)
                     /locus_tag="VQ847_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3049715.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(34116..35090)
                     /locus_tag="VQ847_000312"
     CDS             complement(34116..35090)
                     /locus_tag="VQ847_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3049716.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(35090..35524)
                     /locus_tag="VQ847_000313"
     CDS             complement(35090..35524)
                     /locus_tag="VQ847_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3049717.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(35618..36403)
                     /locus_tag="VQ847_000314"
     CDS             complement(35618..36403)
                     /locus_tag="VQ847_000314"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3049718.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            36728..38092
                     /locus_tag="VQ847_000315"
     CDS             36728..38092
                     /locus_tag="VQ847_000315"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3049719.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            38095..38466
                     /locus_tag="VQ847_000316"
     CDS             38095..38466
                     /locus_tag="VQ847_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3049720.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            38680..39954
                     /gene="serS"
                     /locus_tag="VQ847_000317"
     CDS             38680..39954
                     /gene="serS"
                     /locus_tag="VQ847_000317"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3049721.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(39979..40878)
                     /locus_tag="VQ847_000318"
     CDS             complement(39979..40878)
                     /locus_tag="VQ847_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3049722.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(40988..41536)
                     /locus_tag="VQ847_000319"
     CDS             complement(40988..41536)
                     /locus_tag="VQ847_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3049723.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(41754..43076)
                     /locus_tag="VQ847_000320"
     CDS             complement(41754..43076)
                     /locus_tag="VQ847_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3049724.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(43167..43255)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(43419..45755)
                     /locus_tag="VQ847_000321"
     CDS             complement(43419..45755)
                     /locus_tag="VQ847_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3049725.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(45859..46407)
                     /locus_tag="VQ847_000322"
     CDS             complement(45859..46407)
                     /locus_tag="VQ847_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3049726.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(46404..46706)
                     /gene="zapA"
                     /locus_tag="VQ847_000323"
     CDS             complement(46404..46706)
                     /gene="zapA"
                     /locus_tag="VQ847_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3049727.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            46793..47665
                     /locus_tag="VQ847_000324"
     CDS             46793..47665
                     /locus_tag="VQ847_000324"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3049728.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            47677..48291
                     /gene="lepB"
                     /locus_tag="VQ847_000325"
     CDS             47677..48291
                     /gene="lepB"
                     /locus_tag="VQ847_000325"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3049729.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            48419..50785
                     /locus_tag="VQ847_000326"
     CDS             48419..50785
                     /locus_tag="VQ847_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3049730.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(50833..52116)
                     /locus_tag="VQ847_000327"
     CDS             complement(50833..52116)
                     /locus_tag="VQ847_000327"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3049731.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(52277..52669)
                     /locus_tag="VQ847_000328"
     CDS             complement(52277..52669)
                     /locus_tag="VQ847_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3049732.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(52968..53597)
                     /locus_tag="VQ847_000329"
     CDS             complement(52968..53597)
                     /locus_tag="VQ847_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3049733.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(53642..53881)
                     /locus_tag="VQ847_000330"
     CDS             complement(53642..53881)
                     /locus_tag="VQ847_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049734.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(54031..54297)
                     /locus_tag="VQ847_000331"
                     /pseudo
     CDS             complement(54031..54297)
                     /locus_tag="VQ847_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(54322..54633)
                     /locus_tag="VQ847_000332"
     CDS             complement(54322..54633)
                     /locus_tag="VQ847_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3049735.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(54558..54800)
                     /locus_tag="VQ847_000333"
     CDS             complement(54558..54800)
                     /locus_tag="VQ847_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3049736.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(54801..55433)
                     /locus_tag="VQ847_000334"
     CDS             complement(54801..55433)
                     /locus_tag="VQ847_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3049737.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(55447..56442)
                     /locus_tag="VQ847_000335"
     CDS             complement(55447..56442)
                     /locus_tag="VQ847_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3049738.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(56439..57137)
                     /locus_tag="VQ847_000336"
     CDS             complement(56439..57137)
                     /locus_tag="VQ847_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3049739.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(57214..58224)
                     /locus_tag="VQ847_000337"
     CDS             complement(57214..58224)
                     /locus_tag="VQ847_000337"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3049740.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(58208..59215)
                     /locus_tag="VQ847_000338"
     CDS             complement(58208..59215)
                     /locus_tag="VQ847_000338"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3049741.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(59202..60155)
                     /gene="mvaD"
                     /locus_tag="VQ847_000339"
     CDS             complement(59202..60155)
                     /gene="mvaD"
                     /locus_tag="VQ847_000339"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3049742.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(60137..61015)
                     /gene="mvk"
                     /locus_tag="VQ847_000340"
     CDS             complement(60137..61015)
                     /gene="mvk"
                     /locus_tag="VQ847_000340"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3049743.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(61137..61259)
                     /locus_tag="VQ847_000341"
     CDS             complement(61137..61259)
                     /locus_tag="VQ847_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3049744.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        18175 a        14038 c        11500 g        17898 t
ORIGIN      
        1 cagataaagc tgacgcggtt tgaagagatt ttctaagagt ataaaacctt gaagagttgc
       61 cccttcaagg tttttcttat acaaataaac ggacaaaact gtaaagtagc aaaacactac
      121 caagcacgat acggtattta ccaaaaaggg tgaagtcgtg ttttttcaca tagctggtca
      181 agaagcgaat agccaccatg ctgaccgcaa aagctactcc catcgcgacc aagagcaaaa
      241 acaattgccc aaagctcaag agttctccgg ctttcacaaa tttgaaaatc tttaaggcac
      301 tagctccaaa cataacggga atcccaagat agaaggtaaa ttctgtcaca actgaacgac
      361 tggttccatt taacaaacca ccgacaatcg ttgcacctga acggctagtc cctggtaaaa
      421 gagcaagaac ttggaagagt ccgatataga aagcggtcgt ataaggaagc ttgtccaact
      481 ctgttacact tggctcgata gcacgcgctt tattgcgctt ttccaaatag atgaaggcaa
      541 ccccgtagat aatcaacatg agagcaactg aaaccatgtt atggaagtgg gtatcaaacc
      601 aatcatcaaa tttaaagaca ccaagtaaag gcaaagtggc aatcaagacc ttcaaccata
      661 gtctccaagt cttacgaact tcctgtttgt ccttagtcgg tttaaaagga ttgagcttgt
      721 taaaataaat caccataact gctaaaatag caccaagctg aatcacgaca ttaaacatgg
      781 acataaaggc ttcattttga ttttggtatt ggataaactc ctctgctaaa atcaagtgac
      841 ctgtactgga aatcggcaac cattccgtaa ttccttcaac aatcccgaag aagatagatt
      901 ttaaaatttc aataagatac atatatttct ccttatatta tatttaacgc agttagctac
      961 tgccaaagcc caagtggtat acttggaata agccactgtg gattagttca tttcctccaa
     1021 tcgcttgacg atttccgaaa gggtctaaca acagcttttt gtttcaattg gtaatgagtt
     1081 tgataacgca tagacgtttt atctcgtcta aggtaacaag gcaaaaagtt cgtggataac
     1141 caagtagact tgaaatacta tatctggagg tactcccatg ctttatgtgg gcattgatgt
     1201 cgctaaaaat aaacacgatg ttacagcctt gaatgttcga ggaaaactgt tcttaaacca
     1261 ctcacttttt caaataataa agctggtttt gaactcttag atctgtcttt tcgacagctc
     1321 aaccaagact gtctcatcgc tcttaaactt ctttctgacc ccaatcgtga acaatttcaa
     1381 cacgataatc ggcaagtaga actaaaaata ctggctagac atattcatcg tctcaagaaa
     1441 aaacagtctg attggaaagt acaatacact cgttgtcttg atatcatctt tcctgagttg
     1501 gataaaatcg ttggaaagca ttcagaatat acctaccaac tcttgacacg ctaccctaat
     1561 cctcagaaaa ggcttgaggc aagatttgat aagctgatag aaattaagcg attgaccgct
     1621 tctaaaattc aggatatcct ctcagtcgca cctcgttcta tcggaacaac atctcctgct
     1681 cgtgaattcg aaatcatcga aatcatcaaa cattacaaga ggctcattga caaggcggaa
     1741 acatgtgtca atgacttgat ggctgagttc aactcggtca tcacgacggt tactgggatt
     1801 gggggtcgtt taggggcggt cattttagcc gagattcgaa atattcatgc ctttgataat
     1861 cctgctcaat tacaagcttt cgctggactg gattcttcta tttatcagtc aggtcagatt
     1921 gatttagctg gaagaatgat caaacggggt tcccctcatc tgcggtgggc actcatacaa
     1981 gctgccaaag catgcgctcg cttttcacct gcttttaagg cctatcttaa gactaagtta
     2041 gaataaggaa aacattacaa tgtagccatc atccaccttg caaaaaaact tatccgaacc
     2101 ctgttttata tcctaaaaaa gagctgccat ttgacgaaca aaaagtgatg taatttctga
     2161 aattaacaca ggattacctt tgaaaaaatg gactttttca agggcttttt gccgtgctct
     2221 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
     2281 ttcttatagt ttgtctttct tctatcttcc attatatcat actttttcag tctatggtag
     2341 ctctctttaa aaggctccga tactgccgcc acctccgcct ccagagaagc caccgccaga
     2401 acttccactt ccagaagata cggagtaggt acttgctgta tttgcgacac tagcataatg
     2461 gctcatttgc gcgcttgaat gataaaacat actgtgccag ccataagcta catagagatt
     2521 gatatctgga ttttcaactt gaatctgatg aaccttcatc aaatgactaa ccttgtccgc
     2581 atagccaaat aaggttgcat agaccaagag acgattccaa acaacaatac tttccaattc
     2641 agccttatcc agtcgtgcaa tctcacgtaa catattttca aaactggtcc agagatagta
     2701 gacctcagct cccgcttcat ttagaacacc atcacgatta tctagtcgaa gcttccaata
     2761 atagaaaaca gacaaaacta accctagaaa accaagtatt ggcaaaggga ggtaaagata
     2821 gccatgaacg tctaaactgt acaagaacaa accaaatccg ataaataggg gcaagatagt
     2881 caagacaccc atacccactt gcaaagcctt ttccaaacca gttaaaggac gatagtaatc
     2941 tgggagcccc cagaaggaaa ctcgttttct cactccttct tgcatctggt tcaatacctc
     3001 ttcaaaagaa gatttgagtt gaagccctct tgcttgaatc cgtttttcat cagaaacttt
     3061 ggctctacga taaagactat cagatacctt gtaatccgca aacaaattgg aaagagtttc
     3121 ttctttttta cctgaaaaag ctagatttag gcagtctttc tcaaagcttg acaaaccatc
     3181 ttcttttact agcctcaaac caactgcatc tccttctgaa atgatagaga cattcccacg
     3241 gtctatcaca tctagcaagg tagcttgaat aagttgatca aaggtgaatt ttccagctcc
     3301 cttgaccaag ggactcactt cctccaagga ggtcgagtag actgcttctg ataaaaccat
     3361 aggctctaat tccattgggg gttcatagag acgatgattt ttagcatatt tgattgaagg
     3421 agcggtcttt cttctataga taaaatagaa acagatgctc aataacaagg agatggaaag
     3481 gatcgaaggg aagatccaag taagtagttg tttactttga tctttttctt taacgatcga
     3541 atcctctatc ttattaaact cttctaaacg attccctttc aagccctgat ccctagcgct
     3601 agcaaaatca gttcgcggcc agtaggcatg caattcaact ccacgcttag ccggaagatt
     3661 gtctaaacga atagtataat caaggttact cttttcaacc gttctctctc taaaaagttt
     3721 ccctgtatgg aaaaagagtt tctcagcccc cttgtctccc cttacatgaa attcaaactt
     3781 ttcaatagac tctgaactat ctgtcagagg ttgccaattt aattcagcga tatcatcata
     3841 aaggaaaagt aaatttttta agttccagac gaggtcaact tcaactatgt cgccctcctg
     3901 acctggatta tagactctca cagtataacc atccgcttct tctgttactt cgctagtcac
     3961 atctgctagt tctgcaccgt ttttcgcggc ctgaatcttt ggatgagggt caatgtcaaa
     4021 cccgctaggc atcttaccag cacgtccaag tcccacgatt tggcccttaa agtcctcctc
     4081 aaactggtaa actatcttct gtctaaactc tgccgtattg tctgcatgaa tatacaaatc
     4141 cccttgataa gagtttatct tgaaatcaat ggcaaaaaca gagagtggaa gaaggcaaaa
     4201 caagcctaac accagtaaga aaaaagtttt tttcatcaac taagccccct ttttatcttt
     4261 cttatcatta tagcattttt tcgtaagtaa aggcttactt atgttgaaaa attacgcatt
     4321 tttcgataaa ataggagaca gttatttttt aatagatcag aataggagaa atcatgagaa
     4381 aaatatactt atctattttc acaagtctct tgctgatgct aggacttgtc aatgttgctc
     4441 aagccgatga atatttacgc atcggtatgg aagcagcata tgctcccttt aactggaccc
     4501 aggatgatga tagcaacgga gctgtcaaaa tcgatgggac caatcagtat gccaacggat
     4561 acgatgttca aatcgccaag aaaatcgcta aggacttagg taaagaacct ttggttgtta
     4621 aaaccaagtg ggaaggtcta gtccctgccc ttacttctgg taagattgac atgattatcg
     4681 caggtatgag tccaactgca gaacgcaaac aagaaattgc cttttcgagc agttactata
     4741 ctagcgaacc agttttgctt gtcaaaaaag attctgccta cgcaagtgct aaatctttgg
     4801 atgactttaa cggtgcaaaa atcacttctc aacaaggggt ctacctttat aacttgattg
     4861 cacaaatcct aggtgctaaa aaagaaacag ccatgggaga cttcgctcaa atgcgacaag
     4921 ctcttgaggc tggtgtcatt gatgcttatg tttctgaacg tccagaagca ctgactgctg
     4981 aagctgcgaa ctctaagttc aagatgattc aagtagaacc tggtttcaaa actggggaag
     5041 aagatacagc tatcgctatc gggcttcgta aaaatgacaa tcgtattagc caaatcaatg
     5101 ccagcattga aaccatttca aaagatgacc aagttgcctt gatggatcgt atgatcaagg
     5161 aacaacctgc cgaagctaca acaactgaag agactagcag tagtttcttt agccaagttg
     5221 ctaaaattct ttctgaaaac tggcaacaac tcttgcgtgg tgctggtatc actcttttaa
     5281 tctctatcgt cggaaccatc ataggtctca ttattggact tgccattggt gtcttccgta
     5341 ctgctcctct ctctgaaaac aaagtcattt acggcctaca aaaactagtc ggctgggttc
     5401 tcaatgtcta cattgaaatt ttccgtggta cgccaatgat tgttcaatcg atggttatct
     5461 actatggaac tgcccaagct ttcgggatca accttgaccg tacactggct gctatcttca
     5521 tcgtttcaat caataccggt gcctacatga ctgaaatcgt ccgtggtggt atcctagcag
     5581 ttgacaaggg acaatttgaa gctgcgactg ctcttggtat gacccataac cagaccatgc
     5641 gtaagattgt cctacctcag gtagtccgta acatcctacc tgcaactggt aatgaatttg
     5701 tcatcaatat caaagataca tctgtattga acgttatctc tgttgtcgaa ctttatttct
     5761 caggaaatac cgtggcaaca caaacctatc aatacttcca gacatttaca atcatcgccg
     5821 tgatttactt tgtcctcacc ttcaccgtaa cacgtatcct acgctttatc gagcgcagaa
     5881 tggacatgga tacctacact acaggtgcta accaaatgca aacggaggat ttgaaataat
     5941 gacacaagca atccttgaaa ttaaacacct caaaaaatcc tatggacaaa acgaagtgct
     6001 aaaagacatt tcactcactg tccacaaggg agaggtcatc tctatcatcg gaagctctgg
     6061 aagcggaaaa tcgaccttcc tacgctccat taacctactt gaaacaccaa ctgatggaca
     6121 aatcctttat catggacaaa acgtcctcga aaaaggctat gacctcacgc aataccgtga
     6181 aaagttgggg atggttttcc aatcctttaa cctctttgaa aatctcaatg ttcttgaaaa
     6241 cacaatcgtc gctcagacaa ctgtcctaaa acgcgaacgc acagaagctg aaaagattgc
     6301 caaagaaaac ctggaaaagg tcggcatggg agaacgctac tggcaagcca aaccaaaaca
     6361 actctcaggt ggtcaaaaac aacgtgtggc catcgctcgt gccctctcca tgaatccgga
     6421 cgctattctc tttgatgaac caacatcagc tctcgatcca gaaatggttg gagaagtcct
     6481 caaaatcatg caggacctgg ctcaggaagg cttgaccatg attgtcgtaa cccatgaaat
     6541 ggaatttgcc cgtgatgtct ctcaccgtgt tatctttatg gataagggcg tgatcgctga
     6601 agaaggtaaa ccagaagacc tcttcaccaa tcctaaagaa gaccgaacaa aagagttcct
     6661 tcaacgctat ctcaaataaa aagaaaaggc tgcatcaacc gtgcagtctt tttgctgtcc
     6721 tcaaaatgaa aaggcagatt ctctatctct actacttgaa ggtcaagaat ccgccgttat
     6781 ccaaagatta atcttcaaat ttttcataat ttttttcata gaaatcaatt aggcctaggg
     6841 ctgtttcaaa tgaaatattt tttacttttg cacgaccctg cgccagagca atgatagaca
     6901 tttcacgcgc attcgtttct ttagagatac ggtagcctgt gattttctta tcacgaaccc
     6961 agccaacaac tgattctact ttttcaaagt ttgacttagc catgtttttc tcctattttc
     7021 ttctttataa tatttaattg tatacgtttt tactactttt gtcaataaaa aaaacatata
     7081 ttcaacgaaa ataattagtt cagaattttc ttacttcctt tttaaatccg ataatatata
     7141 ggttttgcta gcctctacac cataaatatt tgctaataaa aatactgtat tattaccctc
     7201 ttaaggtgcg aaattattca agttcttaaa aaatgcttct ctatttccgt aagatagctt
     7261 atttcttcga tttaagaact gaagatgata gttctaacct ttagaaatcc aagccttcac
     7321 tagctcaaaa actcctatct ttcttcctca ataaatcatc tgagagatag gtattcctta
     7381 tgtccttaaa attcatcact cctttggata ttgaggtgct agcctagaag cagacacccg
     7441 attatctaaa ccatccttaa tagagatgac aagacagata agctcagtta attacttata
     7501 tatcttttta atatggtata tttgtcaaca aaaagaaatc aaatcatacc ttatactcaa
     7561 tgaaaatcaa agagcaaact aggaagctag ccgcaagttg ctcaaaacac tgttttgagg
     7621 ttgcagatag agctaacgtg gtttgaagag attttcgaag agtattaaag acagtgtgac
     7681 tatgcttgtc aatagatagg aaatcaaaat gaaggatgga aatctgagcc aaacatcata
     7741 agtgctataa tgaacagaag taagaattgc acgataagtt ttctaaaacc ataggaatcg
     7801 tcccctttct tcatcttcat tatagcacat atacatcagt tgtacaaata atatgatatt
     7861 tttttattag tcctcagaca agcatattat aaagcgtttc attaccattt aagttaatat
     7921 aagctggatc aaaaccttcc attctacgaa tcaaacctgc ataatcatgc ttatctgcta
     7981 aagcgatccc aattaatact gggcctgttc ccttgctagc tcgtttgata tactcaaaac
     8041 gtgtgatatc atcatttggc cccaggatat catttacaaa ctcacgcaaa gctcctggac
     8101 gttgtgggaa attgaccaca aagtaatgtt tgataccatc ataaatcaag gcacgctctt
     8161 ccatttctgg catacggttg atatcattat ttcctccaga aatgatacaa caaatggttt
     8221 tccccttaat atattcagct aaaacctcta aagaggcgat actagccgct ccagcaggtt
     8281 ctgcgactat cccttgctta gagtaaaggt caatcaaggt ttcagaaatc aatccctcat
     8341 cgacacctac caaagtttta atatgttgac gagttgcttc ataggtcaac tgacctacct
     8401 tttgcacagc aatcccatca gcaaatttat caatttcctt gagtttgact ggacctccag
     8461 cctcaaaggc agctttcatg gaacgcgctc cattcgcctc tactccgata acctcaatct
     8521 ctggacttgt ttccttgata taggtagaaa ccccggcaat gagaccgcca ccaccaacag
     8581 gaaccaagac agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa atctcataag
     8641 caactgttcc ttgacctgct tgaacatgag catcatcaaa aggatcaata aaggtacgat
     8701 tttcagagac tgtaaattct tgagctgctt tggctgaggc atcaaaggta tctccaacta
     8761 gtttaatagt tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg
     8821 tagtaatggg cataaagata gtagcaggaa ttttcatttc attacaagta taggctactc
     8881 cctgcgcatg atttcccgca gaagcgcaga ctaccccacg ttcacgttct tccttgctga
     8941 gctgggaaat ggcataatag gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt
     9001 cttttttcaa ataaatctta gcaccatact tctccgataa ataatgatcg taatccagtg
     9061 gagtattcac aaccacaccg ttcaagacct tgtgagcctt gattatatct tttgaactta
     9121 acatataaaa cctctttttc tataaaaaac agtcactaat gactgttttt tagttattca
     9181 tctccgaaaa cttcagtaac actttcatgg tatttatgag ccatacgaat cgaaaactct
     9241 ttaggaagtt cataacgatt tgtggaaatc caatcatata accattctac caaactttct
     9301 tcactatcat tacgatggaa gataaaatag tttaaaattt ctttatattc tacatcattc
     9361 aaatccaacg tgtctacaaa ttgactacga ggaacaaaat tagaatctaa ttttcttagt
     9421 tgatctgtca attctcccaa ttgtaaatcc aactgaaaaa atagtttttg cagttgccta
     9481 tcagtttcat cacatcctgt cttgatagaa aacaaattgg taatattcat atgatttcaa
     9541 cccctaaata agtacatcta atatcccacg aatagctgaa gctaaagttt tcgcagtcca
     9601 gtcatttaaa cccgattctt tcaatccaga tgcaataatt tgctctattt gatataaatc
     9661 gccatctatc gtctcattta ttctgcgaag aggaccttca atataggata aagcttctcc
     9721 gaatctaaca gctgatttag gtcctaatga tttaccaact atatttgtta atgtttttta
     9781 tttctcaaaa tccatttcgc tatataacga gcagatttag tcgcatcagc tctctcaaac
     9841 ggagaatgaa tttcaagacc ttcttctcta gctatttgtg ccaatttgaa gaattgttca
     9901 aaggtcatat gcaacctacc atcttcaaaa ttagcatcat cataaatgtt aattacagca
     9961 ttttcatcat acgaccaatc tgctttattt tggtctgcta gcactattac cgacggtgta
    10021 attacattat acaactagaa ccaataataa cgatgcaatt tttctcataa tctttttcat
    10081 aaaatcatct ccagcgctat atatttctaa ttagttatag attttgaatg catcatcgtc
    10141 gtttttacca acgaatggca ttgctttacg caattctgca ccaacttttt caatttcaag
    10201 gttagctgct tgttcacggt aagcagtcaa ttttggacgt ccagctttat agtcatttac
    10261 aaagtcattt gcaaacttac cattttggat gtctgccaag acagccttca tattttcttt
    10321 aacttgttca gtgattacac gtggacctga tacatagtca ccgtattcag cagtgtttga
    10381 aatagactga cgcattttct tgaatccacc ttcgtagatc aagtcaacga tcaatttcat
    10441 ttcgtgaaga acttcaaagt aagccaattc tggagcgtaa cctgcttctg tcaagacttc
    10501 gaaacctgct tcgataaggg cagtcaaacc accacaaagt acagcttgtt caccaaacaa
    10561 atcttcttca gtttcttctt tgtaagttgt ttcaagaaga cctacacgag ccgctccaac
    10621 acctttacac cagtccatag caatgttttt agcatttcct gttgcatctt ggtatactgc
    10681 ataaagagct ggaacaccaa atccttcttc gtaagtacga cgtaccaagt gtcctggtcc
    10741 tttaggagca cacatgaaga catctacatc cgcaggaact ttgataaatt caaagtggat
    10801 gttgaaacca tgggcaaatc caactgcgtt tccagcttcc aagtttggag cgatttctgc
    10861 ttcgtacaat tcttgttgaa tttcgtctgg cgccaagatc atgataacat cagccaactt
    10921 agtagcttct gctactgtgt aagtatcaaa tccatcttct tttgctttat caaaagattt
    10981 acctggacgt acaccgataa taacgtcacg accggaatca cgcaagtttt gagcatgcgc
    11041 atgcccttgt gaaccataac cgataacggc gattttttta ccgtcaagtg ctgctacttt
    11101 aacatctttt tcatattcca tttgaactgt catagctttt ctctcttttc tattatttat
    11161 tgccttttag gctggtttaa taaatttaag ttggattttt aatcgcgggt aaatccagtt
    11221 gcacccgttc gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa tagggcttcg
    11281 ctcttttctg catttcccgt catctgaatg gtaatcgagc ttggcgctac gtctaccact
    11341 gttgcacgga aaggttgaat aatcgctaaa atctcagctc tcttctcagc tggcgctgac
    11401 atcttaacca aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga
    11461 atcacatcaa tctgacgatt gagctgtttg atgatttgct ccacttcatc atgagaagca
    11521 acatcaataa taatagtgat acgcgataca ttcggatctt ctgttgctcc aacagagatg
    11581 ctttcaatat taacctgacg acgagatagg acacctgtaa agcgattgag tactcctgaa
    11641 cgattttgta gttttgctgt taacattcta cgcatggaac ttcaccccca acatctcatg
    11701 attactctta ccagccggta ccattggtaa cacctgttcc ttacgagaaa tatctacctc
    11761 aattagcata ggaacatcct cagtgatgac ttcaaggtct tgagccaagg tctcaggatt
    11821 gtcaaactta tagtttttaa taccataagc ctgcgccatc aattggaaat caggaagggt
    11881 atcaaagacc gactctgatg ttctgccttc atagaaggat tcctgccact ggcgaaccat
    11941 tccaagtgaa tgattgttca gcataaccac cttgattggc accttgtaaa tattcaaaat
    12001 agccaactcc tggttggtca tttggaaacc accatcccca acaaacaaga ctacttcctt
    12061 atctgggtta gcaattttag caccgattgc tgctggaatt ccaaagccca ttgttcccaa
    12121 accacctgaa gtcactaact gacgctcatt ttggtaggga taatactgag ctgtccacat
    12181 ttggtgttga ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt caccaattcg
    12241 ttcaataact gcttgcggtt gaaccacacg ctctttcttg tcataagaac gaacacgatt
    12301 cttgtcttta gtgactttct caatccactt ttcagtattg ttgtgaactg ttggttctgc
    12361 tagcaacatt tgcaaggcct tcttagcatc tccaactaca ggaatgtctg cactgataat
    12421 cttgccaatc tcagctgggt caatatcaat gtgggcaacc ttagcattct tagcgaaagt
    12481 cttaggattc cccgtcaaac ggtcatcgaa acgagaacca atactaatca taaagtccgc
    12541 ttccgtcatg gcaatatttg ctgcgaatga cccgtgcatg cctcccattc caagaaagag
    12601 tgggtgactc gttgcaatcg ttccttgtcc caaaagactg gttaccactg gaatttgata
    12661 gcgttctgca aattcattta gttccgtagc agcctcagca taactaattc caccaccagc
    12721 taacaagact ggctttttag ccttggacaa ttgcttcaag attttcttga tttgcatatc
    12781 attcggctca agagtcggct gataacttgg taaattcact tctggtgaat aaatgaagtc
    12841 tgtttctaaa gcagatatgt cttttggtag gtcaattaca actggccctg gacggcctgt
    12901 agttgcgata tggacagctt ccgtaatgat acgcggaata tcagctgtct cacgaacttg
    12961 gtaattgtac ttagtgattg gcatggtaat tcccacgatg tctgcctcct gaaaggcatc
    13021 cttcccaatc cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct
    13081 catggcatcc gcaatccctg taatggcatt tgttgctcct ggtccactag tgacgacggc
    13141 aacacccaac tttccagttg atttggcata accttcagct tcatgcaaac aaccttgctc
    13201 atggcgccct agaatgtggc gaatgccttt aaaattatat atcgcatcat aaaaaggcaa
    13261 aaccgcacca ccaggataac caaagatggt atcaactcct aaatcacgaa gtgtttccaa
    13321 aactaggtcc gaccccgtct taggagattc taaactgatt ttctccatta ttcccctttc
    13381 tttcctctta aaaataactt gttactatca taccattttt tcaaaatttt tcaagataaa
    13441 agaagaaatt ttctgaattt tctattttaa cgtttattta tgaatgttat ttttgttttt
    13501 attaaaaaga taccgatttc atttactaaa aaagaaaaaa gaactgattt ctcagtcctt
    13561 cattaatctt attccacact aaataggtat gggtaaacag gttgttgacc ttggtgaatc
    13621 tcgacttcaa cgtcttcgaa ttcttctacg atttcttgag cgatttcatt ggcaagttct
    13681 tcgcttccgt cttcaccgac atagaaggtt acgatttcac tgtcttcatc caacatatgt
    13741 ttcaaggttt cagtcaatgt ttggtgcata tcagggtttg acacaagaat ttttccatcc
    13801 accataccta gattatcgtt ttcatggatt tctaagccat cgatcgttgt atcacgcacg
    13861 gctgttgtga cgcttccgct aacaacatcg ctaagagcag ctgtcatacg ctcttggttt
    13921 tcttcaatgg acttgcttgg atcaaaggca agaagacttg tcataccttg aggaagagtg
    13981 cgagcctcta ccactactgc tggttgctcc aaaacttctg ccgcagattg agctgccatg
    14041 aagatgttct tgttgtttgg caagaagatg atgttacggg cattgacctg ttcaacagcc
    14101 ttgataaagt cttctgttga agggttcatg gtttgaccgc cttcgataac ataatccacg
    14161 ccttgagaac agaagatatc tgctagacct ttaccagcca ccacagcaat caaagcatac
    14221 tctttttctt cagccgactt gataacttga gtagcttctt tctcaacctg tgcttcgtgt
    14281 tggttacgca tattgtcaac ttttaccttg accaagctac catatttgag accttcttgc
    14341 ataacaagtc ctggatcttc tgtatgaaca tggactttga caatttcatc atcgttaaca
    14401 acgaggagag aatccccaag ctcatccaag tagttacgga attcatcgta gtcaaaatct
    14461 ttagcatagg ttggaccttg cttaagagct accatgattt cagtacagta accaaacgtg
    14521 atgtcctcag tcgctacgtg accagctaca gacttatgat gctctacatt gatcatctca
    14581 ctcatgttgg caggagtcgc tacaaagtcc tcagatgcaa tatattcgcc agtaagggct
    14641 gaaaggaaac cttcgtagat gaagaccaat ccttgaccac ctgagtccac aacgccaact
    14701 tctttcaata ctggaagcat gtctggtgtt ttagctagag ctgttttagc accttccaag
    14761 gctgcgcgca tgacttcaac agcgtcatct gtttgctcag cttttttctt agcaccgata
    14821 gcagctccac gagaaactgt taaaatcgtt ccttcaacag gtttcatcac tgccttatag
    14881 gcaacttcca cacctgattg gaaggccaga gccaagtctt gacctgttaa ctcgtcttta
    14941 tccttgatag cttgggaaaa tccacggaaa agctgagacg taatcactcc tgagttccca
    15001 cgcgcaccca tcaaaagccc tttggcaaga atgctcgcta cttctccaac tgtagaagct
    15061 ggcttgtctg caacttcttt agcaccattt tcaatggtca ttcccatatt tgtcccagta
    15121 tctccatctg ggactggaaa gacgtttaat gaattgacat attcagcttg cttattcaag
    15181 cgagttgatg cagcctgcac catttcttga aataagctag tagtaatttt tgacacggtt
    15241 attctcctac aactttgata ttttgaatgt agacatttac agtctgagca gtaattccaa
    15301 gctggttttc caagctaaag gcaacacgct cttgaatgtt ttttgacact tcactaatct
    15361 ttgttccgta gcttaacacg gtatatacat caactgcaat actgccatct tcggctgcct
    15421 ttacgacgac acctttagaa taattttcct tacctagcag ggcttggaaa ttatctttga
    15481 gggcattttt actagccata ccgaccacac caaaaatctc agttgctgct ccacctacga
    15541 cggttgcaat cacttcatct gttagttcga tttgaccatc ttttgtatta atttttacag
    15601 tcatcctttt tacctcaact agttgatact ctattttatc atatttcagc ccaagtgtaa
    15661 aagcagaatg atgtatcagc ggatatttac tctatttttc aaacgatgtt atacccacaa
    15721 taaaagaaaa aagaccctaa ggtctccttt gcttttatta ttaaacgcgt tcaactttac
    15781 ctgatttcaa agcacgagct gaagcccaaa cttttttagg tttaccatcg ataagaacag
    15841 taactttttg aaggtttggt tttacggcac gttttgtttg gttcatcgcg tgtgaacggt
    15901 tgtttcctga tacagtctta cgacctgtaa agtaacatac tttagccatt gtgttttcct
    15961 cctattagat ctaatatagc ggatgtgcta gcaccacata ccgtactatg ttatcacact
    16021 ttcttgtttt ttgcaaggga attggaagat tttttatttg tgtcttaaat caggtcttgc
    16081 gtgacatttt ctgctctcca catgccattg ttgattaaca gaacaccaga attaaaatta
    16141 tgtgtataaa aatcatctct aactgcagct aagggtatag ccgtcaagtc caaatcccac
    16201 agctcatcta tcgattttct tacaacaata tctgaatcca aatacagtac acgagactcg
    16261 cttacatact ttggaataaa atacctaaaa aaagccgcat atgaaagtcc ctcaaagggg
    16321 agacgataac ctttcagaat actactgtca atctgaacat tcacaatctc actattcaaa
    16381 gtctctagtc ttttttccat caattggaac cattctcgcg gaaggtcatc attaaaaaca
    16441 taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc aactttatcc
    16501 atataagcat tatctgcacc taagacaatc gcttttttct cttctttcac tctttatctt
    16561 atttcttttt attcccatca tattattccc atcatatgtt tctacgtaac cattattttc
    16621 gcctattcgt tcgtaaaacc ataccagtgg agattttaga tgaagtccca ttacggttta
    16681 cattttttac attacgacac ggagttttac aaatcgattt catttgccaa acgtagttag
    16741 tgaggcagtt agctagttcg ccaaatagcg actagcgtcc aacaatttgg aactttagtt
    16801 ccaattgttg gtactgagtc acatcttctc ctctaactct acgtctggat acttgtccgc
    16861 aaaccagcgg agggcaaagt cattttcaaa gagaaagact ggttggtcaa aacggtcttt
    16921 ggctaagata ttgcgacttg acgacatccg ttcatccaag tcctcaggct tgatccaacg
    16981 aacggtcttt ttacccattg ggttcataac tacttccgca ttgtactcgc tttccatgcg
    17041 gtgtttaaag acttcaaact ggagttgacc tacagcgcct agcatgtact cacctgtttg
    17101 gtaattctta taaagctgaa cggctccttc ttgcaccaat tgctcaatcc ccttgtggaa
    17161 ggatttttgc ttcataacat tcttagcaga aactttcatg aaaatttcag gagtaaaggt
    17221 tggcagtggt tcaaattcaa acttgttttt tccaaccgtc aaggtatccc caacctgata
    17281 agtaccggta tcgtaaaccc cgataatatc acctgccacg gcattggtca cattctcacg
    17341 actctccgcc ataaactggg taacattaga tagtttggca cccttaccag tacgagggag
    17401 attgacactc atgccacgct caaattcgcc tgatacgata cggacaaagg caatacggtc
    17461 acggtgacga ggatccatgt tggcttggat tttaaagaca aagcctgaga aatccttgtc
    17521 ataaggatcc acaatttcac cgtctgtttt cttgtgacca tgtggttctg gagcaaactt
    17581 gaggaagatt tcaaggaagg tctgcacacc aaagtttgtc agggctgaac cgaaaaagac
    17641 aggcgtcaat tctccagcca gaatagcttc ctctgaaaac tcattcccag cttcatttaa
    17701 aagctcaatg tcatccttga cttgctcgta gaaaggattg ctaccaaaaa gtttgtctcc
    17761 atcttctagg ctagcaaaac gctcatcccc tttgtaaagc tctaaacgtt ggttatagag
    17821 gtcatacaag ccctcaaagg ctttccccat cccgataggc cagttcatag ggtagctagc
    17881 aatgcccaag atttcttcca attcttgcaa gagatccaaa ggctcacgac cgtcacgatc
    17941 caacttgttc ataaaggtaa agactggaat gccacgatgt ttcacaacct caaacaattt
    18001 ctttgtttga gcctcgatcc ccttggcaga gtccacgacc atgaccgcag catccaccgc
    18061 catcaaggta cgataggtat cttctgagaa gtcctcgtgc cctggcgtgt ctaagatatt
    18121 cacgcgcttg ccgtcgtagt caaattgcat aacagatgaa gtaacagaaa tcccacgttg
    18181 cttctcgata tccatccagt cagatttagc aaaagtccct gttttcttcc cttttaccgt
    18241 accagcatca cgaatctcac ccccaaagta gagtaactgc tcagtgatgg ttgttttccc
    18301 cgcgtccggg tgggagataa tggcaaaggt acgacgtttc ttaatttctt cttgaatatt
    18361 cataagttct ctttccttga ttctctattt ttcttgtttc aatagctgag aatgattttt
    18421 acattggatt ttaccattcc tttcgacact ccattatatc ggattttagc atttttttca
    18481 atttctattt cttttcactt ccccctccct tatttatagg aaaatatggt aaaatagaac
    18541 agactaaaaa tcatcatttc acgaaaggat gcaagatgaa aattacgcaa gaagaggtaa
    18601 cacacgttgc caatctttca aaattaagat tctctgaaaa agaaactgct gcctttgcga
    18661 ccaccttgtc taagattgtt gacatggttg aattgctggg cgaagttgac acaactggtg
    18721 tcgcacctac tacgactatg gctgaccgca agactgtact ccgccctgat gtggccgaag
    18781 aaggaacaga ccgtgatcgc ttgtttaaaa acgtacctga acaagacaac tactatatca
    18841 aggtgccagc tatcctagac gatggaggag atgcctaatg acttttaaca ataaaactat
    18901 tgaagagttg cacaatctcc ttgtctctaa ggaaatttct gcaacagaat tgacccaagc
    18961 aacacttgaa aatatcaagt ctcgtgagga agccctcaat tcatttgtca ccatcgctga
    19021 ggagcaagct cttgttcaag ctaaagccat tgatgaagct ggaattgatg ctgacaatgt
    19081 cctttcagga attccacttg ctgttaagga taacatctct acagacggta ttctcacaac
    19141 tgctgcctca aaaatgctct acaactatga gccaatcttt gatgcgacag ctgttgccaa
    19201 tgcaaaaacc aaaggcatga ttgtcgttgg aaagaccaac atggacgaat ttgctatggg
    19261 tggttcaggt gaaacttcac actacggagc aactaaaaac gcttgggacc acagcaaggt
    19321 tcctggtggg tcatcaagtg gttctgccgc agctgtagcc tcaggacaag ttcgcttgtc
    19381 acttggttct gatactggtg gttccatccg ccaacctgct gccttcaacg gaatcgttgg
    19441 tctcaaacca acctacggaa cagtttcacg tttcggtctc attgcctttg gtagctcatt
    19501 agaccagatt ggaccttttg ctcctactgt taaggaaaat gccctcttgc tcaacgctat
    19561 tgccagcgaa gatgctaaag actctacttc tgctcctgtc cgcatcgccg actttacttc
    19621 aaaaatcggc caagacatca agggtatgaa aatcgctttg cctaaggaat acctcggtga
    19681 aggaattaac ccagaggtta aggaaaccat tctaaatgcc gctaaacact ttgaaaaatt
    19741 gggtgctatt gtcgaagaag tcagccttcc tcactctaaa tacggagttg ccgtatacta
    19801 catcatcgct tcatcagaag cttcatcaaa cttgcaacgc ttcgacggta tccgttacgg
    19861 ctatcgcgca gaagatgcaa ccaaccttga tgaaatctat gtaaacagcc gaagccaagg
    19921 ttttggtgaa gaagtgaagc gccgtatcat gctgggtact ttcagtcttt catcaggtta
    19981 ctacgatgcc tactataaga aggctggaca ggtccgtaca cttatcattc aagatttcga
    20041 aaaagtcttc gcggattacg atttgatttt gggtccaact gctccaagtg ttgcctatga
    20101 cttggattct ctcaaccatg acccagttgc catgtactta gccgacctat tgaccatacc
    20161 tgtaaacttg gcaggactgc ctggaatttc gattcctgct ggattctctc aaggtctacc
    20221 tgtcggactc caattgattg gtcccaagta ctctgaggaa accatttacc aagctgctgc
    20281 tgcttttgaa gcaacaacag actaccacaa acaacaaccc gtgatttttg gaggtgacaa
    20341 ctaatgaact ttgaaacagt catcggactt gaagtccacg tagagctcaa caccaattca
    20401 aaaatcttct cacctacttc tgcccacttt ggaaatgacc aaaatgccaa cactaacgtg
    20461 attgactggt ctttcccagg agttctacca gttctcaata aaggggttgt tgatgccggt
    20521 atcaaggctg ctcttgccct caacatggac atccacaaaa agatgcactt tgaccgcaag
    20581 aactacttct atcctgataa ccccaaagcc taccaaattt ctcaatttga tgaaccaatc
    20641 ggatataatg gctggattga agtcaaacta gaagacggta cgaccaagaa aatcggtatc
    20701 gaacgtgccc acctagagga agacgctggt aaaaacaccc atggtacaga tggctactct
    20761 tatgttgacc tcaaccgcca aggggttccc ttgattgaga ttgtatctga ggcagatatg
    20821 cgttctcctg aagaagccta tgcttatctg acagccctca aggaagttat ccagtacgct
    20881 ggcatttctg acgttaagat ggaggaaggt tcgatgcgtg tggatgccaa catctccctt
    20941 cgtccttatg gtcaagagaa attcggtacc aagactgaat tgaagaacct caactccttc
    21001 tcaaacgttc gcaaggggct tgaatacgaa atccaacgtc aagctgaaat acttcgctca
    21061 ggtggtcaaa ttcgccaaga aacacgccgt tacgatgaag ctaacaaaac aaccatcctc
    21121 atgcgtgtca aggaaggggc tgcagactac cgctacttcc cagaaccaga cctacccctc
    21181 tttgaaattt ctgacgagtg gattgaggaa atgcggactg agttgccaga gtttccaaaa
    21241 gaacgtcgtg cgcgttatgt atctgacctt ggtttatcag actacgatgc taatcagttg
    21301 actgctaata aagtcacttc tgacttcttt gaaaaagctg ttgccctagg tggtgatgcc
    21361 aaacaagtct ctaactggct ccaaggggaa gtcgctcagt tcttgaatgc tgaaggtaaa
    21421 acactggaac aaatcgaatt gacaccagaa aacttggttg aaatgattac catcatcgaa
    21481 gacggtacta tttcatctaa gattgccaag aaagtctttg tccatctagc taaaaatggc
    21541 ggtggcgcgc gtgaatacgt ggaaaaagca ggtatggttc aaatttcaga tccagctatc
    21601 ttgatcccaa tcatccacca agtctttgcc gataacgaag ctgctgttgc cgacttcaag
    21661 tcaggcaaac gtaacgccga caaggccttt acaggattcc ttatgaaggc aaccaaaggc
    21721 caagccaacc cacaagttgc ccttaaacta cttgcacagg aattggcgaa gttgaaagaa
    21781 aactagacag aacaaaacca gccctaaggt tggttttttc ttgacaaata gaaagaaaac
    21841 gtttacaata ttgcgtgtaa agtttccaaa caagaaaact aaaaatcgca acaataagga
    21901 gttatttata tggctacaat gaaggcagct cgctggcatg cagcgaaaga tgttcgtatt
    21961 caagaaatag aagttcctga agtacttccg caccaagtaa aagttgcagt taagttcaca
    22021 ggaatttgtg gtactgacct ccatgaattt ttagatggac ctatctttat cccaacagat
    22081 gagcacgtct attctggtca aaaagcaccg gtaacactgg gacatgaatt ttctggtgaa
    22141 atcatagaag tcggaagcga tgttacccgt gttaaagttg gtgatcgtgt tgctgtggaa
    22201 ccaattctag ctaaaaataa cttagttggt gattataatt tggatccaaa ccttaatttt
    22261 gtcggtttgg ctgcagacgg tggatttgcc aaatattgtg ttttagacgg tgacttagta
    22321 catgtcattc cagatagctt gagctatgaa caagctgctc ttactgaacc cgctgctgtt
    22381 gcagtctatg ctgttcgtca atcttctttg aaggctggcg atacagctgt tgtctttggt
    22441 ttaggcccga ttggtctatt aattgtagaa gctcttcgtg cagctggtgc ttctaagatt
    22501 tatgctgttg aactatcacc tgaacgtcaa gcaaaagctg aagagttagg agctatcgtt
    22561 gtccgtccgg aagaaggtga aacagctgtt gaagctattc atcgtttaac aaacggtggt
    22621 gtagatgttt cttatgaagt aacgggtgtg ccagtagttt taggacaagc cttagctgcc
    22681 gtacataaag caggtgagtg catggtggtc tctatctggg aacgagaagc aaatattaat
    22741 ccgaatgaat ttgcaatcca agaaaagaca ctaaaaggaa tcatcgctta tcgtcatatc
    22801 ttccctaaag tattagaatt gatggaacaa ggctacttct ctgctgaaaa attagttact
    22861 aagaaaatta aattggaaaa tatcgtcgaa gaaggcttta tcgaattaac tcaagataag
    22921 tcacaaatta aaattttggt agaaccagaa taaaaaatca atctttttaa gacaatacta
    22981 acaggtcgga gtaaacttac ttcggccttt tgaaatataa tactcttcga aaatctcttc
    23041 aaaccacgtc agcgtcacat taccgtatat atggttactg acttcgtcag ttctatccac
    23101 aacctcaaaa cagtgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttc
    23161 cattgagtat gagaagaaat atagtggata ctctttaaca ttaaccactc cacctgacta
    23221 gccaatattc tttttcgctc ctaccaactc ccaataacta ttttggcttt atttccagag
    23281 tattttatgg taaaatgaag agtaataata tttgttaaag aggtaaaaac atgattgaag
    23341 caagtaaatt aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt
    23401 tggaagctag tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg
    23461 atgtccgtac tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag
    23521 ctattatcga gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca
    23581 tgaatacaga aacttacgac cagtacgaaa tccctgtagt caatgttgaa aacgaattgc
    23641 tttacatcct tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg
    23701 tcaccgttcc tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg
    23761 ctactgttac aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc
    23821 cagacttcat cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt
    23881 ctcgtgccta atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa
    23941 tcgttatcgc cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg
    24001 gtgttcactc tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc
    24061 gtggcattta tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg
    24121 agtacggagt aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg
    24181 tccgtaatat ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc
    24241 cagataaaac accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact
    24301 agtccactat tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc
    24361 cttgagttcg gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa
    24421 gatacggatg tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa
    24481 aaggaagaac tagataagca aatcactcag catttaaaag caggttggac cattgaacgc
    24541 ttaacgctcg tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac
    24601 actcctcagc tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa
    24661 aaatctgccc gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa
    24721 gaaaaagtgt ttgatagata tcaaacactt ttttctttgc ctcccactat ctaaaaaaat
    24781 gataatagat ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa
    24841 aaaaactatg gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa
    24901 aaaagaaacc aatcagacta taatataata aactaattgg atctctgtga gatagtatca
    24961 aatggctaat cccaaagatg atagcagata ggataacatc caaatagtac ttggactagg
    25021 gaaagaaggt attcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga
    25081 ttacaggcag gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaaaaa
    25141 gcacggtaaa atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc
    25201 aaaaattacc gagaatctga taaaccacat aagttgcaaa taagtagaag acaaatgacc
    25261 agttccagct ctttttctca aagataaaga gcatcttttt cttttttaac ctccaaatta
    25321 atagaaggaa acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta
    25381 accctaaaat gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa
    25441 taataagcaa aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt
    25501 gaaagattac cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc
    25561 ttgcctcata tagggagcaa attctctata atataaccat ctactatatc catcttccca
    25621 aacagcaaga ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt
    25681 tgtacctgtc attgcaagta ccttcttaaa atagattgtt gtaggctcac atttatagta
    25741 tatttctttt tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa
    25801 ttacattttt ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt
    25861 ctaaatcgtt gatagcgttc ttccagcaac tcttctagcg gtttttgtga aagtctagcc
    25921 agctctgttt ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt
    25981 tcagaaatca ccttatctac cacgtccatt tctaacagtt catgcgaagt gattttcatc
    26041 agttctgctg cttccatagc gcgagtaccg tccttccata aaatggaagc aaagccttct
    26101 ggactgagaa tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga
    26161 gccagagccc cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg
    26221 tcactcattt ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttccgctccg
    26281 acaccaggat aagcacctgc tgtattgata aaggtcacaa ctggacggcc aaatttctca
    26341 gcctgtttca tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc
    26401 cgtttgaggt tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttga
    26461 tctccaagcc aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca
    26521 tgtaattgga taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc
    26581 tgctcacgcg cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc
    26641 tgactaggct agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc
    26701 catgttctaa taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat
    26761 tttcaatcac acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat
    26821 cgccttccat agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca
    26881 ggtaaaagag accaacattt gaatggcgtt taaccgccgc agagatctta gccatctgca
    26941 tgagactcat gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg
    27001 gcaatttttc gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac
    27061 ccatagaagc catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa
    27121 taagagcagt tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca
    27181 gtttcttttg gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt
    27241 ctttgaaggt tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg
    27301 tatagctaca gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct
    27361 tacagcctgg acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt
    27421 ccctaaccga acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca
    27481 ttgattcccc ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag
    27541 gtaagaaggt ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg
    27601 aaatgaggtc aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga
    27661 gggcacgttg cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg
    27721 caatcatact atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc
    27781 gcaaaccaac tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa
    27841 agttaaaggc tgggttttct gcattgatac gacactcgat ggcatgacca cgtaggacaa
    27901 tatcttcttg cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga
    27961 tatcaacacc tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct
    28021 ccatgaaata gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct
    28081 catagccaac aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt
    28141 ttccgattgc aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac
    28201 aatcccgttc acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa
    28261 tgtgccgagc tggatagata acccgttcta tgtacatggc accattgcca taattggcct
    28321 tggcctcact agaggcagtt tcaaaggcag aaacgaggtc atctggtttt tcaaccttac
    28381 gaatcccttt accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt
    28441 cagcaacaat caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag
    28501 gcacacctgc tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa
    28561 catgaccaga tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg
    28621 aattttcact gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag
    28681 ctgatagaac tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa
    28741 ctgcttcatc tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta
    28801 ccgtcgcaat ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat
    28861 tggcaattaa aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag
    28921 gataccactg gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt
    28981 gccacgacgt tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt
    29041 cttgaactta accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt
    29101 tgataactcc aacacaccag cagtttgcgc caaggcttcc ataatcagaa cacctggcat
    29161 aactgggtat tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat
    29221 agcaacaatg gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg
    29281 gtggggaaga gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta
    29341 ccaaactcaa ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga
    29401 gctgggattt cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg
    29461 acactatcac caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact
    29521 ccaacaagtg gactctctac aagatttccc tcactagcca cacttgcttc agctggagct
    29581 ggaacttctt ctgctacagt ctctgctgga gcagatgtag gagctactgg attcggtgtt
    29641 gctagaacgg gtgctggagc gacttgagtt gcaacttcag gcacaggtct cgcttcattc
    29701 ttgctaaact gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg
    29761 tcaaattgag tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac
    29821 gtttgaaagc aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg
    29881 gaatttcttt ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt
    29941 cacttgtccc agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag
    30001 cttctactgc acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag
    30061 gtacttcctt accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag
    30121 ttgacgttcc gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca
    30181 aggctagttt gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt
    30241 aggcatcaca agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt
    30301 cagcgtgttc aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat
    30361 tgcgatcctt atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg
    30421 ttaaggcttg gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca
    30481 acatcacatc ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg
    30541 atgaagagca ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta
    30601 cattcccaga agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg
    30661 gtcctttttc atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag
    30721 atgcaacgat aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat
    30781 ttacagcctc ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat
    30841 ctttttttac aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat
    30901 caaagtcact atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac
    30961 tattccaaaa ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca
    31021 ctactcgatt tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat
    31081 caatggcaac cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg
    31141 caacctgctc tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa
    31201 tcttatctga taagatagct gtcatatcag actcaatcat tcctggagca atcacattga
    31261 ctcgtatatt ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag
    31321 ccttagaagc agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca
    31381 tattaatgat agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat
    31441 taaaggcacc agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga
    31501 gcataagagt atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt
    31561 ctgcaatagc ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa
    31621 tgggaaccac cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc
    31681 cacgactgtt taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac
    31741 caattccacg actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc
    31801 tttcaaaact tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat
    31861 cttccacatg agctaagtga gcagtttgat caattttttt aacaaaacct gacaagactt
    31921 tccccggtcc aatctcgata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt
    31981 catagaaacg aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt
    32041 gcatcacagc agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct
    32101 gagctagagt ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggac
    32161 ctgacacctt aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc
    32221 gatcaactgc aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg
    32281 gagtaaccac tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg
    32341 tattgagaac tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc
    32401 cacgcttagc taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg
    32461 cagagtattc tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca
    32521 ataaacggta gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat
    32581 tgagtttgtc ttcttccgta tcgatgagat aacgtaaatc ataaccgagc acctgactcg
    32641 ctcgatcaat cgtttctttg acaatcggat actgatcata gaaatcccgt cccatcccta
    32701 gatactgggc accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct
    32761 gcccagcgag aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg
    32821 atttcttcag ctgtttcttc tttagaaaca agccctgcga tttgacctgc catgacagag
    32881 ccaccatcca catcaccgtg aacaactgct ttggctaggg cacctgctcc catttgttca
    32941 aagatttcta aatcaggatc ttcctgctta aaggcatctt tttcagccag ttcaaaatct
    33001 ctagtcaact gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta
    33061 gtatcaatat cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct
    33121 tttgcaacta caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc
    33181 gcagcacctt caccatccgc aattcctcct gcagcaataa caggaataga tatagctgtg
    33241 gctacctgtc gcaccaaggt catggttgtt aatttaccga tatgcccccc agcttccatt
    33301 ccttctgcaa taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcgacacta
    33361 ggaacaacag gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga
    33421 tttcctgctc ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct
    33481 tccacaaagg gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg
    33541 attttatcaa tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct
    33601 aatcctccag ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct
    33661 ccttggaaaa taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct
    33721 ccaaccttcc ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta
    33781 cctaaacaag agggagtggg tttctcccta ctccttctac taatattctg cttattttgc
    33841 ttgctcttca acgtaagcaa ccaagtcacc aactgttttc aagtcatttt ctgcttcgat
    33901 ttggatatca aaagcatctt cgatttctga gattacttgg aacaagtcca atgaatctgc
    33961 gtccaaatca tcaaaagttg attcaagtgt tacttctgat gcgtcttttc caagttcttc
    34021 aacgataatt tcttgtactt tttcaaatac tgccatgata ggactccttt aaaataaata
    34081 gtttttttat aacaatgtgt tcaccacatg attacctaaa ttgtaagaat gagcgtgccc
    34141 caggtcaagc ctccaccgaa gcctgataga agaacagtct ggctaccatc taaagggatg
    34201 agaccttgtt ctacacactc tgaaagtaaa atcgggatac tggctgcact ggtattgcca
    34261 tattccatca tattggctgg aagtttggct cggtcaacac caatttttct agccatctta
    34321 tccaaaatac ggtcattggc ttgatgaagt agcagataat ccaagtctgt cacctctata
    34381 ggagattcat caatagtctg cttgatagac ttggctacat ctcgaatggc aaaatcaaag
    34441 actgtgcgtc catccatctt caaaaacgaa tctgcacttt cttgatctga aaatggagaa
    34501 tgcaaacctg aatgcccata agttaaacac tcgctgcgac ttccatcgct attgagactc
    34561 tcagctaaga aatgctcttg ctcgctagct tctaacaaga caccaccagc accatctcca
    34621 aacaacacag ctgttgatcg atccgaccaa tcgactgcct tagagagggt ttcactacca
    34681 atcaccaagc ctttttgaaa gcgaccagaa gcgataaact tttcagcagt tgaaagagca
    34741 aatacaaatc cactgcaagc cgcggttaag tcaaaagcaa aggctttatt agcgccaata
    34801 ttagcttgaa cacgagcagc tgtagagggc atcatcgaat ctggagtaat ggtagctagg
    34861 atgataaaat ccagttcttt tcctgttatt ccagcttttg ccatcagttt cttagcaacc
    34921 tctgtagcca aatcactggt agattctgtt cttgaaatat gcctttgtcg tattcccgtt
    34981 cgacttgaaa tccactcatc attggtatcc ataatctgag ccaagtcgtg atttgtaacc
    35041 acttgctctg gcacataatg agcaacctga cttatttttg caaaagccat tatttcaaat
    35101 cctccaaaaa ttggtaaaga ttagtcaagc ctttacccat gacagcaatt tcttcctcgc
    35161 tcatgccatc aataattttt tctaccatgg ccttgtggaa gcgtttatgc agtctatgaa
    35221 tcaagcgacc cttctttgtc aaatgcagat gcaccacacg acgatcctgt tctgaccgaa
    35281 ctcgctcaat gtagccctta cgctctaaat tgttcaaact tgtcgtaaca gttccaagag
    35341 ttaccatcaa ctcttttgac acttgacttg gagtcacatc tggagcctta ccgatgacat
    35401 caatcgtatg catttctttg atggagatat ccttaaaacg actacctctc aagttcactt
    35461 cctcaattac aaggacattg ttaaatatag atgttaaata ttcattgatt cgttggtagt
    35521 ccatttttca tatccctcct tcttcaaaaa acttttacaa tcaaaacatt tgacagaaag
    35581 aattatatca aaattcaaag aatgatgcaa gtatttttta ttttcctgta aatttaggtc
    35641 ttcttctctc cgaatgagct cgcactcctt ctttgaaatc ctctgtttga gctaaggatt
    35701 tctgtaggtt cagttctaaa gtagcgtaac cctgccagtc tttaaactgg ctctcccaaa
    35761 ccaacttctt aatggcagca taggaattac ttgaagcacg tcttaatttt ttaagaagct
    35821 gttctctcgt cttttcaagt ttttcagctt cagaaacgcg gtaaaccaac ccccattcta
    35881 gggctttttc tgccgttaaa gcctctcctg tcatagctaa ttgagcagca cgcgtcacac
    35941 cgatactgcg gctcaagaga tgaattcccc ctgcatctgg agccaaacca acaccaacaa
    36001 aggcttggat aaacttagcc ttatccgtcg ccaaacagaa atctgccgca acagccatat
    36061 tcgctgcggc acctgcaaca gcaccgtcaa cttccattaa aacaggtttg gctatttgct
    36121 tgattttata agaaatcgta ttgaccaact ctgcgatttt tgtcaatgat ggaatatcat
    36181 cctcatccac tgcccgcttc atctctacca aatctccccc aactgagaag acctttccat
    36241 tggcattgat taagataaaa tgcacagctg gattttcttc tgccaaagtc agagcttcta
    36301 aaatctcctc acacatggga atatgaaaac catttgcgac ctcaggacgg ttcaaggtaa
    36361 ggattgccaa gtcctcttca agctgataaa taatgtgttc catcagggct cctttttatt
    36421 ttataagcag tttatactct tcgaaaatct cttcaaaccg cgtcagcttc catctgtaac
    36481 ctcaaaacag tattttgagc agtctgcggc tagcttccta gtttgctctt tgattttcat
    36541 tgagtgttaa attatttcac tgtcaaagta tatctttttt aggagcagaa agcaagaaaa
    36601 aatcgactga aagtgtctca gccgataaga aaggctcgct ttaggctaga aagcatctta
    36661 ttttcttcat tgaaaaaagc ctttctttct gctataatcg tataaaatac ttactttagg
    36721 agttcttatg aaagttgtta aatttggagg tagttctctt gcctctgcta gtcaattaga
    36781 aaaagtttta aacatcgtca aaagcgattc agagcgtcgt tttgtagtcg tttctgcgcc
    36841 tggtaaacgc aatgctgaag atactaaggt tacggatgcc ctgattaaat actaccgcga
    36901 ctatgttgcg ggtaacgata ttagcaagag ccaaagctgg attatcgacc gctatgctgc
    36961 tatggttagt gaattgggac taaaaccagc tgtgctagaa aaaatttcta aaagcattca
    37021 cgccttggcc actcttccta ttgaagaaaa tgaatttctc tacgatactt tcctagcagc
    37081 cggtgaaaat aacaatgcca aattgattgc tgcctacttt aaccaaaatg gtatcgatgc
    37141 acgctatatg caccctagag aagctgggat tgtggtcaca agtgaacctg gtcacgctcg
    37201 catcattcca tcaagttatg acaagattga agaattgaca aacaccaatg aagtccttgt
    37261 cattcctggt ttctttggtg tcactaagga aaatcaaatc tgtactttct cacgtggagg
    37321 ttctgatatt acaggttcta tcattgctgc tggtgtcaaa gctgacctct atgaaaactt
    37381 tacggacgtt gatggtatct ttgcagccca ccctggtatt atccaccaac cacactcgat
    37441 tcctgagttg acctaccgtg aaatgcgcga gttggcctat gcaggcttct cagtccttca
    37501 tgacgaggct cttcttcctg cctaccgtgg aaaaattcct ctggttatca agaataccaa
    37561 caaccctgac catccaggta ctcgtatcgt tctaaaacac agtaatgatg aatttccagt
    37621 tgtgggaatt gctggtgact caggctttgt cagcattaac atgtcgaaat acctcatgaa
    37681 ccgtgaggtt ggatttggcc gcaaggttct gcaaatcctg gaagaactta acatcggttg
    37741 ggaacatatg ccaacaggta tcgacgatct ttctatcatt ctccgttctc gccaactaac
    37801 tcccatcaag gaagaagaaa tcctgcgtca gttggttcaa aaggctaaag tagatcatgc
    37861 agaaatcgaa cacgaccttt ctatcattat gattgttggt gaaaaaatga agagccacat
    37921 cggagtgact gctactgcga cacgcgctct atctgaaaac aaaatcaaca tccagatgat
    37981 gtctcaaggt tctagtgaag tttctattat gtttgttgtc aataaagacc aagagaaagc
    38041 agcaattaaa gccctctaca atgccttttt tggagaaagt aaggaagact aagcatggcc
    38101 caatcactta acaaaacagt actcctcagt acgacaggca cttcctacct ctctatcgct
    38161 gggaaagttg ggaaattcct tgtcggagat caggctttgg aattttaccc agatgtcaat
    38221 gtcgaacaat ttatccagat tccttggagc catatcaatc agattggagc caatgtcact
    38281 ggatgcaaaa tcagccgcca cttcgaagtc tttacagaca aaggaaaatt cctctttgct
    38341 tcaaaagact caggtgccat tctcaaaatt gcacgcgaca aattgggcaa tgacaaggtc
    38401 gtcaaacttc cgaccctgat tcagacaatt agccaaaaat ttaaaaatct atttgcaaaa
    38461 aaatagaaac tttagtataa tcatagcaac ggataagtag gttatcttct tctttcagaa
    38521 agtctgcggg tgctgcgagc agataggagg gataggtgaa attctaccgt tagtaacaat
    38581 tacatacaca atcaagtgca cacctgtgaa gttggatgga accgtggccc tgccactcca
    38641 acgttttgtc aggtgtgctt ttttcataaa ggagttctta tgttagatat caaacgtatt
    38701 cgtacagatt ttgaagctgt cgcagaaaaa ttagctacac gtggtgtaga tgctgctgtc
    38761 ttgaatgaaa tgaaagaaat cgatgctaaa cgtcgtaaca tcttggtcaa ggttgaaact
    38821 ctcaaagcag aacgtaacac agtttctgct gagattgccc aagctaagcg caacaaggaa
    38881 aatacagatg acaagattgc tgccatgcaa aatctatctg ctgaggttaa agccttggat
    38941 gctgaattgg cagaaatcga tgctaaattg acagaattta caacgactct tccaaatatc
    39001 ccagctgaca gcgttcctgt tggggctgac gaagacgaca atgtggaagt tcgccgttgg
    39061 ggtactccac gcgagtttga cttcgaacct aaagctcact gggatctcgg tgaagacctt
    39121 ggtatccttg actgggaacg cggtggtaag gtaacaggcg ctcgcttcct cttctataaa
    39181 ggcctcggtg ctcgtttgga acgtgctatc tacaacttta tgttggatga acatggaaaa
    39241 gaaggctata ctgaagtcat cacaccttac atagtcaacc atgattctat gtttggtact
    39301 ggtcagtatc caaaatttaa ggaagatact tttgaactca gcgataccaa ctttgtcttg
    39361 attccaactg ctgaagttcc tctggcaaac tactaccgtg atgaaatctt agacggcaaa
    39421 gatcttccaa tctacttcac tgctatgagt ccgtcattcc gttctgaggc tggttctgcc
    39481 ggtcgtgata cgcgtggctt gatccgtttg caccaattcc acaaggttga aatggtcaaa
    39541 tttgccaaac cagaagaatc ttacgaagaa ttggaaaaaa tgacagccaa cgctgaaaac
    39601 attcttcaaa aactcaacct tccataccgt gtcgttgctc tctctactgg agatatgggc
    39661 ttctcagctg cgaagactta cgacttggaa gtgtggattc cagcacaaaa caattaccgt
    39721 gaaatctcaa gctgttcaaa cacagaagat ttccaagccc gtcgtgccca aatccgttac
    39781 cgtgatgaag cagatggcaa ggtgaaactc cttcatacct tgaacggttc tggacttgca
    39841 gttggacgta cagtggctgc aattcttgaa aattaccaaa atgaagatgg ttctgtgacc
    39901 atcccagaag cacttcgtcc atacatgggt ggagctgaag tcatcaaacc ataaaaaata
    39961 aggtttagct atttctagct agaccttttt tcgtaaccaa atcagataag cacctagtac
    40021 aaagaataaa atagttaggc atataatggt ttcagccaat accaggtaat ccagaaatgg
    40081 aagtttcaaa attccctgag ccatcttgag cgaggtcgct gtgataatgg ttgggaaggt
    40141 gagggctgag aaggctggtt gaaaaccttg ttttaaaatg ttgggcagac gagttaaaac
    40201 aaagaaaaag aaggattgag aagccaaaat catgacaatc aagacccaat tcggcaggct
    40261 ggttcctcct actcgaacta gagaagccaa gagtagagag aaaggagcac agtagattcc
    40321 ttcttgtcca agcaaggcta gtgggagtgg atgtttcttt aaatcgctat aaataagggg
    40381 atagagatag aaggtcaaga gaaaaccaaa actcaaggtc gcataggcaa tttcgataat
    40441 acctaccaga ggataggtca aggcagccac tgctatcccc acatagagaa ccgtccaact
    40501 tggagtggca tgaaccctcc gccctgaaca agcaaacttg atggtaaaac cagcaatcaa
    40561 ggtcaaatcc aagagaaatg aaaaccacca aatcccttgt gctaccaaag gaagataaga
    40621 gaatacgcga aagacatagg tcgataaaat catcccagcc ataggaaagg ttgccattcc
    40681 tgacaaaaga gggggcttgg tcaattcttg cttggtttct ttccaattaa agagatgcag
    40741 aattagaaag taaatccata aaaccaaacc agtcagacta aaaagatggg atagaaccgg
    40801 caacgtatct aaaataagat ttccagctcc tgccaaacct agcaaacaac ctgaaaatac
    40861 taaggggagt tttttcatcc taacctccaa taatcatgtt agtttcagta taacataaaa
    40921 gcgcttaaat gatgatttaa aaaaacgaag tccgattatt tcagacttca ttttactcag
    40981 atatgaatta ggcataaggt tgcaattctg gattaattgg tgtattagct aagttgttgg
    41041 catagttaca gaggattgct aggctgacac caaaaaccac atccaaggca ttttgttgag
    41101 tgtagccagc ttctaaaaac tcagacaagg cttcatctcc tacacgaccc ttggtattga
    41161 taactgccaa ggtaaactta gctagggtat ccaatttagg atctgtttca attggagtac
    41221 gattgcgaag agcttgaatc aagtcatcat tcatctggat ttgtttgatg gaaaaggctg
    41281 tgtgacctgc gacacagaag gcacaaccat tggtcacggc tgccgtgatt tgcaccactt
    41341 cacgctcaac gggtgtcagg ctgttgcgac ggtggataga tgagacaatt tggtaggctt
    41401 ctaaaacagt cggggcattg gccaagagac cgattaggtt gggaatatag ccattgttgt
    41461 ctttttctac tgtttcaaga atttctttca cttctgctgg tgctgactct actgtatgga
    41521 tagtaaatgt tgtcataaga tacctctttt cttattattg acactaatat tattggaaaa
    41581 tcttataaaa tcctgattcc taagtttatc taagataaag ctttattctc tcataagatt
    41641 ttcgttgtta tattagttta tcacacttcc aatcacttgc ataatatata ttatatatca
    41701 ggctgataaa aattatttat aggcaaaaaa atcacacgag ctgtgtgatt ccattatttg
    41761 tcaaaatact ttttagtttc agcaataacg acttgcgaca agaccaagag ggcaatcaag
    41821 tttggcagag ccatcaaggc gttaacgata tctgcgataa tccagaccat atccaactcg
    41881 ataaatcctc ctaacaagac catgagcaca aaaaccacac ggtagagcca gataaagcga
    41941 accccaaaga ggaactcaaa acagcgttct ccgtaatagt tccaacctag aatcgttgta
    42001 aaggcaaaaa gtacaaggaa gatggtcaag agggcaggcc caaagtgtga aaagactgtt
    42061 gagaaagctg actgagtcaa ggcaacccca ttcaagtcac cactccaaac tccagttacc
    42121 aagatggtca aaccagttag agtacaaatg atgagggtat caataaaggt tcctgtcatg
    42181 gaaatcaaac cttgctctac tggttcattt gtcttggcag ctgcagctgc aataggagca
    42241 gaacccagac cagattcgtt tgagaacaca ccacgcgcca caccattttg aatagccatc
    42301 cgaacgctag caccagcaaa tccacctacc gcagcaaggg gactaaaagc tgaggtaaag
    42361 actaaagcga ttgtgccagg gatttttccg atattaaaga aaataactat aagagttcct
    42421 aagatataaa tgatggtcat aaaaggaaca acagtagttg aaaccttaga aatagacttg
    42481 agtccaccaa agactgcaat cgctacaaag acagacaaga cgagagctgt gatgactggc
    42541 gaaatcgtcg ttgtattttg gatagattct gtaatcgagt tgacttgggt gaaggttccg
    42601 attcccaaga gagcaaccaa tactcctgct actgcaaaca aaacagcaag tggtcgccac
    42661 ttttctccca tccctagaag gatatagtgc atgggacctc ccgctactgc accatggtcg
    42721 tccttggtgc ggtatttgat ggccaagagt ccttccgcat acttggtagc cattccaaag
    42781 aaagccgcca tccacatcca aaatagagct cctggtccac caaccttgat agccgtcgca
    42841 actcctatga tatttcctgt tccaacagtt gatgccaagg ctgtacacag agctgcaaaa
    42901 ctggatacat caccatgtcc cttatcctgg ataaaaataa gctgaaaggc cttgggcaga
    42961 cgcaaaacct gcaagagtcc tagccgcatg gttaggtaaa tccctgttcc gaccaataaa
    43021 atcaagaggg gcggtcccca agcaaaatca tcgattgatt taagcaattc taacatttcc
    43081 ttctcctatc gtttcaaccc caaaagaaag agcacatgca agatacatgt actctggaat
    43141 gcttagataa atgctaaaaa gcggtctatc ctagctctgt ccttttacct gagagtttga
    43201 gcagttgcct gccttgcccc ttcggtgcct ttacggtctc tccagagttc cgtccattta
    43261 cagtcatgga aaatcaaacg attccccact tctattaaac ttcattcggt gttggtattt
    43321 aattgattct aattttacaa aaaatgttgg cttttgtcaa tgtgtttatt agtaaaaatt
    43381 agttcaacag tttttacttt ataaagtcca gaatactgct atcctttaaa agtgacaata
    43441 gtcgcaccac tgcctccagc attttgtggg gcatagccga aactcttgac atgtttgttt
    43501 ctttgcaagt atttggtaac tccttcacgg atgactcctg ttccgatacc atggatgata
    43561 tcaacttgag ccatattgtt aagcaaggct tggtcgatga aggtatctag ctcattcatg
    43621 gcttcttcat agcgcttgcc tcgaagatcc agtctagctt gaggtcctcg cccagaagtt
    43681 cgtttcacaa cattgacctg tttcttcttg actggttttt cttgctgggc ttgaacaaga
    43741 tcaaactctt tctcttccaa ggtcatctta atcaagccaa cttgggcttc ccagcggccg
    43801 tccttgagtt gactggtcaa ggtaccacgc tgaccataac tgagaaccac gatatcatct
    43861 cccacctttg gagctcgttt tttcttggcc ttttgaagga ccttgttttt agacaagtcc
    43921 actttttcag gagccaattt tttcaacttg gccttggctt caatgatttc gtggggcttg
    43981 agttgggatt tactgtggag atttttgaga atctggtcac tttcacttag ggccatatcc
    44041 acaatctcag cagcctgttc acgcgccttg ttaagctcgg tttccttttc acgattaagc
    44101 tcgttgtaga gtttttttag cgcacggttc atcttgagat tttcttgctc cacctcacgg
    44161 atattgtcca aacgtttgcg gctttccagc gtctgctctt ctaattgctc aatgatacga
    44221 ttgacgtcat tgtcctgatc gatctgctga ctggcatctc ctacgataac ttcagatagg
    44281 cctagacgtt tggcaatttc aaaggcatta cttcggccag gaacaccctg cataaagcga
    44341 taggtcgggc gaagagttgc agtatcaaac tccatactgg cattttgcac aaaggctgtc
    44401 tcaataccgt aggccttgag ttctggatag tgggtcgtcg ccatggtctt gatttgacgc
    44461 aggcgaaggt cctccagaat agccatggca agggctgctc cctcttgggg atcagtacca
    44521 gcccccaact catccaaaag taagagtgaa tgttggttga ccttgccaag aatatccacg
    44581 atattggtca tatggctaga gaaggtagac aagctctgct caatagactg ctcatctcca
    44641 atatcagcaa agatttcttc aaaaatacca acacgacttc ccttgtctgc taaaatcggc
    44701 aatcctgact gggccatgac ctgtgtcaag cccagagttt tgagcatgat ggtcttccca
    44761 cctgtattgg gacctgtaat gacaatagct gttaaatctt gaccaaaata gacatcattt
    44821 gcgacggcat ttttgaccaa aggatggcag acatggagca gttgaatctc ttgattttct
    44881 gacagctgag gcacgactgc ttgtctttct tggataaatc gaaccttggc acgaatcaag
    44941 tccagatgac cgataatcca agcgtcatta gcaatctcag ccgcatgagg gcggacacgc
    45001 tcagaaattt cttggagaat gcgaagcatt tcatagcgct catctgctcg cagactagca
    45061 atttcttcgc tcagtttgac tacctcacgt ggttcgatat agacggtgtt tccactagca
    45121 gaaatatcat gaacgacacc tgcaatctta ttgcggtagg tgtttttgac tggtaaaacc
    45181 tgacggccat ttctgctagc aacaattcct tccgtcaaca tctgcgcttt ttgcttgagt
    45241 aagtcttgta aaacatcgcg cacctgactc tcgctatcat gtatttttcg acggattcgc
    45301 gccaattctt cactggcaaa attttcaatg aaacccgcat cattaaaggc ctgaagattt
    45361 ccttgtaatt gcggaaaatc atgtaatttc tcaaaccaaa gggctaattc ttccaagctg
    45421 acattttcca gattggcgta aaaattttga agttctcggc tggcaagaag cacgcgtttc
    45481 aagagtagga actcctcgat attgagatcc gctcccatct ccaacctctt gcagactcct
    45541 gcaatttcct tagttgagag aatagtaaaa tgcggttgct cgacgaaaag agcctgcatt
    45601 tctttcatct cagcaaaagc ctgtttgatt ttatctgctt tggcagtcgg agccagctgt
    45661 ctcaattgct ccaagccctg ctcggtcaac aaatgaggct caaacaaggc cttgacctta
    45721 tcgaactcta atgtttctaa tattttctta ttcatcttta tttccttgtc tttgaatgtc
    45781 taggtgtggt agctttttac attctgatag attcgagtca aatctgtaaa caaagggcta
    45841 ggaaaactcc tgcccttttt atccgattaa atttgtcacc cagatttgtt tgagccaact
    45901 ggttgttacc ggtatgctct ggatgatgtg ttttgcgacg atactctttt caagaggatt
    45961 ttgtataact gccatgggga tggtcgccaa gattgtcaag gccatttgca agacaaataa
    46021 ggtcaccaac atggacaaga tacctgctga aacttggaac aacttaccac ccagtttttt
    46081 gctaggaatc aagtgtaaga gaagaccaag taaacgacca atgctataga caatcccaaa
    46141 tacaagcaag tagccgatac ctgcataaaa gaccttatcc agctgaaaga gttgatccga
    46201 tgggaaaaag aaagtcccct gaccttcctg cgaatttgca taagggagca ataaatggaa
    46261 ttgctctcca agccccttat aaaactggcc agccataaaa gccgatgcca tggctgaaat
    46321 caggtaataa acctgtaaga gcaggcctct ccgatagccg atataaaatc cccaaaccaa
    46381 gaccaataga agaaggaatg aaatcataag gaatcctcaa tcttgctctg ttcttgctta
    46441 caagtcacaa gcttgtgacg gagttcttct agctcttgct ccttatcgtc aaattcaatc
    46501 tcacggctga gctgagttga taaacagttg actgccaaca aaagagcgat tgtttcatca
    46561 tctgcgctag gcatttgttc tttaattgct tggtattttt ctgtcgcaac cttagcgatt
    46621 tcctccataa aaaggttgtc atgttcgctt gtcaaggtta acgatttttt cccgaatgta
    46681 aatttgaatc gatttagatt tgccataaaa ttcacctcac gatattatac caaaattcgc
    46741 taattttgtc agtttttaca aattttactg cttttgtggt acaatagaaa ctatggcaag
    46801 tatcacactc acaccaagcg aaaaggatat tcaggctttt cttgaacact atcaaaccag
    46861 tctggctcct agcaagaatc cctatatccg ctactttttg aaactacctc aagcaacggt
    46921 ttctatctat acttctggaa aaatcttgct tcagggtgaa ggggctgaaa aatacgccag
    46981 tttctttggc tatcaagctg tagagcaaac cagcggacaa aatcttcctt taattgggac
    47041 agatgaggtg ggaaatggtt cctactttgg tgggcttgca gttgtggctg cctttgtcac
    47101 acctgaccag cacgactttt tacgaaaact cggtgtgggg gattctaaga ctctgaccga
    47161 ccaaaagatc cgtcagattg ctcctattct caaggaaaaa attcagcacc aggcactcct
    47221 tctctcaccc agcaagtaca acgaggtcat cggagaccgc tacaacgctg tttcggttaa
    47281 ggttgccctc cataatcagg ctatctatct cctccttcaa aaaggtgttc agcctgagaa
    47341 aattgtgatt gatgccttta ccagtgctaa aaattatgac aagtacttgg cacaagaggc
    47401 caatcgtttc agcaattcta tcagcttaga agaaaaggct gagggcaaat acttggctgt
    47461 cgcagtttct tctgtcattg cgcgtgatct ctttctggaa aatcttgaaa atttgggacg
    47521 agaactgggt tatcagcttc caagtggagc tggaacggct tctgacaagg tggctagcca
    47581 gattttgcaa gcctatggta tgcagggact caacttctgc gctaagctac actttaaaaa
    47641 tactgaaaaa gcgaaaaacg cttagaaagg taagttatga atttatttaa aaatttctta
    47701 aaagagtggg gattattcct cctgattctg tcattactag ctttgagccg tatctttttt
    47761 tggagcaatg ttcgcgtaga aggacattcc atggatccga ccctagcgga tggtgaaatt
    47821 ctcttcgttg taaaacacct tcctattgac cgttttgata tcgtggtggc ccatgaggaa
    47881 gatgggaata aggacatcgt caagcgcgtg attggaatgc ctggcgacac cattcgttac
    47941 gaaaatgata aactctacat caatgacaaa gaaacggacg agccttatct agcagactat
    48001 atcaaacgct tcaaggatga caaactccaa agcacttact caggcaaggg ctttgaagga
    48061 aataaaggaa ctttctttag aagtatcgct caaaaagctc aagccttcac agttgatgtc
    48121 aactacaaca ccaactttag ctttactgtt ccagaaggag aataccttct cctcggagat
    48181 gaccgcttgg tttcgagcga cagccgccac gtaggtacct tcaaagcaaa agatatcaca
    48241 ggggaagcta aattccgctt atggccaatc acccgtatcg gaacatttta agaaacctaa
    48301 gaggccgaga atcaccaatc tcagcctctt cttctatcgt gagaaaatga ttggtaacta
    48361 tctaaactta ccagaacaga aacacctcaa ctctcaccta ttcatgcaaa ggaattttat
    48421 ggaagtttat ttttcaggaa ccattgaacg gattattttt gaaaatccca gcaattttta
    48481 tcgcatcctc ctcctagaaa tcgacgatac ggacgcagag gattttgatg attttgaaat
    48541 cattgtcaca ggaaccatgg ctgatgtaat tgagggcgaa gactatactt tttgggggca
    48601 aattgtccag cactccaagt atggagaaca actgcaaatc agtcgttatg atcgcgcaaa
    48661 accaactagt aagggcttgg tcaagtactt ttcaagtagc catttcaagg ggattggtct
    48721 caagacagct cagaaaatcg tggataccta tggcgaaaat accattgacg aaattttgca
    48781 acacccagaa aagttagaag gcatcgcagg attctctgcc aaaaatcgcg aggctttcgt
    48841 ctccactctc cgtctcaact acggaacgga gatggttttg tccaaactag ccaactacgg
    48901 cattcccaac aaactagcct ttcagattca agacttttac aaggaagaaa cccttgatgt
    48961 ggttgaaaat tatccctacc agctggttga ggatatcaag ggtttgggct ttacaattgc
    49021 tgaccaacta gctgaggaac taggcatcga aagtcaggct cctgaacgct tccgcgccgg
    49081 tctagttcac agtctttttc aggcctgtat ggaaacaggg gacacctatg ttgaagcacg
    49141 ggatttgctg gaacaaaccc ttactctcct tgagtcttcc cgtcccgtgg aactagaccc
    49201 cagccaagtt gcccaagagc tctcctacct gatcgaagaa gacaaggttc agcagattga
    49261 taccaagatc tttgacaaca gcctcttttt cgctgaggaa ggtatccgca gtcacttgat
    49321 tcgtatcctt gaaaaaggaa aacagaagag ccaagattta gaaactattc aaaagcatat
    49381 cactactgtc gagcaagagc tgggaattga gtatgataac attcaaaaac aggctatctg
    49441 tgatgctatc cagaataagg tctttatcct gacaggtgga cctggtactg gtaagacaac
    49501 tgttatcaat gggatcatcg ctgtttacgc cctgttagag ggacttgacc tcaggaagaa
    49561 aagcaatctg cccattcttc ttgctgctcc aactggacga gccgctcgcc gcatgaatga
    49621 attgacaggt ttgcctagcg cgaccataca ccgccacttg ggaatgacag gtgacgatga
    49681 taccagtcat ctggaagatt acctagatgc tgactttatc atcgtggatg aattctctat
    49741 ggtagatact tggctggcca atcaactctt ctccaatatc tcttctaaca gtaagatcct
    49801 catcgtaggt gacagtgatc agctaccttc tgtcagtcct ggacaggttc tagcggatct
    49861 gcttcatatt cctttgattc ctcagactcg cttggaaaaa atttatcgac aaagcaaaga
    49921 atcaaccatc gtcaccctag ctagtcagat tcgacagggc atcttgccag ctgatttcac
    49981 ccaaaaaaaa gctgaccgtt cctactttga aattgctagt ggccatattc ctgccaccat
    50041 tgaaaaaatc ttaggtgtcg ccctcagaaa tggtattcct gcccgtgata tccaagttct
    50101 ggctcctatg taccgaggga cggcagggat tgatgctatc aatcagctca tgcaagacct
    50161 gctcaatccc ccacaaaaag atcaactcag ttttgaagct cctcagtgcc actatcgtaa
    50221 gagagacaag gtcattcatt tggttaacga tgctgaaatc aatgtcttta atggggattt
    50281 aggagctatc acagacctga ttcctggtaa atacaccgaa tcgaaacaag acgagattgt
    50341 cattgatttt gatggtaatg aagtctctta cccccgtaac gaatggtaca agattcgctt
    50401 ggcctatgcc atgagtattc ataagtctca gggaagtgag ttcccagttg tcatcctacc
    50461 gattactagt gctagccgac gtatgctgga gcgaaatctc atctacacag ccattacacg
    50521 tgccaaaagc aaactcatct tactaggcga attacaagcc ttcgactatg ctacccaaca
    50581 catcggaact gcccgaaaaa cctatctgat tgaacgcttc agtgatctac tggagaatgt
    50641 tgaagaaaag caacaagctg tctctgaaac agtcacatca agtgcctctg aacaatccta
    50701 catcctaacc gaagaaaact gggaccgcat cccagccatg attgggatta cagacacaga
    50761 cctcaaagag atttttggaa aatagtgcat cagaaaaccc accaattcag gtgggttttc
    50821 tgtttattaa gattatttta ctgttgctgt gcttgtgatc aattcaacag cttttttgat
    50881 agtgatatca tgtttcaaca tgtcagctga aagcaagttt tgaacttgtg caacttccat
    50941 gttgtagtct gctgccaatt gctcaacttc tttttggatt tcttcttctg aagcatcaaa
    51001 tccttcagct ttggcaactg cttcgataac aaggttagtc ttagtacgtg actcagcttc
    51061 tgcttggtat tggttgtgaa ggtcttcttg agtagttcca gtgatttgga agtacatgtc
    51121 agggttgatc ccttgacgtt gcaaattccc aaggaattca tttactgaac ggtgaacttc
    51181 ttcatggatc atttcttctg gaagttctac gatttcagca ttttctacag ctgtatcaat
    51241 tgctgcacct tcaactgcat ctttgtaagc ttcttcttta gcagcagcca attctttgcg
    51301 gtatttttct ttcaagtcag caagtgtttc aacttcttca tcaatgtctt ttgcaagttc
    51361 atcgtcaaga gctggaactt ctttagcttt tacttcgtgg atagttgtca cgaatttagc
    51421 ttctttacct gcaaggtctt ctgcttggta gtcttctggg aatgttacga taacatcaac
    51481 ggtttcgcca gctgagtgac ctaccaattg gtcttcgaaa ccagggatga attgacctga
    51541 accaagtcca agtgagaagt tttcaccttt tccgccgtca aattcaacac cgtcgataga
    51601 accaacgaag tcgatcacaa cagtgtcgcc gttttcagca gcagcttcct tgataaccaa
    51661 ttcagccagg ttgttgcgtt cgcgttcgat acgctcttca acatcagcgt cagttacttc
    51721 tttttctaca tcaactgata cttcaaggtt tttgtagtca cccaatttta cttcaggttt
    51781 tgtaacgact tcagcagcga taacccagtc ttgacctttt tccattgaag ttacgtcaat
    51841 ttttggttgg gcaaccactt caagaccagc ttcttttaca gctgcttcat aagcgtttgg
    51901 caaaagagcg ttcataacgt cttggtaaag tgattcttca ccaaattttt tatcgaagat
    51961 aggacgtgga aggtgacctt tacggaaacc tggaacatta agagatttct tcactgactt
    52021 gaagacacgg tccaattctg gtttgatttg gtcttgagag atagtgaaag tcaagacacc
    52081 acggtttgtt tctttgtttt caaatgatac agacattctg tcatttctcc ttaaaatttt
    52141 ttaaatacag tctattataa cattttctat aaataaaatc tagactaatg cagccaatta
    52201 tagacaacaa gcctttttcc taactaaaac actcataaag tatagacaat tttagactac
    52261 tttggatatc ttttggttag tcattttcca aaactaattt atctaatttt tcagttatat
    52321 ttgacttcat cttctcagta acatgagtat aaacacttaa aatctttgtt tcattagtat
    52381 aatctacacg atccattatc gctgttatag gtacttccaa ttcagcaagc aaacttatat
    52441 gcgaatatct aaaaacatga gcagtcaata caaaatcatc tttcttaatt tcacttttcc
    52501 taaaactgtt tttcaaaaag taattgaaac aagttatcat taagggagaa ccattatttg
    52561 taaatatata atcaccttct tctaaaagaa gatattcttt taaaatttct aacactctat
    52621 cactaatacc aattactcta tatgaagcta aacttttcgg actatccaaa aatacttcgt
    52681 tattggacga ttacattata gtaaaacgaa ataagaacag gacaaatcgt tcaggacagt
    52741 caaatcaatt tctaacaatg ttttagaagt agaggtgtac tattatagtt tcaatctact
    52801 atacaagacg aaattgaaga aatctttcca ttataaaacg catattatca aggtttttaa
    52861 acacctaata atatgcgttt tttcctattt taaagacttt tatccaccta ttatacaaag
    52921 ttaagtatcc atcacagttt acaattagcc ttcattacct aacccattca ccatccttca
    52981 agagagtaac ctttaagaac cgaataaata aatggcaaat ttcgttcatt taatttaact
    53041 gcactgttaa tttgattagc tccatctcct aaagtatgca ctcctactac acggtgacta
    53101 gcatcataaa ctgtagatcc actagacccc tctaaagtat caacttggta atccaagaac
    53161 atgccatcat cacttaaaac ttgtttttta tctgtataca tttgatgaat tttaaaatta
    53221 tatgatagat agcctgtgat agtcacagtt attcctgtca aatttttttg actagtagga
    53281 agacccaaag tccctaattt tgcaccaatg ggctcttcta gaattaataa agccaagtca
    53341 tattcccttg catccttaga atttaaattt ctaaattcct tcaaataacg aacttccttt
    53401 actttgatct ttccaaatag ttcttgactt ggactaacag ccggaagaac ataaatatca
    53461 tccgcttctt tcccatagtc atgtctgtag tagttgtgag ccgctgtaat taacacatta
    53521 tctttaataa aattcgcact tcccctccct tctacattca ttccatcggc tactccataa
    53581 tacttagata aaaccatagc tgaagtcgaa tacggatact gtaaagtatt atcaatttta
    53641 atcaaatcat cattaccgat aatacttctg attgcttttg gtagtatgaa ccatacgttg
    53701 gtgaaatctc agataatgaa gaatcattag actctggacc tttttctagt gtctcactta
    53761 cctcatattc ttcacctgta ctagaaataa cactcaaagc agatactgtc gataactggc
    53821 tagccaataa agtactcgca ataattgaaa tacccaattt tttataaaca gttttcttca
    53881 ttattgtatc ctcctaatgt aattatagcg tactattcta aatttcttaa tctactatag
    53941 aatcaagaaa tctaccacct tctttaaata ccctccatta tcacataaac aggtaaactt
    54001 ttcaattaat gactgcgctt ttcaatcacg ctagaggtac ttgcttgctt ctttgatact
    54061 aagttcagcc attctttcct tgtttttctc aataaagcat gttacccaag tgggattcgt
    54121 tttggagtag tctcgcagag tccagccaat ggctttattg ataaaaaatt ctgtttggtt
    54181 caagttatga agtagaatct tttccattaa ttgagtattg gtcttctctt ttcttaacaa
    54241 ctggtggtca atagcgacac gtctcagcca gatattatct gataggctcc attttatact
    54301 caatgaaaat caaagagcaa actaggaagc tagccgcaga ttgctcaaaa cactgttttg
    54361 gggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtatta agattatttc
    54421 ttctagttca gagtgttcat acaccaaact ccctactact cgatctagga tatctaccgt
    54481 gtcccaccag gattttgtca cgactaactg ctctagctta ggcaaatcgg tttcctttag
    54541 ataagactgc attgctttca aatagttagc agccacatat tggtattctc taggatcctt
    54601 ttcccagcaa gtgtctgcaa aatcccaatc gataatcttt gtttttttcg cttctggaaa
    54661 atatttttat agagtttatt tctttcaggc accgcaatac ctagaaaaga aaattgatgg
    54721 cgcatatagg cttccatgga ccttgctttt ttagagtctt ttgctgcttc tagctcctca
    54781 agtaaatctg ctaaactcat ctaaaactcc tcttgcccca ccaaatggtg ctgaaaggca
    54841 tagacagccg cctgggtacg atcgctgact tcaagtttgg caagaatatt ggacacgtgg
    54901 gtcttgaccg tcttgagaga gataaagagg tcatctgcga tgcgctgatt ttcgtagccc
    54961 ttggcgatga gttggagaac atctcgctca cgcgcagtca attcttcatg aagttccata
    55021 tgattgcggt ggtattcaac cttcttgcta acctcttgct caatggccag ctcgccagca
    55081 gctaccttac tgacggcatg aagcaattca tctgcactag aagtcttgag catatagcct
    55141 ttggcaccag catctaagac tggcatgatt ttttcattgt ccaaataaga ggtcacaatc
    55201 aaaatcttgg cttcaggcca ttctttaagg attgctaagg tcgcgtcaat cccattcatc
    55261 tcaggcatga caatatccat gacaatgaca tctggacgca gttccaaggc caagtcaatc
    55321 ccttgagacc cgttggacgc ctcacccaca acttctacat cgtcttggag gtcaaagtag
    55381 cttttcaagc ccaatcggac catttcatgg tcatctacta gtaaaatttt catctttact
    55441 cctttatcat tccttatcta acaggggaat acggatatca accgccagcc cttgcttggg
    55501 agctgtcaag agttgaactg ttccagccat atcttcaacc cgctccttga tatttcgcag
    55561 tccataactc aagtcgtcta agctccctaa ctggaaacca atcccattgt ccaccacctt
    55621 cagttgcaat tcaacatctg tctgatagag gtagacatct aggcaagatg cctgggcatg
    55681 gcggagggta ttgctaatca actcttgcag gatacggaag atatgctcct cgattttctt
    55741 aggcaatttc gtcatattct gcttgagact aaccctaaga tcactcttgt cctcaagctc
    55801 ttttaagaga atttgaatcc cttctatcaa gctcttctgc tccagttcaa ctggtcgcaa
    55861 atgcaagagc aaaacccgca aatccttctg ggcagtttct aaaatagctg tgacactctg
    55921 caactggatc tgcatctttt ctctatccaa tttcaaagcc tgctgactga tacccgataa
    55981 aatcatgtgg gccgcaaaca actcctgact gactgtatcg tgcaaatccc gagcaattcg
    56041 cttccgttcc ttctcgatga tttcctcttc ctgagcaagg ctatgatttt cagctttttg
    56101 aagagcttct gtcaaaaggt taagtttacc tgataaggac ttgaaactgg catccaaatc
    56161 tggatctgca acctgaacca cttcttgccc tgccaataaa cgcttgagat tagcctgcat
    56221 ttttcttaga gaaagctctt cgatccctcg ccaaaacagg gctaagagac aggttatgga
    56281 catgctgaaa accaacaata aaaagacaaa tttttctgtt ttttcgacat cgtgcaaaaa
    56341 gatagaccag tcaaaatcaa gtatttccag caagctgtgg gagaaaaaaa agacaaacag
    56401 gaaggaggtg agagcaataa tgacataggc ttgttttttc atcctctaac cacctccaca
    56461 tcaccaatca tagtggtcaa gaaaatcttg acactcttgt tactcttgag atagtctttt
    56521 gtttcttgat gatagtgttc attgcggagg gctcgcttgg gctggttgaa aaaagtcaaa
    56581 tccccataga gacagttaac gctgagactg acttccacat ctacaggtac gatgattttg
    56641 gtcgttccta ccatctttct gaggataatg acattgtcat gattggttaa gatgaccctc
    56701 tccagatgaa tagtgtcctt gcccatgaag cgaaagagat tgatatcatc gaattggcaa
    56761 gtctggtagc ttgaaaaatg atgaagattt ccaaaccaac gatttttctc cttcttaacc
    56821 gtcacgacct cttcaaaaac caaattggtc tgctcttttt cctggttcat catcgggtaa
    56881 agaagaaaga ggctatagat aaccgcaaca aaaatagcta gaatcacaaa aggattgagc
    56941 ataacgatga aaaagaagag aatggttgcc gctactaaaa gaagattatt tccctcttta
    57001 ccagtgtagt agcgaatcaa aagcaaaaag aggaatagta tcagcagaaa acgcgaaaaa
    57061 tgctctgata ccatcaaaat cagagctcct gtcagaagac aggcttcgat aaataaaaag
    57121 attttaaatt ttctcatagg ttcatcctct cccttctatt ttatcacaat tcaaaaaagt
    57181 cacctcagtc tgaggatgga aaaaaggcgc tggttacgcc tttttcatct gatcctttgc
    57241 ttcttttaat tttccataaa gaagatagtc tactttttgt agatctgcta tggtggcaca
    57301 gttaagggaa cacataatca agcgtaggtc tgctttccag ccttggacaa tgccaatcac
    57361 ttcttcaact gtgtaggttt caaccaattc cagaacggtt cgtgacaatc ccacagactt
    57421 agcaccaaaa accaagcact taatcatatc cagcggattc cgaacccctc cactaaccaa
    57481 gagttcgacc ttatctttcc attcttgggc attgagaagg gcctgcatgg tagactgacc
    57541 ccattgattg aggtaatcac gctggccact acgacggttt tcgatatagg caaagctggt
    57601 gccaccacga cccgataggt ccactgtacg aacaccgaat tcataggctc tttcgattgt
    57661 cttggcatcc attccaaagc ccacttcctt gaggacaata ggaacgggaa tttgctcgct
    57721 ataatctgct agatgcgatt gccagcttct aaacttcctt tctccctcgg gcatgagtaa
    57781 ttcctgcatg acattgacat gcacttgcaa tagaacagga ttcatctctt ctacagtctg
    57841 aagccctaac tcgacaggct tgtccaatcc aatattggtt ccaaggagga gattgggatg
    57901 actagacttg acagaaaaag aatcatccgt tggatttttg agggctgcgc tataagaacc
    57961 cgttacaaat aaaataccac aggattccgc cacctgagcc agcttttgat tgatttctct
    58021 tcccttatta cttccaccag tcatggcatt gatataaaaa ggaaagtccc actttcgacc
    58081 agcaaactct gtcgaaagat cgatttcatc cagattgtaa agaggcaagg aagaatgaat
    58141 cagctccacc tcatcaaagc tattatagga acttttctgc tcaagggcat agaggatatg
    58201 ctcgtcctta cgatttgtcg tcatgtccta tcctttcttg atataagagc tcaatcccca
    58261 gatcggccca acgatttttt aaggtttcgg ttgattgcgc atcaaaactc aaggcgatgc
    58321 cacagtcacc accaccagca ccactactct tggcaacggc ctgcaaatct tgactggctt
    58381 ctttcaactg tctaagcaaa ggcgtgtaaa tatctgtact caagccttct aaaagcttgc
    58441 tggctacttc tacttgctcg ataacttttt cggctttccc ctgctccaag gcttcgacca
    58501 aagaaaccac cgtttctttt gaggaactta aaaaattttg attgatattt tgcttgattt
    58561 gctggaccat gtgactcgat acagccactt ccttggtcca tcccactaag aaatcacatt
    58621 ctaaagttgg tttcacttgt gagataaaaa atccccaatc acgctccaga actgtcgcca
    58681 agttttcttc ttctaaccaa gcagccacct tctggcgatc aaatgactgg tagagaacca
    58741 aatcctctgc cacaatacag gcaaggtcgc ccatggaacc attgtctcct cgcttgagca
    58801 agacagcgct agtcagcttg aacaagagat tctgatcaac cgaaagatta tagagagcca
    58861 gtaaagcctt gacaaccaag acaacgacgc tgccactaga acctagacca aactttttcc
    58921 cttctcgttc cattttgcca cagattttta gggaaaaagg tcttaaattc tgaccgcgaa
    58981 cagcgaggaa gtctcccatc aaagcaatcg tttcttgaat caagctgtag tcaggattag
    59041 gccttaagtc cactgcgaaa tcaaacatat ctgaatagat acggtagctg tcagaaaaag
    59101 caatttcagc cctcatatag atgggaatat cctttatcaa agctaactgc cctggctcta
    59161 aaatagcata ttcacctgcc caatagagtt ttccgcaagt tttaacagca atcatcttga
    59221 ctcaaatcct ttgtttttga cacaatcaag cgataacgct gaccgaaaat ttctgataaa
    59281 tgctccaagt ctttctcctg acagaagacc ttaacattgg gaccagcatc catggtaaag
    59341 tagcaggcct ctcctttctc acgaagctgg cgaacaaagt ccatagcctc ataagaggca
    59401 tccgtcagat aagaaaaggc tggactagca gtctttgtcg tagcatgcat agccagggca
    59461 tttttctccg ttaattctcc aatcttggca aaatcatttt ccttgagata aatcagcata
    59521 tcctgatagt ccttctcaga ctgacgaacc cagtcgtcga aagtcgtcga ggtttccaca
    59581 caaagtttca tcccgtcacg gctagagatt ggttttttct tgtcctctag caccaacata
    59641 atcatagcta gtttcaagtc tgtctctaca gggtaaattt ctccactatc cttatcccag
    59701 gctcctagtg gtccataaaa actccgagaa gaagagcctg aggcaaactt ggcttcctgc
    59761 gctaactgac ttctatccaa tccaagcttg aaataagcat tacaagcctt gaccagggcg
    59821 gacaaaccac tagaacttga ggacaggccc gctgccgtag gcatattgtt ttgagtatcg
    59881 atacggacaa agccctcacc agctggacga taacggtcaa taatcttact catcttggca
    59941 tgctcgacct cattttgtag ctgaccattg atgtaaaatt cgtcagctgt tacattggct
    60001 ggtaaaggcg acaaggtcgt ctctgtatac atattttcca aagttagaga aatactgcta
    60061 gtagcaggca ccatctcttt ttcttttttc tttccccaat atttgataat agcaatattt
    60121 gcgtaggaac gtactgttac aggctctcta tccatgtctg aacagctcct ttctcttcta
    60181 atctttctgc tagttcttgt gcgtgtgtca aattggttac caaggctatg atacaacctc
    60241 ctagcccacc accgctcatc ttggcaccca gagcaccatg gctaagagtc gtttcaacca
    60301 aaaagtctgc ctcagggcta ctgactccaa tttcttttaa atgtaaatgc gcttgactga
    60361 ggatttgtcc cagtccttca gcatcttttt gtgaaatcgc aacttctgct tgctgggtta
    60421 attctcccaa ggcatgcaaa aacggtaggg catccttgcc cttattttga accacttgga
    60481 tggcttcacg agtatgacca taaacacccg tatcggcaat caccaaatag gcggataaat
    60541 ccatctcaag ttctgtaaat cctacgttct tgataaagcg aataggttgg tcactgagac
    60601 aggtcttagc atccaaacca ctaggattca tatgggcaat catttcagct cgattgacca
    60661 agatttctag tacatcatga ggcagatcag cctgatagta gtcaaatacc gcacgaatgg
    60721 ccgctatgct gatagccgct gacgaaccca tcccccgttt ctcagggata gccgagtcaa
    60781 tctcacaacg aatgcaggct tctgtgatat ccaaatactc cagtgaggca taaaccgcca
    60841 tggacaaggt atcctcctca taaaggcgcc aaggactctc tgcaggaact accttacagg
    60901 tcacctccac ctccaaaaga ggcagggaaa tggcaggata accgtaaacg accgcatgtt
    60961 cccctattaa aattatctta ctatgtgcct gaccgacacc aacttttttt gtcatttttt
    61021 ccttttacta gacgaaaaaa cgtcttattt ttcatacaag tattaattct ttcctatcta
    61081 ttttattata ttttcacaaa aaaagcgatt gtttccattc acaatcgctt ctttcattac
    61141 cgaacccatt caccattata attgacagaa tagccatcta caatcgtatt cactgccaag
    61201 gcacctgagc tataagcgta gtaccatctg ccattgacct ggaaccaacc tgtcgtcata
    61261 gaacgatgaa agaaactcca taccattaag taaagaggaa agtcatgagg gagcatgcgt
    61321 cattgacaac ctattttagt gacgtacaaa gtttcattaa caagtactcg tttcggccat
    61381 ttataggtgc ggtgtttgca gaaatagggt tcaatcttcg cccattcttg atcgtttaaa
    61441 tcagtatcat atgctttgcg tgtcataact ctagtttaac atttttttgt gaatacaggt
    61501 tctaaataat cgaccacgaa aatttcttaa gtggaaaacg ccttatgaag tatgctacgg
    61561 gaaacttatg cacttaattt gacaactcaa tatgtaaaaa tatatactat a
//
LOCUS       DAVBNN010000006        59124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBNN010000006 DAVBNN010000000
VERSION     DAVBNN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.006"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..170
                     /locus_tag="VQ847_000342"
     CDS             <1..170
                     /locus_tag="VQ847_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3049745.1"
                     /translation="EQVLKEIRKRGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIVN
                     RRWTRMLFESR"
     gene            complement(287..634)
                     /locus_tag="VQ847_000343"
     CDS             complement(287..634)
                     /locus_tag="VQ847_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3049746.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(745..2520)
                     /gene="spxB"
                     /locus_tag="VQ847_000344"
     CDS             complement(745..2520)
                     /gene="spxB"
                     /locus_tag="VQ847_000344"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3049747.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2727..4970)
                     /locus_tag="VQ847_000345"
     CDS             complement(2727..4970)
                     /locus_tag="VQ847_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3049748.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4980..5351)
                     /locus_tag="VQ847_000346"
     CDS             complement(4980..5351)
                     /locus_tag="VQ847_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3049749.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5362..5757)
                     /locus_tag="VQ847_000347"
     CDS             complement(5362..5757)
                     /locus_tag="VQ847_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3049750.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5941..6039
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6123..6914
                     /gene="thiD"
                     /locus_tag="VQ847_000348"
     CDS             6123..6914
                     /gene="thiD"
                     /locus_tag="VQ847_000348"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3049751.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7123..7755)
                     /locus_tag="VQ847_000349"
     CDS             complement(7123..7755)
                     /locus_tag="VQ847_000349"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3049752.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7748..8551)
                     /locus_tag="VQ847_000350"
     CDS             complement(7748..8551)
                     /locus_tag="VQ847_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3049753.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8551..9075)
                     /gene="thiW"
                     /locus_tag="VQ847_000351"
     CDS             complement(8551..9075)
                     /gene="thiW"
                     /locus_tag="VQ847_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3049754.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9080..9772)
                     /gene="tenA"
                     /locus_tag="VQ847_000352"
     CDS             complement(9080..9772)
                     /gene="tenA"
                     /locus_tag="VQ847_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3049755.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9783..10433)
                     /locus_tag="VQ847_000353"
     CDS             complement(9783..10433)
                     /locus_tag="VQ847_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3049756.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10435..11820)
                     /locus_tag="VQ847_000354"
     CDS             complement(10435..11820)
                     /locus_tag="VQ847_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049757.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHVQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQRCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11821..12381)
                     /locus_tag="VQ847_000355"
     CDS             complement(11821..12381)
                     /locus_tag="VQ847_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3049758.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12644..12732)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12941..13570)
                     /locus_tag="VQ847_000356"
     CDS             complement(12941..13570)
                     /locus_tag="VQ847_000356"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3049759.1"
                     /translation="MFHKELLKLYFICGTTTCQGKDLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13572..14354)
                     /gene="thiM"
                     /locus_tag="VQ847_000357"
     CDS             complement(13572..14354)
                     /gene="thiM"
                     /locus_tag="VQ847_000357"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3049760.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLAY
                     NIAGEIAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(14765..15304)
                     /locus_tag="VQ847_000358"
     CDS             complement(14765..15304)
                     /locus_tag="VQ847_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3049761.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(15519..15607)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15861..16997)
                     /gene="lctO"
                     /locus_tag="VQ847_000359"
     CDS             complement(15861..16997)
                     /gene="lctO"
                     /locus_tag="VQ847_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3049762.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17623..19113)
                     /gene="lysS"
                     /locus_tag="VQ847_000360"
     CDS             complement(17623..19113)
                     /gene="lysS"
                     /locus_tag="VQ847_000360"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3049763.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19241..19387)
                     /locus_tag="VQ847_000361"
     CDS             complement(19241..19387)
                     /locus_tag="VQ847_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3049764.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            19614..20282
                     /locus_tag="VQ847_000362"
     CDS             19614..20282
                     /locus_tag="VQ847_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3049765.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTCHAGFGNPST
                     LSRK"
     gene            20242..20622
                     /locus_tag="VQ847_000363"
     CDS             20242..20622
                     /locus_tag="VQ847_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3049766.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            20632..20919
                     /locus_tag="VQ847_000364"
     CDS             20632..20919
                     /locus_tag="VQ847_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3049767.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            20920..21683
                     /locus_tag="VQ847_000365"
                     /pseudo
     CDS             20920..21683
                     /locus_tag="VQ847_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21695..22561
                     /locus_tag="VQ847_000366"
     CDS             21695..22561
                     /locus_tag="VQ847_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3049768.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(22648..23295)
                     /locus_tag="VQ847_000367"
     CDS             complement(22648..23295)
                     /locus_tag="VQ847_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049769.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23292..23990)
                     /locus_tag="VQ847_000368"
     CDS             complement(23292..23990)
                     /locus_tag="VQ847_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049770.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(24000..24752)
                     /locus_tag="VQ847_000369"
     CDS             complement(24000..24752)
                     /locus_tag="VQ847_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049771.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24752..25516)
                     /locus_tag="VQ847_000370"
     CDS             complement(24752..25516)
                     /locus_tag="VQ847_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049772.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25612..26015)
                     /locus_tag="VQ847_000371"
                     /pseudo
     CDS             complement(25612..26015)
                     /locus_tag="VQ847_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26195..26827)
                     /locus_tag="VQ847_000372"
     CDS             complement(26195..26827)
                     /locus_tag="VQ847_000372"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3049773.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26861..27562)
                     /gene="pyrF"
                     /locus_tag="VQ847_000373"
     CDS             complement(26861..27562)
                     /gene="pyrF"
                     /locus_tag="VQ847_000373"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3049774.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27795..28994)
                     /gene="divIB"
                     /locus_tag="VQ847_000374"
     CDS             complement(27795..28994)
                     /gene="divIB"
                     /locus_tag="VQ847_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3049775.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29004..30062)
                     /locus_tag="VQ847_000375"
     CDS             complement(29004..30062)
                     /locus_tag="VQ847_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3049776.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30064..31416)
                     /locus_tag="VQ847_000376"
     CDS             complement(30064..31416)
                     /locus_tag="VQ847_000376"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3049777.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31520..32161)
                     /locus_tag="VQ847_000377"
     CDS             complement(31520..32161)
                     /locus_tag="VQ847_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049778.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTRGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32163..34183)
                     /locus_tag="VQ847_000378"
                     /pseudo
     CDS             complement(32163..34183)
                     /locus_tag="VQ847_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34254..34553)
                     /locus_tag="VQ847_000379"
     CDS             complement(34254..34553)
                     /locus_tag="VQ847_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3049779.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(34919..35173)
                     /locus_tag="VQ847_000380"
     CDS             complement(34919..35173)
                     /locus_tag="VQ847_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3049780.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35193..37034)
                     /gene="typA"
                     /locus_tag="VQ847_000381"
     CDS             complement(35193..37034)
                     /gene="typA"
                     /locus_tag="VQ847_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3049781.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37196..37921
                     /locus_tag="VQ847_000382"
     CDS             37196..37921
                     /locus_tag="VQ847_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3049782.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(37961..38188)
                     /locus_tag="VQ847_000383"
     CDS             complement(37961..38188)
                     /locus_tag="VQ847_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049783.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38277..38657)
                     /locus_tag="VQ847_000384"
     CDS             complement(38277..38657)
                     /locus_tag="VQ847_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3049784.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(38657..38926)
                     /locus_tag="VQ847_000385"
     CDS             complement(38657..38926)
                     /locus_tag="VQ847_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3049785.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            38990..39898
                     /locus_tag="VQ847_000386"
     CDS             38990..39898
                     /locus_tag="VQ847_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3049786.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(39952..40707)
                     /locus_tag="VQ847_000387"
     CDS             complement(39952..40707)
                     /locus_tag="VQ847_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3049787.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40728..41657)
                     /locus_tag="VQ847_000388"
     CDS             complement(40728..41657)
                     /locus_tag="VQ847_000388"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3049788.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(41672..42295)
                     /locus_tag="VQ847_000389"
     CDS             complement(41672..42295)
                     /locus_tag="VQ847_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3049789.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42288..43526)
                     /gene="hflX"
                     /locus_tag="VQ847_000390"
     CDS             complement(42288..43526)
                     /gene="hflX"
                     /locus_tag="VQ847_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3049790.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(43519..44403)
                     /gene="miaA"
                     /locus_tag="VQ847_000391"
     CDS             complement(43519..44403)
                     /gene="miaA"
                     /locus_tag="VQ847_000391"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3049791.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIVGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            44524..44694
                     /locus_tag="VQ847_000392"
     CDS             44524..44694
                     /locus_tag="VQ847_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3049792.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(44742..45581)
                     /locus_tag="VQ847_000393"
     CDS             complement(44742..45581)
                     /locus_tag="VQ847_000393"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3049793.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45678..46637)
                     /locus_tag="VQ847_000394"
     CDS             complement(45678..46637)
                     /locus_tag="VQ847_000394"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3049794.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(46764..47761)
                     /locus_tag="VQ847_000395"
                     /pseudo
     CDS             complement(46764..47761)
                     /locus_tag="VQ847_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(47811..48428)
                     /locus_tag="VQ847_000396"
     CDS             complement(47811..48428)
                     /locus_tag="VQ847_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3049795.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48429..50150)
                     /gene="pabB"
                     /locus_tag="VQ847_000397"
     CDS             complement(48429..50150)
                     /gene="pabB"
                     /locus_tag="VQ847_000397"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3049796.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50211..55853)
                     /locus_tag="VQ847_000398"
     CDS             complement(50211..55853)
                     /locus_tag="VQ847_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3049797.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(55875..56438)
                     /locus_tag="VQ847_000399"
     CDS             complement(55875..56438)
                     /locus_tag="VQ847_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3049798.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(56554..58245)
                     /locus_tag="VQ847_000400"
     CDS             complement(56554..58245)
                     /locus_tag="VQ847_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3049799.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58242..58979)
                     /locus_tag="VQ847_000401"
     CDS             complement(58242..58979)
                     /locus_tag="VQ847_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3049800.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17503 a        12985 c        10674 g        17962 t
ORIGIN      
        1 ttgaacaagt gttgaaagag attcgtaaac gtggatttaa gaataaagcc tttcgaactt
       61 tggaagatgt catgaatcaa cttcaagatg tcatacaagg actggagaag gaggtgataa
      121 agtccatcgt taatcggaga tggactagaa tgctttttga aagcagatga gtattatatg
      181 caatttcttt atataaaaag accggattgc tccgatcttt caatagttca tattctcaat
      241 ttctatttta aaaatagcta aggttaacgt caaatgacta cgcgacctat ttcatacgat
      301 aaaaatcaag cactagacca gcaggtcctt gaactaataa ggactctgtt ccccaatcgg
      361 ttacagttgg tccgtgtaaa acctttatac caagctcgtt caaccgtttg tagttctggt
      421 ctacatcctc aacctcgata tgaataatga ttcctgactg aaagttttcc aaaggaacca
      481 aatgattttg tgacaacata aggcagtgac taccaatcgt aaactgagca aaaccatcat
      541 cagcataatc tgccttttta tccaagatat gctccaagtc agcacagact tggggaacat
      601 ttgaaacgat aatatctaat tgatttaaat tcatttactc tcctccataa aaagaccgga
      661 ttgctccgat cttttaaagt tctgctctat gaaaatcaaa gaataaagtc tacaagtttc
      721 atatttgatt ttcggcgaga ggaattattt aattgcgcgt gattgcaatc cttcttcttc
      781 caagaagaga cggaatggta cgagttcttc tgcttcgtat ttttccttga aggctttgat
      841 agcttcttct gagtgaagtt ttggatccaa ttcaagtact tctactggaa gtggacggtg
      901 ttgagtgatg cgagcatcga tgacaacagt tttaccttct ttgttcaatt taacagcttc
      961 tgcaacaact gcatcgatgt cttcgatacg gtcaactgtg aatccaacag ctccttgagc
     1021 ttccgcaatt ttagcgtagt cagcgtttgt gaagtctaca ccaaacaagt gtttgtttgt
     1081 atcttcgtat ttgttcttga tgaagccgta ctcagcattt gagaagacaa ggttgataac
     1141 tggaaggtcg tattgaacgt ttgtgataac gtctgggtag cacatgttga atgctccgtc
     1201 acccatgatg ttccatactt ggcgatctgg attgtctttc ttagcagcga taccaccagg
     1261 aagggcaata cccattgtcg caaagagtgg agatgtacgc cacatgttct taggtgtcat
     1321 gtgaaggtga cgagtagatg tttgagtagt gttacctacg tcgattgagt agatagcgtc
     1381 ttgatcagca tgtttgttga ttgcattgta aacttgatac aattgcaatt caccctcagt
     1441 tttaccttcg agtttgttca tgtaatcacg ccagttttga ttgttcttaa cgtttgcacg
     1501 ccaccatgga gttgattcaa ctgggtttac tttgtcaagg atagctttag ctgcttgacc
     1561 agcatcacca aggattgaag cgtcaagggc atgacgttta ccaagtttgt aagggtcgat
     1621 atcgacttgg atgaattttt cagtgttctt gaatgcttcg taaacttcag cgaatgggaa
     1681 gtttgaacca aggaaaagaa ctgtgtctgc ttcaaagacc acttcgttgg ctggtttcca
     1741 accaacacgg taagcagaac ctgtcaaacc ttcatagttc cattcgaaag cttcaaagtt
     1801 tttaccagtt gtgatgattg gtgctttgat tttacgtgac aattcagtaa tcacttcacc
     1861 agctttaaca ccaccaaatc cagcatagat aactgggcgt tcagcattgt tcaagatttc
     1921 aacagctttg tcgatttcaa cttcgttcaa agcaggagcg atgaatgagc gttcgtatga
     1981 acctgaaccg tagtatgagt tttcatcgat ttcttggaaa ccgaagttta ctggaatttc
     2041 aacaacagct ggaccttttt tagaaactgc agcacggcag gcttcgtcaa ttacttttgg
     2101 caattgctca gcgtaagcta cacgtttgtt gtaaacagcg ataccgttgt acattgggtt
     2161 ttggttaagc tcttggaaag catccatgtt caattcgtta actggacgtg atccaaggat
     2221 cgctaggaat ggagtgttat ccatagctgc atcgtaaaca ccgttaatca agtgagtcgc
     2281 acctggacca cctgaaccaa ctgcaacccc gattgagccg ccgaatttag cttgcataac
     2341 cgctgcaaga gcacctgtct cttcgtggcg aacttgtaag aaacggatat ctttgtcttc
     2401 agccaaagca tccatcaatg agctgagtgt tcctgatggg ataccgtaga ttgtatctac
     2461 gccccatgtt ttcaatacgt taagcattgc tgcagatgca gtaattttcc cttgagtcat
     2521 aatgataact ctccttcaat ttttttaaac ttggagaata cgattacata gaattggaaa
     2581 cgttctccaa atttttacta ttccactgta tcatatttat gctgactttt ctaaaaatct
     2641 gctcaaaact ctctattctc tattctaata cagttttgaa agtgttgtca tttctgtttt
     2701 ataacaaaga aatctagtca ttacttttag tctattttac taaaatttaa cagaagggaa
     2761 ctggtcagaa cagatacaga actaaaggcc atggctagac ctgccaattc tgggttgaga
     2821 gccagtccaa cacctgaaaa gactcctgct gcaatcggaa ttccgacaac attgtagata
     2881 aaagcccaga aaagattgag tagaattcga tgaaaggttt tcttactcat atcaaaggca
     2941 cgaaccactc ctaaaagatt attggttgtc aacaccaaat ctgctgactc gatggcgata
     3001 tctgttccag ctcccatagc aatccccaca tctgctacac taagggcagg agcgtcattg
     3061 ataccgtccc caacaaaggc tactttccct gactgttgca gtttatggat ttcatgggct
     3121 ttttcttctg gcaagacgcc tgcaatgacc tcttcaattc cgatttgatc tgcaatagca
     3181 cgcgccacac cagcattgtc tcctgtcagc atgactgttc ggagaccacg tttttttagc
     3241 tgactgatga ctagcttagc attttcctta ggaatatctt gcaaagcaag caagcctttg
     3301 atttcattgt caacagctaa gaacacaact gtcttagctt ctttttctag ttcttctagt
     3361 ttatcttgat aagtattaga aatatccatg ccatccagca ttttagcatt tccaagtaaa
     3421 acttgttttc cattgattcg ccctgaaaca cctttcccgt gcaaggcctg aaaattttca
     3481 acagtttgaa actcaagtcc agcttcactc gctcgcttaa cgatagcctc agccagtggg
     3541 tgttgagaag catcttccaa ggaggctgcc aatccaaaca cttctacttc gtcgccgatg
     3601 atatctgtta ccacaggttt cccttccgtc aaagtcccgg tcttatcaaa gacaagagtt
     3661 tgaactttct ggatttcctg taagacagtt ccatttttga ggagaacccc catcttggca
     3721 ctacgtcctg tccccaccat aagggctgtc ggtgttgcaa gtcccaaggc acaaggacag
     3781 gcgataatca aaaccgccac tccgtagaga agagaggaca caaagctagc tccaagcacg
     3841 accacactat ccctgagcaa gacgaaccaa acccaaaagg tcatgattcc taaaatgaca
     3901 actactggga caaaaatccc tgaaatctta tccgtcaagt cctgaatcgg cgcacgactt
     3961 gtctgagctt tcttcacaaa atccacaatc tgagccaaaa cagtctctga gccaactttt
     4021 tctgctctaa agacaagcgt tccactatga ttgatggttg agccaatgac agtatctcca
     4081 actgtcttgt ccacaggcag actctcacct gtcaccatgg attcgtcaat actagagaca
     4141 ccttctacta cgacaccatc aacagcaatc ttttcaccgg gacgcactcg aatcaggtcg
     4201 cctaccttga cttgttccaa aggaacttgg acataactat catcactcaa gacttctgcg
     4261 gttttagctt gcaagtccag taatttctcc acagcttggg acgtattttt tctcattttt
     4321 tcctcaaaaa ctgctcccaa aagaacgaaa aagaggataa atccagcact ttcgaagtaa
     4381 acagggagac cagcaaagag agcaactagg ctatagaaat aagccactag agttcccagc
     4441 gcaaccaagg tatccatgtt ggcattgtgc tttttaaaac tggcccaagc actctggata
     4501 tatggcttac ctgcaactaa cataataggc gttgttgcta gaaaggttcc ccaatgcatg
     4561 acttgatgac taatgctacc tgtcaacatc ccaatcatga gaatcacaag aggcacagta
     4621 aagatactag taatccaaaa acgttgcagg agagatagag attttcgagt cttctcaacg
     4681 actatatagc ttcccttttg catcttcatg ccacaagaaa attcatgtcg ccctaattct
     4741 tgaggtgtaa aacgaatgac tttctcctca tctacgccga ttggttccaa gataccttct
     4801 tcttcaaaca gaatttcctt ataacagttt gaaggagtag cacgatgaaa ggtaatctca
     4861 gctggaattc ccttttgaag ctggatatgg gctggatgat agcctttttc agctcggata
     4921 cggatttttt gaatgccatt ttctaagctt gctttcacaa tttctgtcat agtctccacc
     4981 tactctacaa tcatcttgcc gtgcatcatg ttcataccac aagcaaagcc aaactctcca
     5041 acctgctcag gcgtgatttc cactacatac tcttccccca ttggcaggtt cgcatgtaca
     5101 ccaaaatctg gaaaaacaat ttgatccaga catggtgaag gatccttgcg gtcaaagaca
     5161 atgcgtgctg gcactgattt cttgaggaca atcaactcag gagtatagcc tcccatgact
     5221 tccactcgaa tctcttggta tccgtttttt tgctgggctt tttgtccaga tttttcaggc
     5281 tttttgaaaa accaaaacaa gataaacgcg ataagggcaa tacaaataat ggttacaata
     5341 ctatttaaca tggcgtctcc tttacataca attacatctt acttctgtta cagcacttga
     5401 tttcttctct gaaatcacag cttccaagtc ttccaagtca gtctgagtaa attcacattc
     5461 tacaatcaag tcagccaaca aattcctaat cctacgggaa caaaccttgt ctttgatatc
     5521 ttggacaagt aaatcccgac tttggtctag agttaaaagc gctgaataaa caaaggactt
     5581 gccttctttt ttccgagtca gacactcttt ctcaaccaaa cgagccaaaa gagtttgaat
     5641 ggtcgacttg gaccagtcga accgctctgc caaaacccta atcaaatctg tactggtctg
     5701 ctccccctgc atccaaataa tcttcatgac ctgccattct gcatctgaaa tctgcattac
     5761 catacctcca aaatctacat ttgtcaatta cactcatcag tatactctta aaatctacat
     5821 ttgtcaatta tagaaataat attttcttcg aaaaatagaa ttttaatcat ttgaaaaacg
     5881 atttgcagtc aaatattact atataaacaa taaaaatatg ctatactaaa gaaaaaagaa
     5941 aacaaccact aggggtgcgt aaagctgaga ttaacgactg ttagatccct ctgactcaat
     6001 ctaggtaatg ctagctgatg gaagtggaaa tgataatggg gactagcagt cttctattgc
     6061 ctttctaaaa cagactagct tgttcttaag aatacaaact tcagttggtt gggaggtttt
     6121 agatgactta tttacccgtt gctttgacca ttgcagggac tgaccctagt ggtggtgctg
     6181 gcattatggc agatttaaag tcattccaag cgagagatgt ctatggaatg gctgttgtaa
     6241 ccagtcttgt cgctcaaaat accagaggtg ttcagctaat cgagcacgtt tctcctcaaa
     6301 tgttgaaagc ccaattggag agtgtctttt ctgatattcc acctcaggct gtaaaaactg
     6361 gaatgttggc tactactgaa atcatggaaa tcatccaacc ctatcttaaa aaactggatt
     6421 gtccctatgt ccttgatcct gttatggttg ctacaagtgg agatgccttg attgactcaa
     6481 gtgctagaga ctatctcaaa acaaacttac tacctctagc aactattatt acgccaaatc
     6541 ttcctgaagc agaagagatt gttggttttt caatccatga ccccgaaggc atgcagcgtg
     6601 ctggtcgcct gattttaaaa gaatttggtc ctcagtctgt ggttatcaaa ggcggacatc
     6661 tcaaaggtgg tgctaaagat ttcctcttta ccaagaatga acaatttgtc tgggaaagcc
     6721 cacgaattca aacctgtcac acccatggta ctggatgtac ctttgctgca gtgattactg
     6781 ctgaactagc caagggcaag agtctttacc aggcagttga taaggccaag gcctttatca
     6841 caaaagctat tcaagatgcc cctcaactcg gtcatggttc tggtccagtc aaccatacaa
     6901 cttttaaaga ttaagaaaaa aactctctag ttcccacttt aagggaatta gagagttttt
     6961 atactcttcg aaaatctctt caaactacgt cagcttccat ctgcaacctc aaaacactgt
     7021 tttgagctga cttcgtcagt cttatctaaa acctcaaggc agtactttga gcaacctgcg
     7081 actagctttc tagtttactc tttgattttc attgagtatt aattaggaaa gaatgtcatg
     7141 caactttgtt aaaaaggctt gcgtttttgc ctcaatatct tctgcttgca tcaaatcacg
     7201 tacaacagct acaccagcta tgccagtgcc cataagctga tcaatattct ccgaagtcaa
     7261 gcctccaata gcaactactg gaatggcaac cgtttggcaa attgttttca aggtcgatat
     7321 cagagtaatg ggcgcatttt ccttggtggt ggttgggaaa atggctcctg tacccaagta
     7381 atctgcacct gatttctccg cttccagagc tcttttaacc gttttagcgg tgacaccgag
     7441 gattttttca ggacccaaga ctttgcgagc taccgaaact ggtaattcat catctccgat
     7501 atgcagacct gctgcatcaa ccgcaagaca aacatccaac cgatcatcga ttatcaaggg
     7561 gacctgatag gcatctgtta tttccttgac ttgttttgcc agttgataat attgattggt
     7621 tgtgagattt ttttctcgca attggactat ggtaacccct gaacggcagg ccgtctcaac
     7681 ttttgcaaga aagctttcca cggaatcttg atagcgattg gttaccagat atagtctaag
     7741 tgcttctcta ttcataaacc tctcctttga tggtatctag ccaattttca tctcttctta
     7801 ggagcgaaag ctgattgagt acttggtaac gaaattcttc caatcccatt ccttgaacaa
     7861 ctattttctc agcagcgata ttgagataag agactgctaa gcaagaagct tcaaaaccag
     7921 tctttccttg gctgagaaaa acggctgtta aggctccaac caagtctcct gtccctgtta
     7981 tccagtctaa ttcagtacag ccattctcca gtacagcaac ttgattctcc gaaacaataa
     8041 ggtccttggg gccagtaact aagaaagaca taccaggata ggtctgacac cagtctttca
     8101 agacttgaag caaatcctcc gtttcttgat ctttagcact cgcatcgacc ccaacgccgt
     8161 ggtgctttaa tccaacaaga cttcgaattt ctgacatgtt tcctttaagg accgtaggtc
     8221 tatagtctaa aaggtcttta actaagctct tacgaatgga tgaagtcgtt acgccaaccg
     8281 catctactac catcgggaga gaagattggt ttgcatacga agctgccatg cggattgctt
     8341 tttccttctc agctgacaaa tgccccaaat tgatgaagag agcctgactt tgcttagtaa
     8401 aatcaagaac ttcacgggga tcatctgcca tgacaggttt gcatcccaga gccaaaatcc
     8461 catttgccag catctcacaa gaaatctcat tggtcataca gtgaatgagg gaactagagc
     8521 ctataggaaa aggatttgtc aatgcctgca tcattctatc ctttcagcaa agaaatatcc
     8581 ttgcactttt ttaaagaatt cctgcttgat taaaaatcta aatgcaataa aggaaatcgc
     8641 tgtaccaatc aaggttgctc cgaaaaatcg aggagtgtag ataaaccaac taagcttagc
     8701 agccgatcct gtaaagagca ccataacagg ataggaaaca atagaaccaa taatacctgt
     8761 tcccacaatt tctcccaagg cagaaaagta aaattttcga ccgtacttat aaaagagacc
     8821 tgctagaagg gctccaaaag tcgctcctgt gagagctaaa ggcggaatcc cttgagtcgt
     8881 catacggata aaggctgtca ctgtagccat agccaaggca taaacaggtc ccatcatgat
     8941 tcccgctaga atattgacta cactggacat cggtgccatt ccctcaatcc gaaagatagg
     9001 tgtaaggact acatcaaggg caatcatcat agataaaatg gtcaatttgt gaacttgtag
     9061 ttggtgcttt ctcatgtttc tattcttctc ctttttctaa agactgtaaa tcgctcttcc
     9121 atgtctggtg ttggtaagcc atctcccaaa acttagcttc catatgaaca ctgatgtgga
     9181 aggcatctag cattttttgc ttatctgtct catcactttc tcgataaagc tgattgacca
     9241 gtgctccctc ctctctgatc tgttgctcta actcatccgt aatataagtt tcaatccatt
     9301 gttgatagag aggatttggt gatggtttaa gattaagtga tttgcctata tcatggtata
     9361 accaaggaca aggaagcaag cttgcaaaag ctatggctaa gttcggttct gcaaattgcc
     9421 tataaatatg agaaatgtaa tgataacagg ttggagcgat tggatgttgc tccatttcct
     9481 ggtcgttgat ttccaattcc ttgaaaaatt gttggcgaat aaataactca ccctccacta
     9541 aaccctgagc attttgtttc aagagtcttt tcatctcttg gtttgaagtc ttatcagcca
     9601 aaagatgata gatttctgag aaagccttca gatagtaggc atcctgaatc aggtaatagc
     9661 ggaaaatggc aggttctaaa ttcccctctt gtaattgtaa aataaaggga tgatgaaagg
     9721 aagcctgcca agctttcttg gataattcca tcgcaatatc tgtaaattcc ataataactc
     9781 ctttataaaa atagactggt ttgaagcaat aaaaagaaaa gcaggtagat taattttgtt
     9841 tttttaggaa tataaaaagt ccgatagcta ttcttcaact gtgcatgttc gtcatatccg
     9901 tgagcagata gagctctcag gtaaagatgg cgccacctaa agactgtcat cagaacctta
     9961 ctgtaaatca agggcgacca aaaatgtagt tcttgaccac gtaataggca agcttctttg
    10021 agggacttga tttcttgctg aatgagagga aaagaattga ataccacaat caaggcatag
    10081 gaccaagagc gtgatagccc cttttgagcc aagtacaaga gaagctcttt tagtgaaata
    10141 gaggaaacaa agacaaggcc gatacaaact gtcacaaagg ccctcgttcc aagcatgact
    10201 gcctgtgaag catctccgtg taactgaact gcccagtagt tggcaaaaga tggtaaaatg
    10261 gcaagtatga tcatccaagc taacatttta aatcgacggt aatagagcat aaagagaata
    10321 caaaatgcga ctaccgaaag attcagagca atcgaaggaa tgaaagatgt ttccaaggat
    10381 aaaatcagca agaagagact gataatcggt gtctgggttg ctactttgac catactatct
    10441 cacctcccct tgggtattgc tactctgaga tgtaagtggt ttggtaatgg tcacttcttt
    10501 cacatgccga agaccctgac tagtcatctc aatccaataa tcaaccacag aaatcaaagg
    10561 gtctaaacga tgactaatga gcagaaaact tcttccttga ttcctctcct ccacaatcca
    10621 cttgcaaaaa taatggcagg ctctatcatc caaacctgca aaaggttcat ctagcaagat
    10681 cacggaagcc ttactggtca agatggtcag gagctgaaga attttttgct gaccaccact
    10741 taattgatag ggactcttat cgactgcctg ctccaaatca aaatatcgta aagcttgaaa
    10801 aatccgctga tttctttcag aatcaggtcc atctaattga agctcctctc gcagactgac
    10861 tcggataaac tgcttctcag cttcctgaac aacacccgtc agatcacggt acaaactctt
    10921 tttctttttc aggactgtcc ccttccatgc aatgcgcccc ttatactttt gaaattgaag
    10981 aatagagcga aagagggttg atttcccgac accattgtca cccaggatac aggaaatccc
    11041 ttgatagaat gtgaaatcag caattgaaaa gagggggcga ttaccaagct caccagtcac
    11101 acggttcata tggaataatt ccgggctagc agcaacttcc tttgaagcaa cctgtgtcat
    11161 ctcataggaa gggatttgaa acacttccct tagttttccg tctcttagct caaccatatg
    11221 gtcgatatag gctttatagt cagataaatc atggtcgcac aaaataactg tcttcccatc
    11281 aagagccaac tcttttagaa tctccaatat ctcgattctg ctcttgcggt caatggaagc
    11341 gaagggctca tccaagagat ataccctagg attcatggca aagaggacag ccagcgctgc
    11401 tttttgcttt tccccacccg ataggtgatg aatgggacgg tgtaagattg cctcgcaacg
    11461 acatcgctgg acaacctctg ctattttaga atcaatttcc tgaaggtgat agccgatatt
    11521 ctccaaggtg aaaatcagct cctcaaacaa gttctccatg gtaaattgat gattgggatt
    11581 ttgaaagaga atgccaacct tctggacacg ttcgacgata gaaagctgac tgacctcact
    11641 cccatctatc aggacttgac cgctataggg aagagaacta acttgggcaa tcatttgaaa
    11701 gaggcttgat tttccagacc cactactccc aactaacaag gtaaaggctt gcacatgaaa
    11761 agtaaaatca aacggctcag agaagattgg ggactgaatc gctcgtagtt ccagacccat
    11821 ctatgctttt cctccagttg caaactgatg atagagtttg acaatggcac gaaccaagat
    11881 ggtacagaag aaataaacag aaataaaacg taccacaagc aaggaaagga caaacggaag
    11941 ggaaaaggcg tagtaaccta acttaatgta ttcatagaca aagctaacaa gcgtaatccc
    12001 aatactatta gcagttagag agagccaact ttcatagcga ttcttagtta cgataaaacc
    12061 aaattcactt cccaaacctt gaaccaagcc agacaaaaga gctcctagac caaattggct
    12121 accataaagg acttcagcaa gcgcagctag cacttctcca atcgttgcac ttccgactct
    12181 cggaacaaag atggcagcaa tgggcgcagc catacaccag agaccgaaga ggatttcatt
    12241 ggcaaaggcc tgcaaaccaa gaggtgttaa gagtagactg agaatattat acacatatcc
    12301 tgaaccaacg aaaaccccac caaaaaagat agacaagaaa gcaagcaaga taacatcttt
    12361 taactgccat tttttcaaca taaaaaactc ctttttttta aagaaaagtg gggcactcaa
    12421 gaagaccgac ctaaatactt tgtatagcag actgaattta gaacagtaca caagaatgct
    12481 aaaatatttc tagaaattaa tttgaatttt ctaattgatt tgttcgcatc ttatttcaat
    12541 ctactatatc atcttcatcc agtttcgtaa aagaaaaaac tctaattaca gatacgaatt
    12601 agagttcagc ttacaagatt agacagttct tttcgacata cgaaaaaaac atttcacatt
    12661 tcccttcgcc agtcttaact gtatcaggtt caatgggtat catctcagcc taaagcaccc
    12721 caaatgtctc tattatttaa ttatgtgatt attataacac acattttata ctagttcaag
    12781 aaattgaact ggaaatacag ccttgcactc acaaagacag cagatctttc ttttgcaaaa
    12841 aacaaatgac ctgtttgatg aattagccat tcaagctgaa tctggacata gctttttaaa
    12901 aaaggaaaat cctacttact tagaatccaa ggatagatat ctattgttca ctcatttccc
    12961 gaacagtttt ttctatattt tttgcatacg atattgccga aatgattgaa acgccatcca
    13021 tattggtctt tataatgtct ttaatatgtt tcgtctgtat cccaccaatt gcaactaaag
    13081 gcatttgtgg caatagtttt ctcatcaatt caagaccttc ataacctata gtaccaccag
    13141 catcatcctt tgactgggta ccaaatacag gcccaacacc tacataatct acatattcaa
    13201 cttttgattg ttgaaattct tcctcgtttt ttatagaaag accaattatt ttatctggca
    13261 tcaattttct aatttcatca acaccaatat catcttgacc tacatgtacg ccatcagcgt
    13321 caatttccat tgccaaatcg atatcatcat taacgataaa cggcacattg tattttttac
    13381 aaagttcttt aatttggata gctagctcaa gtttttctaa gccttctaaa gcaccctcac
    13441 ctttttctcg aaattgaaat aaggttatac caccttttaa ggcttcctca acgactgtat
    13501 atagatcttt tccttggcaa gtagtcgttc cacaaataaa atatagtttt agtaattctt
    13561 tatgaaacat cttacttcac tcttttgaat ttcttgacat cttcatctgt aatttcatat
    13621 aaggcattta taaattcaac tttaaatgtt ccaggaagat gtccattggg acgtttttct
    13681 gctatttctc cagcgatatt gtaagccaac attgctgttt ctaatgattt caattcttga
    13741 cctttttcaa gtccgataaa gcttgctact acagctccta ataagcatcc tgtcccaatg
    13801 actttcggca tcatagcact accattatga atcgttacca cttctccatt aacagcaatg
    13861 gcatccactt cacctgttac tactattgga atattgaact tctcatttgc tgctagagca
    13921 atttcgtcaa tattatctac gcccgcacta tctactcctt tagatgccac atctattcct
    13981 actaaagagg caatctcgcc agcatttcct ctaatcgctg ctagtttata attgttgatt
    14041 agatcatctg ctactttttt tctatattct cctgctccac aggctacagg atctaaaact
    14101 gctgggacat tatatttctc tgcaattttc agagcagctt ggtataattt ccaattttca
    14161 tctgtcaatg ttcctatgtt tattaataaa ccaccagcat actttaataa gtcctctaaa
    14221 tctgctggaa actcactcat ggctggtgag gcgcccagtg ctactaatcc atttgctgtg
    14281 aaatttttta ctacatcatt ggtgatgcaa atgaccaaag gtgctttttc ttttaataat
    14341 tttaaacttg tcatattgaa atccttcctt ttcactttat acgatctact aatttcgatt
    14401 tatctttagt tgagaatttt tttcatttac attgaatgat ttatactcaa tgaaaatcaa
    14461 agagcaaact aggaggctaa ccgcaggttg ctcaaaacac tgctttgagc ctgtagataa
    14521 gactgacgaa gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgtggtttg
    14581 aagagatttt cgaagagtct tacctcatca aatttgtaaa tatcatgagc cttctctaga
    14641 catcgtaacc aatatcaaaa aaagctaatt ctaaagcgac tgcttgattc cagcgttgct
    14701 gaagttctgt caaatcttct cgatttttac cgacacgatt gagttcatca accagaaatt
    14761 gaactcactc tgcaaagaaa ggacctctgt ggagattgat ccattccgaa tgaatataga
    14821 cttcaggtag agccaaatct ttagaacccc agtctaaata gagaccttct gcaatgacca
    14881 gcataaccaa aagatgggca tagtctgatg aagccactgc ccaatacatt agatcctgaa
    14941 aggcttttgt tacagggtgc aaagtcactt ctagatagtt attctctgct acttttaact
    15001 ctttaaaagc cttttggaaa taaccatctt catctgcttc aagaaagcct agttgcttgg
    15061 caaaacgaag cttggattca agtttatctg cgtgagctac gcaggcaccc agcatggata
    15121 agaaggcatc aaagaagtga taatcttgaa tcagatagtc ctttaagacc ttattctcaa
    15181 ttgtccccgc aaaaagttcc ttaacaaaac gatgattgat tgcagcctgc caatccttct
    15241 gactgctttt taataattct ccaacagtca aacctggctg aaatgcatag tcttgtgttt
    15301 ccatatttac ttctcctctc tttacttgtt agtaattaat aaaacagcaa gaaatatcaa
    15361 gcaaaatcgt aattccactt gatcctttta aagcacatcg agagcattta cagagagcta
    15421 actaaacaag cctatccagt ttatataaac aaaaaactcc aattacaatc aagaattaga
    15481 gttgacttac aagattagac cgttcatttc accatacgaa aaaactgttc acatttccct
    15541 tcgccagtct taactgtatc aggttcaatg ggtattatct cagcctaaag caccccaaat
    15601 gtctctatta tttaattact gaaccagtat agcaaaaaat gaaagcccta gcaagatatt
    15661 tgaccgaaaa atatctttat atacaatata ttgaaactag aatagtacac ctctacttct
    15721 aaaacattgt tagaaatcga tttaactgtc ctgattgatt tgtcctattc ttatttcatt
    15781 ttactatagt tttcgatagc gatttattct tccaatacac gaagaaaaac ctccacattc
    15841 agtgaaggca atctgtttta tcaatacaat tttaagtcac gagggtcaac tgggaaggtt
    15901 gggttgtatg gattgtgacg gagcttaaag tgtttgacat cttcaatggt ctgagctcca
    15961 gacaattgca taactgtctt caattccgca ttcaagtgtt caaagacttg acgcacaccg
    16021 acactaccac cgagagccaa gccataaata acagggcgac caatagctac caagtctgct
    16081 cctgaagcca aggctttaaa gacgtgttga ccacgacgaa caccagagtc aaagacaatc
    16141 ggcacacgtc tatcaactgc ttctgccact tcttgaagcg agtcaaaggc agctggtcca
    16201 ccgtcgattt gacgaccacc gtggttggtt acccagatac cagaagctcc tgcagcaagt
    16261 gaacgttcaa cgtcctcacg gcattgtggt cccttgacat acacaggaag accagagtat
    16321 tcagcgataa attctacatc gcgtggagac aagcgttgtt tagctgattt gtaaacaaag
    16381 tccattgatt taccagcacc ttctggcagg tattcttcaa caatcggcat gccaactggg
    16441 aagacaaaac cattacgctt atccacttca cgattccccc ctacagtagc atctgccgtc
    16501 aagacaatcg ctttataacc ttcagccttc acacggtcca tgatgtggcg gttgataccg
    16561 tcatccttac taaagtaaaa ttggaaccaa tggggtgtcc cttgaagggc ttcagaaatc
    16621 tctggaaggt caacagtaga gtaagagctg gttgtataaa gagaaccaaa ctcatgcaca
    16681 ccacgcgcag tcgccacttc cccctgttca tttgccaatt tatgagccgc aacaggcgcc
    16741 ataatgattg gtgaagatag tttttcacct gcaaattcaa tctctgtact tggattttca
    16801 acatcgcaaa gtgtatgagg aacgatgagt ttgtggttaa aggcgcggat attctctctt
    16861 aaagtgaaag tatcttccgc cccactagcg atatagccaa atgctgcttt aggaataact
    16921 tgttgcgcca ttggctccaa atcataggta ttgatgaagt ctacatgacc ttctgcattg
    16981 cttgttttat atgacataaa atgccctcct tgattaagta agcgtttgct ttttactaca
    17041 caactataat aactcttttt tcaatcattt tcaagagttt tgcttaaaaa ccatcttatt
    17101 ttttcataca atatactagc cctactttcc ttaaactcta aaccttagtc tatattaagt
    17161 gaatcgttga gattttttgc tgccaggcat ttgaactact tttttatttg cggattctat
    17221 ctactaatac tataaaaaaa acaagtgaat aagacaccag aacatcctct aataggacct
    17281 atggacttat atcagtccca tatatactgt ttaagcaaga tactatccta gttgacgcta
    17341 acttcctatc ccacttatta attttttatt tatagtgaat ctgaacaaat caattgggga
    17401 atccaagtca atttctagta ctttttgaac agtttcagcg tactatcgta aaatgaaata
    17461 aaacatgcac aaattgatta gggaatttaa accaatttct aacaatgtct tagaaatcaa
    17521 agtgtactat ttcaacttca atatactaca cttcattttc tccttaaatt cagtctcttt
    17581 ttgaatcaaa aaatcctctg gtaagagcca gagggtaaga atttatttca ttgttgggaa
    17641 gagcaataca tcacggatag ttgttgtatc agtgaggagc atgcagagac ggtcgatacc
    17701 gattcccaaa ccacctgttg gtggcatacc gtattcaaga gcctcgatgt agtcatagtc
    17761 gatgcctgtc gcttcatcat caccaagttc tttagcttta gcttgggctt caaaacggct
    17821 aagttggtcg attgggtcgt tgagctcagt aaaggcatta ccgtactcct tagtcatgat
    17881 aaagagctcg aaacggtcag taaagcgttg gtcttcagga tttttcttag cgagtggaga
    17941 tacagctact ggatgtccat agacaaaggt tggttggatt aaagtttctt caacaaactc
    18001 ttcaaagaag gcattgatga tgtgaccaac ctcagtgtag tgtttctcaa ctggaacttt
    18061 cttctcagca gcgatagctt tagcttcttt caaagtcatg tcttgccaga aatcgacacc
    18121 agtaatttct ctgatagcat ccaccatatg aacacgctta aatggttcgt taatcttgat
    18181 ttcagtacct tggtagttga ctgggccatc gcccttaact gatttagcag catgttggat
    18241 aatgccttcc gtcaagtcca tgatatcttg gaagtctgca taagcttggt aaacttcgat
    18301 agaagtgaac tcagggttat gagtagcatc cattccttcg ttacggaaga tacggccaat
    18361 ttcatagaca cgttccatac cacccacgat aaggcgtttt aagtgaagct cagtcgcgat
    18421 acgaagcacc atgtcaatgt tttgggcatt gtggtgggtg ataaatggac gggcagcagc
    18481 accaccggct tcattatgaa gaacaggtgt ttccacttca aggaatcctt tttggtcaag
    18541 gtaacgacgg atttcagaga tgatttttga acgagtgaca aagcgttcaa agctttcacg
    18601 attagaaatc aagtcaaggt aacgtttacg gtaaattgtt tcaacgtctg tcaaaccatg
    18661 gaatttctca ggaagaggac gaagagcctt agacaagtgt gtgatgtggg ttgccttgat
    18721 agagagttct cccatatccg tacgcatcac ttcaccttcg acaccaagga agtcaccaag
    18781 gtctgctttt ttgaagattt cgtagttttc ttcaccgaca gcatccttac gaacgtagat
    18841 ctgaatctgg ccttcgcggt cttgaaggtg ggcaaaacca acttttcctt taccacgttt
    18901 ggttaccaag cgtcctgcga tagtagctgt ttcgttttta tcgtgtaatt gttctttatc
    18961 gaggttggca tatttatctt ttaattcttg tgaatttgca gtacgttcaa aacgttttcc
    19021 gaaaggatcg attccttgtt cgcggagcgc agccattttt tcacggcgaa cgatctgctg
    19081 gtcatttagt tcttccatat gttctgtaga catgggatcc tcctagtttt actcaaaatt
    19141 gaatacgatg agtcattttt tgcgatactc ccattttatc ataaataagc aagaaattca
    19201 cggataatct ttaaaaacta aaaagaacct gacgctaaaa tcactggaaa gaagtgaaag
    19261 tatcttccgc cccactagcg atatagccaa atgctgcttt aggaataact tgttgcgcca
    19321 ttggctccaa atcataggta ttgatgaaat ctacatgacc ttctgcattg cttgttttgt
    19381 atgacataaa atgtcctcct taataagtaa gcgtttactt tgtatattat aaaaatatat
    19441 taactctttt ttcaaaactt ttcaaatatt ttgtttggaa atttcagaaa ttttatgtct
    19501 atgataaaaa tccttataac ggcaataaaa aatagatatt atccaaagaa gattttaagt
    19561 gctacaataa ctgtattatt tctagatggg aggttctatt tttggattga tccattgttg
    19621 aacaatatct accactatat caaaaggcat tctttctgac cttgcatatt gcagtttggg
    19681 gaattttggg atcctttctg ctcggtttaa tcgttagtat catccgacat tatcgaatcc
    19741 ctgttttagc gcaagtagcg acagcctaca ttgaattgtc acgtaatacg ccccttttga
    19801 ttcaactctt ctttctctac ttcggtcttc ccctaatcgg gattgtccta tcttcagaag
    19861 tctgtgcaac gcttggactt gtctttttag gaggctccta tatggcagaa tctttccgaa
    19921 gtgggctgga agccatcagt caaacccagc aggagattgg cctcgctatt ggtctgacac
    19981 ctctacaggt ctttcgctat gtggttcttc cgcaagcaac agcggtggta ctcccctcct
    20041 ttagtgccaa tgtcattttc cttatcaaga aaacctctgt tttctcagca gtggctttgg
    20101 ccgacctcat gtacgtcgcc aaggatttga ttggtctcta ctatgagaca gacattgcgc
    20161 tagctatgtt ggtagttgct tatctgatca tgctgctacc catctcactg gtctttagct
    20221 ggatagaaag gaggacctgc catgcaggat tcgggaatcc aagtactctt tcaaggaaat
    20281 aatctcctga gaatcttaca ggggttgggc gttacgattg ggatatccat cctgtctgtc
    20341 ctcttatcca tgatgttcgg aacagtcatg ggaatcatca tgacctccca ttctagaatc
    20401 atacgatttt taacacgatt gtatctggaa tttatccgta tcatgcccca gctggtgcta
    20461 ctcttcatcg tttactttgg cttggctcga aactttaata tcaatatctc aggtgagact
    20521 tcagctatta tcatttttac cctctgggga acagctgaaa tgggagactt ggtacgtgga
    20581 gctatcactt ctctccctaa acatcagttt gaaagtggat aggcactcgg cttgactaat
    20641 gttcaacttt actaccacat catcatccca caagtcttaa gaagactgct accgcaggct
    20701 atcaatcttg tcactcggat gattaaaacc acttcattag ttgttttgat tggggttgtg
    20761 gaagtgacca aagttggaca acaaatcatc gatagcaatc gcctgaccat cccaactgct
    20821 tcattttgga tttatggaac cattctagtc ttatatttcg cagtttgcta ccctatttcc
    20881 aaactatcca ctcacttaga aaaacattgg agaaactaaa tgtctgaaac tatcttagaa
    20941 atcaaggaac taaaaaaatc cttcggagac aatcccatcc tccaaggact ttctctagaa
    21001 atcaaaaaag gggaagttgt tgtcatccta gggccatttg gttgtgggaa aagtaccctc
    21061 cttcgttgcc tcaacggctt agaaagtatt caaggtggag atattcttct ggatggtcag
    21121 tctatcgttg aaaataaaaa agattttcac ctagttcgcc aaaagattgg catggtcttt
    21181 caaagttatg aactctttcc ccatctggat gtcttacaaa acctcatcct aggccctatc
    21241 aaagctcaag gaagggacaa gaaagaagta acggaagaag ctttgcaatt actagatcgt
    21301 gtcggtttac tggataaaca acatagcttt gctttgcccg tcaattatct ggtggacaga
    21361 agcaacgtgt tgcaattgtc cgtgccctcc taatgcatcc agaaatcatc ctttttgacg
    21421 aggtgactgc ttcgctggat ccagaaatgg tgcgtgaggt gctggaactt atcaatgatt
    21481 tggcccaaga aggccgtacc atgattttag taacccacga aatgcagttt gcccaagcca
    21541 ttgctgaccg gattatcttc ctcgaccaag ggaaaatcgc tgaagaagga acagctcaag
    21601 ccttctttac caatccgcaa accaaacgag cccaggaatt tttaaacgtc tttgacttta
    21661 gccaattcgg ctcatatcta taaaggagat tcttatgaaa ctattcaaac cactcttaac
    21721 tgttttagca cttgcctttg cccttatctt tatcactgct tgtagctcag gtggaaacgc
    21781 tggttcatcc tctggaaaaa caactgccaa agctcgcact atcgatgaaa tcaaaaaaag
    21841 cggtgaactg cgaatcgccg tgtttggaga taaaaaaccg tttggctacg ttgacaatga
    21901 tggttcttac caaggctacg atattgaact agggaaccaa ctagctcaag accttggtgt
    21961 caaggttaaa tacatttcag tcgatgctgc caaccgtgcg gaatacttga tttcaaacaa
    22021 ggtagatatt actcttgcta actttacagt aactgacgaa cgtaagaaac aagttgattt
    22081 tgcccttcca tatatgaaag tttctctggg tgtcgtatca cctaagactg gtctcattac
    22141 agacgtcaaa caacttgaag gtaaaacctt aattgtcaca aaaggaacga ctgctgagac
    22201 ttattttgaa aagaatcatc cagaaatcaa actccaaaaa tacgaccaat acagtgactc
    22261 ttaccaagct cttcttgacg gacgtggaga tgccttttca actgacaata cggaagttct
    22321 agcttgggcg cttgaaaata aaggatttga agtaggaatt acttccctcg gtgatcccga
    22381 taccattgcg gcagcagttc aaaaaggcaa ccaagaattg ctagacttca tcaataaaga
    22441 tattgaaaaa ttaggcaagg aaaacttctt ccacaaggcc tatgaaaaaa cacttcacct
    22501 aacctacggt gacgctgcta aagcagatga cctggttgtt gaaggtggaa aagttgatta
    22561 gtcattaact cttaaaagga actggatttt aagatccaat ccctttttaa gattttacct
    22621 ataacatcct gagtctatct aagatgttca atctgaacac agtgtacata ctttatcttc
    22681 tattgcatat actttatcac ataagatacg aatatcctct tcactatgac tagcaatcaa
    22741 aattgttgtc cctttttcac tagagagctt tctaaacaat gttctcatat tttctacact
    22801 tgatttatcc aaggcattca taggttcatc tagtaaaaga atagagggat tctccataat
    22861 tgcttgagca atccctagct ttttcctcat acctagcgaa taagttttaa ctttctggtc
    22921 tttttgctca tatagaccaa ctattttcag tgtatcattg atttcctgat taccaactac
    22981 tcctcgtatg cttgccaaat attgtaaatt cttaaagcca ctataataat ttataaaacc
    23041 aggttcttca atcaaagctc ccaaattagc tggaattttt ctctcaggaa caatattttc
    23101 cccattgatt aacacttctc cataagacgg actatataaa ccagctatta atttaaacaa
    23161 tacacttttc cctgagccat tcgcaccagt aattcctata atttccccct gtttacaact
    23221 aaagttaagg ttttgaaaaa cacatgtttt ttttaattcc aactgaatat tttttaatgt
    23281 aattatttca ttcattctat aaacctcctc ttttgacgag tgaaatagaa aatgctttta
    23341 aaaagaaaga ctaaaaatag caactgaaga aataaatctc gtcctatatc tccattccct
    23401 cgatttaaaa tataaaatag ataattagtt cgatttccta caaatagacc accaaacaca
    23461 atcatgagta aaaagaagct aacacaagaa aagttcattt gctcattcgc tcctagtacg
    23521 tataacataa agcaaaacaa gactaacaca caagcattca aagaatcaac tataaacaaa
    23581 actcctatat cccagtttgg taactgtaac ataaattgaa tcactagaac ttttaccatg
    23641 attaaaatga gtccataaag aaaacaggtc caaatctgat acctaatcca gagcttaata
    23701 gaagaaaatc gaatcacttc cataaagaaa tcggatgctc ttctacgata tacaactgct
    23761 agaaaaaatg tatgaataat aaaccaatga agcaaccata tagataagac taaaaaagag
    23821 ttttgactca gattaggccc ttttaaaatt tctataacaa gtctatcatt tccttctaac
    23881 caataccata atcctaaaca aatcaatatc caaaaaagaa cataacccca aaagtacttg
    23941 gtatagatta tctgattcaa cctccacatg tgactactta actttcccat ttccaacttt
    24001 tacactctcc tccagtttct atgaacagaa aatacagtca atggaattat gatagatagt
    24061 aatgtaagcc aataaatcaa tgcatacgga ttggaattta ccatatactg aaaaattggc
    24121 aataatccaa ttatcccatt gtccaactga taaatccaga ataaggattc tacaaataaa
    24181 aaagtaaaca gaaatactaa gctcatgttt gattttttaa accaagaaaa actgctaata
    24241 gtaagtaagg ataaaaagaa atagtatgct atataagaga aaaaaaatcc tataaaaaaa
    24301 ctagcattgt ttgcaatact tataccataa aattctctta aaaaatcaac ctcctttatc
    24361 tccaaagaga agctaaaacc attactaaat gcaatcagaa aaatcaataa aaataaagtc
    24421 gccgtccaaa tccccgtact aagagctgct aatttgaaac taaaactggt aaagtgctta
    24481 attgatttca gacgaatacg acactccaac ctattaaaat agttattcat caaataaaaa
    24541 aagaataata tatatgtgaa cggaaagcaa tatactccag tcgtcatatc ttgaagtaaa
    24601 actaagatcc attctaatac atttggatgg attgaatatt ggcgacagcg caataaatat
    24661 actgtactag ataaaacaca ggatagcagt aatataaaat aaaccaatac tgctaagaaa
    24721 tcttttttat aaaattgaac aaattgtttc attatacata gtcctctgaa tgtagaaaaa
    24781 atgtaccata aacaaccaaa caactaacaa ataaaataaa agcaagatgc ccactaacta
    24841 aggaaagact gatatctttc tgatatccca aagctagcgt tgtcacaggt tctaagtaag
    24901 atagccctaa aatagcccat aaaataccac caaccatcat ataggcaact gggatgaaaa
    24961 tagctcctaa ttttttcttc actagcaaag cactagctag tccaaaaata gagaacacag
    25021 cgccccaaac tccataccag agagtcgtca caagactata gagaaactga ttggaatcaa
    25081 ataattcttt taaggcacca ctataatctc caatataaat ttcctgataa ggagtcacta
    25141 aaagattaat tcctaataat aataaatagg ggagaaaaaa gactagaaaa gaagaaataa
    25201 ttgcagtact acctacaata gctagatacc tctttttaga aattcggcac aattgtgctg
    25261 ttagaaaatg actctcagca tcctctatta tctgactaga atagggcagt gtacagataa
    25321 gtgcagctac taggctaatc ggtgaaaatc ctcgaataga agaagcggca aaaaaaatcg
    25381 ataaaccttc aattttataa ataccattga aagcaaggaa atttcctaaa ctcatgcaaa
    25441 gaagggtcaa aaataaagac atataaaacc gaggtgattg aacgactcgt acaagattac
    25501 aaatgaaaaa ttccatcctt actcctcctt ataataaaaa tagggtgtag cattcttttt
    25561 tcatgctaca cccacaatca accatcttta aggcttactc tgacaagtaa gttaataaga
    25621 atctggactc caagaacctg aagtatgaat tcttacataa tttccaaatt gtggcgccat
    25681 agctaatcta gtaccagaac caatataatt gtcaccacct ccattatagt acatgacaat
    25741 cctagagcca gaccccaatg aatataccgg ggtaatatct gacccactat aggcgctacg
    25801 aatagaggta tttaaccttt taccgccacc agtgctgtca ctattattaa ttccagcaga
    25861 ggcgttttct ttctcaagct cactagttgt atccgaaccc caacgcggca acgttaaatc
    25921 ataatttcca atctgtctag ctaaaactgt agggagaaac aaactagatg caattgtaac
    25981 tacgcaaaaa aggaatatat ttttcttctt ttcatgacat cgtcctctta agaagtgata
    26041 aacaagatag ttgattgatc aatttgatac atattacatt ttcattatat caataaaaga
    26101 aagcgttgtc aattatttta tttaaaatat tgtcatattt taaataaaat ggtaaaagag
    26161 actcggtagc ctcgtctctc tttatcttac tgacctaacc ttcttgccaa ttttcttggt
    26221 cttctttaaa gcgttttaga agatcaaggc cctctggcgt gatgtaacct tcttcttggg
    26281 ctagatggat aagctcgcta tagtttgaaa gcgtcacaag tttaacacca gcatctgcaa
    26341 agttcttatc tgcttttggc aattggtagc tgaaaatcgc tacaactcca agtacatctg
    26401 ctccttctcg cttggctgct gctacagctt caagaactga accacccgtt gaaataaggt
    26461 cttcaaccac taccattttt tgaccttgag ctacgcgacc ttcgatttga ttaccagctc
    26521 cgtggtcttt tggtttgcta cggatgtagg caaaaggcaa gtccatctta tcagcaataa
    26581 tggctccgtg tggaatccct gctgttgcag ttcctgcaat cacttctact tcaggaaagg
    26641 cttctttgat agcttccaca aaaccatttt caattagggt acgagtttct ggataggcta
    26701 gtgtcacacg attatcagtg taaatcggtg acttgatacc agatgcccaa gtgaagggtt
    26761 cctctggttt gaggtaaacg gcttggattt tcaagaggtg gctagcgata tctttagcaa
    26821 gtgtcatggt attctccttt tatttttcta atctagttct ttaattccag tcctgtgtcc
    26881 attcatcctt gatggcatga taagctgcaa caggatcctc agcttgggta atgggacgtc
    26941 ccactacgat atagtcactg ccgatttgat aggcatcagc aggtgtcatg actcgttttt
    27001 gatctccaac tgcaacacca gctggacgaa tccctggtgt cagacagata aaatctggat
    27061 tggtagcctg cttgatgact tgtacttcct gagccgagca aacaacacca tccaagccag
    27121 cttcagctgt cttcttggca tagtgaatca cagactcttg cagactggtt tggatatttt
    27181 gaaactcctg catctgagct tctgacgttg atgtgagctg cgttacagcg atcaatttgg
    27241 cttgactccc aagaccttca cgcgccgcct tcatcatctc tacaccacca gccgcatgga
    27301 cattagtcat atcgacacca agctgagaca agaccttcat ggctgacttg actgtattag
    27361 gaatgtcatg aagtttgaga tccaaaaaga cactatgacc caaacctttt aagtaggaca
    27421 caatctcagg ccccgctgcg taataaagct ccatccctac cttgagataa aggctttctt
    27481 ctgctgggaa aagagctaaa aattccttga ccgcctcaaa actaggaaaa tcaagagcaa
    27541 tgattggacg atgttctcgc ataggtttct ccttttacct ttactagtga gagagtctgg
    27601 ccaacagaag ccacgaaaaa aggaacctgc caacagcaag gttccacgaa aaatgggtag
    27661 tctccaccct ttcaccgtct aaccttagct gcctctctgg actgctttaa aggttttcta
    27721 ttattctatt atttctacta gcacttgtca agtaaaaaca tggtcactaa agaactataa
    27781 gagaaaaggt aaacctagcg acgcgatgag cgctgggtcg tttgatttcg attgctctct
    27841 tcctcttgtt ttttctgttc ttcttcctgt tttttctcgg cttccttggc ctcttgtttg
    27901 gctttttcct cagcctccat aattaattta tccgccacag tgtaactgta aattccagct
    27961 tccatgtcga ccacactcgg ttctgacaat tgtggcttaa tcttactgta atatggcagt
    28021 ttcttactca tttcagatag aggaaccaag acttcgtccg aatcattcat ggtcaatcga
    28081 attaaatcgg atgtcacctt gcttggggct aattccacct tttggatagc cgccttgagt
    28141 tctgggctaa tttgagcaag ttctgagaca aaaaccttga tttgttcact atcattaaag
    28201 agaactgata aataagtttc tggtaaactg ttcagactca cagaactagt ctcaagctga
    28261 ccactggaaa gaataggata atgattttca ccagaaatat agtaggccac aatatcatat
    28321 tccttgacct taatagtgaa cttagttgga aattgataga caagttgagc tgattcaacc
    28381 caatagttag acttaatctg cttttcatat tttgccttgt ctagcagaag gttaatcgta
    28441 taatccgaat cctgaatgcc tgaagcctgt cgaatatcat cagctgtagt ttgcaccgtt
    28501 ccctcaacac gaatatcttt catggtcgca taaggactga gcaagtaggc agagacaatc
    28561 aataaaagca gacttggaaa taaaatcgtg aaggctcgca agatatggat accaggaatc
    28621 tttgctttgg ctggtttttc ctttgtagcc tttttagaaa gctttttatc ctgttcctcc
    28681 ttctctttag actctggttc ttctttctct tctttctctt tgtcagcctc tgaggatgct
    28741 actttttctt cagactcttc cttagctgat tctgaatctt cctggtctgt ttcactctcc
    28801 tggtcctgtt tgtcctctga cttctcagat tcttctccca ttcgagcttg tctttccttt
    28861 tccttctcct cagctagagc cgcctcttct tcagccttct tttttagata ttcttggttt
    28921 cgtttctgcc attctgataa ctctttcaat tcttcgagga tttctttgtc ctcatttttc
    28981 ttatcttttg acatttactt tccttatgat aaatcttttt tcaacaattg ataaaaatct
    29041 gctagagatt tcaattcctt agaagccttc atcttagctt ggtaatcttc cttgtgactt
    29101 agtaagtgag aaagcttctc ttccaaacta tccaaggtca aatcgctttc ttgaaggtct
    29161 tctgcatagc ctttttttac aaagtaagct gcattttcaa gctggtcacc acgactagct
    29221 tcacgaccaa gcggcacaat gacatgcaat tttgctatcg ccaagagctc aaaaatcgta
    29281 ttggcaccac ctcgtgtcac aacaatatca gccaattcca tcaagggttg atagagatcg
    29341 gtcacatagt caacacgaaa aagattttgg ctcaactcat tcaggctaga atctccagtt
    29401 agattgataa tattgtagcg ctctgttagt tctttcttat ggtctgtcac caattggtta
    29461 aagacacgag cacctgcaga accgccaaca aacaatacag tcggcaattt atgattaaag
    29521 tggctttgaa tatccaccaa ttcatctggt tctggatttt tttgatctga aaccttggtc
    29581 actgctccca catgctcaac cttagacaaa ctcgaagctt gctcaaaggt tgaatacatc
    29641 ttagtcgcaa atttataggc gattttattg gccaagccca tagacaggtc agattcgtga
    29701 ataaagacag gcactcctga cacacgcgca gcgataacag gcggtactga gacaaagccc
    29761 ccctttgaaa aaagggtctg tggacgaagt cgcaacatga taaagagcga ttggacgatt
    29821 ccccagcaaa ctttgaagac gtccagcata ttttgccaag agaaatagcg acgcaatttt
    29881 ccagtcgcaa tagaatggaa ggtgacatcc aaacctgact taaggatttc ttggtgttcg
    29941 ataccacgct tgtccccgat atagtggact tcccaaccat cttcgatgaa cttgggcatt
    30001 aacaaaagat tgagggtaac gtgtccaacc gtccccccac ctgtaaagac aatttttttc
    30061 atattattct tttaactccg ctactgtgtc gataaagagg tcgccacgta cttcaaagtt
    30121 agcatacata tcccagctgg cattggcagg actaagaaga accacatctc cttgagtcgc
    30181 aagctcatag gccttgcggg tcgcatctgc aatatctgtc gcctccacat aagcgacacc
    30241 agccttgtct gctgcccgtt tgacacgttc tgcagattga cccaggatga ccatcttctt
    30301 gagtccagta atgtctggca ccaattcgtc aaactcattg ccacggtcca aaccacctgc
    30361 aatcaagacg accttgctgt tatcaaatcc tgacaaggct ttttgagtag ccaagatatt
    30421 agttgattta ctgtcgttat agaatttaac acccttgatg tcatccacaa actggagacg
    30481 gtgtttgaca ccaccgaagg ctgaaagagt ttccttgatg gtttgattgt ccacaccacg
    30541 aagcttggct acagcaatag tcgcaagggc attttccaca ttgtggctac ctggaacacc
    30601 gatttcattc gctgccatga ctacttcacc acggaagtag agttgaccat cttccagata
    30661 agctccatca accttttcaa gtgttgaaaa tggtacaaca gtggcttctg tcttggaagt
    30721 caagtctttt gccaagtctt gattaaagtt caagacaagg aaatcagctg ctgtcatctt
    30781 gttctggata ttccacttgg ctgctacata ttccgaaaat gacccatggt agtcgatatg
    30841 agttggcatg aggttggtaa taaccgcaat ctctggatgg aattcttgaa cacccatgag
    30901 ttggaaagaa gaaagttcca taacaagcgt gtccttatct gatgctattt gagcaacctg
    30961 actagctgga tagccgatat tccctgataa aagaccatgt tgcccagcag cagtcaaaac
    31021 ttccccaatc atagtcgttg tggttgtctt accgttcgat cctgtgatac caataatcgg
    31081 tgcttctgaa atcaaataag ccaattccac ctcagtcaag actggaattc ccttggccaa
    31141 agccttttca atcatgggat tgttgtaggg gatacctgga tttttcacca taagggcaaa
    31201 ctcttcatcc aagagttcca aaggatggcc acctgtaatg accttgatcc cttcttccag
    31261 caaactttgg gcagctggat tgtcctcgaa aggtttccca tcatttactg tcacaatggc
    31321 acctagcttg tccaacaaac gagctgcaga ttcaccagac ttggccaaac ctaaaacaag
    31381 gactttctta tttttaaatt gatctattac tttcatgtct cgaactccat ttctactcct
    31441 actattttac catttttatg gaaataaaaa agccacaaag tgtgtttgtg actctttctt
    31501 ctaactgaat cttaccatat catctatgtg ataaatcggt aactcgaatg acctgatcca
    31561 cttgttccca aatcagagga ttgtgggtcg caataataat ggtccgattc ggatttttta
    31621 aagattctag gatggaaagt aattcctcag agtttttggg gtctaaggaa gtggttggtt
    31681 catctgcgag gatcaaaggt ggatccttta aaattatctt cgctaatgca acacgttgtg
    31741 cttctcctcc tgataactca aatataggtt gcttcaaatc caaataagag aggtttacac
    31801 agtttagagc ttgtttcatc aaagagattt tctctttttc cttcaacttt ttaccaacta
    31861 aacccagatt gagattctct ttgacggttt ggctttcaat taagccaaaa tcttgaaata
    31921 agtatcccaa gtaatctcta aagaaaacag aaggcttgat gtccttaaga gaagtaccat
    31981 catagatgat ttgtcctttg tcatatggct ctaatcgtcc aatcatattc aagaatgttg
    32041 tcttaccaca gccccttgta ccgattaagg cataaatttt cccaccttca aaatgaagat
    32101 ttgtatctga aaatagctga cggcttccaa attttttaga tatattcttt agttcaatca
    32161 tcctattttc ctttcataat tgtcatagaa acacgagatt ctttctgcgc ttgacggtaa
    32221 agcgtcagaa ctgcactagc tagaaagact aataaagtga gcaagccaat caccaagtct
    32281 cgactgctta aaataaagag actagcacca aatacaaaac tggcaaattg actaaccata
    32341 tactgagcat gtgtttcaaa aaatcgtaaa cctgaaattc gtttaatcaa aatatctcgg
    32401 cggaattgct cgaaatatag aagattgaca gaataaaata gtaacaagga actagctatc
    32461 cccacaatag ctcctaagat taaagttgct gtttcagttt gaacttcatt ataacgagtt
    32521 agataaacac ttcttccttc tttaagatag gatacttgct cataaattcc agctttcttc
    32581 aagagttcta gcccactctc atatcctttg ataaagagtt gttttccagc attgatagac
    32641 caactagata aggatataaa actatcacct gtagaagtcg gcgtgaatac cactaaaatc
    32701 ggatcagtca aatactgagt agatacggga ttctcaccgt tattataaac aaaccgcttt
    32761 tctcccattg aaagataact aacgtgcgct ttcatctcat aatccaaagg agcacttgcc
    32821 tcctcaccag attttccata ataactcaat ctttcttcaa aaactttctt aagttctgct
    32881 tctcgagagc gcaaatgttc tgggagcaag aggataaact cacctttttg gagatgggct
    32941 aacttctgtt tggtctcagc atctaccacg accttttcct tgtccaaata actgggacta
    33001 acatagagcg tattagcatc tggactatag gtatccagtg tctctccctg ttcatttttt
    33061 ccttgtggat tggcaaaatg gagcagatta tcctttacat aaagagcttg ttcttcttcg
    33121 attgcttcct tggcaaaggc ataccacttg ctctgatttt ctgtatcttt tcctctatca
    33181 cctaagccaa aagaaatttg ataatagtct gctctatcct gccatgcttg ttttgaaatt
    33241 tcaagttctt tcaatcgttg gtaagacatc aaacctgtct taacagcgta gcctactgta
    33301 aagacagcaa ccaactgaca caatagggtt aaaatcatca ggcgtttaag gggtaatctc
    33361 cccttaataa cgggaactaa tgctttgtaa ctcaaactca ttagataaag aagcattagt
    33421 aaaattgaaa tcgccaataa aaacaacaga tagaaactaa tcccaaaacc ataggtggct
    33481 aacaagatag gataaaacaa accttgacta aaaagaacga ctcccccacc taggaaggaa
    33541 aggagggctg atagaaggag ccatttgata tcagtagata aagaatgccc catgatggat
    33601 aagagagtct gaccagaaaa gagttttata cctgctgctc tcatttcctt aatccgagtg
    33661 ataatcacta aagcaaagaa agataagcca aatattgcta aactaattaa aataagggga
    33721 tttagtaata ttcgaaaagc aagaaaatag ggcggtatct ttcggtcagc acttgcttta
    33781 taacccaaat ctcctaattt atcggcaagc ttttctttcg tcaaggagcc tgacaaaagg
    33841 agataactat ttagcggatc actacgttca cgactttctt ggctagcttc ttggaattct
    33901 tttggtaaag ttccctgacc ataagttgca taagtaaagt gagtcgtccc atccttactc
    33961 ggctctacaa ttcttctagc tattaaactc tgttctgagt ttgcaaaatt ctccaattcc
    34021 tgttcaaata cctcacgcgt cggttcctga gtatcttttt tgacacgaag taaagaaacg
    34081 gaatcatagc ttgcatataa atattgtggc gcacgtaaga caataatcca agcaaggaag
    34141 aagctgagaa aaaagttgat aataatatga atagtttctt catagtagac tccttgtaaa
    34201 caaaattccc cctgtaattt cttacaaggg gaacgattta aatcaatgaa cgattagtca
    34261 taatcacagt aaaatgctac ttgttctccc catttagtcc aaatccatgc ataggaggtt
    34321 tttccagcag aagcttctcc tttatctgaa tgactattcc atctacttac aagagaagaa
    34381 taatgatatt ttttaccatg atagtaattt gaaaaagccc aaccacctcc tgaaccttct
    34441 ccatacgtcc atactcctcc atctggatat tgtacagcag ctgatgcagc tcccaataat
    34501 gtaaaacttg aaataagagc tagagcaagt aatctatgtt ttttcgtttt cattttattt
    34561 tttctttcaa aaaaagcaca ccttgagcaa caatgcaaca aaataaaccc tcctctctct
    34621 tttgttgaaa ccgctttctt atgtgataaa aatatcattt ttattatttg ttgtcaagga
    34681 aaaaatcgaa ttttttagat attttactac attgcctcta tgaataatat tatatagtag
    34741 ttttatttta aaataatatg caaccagtac taaccaaata taaaatagat gccattaacg
    34801 aattttattc aagtttttcc cattcatact atccaagcaa aagagatgat gttatagtac
    34861 aaaacaattc aaactattgt aaaattccta gcaaaaaaga gagccaaaac tctctttttt
    34921 atcttctttt actttttttg actggcatga gtgtaatgtc tctaacacta aagtaagcta
    34981 ggatcaacat ggctattgct aggaatattt ctgttggtaa ttgaaaaatt ttcagaaaag
    35041 atagaaccaa taaaatcaag agtgccacta aaatacatac catagcgacg atattgactg
    35101 tccctttaat gctttctggt gtcgcaaata catagagtag gagcagtaaa attcctagga
    35161 ctaaatagac catctttctc tctttctagc tcttattcag ctgatttttt cttcttgtta
    35221 gctttctcac gctctgcttt gttaaggatt tgtttacgca aacggataga ctcaggcgtt
    35281 acttccatgt actcatcgtc gttcaagaac tcaagagact cttcaagtgt caagatacga
    35341 ggcgtcttga taacagctgt ttggtcctta gtagctgaac gaacgttggt catttgtttt
    35401 gccttcgtga tgttaactgt caagtcattt tcacgagagt tttcaccgat gatcattcct
    35461 tcataaacct cagtacctgg gttgacaaag atcgtaccac gttcttcgat agacatgatt
    35521 gagtaagttg tagccttacc agcatcgata gaaacaaggg caccacggtg acgtccacca
    35581 atttcccctg gaatcaatgg caagtattgg tcgaaggtat ggttcatgat accgtaacca
    35641 cgagtcattg acaagaactc agttgagtat ccaatcaaac cacgcgctgg aacaaggaag
    35701 accaaacgag tttgaccatt accagttgaa atcatatcca acatttcacc tttacgttca
    35761 gaaaggcttt ggataacaga cccttggtat tcttctggag tgtcgatttg tacacgttca
    35821 aatggttcac atttaacacc gtcgatttct tttacgataa cttctggacg agatacttga
    35881 agttcatagc cctcacgacg cattgtttcg ataaggattg acaagtgcaa ttctccacgt
    35941 cctgaaacag tccatttatc tggtgaatca gttgggtcaa cacgaaggga aacgtctgtt
    36001 tgcaattctg cctgcaagcg ttcttccacc ttacgagaag ttacccattt accttcttta
    36061 ccagcaaatg gtgagttgtt gaccaagaaa gtcatttgaa gagttggctc atcgatgtgt
    36121 aggattggaa gagcttctac tgcatctgtc ggagtgatgg tttcaccgac aaagatgtct
    36181 tccatacctg aaacggcaat caagtcaccc gctttggctt cttggatttc acgacgttcc
    36241 aaaccaaaga aaccgaagag ttttgtaaca cggaagtttt tagttgtacc gtcaagttta
    36301 gaaagggtaa cttggtcccc aaccttaact gtaccacgga agacacgacc gataccgata
    36361 cgtccaacga agtcattgta gtccaaaagt gacacttgga actgcaaagg ctcatctgag
    36421 ttatctactg gagctgggat atggtcgata atcgtgtcaa agattggtgc catagtcgct
    36481 tcttggtcag ctggatcatc tgacaatgaa gaagttccgt tgatcgctga agcataaacc
    36541 actgggaaat caagctggtc gtcatctgca ccaagctcga tgaaaagttc caagacttca
    36601 tccactactt ctgctggacg agctgatggc ttatcgattt tgttaacaac cacgattggg
    36661 acaaggtctt gttccaaggc ttttttcaat acgaaacgag tttgtggcat ggttccttca
    36721 taggcatcta cgaccaagac aacaccgtca accattttca tgatacgctc aacttctcca
    36781 ccaaagtccg cgtgtcctgg tgtgtccata atgttgatac gagttccgtt gtaagcaacg
    36841 gcagtgtttt tagcaaggat ggtaatccca cgctcttttt cgatatcgtt tgagtccata
    36901 gcacgctctg ccaattcagt acgtgcatca agcgtttctg attgtttcaa taattcgtca
    36961 accagggttg ttttaccgtg gtcaacgtgg gcgataatcg caatgttacg gatatcttct
    37021 cttaattttg tcatgatttc ctctataata ttcaaaattt attttctaac tgaacgatta
    37081 taccataatt tcaaataaat aacataactc aagcaagtgt aaatgttttc actccgcttt
    37141 tcttttcacg tcaagccttt tcaaagcaag cgacttatga taagataggc acagtatgcg
    37201 tttagataat ttattagccc aagaaaaagt tagccgaaag gccatgaagc aagcactcct
    37261 cagaggggaa attctagtcg atggttgccc agcccgctcc ctagctcaaa atatcgatac
    37321 aggactacaa gaactccttt ttcaggatcg aatcattcaa ggctatgaac acacctatct
    37381 tatgcttcat aaacctgctg gtgtcgttac agccaacaaa gacaaggaac ttccgaccgt
    37441 catggacttg cttccatctg acatccagtc tgacaagctc tatgccgtcg gccgactgga
    37501 ccgagataca acaggactcc ttctcttgac cgataacggt cccttgggct tccaactcct
    37561 ccatccccaa tatcatgtcg ataagactta tcaagttgag gttaatggac ttctaacacc
    37621 tgaccatatc caaacctttc aaaaaggaat tgtcttttta gatggcacta tctgtaaacc
    37681 tgcaagacta gagattctat cagcaagtcc ttccctcagt caagcctcta tcaccatttc
    37741 agaaggaaaa tttcatcaaa tcaagaaaat gttcctctcg gttggtgtta aggtgactaa
    37801 cctcaagaga atccaatttg gggacttcac attgaaccca gatttagcag aaggtaacta
    37861 ccaccctttg aaccaaaaag agttacaaat cattaaaaac tatttagaga tgagtcgata
    37921 aaacaaaaaa agctttaaaa ctaaagcttt tttcttttat ttaccgaaaa attaaggcga
    37981 ttgctacaat ccagttaact acagaaatca caattcctaa gatattaaga atcttttcta
    38041 ttttatagtc taattgtgac tctttttggt atgaaatagc caagaccaat cctatgatac
    38101 ccaaaatcag gcctacaatt ggaaataaca aaccaagaat aatcgacaag atacccacaa
    38161 aaagtggatt tttcttcttt tctttcatgt tctaagaact ctttaaattt tatacaaatt
    38221 aattatacta taaaacaata gcttcattct atcattcgac taatttggaa ataaggttag
    38281 ctagtcttca ctttcccttt ccaagaatcc aagccataag aaaggatata aatctcagaa
    38341 aaaccttgtt ttttcaagta aagagctgca tttgtaactc gttgcgcacg ttggttttcg
    38401 tagagaagga caggtttatc tttacgaagg gctgcaagac tagttttcaa ctgacttgaa
    38461 ggaatattgc gtgcaccaag gatatgtttt ctgtggaatt ctgctgggtc gcgcaaatca
    38521 atcaattgac ccgtacgaat caaggcttca aactcctcat tgtccacaat tttagccgca
    38581 cggcgaatac gaagatagtt aaagcccatc cacgccaaca ttgctagtat aagtgcccac
    38641 aaaatccaag taaccattag ttcttttctc catttttctc aatataatcc aattctacct
    38701 tgtgctctct gcgaagaact gcttctgcct ctagatagtc taatttatcc atcaaccctg
    38761 catcgtaaat ccgagatagt tccaacttca tcagttcaat atcatataag cgttttccca
    38821 tgtaaacaat aataccaaat cgtttgagga attgctgcac atcatagaat gttttcataa
    38881 gactcattct agcaaaattt tgtgtttttt tcaagaagag actcacacaa tgctccttat
    38941 tttcctatct tctttagcga ttctaaggca agtatggtac aataaaaaca tgagaattca
    39001 acaattacat tatattatca aaatcgtcga aactggctcc atgaatgagg cagccaagca
    39061 actctttatc actcagccaa gtctctccaa tgcagtgcga gatttggaaa atgaaatggg
    39121 cattgagatc tttatccgca atcccaaggg aatcaccttg acccgtgatg ggatggagtt
    39181 tctctcttat gcccgtcagg ttgtcgagca gacccagctt ctggaggaac gctataaaaa
    39241 tcctgtcgcc caccgcgaac tctttagcgt ttcgtctcaa cactatgcct ttgtggtcaa
    39301 tgcctttgtc tctttgctca agaaaagcga tatggagaaa tacgaactct tccttcgtga
    39361 aactcggact tgggagatta tcgacgacgt caagaacttc cgcagtgagg tcggggtcct
    39421 cttcttaaac agttacaacc gtgatgtttt aaccaagatg ctggatgaca atcacctgct
    39481 agcccaccat ctcttcacag cgcaaccgca tatctttgtc agcaagacca accctctggc
    39541 aaagaaagac aaggtgaaac tgtctgattt ggagaatttc ccttacctca gctatgacca
    39601 agggacgcac aactccttct acttttcaga agagattctt tctcaggaac accacaagaa
    39661 atccattgtg gtcagtgacc gtgccaccct ctttaatctc ttgattggtt tggatggtta
    39721 taccattgcg acagggattt tgaacagcaa cctaaacgga gacaatatcg tttctatccc
    39781 actggatatt gatgacccga ttgagctggt ctatatccag catgagaaaa ccagcctatc
    39841 taagatgggc gaacgcttta tcgactatct actagaagaa gttcagtttg atagttgaga
    39901 aatgataaga accaatatgt aggctagcaa caacctgcac attggttctt tttacttata
    39961 attaaaagtt tcccctgcca acttatcagc tagcttggga aagagagtat aaaacttatg
    40021 ggctaggttc aacaaaatcg ggagattgag ttctcgttta tttttgccta taatcttgac
    40081 aatcttttta gccactgcat ctgcctctaa gaggaagcgg tcaaccgatt taagataagt
    40141 tccatctggg tcagcttggt caaaaaatcc tgttcggatt ggacctggat tgactgttgt
    40201 cacatagact ccatagggca taagttcgag tcgcagagca tttgaaaaac caatagccgc
    40261 aaacttggtc gctgagtaaa gactagactt gccagtagct attagacctg ccatgctgac
    40321 gatgttgatg atatgccctt tgctgctttc cttcatacga gccgcaaggt gacgagacag
    40381 attcatcagg gcaaaggtat tgacctcaaa catctggtga atatctttat cagcaatctg
    40441 gtcaaatccc tcaaaaatcc cgtaaccagc gttgttaatc aagacatcaa tcttgccata
    40501 gcggagataa agatcagtta ccagagcttc tagggctgaa tcgtcggtaa tatcaatttc
    40561 aatcaattct gcatgggaat aatttccgta gagttgggct aatttttcct tatttctacc
    40621 aagcaagatg agttggtcat tgggcaggag tttgaccatt tcttgagcta gaccaccgct
    40681 agctccggta atgagaatag taggcatact tatcctttct gtgactgcta gatttccact
    40741 tcttccaagt ctttgaccac atggacattt tcaaaaattg tggcagcgtc cttcttgagt
    40801 ttgcttatat cttttgagag gaaacgggca ctgatatggt tgagtaggag gcgtttggca
    40861 cctgcttcta ccgctacttg tgcagcttgc atattagttg agtgaccatg gttacgagca
    40921 attttttcat cacccttgcc ataagtggac tcatgaacta ggacatctgc attgacagcc
    40981 agacgcacac tggcatccgt ttttcgagtg tctcctaaaa tagtgataat cttacctgga
    41041 cgtggcgctg agatatagtc tgctgccttg atttcagttc cgtcttccaa aacaagatcc
    41101 tggccgtttt tgattttacc aaaaagcggg ccgaacggaa caccagcagc cttgagtttt
    41161 tcagcatcca gcgtcccttc tagatccttt tgcatgacac gatagccaac acagaaaata
    41221 gtgtggtcca gctcctctgc atacacagtg aatttatcgg tttcaagaat tttacccaga
    41281 gaatcttggt caaactcatg gaaatgaatg cggtagggca gacgagaacc tgacacacga
    41341 aggctggtta agacaaatga cttgattcct tgaggtccgt agatttccaa atctgtctgc
    41401 tcttcattgg cctgaaaggc acggctagaa aggaaacctg gcaaaccaaa aatgtggtct
    41461 ccatgcagat gggtaataaa gattttgctg accttacgtg gtcgaattgt ggtttccaga
    41521 atgcgatttt gcgtaccttc tccacagtca aagagccaaa cttcgttaat ctcgtccaaa
    41581 agtttcaggg cgagacttga aacgttgcgg gctttagagg gctgaccagc ccccgttcct
    41641 aaaaattgaa tatccattcg atactttcta attaatcaat atataacatg gctgtgcggt
    41701 tttccgatcg gaaatagcgt ttgccagaaa aagcagcagc ttcttgcaat aaatcctctt
    41761 ggctgtagcc tttgagacgt tttcgaccat cagccaatct ttccaaatca gtcaaagctg
    41821 tgagactttc taggctgaca acttcctcgt ccttgacagg tttcatgtaa atcttaccag
    41881 actcttcaaa gactaattga tgggagaaaa tttgcgcaat ttcaaagagc aagtcatccg
    41941 agattttctc ctcattttca gagaaaatcc gaccaaggcc gtcactctca taacaaaaac
    42001 caaaggattt accagacaga ttaagccgaa taaaaggctt attttctagg gtgaaacttg
    42061 gctcagtatt gtaaagattc agttcctgac tgagttctgc aaaataatcc gtcgcagcct
    42121 gaggactttt tttctgatag agttctgcaa agtaggcatt aacaacactt ggcggaggtg
    42181 taataagtgt taactgctcc tgctctgttt taccagctag aagctgatcc agatagacct
    42241 tgtccagact tgtataacct ccatacttta gagccaaagt tttaatatca gtcataaaat
    42301 tcttctaacc tccatttatt tttctcggaa atgtagcctg taatcacttc gccgtcttcc
    42361 tgataatcac gttcttccag aattgcaaca ctctctaaat catgaatctt gtaggacttt
    42421 gaaaaaggca ctcgcagggt aaatgcttca aaaatttcct taatcttatc tagcaataat
    42481 gcttgcaagt tttcacgact gtcctcagac ttggcagaaa tgagggtata tggcgtttgg
    42541 gtaggcgtga aatcctccac caaatccgct ttattataaa gcgtcaagtg aggaatatct
    42601 tccatgtcca ggtctttcat gatggagaga accgtttttt catgctcctc gtggtaagga
    42661 ttgctagcat cgataacatg aaccagaagg tccacatgct tgctttcttc caaggttgac
    42721 ttgaaactgg acaccaactc tgtcggcaaa tcttggataa agccaacggt atctgtcaaa
    42781 gttacttgga gattgcctcc cagatgaata ctcttggttg tcgcatccag agtcgcaaag
    42841 agctcatctg cttcatactg ggtcttactg gtcaagatgt tcatgatagt tgatttccca
    42901 gcattagtat aaccaatcaa accaatctta aaagtgctag actccaaacg tttttctctg
    42961 acagtcgcac gatttttctc aaccaccttg agctggcgct cgatatccgt gatttgattg
    43021 cgaacgctac gacggttcag ctccagttgg ctttcaccag gaccacggga accaattccc
    43081 cctgcctgac ggctgagcat aatcccctga ccaaccaagc gaggcaagag gtatttgagt
    43141 tgggctaggt ggacttggag cttcccttca tggcttcgag cccgcatggc aaagatatcc
    43201 aaaatcaact gcatacggtc aatgacctta acaccgagaa cttcctctag attgacattc
    43261 tgccttgggg tcagacggtt gttgacgatg acagtagtga tttcttctgc atccaccata
    43321 agcgcaatct cttccaactt accagagccg acgaaggtct tggaatcata tttttcacgt
    43381 ttttgtctgt agctatctac aacgactgcc cctgccgttt tcgctaaact agccaattct
    43441 tccatggaga ggtcaaaact gtccataccc tgcaattcca caccaatcag caggactcgc
    43501 tcctcttttt tctccgtttc aatcatctaa aaactcctct atctggctta aaatgcggtc
    43561 ttgtacacca gattctccaa tctgataaaa ggtgacctgc atgcgattac ggaaccaggt
    43621 cagctgacgc ttggcaaaac gacgggtcgc ctgtttaaga ctctcacgag cttcctcaaa
    43681 ggtctgctct ccacggaaat aaggaaagag ttccttatag ccaattcctt tagcagcctg
    43741 tacattaggg gaatggtcaa acagccactt ggcctcatcc aaaagcccag cctcaaacat
    43801 caaatccact cggtggttga tacgctcata aagttgacta cgttcatcat ccaagcagat
    43861 aatcagcggt tcatacaaaa tctcttgatt ttccaaatcc tgaccaaaat gggcaatttc
    43921 taaggcacgc atagcacgac gacgattaaa ctggggaatc tcaaggcctg cttgctccac
    43981 caaatgggct aattcctcat ctgaatatgg ctccaaacta gctcgataag ctaaaatctc
    44041 ctcatgagga gtctccccac ctaggtggta accttctagc aagctctgga tataaagtcc
    44101 agtcccaccg acgataatgg ctagcttgcc acggctgtga atatcctcaa tagtcatctt
    44161 agcttctgaa acaaaatcaa aagccgagta agactcggtt atctctctaa catcgattaa
    44221 atgatgagga acagctgcct gctcttctgg actagccttg gccgtcccaa tatcaagtcc
    44281 tcgatagact tgttggctat ctccactaac cacttcgcca ttaaagcact ttgcaacttc
    44341 aatagctaga gccgtctttc caacagcagt cggtccaaca atcacaatta tttttgtttt
    44401 catctttttt ccttgaaaaa ttcccatttt ttcgttacta ttattataac acaaaaaggt
    44461 cagtcagaaa aatgtgacct cttgaggagg ctggctgatt gagaatataa aggaggaaga
    44521 ctcatggcta aaggattcgc taaaggtctt gtaacaggtg tcgcaggaac tgtcgctgcc
    44581 gttgcaggtg cagtatacgc atttaaaaag aaagtaatcg aaccagaaga gcaaaaagca
    44641 gctttcatcg aagaaaaccg taaaaaagca gctcgtcgcc gcgtatcacg ttaagaaaca
    44701 aaagaagttg ggattattct caacttcttt tttctattct tttaaatagc taggtcaaac
    44761 ttcaactgtg gcttaacagg gtcataatcc accaactcaa aatcttctgc tttgatatca
    44821 aagaaattag tcccatcagg aacatttaaa accaagcgtg gttggcagtt tgacggctcc
    44881 cgacggagca attcctgagc ttgttcaaat tgattatcat agatatggag gttgttgatg
    44941 aagtagaaga acttcccaac cttccagcca aaatgtttgg caatcatcat ctgcaaagcc
    45001 acatactgca tagcgttgat gtggtgggcc accagcatat cattggagcg ctgggtcaag
    45061 gtcgcatcca gatagatttc cccatcaaca cgccggacat caaacatggt ctgaaaggcg
    45121 cacgggagca gcccatctgt ttcttcgaaa gcttggtaat cccagagcga aataatattg
    45181 cggcggttcc aaggattggt ttccaactgt ttgagaagct tattgataat gtcgtgtttc
    45241 ttaacaacgg caccatagcg ctcaccaatg gttcccgtgt ctccaacttc ccagtcattc
    45301 cagtagtgaa cattgtactt gtcattaagc acttctaagc tatttgactg gtcttggtaa
    45361 atccagagaa cttctttgat ggcggatttg attgcaatgg gacgcaaggt tgtgatagga
    45421 aattctcctt tagataagtc gtactcggaa aaggcaccag ttacatactt ggaattagca
    45481 acagtcccat ccttgtactt aggacgagcc tgctctgaga aaacaccttc ctttagaatg
    45541 cgttcaatat tctctttaaa aatcgtatct gcttttgtca tttcgtttca cctcattcat
    45601 tgtcctaact agtatagcat aaaaaataaa agaggaacat tactaactct aggttagcat
    45661 tttcctctct cattatctta ttgcaataca agtgatgctg ctccgataac tccagcgtca
    45721 tttcctagag ttgcaagagc taatttagta gatgtgcgta cttgtgggaa actattttca
    45781 tcgtaaactt tttgaacacc ttgtagaagg aattctcccg cagctgacac accaccaccg
    45841 atgacgattg ttgatgggtt taggattgaa ccaatgttag cacaagcgat tcccaagtaa
    45901 cgtgagaagt tacggtaaac aatcaaagca aggtcgtctc cttcttttgc gagatcaaag
    45961 acagtcttag cagttacttc ttctccgtta tcaatcaagc gtttcaaggc tgcatcgcct
    46021 tcgtattcat cggcatagcg acgagtcaag ttgacaatcc ctgttgctga agcaactgtc
    46081 tcaaggcagc cttttttacc acaagtacat gagattggtt ggtcaaagtc aacagtgata
    46141 tgaccaagtt cacctgctgc accagcaaca ccatgaagca atttgccttc tgcgacaata
    46201 ccaccaccaa caccagtacc gagtgtcata aagacaacgt ctggttggtt atctccagca
    46261 cccatccagc gctcaccaag agctgctacg ttggcatcat tatcgatgaa aaatggaatg
    46321 cccaaagctt tttcaatctt ttgtttgatt ggttgaaggg ttttccagtt caagttgtag
    46381 gcaccgataa cagtcccttt ttcacggtca accacacctg gtgatcccat tccaatacct
    46441 tggaagtccg ctgctgccaa tccaagcaag tccaaacgat gttgaataga ctcaatcata
    46501 tcatcaacga tatgacttcc ctcatccaaa atgttggtct tgattgacca ttttccttgg
    46561 atttctcctg ctgttgttaa gattgcaaat ttgatagaag ttccaccaag gtcaatccca
    46621 ataatctttt gactcatcat attctccttt ttcattgtgt agtaattgaa aatgcttaca
    46681 gtactagtat atcaaaatcc attcacttat gcaaaggttt gcgtaaatga attataagga
    46741 attttttcgc ctaccagtat ctgttaacca tctaaatgat caatggcata ttgagctgca
    46801 tcatttgaaa atttatcaaa atcagaagtt aattgtctat acatacgttt ttttgacatg
    46861 tggaataacg aattataact ttttgccttt cctaaagcag cagaatattc actattgcta
    46921 tcattactag aagaagctgt acttgcttga ccttccttcc aaactccgtc agcgccaaca
    46981 taataacgtc caccatcaac ccattcattg acagccattt taccatccga ttttagatag
    47041 taatttcctt gccatgtact gtaagcataa gaaccatctg atgtcaaata ataccaagct
    47101 tgataggtgg catcataaac ccattcacct ttagccattt taccatctga tttcaaatag
    47161 tagtttcctt gccatgcatt gcgagcatat gaaccatctg atttcaagta ataccatgct
    47221 tggtaagaag aatcataaac ccactcacct tgtgccattt taccgtttga tttaaggtaa
    47281 taagctcctt gccatgtact gtaagcataa gaaccatctg atgtcaaata ataccaagct
    47341 tgataagaag agtcataaat ccattcactc tgtgccattt taccatcagc tttcaggtaa
    47401 tagtttccct gccatgcatt ttcactagat ttccatttcc atcaaaatag taccaagaac
    47461 cgtcctgctt aacccaacca cttgctgtgg atgaagttgt atcagtttga gttgtagccg
    47521 cttgttttgc tttaaaagca cccttaggag catttttcaa ttcgcaagcc acaccatcat
    47581 gatcgcggtc taacttggca gaataaccag gttctccctc atgaagatcc gaatatccat
    47641 tagcccaagc ttccttacaa ctcgaaaaat gaatgttttc ctctgctaac acaggttgtg
    47701 aaaacaaggc taaaattggc aacgtcacca gactcatttt taaaaataga cgtttattca
    47761 tttctttctc ccataattat gatatcgatt tcaatattat tttatcaaac ttatttcagc
    47821 aattcaagga aacttctggt cttttctaca aactcctttg gttttgcctt attcaagaca
    47881 tgagggccat ctgggataat ctgaaattgg gattctgata ttagtttatg aagacttctc
    47941 atagaactaa gattcggttt atctttgata ccacaaatta gtaaggttgg ataagggcaa
    48001 gttcctgcta tatccgttaa atcaagtgtc ttcaactcct cagaaactcc gaccataaga
    48061 gccttgtctg ctccctgttt ttcaaatact cttttgggaa gtagtttaaa aatcagcaac
    48121 tgaagataaa ataggatatt ccctgctaat ttaagcgggc atcctgacag aatcaaagct
    48181 cgaagatttg gtaaatcgta actggaaagt tctagtgcca gggcagcacc taaggacaat
    48241 ccaatcaaaa caaaaggttc tgtctcttga gctaggtgct gataaactcg ctccttagct
    48301 tgttgatagt tactaactcc agaaggaaat aactcgatag cctcagaagg ataatctgtc
    48361 agtagattcc gaacttcttt ccaagactct gctgactgcc ctaacccatg caaaaatatc
    48421 agtttcatct agttctcctc aaggcttagt tcatacaagc ctctcactgc attacagccg
    48481 taaatagctt ctgcttgggc taaatctgcc aaggtcaaga ctttctcttc tacctgtcct
    48541 gtttctagca aatactgacg gtaaattcct ggcaagattc caagtcggat aggcggtgtg
    48601 tagagttttc cagcgatttt cagaaccaaa tttcctatag aggtttcaag cagttttcct
    48661 gacttattgt ggtaaatctt ctcttgttct cctaggctca aatgcggtcg gtgagtggtt
    48721 ttaaagtagg taaaggattg attcaaagca gcttcctgaa ggcagacttg ggcctgacaa
    48781 aagcttgtac tgagaggggt taatacttga cgattgactt ctatctctcc agatttgcta
    48841 aggctgattc gcaagcggta atcttgatta gcttcacaat cctgacactc ttcctcaatc
    48901 ttgtgtccca agtcttctgc atcaaaagga aaggcaaaat aacgactagc ttttctcagt
    48961 ctttccagat gttgatcttc aaacagcagg ttcttctggc tgatttcccc tgtcgtaatc
    49021 agttggaagc gggcttgttt acgataaaga actgctgcct tttgatgaac ctctcggtat
    49081 tcagattccc atgtgctatc ccaagtaatc cctccgccaa ctccataaat ggcttgacct
    49141 ttgtgaagtt gaatggtacg aatggccaca ttaaaaatcc gtcgtccatt tggaagcaag
    49201 agaccaatcg ttccacagta gactccacgc ggttgaggct ccaagtcctt gataatctcc
    49261 attgtcgcaa ttttcggtgc acccgttatg gaaccacaag gaaagagtga gcggaagatt
    49321 tcaacaaggt ccacatcctc tcgcaactga ctcttgatgg tcgaagtcat ctgccaaaca
    49381 gttgaatact gctctacctg gcacagacgc tccacgtgct cgctcccaac ttcagaaata
    49441 cggttcatat cattgcgcaa gaggtccaca atcatcatat tttcagagcg atttttggga
    49501 tcctgttcca accaactggc ctgttcaaga tcttcttggt cagttacccc acgctgagtc
    49561 gtccccttca ttggtcgtgt tgtcaactcg cgatcatttt gctcaaaaaa gagctctggg
    49621 ctcatggaaa tcactgccat ctcgtcatgt tccacatagg cattgtagcc cgcctcctgc
    49681 tctaccacca tacgattgta gatggcaaaa ggattggcac ttaacttttg cttgagttgg
    49741 acggtgtagt tgacctgata ggtgtctccc tgcctcaagt gatggtgtat ctgggcaatg
    49801 gccttttcat agtctgctgc agacgtcact tcctgccaat ttgagggcaa atcaatatcc
    49861 tcataagtca gaggaatagg ggaggtctct accctatcat gaacagtaaa gtaaagcagg
    49921 tactctccca gtaggggatc cttgtgaact gctaattttt cctcaaaagc aggggcagcc
    49981 tcgtagctga cataccccac cacataataa ccttgctctt ggtagctttc cacttgtgcc
    50041 agcaaatctg ccacttctgc tacatttctc gtttttatct ctttgatagg ctgggtaaag
    50101 gtgtatctct cccccaaaat cctaaaatca atcactgttt ttctatgcat accttaagta
    50161 tagcataaaa taagaaaacc ctcatccgca aagcagatga gagatttcaa ttatttaaag
    50221 attgaagttt taaagctatt tgtttgttga agaagtttct tataaacttt ttcttttact
    50281 tgcacaagtt taccattaac tttattagta accatatctt cttcaagagc tttggcaaat
    50341 aatgatttta attcatcata gttatgaatg gtctcaccat caatagtaaa aggagtaaaa
    50401 ccagcgttgg ctttttctaa caattcttta taatattctt tcttaaaatc agcaaacgat
    50461 tggaatctgc cgtcagatat tttttgtata atatattgat ctccaaattg tttcccttct
    50521 ttattagctt gagattttaa tttatctgaa gcatatccta agaatccttt atcatagcca
    50581 taatatcccc agagtctaaa tgcattattc ttaaatgtaa cagcaccggg tgcaccctca
    50641 cttgtgttac ctgcatagat actattcatc attttaattc ctacataggc aatacctgga
    50701 tcaaatactt ctggcttata tatattatta ttcatcatac gattagtcat cagattatta
    50761 tcaactaagt cattaacact gtttaatgtt attcctttcc aatcatcaga gctcatattt
    50821 cgaaccttgt catattgatc ttttgaccct acagtgcgtt caataggatc aactttctta
    50881 aaccacagtt gatttaattt atcatcatgt ttactaatga ctgcatcacc ttcaacataa
    50941 tcaagaagag acaaggtatc tatatagcct ttcatataat tatcaatgtc ttctcttgtt
    51001 ttaagagtct tcggatcggt aatataccac tgatttccat catttggacg atagaaagtc
    51061 atattaattc ccaaagcacc gtattcatca aaccatgtac ttggtactgg tgtttgtaac
    51121 attccttgtg cataggcttc tgcatgagtc cctgagcgac gtccatatcc tcctaaatag
    51181 attgcacgat cattaacatg agtagtttca tgtgtataaa cagagattcc aaactcatca
    51241 atcatactta atgcaatata atttacttct gttcgcgtat ccaaaggatt atcccaaata
    51301 actgcataag cacctgttcc attgttacca taatacttac caataggtcc aaacaactct
    51361 ctcaatgggg catagtcttc tttattattt ctcttaccat acttatcagg ccatccacca
    51421 ggtgcttgat aaccttccca aagaggagtt actgtatttt tgactagcat attcttaacc
    51481 ttatctaaag ataatctata ccaaaaatca aaataatttc gataactgtc cgctgctttt
    51541 tcaatctgat tttttattcc atcgaaggag ctatgcccta acttttctgc tgttccaaca
    51601 gccattgcac tataattcga gattaaatac acatgtgatt tatttagatt taataatggg
    51661 agtatcatct tccgatgagt agcagattgt aaattatccc aaactttata tttcgccgct
    51721 ttaatttcat cgacttccga agcacgctcc gctatataga cattcccttc tgtagctttc
    51781 ttaaaccaat cataaatatt tacatctgca gtaaatagtc gacgattata atttaaaaag
    51841 tttaccaaat tttctgataa ggttgtctta gaaataatct cgctgaaagc atcatatgtc
    51901 cgatgacctt ttatattatc ttctcttgaa ccgatttcaa ttaatctatc taatacactt
    51961 acatttttac catagaaatc tggtttgaat aacattaatt ctttaatgtt aacatcaccg
    52021 aatttaacac cgtagtaacg gtttaagtat gttaaaccta ataatagggc agctttattt
    52081 ttctcaactt tatcaagaat catttgttga gctgcagatg aattattcag ttgatgatct
    52141 tcattttcaa ctaatttagt tactaatatg tttaaattag cttttacatg gtcaaaactt
    52201 tcttctaaat aaaggtcttt aattgcattt actctattag accctgttct gccaagtttt
    52261 tggtaaattg gattagattg aagctcaata gggcttaaga tatttacgat accgttaatt
    52321 aaagcactat gatctttttg aacgatatta ggtgtatatt taatacctaa gtcagttata
    52381 gtgtattctc taacattact tagaccttca tcactagaag ataggttgaa gtagtctttt
    52441 gttccatcag cataatgaac gataattttg tttgcatcac ctaaatcagt tacaaagtta
    52501 ttattgttca taggagtaac cgatagaatc tctttagtat ttaacttgtt gttcttatct
    52561 agtttattag cttgattaac gataaaatct ttgttataga atggttgtag tttttcaata
    52621 ttcttataag caagtttata gtctgcatta taatcttgaa tagactcgta agctgcttca
    52681 cgactgctaa cattattcaa tttgttcaat tcataaggtt cacttacgaa tttagcagca
    52741 gtaatattga aactagcaac ttttgcatca gcctcagatt tagataagtg ttttaattta
    52801 tttttgtttt tattatcttt accagttcca tcttcagaag agctatatcc aataactcca
    52861 aataaattag acacaaaagg atttgcatct ccatcattaa catcgtttga accgaatatt
    52921 tcctgacctt taataacttt cgcatatgtt acattatctt gaaccgctcc atatggccaa
    52981 gttttagagg ttattccacc aacatattta gtatttttaa catcaagaat accttttgct
    53041 acagagtttg taagttttcc ttttgtccct gatagccagc tatgagcttt atattgaacg
    53101 aaaggaacaa gcatacttgc atttgcgtta tttgctgtaa tagtagcatc aacgtaggct
    53161 ctattaacaa accccatata gttagaaccg gcaatacctc caactgttga attattacca
    53221 gcagaattta tactaccgat aaatgccaca ttttctaaag tagcgtcttc ttttatgtta
    53281 tttacgaacc cagcaacatt atttctagct gttatggttc cgattgcttt gatattttct
    53341 atacgtgtcg ttccactgat ttcatttgct attgcagcga tattatcttg attagataaa
    53401 tcaatatcaa tattttcaaa atttatattt ttaacagttc cagccttaat cttatcgaat
    53461 aaaggatgtt ccaaattatg gatagcatag cgtttatcac catcactcaa tagtttacca
    53521 gtaaactctg aagtaatata agatttccct ttaggaacaa cgttacgagc gctcatgctt
    53581 tgacccagtt taaattcacc ggcaggattt gtctgaatgg cttggatcaa ttcttcaaag
    53641 tcgtagaaaa taccagcctg actagctttg ggtttttcaa tatagtaggt ataagtttct
    53701 tcaaagcgat tatcgacatt acgttggacc aagttatccg ctactgctat taccttgtag
    53761 acttgttttc catcaattgt tgactcttca attttttgaa ccgctagtag attggtctta
    53821 tggtcattag aggtaacttt taaataataa tttgacaaat cagttggcac tgaagtcaat
    53881 cgagtttcat cagtttcaac ttggttttca tatttgatta aatccgttct tataatatct
    53941 tttatttcaa cttttttgag atcaattctt agcggttctt ctttcagaac ttcttcctca
    54001 tccccctcac cacggtcata aaccatcttt gtttcaagtt tataatcctt gtagtactgc
    54061 aaatctgtca gggtagttgt caagtcttct ggtgaaacat tcaaggtttt gacaatctca
    54121 tcaccttttt tcagagttag ggtaatagat ttaatggctg ccttacttgg attttctaaa
    54181 ctatacttaa catctgaagt acgcttcaaa tccttagatt caatttctgt gatggtcaac
    54241 actggttttt caaagctctt ggtaccacgt ttcaaaattt tgtcttgagg ttcctcaagg
    54301 atttcctctg taacttttgg agcgtcttct gttttaactc ccttaatggt attaaaggtc
    54361 ttggtgattt ttttctggcc ttcttttcct tcttgagcta caacttctaa gccttttttc
    54421 agttggtcat cttctttaac aacttcctta aatggaatct tttcaagact ttcttctata
    54481 agagttcctt caattggttt tgtaccacgg attacctgtt gatttacagg ctccttggtc
    54541 acttccgtac tggttgaaag aacttggtca gttttaacac cttctactgt tttataggtt
    54601 gtttttgtaa cttgacttcc tttttcacca gttcgtagga cagtttcttc gtccgtatac
    54661 ttggttggat cctcagtcgt ttcagttttg tagtctaggt ctgtagtcga tgtttcaaca
    54721 agggttccct cagttacttt gtactcaggt aattgttctt gagcaagagc ctcacccacg
    54781 tgaccttttt cttgcgtacc tttagctgtt ttagtctcct cttttgattc tactggttct
    54841 tcaaccttga tttctggggc ttctgctggc tgttcatctt cttgtttcgg tgtctcttcc
    54901 gctcccctat cttctttagg attttcttgt tgtgatgatt cttttggtgt acttggttgc
    54961 tcagcttgtg taggttgcac gggttgttct gggacttttg cttgttctac tggtggttca
    55021 acttttgatt cctcagctgg tttgtctgat ggttgacttt ctggcttaac tgctactttt
    55081 tcctctggtt ttgactcaac ttctccacct acttcttcaa ctggagctgg ttctgctgaa
    55141 tcttctttcc cctcttctac tttaggaagg gtgtcgtcag taggttttac ctccgatttt
    55201 ggttcttcct ttggactttc ttctgtttta ggtgcttctt cttttggagc ttcctctgtc
    55261 tctactactt ggttttctgt cctagcttgc tcctgatttg ttgttgattg aggagtctca
    55321 acttcgacta cagtcacctc tccaggtttt gctgaggttt cttctaaaac agtgtccaag
    55381 ccaagcgttt tgaggatgtc acctgataga taaccaacat agcgatagcc atccatttca
    55441 acaacaccct ctcgactagc cagcgctagg gtcgcaactg ggtctacagc ccctgcacta
    55501 ggaagaacta ccaatcccat agctccaact agaaagacgc tagcaatttt ctttctcttg
    55561 tagattaaaa gcaagctccc aacagtcagc aaaccaaaag ctgtcaaaac agatgcttct
    55621 gtccctgttt gaggaaactg atctttttga tacaccaaac catatacaac ttcattcctg
    55681 tcaggctttc ctgtctgaat taaatcttta gcttcttgtg aaataatctc tttatttaca
    55741 tagtgatagg tggctgcgtc cactacagaa ggagccatca aaaggcttcc aagaaataca
    55801 gagcctacaa ctcccttaat cttacgaatt gaaaaacggt cttttttaaa cacttttatc
    55861 tcctttattc attctcaaga ctttctaata gcatcttgcg gatagtgcgc acgcgcacct
    55921 ccgattaatt ttggacgact agccagtgcc gttacatggg catgaccaat ctctctcaaa
    55981 atagggcgaa tcggaacctg aacatgcttg acatgcatgc caattgcagt gtctccgata
    56041 tccaatccag catgagcctt gataaattca acctcaactg gatcctgcat aaacttaaag
    56101 gctgccaact gccccgaacc tcctgcatga agagtaggat ggacactgac aatttccaga
    56161 tcaaactgct ctgccacctg acgttcaaca acgagagccc gattgacatg ctcacaacct
    56221 tgaactgcta aatggatacc tctactacct agaataccca agatagtctc cactatcagc
    56281 tcaccaatct cttgactgga ttctttccca atctgaccac ctagcacctc actagaagat
    56341 agacctaaaa caaaaaggac cccctgcttc aaattggtct tttctaaaac atcttccact
    56401 acctgacgtg tttctctttg aatctgtgtc tcgttcatct ctgttacctc tgttgttact
    56461 cttctatcat accgtttttt cttgttttta gcaagataga caacctagaa agcttgccca
    56521 attacgcata aaactcccag aattgactgg gagttagcta gtttctattc tatttatata
    56581 tatttcaact ttcgtccctt tttggggtct agaatcaatc ttcatctggt aattggctcc
    56641 aaaatgaagt ttgagccgtt gatcgacatt ttgaagacca actcccccac gtttgagttg
    56701 actttgacta ctatcaccag catcttggaa gccaacgcca tcatcctcaa tacggatgac
    56761 caatcccgaa tcctgtttct ggacagaaag tttaatatgg ccctgacctt ccttttcctt
    56821 aatgccatgg taaagagcat tttctacaag gggttgtagg accagcttgg gtaagactaa
    56881 attatcaaag gcaacatttt cattaatttc gtattccagc ttatctccat agcgttgttt
    56941 ctggataaag agatactggc ggacatgatt gatttcgtca gagagacaaa tcaagtcttt
    57001 gccttgattg agcgccaagc ggaaataggt tgccaaggac ttggtcacct gcaccactcg
    57061 ctgactatca tgaaattcag ccatccagat gatggtgtcc aaagtgttat agaggaaatg
    57121 tggattaatc tggctcgaaa gggcttgaag ttggtactga cgggtcgttt cttcctggct
    57181 acgaatagct accatcaact gatcaatctg atccaacatg gcattaaatt ggcgagttac
    57241 ttctctcagt tcataggcac caacttcctt ggcacgaaga ttttgagcac cagaagcaat
    57301 ttccaacatg gtttctctca aatccttcaa aggagcaatc cagcgtttaa gactgaacca
    57361 cactaagcag agacaaacaa gaagagatgt gacactggcc ccaagcaagg tccacaagag
    57421 ctgactccga acctggtcta acttttccaa tgatgacacg ccaagtaccg tccaatcagt
    57481 tcctgcaatc ttctcttgac tgacgtagga tttgtgacca ggagtataac cctgacctgt
    57541 ctcgatgtag ggtttcatag cctccatttt gctagacgaa ctataaactg tgtgttgagg
    57601 atggtagaca aattcatggt tttcattgat aatgaaggca aagccctgct gccccaactg
    57661 gagttgattg agataggctt ccagagtttc ataagaaata tccaaacgaa gcacaccaag
    57721 attggctccc tttgcatcaa caagttcttg agtgacagaa atgacccact gactatctga
    57781 tttacgagct ggagtcaaaa caggcatagc tccctgatga atagcctttt ggtaccaatc
    57841 ctcagccatc atatcagagg aagttttcat ctgcacactg tcatctgtag aaatgacctg
    57901 accagatttg gtcaccagca caacagtttt caagtcctta tctgacttca agatggtcaa
    57961 aaacaaatct cggattccct cgaccttgtc ttgactggga ttctcagcat aggccagaac
    58021 atccgtctgc tgggtcaaac cagtcgaggt ggtttctagt tttttgatat aagactgaat
    58081 aaagtggcta gtctggctga tggtcgtttg gctgttgccc tcaatggtgg cctcaatggc
    58141 tgaagaactt gattgatagt agaaagttcc aaccagagct aggagaatga gaaagaccag
    58201 aaagatggaa ataaccattc taactaaaag agaagaacgc ttcatcggtc ttctcccttc
    58261 ttaaactgac gaggtgtcac acctgcaatc tgcttaaaac gttgggtaaa atagttcata
    58321 tcttcaaaac caaccttctc tgcgatctca taaatcttca gatctgtagt taaaagcaag
    58381 agcttggctt gtttaacacg ttctctcacc agataatcct gaaaaggcaa gcccaactct
    58441 ttcttaatca aggaactcag ataggtcgga ctaaaaccta agtcactggc taaagacttt
    58501 aaactaaatt ggctatcagc cagatgagac tggattttct gggccatgtt tccttcaaac
    58561 ctattagtca ataaatcttg taactgctct tctttctctt ccttgtctag tttttgtttg
    58621 attttcccca acatttcctc aatatcctga cgagaaaagg gtttgagcag gtagtcgtcc
    58681 acacctagtt tgacagcaga caaggcataa tcaaaatcat cgtaacctgt taaaaagacc
    58741 aaatgaacct gaggataggt ttctcgtacc agactggcca actggatgcc atttagatga
    58801 ggcatgttga tatcggttaa aatgatatct ggcacctgct tttggatcaa ttcccaagcc
    58861 tgccttccat tttcagcctg accgatgatt tccatatcgt aggctgctac attgaccagt
    58921 ttagtcaaac cttgtcttac cagatattca tcttctacga ttaagattgt gtaggtcatg
    58981 ctctgctcct ttaccactta ctagtatcag tatagcaaaa ttctcctcta actgcttagg
    59041 aaagacctct tatactcaat aaaaatcaaa aagtaaacta ggaagatagc cacaggtttc
    59101 tcaaagtata gctttgaggt tgta
//
LOCUS       DAVBNN010000007        49773 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBNN010000007 DAVBNN010000000
VERSION     DAVBNN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.007"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            449..637
                     /locus_tag="VQ847_000402"
                     /pseudo
     CDS             449..637
                     /locus_tag="VQ847_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1052..1669
                     /locus_tag="VQ847_000403"
     CDS             1052..1669
                     /locus_tag="VQ847_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3049801.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(1712..2599)
                     /locus_tag="VQ847_000404"
     CDS             complement(1712..2599)
                     /locus_tag="VQ847_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3049802.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(2748..4631)
                     /locus_tag="VQ847_000405"
     CDS             complement(2748..4631)
                     /locus_tag="VQ847_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3049803.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            5007..6461
                     /locus_tag="VQ847_000406"
     CDS             5007..6461
                     /locus_tag="VQ847_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3049804.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            6442..7407
                     /locus_tag="VQ847_000407"
     CDS             6442..7407
                     /locus_tag="VQ847_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3049805.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(7442..8716)
                     /locus_tag="VQ847_000408"
     CDS             complement(7442..8716)
                     /locus_tag="VQ847_000408"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3049806.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMAILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VVLSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(8716..9888)
                     /locus_tag="VQ847_000409"
     CDS             complement(8716..9888)
                     /locus_tag="VQ847_000409"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3049807.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(10019..10267)
                     /locus_tag="VQ847_000410"
     CDS             complement(10019..10267)
                     /locus_tag="VQ847_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049808.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(10335..10939)
                     /locus_tag="VQ847_000411"
                     /pseudo
     CDS             complement(10335..10939)
                     /locus_tag="VQ847_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11001..11450)
                     /locus_tag="VQ847_000412"
     CDS             complement(11001..11450)
                     /locus_tag="VQ847_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3049809.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(11452..12210)
                     /locus_tag="VQ847_000413"
     CDS             complement(11452..12210)
                     /locus_tag="VQ847_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3049810.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(12325..14304)
                     /gene="pknB"
                     /locus_tag="VQ847_000414"
     CDS             complement(12325..14304)
                     /gene="pknB"
                     /locus_tag="VQ847_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3049811.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(14301..15041)
                     /locus_tag="VQ847_000415"
     CDS             complement(14301..15041)
                     /locus_tag="VQ847_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3049812.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(15056..16369)
                     /gene="rsmB"
                     /locus_tag="VQ847_000416"
     CDS             complement(15056..16369)
                     /gene="rsmB"
                     /locus_tag="VQ847_000416"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3049813.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(16362..17297)
                     /locus_tag="VQ847_000417"
     CDS             complement(16362..17297)
                     /locus_tag="VQ847_000417"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3049814.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(17310..19706)
                     /locus_tag="VQ847_000418"
     CDS             complement(17310..19706)
                     /locus_tag="VQ847_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3049815.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(19772..20086)
                     /locus_tag="VQ847_000419"
     CDS             complement(19772..20086)
                     /locus_tag="VQ847_000419"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3049816.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(20111..20737)
                     /gene="gmk"
                     /locus_tag="VQ847_000420"
     CDS             complement(20111..20737)
                     /gene="gmk"
                     /locus_tag="VQ847_000420"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3049817.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(20867..22480)
                     /locus_tag="VQ847_000421"
     CDS             complement(20867..22480)
                     /locus_tag="VQ847_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3049818.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(22823..25570)
                     /locus_tag="VQ847_000422"
     CDS             complement(22823..25570)
                     /locus_tag="VQ847_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3049819.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            complement(25917..27014)
                     /locus_tag="VQ847_000423"
     CDS             complement(25917..27014)
                     /locus_tag="VQ847_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3049820.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(27024..27770)
                     /locus_tag="VQ847_000424"
     CDS             complement(27024..27770)
                     /locus_tag="VQ847_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3049821.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(27873..28226)
                     /gene="rsfS"
                     /locus_tag="VQ847_000425"
     CDS             complement(27873..28226)
                     /gene="rsfS"
                     /locus_tag="VQ847_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3049822.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(28239..28739)
                     /locus_tag="VQ847_000426"
     CDS             complement(28239..28739)
                     /locus_tag="VQ847_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3049823.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            complement(28740..29333)
                     /gene="yqeK"
                     /locus_tag="VQ847_000427"
     CDS             complement(28740..29333)
                     /gene="yqeK"
                     /locus_tag="VQ847_000427"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3049824.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(29333..29962)
                     /locus_tag="VQ847_000428"
     CDS             complement(29333..29962)
                     /locus_tag="VQ847_000428"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3049825.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(30014..30325)
                     /gene="yhbY"
                     /locus_tag="VQ847_000429"
     CDS             complement(30014..30325)
                     /gene="yhbY"
                     /locus_tag="VQ847_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3049826.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(30539..31645)
                     /gene="yqeH"
                     /locus_tag="VQ847_000430"
     CDS             complement(30539..31645)
                     /gene="yqeH"
                     /locus_tag="VQ847_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3049827.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(31648..32238)
                     /locus_tag="VQ847_000431"
     CDS             complement(31648..32238)
                     /locus_tag="VQ847_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3049828.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(32190..33098)
                     /locus_tag="VQ847_000432"
     CDS             complement(32190..33098)
                     /locus_tag="VQ847_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3049829.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(33155..33715)
                     /locus_tag="VQ847_000433"
     CDS             complement(33155..33715)
                     /locus_tag="VQ847_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3049830.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            33854..35062
                     /gene="sstT"
                     /locus_tag="VQ847_000434"
                     /pseudo
     CDS             33854..35062
                     /gene="sstT"
                     /locus_tag="VQ847_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            35130..36083
                     /locus_tag="VQ847_000435"
     CDS             35130..36083
                     /locus_tag="VQ847_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3049831.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREARTFIQVKVDFYQKYRQ"
     gene            36226..36606
                     /locus_tag="VQ847_000436"
     CDS             36226..36606
                     /locus_tag="VQ847_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3049832.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            36705..36926
                     /locus_tag="VQ847_000437"
     CDS             36705..36926
                     /locus_tag="VQ847_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3049833.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            36943..37257
                     /gene="trxA"
                     /locus_tag="VQ847_000438"
     CDS             36943..37257
                     /gene="trxA"
                     /locus_tag="VQ847_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3049834.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            37562..38095
                     /gene="queF"
                     /locus_tag="VQ847_000439"
     CDS             37562..38095
                     /gene="queF"
                     /locus_tag="VQ847_000439"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3049835.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(38349..39017)
                     /locus_tag="VQ847_000440"
     CDS             complement(38349..39017)
                     /locus_tag="VQ847_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3049836.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(39128..39919)
                     /locus_tag="VQ847_000441"
     CDS             complement(39128..39919)
                     /locus_tag="VQ847_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3049837.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(40343..41107)
                     /locus_tag="VQ847_000442"
     CDS             complement(40343..41107)
                     /locus_tag="VQ847_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3049838.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(41100..41870)
                     /locus_tag="VQ847_000443"
     CDS             complement(41100..41870)
                     /locus_tag="VQ847_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049839.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            42117..42794
                     /locus_tag="VQ847_000444"
     CDS             42117..42794
                     /locus_tag="VQ847_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3049840.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            complement(42854..44650)
                     /gene="pepF"
                     /locus_tag="VQ847_000445"
     CDS             complement(42854..44650)
                     /gene="pepF"
                     /locus_tag="VQ847_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3049841.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(44661..45404)
                     /locus_tag="VQ847_000446"
     CDS             complement(44661..45404)
                     /locus_tag="VQ847_000446"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3049842.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(45406..46359)
                     /locus_tag="VQ847_000447"
     CDS             complement(45406..46359)
                     /locus_tag="VQ847_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3049843.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            complement(46494..46922)
                     /locus_tag="VQ847_000448"
     CDS             complement(46494..46922)
                     /locus_tag="VQ847_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3049844.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(46903..47991)
                     /locus_tag="VQ847_000449"
                     /pseudo
     CDS             complement(46903..47991)
                     /locus_tag="VQ847_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
     gene            complement(48010..48480)
                     /locus_tag="VQ847_000450"
     CDS             complement(48010..48480)
                     /locus_tag="VQ847_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3049845.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(48771..49223)
                     /locus_tag="VQ847_000451"
     CDS             complement(48771..49223)
                     /locus_tag="VQ847_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3049846.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(49260..49438)
                     /locus_tag="VQ847_000452"
                     /pseudo
     CDS             complement(49260..49438)
                     /locus_tag="VQ847_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            complement(49575..49754)
                     /locus_tag="VQ847_000453"
     CDS             complement(49575..49754)
                     /locus_tag="VQ847_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049847.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
BASE COUNT        14365 a        11250 c         9280 g        14878 t
ORIGIN      
        1 atatctacgg caaggcgaag ctgacgtggt ttgaagagat tttcgaagag tattagtgat
       61 aaatccatta tacagcagca aacttaattt ataccttccg ctcctcaact gtctattttt
      121 aatcctgaat tgttatttga gtaactcctt tttcctcgta aagttttctt cctctaaaac
      181 ttctggaaaa aggctaatag tttcagacaa catttttata agaaacaagt tcatctgtca
      241 tttcaagaag gagtaatcct ttatctacta atggacggaa cagaattcaa ccgcttgtcc
      301 catatgtttt ctaaggatta tatagtaaaa tgaaataaga acaggacaaa ttgatcagga
      361 cagtcaaatt gatttctaac aatgttttag aagtagatgt atactattct agtttcaatc
      421 tgctatatct attatgcaca cccctatagg atctaatgaa aatcacaaca ggctcattca
      481 tagatagtta cctcaggaaa ctaagaaaac gactacaaag gaagtcgcat tcatcgaaaa
      541 gtggattaac aactatccta aaaaatgctt gaactacaag tcccccagag aagacttctg
      601 gatgactaac ttgaacttga aatttagcaa taattaattc accatctaac tatatttagt
      661 aattatttca gaactgatta atattaaaat taactaacaa ttcaaaggat tcatactagc
      721 cataaattac gtccatcaga gagagactct tactactttt agattttagt ctttctagct
      781 tcagaataca tctaaacttt agggaaaatg actattcgaa agcgcgaatg cctcaaaatt
      841 atctcagata agctattcga aacttagaat gcttttaaat ttatggaatt gcgattattt
      901 gaaacctaga atgcatataa cctttagttg acagacctat tctaagtctc gaagggctat
      961 ttactttcta ttccttatca aaaaagactc attccccctt tctcctccaa aatatggtat
     1021 agtagaaata tactatctat gaggagttta catgtcacag gataaacaaa tgaaagctgt
     1081 ttctcccctt ttgcagcgag ttatcaatat ctcatcgatt gtcggtgggg ttgggagttt
     1141 gattttctgt atttgggctt atcaggctgg gattttacaa tccaaggaaa ccctctctgc
     1201 ctttatccag caggcaggca tctggggtcc acctctcttt atctttttac agattttaca
     1261 gactgtcgtc cctatcattc caggggcctt gacctcggtg gctggggtct ttatctacgg
     1321 gcacatcatc gggactatct acaactatat cggcatcgtg attggctgtg ccattatctt
     1381 ttatctagtg cgcctatacg gagctgcctt tgtccagtct gtcgtcagca agcgcaccta
     1441 cgacaagtac atcggctggc tagataaggg caatcgtttt gaccgcttct ttatttttat
     1501 gatgatttgg cccattagcc cagctgactt tctctgtatg ctggctgccc tgaccaagat
     1561 gagtttcaag cgctacatga ccatcatcat tctgaccaaa ccctttaccc tcgtggttta
     1621 tacctacggt ctgacctata ttattgactt tttctggcaa atgctttgac acgtaaaaaa
     1681 tccgtttggt ttcccaagcg gattttgtgc tttattttga aacttctttt gcaagaacaa
     1741 agttcccaag tgtggcagaa ccatttcctg cgactgctgg cgtcacgata tagtcacgca
     1801 catctggtac tggtaggtaa ccattaagaa gagatgtaaa tttctcacgg acacggtcca
     1861 gcatatgttg ttgagccatg acccctccac caaagacaat cacgtctggg cggaaagtca
     1921 ctgtcgcatt aaccgcagct tgagcgatat agtaggcttg aacatcccaa acagggttgt
     1981 tgagttcaat agtttcccca cgtacacctg tacgagcttc caaacttgga ccagctgcat
     2041 agccttccag acatccctta tggaaaggac aaacaccctt aaactctttt tcaatatcca
     2101 ttgggtgtct agcaacataa taatgaccca tttcagggtg acccacacca ccgataaact
     2161 caccacgttg gatgacgcct gcaccgatac ctgtaccgat tgtgtagtaa accaagtttt
     2221 cgatacgacc accagcattg ttacgggcaa ccacttcacc gtaagcagag ctgtttacgt
     2281 ctgttgtgaa gtacattggc acgtttaggg cgcgacgaag ggcaccaagc aagtccacat
     2341 ttgcccagtt tggttttgga gtcgtcgtga taaagccata agtttttgag tttttgtcaa
     2401 tatcaatcgg cccaaatgaa ccaactgcaa gaccagcaag gttatcgaat tttgagaaga
     2461 actcaatggt tttatcgatt gtttcgattg gagttgttgt tggaaattgt gttttttcta
     2521 caacgttaaa gttttcatca ccaacagcac agacaaactt tgtaccgcca gcttccaagc
     2581 ttccatataa ttttgtcatg ataaacctct tgtttttatt ttctttatta tagcatactt
     2641 cgaaagtcta aatgtctcta ttttttagat tttcctctgt aaatcttact atctaataaa
     2701 aacgaacaaa catgtcattt gttcgttttc acattagaga ggattgatta gattttcact
     2761 tcgatcacag catccccctt cgcaactgaa cctgttgcga ctggagctac tgaagcgtag
     2821 tcagctgtat ttgtaacgat aaccattgtt gtatcatcaa gtccagctgt agcgatttta
     2881 tttgagtcaa atgttccaag aacatcgcca actttcacct tatcaccttg agcaactttt
     2941 gcttcaaaac cgtcaccgtt catagataca gtgtcaatac caacatgaat caaaacttca
     3001 gcaccatttc ttgttttcaa accaaaagcg tgccctgttg gaaaggcaat tgaaacttca
     3061 gcatcagctg gtgcatagac cacgccttgg cttggtttca cagcgatacc ttgtcccata
     3121 gctccacttg agaagactgg gtcattgaca tcagcaagag cgacaacatc accgacgata
     3181 ggagttacaa gtgtttcatt ttgaagagct gctggcgcaa cttcttcttt ttcttcagcc
     3241 acttcagctt gttttgcagc tgcagttgcg tctacttcat cttcgtaacc aaacatgtaa
     3301 gtaagagcaa aaccaagggc aaatgataca gctaccataa gaaggtattg tggaagttgt
     3361 ccgttaccaa cataaagcat tgtaccaggg atgatggtga taccattacc agtaccagca
     3421 agtccaagga tagaagccaa tccaccaccg attgcaccag caatcaatga aaggaagaat
     3481 ggtttacgga agcgcaagtt caccccgaag atagcaggct ctgtaatacc taggaaggca
     3541 gaaagagcag ccgggaaagc aagtgttttc agttttggat tttttgtttt aacaccaacc
     3601 gcaacagtag cagcaccttg agctgtcata gcagctgtga tgatagcgtt gaatgggtta
     3661 gcatggtcag cagcaagtaa ttgcacttca agcaagttga agatgtggtg cacacctgac
     3721 acgacgatca attggtgaac cccaccaatc aagaaaccac caagaccaaa tggcatgcta
     3781 agaatcgctt ttgtagcaat aaggatgtag ttttcaacaa cgtggaaaac tggtccaatg
     3841 acaaagagtc caaggataga catgaccaaa agtgtcacga atggtgttac caagaggtca
     3901 atgacatctg gaacaacctt gcggacagct ttttcaaatt tagctccgac aaccccgatg
     3961 atgaaggctg gaagaacgga accttgcaaa ccaacaacag ggatgaaacc aaaaaagttc
     4021 atcgctgtta cttcaccacc ttgagcaact gcccaagcgt ttggaagtga gccagagaca
     4081 agcatcatac caagaacgat accaacggca ggatttccac caaatacacg gaaggttgac
     4141 cacacaacca aacctggcaa gatgatgaag gctgtatctg tcaagatttg tgtgtaagtt
     4201 gcaaagtcac ctggaagtgg catttcaaga gcgttgaaaa gaccacgcac acccatgaag
     4261 agacctgtcg ctacgataac tgggatgatt ggaacgaaaa catcaccaaa agtacggata
     4321 gcacgttgga accagttccc ttgtttagca acttctgctt tcatgtcatc cttagatgat
     4381 gttggtaatc caagtacaac aacttcatcg tacattttgt taactgtacc tgtaccaaag
     4441 ataatttggt attgccctga gttaaagaaa gcaccttgaa ctttttccaa gttctcaatc
     4501 acttctttat tgattttctc ttcatctttg accatgacac gtagacgagt cgcacagtgg
     4561 gcaacactat tgacattttc acgtccgccc aaggcatcga tgactttttt tgcaatttcc
     4621 tgattgttca tttgcaaaaa tctccttata taacattttg ttcttgtttg aaagcgattt
     4681 tattcgccct tacgactatt attttatcat gttttaaaaa tatgtcaagc gttttgcata
     4741 aaaatattct atccacttag tgggcaagct ttagattgat tgtttttgac tgtttcatca
     4801 ggaattcctt gaaaaataag tttgaaacct tggttaaaaa gtattttatt tcattatctt
     4861 tcacattttc gtaaaaattt gattgatttc ctgtatttat tttatgataa tcgtttgaca
     4921 gtttttcctc ttttttaaca taaaaggctt gcatttttta tcgaaaacag ttactattaa
     4981 aagtgataag atttttggag gaatgaatgg aatggacaac tgagcgtcgt tacagacttt
     5041 atcaagattg gacgcaagaa gaaattcaac atataaagga aaatatggca caatctccat
     5101 ggcatactca ttaccatgtt gagccaaaaa caggacttct caacgaccca aatggctttt
     5161 cttactttga tggcaagtgg atcctctttt accagaattt tccttttggt gcagcccacg
     5221 gtttgaaatc ttgggcacag ctagaaagtg atgatttggt tcactttaaa gaaactggaa
     5281 tcaaagtttt accagatact ccattagata gccacggtgc ctactctggt tctgccatgc
     5341 aatttggcga taacttattc ctattttata caggaaatgt tcgcgatgaa aactggatcc
     5401 gtcacccata ccagatcggt gctttgatgg acaaggaggg taagattaca aagattgaca
     5461 agatcttgat tgaccagcca gcagactcta ctgaccactt ccgcgatcca caaattttta
     5521 actttaaagg tcaatactat gctgtcgtcg gtggacagga cttggagaaa aaaggcttcg
     5581 tccgtctcta caaggctgtc aataacgact acacaaactg gcaagcagtt ggcgaccttg
     5641 actttgctaa cgaccgtact gcctacatga tggaatgtcc taatctgatc tttgtagagg
     5701 aacagcctgt ccttctctac tgtccacaag gattggataa gaaagttcta gactacgata
     5761 atatctttcc aaatatgtat aagattgggg cttcctttga ccctaaaaat gccaaaatgg
     5821 tagatgtgtc tcaacttcaa aacatggatt acggtttcga agcctatgca actcaagcct
     5881 tcaacgctcc tgatgggcgt gctctagcag ttagctggct tggtttgcca gatgtttctt
     5941 acccatctga ctgttttgat caccaaggaa ccttctcttt ggtcaaggaa ctcactatca
     6001 aagacgacaa gctctaccag tatccagtcg ctgctattaa ggaccttcgt gcttctgaag
     6061 aagccttctc aaaccgttcc caaaccaaga acacttacga acttgaactc aacttggaag
     6121 ctaatagcca gagcgagatt gtcttacttg ctgataaaga aggtaaggga ctttcaatca
     6181 actttgacct tgtaaacggt caagtgacag tggatcgtag ccaggctgga gaacagtatg
     6241 cccaagaatt tgggacaact cgttcttgcc ctatcgagaa tcaggctact actgctacaa
     6301 tcttcatcga taactctgtc tttgaaattt tcatcaataa aggagaaaaa gtattttctg
     6361 gtcgtgtctt cccacatgcg gaccaaaatg gtatcctgat caaatctgga aacccaactg
     6421 gaacttacta tgaattagat tatggtcgca aaactaactg atgtcgccaa acttgcaggc
     6481 gtcagtccta ctaccgtttc tcgggttatc aataaaaaag ggtatctatc tgagaaaacc
     6541 atccaaaaag tcaatgaagc catgagagaa ttaagctata aacccaacaa cctggctcgt
     6601 agtctgcaag gaaaatcagc taagttaatc ggcttgattt tccccaatat ttccaatgtt
     6661 ttctatgcag aattgattga taaattggaa caccaactct tcaaaaatgg ttacaagacc
     6721 atcatctgca acagtgaaca tgattctgag aaggaacgtg aatacatcga aatgttggaa
     6781 gccaatcagg tggacggcat catttctggt agtcacaacc taggaatcga agactacaat
     6841 cgtgtgacag cgccgattat ttcctttgac cgaaacctat cgccagacat ccctgtcgtc
     6901 tcctctgaca actatgctgg tggggttctt gctgcccaaa ccttggtcaa gacaggtgcc
     6961 cagtctatca tcatgattac agggaatgac aattctaatt cgccaaccgg actgcgccac
     7021 gctggttttg catccgtact cccaaaagct cctattatca atgtttccag tgacttttct
     7081 cccgtcagaa aagaaatgga aatcaagaat atcttgaccc gggaaaaacc agatgccatt
     7141 tttgcttcgg atgatttgac agctattctg gtcattaaaa tcgctcaaga attgggcatt
     7201 tctgtcccaa aagagctcaa ggtcatcggc tatgatggga cctactttat cgaaaattac
     7261 taccctcaat tggctactat caagcaacct ttggaagaga ttgcttgtct cactattgat
     7321 cttctcttgc aaaagattga aggcaaggaa gtcgccacaa ctggttactt cttaccagtt
     7381 acgctattac caggaaaaag tatttaaaca caagaaaact cagaccgatt cgtctgagtt
     7441 tttatgatct taaattttcg agatagcgct gggctgtctc taggttaaag gttttatctg
     7501 cgataagctg ctcgactagg ggagcaactt cagattcact agccccagct aggagagcta
     7561 gggatttggc ctgtagtttc atgtggcctt gctggatgcc cgtacttacc aaggctttga
     7621 gggctgcaaa attttgagca agaccgatgg acacgataat ctgggctaat tctctggcag
     7681 aaggatttcc tagtagatca tgactgagaa ctacacgtgg gttgaggccg atagagccac
     7741 ccttagtcgc tacaggcatg ggcagggtca tctcaccgac caattcttct ctttcaaggt
     7801 ccagcgtcca gcaactaaga ccttgataac gtccatctcg actggcaaag gcatgggccc
     7861 cagcttcgat ggcacgccag tcattaccag tggcaatcaa aatcgcatca ataccattaa
     7921 aaattccttt attatgagta gcagctcggt aaggatcagc ctgcgcaaac tgactagcca
     7981 acgcaatttt ctccgcaatc tctcgtcctt gatccttttg gcggctcaag tagcgaaagg
     8041 cgatgcgaca gcttgcagtc accagagaat cggtcgcgta gttggacagg attgccatga
     8101 gactctgtcc ctgactgagt tcttctaaga ctggtttcaa ggcttccagc atggtgttga
     8161 gcatattggc acccatggct tcctgggtat cgacatgaat ataaacaacg agaaagtctg
     8221 gttcaccttt tatctgctcg acatgcagat cacgcgcccc acctccacgt ttaacgatag
     8281 aaggataggc ttgattggca agctccaaga gctccgcttt cttgctggca atcttctctt
     8341 gcgctagttt aggattagca acttgataaa gggctacctg cccaatcatc tgtcgctgat
     8401 ggacttgtgc agtaaaacca cctgcacgct tgatgatttt gctggcatag ctggccgccg
     8461 caaccacaga gggttcttct gtcacatagg gaacggtgta ttcctgaccg ttgacaagta
     8521 cctccggaac cagtgaataa ggcagagaaa aagttcccac tacattctca ctcagctggt
     8581 ctgccacagt cacgctcatc tgttcatcct tctccagact agcttgtctc tcaggactaa
     8641 ggagcgcctg agcttttaac agctcgaggc gctcttggta tgatttttta gaaaatccat
     8701 tccaacttat cttcattatt tttcaacctt gctataacgg cgttggtggt cgagaatttc
     8761 aaccaaggca aaatcttgat tttcatagcc agcaaactgg gcagagtttg tttcatccaa
     8821 gtttacttcc tcaaaaaaga ccttttcata gtctgcaacg gatagggcag ttcgttggtt
     8881 gagcttgttc aagcggtctt tatccaaata agcttcatat ccttcaacca attcaccact
     8941 gaagaactca gccacagctc cacttccgta actataaagg gcgattttat ccccagcttt
     9001 caagctatct gtattttcca agagagacaa aagtccaagg aaaagtgaac ctgtgtagat
     9061 attccccacc ttttgactgt agagaataga ctggtcaaaa tgcttttgta agaggtcttt
     9121 tttctcttga ggcaggctct tatccatgat ttttttcaag ccttttagcg ctaatttagg
     9181 ataaggcaag tggaaacaaa cagccgcaaa atcatccaaa gtaagctggt agcgtttttg
     9241 atattcaagc caagtcgttt tcaaactatc caagtattgt tgggtagaat agacaccatt
     9301 tacataagga gttgtcgagt aatttggtcg ccagaaatcc atgatgtcac gggtctgagc
     9361 tacattgtca ttattaaagg ccatcatgcg tggattttgt gtaatcaaca tagctacact
     9421 tccagcacct tgagttggtt ctcctggagt ttcaataccg tatttggcaa tatcactggc
     9481 aatgaccaag accttggact ccggagaatt ttccacatgc aatttggcat aatggagggc
     9541 agcagtcgct ccgtagcagg cttctttaat ctcgaaacta cgagcaaagg gctggatgcc
     9601 cagcaagcca tgcacaaaga cggccgcagc cttactctgg tcaattcctg actcggtcgc
     9661 cacaatgacc atgtcaactt cttgtctttc ttgctcagtt aaaatagagt cactagcact
     9721 ggccgccaag gtcacgatat cctcagttag gggcgcaata ctcaattcct tgagtaagag
     9781 tcctttactt aatttttcag ggtcaattcc cctcgcttct gctaagtctt gtaatttcaa
     9841 gacatattga ctggtcgcaa aaccaatctt atcaataccg attgtcatat ttacctctgt
     9901 tttatcattc atgtaaaaaa tcgttctata ctattttatc acaaatggca gtaaaagaga
     9961 gaaaaaagac ttgattcacc aaatcaagcc tcttattggt catcatttta aagaatgatt
    10021 agttgctaga gagttcaccg atataagtag ctttataagc tccattcaca gttatcagct
    10081 cctggaggat caaatttcct gagtaagtcc ttcccatctc atctacaaat ttttgataaa
    10141 actgactggt cggaatttct ctgacatcct tatcaaatgt cttatcaagt gttttactaa
    10201 ccttctcagc aatcaattga tgctcttgcc atccactttg aaactctgag cccgaactag
    10261 aaaccatgac tgggataaac aacaaggtca gtagacttac agacaataag gaaaatagta
    10321 gacttcctgc aaaactagaa tcctagttca tgattgataa taccagcaat caaattcatt
    10381 cgtaatccga agcgtttacg atgatttcga taggttgttg aaaacatttt aaacgttttt
    10441 actttggcaa agatgttctc aaccttgctt ctctccttag atagcgcatg gttataagct
    10501 ttatcttcag ctattaacgg cttgaggttg ctggatttac gtggagtttg tgcttgagga
    10561 tatatcttca tgggcccttg ataaccactg tcagccaaga ttttaccagc ttgtccgata
    10621 tttctgcgac tcattttgaa caacttcata tcatggcaat agaaacaatt ctcccttgac
    10681 ttgtgacaat cgcttgagcc ttcatagcgt ggcatttttt ttaccagaat cattcgctaa
    10741 ttgttttttt agggcgattg atttttactt ccgtcgcatc aatcattacc gtgtcctcag
    10801 aactgagagg agttcttgaa atcgtaacac cactttgaac aagagttact tcaacccatt
    10861 ggctccgacg gagtaagttg ctttcgtgaa caccaaaatc agccgcaatt tcttcataag
    10921 tgcggtattc tcacacatat agaaagcgtt gttaatttat ttatctcatt tttcagaaaa
    10981 ttcttttatt tctgtaaagt ctacgatact cgatgtgttt ttatataatg atacagtctg
    11041 agaatcactg ttccgctagc cattccaata gagattacca gagccaacat gacaaccaag
    11101 gtcgcacttg ccagtgcttt attatagtcc cctgtcacaa aaaaggcagt tgttcggtag
    11161 gagagataac ctggaaccag cggtgccaaa atggccaaga taaagaccac agcaggtgtc
    11221 ttataaagaa tacttaaaat ctggctgaca caagaaccaa taatggctgc aatgaaggta
    11281 gctacaatga cattggtcgg ttccttgagc aagagataga ttagccagac agtcatgccc
    11341 aaaatccctc caggtaagag catagaccgt tgcacattga gtacgattaa aaaagtgata
    11401 atggcaagaa aacttgctac tgcttgtaat aaaaaggttg ttagtgtcat attagttcat
    11461 caataccaag gcgacagaag ttcctgcccc taaagcgagg gtaatgagca gggattcaaa
    11521 catcttactc ataccagagt ttatgtggtt ggtcataata tcacggaccg cattggtcaa
    11581 ggcaatacct ggtacaaacg gcatgaccgc accagctata atcaaatctg ccgttgaagg
    11641 aaaacctgtg tagcgagccc aaaactgggc aattatccca aagacaaagg ctccagcaaa
    11701 ggctgtcaca aagggaattc ggataaattt ttccacatag agggaaaagg caaaaccaaa
    11761 taaggtcgcc actcctgccc caagtgcgtc gtagatattt ccgctaaaca taactgaaaa
    11821 gaaaggagca ctaaaggtcg cagccagagt tacctgcaac ttagtatagg gaaggggttg
    11881 agcttgcaag gccgtcaatt gcttaaaggc tgtttctaag tcaatctgcc ccccaactag
    11941 ctgacgagaa atctggttca catcgcagac tttttcgatg ttataagaag aggaggtcac
    12001 gcgcttcatg cgcgaaatat tggtattttc aatagagaaa aagatagcgg caggcatggc
    12061 aaggacattg caatccacaa tcccctgcga atgcgcgatt cgaatcatgg tatcttctac
    12121 acgatggatt tctgagccac ttttaaggag aatagtcccc gctagcataa tcacatcaat
    12181 gacggcattt aattcttttg attcttccat gctttcctcc ttttatcaac tccctctatt
    12241 ctatcacaaa tctggactca aaaaaaatct ttgccatgaa atcatgacaa agattgatta
    12301 ctcattttga ttatccatct acttttaagg agtagctgaa gttgttttag gtttgtagat
    12361 tgaaatcttg actctagtct tattgaggtc taccttttca cctgctctag gactttgttc
    12421 aacaaccatg ccttctgcac tacctgcagg cgctgtcgtc acttctacaa cttctatatt
    12481 agcttcctta atcccaacaa tttgaatcaa attgttctta gtaaactcca agctggaacc
    12541 aatgtaactc ggcatggcaa cacttgtaac ttttttagct actgtcaaga caatttgagt
    12601 aggtttactc acatcataag tcgttccggc acctggactt tgtttcataa tcgttcctgg
    12661 ttcgctttcg ctggactctt cttcctctat cttaatcaaa ttctcaggaa ccttcttctg
    12721 cttgagttct gagattactt ctgtagagtt ccgtccaata tagttcccta attgaatcgt
    12781 cgtagctttt ttagctactg tcaaaacaat ttgagttgcc ttgctcaagt cataggtcgt
    12841 accttctggt agactttgct tcaggaccgt tccagcctca ctctcattcg actcttcttc
    12901 ctcaatttta atcaaattat ctggaacttt tttctctttt aattccgcga taacatcaga
    12961 agatttccgg ccgacataat tactaatttg gaaggattgt ttgcctgatg agacaaccag
    13021 attgattttc gttccttctt ttcgaccagt tccagcgcca ggatctgtac ggataatccg
    13081 cccttcttcc accttttcac tagcctctgt cttctcctca ccaatctcaa aattggcttt
    13141 tttgagcgtt gccttggcct ctgcaactgt ctgacctgcc acatctggaa tggcaatggt
    13201 tgcaggagtt ctggatagta tccaaataag agaagctgcc accaatacaa ggctggccaa
    13261 caaaatcagg taacgcatct taaatctatg ttttttcggt gcttgtggtt ggtaagtttc
    13321 ctctgtcaca gcctggcttg ggtttttgat tgatttgtgt tctgtctgcg cttgaacctt
    13381 aggaatagat gtcaaggtac tctgagaaac cttcggcaag gtcttggtat ctgccttgct
    13441 cgtttcatca aagattaact tactttcatt tctacgattg taggacaagc tactagacaa
    13501 gtccacatac atctctgaaa ccgagcggta gcgattggtc aactttttag cagttgcctt
    13561 gataataaca ttttctaaag cctgaggtac agatggattt tctgcaataa cggacggcag
    13621 gggtttctgg aaatgctgga gggcaatggt caccgcgcta tccccgtcat aagggatatg
    13681 gcctgtcaac atctcataga aaataatccc catggcatag atatcactct gcacagtcgc
    13741 cttcgaacca cgcgcctgct ctggtgacaa gtaatgaact gagcccaaca tcgagttagt
    13801 ctgggtcaga cttgtctctg caaaggctac agcaatccca aagtctgtga ccttggccgt
    13861 cccatctggt gtcaaaagga tattttgagg tttcaagtcc ctgtgaacaa ttcctcgagt
    13921 atgggccaag cgcatagcca agagaatttg tcccatgata cggactgctt cttcattaga
    13981 aagaggataa tgttccttga tatagcgttt gaggtctagt ccagcaacat actccattgc
    14041 aagatactgt tgaccgtctt cctcaccaat atctgttatc cgaacgatat gaggatggtc
    14101 tagatctgcc atagctctcg cttcacgctg aaaacgagct acagctatcg ggtccgtctg
    14161 gtagttggtc ctcagaacct tcactgccac ttcttcccca tctaagatta agtctttggc
    14221 taggtagaca tccgccatac ctcctcgacc aatctgtttg acaatccgat agcgtccggc
    14281 aaaaatcttg ccgatttgga tcattctgca tcctcctcgt tcatagaaac aagggcaacc
    14341 gtaatgttgt ctaaacctcc tgcattgtta gcaaaacgaa caagtgtctc cgttttatct
    14401 gctaaaggaa tatcactggt tacaatatca cgaatctcac tgcctgaaat catgttggtc
    14461 aagccgtcac tattgagcaa gagatagtca cctgactcaa ggataactgt cccaaaatca
    14521 ggctgaattt catctttttg cccaatagac tgggtgataa tatttttttg cggatgagct
    14581 tctgcctctt ctggtgtcaa ttgaccagcc ttgagcaatt cattaaccaa ggaatgatcg
    14641 ctcgtcaact gatggtattc ttctccacga atcaagccga tacgcgaatc accaatatga
    14701 gcatagatag cctgattatc aataatagca aggacttcca aagtagttcc catgcctctg
    14761 taagcttcat cctgaccaag ctggtgaatc ttttgatttt caatttctag gtaatgggcg
    14821 aaccattcac gcacttcatt gactgtatcg atctgggtat caacccaagc tacacccagg
    14881 tctgtgaccg ccatttcact agcgatattc cctgcacgat gacctcccat cccatcagct
    14941 aaaataatca tggtacgtcc agctctattg acatagtggt tgacatagtc ttggttattt
    15001 gttcgtttct gaccaacatc tgttaataat gaaatttcca tgtgtcagtt ccttcctaat
    15061 ccgatatctt gcgaaattga ctgatgaaga atccatcact tccatacaat tcaggtgtaa
    15121 tgaggataca gccgtctttc atgatatcct tacattcatg ttctagtttt acctgctcga
    15181 actcgggatg actctctaaa aaggccttaa cgacttgaaa attctcctct gagacgatag
    15241 tgcaggtgct ataagttatt ataccacctt tgcctagtat ttgacaaaca ctacctaata
    15301 tttctaactg aatttcctgc aaggacgcga aatctgccgt ttctttattg tatttgatat
    15361 ctggttttcg gcgcaaaaga ccgattcctg aacaaggagc atccaccaaa atcttatcaa
    15421 aggaatcctg gtcaaaaaac tcatgcacct ttctggcatc caatttttga gtttgaaccc
    15481 gatcttcaac tcccagacgt tgggcatttt cttgaattaa atccaacttg tggtcgtaca
    15541 agtccagagc agtaacctga cctgtcgtaa gataagaggc tatatgggct gttttcccac
    15601 ctggagccgc acaggcatca agcactcgct catcaccttg taaatcaagc gtcggagcaa
    15661 ccagctgact ggactcatct tggatggtaa tggctccatc cgcaaacaaa ttatgccctg
    15721 caaaatgccc ttgctcctta accagaccag tggttgctaa aagggaacta ttcgcctcca
    15781 acaaggcttg gatttcctct tttcgactta ggtctgttac acgaatacta gctttgtttc
    15841 gcactaacaa gctttcaaag atggcttttg ctctctcctc tccgtattct tccttgagtt
    15901 tggtaactag ccaaactggg agagaatagg caatggagtc acgcttgttt tttcgcttga
    15961 tgttagcaat atctggccag ccttcacgca agatacggcg aaggacagcg ttgaccaatt
    16021 tttcactgcc ttttttacgg agtttggcca attccactgc ttcattgacc acagcatgat
    16081 ctggaatctt gtccaaatag cggagttggt agacactcat gagaagaagg acatagagcc
    16141 agctgtctaa ctggtctctg tcttcgataa agtgggatag gtaccattcc agagtcagtt
    16201 tacgggctac cgttccatag actagctcgg tcactaagcc cttgtctgct gcagagagct
    16261 gactcccctt gaggtgttta tttaaggcga tatttgaata tgcttggttc acaaaaacat
    16321 cctctagcac tgctagagct aaacttctag ccgtttctac tttagtcacc aaatcgttct
    16381 cctacagtca atgtacgtcc aactccgttg aggaaggaag caatgtccat cttaggctta
    16441 ccagctggct gcacttgttt gagggataga gccccttcag ccgttgcgac aatcaattct
    16501 ttcttgccga tagagagaat ctcacctgga tttccctgac cttctactgg tagggcttca
    16561 taaatcttaa agcggtcgcc cttaaggaaa gtatgggcaa caggccaggg gttcattcca
    16621 cgaatttggt taaagagttg acgattggtt ttgttccagt ccagtttttc ttcctctggc
    16681 tttatatttg gagagaaggt aacctgactc gtatcctgcg gttcaggttt gatatcacca
    16741 gcaatatagg caggcagagt gtccaaaagc aaatcacgac caactagcgc caatttttca
    16801 aacaaggtgc caacattgtc ctcatctgtg atcggaatgc tgcgacgaga aatcatatct
    16861 cctgcatcca tttccttaac catttccatg atggtcacac cagcttcctc atccccttga
    16921 atcaaggcat aatggatagg cgcaccacca cggtgtctag gaaggaggga ggcatgaacg
    16981 ttgacagcaa agtccatgct atcaaggagt ttgcttggga gaaactgccc aaaagcagca
    17041 gtcacaattc catctgctcc tagcttcata agttcttcca tctctggact tccagataat
    17101 ttttcaggtt ggtagataga tagtcctgct tccttggcag cctgcttgac tggggtttct
    17161 tggataactt ttttacgacc aacagcacgg tctggctggg tcacaacggc tagaatttcg
    17221 taacggtcat ctgtcaaaag tccttttaag actgttgctg aaaagtcggg ggtccccata
    17281 aagattagtt ttgtcatatc ttctccttct tataaaaatt gctgcggctc atggtcaatg
    17341 ctgagacgga gctcactatt ttcccgttct tgagtcaagg ccaagacctg gttgagggtc
    17401 ggccccagct catcttctaa acggtattta attaaaatct ggtaatgata gaggttgtgg
    17461 gtacgggcaa tcggttttgg cgttggcccc agaatgggac tggtctctga caagcctgac
    17521 cgcaaaatgt tcatgacttc ataggcacgt ttgaaaacct cttcttcttt cttgtgagaa
    17581 agggtaatac caatcgtgaa atagtaaggt ggatagccga gttgtcgtct gattcccatt
    17641 tcataggcat aaaagccttc gtaatcttga tccttggcaa atcgaatagc atagtgctgc
    17701 gaattgtagg actgtatcaa gacttgacct gctttttcag cccgacctgc tcgacctgct
    17761 acctgagtca agagctggaa ggttctctca gaagaacgga aatcaggcag attcaaggcc
    17821 gtatccgcat ttagaactcc gactagggta acattgggaa aatccaaacc ctttgcaatc
    17881 atctgagtac caagtaaaat atccgcttcc cctcgcccaa actggtcaag caaggcttgg
    17941 tgactgcctt tctttcgagt cgtatccaca tccatcctaa aaatgcgagc ttggggaaag
    18001 agttctgcta gctcatcata agccttctga gttcccgtcc catagtaacg aatactgtgg
    18061 ctcttacagt taggacagac ctgaggaata tccttcgaga aaccacaata atggcagttc
    18121 atagtcttgg tatccatatg caaggtcaga gaaatatcgc agttgggaca agtatccacc
    18181 gtcccacact cccgacacat gacaaagcta gaataaccac ggcgattgag catgagaacc
    18241 acctgctctt ttttaaccag acggtcttgg atagcctcta gcaaaggagg cgtaaagttt
    18301 gacgtctcat tttgtccgat atagtctcga aagtcaatca cttgaacctc agggattgta
    18361 gccaaaggat tggcacgttg ggttagacgt aagtgttgat agacgccttt gccagcacgt
    18421 gcccggctct ctaagctcgg cgttgcagat ccaagtacca gagttgcttg attatactga
    18481 gcccgtaaaa tagctacctc tctggcatgg taacggggat tgctgtcctg cttataagcc
    18541 gcttcatgct cttcatcaat aatcatgaca cccagatttt tcagaggagc aaagatagca
    18601 gatctggcac caacaacaac ttgggcatcg ccacgctcca ccttgcgcca ttcatcatac
    18661 ttttcaccat tggataatcc tgagtgaaga atggctacct tgtccccaaa acgtgctata
    18721 aaacgctcgg tcatctgagg agtcaaggaa atctcaggta ccagcaaaat agctgtcttg
    18781 cccttatcca gggcaccttg gataatctgc aagtaaacct cggtcttccc acttcctgta
    18841 atcccttgaa gtagaaaggg aggttgagaa ctgccaatag aactcacaac cgcatcacgc
    18901 gcctgtcttt gttctggatt taactccaaa ggtctacttg cttcaattcc ttcaaaataa
    18961 gcagccgagc gttgaacttc cttttggact atggtaacag caccttgatc cacaaagaag
    19021 ttgacttgct ctcgcgagta ggactctaac aagctagcca aggaagcgct ctctggatga
    19081 gacagcagat aatctctcag ttccaacttt ttcttggcac gtgtagaaat ctcaacacct
    19141 tctaattggg catggtcaac ctcataccaa gactgggtct tgaccttctt ttgatcgact
    19201 gcctgatatt ccagaccaag caggcctttt ctagtcaaac gcatcatttc agcttgcttg
    19261 gcaaggtcta gtgaagaaaa ggctagcgaa tcttctgaac caaacaggcg tactcgttct
    19321 tcctgactca agccttccag aggatagaga atcttgtcat agctagaatt cagaaatcct
    19381 ggaagcatgg tcttgaggat agagattttg taggagaaga cagatttgcg taactcctca
    19441 gccagccaga gttgttctgg cgtgagaaca ggagaaaaat ccagcacctc tgcaatatct
    19501 tttaaatctt gctccatctc ttctccatct gattgggact ccaaaccaag aacaatccct
    19561 tgaatcaggc gattaccctt accaaaaggt acatgaaccc gcatcccaac ttccagcatt
    19621 ccctcaaatt cctccggaat cctgtaacta tagggctggt ccgtctgcat caaaggcaca
    19681 tctacgataa tcttagctag ggccatcttc tcacctcctc cttgtcagta cattcttgca
    19741 atagaaaaaa taagattgag tccccccaac cttaaatttt ttcaccatct tctttttctt
    19801 tagcaatttg ctctttgatt ttcttttctt cttcttcttt gcggcgtttc tcttcttcga
    19861 tacggcgacg cactgcttca cgttttcctt ctggatctgg gtgaattgta acgtttcctg
    19921 attcgatttc ttctaaagcg cgaagagttg atttttcaga cttgaaacct tgagttgctg
    19981 gggcacctgc ttccaattcg tgggcacgtt ttgcttccaa gattacgagt gaatattttg
    20041 aaggaacctt gtcgagcaag gtatcaatag agggttttaa catcatttgc ttgtacctat
    20101 tttctaaatt ttatcgggta gttggagatt ttggtaacat ctcctgatag tgaccaatga
    20161 cacgatccac acagaagtgt tctgcttcaa tcacacattt gacacgttca gcagctaggg
    20221 gcacctgatc gttgacaatc gcataatcat actcacgcat gagggcaatt tcttccttgg
    20281 ccttttcgat tcgttgggca atcacttctg cactatctgt tccacgacct accaagcgat
    20341 cttgcaattc atccaaatct ggtggtgtca ggaagataaa gacagcatct ggaacctttt
    20401 tcttgacctg aagagcaccc tgaacttcaa tttcaaggaa aacatcgatt cccttgtcca
    20461 aggtttcatt gacataggtc agaggagttc catagtagtt gccgacatat tctgcgtatt
    20521 ccaacatctg tccttgacga atcagctctt caaattcttc acgagtacgg aagaaatagt
    20581 caacaccgtc cacttctcca ggacgttgtg cgcgtgtcgt catcgataca gaatattgaa
    20641 attggttttc agaactctca aaaatctctc ttctaaccgt tccttttcca acccctgaag
    20701 gaccagaaaa aacgattagt aagcctcggt ctgccattgt gtctcctttt agtcaatctg
    20761 tgaaataaca tttctctaga ataatggcaa aaagccagat tatcctttac agtctttcta
    20821 tctagtgtaa caaaaaagca gtaatttttc aactgctctt tcttatttat ttagcataat
    20881 ctactgcacg aagctcgcga atcacggtta ccttgatatt tcctggataa tcgagattgt
    20941 tttcaatttt cttacgaact ttgtgagcca agattgtgac tttgtcgtcc ttgatttttc
    21001 ctggattgac catgatacga atttcacgtc ctgcttgaag ggcaaagcta gtttgcactc
    21061 cttcaaagcc gttagcaatt tcttccaaat catggagacg cttgatgtag ctttcaagag
    21121 actcactacg agcacctgga cgggctgcgc tcaaggcatc tgctgcagcg acgataactg
    21181 ctatcacgct ctcagcttca acatctccgt ggtgactagc aatcgtattc accacaactg
    21241 ggggttcctt gtacttacgg gccaattcca taccgatttc aacgtggcta ccttcaacct
    21301 catggtcaat ggctttcccg atatcgtgaa ggaatccagc acgacgggca agagccgcat
    21361 tttcaccaag ttcgctcgcc atgataccag ccaacttagc aacctcaatc gaatggcgca
    21421 aaacattttg tccatatgaa gtacggaact gcaaacgtcc cataatcttc atcaagtctg
    21481 gatgaaggtt tggcgcacca atttcatagg cagcagcctc accgtattca cgaatcttat
    21541 tgtcaatctc ttgacggttt ttctcaacca actcttcgat acgagctgga tgtatacgac
    21601 catctttgag caacatttcc atagtcatac gggcaatctc acgacgaatc ggatcaaatc
    21661 ctgacaaggt caccacttct ggtgtatcgt cgataatcac atcgacccct gtcaaacttt
    21721 caaaggtacg aatgttacga ccttcacgac caataatgcg tcccttcata gtatcgtctg
    21781 gcagatgaac tgttgagttt gttgactccg ctacatattc accagcgata cgttgcatag
    21841 cttgaaccaa gatatccttg gccattttgt cagaacgttc cttgacctct tgctcagctt
    21901 cgcgaatgcg actggcaatc tccctggtca agttttcctc tgtctgagcc aagataatat
    21961 ctcgtgcttc tgcctgagac agagcaccaa tacgctctag ttctgcttct ttttgtcttt
    22021 cgacttcctc taattgctct tcacgcgcat caaggttttt cgctctatca gaaatacttt
    22081 gttctttttg ttcaagtgtt tgttctttac tcgtcaaatt gtcgtcctta cggtcaaggc
    22141 tagtagctct ctctgtcaaa cgactttcga tttgtttgag ttcttgacgt tctgatttga
    22201 attcagcgtc cacttcttca cggtattttc tggcttcttc tttggcctcc aatagtgctt
    22261 cttttttaag agacttgctt tcacgtttag cttcattaac aagtaaatcc gcttcacgct
    22321 cagcttgtcc acgtaaatta gttgcttctt gttcagcatt taaaagcatc aactccgcag
    22381 cttcctgaga tgatttcatc ttagctgaga tgctgacata tccaatgact aaaccaatga
    22441 tgacggcaaa aacagcaatc gcaagcgaca tgatctccat gtttttacct cattttattg
    22501 ttattccgaa tgacatacat tcttttacat tctaccataa aaaagtgatt ttcacaaacc
    22561 taaaatagaa tatgttttgg ggaaattagt ctgaatttta ggattacact tccttggttt
    22621 tttaaggaga taagtcagtg ccgctatcaa aaagttccac cgaatttcta ccgctatgga
    22681 ttttctattg ttgtgccaaa tagtgttcca ctagattcaa acattttgct ttcaagtctt
    22741 tgaaaattca ctttaggaaa tcacagctta tcttcaagat caaatttgtc ataaattaac
    22801 ttttttattt agttgtatca atttatttct taagtattaa tttatcctca tcgaaagctt
    22861 ttaaaatata ctcattaatc aatttattat cttcttcatt ttttgaaaaa taagttttaa
    22921 tattattggg agttctatgt tctagtagac gatggataac atcatcactt ctatcatgga
    22981 accaggtcca atctacttca ggataaagtc ctcgaatatc ttcttcaata tcttttaaaa
    23041 tctcaaaatc agaaaaatat ccttttctac ttaagttgta taaatctgat acagactttt
    23101 ctcttgggtc tgggaaagtt ttaaccccct caactctttt atcattaatt cttttaatca
    23161 aataatggta gattttattt tgtatctgag gaaaatcata gacattataa ctcatcaaat
    23221 caattacttt atggtaaata atattttctg attcttcata aacttttaga gtatctaaaa
    23281 tgtcatcttt aatatccttt tcaaaatact taaataagtg acatatcaag tcagaatatt
    23341 ctatgatatt ttttatatca tcatttttat attttattct taaaatatct gtattaaatt
    23401 tttcgagtac tattattgca gtttcctgat cagttgagca gtattctagt aactgtgaat
    23461 agagcggata cactgaatta tataaagaaa aatttttctc caaaatttca tttaaatgtt
    23521 tatttacaat cccaattatc ttagatttca atgaatcttt atcaataaca tccatattat
    23581 cgaggacaat tttaataatt ctcctaaatt cctcgctcca attataatac agtgtttgat
    23641 tatttaaaat ttctattact ttttctatgt caatatcatc aacaagggga agaaaaatta
    23701 gcatattttt aagctctcga agattttcat cttcagtaat ttcaagtctt tcttgaagat
    23761 aagtaattcg attcaacaag tagtctttcg cttcctcagt aacttttatt ttaccaaatg
    23821 aatagtttct aaaatataaa tttacaacct taaaatctat attcggaaga attaatttaa
    23881 catcatccaa atcaagattt ttaagccaag aagatgttct atcgaaaata cttgagtcag
    23941 ggtttacata tgaattatca taactgagta ataatatttc taaatatcta ttaatgattg
    24001 atttataaat cttataatgt tcaacacata aacaatttaa ttttaaaaag ttataaagat
    24061 tttttactgt aaactccgca ttaaatagat gattattagc agaccatcct cctcttctat
    24121 agctttcatg ctcttcacga atttcatcaa ataattcatt aatagtttct aattttctat
    24181 ataaaaaatt gaagttaagg attgaatctc taaaaaattc tataatcttt ttctcatctc
    24241 ctgtaaccga gttaagaatt tgttctgtta attcgcttaa ttctccatca taaagtggct
    24301 ctgcataact aggtgttttt tcgtatctat caattatttg aatttgctga aaattaaatt
    24361 cacaaactaa gaaattaaaa tagtctttct gacgaaatgc tatattagct agttctctaa
    24421 attttgcttt tgctaaagaa tattgttttt cttcatacaa cttaaaagcc ttacttaaga
    24481 atcgattccc ctttaaatcc ctaggctcac caatctccat atctagaaag cgatttaata
    24541 aagatttttt agataccata attcgtaatt cttcatgacc atcaatttca aatcttaatt
    24601 gatcatttcc aaaccagcaa tactcatcat cccagtttaa agcccttttc tttaaatcag
    24661 aatatctaga aaaatctttc gcatcaataa aactaagtct atctaaaaaa gccagttgat
    24721 tccataaatc atcagcatta tttacatctt gacttcggtt ttctgataga acctctaaaa
    24781 aatcttttgt cctgcaatac aatttgttct gtttttctga tgtctcctga cctagattct
    24841 cttcattaga gataatgaaa attccttgct tcttataata ctctcgaatg atcatagacg
    24901 gttcctcggg agtataaaaa taagcatttt tagcatccaa tttaaatgta ttttgaatca
    24961 ttctaaaaat tgaattaaaa gtcgaatcac ttagagaata ccccacaaac aatagagtat
    25021 gattcattat caatgactgg attaaagtag aaatcattgg gaagttcaaa tgatagtcta
    25081 aataatcatc ttctttcaaa acaatatttt tcttactgaa gtcaccatgc attttaatca
    25141 agtatctttc cgaactcgta taagggatgt ctttatcctc agcgactaca ttgtacttta
    25201 acaagccact ttcaaattga ctctccagaa gtgaatcata gtttgtcgta ataatatgtt
    25261 ttggtgcaat tttttctatt aatttatgta actcatttgg tttactcaat cccttcttaa
    25321 agaaaatttc ttctatcttc tttgtgtact gatttttccc aaaagtatca taataatact
    25381 gagcaattct cagtggacta tctgttcttt cttctggtat gttcaattct ttttttaatg
    25441 attgaatcaa ttctccccaa gttggtagat tagaattagc tgatattcct gcaccaacaa
    25501 acaaaactaa ggaattttct ttaatagaat tctttatttg agttatagat aaattataat
    25561 tttcttccat attttaacta tcctacatta gcttgtacta cataaataca aattatcctt
    25621 ataaatcttc ttttttatta cataatctta aacaaaagtt tatcatggtt tataaatata
    25681 aaaatttatt tgtcttttat attcaattta tgattattaa tataaccagt tctcttcatt
    25741 ataccacaaa ataacaagca taaagcggat tcaaagataa agattaaggt tcatatacta
    25801 attttcttta ttgacttttt gtcttctgta ttagggagtt tatcattttc caaaaacttt
    25861 atcttcaatt tgttatctaa aatttctaca ataaaaaagc ctacctttca gtagacttag
    25921 tttgtttcta ttctaatcgg cactctgcca aaattttgct ctgctatact tggctttcct
    25981 agttggtaaa tctggtcaac cttttgagtc atagcatccc aaggttcttt gccaattcgg
    26041 ctgactagat tgacctgtcc tttcagagac ttgagatgtt gcctgccttt ttcagtaaat
    26101 ccaaggacat gaatggcttc tggcaagaca ttttctctag cctgtaccaa aatataggtc
    26161 aataggcgtc tgacacgcgc cttggtgtaa cgtttggtag tcactaactc gaccaattct
    26221 tccacagact gggctgtttt aatagcttct ttaatgcgca cagccatttc ttgattgacc
    26281 tgatagatgg tggttaggtc gggatttgac aagatttgat agcggagcaa gggaaaatag
    26341 tcttcccaga tcaccttact ggcctgctca aatagggcaa cagaaggcat aaaacgttct
    26401 aagaaatctt ggtccttctg atgttgacgg agggctgtcg ccgaggcaaa gtccacatct
    26461 ttattcacag aatggtaacc tgccccctga cgctgaatcg gatgcagctt gatatttcgt
    26521 cctgcaaccg cctttgcata ggccagagca agaacatgat tgggggtatt acctgaaaaa
    26581 tcaagaccag caaattcctt ccacatagct tgggttttct ggggatagga aagggaatca
    26641 ggcagatttt tcacaaattt ctccatctca gcacctttct ctgtgtataa gtcagcgatt
    26701 ttctggtaat ccagaacttc ctctgtccca aaaactagac tatcaatgcc caagcgatcc
    26761 aagatatcca cagctccttg accaaagaaa tcagctgcct gaacactgac taaaaagggc
    26821 aattccacta ccaagtctgc gccattttcc agcgccatct gggcccttgt ccacttatcc
    26881 acaatagcag gctctccacg ctgcatgaaa ttccctgaca tggcaacaat tttcagtccc
    26941 tctgcctgat ccagcaggta tttatggcca ttatgaaaag gattgaactc cgcgataata
    27001 cctgttatgg tcatgctaat ctcctacttc tgcgccacaa aaaaccaacg ggtgctagtt
    27061 tctgttggct ccttatcctc aaagtctgca tagagtttga aggacttgaa tccagcctgt
    27121 tccagcaaga tctcataggt caagatctca taggtcctct cctcatgtac ttcatcgtgg
    27181 cgactaaagg aaccatcagc ctccttgata aagaaagtca gctcatggac gatggagtga
    27241 ggaacttcgt cctcatatgt atcccaaagc atggcaaaat cttccgcatt ttcatggtag
    27301 gaatagccag ggaatacttc atctgtctgg taggtcgagt gcacgtcaaa gatgaaaact
    27361 ccctcttcat tcagcgcatt gtacacgtcc ttaaagacgt cccctacttc cacctcatcc
    27421 tgcatatagc agatagagtc cgaataacac gtgacaaaat cgtatttccc tgccttggac
    27481 aaattcagca tattaccttc tataaaagca atcttttgct tggctgaagt tgctctcttc
    27541 tccgcaatct tcaacatatc cgcactcaag tcaagtccag tcacatcaaa accagcctga
    27601 gagaagcgca ctgattgaat tcctgtccca caagccaatt ccaagagttt ctttctctcc
    27661 ttggtcttag gcaaatgacg cagagaaaaa ttcgtccatt tgtcgtataa actatcgtcc
    27721 atgaccgcat catagaccgc cgcaaaggtt tcataagtcg ccataatcat gatactaaga
    27781 gctccatggt aaacaccact agccctttac ctttctatca atttttctaa aataagcaaa
    27841 gaaacccagt tgactacaac tgagttcatc ttctaagcaa gagcttctga aatatctact
    27901 gaattcgcct catgccatag cttctctaga ttataatggg cacgcatttc ttctgaaaag
    27961 atatgcacga caacagcacc gaggtccagt aagacccagc ctccagctgc atcgccttcg
    28021 atatggctac ctttaaagcc tgcttgagct actttttcac ggatattagc tgcgatagcg
    28081 tccaactgac ggctattcat tgagctagtg atgacaaagt agtccgtcac actagtcaaa
    28141 tcttgtacat caagtgcgag gatatcctcc gcacgtttct catcagccgc tttcacgact
    28201 agttctagta attctttttc gttcatttaa tcctcttttt agaaaatatg tttgtaatct
    28261 agaacatctg caaagcactc ctcccaaatg tcctcataaa attcattaat cgtttctgct
    28321 ggaatgtcat ccccatcaaa ggttgtgaca gcaccttctg gaacaataag ctgatagcca
    28381 tattcaaagg caaccttgac agaggtatcc acacaatatt ctgtctgcat accacataaa
    28441 actaattttt caatcccctg tttatccaag tattctttta agccagtttc tttgaaaata
    28501 ctgttatact tcttctgaaa gaccttttca gcaggttttc gatttaaaag cgcagataac
    28561 tgccaatctt ctgatgtttg agcttcagaa ttctcaatat gttgaacata gataatttca
    28621 atattcttgc ttctagcctg gttttgtaaa taagaaattt tttccaatag actttttgtc
    28681 tggaacccag tttctactaa aacattctga acatcaatga ttataaaagc cgtcttcatt
    28741 tagtcctctt tcaaatagtg cacaaaggcg ttataggttt caagggtttg gggatagatg
    28801 gggaatccct gatgagctag atactccacg gtacgagctg tttcgtaggc caccgcctta
    28861 ttgagcgata gacttgcaat ctcacgcgcc acatctactc caggaaaggc tcgattgtgc
    28921 tcgatatagt ctgcgacgta gatgacctta tctaggtctg tcatttgacc agcaccgact
    28981 gtatggactt caatggctcg caggatttct gaatcatgca aatccaaatc ttcctgaatt
    29041 ttgtaaattc cgaccatacc atgccagaca ttattacccc agtttttgag gtcgaaatct
    29101 agctgataac ggtcaatcaa gtctagaaat tcctgatctg acaacttttt agcatagtca
    29161 tgaagaagac ctgctagact tgctttctca acatctacac caaagcgctg agctaactcc
    29221 atagcggcac gctccacacc tagacaatgg gttagacgtt tctcaggtag aagctctgcc
    29281 attttttcca acaaggcctc acgggagcag ttgatatagt cttgatagga catcagtaga
    29341 gcccctcctt ctcgatgtag tctagcactg gctgaggtag gagaaagttg ggtttccgac
    29401 cttgggcaat gaagtcccgc accatgctgg acgagatatc catgagcggt acgtccaccc
    29461 agataactgg ataggaagtc cctgccttgt agcgtggacg ctgaaccccc acaaactgaa
    29521 ccatgtcaac cagttcatca attcggtacc acttaggcag atagtcaacc atgtcggcac
    29581 cgatgataaa gtaataatcc gtatctggat gttgctctgt caagattttc atggtgtcgt
    29641 aggtgtagga aatacccttg cgctccaact caatggtttc aatgactagg ccgtcaatcc
    29701 cctcaattgc caactcaagc atcttgagac gatggtgttc agggatggtt tcctttttat
    29761 caacgtgagg aggttggtat tcaggcatga gaagaacttg atccagtccc aactgttgcc
    29821 gtacttgatc cgcaacaatg agatgggcat tgtgaacagg gttaaaattc ccccctaaaa
    29881 tcccaacttg tttgcgtttt ttctccttga tttctggctc caactctacc ttggtaaagg
    29941 gagtcaatag ttcgattgtc ataggctagt cccctttatt tctctataaa aacagttatt
    30001 tggagtttcg gtcttagatt tctttgactt tcttagaaat cttgcgattt tctttcttgc
    30061 tagattgttt aaacaaaatc aagatgcgtc ctattttttg gactgtatcc acaccgattt
    30121 cttcttccaa aatttcagct acttcgtgga tattttcatc tgtgttttgt aagagagtaa
    30181 ccttgattaa ttcacgcgca tcaagagctt gacggacgct ggttttgatt tggtcgttga
    30241 gtccattttt cccgatttgg atgataggtt tgagggtgtg tgcctggctg ttgaggaagg
    30301 cacgttgttt tgatgttaat gacataattt tcttccttgt ttttggatag ttattttagg
    30361 tggtgaggga cggtcggaac taattttcca aagatttcat ctttgaaaaa tggatttcct
    30421 gacctcacaa ttgagccttg gtctcaattg tgccccttgc caatctacag attggcaatc
    30481 acaccacggc aataactatc gctatatgag ctcactttgt tcgctcagcg attttgtttt
    30541 aaataattgc ttttcgtgtg acgacggcga cgccttctgg tgcccagacg gcgacttttg
    30601 ctatgcctgt tacacgaatc cagcctaggc ctgagatgac taggtctgtc ttatctttaa
    30661 tggtaaagac atgctggact agccttggga aatcttcttt ttccttgcta tttggtggtg
    30721 tcagaagagt tcccaggtgc ttatcgtaga aagcactagc tccttcaaac ttgctacgat
    30781 ggagtttgag ttcattatca aagaaagcag taaatccttg cttttctcct gctataaagt
    30841 caaagcgtcc caaaccacct aaaaataggg tttgctcagg attaagctga taggtcttag
    30901 gcttgatttc ctttttagga ctgacatact tgaggttttt ggccgtcaag tagtgagcca
    30961 tctggtggcg gtggataatt cccggcgtat cgtaaatata agatccgtcg tcaagcggaa
    31021 tctctatttt gtccaaggtt gtacctggga agcgtgaagt agtgatgaca ttctgatcac
    31081 ccgtgatttc ttggataata gcattgatta gagttgattt tccaacgttg gtcacaccga
    31141 ccacatagac atcgcggccc ttacggtagt gttcaatctt gtcaatgact tccttaatgg
    31201 catgtttatt ttgtgctgaa gttaggacca catcgactgg acgaagacct tcttcatggg
    31261 cacgtttcat gagccactgg ctaatcttac cagacttaac tgacttagga aggatatctt
    31321 ttttatttcc taccaagagg acatcattgc ccgagacgaa acgtggtaaa cctgggatga
    31381 cagatccatt aaaatcaaag atatcaatga cattgaccac taaggcatca ctgtctccca
    31441 cctcgtgcaa gagcttgagg aaatcatcgt tcgtcaactg gacatctgtg atttcattgt
    31501 agtggcggag acggaaacag cgttggcaat agacttcgcc agtctccaaa cctttttcaa
    31561 gtgccgactg gggggtaaaa ccaagaccag ctttatctgt cgtctgaatg gttgctccac
    31621 aaccaataca gagaatttct tccatagtta aattcctttt ttatatgtaa tcggtccgta
    31681 cttttcagtg atttttctca taacacgacg ctcacgagtt cggttaatct gcgttttgat
    31741 tgagtcatgt tggaccaagg gtttgactaa aattgaccga atccctgcac ggtgggctgc
    31801 tcgtatatct gtcatgagct ggtcgccaac catgaccact tcctttttgt catagtggaa
    31861 ttccttcata gcacggtcaa taccaaatgt gaagggcttc aaggcccagt aaacgtaatc
    31921 aatcccaaat ttctcaactg ctcgttgaac gcgttttttg gtgttatttg acactacgat
    31981 aatgccaata cccgcgtccc gaaggtcatg tagccattgc ttcatctctg gcgttccatc
    32041 agggttgttc caagcaatga gggtattatc caaatcgacc aaaacagcct tgattccctg
    32101 cgcctgcagg cttgggactg tcagatcata gactgcttcc acagcaaaat ctggtatata
    32161 attttcaatc gccattctgg ctccttttct taactttttt tcgcaatttt ccttagtaac
    32221 aaggataaaa caatccacaa acctgcacta gccaaactga tatagagcca agcatggggc
    32281 tcatctgtta aaggtaaggg aacattcatt ccgaaaaagc ctgtcacgac tgccaaaaca
    32341 gctagcaaga ctgaaatgat agtcaaggtt gtcaaattgt cattcagatt attgtttaga
    32401 atattgttgt aagaggctga aagctgctgt aaaatctgag agattaggtc tgtcatggat
    32461 accagctgat gagcctcaat catggcatca tcaaactgtt ctctctcaat ctcatcaaaa
    32521 ctacgataca aggcatgacc ttgaatatgc tctaacaaaa tccgattttg tttggcagct
    32581 gccgtcagat aaaccatacc agtctccaaa tcagacaggg caaagaggtt tttcttggta
    32641 gttcgctggc gcaagaggtc attgacctca tccctactct tgtccatctg ctcaatgaca
    32701 ggatagtagg cattgctgat aatttccaga ctggcaaaga gaaacttata aatcgaaagc
    32761 gtgtcatggc tctccagata acgagtcatc tgttcaatga cataggcgtt cttggtatta
    32821 ctaatggtaa tcaggcgacg atgctcgaca ataaaggtca tgggaaaagt ctcatagtag
    32881 gccttgtcct tttttacgtc taggacatta tagataaagg taaccgtccc actttcacgg
    32941 tggtaatcca tgtgggcgcg ctcgtttcta tccagtgcgt attcaatggt ttccttgtcc
    33001 aaaccgtaaa tttcagaaag gtcttctagt ttattcaact ttcctaggtc taggtctatc
    33061 caggtacaac cattgcccaa ctgcttttct aaaaccatct tttctcctta ttaaactccc
    33121 tctattgtac cacaaattac ttaaaataac aggtctagtc tgtgcgtgag aaattgctaa
    33181 caactgtgat atttcggtta gggacaaagt gaagggcttg ctcctcgcta cgaagctgtg
    33241 tcgtacgaat tcccacactg acaaccttac ccgatacagt aatcggtcca tttgtcagaa
    33301 cgacctcatc tcccacatcc agttgacgtt caaagaggat gaaaaagcca ttgatgacat
    33361 cagacagaaa gccttgggct cccataccaa tcgctacccc agcaatacca gctccagcca
    33421 gcaaactaga aactggcaaa cctaaaatcg acaaaatgca gtagagtaaa aagaaatata
    33481 gcgtataatt aaacacattt tctagtaaac gtgagatggt tttttggcgt ccgacatcat
    33541 gacgagacat ttttagagaa ggtttgacaa ttctctgcac catggtatga agcatttttt
    33601 tagcaatata aaatacaatc aaaagcagta aaagagaaat gaccttggtt agaatattct
    33661 cgataatggt tgtcacatct agcttttcaa tataagcctg aataaatttt tgcatataaa
    33721 actcctttat ttcattatac catattttca tcagtctcat tctccataaa tattcaaaaa
    33781 atagacagaa aattcttgat tttgtctatc atttatacta taatcataat cactacacaa
    33841 aaaggagatt attatgaaaa gaatcattca tgcttggaat aaggcaagcc ttgtcaagcg
    33901 tatcttgatt ggtatgcttt gtggggaatc ctaggactga cccttcctaa tctctcaggg
    33961 attgggctac tcggggattt attcgttgga ggtttaaaag ctgttgctcc tatcctagtc
    34021 tttgccctcg ttgccaatgc cctttccaac atcaaaaggg acaagatagc aatatgaaaa
    34081 ctgttgtttt cttgtatatc ctatgatagg gactttcgcc gctgctcttg tagctgtact
    34141 agcaagtttc atcgtcccta ttgaaattac cctaaatagt gccaatactg aaattgcacc
    34201 accagatggg attgggcagg tcctcagcaa cctcttgctc aaactggttg acaacccagt
    34261 caacgccctg cttactgcta actatattag aatcttatct tgggcagtca tttttggaat
    34321 cgctatgaga gaagccagta aaaatagtaa agaattgcta aaaactatcg ctgacgtgac
    34381 ttctaaaatt gtcgaatgga tcatcaatct ggctccattt ggaatccttg gtcttgtttt
    34441 taaaaccatt tctgacaagg gagtcggaag ccttgccaac tacggtattt tattggttct
    34501 attagtaacg actatgcttt ttgttgcccc tgtggtcaac cctttgattg ccttcttctt
    34561 tatgagacgc aatccttacc ctctagtttg gaactgcctc cgtgtcagcg gtgtgacagc
    34621 ctttttcact cgtagttctg cgactaacat tcctgtcaac atgaaactct gccatgacct
    34681 tggactcaac ccagatacct attctgtttc tatcccactc ggttctacta tcaatatggc
    34741 tggagtagcg attaccatta acgttttgac ccttgttaca gttaacactc ttggaattcc
    34801 tgttgacttt gccacagcct ttgtcctcag tgtggtagca gctatctcag cctgtgatgc
    34861 ttcaggtatt gccggaggtt ccctccttct tatcccagtt gcttgtagcc ttttcggtat
    34921 ttctaacgat attgccatac aaattgttgg ggttggtttt gtgattggtg tcatccaaga
    34981 ctcatgtgaa acagccctta actcttctac agatgtcctc tttaccgccg ttgccgaata
    35041 cgcagcaacc cgtaaaaaat aactcatcaa ggcaagcctg ctcatgtctt gtcttttacg
    35101 cttttattct aacttattag gaaattctta tgtctattag ccaacgtacg accaagctca
    35161 tcttagctac ctgtcttgcc tgcctgcttg cttattttct caatctttcg tcagcagttt
    35221 cggctggaat tatcgctctc ttgagcctat ctgatacgcg tagaagtact ttaaaactgg
    35281 ctcgcaatcg tcttttttct atgcttctag ctctggctat cggcgttcta gcttttcact
    35341 tgagcggatt tcatatctgg agtctcggcc tctatctggc cttctacgtt cctttagcct
    35401 acaagatggg ctgggaaatt ggcatcacac caagcacggt tttggttagc catctcttgg
    35461 ttcaagagtc aacctctcca gacctcctag tcaacgaatt ccttctcttt gctattggta
    35521 caggatttgc cttgcttgtt aatctctata tgccttcacg agaagaggaa atccagcact
    35581 accacacgct ggtggaagaa aagttaaaag atatcctcca gcgcttcaaa tactatttat
    35641 ccagaggaga cggacgcaac cgagcacagc tggtagcaga attagacacg cttttgaaag
    35701 aagccctcag actggtctat ttggatcact ctgaccacct ctttcaccag accgactacc
    35761 atatccacta ctttgagatg agacaacgac aaagtcgtat cctgagaaac atggcccaac
    35821 agattaacac ttgtcacctt gccgccagtg aaagcctgat cttagcgcaa ctcttttcaa
    35881 aaattgcagg tcaactgagc cagaccaatc ctgcttctga tttgctagat gaaattgaac
    35941 gttatctgga agtcttccgg aaccgcagtc tgcccaagac aagagaagag tttgaaaccc
    36001 gcgccactct tcttcaactc ctacgtgaag ccagaacctt catccaagta aaagttgatt
    36061 tttaccaaaa atatagacag taaaaaagaa aaccactaaa aaacagagct tgccagtatt
    36121 cttgaaaagt agtataatta ttgcatgcgc aatcatcttg tgacgcagag actgcccgtt
    36181 aatggacttt cttctattta tgactctaaa aagaaaggag acactatgac ctatttggaa
    36241 aaatggtttg acttcaatcg gcgtcagaaa gaaattgaaa gtctcttgga agagaccatt
    36301 gcccaacaga gcgagcaaag tctgaccttg aaagagttct acctgctcta ctatctggac
    36361 ttggctgaag aaaaatctct acgccagatt gacctgccag ataagcttca tctgagcccg
    36421 agcgcagttt ctaggatggt ggctcgcttg gaagctaaaa attgcggtct actcagtcgc
    36481 atgtgttgcc atcaagatag acgctctagt tttatctgcc tgacaaatga tgggcaaaag
    36541 acactggcct cgctacaaaa gactgtcgaa gaaagcttgg aagcaggttt ggatttcttg
    36601 atttaagatg attttaaaaa aagttgcgtg cgcaatcatt tttcttgaca ttctctttta
    36661 taaggagtaa aataaagtta gcattaaaca aaggagtttt aaatatgatt gaaattacct
    36721 atatagatgc cagcaagaac gaaagaactg tgactttcga gtcttatgaa gactttgaac
    36781 gttcgcaaca agcttgcctt atcggcgtcg cagactacta ccctgtccaa aaattaactt
    36841 acaagggtca taatttggac taccatggga cttatggaga tatcttcttc tatctcatga
    36901 aacaagattt aagccaatat aactaaaaaa aggagaaata caatggcaaa agcaattaca
    36961 gatgcaacat tcgaacaaga aacaaaagac ggtttggtct tagtagactt ctgggcaact
    37021 tggtgtggtc catgtcgtat gcaaggtcca atcttggaca aattgtctga agaactttca
    37081 gaagatgtct tgaaaatcgt taaaatggac gttgatgaaa atccaaacac agctcgtgct
    37141 tttggaatca tgtctattcc aactcttctc ttcaaaaaag acggccaagt tgtcaaacaa
    37201 gttgcaggtg ttcacacagc agaacaaatc aaggccatca ttgctgaatt gagctaatca
    37261 aacgagagac caagtacttt ctttggtctc ttttttcttg ctctttgcca tttttcaaaa
    37321 aatatgctag actatagtag attgaaacta gaatagtaca cctctacttc taaaacattg
    37381 ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt cttatttcat tttactatat
    37441 aagtagaata ttacgatgtt tgggatatgc catcgctaaa aaaactcgat ttggtatttt
    37501 ttagctccct aatgggagct ttttgcgtgc tctgaacatt tcccattttg gaaggagtac
    37561 tatgaaacgt caatcagcct tggtcgtctt tagtggtggt caagattcaa caacctgcct
    37621 tttctgggcc atgcaacact atgaaacagt cgaagctgtc acctttgcct acggccaacg
    37681 tcatcacctc gaaattcaaa ttactagaga aatcgctaag gaacagggca ttcgtcacca
    37741 tatcctcgat atgtctctgc tgggacaaat cactgctcag ccagactttg cgacgattca
    37801 tatttcctac attcctgaca agctctgtgt cgagtcaaaa tccctcaaac tatatctatt
    37861 tagctaccga aatcacggag atttccacga aaactgtatc aacaccatcg ggaaagactt
    37921 ggtcaacttg ctagaccctc gctatttaga agtctgggga aaattcactc cgcgcggtgg
    37981 catttcaatc gacccctact ataactacgg taagcaagga actaagtatg agggcttggc
    38041 agaacaacgc ctcttccaac acgaccttta tccagagaaa attgacaacc gctaaagtca
    38101 tactcaatga aaatcaaaga gcaaactagg aagttagccg caggttactc aaagcagtgt
    38161 ttgaggtggc agatagaact gacgaagtca gcttaaaaca ctgttttgag gttgcagata
    38221 gaactgacga agtcagtaac catacctagg acaaggtgaa gctgacgtgg tttgaagaga
    38281 ttttcgaaga gtatcatacg aaaaagccct gttcctcaag atgaggagca aggctttttg
    38341 agtttcaatt attcttctgt tccaaggaaa ttttttgcaa caagggctgc aagaactcca
    38401 ccagcgattg gtgcaaggat gaaaatccaa acttgttgaa gggctgcgcc gcctaccaag
    38461 acagctggtg ccaagctacg agctgggttt actgaaagtc cagtaatctt caatccgaca
    38521 agaatcatcg ccatcaatga caaaccgatt accaaaccag caatcgcgcc attgccctta
    38581 ctttctgaag tcacagtcat gataactaag acaaacaaga aagttgcgat gacttcaaac
    38641 aagaaaccac caaagacagt gacaccgttt gccaaggcat tttcaccaag actagcagtt
    38701 gacatacctg aattacccaa gaggaagaag actgcgccag aagcgatgaa agctccaaca
    38761 acctgaccaa ggatgtagtt tacaagttct gaagatgaca aacgtttgtt tacaaacata
    38821 gcaatcgaaa cagccggatt caagtgagca cctgaaacag ttccgattga gtaggctgcc
    38881 accacgattg ccaaaccaaa ggcaaaggcg attccaaggt gaccaaggcc atcaagacca
    38941 tttccaaaaa caacagctcc tgtcccgacg aatacaagca tgaacgtacc gattaactca
    39001 gcaacaaatt ttttcatttt ctttctcctt ttttcaaaaa ctagatacta gtctatcaaa
    39061 agtaggaaag ggtttcaaga aaattgattg gaaatttttt gaaaatcata gaactattag
    39121 ctaatctcta gtattgaaaa gactggatag cttctttcaa ctcatcttgt aaactatttc
    39181 tctggtcaag ttggacatag acttccaaca gacaggttct gaagttggaa aatttgtaaa
    39241 aatcctccct ttcttctatc ggaaaatcaa cagtttttat ccaagaagct acttgttctt
    39301 gcgctaactt cccttgtaaa ataggttcat agatcactct tgctaaacgc caatcctcat
    39361 catctgtaaa gcgaatcgac attcttttaa atagttggcc aagtatatca aatacttcat
    39421 gaactctgtt tttaggaaag tctggatgac aaaccacctc tttcagtaaa tcggctccat
    39481 gtgcaaaagc gtgaacccaa ccatactgac ttgagaaacc tgttgtatcc ttttcttttg
    39541 aaagatagtg caagccttga tttaaaagga cattacgaat ttctgattgt aatccctgat
    39601 aaaaaaccga ttgctggtta gcatctacag acaagagatt tgcataaaca agtgccctaa
    39661 aagaacgttc aagtgttgac aagcctacct tatcaatctc tttatctaac cctccatcag
    39721 ctaagaccac ctcagcaatg aaatgaaatt gctcctgtgt aaatagctct tcctgaatcc
    39781 ctctagcaaa gcttgtaaaa acaagatcat cacgaatttc tggagaagga tctcccaaat
    39841 gatcaagcaa ccactggatt tcctcctggt tataatttgg tttttcttct gctatttttc
    39901 ttagtaaatc ttgatacatg gtcaatacct ctacatttct agcaactgtt caaaaaggca
    39961 gtcttaaatg accttaccaa tttgtaaaat taagttaaaa agaaaaagac atttatattc
    40021 agagaaacag catatttctg aaaagatata taaatgattt attccatatt acaacaaata
    40081 aacttgtaat gatagaacct tatcacaaaa atcacattcc tgtctcaaaa attgcgaaaa
    40141 actagttata ataaagtgaa ataaaaacta tacaaattga ttagggaatt taaaacaatt
    40201 tctaacaata tttaaaaact gaaccgtact atttcaactt ccataaatta caatattgat
    40261 aggcacagtt cccatacctg tccaaattcg aataacgttt agtataaatt agaatatgac
    40321 tacaacatca caaataatta gactatctat aatatctacg atgtaacata tacataggaa
    40381 gcaccgttat caagagcgcc aaggctatca accagataag atgaagatac aaacctgtca
    40441 cctcacctcc ccatataata cgaatcatgc gggtagcgtg atacaaggga gaaaaccaag
    40501 tcaaatcacc aagtattggg ggcaaggaag taatgggaaa gaaggtatct gaaaacatat
    40561 aaagaggacg gattaccaaa acattgtagt aattcagaaa ttccctagac ggcgccaagt
    40621 aggtaaagat tagtcccaaa acaccaaaca aataacccac tataaataaa atcagaggaa
    40681 tcaataacat caagacatga aaatgcgctg tgataagcat ggaaatcagc caaaaaatcc
    40741 caccgaaaat cactgcacga atacctgccc agatagcctg acctaccaca atatcattcg
    40801 tattgattgg cgtcatcaac atagcatcat aagtcttttc aatcttatac tggataaagg
    40861 cattgaccgt tgtttctgcg gtggccgcag acatggcagt cgcagcaatt aaacctgtaa
    40921 tgacaaaatc acggtagagc ataccgttaa catgcgtcaa ataagcacca actccaaatc
    40981 ccattgctaa aagataaaag agggggtcga taaggttggg gacaattgaa attttaaata
    41041 aatttctaaa actcatgtag ttgcgtacca caacgtgtcc gatggagtga aatgataact
    41101 taaacatgca agtcctcctt ctctgtccca gtcaaccccc aaaaaagcgt ctcaaggttg
    41161 tcagcatcat acttgatgag caagtcttct acagttcctt cttctttgat agtcccttgg
    41221 tggagcatca gcaccctatc tgtcaaatat tcaatctcat tcatatagtg ggaagtaata
    41281 atgatagaaa cacctaattc cttcaattcc aaaagtttat cccaaataat attgcgggat
    41341 tgaatgtcta aaccaactgt cggttcatct aaaatgataa tatcaggccg attgatgaga
    41401 gctcttgcca agacaagacg tcgtcgcatc ccacccgaca gctgattcac catcttttgc
    41461 gcatgtttgc tcagttgaac aaaatccaag agagaatcga ttctcttcct aagttcgaca
    41521 gatgagatac cataacatag accgtgagca aaaagattat cataaacatt caaggtcatg
    41581 tccagcatat cctcctgccc tacaataccc agacaagatt tactcttacg acgattggtt
    41641 tcaatatttt gccccaagat atcaatctct cctgaggaaa ttgaggtcag tgagtaaatc
    41701 atctttaaag tggatgtttt gccagcaccg ttgattccca agatacccaa acactctccg
    41761 tctcccaatt caaagctaat tcccttgaca gcttcataag aaccatattg cttttttaga
    41821 tttttaacac ttaacttctt cactctttct ttcccccaca aatagagcat gttggatact
    41881 ttgttaattc atctcacttt tgaaaaaatg ttgagaatgt aatcttaaga ttaacgtcct
    41941 tcaactgtgg atactgctgc aattactttt gtaattttac ctccatttaa actcagacaa
    42001 taaaatttaa aatattctct agtaaaacat ttttaaaatc tatttttctt gtgctttaat
    42061 tatagtataa taaaagatag aaaatcatcg atatatgaaa tttggagaaa atttttatgg
    42121 aaccagatat tttcatcatc acaaaactct tatcagaccc ttctcggatg cacattttag
    42181 atattctaat ggatggaaaa gctcacacgg ttaacgaaat tgccagcttt accaaaatca
    42241 agcaacatac tgtcagctat cacctcaaat tacttaccga agcgcaggta accactctac
    42301 aaacctatgg acgttttcat tattattctt taaaaagtgc tgccattgca gaaatgctgg
    42361 aatttctcag cttctactct cctcagcgtg atgtcaaaag ttataaacaa cacattcaca
    42421 aaaaggaatt aaaggtcgct cgcacctgct atgaccatat tgctggtgag cttggcattt
    42481 ccattaccaa ttatctcttg caagaaaatc tcctcagcga atcagaaaaa gacttccaac
    42541 tcactgaagc tgggaagtct tatttccaaa gaaaattaca cattgatacg gatgaattga
    42601 aaaagaaaaa acggaaattt tgccctaaat gtttggattg gagcgaacgt aaaaatcatg
    42661 tcggcggagc tctcggcaat gctcttttag aatttttcag tgaaaaacaa ttggtcatcc
    42721 ctgcacaaac gccacgttca cttaccatta cagagaaggg caaagaattc ctcgaaaagg
    42781 aatgggggat ttaaacatgg acttttaagc aaataactgt ccatacccat tctataacaa
    42841 cctctctatc cccttactcc cccaactcag cactgtaggc gataatctgg tcaactgtgt
    42901 cagacaagaa ttggatggta tcacggagtg gtttgtctgt tgaaatatca gcaccgataa
    42961 tcatggctga ctcaagtggt gtcttgctac cacctgattt gaggagattg agccagtctt
    43021 cagctccagt ttctgagttt ttaagatgaa ggtaaccagc tgtcgagatg acaagaccag
    43081 cagagtaagt gtaactatac aagcccatat agtagtgagc ttggcgcatc caagtcaaag
    43141 ctgcatcgtc gtcgatttca atggcatcgc cccaaaaatc tgtcaaaact tccttcataa
    43201 tgctgttgag tttgcttgct ccgaaggttt ctccttcttc aatcaatgta tacaccttac
    43261 gctggaaggc ggcttccaag aggtgggtga tgaaattatg gaagtaggtg tctgtcaagc
    43321 gatgagccag agcgaagcgt ttttgacgtg ggtcattaga ctggttctct aagtaatcac
    43381 tgagtagcaa ttcattgaag gtcgacggtg cttcaacata ataggtcgac atgtgggcgt
    43441 tgaaatagct ttggtgattg tctgaaaaga tgaattgacc agaatgcccg atttcatgaa
    43501 tcaaggtata gacatcgctc aaacggcctg tccagctcat gagtacataa gggtgtacgc
    43561 gatatgggtc cgccgcataa ccaccggaat ccttgccact gttagcagca aagtccaccc
    43621 agcgctcttc ttggtaacga gcaacttcct gacaatattc ttgccccaaa ggttctaccg
    43681 acttcatgac caaatcatag gcatcgtcaa tagtcacttc aggattgagg gcgctgtcca
    43741 agtccaattt ccagtctgca aaggtcatct tttcaagacc atttaccttg gcaacatgct
    43801 tgaggtatct ctgagcgact ggtgcaaagt ccttcatgat gaggtcaatc tggcgatcaa
    43861 acatgacacg gtccacttct tgttcagcta gaagatagtc aaagacagag tcatatccct
    43921 tcatatcagc caagagtttt tcagacttga cctgagccag ataggctgct gcagccgtat
    43981 tttggtgctt acgaagtccc tctgagaagg aacggaagga tttctcacga acctcagcat
    44041 cctcgtgatt ttggtagaaa ttctcatagg tgacaaagct gtttttatag gtcttgccat
    44101 gggcttcaaa gtcagccatt tcaaaatccc cagctcgcat cttagtataa atgtcctgcg
    44161 gactatagaa aacttcaccg agatttgtca aggccttctc cacatctgcc cctaagtagt
    44221 gggctttttt gattttagcc tgacgaatgg cagctgttaa atgtggcaat ttacccaaac
    44281 ggtccaagac ttcctcgtct gctgccacca aggcatcgtc aaagaaggtc aaggctacgc
    44341 tggcagctgt ttcaaattcc atcccagctt gggcaatatt ggcaaattcg tcattgctat
    44401 agtccgtcgt ctgaggcata aaagcatagt tgccaatatg gctcatctga atgtagatct
    44461 gttccaattc cgcaaaggcc ttctcgaaat cctcaaaagt gtgaagattg cccttgtaat
    44521 cacggctaaa ctggttgatg tcttcgcgag ctttctcgat tgcacgcaag aaatcctcac
    44581 ggtcttggta tagggctgtt aagtcccaga gttccttctc tggaaattct gaacggtgtt
    44641 tttgttccat tttcttcctc ttatttctct aattctacta aaacactaag ggctgataag
    44701 gcgtaaagcg gtgctgtttc tgctcgcaaa atacgaggac ctaggcctac caaaacggct
    44761 cccttagctt caaaactttc gatttctgca ggtgagagac cgccttctgg accaaagata
    44821 aagagcagtt tggctcctgt ttcaagacca gtgactgctt gcagaagcgc agcggcttct
    44881 ccttctttac ctgattcttc ataggctact atgatagagt caaactggtc cagctgagtt
    44941 agaaaatctg cttttttctc gaaaagttta atacttggta caatattacg cttgctttgc
    45001 tcggctgctc caagggcaat tttttctagt ttttcaactt ttttacccaa tttcttgcca
    45061 tcccacttgg caactgacca gtctgcagga aaggcccaga tttggctagc acccagttcg
    45121 gttacttttt gagcgatgaa ctccagcttg tctcccttgg gaaatccaga tgcgatggtc
    45181 acttgaactg gtagttccac attgtcattt aattcttgga ccaactcaaa ctgacgattt
    45241 tccatatcca gcacgcgcgc caagcgcttg atgccatcat caaagactaa ggtaacctca
    45301 tcctcttctt tcaagcgcat aacctgaaac atatgcttac tggtttcctt gttctcgata
    45361 gtgacaggag agatagcact gccttttaca aaatactgct gcatgctagc ctccaatcac
    45421 accagagata tccttggttt tcttaaagac acaggcattc cattcccctt gaaccatgtg
    45481 agtttcgagg aaaaatccag ctgattcagc caactcgcgc accatgtccc acttatcctt
    45541 gataatgcca ctcatgatca ggtaaccttc atccttaacc aagcgataag catcctctgt
    45601 cagatgaatg aggatatccg ccaagatgtt tgccacgatg acatctgctt caatctccac
    45661 gcctttaagc aaatcgcctg ccgctacatg gatattttcc attccagggt tgagctcaat
    45721 attttcctga gccacacgaa ctgccacatc atccaggtca taggcgaaaa tttctttagc
    45781 ccccagaagc gagctggcaa tagagagaac ccctgaacca gttcccacat ctagcaccgt
    45841 ttcgccacca cgaagaacct gttccaaggc aaaaatgctc atcttggtag ttgggtgggt
    45901 tcccgtacca aaagccatgc caggatccag cttgataatt ttttctcccg cagtcgcctc
    45961 atagtctgtc caagagggaa cgatggtcaa atcatgagtg atacgagctg gctcatagta
    46021 tttcttccag ttatctgccc agtcttcctc agccaaggca gtcgtaccta tttttaactc
    46081 tcccaaatcc ataaaatccg tcaattctga tatgcgagcc tgcaagtccg cctcaaccac
    46141 tgtcacatcc accgtgtcag ggtagtaggc tgtcactacg atttcttctt gctgctcgac
    46201 ctctgggaaa atctcgccga agcggtcaac atttcccaca tagtccatac tgtcttcaat
    46261 cgcaacacct tgcgctccca gctcaatcaa gagattggaa accaactcct ctccctcacg
    46321 cttcactgta acttttaact cttgccatgt ttccatcatt aagataccaa gcccgtaaaa
    46381 cacaaaacca aaataggaaa ttctctgaag acgcttgtgt ctaagagaag tttatctttt
    46441 tggcacagtg tttagggcgg gttcagttta gaaatttaac tgaaccatcc tttctaatca
    46501 cttactttta aataatcttt taatctctct tgcaactgag gcacaacttg actggaacta
    46561 agaaattcct caacattcat cagctgatag ccctgtcctt catctccgaa gatgatattg
    46621 tcaaattgtt cttgtcttag ctgaccaacc ataaagaccg atttcttgcc tttaaaaatt
    46681 acgctaggat aaatcttgct ccaaagcaga cagtcttcat ctaaatgaat tcccagttcc
    46741 tcataaactt cacgccgagc gcattcaaaa gggctttcgt ccccttcacg gccaccacct
    46801 ggcaactccc acatgttggg acaagggata tcgtccttgt catcacgcaa aatcgtcagt
    46861 agcttatccc cacaaaagag ggcaatcttg caaccttgga aatcagaaat ttctagttcc
    46921 atcttcagtt ccttctaaca tttccttttc cagctctgct aacaagtttt cataatagcg
    46981 tttctcgtcc ctcaacattc gactactatc cattttctgt ctagcaatct tgagagcctt
    47041 acgagttcga tctacatctt tcttcacctt taattgatac caggcttgta tcacttgaag
    47101 attggacagt ttgagagaca gaaacgattt gacctgtcga atactagcat attgctccgc
    47161 ttgctcaaaa tctccttcca acaaggcgat atgaagcagg gatagttggg caactgtctg
    47221 catcatcgga gtagttgtcc tctcaagtaa tgcttgaaac tgctgtttag ctacttcttc
    47281 cttcccttcc aaaatggaaa cttcaccttg catacctaat acaccatccg caaaactccc
    47341 tcgtgcatcc tcaggaactg cttgaacaaa gtctttcaaa tcatattctt gaggagccag
    47401 caaagtttga gcagaatgtc tcaataccag gtaggcgtat ttggtatttt cagggtgtta
    47461 tagtaattcc caaatttttg ctccatcggt gatgtcgact ggcaaaatgt tatttaggaa
    47521 gaaagataaa ttaagaaaaa tccaagtccc tgcaaaatac cagcttcttg tcaaaaagcc
    47581 aaacactatc gccaataata tcaagccgag atgaaccatc aagcctcctg aaagcatcag
    47641 gatgattctt tgatcgcttt catcctcttt taaaccaatg tattgagcac caacattttt
    47701 cagaatggct gttctactaa gatgaaacct gcctgacttt ttggtcaaaa taaaatgtcc
    47761 taatccaaaa gccaccagcc gatagcctgt caagtagcca caaaaagcat gacccagctc
    47821 atgaagaata aagattaaat acatgcttag aagagcgaag gcataaccaa aagtaaaggc
    47881 taaaactgcg gaatacccca actctgcaaa tgcgattgtt ccacaagcaa aagctagcat
    47941 aataaagaca acagctagca cataaaccaa ataagtccca attttcttca taacacctcc
    48001 aaccaactcc tagtatcttg gataaggata aaattctccc tcttccaagc caacttttcc
    48061 ttcttcaaag acttcttgat tccattccat aacaaattcc tctgcttctg gatcttccaa
    48121 aaagtccatg agggtatcta gcccaacctc cgcagtatct ttgaggaaaa gggcaaaata
    48181 agctaaaaac tcgcgagaaa atcctttttt aggtagataa gggataaccg ttaaatagtc
    48241 ttctgcattg acggttgact tggcaggatt gtagaaaagg accgcttcct caaaaagaat
    48301 gtcatctgat gaaacctctc cgtcttcatc caccatctcc acacctgcag cattttgcgc
    48361 ttccaataga aaactcactt ctaccgcatg gttgcgtttg tcccagctaa tctcaaagtc
    48421 aaagggaaag ttcttgtcca actcttcctc taaaacatct aaaaatccgt atgttgccat
    48481 tttgtcctct ttctatgcga ctctttaatc gccccgattg ctcggaaata tgctaaaata
    48541 gatactacca tcttaccaca aaattatttt atgtcctaat tataccatat tacctcattt
    48601 aaacccttgg tatcagtgat tttcttaaaa gtctgatttc ttcatttctc ataaaaatca
    48661 atataaaaag ccctcgaaag ggctaataaa tctataaaat caataggcga gtaactagca
    48721 caagtggacg tgctttttta ttgactatta ccacgatacc acgcttaatc ttaggcttga
    48781 actttcttat ctgcaatagc gtctgtcaaa gtctgagaaa agttaagtcc catttctcgt
    48841 cccaacttat ctgcccattt tggtatggtc aaagtctttt taatgggttc ctgacttcct
    48901 aggtattctg atacatcaac agataccata gaaataaaag atttatcaag gtcataggtt
    48961 gacacgaaat cttcatcatc tttaaaagga tcattatcaa ttaaagacaa gctattgata
    49021 tctgatggct gaggtaactc tccatcactc tctatcaaat ctgcaacagt tatccctagc
    49081 cactccgacc ccatagccaa agcctcagaa atcccctctc cttgtgtagc tgagtattca
    49141 aaatctggga aatggacaaa ataagtcgct tctgttccgt ctgtgtcgtc ataataaaat
    49201 aaagctggat acgtaactaa catttcacta cctccatatc aaaaagcagg gactgaattt
    49261 tacaacccag cttgctttct tatccctctt tcagtgtact tattcagctc accatgaggg
    49321 attgtgatag gtctttcccc ttgcttctcg attttaatat gggaaccttt accgcctcta
    49381 gtctttatca accatgggcc gtaaggagtt taaccatctc tttttgtgtc ataggcatag
    49441 cgcttttacc tcctgacaac accattataa cacgtgttac acgtattgta aaggagtgat
    49501 acttattatt ctattataca taaaagcccc tagatgtggt tctaagggaa gccaatttat
    49561 tcatacctat ttttctaatg agtagtaaaa actgcttctt tatcgagcaa ttcatcatct
    49621 gtatagtcaa ttgtaaaagt atctcgatct aagacagatt gaggcggagt tgaatgaatc
    49681 ataggaacac tgcgtactct atatttttta tctccaattt ttacaaactg atactcttcg
    49741 aaaatcaaat tcaaaccacg tcaacgtcgc ctt
//
LOCUS       DAVBNN010000008        49363 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBNN010000008 DAVBNN010000000
VERSION     DAVBNN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.008"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(78..536)
                     /locus_tag="VQ847_000454"
     CDS             complement(78..536)
                     /locus_tag="VQ847_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3049848.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(533..973)
                     /locus_tag="VQ847_000455"
     CDS             complement(533..973)
                     /locus_tag="VQ847_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3049849.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1179..3128
                     /gene="mutL"
                     /locus_tag="VQ847_000456"
     CDS             1179..3128
                     /gene="mutL"
                     /locus_tag="VQ847_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3049850.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3453..3920)
                     /locus_tag="VQ847_000457"
     CDS             complement(3453..3920)
                     /locus_tag="VQ847_000457"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3049851.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3921..5126)
                     /locus_tag="VQ847_000458"
     CDS             complement(3921..5126)
                     /locus_tag="VQ847_000458"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3049852.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5146..5781)
                     /gene="ribE"
                     /locus_tag="VQ847_000459"
     CDS             complement(5146..5781)
                     /gene="ribE"
                     /locus_tag="VQ847_000459"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3049853.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5766..6866)
                     /gene="ribD"
                     /locus_tag="VQ847_000460"
     CDS             complement(5766..6866)
                     /gene="ribD"
                     /locus_tag="VQ847_000460"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3049854.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7000..7114)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7271..7864
                     /gene="ruvA"
                     /locus_tag="VQ847_000461"
     CDS             7271..7864
                     /gene="ruvA"
                     /locus_tag="VQ847_000461"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3049855.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7874..8437
                     /locus_tag="VQ847_000462"
     CDS             7874..8437
                     /locus_tag="VQ847_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3049856.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8434..9111
                     /locus_tag="VQ847_000463"
     CDS             8434..9111
                     /locus_tag="VQ847_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3049857.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9248..10279)
                     /locus_tag="VQ847_000464"
     CDS             complement(9248..10279)
                     /locus_tag="VQ847_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3049858.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10534..11217)
                     /locus_tag="VQ847_000465"
     CDS             complement(10534..11217)
                     /locus_tag="VQ847_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3049859.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11229..12173)
                     /locus_tag="VQ847_000466"
     CDS             complement(11229..12173)
                     /locus_tag="VQ847_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3049860.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12305..15136
                     /gene="uvrA"
                     /locus_tag="VQ847_000467"
     CDS             12305..15136
                     /gene="uvrA"
                     /locus_tag="VQ847_000467"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3049861.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15129..16190
                     /locus_tag="VQ847_000468"
     CDS             15129..16190
                     /locus_tag="VQ847_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3049862.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16322..16720
                     /gene="spx"
                     /locus_tag="VQ847_000469"
     CDS             16322..16720
                     /gene="spx"
                     /locus_tag="VQ847_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3049863.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16786..17355
                     /locus_tag="VQ847_000470"
     CDS             16786..17355
                     /locus_tag="VQ847_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3049864.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17442..17708
                     /locus_tag="VQ847_000471"
     CDS             17442..17708
                     /locus_tag="VQ847_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3049865.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17712..18131
                     /gene="ruvX"
                     /locus_tag="VQ847_000472"
     CDS             17712..18131
                     /gene="ruvX"
                     /locus_tag="VQ847_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3049866.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18147..18452
                     /locus_tag="VQ847_000473"
     CDS             18147..18452
                     /locus_tag="VQ847_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3049867.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18758..20008
                     /locus_tag="VQ847_000474"
     CDS             18758..20008
                     /locus_tag="VQ847_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3049868.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20005..20547
                     /locus_tag="VQ847_000475"
     CDS             20005..20547
                     /locus_tag="VQ847_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3049869.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20693..22225
                     /gene="cls"
                     /locus_tag="VQ847_000476"
     CDS             20693..22225
                     /gene="cls"
                     /locus_tag="VQ847_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3049870.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22303..22446
                     /locus_tag="VQ847_000477"
     CDS             22303..22446
                     /locus_tag="VQ847_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049871.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            22483..24021
                     /locus_tag="VQ847_000478"
     CDS             22483..24021
                     /locus_tag="VQ847_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3049872.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVGLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24141..26348
                     /gene="nrdD"
                     /locus_tag="VQ847_000479"
     CDS             24141..26348
                     /gene="nrdD"
                     /locus_tag="VQ847_000479"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3049873.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26360..26500
                     /locus_tag="VQ847_000480"
     CDS             26360..26500
                     /locus_tag="VQ847_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049874.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26544..27050
                     /locus_tag="VQ847_000481"
     CDS             26544..27050
                     /locus_tag="VQ847_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3049875.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27043..27633
                     /gene="nrdG"
                     /locus_tag="VQ847_000482"
     CDS             27043..27633
                     /gene="nrdG"
                     /locus_tag="VQ847_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3049876.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27630..28247
                     /locus_tag="VQ847_000483"
     CDS             27630..28247
                     /locus_tag="VQ847_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3049877.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28502..28810
                     /gene="rpsJ"
                     /locus_tag="VQ847_000484"
     CDS             28502..28810
                     /gene="rpsJ"
                     /locus_tag="VQ847_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3049878.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29027..29653
                     /gene="rplC"
                     /locus_tag="VQ847_000485"
     CDS             29027..29653
                     /gene="rplC"
                     /locus_tag="VQ847_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3049879.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29678..30301
                     /gene="rplD"
                     /locus_tag="VQ847_000486"
     CDS             29678..30301
                     /gene="rplD"
                     /locus_tag="VQ847_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3049880.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30301..30597
                     /locus_tag="VQ847_000487"
     CDS             30301..30597
                     /locus_tag="VQ847_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3049881.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30615..31448
                     /gene="rplB"
                     /locus_tag="VQ847_000488"
     CDS             30615..31448
                     /gene="rplB"
                     /locus_tag="VQ847_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3049882.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31552..31833
                     /gene="rpsS"
                     /locus_tag="VQ847_000489"
     CDS             31552..31833
                     /gene="rpsS"
                     /locus_tag="VQ847_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3049883.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31845..32189
                     /gene="rplV"
                     /locus_tag="VQ847_000490"
     CDS             31845..32189
                     /gene="rplV"
                     /locus_tag="VQ847_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3049884.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32202..32855
                     /gene="rpsC"
                     /locus_tag="VQ847_000491"
     CDS             32202..32855
                     /gene="rpsC"
                     /locus_tag="VQ847_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3049885.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32859..33272
                     /gene="rplP"
                     /locus_tag="VQ847_000492"
     CDS             32859..33272
                     /gene="rplP"
                     /locus_tag="VQ847_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3049886.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33282..33488
                     /locus_tag="VQ847_000493"
     CDS             33282..33488
                     /locus_tag="VQ847_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3049887.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33513..33773
                     /gene="rpsQ"
                     /locus_tag="VQ847_000494"
     CDS             33513..33773
                     /gene="rpsQ"
                     /locus_tag="VQ847_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3049888.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33799..34167
                     /gene="rplN"
                     /locus_tag="VQ847_000495"
     CDS             33799..34167
                     /gene="rplN"
                     /locus_tag="VQ847_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3049889.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34245..34550
                     /gene="rplX"
                     /locus_tag="VQ847_000496"
     CDS             34245..34550
                     /gene="rplX"
                     /locus_tag="VQ847_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3049890.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34574..35116
                     /gene="rplE"
                     /locus_tag="VQ847_000497"
     CDS             34574..35116
                     /gene="rplE"
                     /locus_tag="VQ847_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3049891.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35134..35403
                     /gene="rpsN"
                     /locus_tag="VQ847_000498"
     CDS             35134..35403
                     /gene="rpsN"
                     /locus_tag="VQ847_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3049892.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35688..36086
                     /gene="rpsH"
                     /locus_tag="VQ847_000499"
     CDS             35688..36086
                     /gene="rpsH"
                     /locus_tag="VQ847_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3049893.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36278..36814
                     /gene="rplF"
                     /locus_tag="VQ847_000500"
     CDS             36278..36814
                     /gene="rplF"
                     /locus_tag="VQ847_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3049894.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36898..37254
                     /gene="rplR"
                     /locus_tag="VQ847_000501"
     CDS             36898..37254
                     /gene="rplR"
                     /locus_tag="VQ847_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3049895.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37272..37766
                     /gene="rpsE"
                     /locus_tag="VQ847_000502"
     CDS             37272..37766
                     /gene="rpsE"
                     /locus_tag="VQ847_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3049896.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37738..37962
                     /gene="rpmD"
                     /locus_tag="VQ847_000503"
     CDS             37738..37962
                     /gene="rpmD"
                     /locus_tag="VQ847_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3049897.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38107..38547
                     /gene="rplO"
                     /locus_tag="VQ847_000504"
     CDS             38107..38547
                     /gene="rplO"
                     /locus_tag="VQ847_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3049898.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38560..39870
                     /gene="secY"
                     /locus_tag="VQ847_000505"
     CDS             38560..39870
                     /gene="secY"
                     /locus_tag="VQ847_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3049899.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40021..40659
                     /locus_tag="VQ847_000506"
     CDS             40021..40659
                     /locus_tag="VQ847_000506"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3049900.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40776..40994
                     /gene="infA"
                     /locus_tag="VQ847_000507"
     CDS             40776..40994
                     /gene="infA"
                     /locus_tag="VQ847_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3049901.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41019..41135
                     /gene="rpmJ"
                     /locus_tag="VQ847_000508"
     CDS             41019..41135
                     /gene="rpmJ"
                     /locus_tag="VQ847_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3049902.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41153..41518
                     /gene="rpsM"
                     /locus_tag="VQ847_000509"
     CDS             41153..41518
                     /gene="rpsM"
                     /locus_tag="VQ847_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3049903.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41536..41919
                     /gene="rpsK"
                     /locus_tag="VQ847_000510"
     CDS             41536..41919
                     /gene="rpsK"
                     /locus_tag="VQ847_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3049904.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41962..42897
                     /locus_tag="VQ847_000511"
     CDS             41962..42897
                     /locus_tag="VQ847_000511"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3049905.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42909..43295
                     /gene="rplQ"
                     /locus_tag="VQ847_000512"
     CDS             42909..43295
                     /gene="rplQ"
                     /locus_tag="VQ847_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3049906.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43560..43826
                     /locus_tag="VQ847_000513"
     CDS             43560..43826
                     /locus_tag="VQ847_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3049907.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43836..45173
                     /locus_tag="VQ847_000514"
     CDS             43836..45173
                     /locus_tag="VQ847_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3049908.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45417..46109
                     /locus_tag="VQ847_000515"
     CDS             45417..46109
                     /locus_tag="VQ847_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3049909.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46212..47857)
                     /locus_tag="VQ847_000516"
                     /pseudo
     CDS             complement(46212..47857)
                     /locus_tag="VQ847_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(47847..48470)
                     /locus_tag="VQ847_000517"
     CDS             complement(47847..48470)
                     /locus_tag="VQ847_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049910.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(48456..48578)
                     /locus_tag="VQ847_000518"
                     /pseudo
     CDS             complement(48456..48578)
                     /locus_tag="VQ847_000518"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(48555..48925)
                     /locus_tag="VQ847_000519"
                     /pseudo
     CDS             complement(48555..48925)
                     /locus_tag="VQ847_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48938..49306)
                     /locus_tag="VQ847_000520"
     CDS             complement(48938..49306)
                     /locus_tag="VQ847_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3049911.1"
                     /translation="MTVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
BASE COUNT        14867 a         9321 c        10871 g        14304 t
ORIGIN      
        1 atttcactat agtaaggtgc agcaggataa agaaaaaccg agaagtttct ttctcggatt
       61 tgcttattat gaggttccta ttttctatgc tccaagagtt gattgatgtg atctactttt
      121 ttagcctctc ttttatagag aatagcccag atgatgagat agacaatcgc aaactcgata
      181 atgagctgga ggtagaaaat ccagtggaaa gggaaccaac cagcaagagt tgctagtggg
      241 acaaagccag ccagcataag gaagaaatga gtcagagtgg cacgaagcat gctccagtca
      301 cggctgaata agcggttgcc aaagttgaag agcataccga tggctgccca gataagtgtg
      361 cagtagagca agaccagggc accgtgaacc tgatgctgat ccatcacttg gccgatgaga
      421 gagtagggat ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa gaggatggag
      481 aggatgaggc cgataagaac accggcagct gcatcgtgaa atacttgttt tttcatagtt
      541 ctaatttctc cttgatggtt tttagataac ggcgtgaaga gtaggtgaag ctttcgtttt
      601 tcaagaaaat ttctaccaga ccgtttggcg tgagcttgag gtgagagatg gaatcgatat
      661 tgatgatttc tgattgggaa atttggataa aattggttgg caagagttta agaacctgat
      721 agagtcgcaa atcaatgctg taggtctgac tcgcggtttc tgctagaacc ttccgattct
      781 cgatatagaa gcgctgaatc ttgccaatct caactagata gacctgatca tcgattttcc
      841 ctttgatttt ttctctttgg tccagatttt ctgcgaactc gatgactttc tggactttat
      901 ctgtcggctg aggtgcttgg acaatcagct tttcctcctc gtaagtctca ctaatctgta
      961 gttctacttt catagttttc tctccttttc agttatacaa ggttgtgatc acttcctgta
     1021 tatccttatt aaacactatt ttatagccca tggcaaggaa ccttgtctat gtggagggat
     1081 tgggctccta tgtggtggag cttttctgtt ctttctgaaa tatggtataa tagcactaat
     1141 taatttctag gaaaatagat acagaaaggg gctgaaagat gtctcatatt attgaattgc
     1201 cagagatgct ggcaaaccaa atcgcagctg gggaggtcat tgaacgtcct gccagtgtgg
     1261 ttaaagagtt ggtagaaaat gccattgacg cgggctctag tcagattatc attgagattg
     1321 aggaagctgg tctcaagaag gttcaaatca cggataacgg tcatggaatt gcccacgatg
     1381 aggtggagtt ggccctgcgt cgccatgcga ccagtaagat aaaaaatcaa gcagatctct
     1441 ttcggattcg gacgcttggt tttcgtggtg aagccttgcc ttctattgcg tctgttagtg
     1501 tcttgactct gttaacggcg gtggatggtg ctagtcatgg aaccaagtta gtcgcgcgtg
     1561 ggggtgaagt tgaggaagtc atcccagcga ctagtcctgt gggaaccaag gtttgtgtgg
     1621 aggatctctt tttcaacacg cctgcccgtc tcaagtatat gaagagccag caagcggagt
     1681 tgtctcatat cattgatatt gtcaaccgtc tgggcttggc ccatcctgag atttctttta
     1741 gcttgattag tgatggcaag gaaatgacgc ggacagcagg gactggtcaa ttgcgccaag
     1801 caatcgcagg gatttacggt ttggtcagtg ccaagaagat gattgaaatt gagaactctg
     1861 acctagattt cgaaatttca ggttttgtgt ccttgcctga gttgactcgg gctaaccgca
     1921 attatatcag cctcttcatc aatggtcgtt atatcaagaa cttcctgctc aatcgtgcta
     1981 ttttggatgg tttcggaagc aagcttatgg ttggacgttt tccactggct gtcattcaca
     2041 tccatatcga cccttatcta gcggatgtca atgtgcatcc aactaagcaa gaggtgcgga
     2101 tttccaagga aaaagaactg atgaccctgg tttcagaagc tattgcaaat agtctcaagg
     2161 aacaaacctt gattccagat gccttggaaa atcttgccaa atcgaccgtg cgcaatcgtg
     2221 agaaggtgga tcaaactatt ctcccactca aagaaaatac gctctactat gagaaaactg
     2281 agccgtcaag acctagtcaa actgaagtag ctgattatca ggtagaattg actgatgaag
     2341 ggcaggattt gaccctgttt gccaaggaaa ccttggaccg attgaccaag ccagcaaaac
     2401 tgcattttgc agagagaaag cctgctaact acgaccagct agaccatcca gagttagatc
     2461 ttgctagcat cgataaggct tatgacaaac tggagcgaga agaagcatcc agcttcccag
     2521 agttggagtt tttcggacaa atgcacggga cttatctctt tgcccaaggg cgagatggac
     2581 tttacatcat agatcagcac gctgctcagg aacgggtcaa gtacgaggag taccgtgaaa
     2641 gcattggcaa tgttgaccag agccagcagc aactcctagt gccctatatc tttgaatttc
     2701 ctgcggatga tgccctgcgt ctcaaggaaa gaatgcctct cttagaggaa gtgggcgtct
     2761 ttctagcaga gtacggagaa aatcaattta ttctacgtga acatcctatt tggatggcag
     2821 aagaagagat tgaatcaggc atctatgaga tgtgcgacat gctccttttg accaaggaag
     2881 tttctatcaa gaaataccga gcagagttgg ctatcatgat gtcttgcaag cgatctatca
     2941 aggccaatca tcgtattgat gatcattcag ctagacaact cctctatcag ctttctcaat
     3001 gtgacaatcc ctataactgt cctcacggac gtcctgtttt ggtgcatttt accaagtcgg
     3061 atatggaaaa gatgttccga cgtattcagg aaaatcacac cagtctccgt gagttgggga
     3121 aatattaaaa gtataaaaaa gtctgggaaa aattttcaaa atcagaaaaa cgcataaaat
     3181 caggtgttca aaaaccttga ttttatgcgt tttatcatgg aaatagttac ttcatgtttt
     3241 cctaattctt ttcgaaactc tttttaaacc acgtcagttt tatcagtaat ctcaaaacag
     3301 tgttttgagc taattttgcc agttttgtct gtaacatcga agttgtgttt gaccactctg
     3361 cgactggttt cctagtttgc tctatgattt tcacagagta ttaaattgcg attttgccaa
     3421 gtttctttat tcgtctaaaa gtagagtctg ttctatgcgt ctaatgtacg aattaggttg
     3481 accatttcaa tagctccttg tgcacactca gaacccttat ttcctgcttt agtgccagct
     3541 cgttctatgg cttgttcaat tgtatctgtc gttagcacac caaacataac aggaatttcg
     3601 ctatttaaac tgatttgggc gattccctta gatacctcgc tacatacata atcataatga
     3661 cttgtattcc ctctaatgac agctcccaag cagataattg catcatattt tttacttttt
     3721 gccatttttg atgcaatcag tggtatttca aaagctcctg gaacccaggc tacctctata
     3781 tctttctcgt ttacattctc tcttttgaga ttatctagtg ctccagataa taattttgaa
     3841 gttataaatt cattaaatct cgctacaaca atacctattt taatattgtt tgctactaaa
     3901 ttaccttcat aagtgttcat ttatttttcc tccatattta aaatgtgacc cattcgattt
     3961 ttctttgttt ctaaataaaa actatcgtaa ggattggctt ctatttcgat tgatattcta
     4021 ctggaaatgg taattccata tttttctaac tgttcaacct tgtcaggatt atttgtcagt
     4081 aaatgaagtg actgaagtcc cagatcttta agcatttgtg ctccaatatg atattctctt
     4141 aaatcacctt caaagcctaa tgcaagattg gcatcaagcg tatccatgcc ttgatcttgt
     4201 aaatgatagg cttttaattt attgataagt ccaattcctc gtccctcctg tcgcaagtaa
     4261 agtaagacac ccgaaccatt ctcaacaatc attttcatag ctttatcgaa ttgctgtcca
     4321 caatcgcaac gtaaagagcc taaaacatct cctgttaaac attcggagtg gacccgacat
     4381 aatacattgg cttcatcctc tatgtttccc ataataagag caagatgatg ttccccattt
     4441 agtttatcta tatagctaat tgctttgaaa ttaccgtatc tagtaggcat attgacagtt
     4501 gaaactcgtt ctaccagctg atcatatact tttctatatt cttgtaattc tttgatggta
     4561 attagtggaa tgttgtgttt cttcgagaac tgaattaaat catctgttct catcattttg
     4621 ccatcatgat tcattatttc acaacatagg ccacactctt ttagtccagc taattttaat
     4681 aaatcaacag ttgcttctgt gtgtccattt ctttctagaa caccaccttt ttttgcaatt
     4741 aaaggaaaca tgtgtcctgg cctgcgaaaa tcagagggtg ttatatcttc agctacacac
     4801 atacgtgcgg tcagtcctct ttcctcggca gaaatacctg tggtcgtttc tttataatca
     4861 attgaaactg taaaagcagt cttatgatta tctgtattgt tttcaaccat aggtgaaagc
     4921 attaattgat tagctaaact ttcgctcata ggcatacaaa ttaatccttt ggcataagta
     4981 gccataaaat taacattttc tgttgtagct gcttgtgcag aacaaattaa gtctccttca
     5041 ttttctctat ccttgtcgtc tataacaaga acaagtcgtc ccttctgcaa tgcttctaat
     5101 gcttcttgta tttttcgata ttccattgac tgattatcct ttctgctaaa atccattttg
     5161 atataatagt tccttagata tttctgattt tggagagtta tccatcagtt tttgcacata
     5221 tttacctaag atatcatttt caagatttac tgtactcccg acttgtttac tcttaagaat
     5281 ggtttgttcc aaggtatgag ggataacaga tactgaaaag tttactttgg agactttagc
     5341 gacagtcaga ctaatgccgt caattgtaat agatcctttt tcaactatta aatctaaaat
     5401 ttctttttgt gtgttgattt gataccatac agcattatca tcttttttta ttgacgagat
     5461 ttttcctgta ccatcaatgt gtcctgtaac gacgtgaccc ccaagtcgac cgttgacaga
     5521 taaggctctt tctagattca cctcacttcc atgttttaat agagtaagag ctgttcgact
     5581 ccatgtttca ttcattacat caactgtaaa ggattgatga ttgaaatgag taactgtaag
     5641 acagatacca tttactgcta tactatcgcc taaatggata tccgttaata tttttgaggc
     5701 tttaattgat agtttacaat tacgagagtc tttctgtatt ctttcaactt ttccgatttc
     5761 ttcaattatt cctgtgaaca tggataaatc acttcacttt ctatgagata gtcatttcct
     5821 atttgagaaa atgcataagg tttcaatcta atagcgtcat ttggcaaaga aatgccttca
     5881 cctccgacag gaaacttggc actgcctcca aaaatttttg gtgcaatata tattttcagc
     5941 tcatcaacaa tttgttgttc caaagcactc caattcatta gactgccccc ttctagaact
     6001 aggctatcaa tctgcatgtt tcctagatgt tgcattaaac tcgataagtc tatatgattg
     6061 ccttttttct ttatggaaag tatttcacag ccatgatttt gatatagctt cattttattt
     6121 ttgtcttcag aggaagtggc aatgtaagtt ttaatatcat ttgctgtttt tacgatttta
     6181 gaggtaagag gagttcgtaa atgtgtatcg catatgatac ggataggatt tttcccttcc
     6241 tccaatctac atgtcagcaa aggatcgtct tgaataacag tattgactcc caccataatt
     6301 gcactaacat ggtgtcgtaa ctgatgcaca tgctttcttg cttcttcttc agtaatccat
     6361 ttggattgat ttgttttagt ggctattttt ccatccattg acattgcata tttcataaaa
     6421 acatagggta catgctgggt aatatacttt ctaaaacttt ttattaagtt aagacactca
     6481 ttttctaaaa ttccaacagt aacttgaaga ttattttcct caagtatctt tactcctttt
     6541 ccagatacaa taggattaca gtctaggctt ccaatgacta ctcttgtaat accactatcg
     6601 attatagcat ctatacaggg aggtgttttc ccgaagtgac aacagggttc aagtgttaca
     6661 taaagcgtcg ctccgacagg ggattttcta cagtttttaa gagcatttct ctcagcatgt
     6721 gggccaccaa aaaactcatg ataaccttgt ccgataatgt gattatcttt tacaataatt
     6781 gcgccaacca taggattggg attgacgtaa ccagcccctt tttgtgccag ttttattgct
     6841 aatttcatat attttgaatc gctcatctca ctacctccaa aaaaatatac cttgaatagg
     6901 ggactactca aggcatacaa aagaaaactt atgcgattaa caaaaatgct ctgaaatgac
     6961 aagtaatcat ttcagagcac gcaaaaagca caaatatact tttatcttct ttcatccaga
     7021 ctatactgtc ggctttggaa tttcaccaaa tcatgccttt cggctcgtgg gctataccac
     7081 cggtagggaa ttgcaccctg ccctgaagat agttattcaa ttacagatga ttatagtact
     7141 taattttgaa tatgtcaaca gataaataca gattgttttt gatatactgt atttgtgata
     7201 atcgattctc gctcctcgga taaagaaaat atgatatact agataaacga aataagagag
     7261 aaggaacact atgtacgcat atttaaaagg aatcattacc aaaattactg ccaaatacat
     7321 tgttcttgaa accaatggta ttggttatat cctgcatgtg gccaatcctt atgcctattc
     7381 aggtcaggtt aatcaggagg atcagattta tgtgcatcag gttgtgcgtg aggacgccca
     7441 tttgctttat ggatttcgct cagaggatga gaaaaagctc tttcttagtc tgatttcggt
     7501 ctctgggatt ggtcctgtat cagctcttgc tattatcgct gctgatgaca atgctggctt
     7561 ggttcaagcc attgaaacca agaacatcac ctacttgacc aagttcccta aaattggcaa
     7621 gaaaacagcc cagcagatgg tgctggactt ggaaggcaag gtagtagttg caggagatga
     7681 ccttcctgcc aaggtcgcag tacaagcaag tgctgaaaac caagaattgg aagaagctat
     7741 ggaagccatg ttggctctgg gctacaaggc aacagagctc aagaaaatca agaaattctt
     7801 tgaaggaacg acagatacag ctgagaacta tatcaagtcg gcccttaaaa tgttggtcaa
     7861 ataggagcag agaatgacaa aacgttgttc gtgggtcaag atgaccaacc cgctctacat
     7921 cgcctatcat gatgaggagt ggggtcagcc cctccatgat gaccaagcat tgtttgagtt
     7981 gttgtgtatg gaaacctatc aggcaggcct gtcttgggaa acggtactca acaaacgcca
     8041 agctttccga gaagcctttc atagctatca aattcactca gtcgcagaga tgactgacac
     8101 tgaattggaa gccatgctgg agaatccagc tatcattcga aatagagcca agatttttgc
     8161 tacacgcgct aacgcccaag cctttctaca gttacaggca gagtacggct cttttgatgc
     8221 ctatctttgg tcttttgttg aggggaaaac tgtcgttaac gatgttcctg attatcgcca
     8281 agccccagct aaaacaccct tatctgagaa attagccaaa gatctcaaaa aacgaggctt
     8341 caagttcaca ggcccagtcg ccgtattgtc ttttctacag gctgcagggc tagttgatga
     8401 ccacgagaat gattgtgagt ggaaaggtct taaatgatgt ctaacaaaaa taagggaatt
     8461 ctgatttttg cgattctcta tacaatcctc tttgtgtttg atggcgttaa attgctggct
     8521 tctttaatgc catctgtcat tgcaaattat cttgtttatg tagttttagc tttatatggc
     8581 tccttcttgt tcaaggatag attgatccaa caatggaagg agattagaaa gactaaaaga
     8641 aaattcttct ttggcgtctt aacaggatgg ctctttctca ttctgatgac tgttgtcttt
     8701 gaatttgtat cagagatgtt gaagcagttt gtgggattag atggacaagg tctaaatcag
     8761 tctaatattc aaagtacctt tcaagaacaa ccactactga tagctgtttt tgcttgtgtc
     8821 attggacctc tggtagaaga attatttttc cgtcaggtct tattgcatta cttgcaggaa
     8881 cggttgccag gtttactaag cattattctg gtaggacttg tttttgctct gactcatatg
     8941 cacagtttgg ctctatcaga gtggattggt gcagttggtt acttaggtgg aggccttgcc
     9001 ttttctatta tttatgtgaa agaaaaagag aatatctact atcccctact tgttcacatg
     9061 ttaagcaaca gcctctcctt aatcatttta gctatcagta tagtaaaatg aaatgagaac
     9121 aggacaaatc gatttctaac aatgttttag aagtagaggt gtactattct agtttcaata
     9181 tactgtaata tgtgatgaaa atgccagtaa tgataccgag aaaaaagctg agaaactttt
     9241 cccagcttta tttgttatag tcaaagagaa tgacttgttc ctgtgcatct acatgagcat
     9301 ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc gacattcaga ttatagacaa
     9361 tcgggatatt gctgtcaatg atatccaata gtgcctcttt atagtcgtca tggaaagttt
     9421 catccatagg ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtgtccttta
     9481 aagttagcaa catttttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca
     9541 agaggatttt cccttcccag tctgacaagt cagggaaaag tttgtatttt tggcagagtt
     9601 ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta gagggattcg aggcaaccac
     9661 cgaggatttt cccctcgaac tgagcacttc cttgcaacaa gtcaaaacct gtatttgtat
     9721 gactgacacg aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa
     9781 cgtcactagg gcggatttct gaaattcttc ccgtcttaat caattcttta aagtagtgaa
     9841 ggctataggc tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat
     9901 aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc
     9961 caagaaaaat tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta
    10021 gcaagcgata ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag
    10081 aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc
    10141 cttttaacga atgggacaaa aagatgggat tgagtcccag atccttgaga cgttggatac
    10201 ccaagtccac ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa
    10261 taccaatagt agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca
    10321 aaatataaga gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc
    10381 tcttcaaacc acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc
    10441 tagcttccta gtttgctctt tgattttcat tgaatataac tcaaaaaagt aagtgaaaaa
    10501 gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc
    10561 acttgcacta cggatattca agcgtttctt gagatagaag cgaagggcta ggagggctgc
    10621 tccaataata gctagtggca atggatccag tactgggtta aggctagctg gtaggaagct
    10681 tgttgcaaag aagacaagca accaaaggaa catagaagct aggataacta gtacagattt
    10741 ccagaaaggt ggacgttgac tgcgatccat atctgatcca tagtattggt aaacaaagta
    10801 gtacatcaag tagaaggcaa atccaccaac cagtccaact aatagaagag taatcaatcc
    10861 atagccgaaa gcttggtctg ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag
    10921 gctagtgatg aaaagagctg agtccataat catcagtttt gggtcatcat tttcttttgg
    10981 atgctctttt tcgtactgct ctttgacagt gaagctatga gcccaatgag ttggtgcgcc
    11041 gtatagggaa cgggcagttg tacctttaga ttgctcctca aggatttggg gaatgacttc
    11101 ctcaaaaata gtctggattt cagcgtctgt tttcccatct ttgatgaatt gttgggtagc
    11161 aatgtggaca aactcttggt ttttcttagt taatttttgt agatcaattt gagacatagg
    11221 aactcctctt agaaccattt tttatggatg agatagagag tgagcgagac actcatagca
    11281 aaggcgataa agacgattaa ccagaaggca tttggctctc cgtttagggg gatttcatta
    11341 tccttaaagt tcatcccgta ggcagaaaag accatggttg ggatggacat gacgatggtc
    11401 acaagggcca aggttttcat gatgttgttc tggttgttag aaatgataga ggcaaaggtc
    11461 tctgtcatag aatgcaagac gtttccataa atatctgcca tctcgatggc ctgttgggtt
    11521 tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt atttcttgat attgctggtt
    11581 gaactggtca atttcttaat cacgcgctca tttgttttga gggaggcctt gaaatagacg
    11641 atagtttttt ccaattccat gagctcaatc aattcttcat tacgagttga ttgatgcagt
    11701 tgactttcga tttgttcact cttgcggtcg attgaacgaa gggctgttag gtaaagctct
    11761 gcattgcgat aaagaatttg aaagataaaa cgtgaacgca tgaaggtata gaaattacgc
    11821 aatcgacggt tgataaagac atcaaggaca ggtagtggtt ccaaacacgt agtgataatg
    11881 gtttcctcag tgatgataat accaagcggg atggttacgt agtaggtgcg gttatttctt
    11941 tcctccgtga ccggcacgtc tacgataatc agggtatact cgtcttcaat ggtaatacga
    12001 gacatttctt ccgcatcgag cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg
    12061 gcgatttcga gtgattcatt ttgagtcgga ttgacgagat tgatccaagt acccggttca
    12121 agcgtatcga tctctttaaa ttcagttgtt gtagagagaa aaacttgttt catatccctt
    12181 atcctttctc atttttcaga ttttttcaca ctgtactatt atactacaaa atcggccttt
    12241 tgggtaatag aatctcactt tttttggtat aatggtaagc aataatggac tagaaagaac
    12301 aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc cataatttaa aaaatattga
    12361 tgtggagatt ccgcgagaca agttggttgt cgtgactggc ttgtcaggtt cagggaagtc
    12421 cagtctggct tttgatactc tctatgcgga gggacaacgt cgctatgtag agagtttgtc
    12481 cgcctacgct cgtcagttct tgggaaatat ggaaaaacca gatgtagatg ccattgatgg
    12541 tctcagccca gctatttcca tcgaccagaa aacgactagt aaaaatcctc gctcgacggt
    12601 gggaacgacg actgaaatca atgactatct gcgtctcctc tacgcacgtg tggggacgcc
    12661 ttactgtatc aacggacatg gagctatcaa tgcttcttct gtggagcaaa tcgttgataa
    12721 ggttttggag ttacctgaac gccagcgctt gcagatcttg gctcctgtca tccgcaagaa
    12781 aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa gacgggtatg ttcgtgtccg
    12841 tgtggatggg gaagtctatg atgtgaccga agtgccagag ttgtctaaga gcaagcaaca
    12901 caatatcgat gtcgtggttg accgtattgt tatcaaggag ggcattcgta gtcgtctctt
    12961 tgattccatt gaggctgccc ttcgtattgc agaaggttat gtcattatcg acaccatgga
    13021 cgactcggag ttgctcttct ctgagcatta tgcctgtcca gtttgtggat ttactgtccc
    13081 agagttagaa cctcgtctct tctctttcaa tgctcccttt ggctcttgta gtgagtgtga
    13141 cggcttgggg attaagctgg aggtggatac tgatttggta gtgccagatg ccagcaaaac
    13201 cttacatgag ggagcgctgg caccttggaa tcctatctca tccaactact atccaaacat
    13261 gttagagcag gccatgaaag tctttggagt ggctatggat aagccttttg aggacctgtc
    13321 agaagaagat aagaacttga ttctctacgg ctcagatggt aaggaattcc atttccatta
    13381 tgaaaatgaa tttggtggtg tgcgcgatat cgacattccg tttgagggag ttatcaataa
    13441 tatcaaacgt cgttaccatg aaaccaatag cgattacact cgcactcaga tgcgtctcta
    13501 catgaatgag ctgacctgcg gaacctgtca aggctatcgt ctcaatgacc aggccttgtc
    13561 tgtccgtgtg ggcggccagc aagggccaca tattggagaa atctcagacc tgtctatcgc
    13621 tgaccacttg gacttggtga gccagttaac tttgtctgaa aatgaagcca tcattgctcg
    13681 tcccattctc aaggaaatca aggatcgttt gaccttcctt aataatgtgg gtcttaacta
    13741 tctaaccctg tcacgttcag caggaaccct ttcaggtggg gaaagtcagc gcattcgttt
    13801 ggcaacccag attggttcca acctatcagg tgtcctctat atcctagacg agccgtcaat
    13861 cggtcttcac cagagggaca atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt
    13921 gggcaatact cttatcgtgg tggaacacga cgaagatacc atgcgtgaag ctgattatct
    13981 gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag attgttgcag caggtacacc
    14041 taagcaagtg gctcgcaaca gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt
    14101 catcccagta ccagaagagc gccgtgtcgg aaatggtcgt tttattgaag tgacaggagc
    14161 gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt
    14221 gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac agcattctca aaaaagccat
    14281 tgcccagaag ctcaaccgta attcagacaa acctggtaag tttaagacta ttacagggat
    14341 tgagcatgtc gaccgtttga ttgatattaa ccagagccct atcggacgga cgccgaggtc
    14401 taacccagct acctatacag gagtttttga cgatatacgt gacctttttg ctcagacaaa
    14461 tgaagccaag attcgaggct acaagaaggg gcgcttcagt ttcaacgtca agggaggtcg
    14521 ctgtgaagct tgctcaggtg acgggattat caagattgag atgcacttct tgccagatgt
    14581 ttatgtggct tgtgaagttt gccacggaac ccgctataac agtgaaaccc tagaagttca
    14641 ctacaaggaa aagaatattt cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt
    14701 tttccaacac attccgaaaa ttcaacgcaa actccagacc atcaaggatg taggtctagg
    14761 ctatgtgacc ttgggacagc cagctaccac cctttctggg ggagaagccc aacgtatgaa
    14821 gttagctagc gaactccaca aacgctcgac aggaaaatct ttctacattc tggatgagcc
    14881 gacgacaggg cttcatacag aggacattgc tcgcctgctc aaggttttag ctcgctttgt
    14941 agacgccggc aatacagtcc tcgtcatcga gcacaatctg gatgttatca agacggcaga
    15001 ccatatcatt gacttgggac ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg
    15061 aactccagaa gaagtagctg ccaacgaagc cagctataca ggacactatt tgaaaggaaa
    15121 gttacatcat gaataaacgc gtacaagcat ttctagctaa aatgcaagaa aaagaactag
    15181 atggtatcat catcaacaat cttaaaaacg tctattattt gactggtttt tggggctcaa
    15241 acggaacagt ctttatcagc cgtgaccgtc aggtcttagt gacagactct cgctatatca
    15301 tcgcagctaa gcaagaaacc agtggttttg agattgtggc tgatcgtgat gaattggctg
    15361 tcattgcagg aattgttaag gacatgaact tgactcgtat cggttttgaa gatgagattt
    15421 cagtgtctta ttaccaccgt atgcaggcag cttttgcagg tttgaacttg cttccacaaa
    15481 ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc agagattgca gcgattcgca
    15541 aggcttgttc tatctcagac caagctttcc gcgatgcgct tgactttatc aaaccaggaa
    15601 aaactgaaat tgagattgcc aacttccttg atttccgcat gcgtgagttg ggagcatctg
    15661 gcttatcttt tgatacgatc ctagctagcg gtatcaattc ttctaaaccc catgcccatc
    15721 caatgcacaa accagtggag ttgggagaag ccatcaccat ggacttcggc tgtctctatg
    15781 accactatgt cagtgatatg acccggacta tctatctagg gcatgttagc gatgagcagg
    15841 cagagattta caatacggtt ctaaaagcta accaagcctt gattgaccaa gctaaggcag
    15901 gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat tatcattgag gcaggttatg
    15961 gtgactactt tactcacggc attggccacg gtattggtct ggatatccat gaggaaccct
    16021 actttagtca gacttctaca gaaactatta agacaggtat ggccttgacc gatgaaccag
    16081 gtatctatat cgaaggcaaa tatggcgttc gtatcgagga tgatatcctg attacagaga
    16141 caggttgtga attattgacc ctagctccaa aagagttgat agtcatttag ttgtttgtca
    16201 agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat taaaaatagg tcgcaagtcg
    16261 gatgtttttt atggtataat agactaaact gatagtaaca tgtagcgaaa ggggtaggta
    16321 catgattaaa atttatacag tctcaagttg tactagctgt aaaaaagcaa aaacctggct
    16381 caatgcccac cagttaagtt ataaagaaca aaaccttggt aaagaaggaa ttacgagaga
    16441 agaattactg gatattctaa ccaaaacaga taacggaata gccagcatcg tttcgtctaa
    16501 aaatcgctat gccaaagccc ttggagtgga tattgaagat ttgagtgtca atgaagttct
    16561 caatctgatt atggaaacac cgagaatttt aaagagccca atccttgtag atgaaaaacg
    16621 cctgcaagtt ggctacaagg aagacgatat tcgtgccttc ctaccacgat ctgtccgtaa
    16681 tgtagaaaat gcagaagcac gtttgcgtgc agctctataa acatcaaggc tgggagcact
    16741 tcccagtctt attctatttt aatttcaaaa agaaagaaga aagaaatgaa aaaaatagtt
    16801 cttgttagtc tagctttcct ttttgtcctg gttggttgcg gacagaaaaa agaaactgga
    16861 ccagctacaa aaacagaaaa agatacgctt cagtcggcat tgccagttat tgaaaatgct
    16921 gagaagaata cagttgtaac taagactttg gtcttgccca agtcagatga tggtagccag
    16981 cagacacaaa caattactta caaagacaag acttttttga gtctagctat ccaacaaaaa
    17041 cgtccagtct ctgatgagtt gaagacttat attgaccaac atggagtgga ggaaactcaa
    17101 aaagctcttc ttgaagcgga ggagaaggat aagtctatca ttgaagctcg taaattggca
    17161 ggtttcaaac ttgaaacaaa actattgagc gcaacggaac ttcaaacaac gactagtttt
    17221 gattttcaag ttctggatgt caagaaggct tcccagttgg aacatctgaa gaatattggt
    17281 ttggaaaatc ttttgaaaaa tgaaccaagc aaatatattt cagatagatt ggcaaatggc
    17341 gcgacagaac aatagaaaat ccaaataaat agactgcctg aattgtagaa ggtaaggaat
    17401 tatgctataa tggtactatt ctaaggaaag agggtgttag aatgggattt actgaagaaa
    17461 cagtacgttt taaattggac gattccaata aaaaagaaat tagcgaaact ttgacagatg
    17521 tttatgcttc gttgaacgat aagggttaca acccaattaa ccaaatcgta ggttacgtat
    17581 tgagtggaga ccctgcctac gttcctcgtt ataataatgc acgaaatcaa atccgtaagt
    17641 atgagcgtga tgaaatcgtt gaggaattgg ttcgctacta cctcaaagga caaggagtcg
    17701 atctataacc tatgagaatt atgggattgg acgtcggttc aaaaacggta ggggtggcga
    17761 ttagcgatcc gcttggtttt acagctcaag ggcttgaaat catccagata aatgaagaac
    17821 aaggccaatt tggttttgac cgcgttaagg aattggttga tacttacaag gtggaacgat
    17881 ttgtagtggg cttgcctaaa aacatgaaca atacaagtgg accgcgcgta gaagctagtc
    17941 aagcctacgg agcaaagcta gaagagtttt ttggtttacc agtagactat caggatgaac
    18001 gcttgacaac agtggctgct gagcgcatgt tgattgaaca agcagatatc agtcgcaata
    18061 agcgcaagaa agtcattgat aagttagcag ctcagctgat tttacaaaat tatttagata
    18121 gaaaatttta atataaagga gaggctatgt cacacgatca taaccacgac cacgaagaac
    18181 gtgaactaat cacactagta gatgagcaag gaaatgaaac cttgtttgaa atccttttga
    18241 caattgatgg aaaagaagaa tttggtaaaa actatgttct tctagtacca gttaacgcag
    18301 aagaagacga agacggacaa gttgaaatcc aagcttactc attcattgaa aatgaagatg
    18361 gaacagaagg cgaattgcaa ccaatcccag aagactcaga agacgaatgg aacatgattg
    18421 aagaagtctt caacagcttt atggaggagt aaaaacgtcc gggggacgtt tttagccctg
    18481 cgctagaaat tagaaacgca ggtagtctgg gagactgtat cagcccaact ccagaaatgg
    18541 ggaagagttg gaacgtccag tgaacatttt taccccaact cttagaaatt gagaagagtt
    18601 ggaacatcta gtggatgttt ttagcccata ttcacattca tagtagctag ttattagcta
    18661 accaggtaag aggtcgggac gaaaatcctg gccttgtttt tattagtaac catactttaa
    18721 tgcgataatt gattggactt ttgtcaagga gatgtgtatg tttgaagtag aagaatggct
    18781 ccatagtcgg attggtttga attttcgatc aggtttgggc cgaatgcagc aagcggtgga
    18841 tttgttagga aatcctgagc agtcttaccc tattatccac gtaacaggga ctaatgggaa
    18901 aggatctacc attgctttta tgagggaatt atttatgggg catggcaaaa aagttgcgac
    18961 ctttacctcc cctcatatcg tatccatcaa tgaccgaatc tgcattaatg ggcaacctat
    19021 agcagacgca gactttatcc gtttggctga tcaggtaaag gagatggaga aaacgcttct
    19081 gcaaactcct gaccagttgt ccttttttga attgctgacc ttggttgctt ttctttattt
    19141 tagggagcag gaggtggatt tggttttatt agaagtggga attggtggct tacttgacac
    19201 gaccaatgtg gtaactggag agcttgctgt catcacctcc attgggcttg accatcaaga
    19261 aaccttgggt gatagtctag aagcaattgc agagcagaaa gctggtattt tcaaggctgg
    19321 taaaaaggca gtgattgcga aattgcctcc agaagctaga cttgtctgtc agaaaaaagc
    19381 cgaatcttta gctgttgacc tttatcaggc aggtcaagat ttttcagtgc tgaatggtga
    19441 tttttcaagc tctttactaa atctttcaca gctgaacata ggcttagaag gagcctatca
    19501 gcaggagaat gcggccttgg cgttgcaaac ttttcttctt tttatgggag aaagaaagga
    19561 agctattgat gaacaggctg taagaaaggc cttggaacag acccattggg ctggtcgctt
    19621 ggagcgtatt cgcccacaga tttacttgga tggtgctcat aacctccctg ccttgactcg
    19681 cttggttgag tttatcaaag aaaaagagca ggaaggctat cgacctcaaa tcctctttgg
    19741 atccttgaaa cgtaaggatt atcaagggat gttgggttat ctgactgaaa atttacctca
    19801 agtggaactc aaaatgaccg gctttgacta tcaagggtct ttggacgaga cagatgtaac
    19861 aggttaccat gtaattccct cttaccgaga atttatcagc agtttcgaag aaagggcaga
    19921 cgctcaagac ttgctgttcg ttacagggtc tctctatttt atctcagaag tacggggcta
    19981 cctgctggac cgtgagcaga taaattgacc cccttttttg aacttgttat actaggggaa
    20041 ttgctggtta gagaaaattt ctctaaattg gtagcagaaa ggaaattcat catgaaatta
    20101 aaaagattca cactttctct tgcttctcta gcaagtttta gtctcttagt agcttgttca
    20161 caaagagctc aacaggttca acagcctgtt gctcagcagg tccaacagcc tgctcaacag
    20221 aataccaata ctgcaaatgc aggaggtaac caaaatcaag cggctccagt acaaaaccaa
    20281 cctgttgctc aaccgaccga tattgatggg acttatactg gtcaggatga cggagaccgt
    20341 atcactttag tggtaactgg aacgactggt acatggactg agctcgaatc tgacggggat
    20401 cagaaagtca aacaggttac atttgattca gcaaatcaac gcatgattat tggcgatgat
    20461 gtcaaaattt acactgtaaa cggtaatcaa atcgtcgtag atgatatgga tagagaccca
    20521 tcggaccaaa tcgttttaac taaataagac tatgcaagta gaaagggctg gatttttcag
    20581 cctttttact tttacctaga aaataatcat aaatacttgc cttctaccga atacctgcgt
    20641 tatactagta tcaattactt gtttttagca ttcaaactat caaggagggg atatgaaata
    20701 taggaaattt caattattga tgtccaagta tggctttagt ctttcgatta tgctacttga
    20761 actttgtctt gtttttggtc tctttcttta tttaggacgc atggctccca ttttatggat
    20821 tactgtcctc attctactga gtatcatcac aatcatttcg atagtcaacc gtaatacgac
    20881 tcctgagaat aaggtaacct ggttgttagt agcctttgtg ccagtatttg gtcccttgct
    20941 ctatctgatg tttggtgaaa ggcgattgtc caaaaaagaa atcaaacaac tgaagaagct
    21001 aggctctatg catttccaag aagcaaatag ccagctacta aaagagaaat taaaagaaag
    21061 tgacaaggca gcttatggag tcatcaagtc cttattgagt atggatacca atgctgacat
    21121 ctatgatcaa actgcctcta cattttttcc taacggagaa gctatgtgga aaaagatggt
    21181 agaagatctt aaaaaggctg agaaatttat tttcttggaa tattacatta tagaagaagg
    21241 tttgatgtgg aatcgcatac tagatatact agagcaaaag gtagctcagg gtgtagaggt
    21301 taagatgctc tatgatgata tcggctgtat ggctacttta acaggagatt atgcacatcg
    21361 acttcgtcag ctgggcatcg aggcccataa attcaataaa gttattcctc gtttgacagt
    21421 ggcttataat aacagagatc atagaaaaat attgattgtt gatggtcaga tagcctatac
    21481 tggtggggtc aatctggcag atgagtacat taaccacgtc gagagatttg gttattggaa
    21541 ggatagtgga attcgcttag acggactagc agtaaaagcc ctgacacgct tatttttgac
    21601 cacttggtac attaatcgag gagaaattag tgattttgat caatatcatt tagaaaatca
    21661 ttctatcccg agtgacggtt taaccattcc atacggaagt ggacccaagc caatttttcg
    21721 agcgcaggta gggaaaaaag tttatcagag tttaatcaat caagcaacag aatcggtcta
    21781 tattacgaca ccttatttga ttatagatta tgatttaaca gagacaatca aaaatgcagc
    21841 tatgagaggg gtcgatgttc gaattatcac cccttacata ccagataaga agttcattca
    21901 gttagtcacg agaggagctt atcccgacct tctttctgct ggtgttcgga tttatgagta
    21961 tagtccaggt tttattcata gtaagcagat gttggtagac gaagattttg cggtggtggg
    22021 gacaatcaat ctcgactacc ggagcttggt acaccattat gaaaatgcag tcttactcta
    22081 taaaactcct tctataaggg aaatcgcccg agattttcga aatatatttg cagattctca
    22141 ggaagtctat cctcattcta tcaaaacgag ctggtatcaa aagcttgtaa aagaaatcgc
    22201 ccagctattc gcccctatct tataagaaat ctagaactta ggatacaaac cagccctatt
    22261 tttcttgtct tttactaata gaaagaaaga ggaggggaat tcatgctaac taaggaagaa
    22321 gtgaatgata tgattgagtt caaacagaca catttacacc gctttcggga aattgaaacc
    22381 tttgtgaaac tatgcaaaaa atcactcaaa cagccatcgc aagctgacaa tcctaggact
    22441 ttttgatata ctaagacaga taaattgaac aggagaaacg atatgagtgt gtatggtaga
    22501 gtagaagaag ttcataagga gaatcgtgaa cctctagaat accaaatcga acaagaatcg
    22561 catcatcgtg aatcaagtcg tcttcctttg gtgaaaattt tactatggag tacgcttgta
    22621 acggggataa ctctaggagt accgctatta ctcgacttaa tgagtgcaca agaagtgcag
    22681 gatttttatg caggttgggc gcttcatcag acagggaaga tttacagcga ctattatgga
    22741 agtcaaggtt tgctttatta tttgctgact tacgtgagtc agggcggatt tttctttgcc
    22801 atctttgagt ggttagcctt ggtagcagga ggatttttcc tttttagatc agcggacacc
    22861 ttgacagagc aaggagacca agctggacat ctggtgacta ttttttacat gctagttaca
    22921 ggtcttgctt ttggtggagg ctatgcgact cttttagcgc ttcctttctt attcgcagcc
    22981 tttagtttag ttgcggctta cctaagcaat ccaagccatg ataagggatt tgtacggatt
    23041 gggctagctt tggcaggcgg atttttcttt gctcccttat catcgctcct gtttattgct
    23101 gtagtgggtt taggcttgtt ggtctttaac cttgggcata gacgctttgc gcatgggttt
    23161 tatcagtttc ttgcagtggc tttaggtttt tcacttgtct tttatccaac tgcctactat
    23221 agtgctgcaa caggaagttt tggggatgcg attagtggta ttcgttatcc tattgacagt
    23281 attcgctttg attttacttc taaaatttta gagaatatgt ttttttatgg cttgttgtcc
    23341 cttggtttgg gatttgtggt ttgtatcttt ttaggtctct ttcaatccaa accctttaaa
    23401 ctatacgtca tttcggttcc tgcaagtctt gttgtaattt taggtttgat tttacttttc
    23461 ttttcacaag agcctctgca cgcttcttat ttgatggtcg tcttccctgt tttcctactt
    23521 ttattggtaa ccaatattaa gagtcaacag agggggcgta gtgctagaag aagccgaaga
    23581 gaaacgccag ttagcctatg gagtcgtttc ttcaaaggaa atctatatct gctagttttt
    23641 gggtttgtct atcttttgtc tgttcctttt ttgatgaagt ttgtccttta tccagtacct
    23701 tatcaagaac gtaatcgtct tgctgatttg gtaaaagagg agacaaatac ggaagatgct
    23761 atctatgcat gggatgatac tgcgactctt tatcgtaaga gtgagcgctt gtcgccatcg
    23821 gcgattttgt ccccgttgca ctatacagca actgaggaaa atcgtaataa gttacttaat
    23881 gacttgaaag aaaaacaacc taaggtgatt gtggtaaatg acaaggtggt agtctggtct
    23941 gaagtggaaa cacttttaaa agaaaattac caacaagtaa agactgatta ctcagagttt
    24001 aaagtctata aaattaaata accaaatcaa tatcttgtgt atttttagaa attttaggat
    24061 ttttaacaca agatattgat ttttcttttt agagtggtat aatacttttt agaaagaaca
    24121 ttttagaaaa gagcatgcgt atgattgcac tagaagaaaa aattacaatt ttgccaactc
    24181 tcttcgtcga gaaacgagat gggagacgtg ttgtatttga tgtggacaag attgacaagg
    24241 ctctccacaa ggcggctgac aaggttatgg atgtgacacc cctggttgaa aaacgcctca
    24301 atgatctgac tgagcgaatt attacagaaa ttcatagtcg ctttccacag ggaattaaga
    24361 tttacgaaat tcaaaatatc gtagaacatg aactccttga agccaaagaa tatgcgctgg
    24421 ctgaggagta tattacttat cggacacaga gggattttga gcgctcaaaa gcgacggata
    24481 tcaactttag tattcataaa cttctcaaca aagaccagac agttgtcaat gaaaatgcta
    24541 ataaagacag tgatgtcttt aacactcagc gtgatttgac agcagggatt gttgggaaat
    24601 caatcggact gcaaatgctt cctaagcacg tagccaatgc ccaccaaaag ggggatatcc
    24661 actatcacga tttggactac agtccctata cccctatgac caactgctgt ttgattgatt
    24721 ttaagggtat gttggaaaat ggttttaaga ttggaaatgc agaggtagag agtcccaagt
    24781 ctatccagac tgcgacagca cagatttctc aaatcattgc caacgttgct tctagccagt
    24841 acggtggctg ttcagctgac cgtatcgatg aaattttggc gccttatgca gagaagaact
    24901 atcaaaaaca tctcaaagat gcagaagagt gggtattgcc tgaaaaacgg gaagattacg
    24961 cttggaagaa aacgcaaaag gacatctacg atgccatgca atctcttgag tatgaaatca
    25021 atactctctt cacttcaaat ggacaaacac cttttacttc gttaggtttt ggtctgggaa
    25081 ccagtcgttt tgaacgagaa attcaaaaag ctattttaaa cattcgcatc aagggtcttg
    25141 gttcagaaca ccgtacggct atctttccta aacttatttt cactctgaaa agaggcctta
    25201 atttagagga aggaactccc aactacgaca tcaagcagtt ggctcttgag tgtgcaacca
    25261 aacggatgta tccagatgtt ttatcttacg ataagattgt tgacttgaca ggatccttca
    25321 aggtgcctat gggttgccgt tctttcctcc aaggatggaa ggatgaaaat ggtgtagaag
    25381 tcaattcagg tcgcatgaat ctgggtgttg tgacggttaa tctgcctcgt attgctcttg
    25441 agtctgaagg tgatatgaat aagttctggg aaatcttcaa cgagcgcatg aatatcgcag
    25501 aagatgctct tgtttaccgt gtcgaacgca ctaaagaggc gacaccagcg aatgctccta
    25561 tcctttatca gtacggtgct tttggccatc atctaggtaa agaagaaagt gttgaccagc
    25621 tctttaagaa tcgtcgtgcg accgtttcgc tgggctatat cggcttgtat gaagtagcga
    25681 cagttttctt tggtaacagc tgggaaagta atccagatgc taaggaattc acgctagaca
    25741 tcattcacga tatgaaacgc cgtgtagaag agtggtcaga ccaatatggc taccatttct
    25801 ctatctactc aacaccatcc gaaagtctga cagaccgttt ctgccgacta gatatagaca
    25861 agtttggctc tattcctgat atcacagaca aggaatacta caccaactct ttccactacg
    25921 atgttcgtaa aaatccaaca ccgtttgaaa aattggactt tgagaaagtc tatccagaag
    25981 caggtgcgtc aggtggtttc atccattatt gtgagtatcc agtccttcag caaaatccaa
    26041 aggccttgga agctgtctgg gattatgctt atgaccgtgt aggctatcta ggcaccaata
    26101 ctccgattga ccgttgctac aagtgtgact ttgaagggga ttttgaacca actgagagag
    26161 ggtttgcttg tccaaactgt ggcaatagcg accctaaaac agtagatgtg gtgaagcgaa
    26221 cttgtggcta cctaggtaat cctcaagcaa gaccgatggt caacgggcgt cacaaggaaa
    26281 tcgctgcgcg tgtcaaacat atgaatggtt caacgattaa aatagctggg catcaagtaa
    26341 caaattagaa agaaatgaaa tgggaaaata tcaactagac gataaggggc gcgcacaagt
    26401 gacccgttat cacgagaaac actctaaagg tggagctggt aagaaagaac gcttgcttag
    26461 cttcagagaa caatttttaa acaagaacaa gaaaaaataa aagtgagagc cagctctcgc
    26521 ttttctcata gtgggaggta aggatggaat tacgcagacc aagattagcg gataagaaag
    26581 ctgttttaga tatgatgaca gagtttgaaa aatttcagtc gcctcacgac ggcggtttct
    26641 gggatacaga gaactttgtg tatgaagact ggttagaaag caatcaggaa caggaaatgg
    26701 gaattaatct gcctgaagga tgggttcctg caattcagtt agtggctttt tctgagaaag
    26761 gtcaagcagt tggatttctt aatctccggt tgcgcctcag taactttcta ctagaagaag
    26821 gtgggcacat tggctactcc atccgtccat ctgaaagagg caagggttat gcaaaagaga
    26881 ctctccgtca gggcttgcaa gttgctaagg aaaagaacat caagaaagct ctggtgacct
    26941 gtagcgtgaa taatcctgct agcagagcag tcattctagc aaatggtgga atatttgagg
    27001 atgctcgcaa tggagtcgag cgttattgga tagaggtagc gaatgaataa tccaaaacca
    27061 caagaatgga aaagcgagga acttagtcaa ggtcgtatca ttgactacaa ggcctttaac
    27121 tttgttgatg gcgaaggcgt gcgtaactct ctctatgtag caggctgtat gtttcactgc
    27181 gagggatgtt ataatgttgc gacttggtct tttaatgctg gcattcccta tacagcagaa
    27241 ttagaagagc agatcatggc agatcttggt cagccctatg ttcaaggttt gactttgttg
    27301 ggaggggagc cttttctcaa tactggcatt ctcttgccac ttgttaagcg gattcggaaa
    27361 gaattgtcag acaaggacat ctggtcctgg accggctaca cttgggaaga aatgatgttg
    27421 gaaactccag ataaactgga actcttgtca ctgattgata ttcttgtcga tggaagatat
    27481 gatcgaacta agagaaatct tatgctccag tttcgaggtt cgtctaacca acgaattatc
    27541 gatgtgcaaa aatcgctcaa aagtgggcaa gtagtgattt gggacaagct caatgacgga
    27601 aaagaaagct atgaacaggt gaagagagaa tgaagaaaaa aggcttagta gaccaactag
    27661 tctcagagat cgagacgggg aaagtcagga cactgggaat atacggtcat ggagcttcag
    27721 gtaaatcaac ctttgcacag gaattgtccc aagctttaga ttctactaca gtaaatttgc
    27781 tagaaacaga tccctatatc acctccggac gctatttggt agtacccaag gacgcgccga
    27841 atcaaaaggt gacagccagt ctgccagtgg cgtatgaact ggagagtttg cagagagata
    27901 tctttgcctt gcaggcgggt atggatgtct tgacaattga agaaccttgg aaggctagtg
    27961 aagtcttgtc tggagccaaa ccaattttga ttgtcgaagg gatgtctgtt ggttttctac
    28021 ccaaggaact ctttgaaaaa accatctgtt tctacacgga tgaggagacc gaattaaagc
    28081 gacgccttgc tagagatacg actgtgagaa atcgcgatgc atcctttata ttggctagcc
    28141 atcagatgag acgggagcag tatctgcgat actataaaga aactgagtct aaggcggata
    28201 tcttagtgga ccaatcagaa gataaatttg atgtcaagag gacttaactt atgtatagaa
    28261 gaaaatccct aattttagaa agaaaaagta ggaaaacagt ttcatctcaa aaaaacgaaa
    28321 aaacctaaca aatcccttgc aatcgcaggg gatttgtgtt attctattat ggtgctgtaa
    28381 attacagcct tagttttgat gcaagaggtt gcgacacgct cggttgcatt gccacgcaac
    28441 gccgcgtcgg ttttcttgtg gagctagcct attatcttaa atagacgaaa aggagaaaaa
    28501 gatggcaaac aaaaaaatcc gtatccgttt gaaagcttac gaacaccgta cgcttgacac
    28561 agcggctgca aaaatcgtag aatcagctac tcgtacaggt gcacaagttg cgggtccaat
    28621 cccacttcca actgaacgta gcctctacac aatcattcgt gcgactcaca aatacaaaga
    28681 ctctcgcgaa caatttgaaa tgcgtacaca caaacgtttg atcgatatcg ttaacccaac
    28741 tcaaaaaaca gttgatgcct tgatgaaatt ggatcttcca agtggtgtaa acgtagaaat
    28801 caaactttaa tctaaaatat aaaagagcag aggctggtgt ttcaatctaa ttgaacacgg
    28861 gctaaactcg gtgtgaaaaa gataaacttc ctcgcgtctg ctagacactg cgttagtttc
    28921 ctattttcac tttgagtttg acgccctttg tatcttagac ttgagcataa aaaacgctcg
    28981 ttaaaaactt tttgaataaa aaatatagaa aaggaactat tttctcatga caaaaggaat
    29041 cttagggaaa aaagtgggaa tgactcaaat cttcactgaa gctggcgaat tgatccctgt
    29101 aacagttatt gaagcaactc caaacgttgt tcttcaagtt aaaactgttg aaacagacgg
    29161 atacaacgct atccaagttg gtttcgatga caaacgcgaa gtattgagca acaaacctgc
    29221 taaaggacat gtagcgaaag ctaacacggc tcctaagcgc ttcattcgtg aattcaaaaa
    29281 cgttgaaggc ttggaagttg gtgctgaaat tacagttgaa acattcgcag ctggagacgt
    29341 tgttgacgta actggtactt ctaaaggtaa aggtttccaa ggtgttatca aacgccacgg
    29401 acaatcacgt ggaccaatgg ctcacggttc tcgttaccac cgtcgtccag gttctatggg
    29461 acctgttgca cctaaccgcg tattcaaagg taaaaacctt gcagggcgta tgggtggcga
    29521 ccgcgtaaca attcaaaacc ttgaagttgt acaagttgtt ccagaaaaga acgttatcct
    29581 tatcaaaggt aacgtaccag gtgctaagaa atctcttatc actatcaaat cagcagttaa
    29641 agctggtaaa taataaagaa aggggaaatc agtcacaatg gcaaacgtaa cattatttga
    29701 ccaaactggt aaagaagctg gccaagttgt tcttagcgat gcagtatttg gtatcgaacc
    29761 aaatgaatca gttgtgtttg atgtaatcat cagccaacgc gcaagccttc gtcaaggaac
    29821 acacgctgtt aaaaaccgct ctgcagtatc aggtggtgga cgcaaaccat ggcgtcaaaa
    29881 aggaactgga cgtgctcgtc aaggttctat ccgctcacca caatggcgtg gtggtggtgt
    29941 tgtcttcgga ccgactccac gttcatacgg ctacaaactt ccacaaaaag ttcgtcgcct
    30001 agctcttaaa tcagtttact ctgaaaaagt tgctgaaaac aaattcgtag ctgtagacgc
    30061 tctttcattt acagctccaa aaactgctga atttgcaaaa gttcttgcag cattgagcat
    30121 cgattctaaa gttcttgtta tccttgaaga aggaaatgaa ttcgcagctc tttcagctcg
    30181 taaccttcca aacgtgaaag ttgcaactgc tacaactgca agtgttcttg acatcgcaaa
    30241 tagcgacaaa cttcttgtca cacaagcagc tatctctaaa atcgaggagg ttcttgcata
    30301 atgaatttgt atgatgttat caaaaaacct gtcatcactg aaagctcaat ggctcaactt
    30361 gaagcaggaa aatatgtatt tgaagttgac actcgtgcac acaaactttt gatcaagcaa
    30421 gctgttgaag ctgctttcga aggtgttaaa gttgccaatg ttaacacaat caacgtaaaa
    30481 ccaaaagcta aacgtgttgg acgttacact ggttttacta acaaaactaa aaaagctatc
    30541 atcacactta cagctgattc taaagcaatc gagttgtttg ctgctgaagc tgaataatct
    30601 aaggaggaaa tatcgtggga attcgtgttt ataaaccaac aacaaacggt cgccgtaata
    30661 tgacttcttt ggatttcgct gaaatcacaa caagcactcc tgaaaaatca ttgcttgttg
    30721 cattgaagag caaggctggt cgtaacaaca acggtcgtat cacagttcgt caccaaggtg
    30781 gtggacacaa acgtttctac cgtttggttg acttcaaacg taataaagac aacgttgaag
    30841 cagttgttaa aacaatcgag tacgatccaa accgttctgc aaacatcgct cttgtacact
    30901 acactgacgg tgtgaaagca tacatcatcg ctccaaaagg tcttgaagta ggtcaacgta
    30961 tcgtttcagg tccagaagca gatatcaaag tcggaaacgc tcttccactt gctaacatcc
    31021 cagttggtac tttgattcac aacatcgagt tgaaaccagg tcgtggtggt gaattggtac
    31081 gtgctgctgg tgcatctgct caagtattgg gttctgaagg taaatacgtt cttgttcgtc
    31141 ttcaatcagg tgaagttcgt atgattcttg gaacttgccg tgctacagtt ggtgttgtcg
    31201 gaaacgaaca acatggactt gtaaaccttg gtaaagcagg acgtagccgt tggaaaggta
    31261 tccgcccaac agttcgtggt tctgtaatga accctaacga tcacccacac ggtggtggtg
    31321 aaggtaaagc accagttggt cgtaaagcac catctactcc atggggcaaa cctgctcttg
    31381 gtcttaaaac tcgtaacaag aaagcgaaat ctgacaaact tatcgttcgt cgtcgcaacg
    31441 agaaataata ttaaactagt cgcttaagca actagtaaat ccgccagctc ggtagcgctc
    31501 cataggagtg caagccgctg tggtacaaca tttaaaggag aaaatataaa aatgggacgc
    31561 agtcttaaaa aaggaccttt cgtcgatgag catttgatga aaaaagttga agctcaagct
    31621 aacgacgaaa agaaaaaagt tattaaaact tggtcacgtc gttcaacgat cttcccaagt
    31681 ttcattggtt acactattgc agtttatgac ggacgtaaac acgtacctgt ttacatccaa
    31741 gaagacatgg taggccacaa acttggtgaa tttgcaccaa ctcgtactta caaaggtcac
    31801 gctgcagacg acaagaaaac acgtagaaaa taaggagaac ataaatggca gaaattactt
    31861 cagctaaagc aatggctcgt acagtacgtg tttcacctcg taaatcacgt cttgttcttg
    31921 ataacatccg tggtaaaagc gtagccgatg caatcgcaat cttgacattc actccaaaca
    31981 aagctgctga aatcatcttg aaagttttga actcagctgt agctaacgct gaaaacaact
    32041 ttggtttgga taaagctaac ttggtagtat ctgaagcatt cgcaaacgaa ggaccaacta
    32101 tgaaacgttt ccgtccacgt gcgaaaggtt cagcttcacc aatcaacaaa cgtacagctc
    32161 acatcactgt agctgttgca gaaaaataag gaggtaaaat cgtgggtcaa aaagtacatc
    32221 caattggtat gcgtgtcggc atcatccgtg attgggatgc caaatggtat gctgaaaaag
    32281 aatacgcgga ttaccttcat gaagatcttg caatccgtaa attcgttcaa aaagaacttg
    32341 ctgacgcagc agtttcaact attgaaatcg aacgcgcagt aaacaaagtt aacgtttcac
    32401 ttcacactgc taaaccaggt atggttatcg gtaaaggtgg tgctaacgtt gatgcactcc
    32461 gtgcaaaact taacaaattg actggaaaac aagtacacat caacatcatc gaaatcaaac
    32521 aacctgattt ggatgctcac cttgtaggtg aaggaattgc tcgtcaattg gagcaacgtg
    32581 ttgctttccg tcgtgcacaa aaacaagcaa tccaacgtgc aatgcgtgct ggagctaaag
    32641 gaatcaaaac tcaagtatca ggtcgtttga acggtgcaga tatcgcccgt gctgaaggat
    32701 actctgaagg aactgttccg cttcacacac ttcgtgcaga tatcgattac gcttgggaag
    32761 aagcagatac tacatacggt aaacttggtg ttaaagtatg gatctaccgt ggtgaagttc
    32821 ttccagctcg taaaaacact aaaggaggta aataaccaat gttagtacct aaacgtgtta
    32881 aacaccgtcg tgagttccgt ggaaaaatgc gcggtgaagc aaaaggtgga aaagaagtag
    32941 cattcggtga atacggtctt caagctacaa ctagccactg gatcactaac cgccaaatcg
    33001 aagctgctcg tatcgccatg actcgttaca tgaaacgtgg tggtaaagtt tggattaaaa
    33061 tcttcccaca caaatcatac actgctaaag ctatcggtgt gcgtatggga tctggtaaag
    33121 gggcacctga aggttgggta gcaccagtta aacgtggtaa agtgatgttc gaaatcgctg
    33181 gtgtatctga agagattgca cgtgaagcgc ttcgacttgc tagccacaaa ttgccagtta
    33241 aatgtaaatt cgtaaaacgt gaagcagaat aaggagaagg catgaaactt aatgaagtaa
    33301 aagaatttgt taaagaactt cgtggtcttt ctcaagaaga actcgcgaag cgcgaaaacg
    33361 aattgaaaaa agaattgttt gaacttcgtt tccaagctgc tactggtcaa ttggaacaaa
    33421 cagctcgctt gaaagaagtt aaaaaacaaa tcgctcgtat caaaacagtt caatctgaag
    33481 cgaaataata gactagggaa ggagaaattt caatggaacg caataatcgt aaagttcttg
    33541 ttggacgtgt tgtatctgac aaaatggaca agacaatcac agttgtagtt gaaacaaaac
    33601 gtaaccaccc agtctatggt aaacgtatta actactctaa aaaatacaaa gctcatgatg
    33661 aaaacaatgt tgccaaagaa ggcgatatcg tacgtatcat ggaaactcgc ccgctttcag
    33721 ctacaaaacg tttccgtctt gtagaagttg ttgaagaagc ggtcatcatc taatcaaacc
    33781 tgaaaggaga aaactgaaat gattcaaaca gaaactcgtt tgaaagtcgc agacaacagc
    33841 ggtgctcgcg aaatcttgac tatcaaagtt cttggtggtt caggacgtaa atttgcaaac
    33901 atcggtgatg ttatcgtggc atctgtaaaa caagctactc ctggtggtgc ggttaaaaaa
    33961 ggtgacgttg ttaaagcagt tatcgttcgt actaaatcag gtgctcgtcg tgctgatggt
    34021 tcatacatca aatttgacga aaacgcagca gttatcatcc gtgaagacaa aactcctcgc
    34081 ggaacacgta tctttggccc agttgcacgt gaattgcgtg aaggtggctt catgaagatc
    34141 gtgtcacttg ctccagaagt actttaattt ttaggaacaa actagtcccc tagcttcaag
    34201 ctagggtgcc cttatgggcg taagaaaaat caaggagaaa cctaatgttt gtaaaaaaag
    34261 gcgacaaagt tcgcgtaatc gctggtaaag acaagggaac agaagctgtt gtccttactg
    34321 cccttccaaa agtaaacaaa gttatcgttg aaggtgttaa cattgttaag aaacaccaac
    34381 gtccaactaa cgagcttcct caaggtggta tcatcgagaa agaagcagct atccacgtat
    34441 caaacgttca agttttggac aaaaatggtg tagctggtcg tgttggatac aaatttgtag
    34501 acggtaaaaa agttcgctac aacaaaaaat caggcgaagt gcttgattaa tcacgaagga
    34561 aaggagaagt ataatggcaa atcgtttaaa agaaaaatat cttaatgaag tagttcctgc
    34621 tttgacagaa caattcaact actcatcagt gatggctgtg cctaaagtag ataagattgt
    34681 tttgaacatg ggtgttggtg aagctgtatc aaacgctaaa agccttgaaa aagctgctga
    34741 agaattggca cttatctcag gtcaaaaacc acttatcact aaagctaaaa aatcaatcgc
    34801 cggcttccgt cttcgtgaag gtgttgcgat cggtgcaaaa gttacccttc gtggtgaacg
    34861 tatgtacgaa ttcttggata aattggtatc agtttcactt ccacgtgtac gtgacttcca
    34921 cggtgtccca acaaaatcat ttgatggacg cgggaactac acacttggtg tgaaagaaca
    34981 attaatcttc ccagaaatca acttcgatga cgttgacaaa actcgtggtc ttgacatcgt
    35041 tatcgtaaca actgctaaca ctgacgaaga gtcacgtgca ttgcttacag gccttggaat
    35101 gccttttgca aaataatata ggaggtaaat ctaatggcta aaaaatcaat ggtagctaga
    35161 gaggctaaac gccaaaaaat tgttgaccgt tatgctgaaa aacgtgctgc attaaaggcg
    35221 gcaggggact acgaaggttt atctaaatta cctcgcaacg cctcaccgac tcgtttacat
    35281 aatcgttgta gagttacggg gcgcccacat tcagtttacc gcaaatttgg tctgagtcgt
    35341 atcgcttttc gcgaacttgc gcataaaggt caaattcctg gtgtaacaaa agcatcttgg
    35401 taatttaaga tatcaagggt gtcaaaactc caagtaaaaa taggaaactt gacgaagaaa
    35461 ctaaagtttc taggaaagtt tatctttttc acacagagtt tagcccgggt tcaattgggc
    35521 ttgccaattt gaacccgagc tacagctttg gcaaaaaaga ccaatttgct ttggagcatt
    35581 gcttctgcat taaattgtct atttttgctc gtgctgttac gctctttgta tcatgtatta
    35641 actagcaagt gcaacttgca aactactagt aagaggagaa aaacaaaatg gttatgactg
    35701 acccaatcgc agacttccta actcgtattc gtaatgctaa ccaagctaaa cacgaagtac
    35761 ttgaagtacc tgcatcaaac atcaaaaaag ggattgctga aatccttaaa cgcgaaggtt
    35821 ttgtaaaaaa cgttgaaatc attgaagatg acaaacaagg cgtcatccgt gtatttctta
    35881 aatacggacc aaatggtgag aaagttatca ctaacttgaa acgtgtttct aaaccaggac
    35941 ttcgtgtcta caaaaaacgt gaagaccttc caaaagttct taacggactt ggaattgcca
    36001 tcctttcaac ttctgaaggt ttgcttactg ataaagaagc acgccaaaag aatgttggtg
    36061 gtgaggttat cgcttacgtt tggtaaaatc aagatacaaa gctcgtaaag aacaaagcaa
    36121 aattaggaag ttggagaagt ttgtttacaa acaagccaac ttatctattt tgcacagttc
    36181 ttagagcgtg ttcagttcag ctcttgaact aaataagtat ctgaaccccg tgaaaactgg
    36241 ccgttctggc ctgacaattt aacaggagaa aataaacatg tcacgtattg gtaataaagt
    36301 tatcgtgttg cctgctggtg ttgaactcgc taacaatgac aacgttgtaa ctgtaaaagg
    36361 acctaaagga gaacttactc gtgagttctc aaaagatatt gaaatccgtg tggaaggtac
    36421 tgaagtaact cttcaccgtc caaacgattc aaaagaaatg aaaactatcc acggaactac
    36481 tcgtgccctt ttgaacaaca tggttgttgg tgtatcagaa ggattcaaga aagaacttga
    36541 aatgcgtggg gttggttacc gtgcacagct tcaaggatct aaacttgttt tggctgttgg
    36601 taaatctcat ccagacgaag ttgaagctcc agaaggaatt acttttgaac ttccaaaccc
    36661 aacaacaatc gttgttagcg gaatttcaaa agaagtagtt ggtcaaacag ctgcttacgt
    36721 acgtagcctt cgttcaccag aaccatataa aggtaaaggt atccgttacg ttggtgaatt
    36781 cgttcgccgt aaagaaggta aaacaggtaa ataatgttga gtggttgatc atcaaccacc
    36841 aacctatttt ccaactttgt gcatagcaca cgatttaaaa ctaaagaggt gaaaactgtg
    36901 atttcaaaac cagataaaaa caaactccgc caaaaacgtc accgtcgcgt tcgcggaaaa
    36961 ctctctggaa ctgctgatcg cccacgtttg aacgtattcc gttctaatac aggcatctac
    37021 gctcaagtga ttgatgacgt agcgggtgta acgctcgcaa gtgcttcaac tcttgataaa
    37081 gaagtttcaa aaggaactaa aactgaacaa gccgttgctg tcggtaaact cgttgcagaa
    37141 cgtgcaaacg ctaaaggtat ttcagaagtg gtgttcgacc gcggtggata tctatatcac
    37201 ggacgtgtga aagctttggc tgatgcagct cgtgaaaacg gattgaaatt ctaataggag
    37261 gacactagaa aatggcattt aaagacaatg cagttgaatt agaagaacgc gtagttgctg
    37321 tcaaccgtgt tacaaaagtt gttaaaggtg gacgtcgtct tcgtttcgca gctcttgttg
    37381 ttgttggtga ccacaatggt cgcgtaggat ttggtactgg taaagctcaa gaagttccag
    37441 aagcaatccg taaagcagta gatgatgcta agaaaaactt gatcgaagtt cctatggttg
    37501 gaacaacaat cccacacgaa gttctttcag aattcggtgg agctaaagta ttgttgaaac
    37561 ctgctgtaga aggttctgga gttgccgctg gtggtgcagt tcgtgccgtt gtggaattgg
    37621 caggtgtggc agatattaca tctaaatcac ttggttctaa cactccaatc aacattgttc
    37681 gtgcaactgt tgaaggtttg aaacaattga aacgcgctga agaaattgct gcccttcgtg
    37741 gtatttcagt ttctgatttg gcataagaaa ggggataaaa tggctcaaat taaaattact
    37801 ttgactaagt ctccaatcgg acgcattcca tcacaacgta aaactgttgt agcacttgga
    37861 cttggcaaat tgaacagctc tgttattaaa gaagataacg ctgctatccg tggtatgatc
    37921 acagcagtat ctcacttagt aacagttgaa gaagtaaact aatgaagttt taggggatgt
    37981 gcactgtacc atcccctaaa actagatata gtcatctatg atgacatcgt ataggcgagt
    38041 tgatggggga gacaaccttt tctcccttat cggcgctagc attttacaaa agaggagaaa
    38101 ataaaaatga aacttcatga attgaaacct gcagaaggtt ctcgtaaagt acgtaaccgc
    38161 gttggtcgtg gtacttcatc aggtaacggt aaaacatctg gtcgtggtca aaaaggtcaa
    38221 aaagctcgta gcggtggcgg agttcgcctt ggttttgaag gtggacaaac tccattgttc
    38281 cgtcgtcttc caaaacgtgg attcactaac atcaacgcta aagaatacgc aattgtgaac
    38341 cttgaccaat tgaacgtctt tgaagatggt gctgaagtaa ctccagttgt tcttatcgaa
    38401 gcaggaattg ttaaagctga aaagtcaggt attaaaattc ttggtaacgg tgagttgact
    38461 aagaaattga ctgtgaaagc agctaaattc tctaaatcag ctgaagaagc tatcactgct
    38521 aaaggtggtt cagtagaagt catctaagag aggtgaccta tgttttttaa attattaaga
    38581 gaagctctta aagtcaagca ggttcgatca aaaattttat ttacaatttt tatcgttttg
    38641 gtctttcgta tcggaactag cattacagtt cctggtgtga atgccaatag cttgaatgct
    38701 ttaagtggat tatccttctt aaacatgttg agcttggtgt cggggaatgc cctaaaaaac
    38761 ttttcgattt ttgccctagg agttagtccc tatatcaccg cttctattgt tgtccaactc
    38821 ttgcaaatgg atattttacc caagtttgta gagtggggta aacaagggga agtaggtcga
    38881 agaaaattga atcaagctac tcgttatatt gctctagttc tcgcttttgt gcaatctatc
    38941 gggattacag ctggttttaa taccttggct ggagctcaat tgattaaaac tgctttaact
    39001 ccacaagttt ttctgacgat tggtatcatc ttaacagctg gtagtatgat tgtcacttgg
    39061 ttgggtgagc aaattacaga taagggatac ggaaacggtg tttccatgat tatctttgcc
    39121 gggattgttt cctcaattcc agagatgatt cagggcatct atgtggacta ctttgtgaac
    39181 gtcccaagta gccgtatcac ttcatctatc attttcgtaa tcattttgat tattactgta
    39241 ttgttgatta tttactttac aacttatgtt caacaagcag aatacaaaat tccaatccaa
    39301 tatactaagg ttgcacaagg tgctccatct agctcttacc ttccgttaaa ggtaaaccct
    39361 gctggagtta tccctgttat ctttgccagt tcgattactg cagcgcctgc ggctattctt
    39421 cagtttttga gtgccacagg tcatgattgg gcttgggtaa gggtagcaca agagatgttg
    39481 gcaactactt ctccaactgg tattgccatg tatgctttgt tgattattct ctttacattc
    39541 ttctatacgt ttgtacagat taatcctgaa aaagcagcag agagcctaca aaagagtggt
    39601 gcctatatcc atggagttcg tcctggtaaa ggtacagaag aatatatgtc taaacttctt
    39661 cgtcgtcttg caactgttgg ttccctcttc cttggtgtga tttccatttt accgattgca
    39721 gctaaagatg tatttggtct ttctgatgtt gttgcctttg gtggaacaag tctcttgatc
    39781 attatctcta caggtatcga aggaatcaag caattggaag gttacctatt gaaacgtaag
    39841 tatgttggtt tcatggacag aacagaataa aagtatttac tgaatcagta aatactgagg
    39901 gagtggaggt ttaaactctg acatttgtaa gagttggatc tcccctcttc tattttgttt
    39961 ttaaataggg gtgaaaagac tttttgcttc tatttaaaaa taaaataagg agatcaaatc
    40021 atgaatcttt tgattatggg cttacctggt gcaggtaagg gaactcaagc agcaaaaatc
    40081 gtagaacaat tccatgttgc acatatctca acaggtgata tgttccgcgc tgcaatggca
    40141 aatcaaactg aaatgggtgt tcttgctaag tcatatattg acaagggtga attggttcct
    40201 gacgaagtta caaatggaat cgtaaaagaa cgcctttcac aagatgatat taaagaaaca
    40261 ggattcttat tggatggtta cccacgtaca attgaacaag ctcatgcctt ggacaaaaca
    40321 ttggctgaac ttggcattga actagaaggt attatcaata ttgaagtgaa ccctgacagc
    40381 ctcttggaac gtttgagtgg ccgtatcatc caccgcgtaa ctggagaaac tttccacaag
    40441 gtctttaacc caccagttga ctataaagaa gaagattact accaacgtga agatgataag
    40501 cctgagacag taaaacgtcg tttggatgtt aatattgctc aaggagaacc aatcattgct
    40561 cactaccgtg ccaaaggttt ggttcatgac atcgaaggta atcaagatat caatgatgtc
    40621 ttctcagata ttgaaaaagt attgacaaat ttgaaataaa gcgtttttcg cacttgcaaa
    40681 aatccgctac aaatgttata ctgagatagt ctgacttata attgttgtct ctgtgtctag
    40741 aggcatcgaa tcgaaattta tggaggtgct tttgcgtggc aaaagacgat gtgattgaag
    40801 ttgaaggcaa agtagttgat acaatgccga atgcaatgtt tacggttgaa cttgaaaatg
    40861 gacatcagat tttagcaaca gtttctggta aaattcgtaa aaactatatt cgtattttag
    40921 cgggagatcg tgttactgtc gaaatgagtc catatgactt gacacgtgga cgtatcactt
    40981 accgctttaa ataatcgaaa aacttggagg gataagaaat gaaagtaaga ccatcggtca
    41041 aaccaatttg cgaatactgt aaagttattc gtcgtaatgg tcgtgttatg gtaatttgcc
    41101 cagcaaatcc aaaacacaaa caacgtcaag gataagatag aaaggagaaa acatggctcg
    41161 tattgctgga gttgatattc caaatgacaa acgcgtagta atctcattga cttatgttta
    41221 tggtatcgga cttgcaacat ctaagaaaat tttggctgct gctggaatct cagaagatgt
    41281 tcgtgtacgt gatcttacat cagatcaaga agatgctatc cgtcgtgaag tggatgcaat
    41341 caaagttgaa ggtgaccttc gtcgtgaagt aaacttgaac atcaaacgtt tgatggaaat
    41401 cggttcatac cgtggtatcc gtcaccgtcg tggacttcct gtccgtggac aaaacactaa
    41461 aaacaacgct cgcactcgta aaggtaaagc tgttgcgatt gctggtaaga aaaaataata
    41521 taggaggtaa aagtcttggc taaaccaaca cgtaaacgtc gtgtgaaaaa gaatatcgaa
    41581 tctggtattg ctcatattca cgctacattt aataacacta ttgttatgat tactgatgtg
    41641 catggtaatg caattgcttg gtcatcagct ggtgctcttg gtttcaaagg ttctcgtaaa
    41701 tctacaccat tcgctgctca aatggcttct gaagctgctg ctaaatctgc acaagaacac
    41761 ggtcttaaat cagttgaagt tactgtaaaa ggtccaggtt ctggtcgtga gtcagctatt
    41821 cgtgcgcttg ctgccgctgg tcttgaagta acagcaattc gtgatgtgac tccagtgcca
    41881 cacaatggtg ctcgtcctcc aaaacgtcgc cgtgtataat catcgcatta cactgctttt
    41941 cgtttaagag ggagtaacta aatgatcgag tttgaaaaac caaatataac aaaaattgat
    42001 gaaaataaag attatggcaa gtttgtaatc gaaccacttg aacgtggcta cggtacaact
    42061 cttggtaact ctcttcgtcg tgtacttcta gcttctctac caggagcagc tgtgacatct
    42121 atcaacattg atggtgtgtt acatgagttt gacacagttc caggtgttcg tgaagacgtg
    42181 atgcaaatca ttctgaacat taaaggaatt gcagtgaaat cgtacgttga agacgaaaaa
    42241 atcatcgaac tggatgttga aggtcctgct gaagtaacag ctggtgacat tttgacagat
    42301 agcgatattg aaattgtaaa tccagatcat tatctcttta caatcggtga aggttcttct
    42361 ctaaaagcga ctatgactgt taacagtggt cgtggatatg tacctgctga tgaaaataaa
    42421 aaggataatg caccagttgg aacacttgct gtagattcta tttatacacc agttacaaaa
    42481 gtcaactatc aagtggaacc tgctcgtgta ggtagcaatg atggtttcga caaattaacc
    42541 cttgaaatct tgacaaatgg aacaattatt ccagaagatg ctttagggct ttcagcacgt
    42601 attttgacag aacatcttga tttgtttaca aatcttactg agattgctaa gtcaactgaa
    42661 gtgatgaaag aagctgatac tgaatctgac gaccgtattt tagatcgtac gattgaggaa
    42721 ctggacttgt ctgtgcgttc atacaactgt ttaaaacgtg ccggtatcaa tactgtgcat
    42781 gatttgacag aaaaatctga agcagagatg atgaaagtac gaaatcttgg acgcaagagt
    42841 ttggaagaag tgaaactcaa actcattgat ttgggtcttg gattaaaaga taaataaagg
    42901 aggaatacat ggcttaccgt aaactaggac gcactagctc acaacgtaaa gcaatgcttc
    42961 gcgatttgac aactgacctt ttgatcaacg aatcaatcgt gacaactgaa gctcgtgcta
    43021 aagaaatccg taaaactgtt gaaaaaatga ttactctagg taaacgtggt gatttgcatg
    43081 cacgtcgtca agcagctgct ttcgtacgta atgaaatcgc atctgaaaac tatgatgaag
    43141 caactgataa gtacacttct actacagcac ttcaaaaatt gttctcagaa atcgcacctc
    43201 gttatgctga acgtaacggt ggatacactc gtatccttaa aactgaacca cgtcgtggtg
    43261 atgcagcgcc aatggcgatc atcgaattag tataaaatca tcaattttgt tgagtgttat
    43321 gatgatggag tcttgtgctc ttagtctagc tctggtctac cgctaggatt tcggtcctag
    43381 cgggaacact catcataagt tgggatagta gacgcttgtt tacgaaattg tttttttctt
    43441 aagaacaact tcgtaagcag gcgtttttga gtattttcgt tagaattatg ctatactatt
    43501 tgaaaagaat cctgtttaat gttaaggttt cttattttaa gaagaattgg agtttactta
    43561 tgaaagccat tataactgtt gttggtaaag ataaatctgg aattgttgca ggtgtttctg
    43621 gtaaaattgc agaattagga ttgaatattg acgatatctc tcaaactgtc ttggatgaat
    43681 attttacgat gatggctgtt gtatctagtg atgaaaagca agattttacc tatcttcgta
    43741 atgaatttga agcttttggg caaactttga atgtaaaaat caatattcag agtgcagcga
    43801 ttttcgaagc tatgtataat atctaggagg tcatcatgga tattagacaa gttactgaaa
    43861 ccatcgccat gattgaggag caaaacttcg atattagaac cattaccatg gggatttctc
    43921 ttttggactg tatcgatcca gatatcaatc gtgctgcgga gaaaatctat caaaaaatta
    43981 cgacaaaggc ggctaattta gtagctgttg gtgatgaaat tgcggctgag ttgggaattc
    44041 ctatcgttaa taagcgtgta tcggtgacac ctatttctct gattggggca gcgacagatg
    44101 cgacggacta cgtggttctg gcaaaagcgc ttgataaggc tgcgaaagag attggtgtgg
    44161 actttattgg tggtttttct gccttagtac aaaaaggtta tcaaaaggga gatgagattc
    44221 tcatcaattc cattcctcgc gctttggctg agacggataa ggtctgctcg tcagtcaata
    44281 tcggctcaac caagtctggt attaatatga cggctgtggc agatatggga cgaattatca
    44341 aggaaacagc aaatctttca gatatgggag tggccaagtt ggttgtattc gctaatgctg
    44401 ttgaggacaa tccatttatg gcgggtgcct ttcatggtgt tggggaagca gatgttatca
    44461 tcaatgtcgg agtttctggt cctggtgtgg tgaaacgtgc tttggaaaaa gttcgtggac
    44521 agagctttga tgtagtagcc gaaacagtta agaaaactgc ctttaaaatc actcgtatcg
    44581 gtcaattggt tggtcaaatg gccagtgaga gactgggtgt ggagtttggt attgtggact
    44641 tgagtttggc accaacccct gcggttggag actctgtggc acgtgtcctt gaggaaatgg
    44701 ggctagaaac agttggcacg catggaacga cagctgcctt ggccctcttg aacgaccaag
    44761 ttaaaaaggg tggagtgatg gcctgtaacc aggtcggtgg tctatctggt gcctttatcc
    44821 ctgtttctga ggatgaagga atgattgctg cagtgcaaaa tggctctctt aatttagaaa
    44881 aactagaagc tatgacggct atctgttctg ttggattgga tatgattgcc atcccagaag
    44941 atacgcctgc tgaaaccatt gcggctatga ttgcggatga agcagcaatc ggtgttatca
    45001 acatgaaaac aacagctgtt cgtatcattc ccaaaggaag agaaggcgat atgattgagt
    45061 ttggtggtct attaggaact gcacccgtta tgaaggttaa tggggcttcg tctgtcgact
    45121 tcatctctcg cggtggacaa atcccagcac caattcatag ttttaaaaat taagaaaata
    45181 ggagaaattt taagttctat ttaagattag atgtgtatac tataatcatt aaataaagac
    45241 ctcctaatat tatttgaaac agataacact gaattagttt gaatttgatt ttcatctaat
    45301 atctttattt aatgaactcc taaacttttt cataataatc tccttcaaaa gtcgcctgta
    45361 tgggtggctt ttattttatc attcatgata taatagaagc aaacggagga cggaaaatgg
    45421 taaaagtacg attgtatttg gtacgtcatg gcaagaccat gtttaacacg attggtcgcg
    45481 cgcaaggttg gagcgatact cccttaactg ctgaaggtga acgagggatt caagagttag
    45541 gaatcggttt gcgagaatct gatctacagt ttgagcgcgc ttattcgagt gattctggtc
    45601 gtaccattca gaccatggga attatacttg aagaacttgg cttgcagggg aaaatccctt
    45661 atcgcatgga caagcgtatc agagaatggt gtttcggtag ttttgatgga gcctatgatg
    45721 gcgatctttt catgggcatt attcctcgta tctttaatgt ggaccacgtt caccaattgt
    45781 cttatgctga actggctgag ggcttggtag aggtcgatac agctggttgg gctgaaggtt
    45841 gggaaaaact cagtggccga atcaaggaag gctttgaaat aattgcaaaa gaaatggaag
    45901 atcaaggtgg aggtaacgcc cttgttgtca gccatggaat gactattgga accattgttt
    45961 atctgattaa tggcatgcat ccgcatggtc tagataatgg tagcgtgacg attcttgaat
    46021 atgaggacgg tcagtttagg gttgaagttg tcggtgaccg tagttaccga gagctaggac
    46081 gtgagaagat ggaagaaggt tctatttaat cagtctagac ttgcttgcca tgagctaggg
    46141 atttgataag aatatcaaga taagaaaaaa cagccgaggg tactcctttc ggctgttttt
    46201 gatgtggaaa actaaagtgt aatgctattg cttttagaga ttttcataaa caagagcaag
    46261 gaacctactg ttagaacagt caggatagtt gacaaggctg cggctacacc gtaatttcct
    46321 ctgagaatct ctgtataaat agccacagtc attgttcttg ttttgacatt gtagaggagg
    46381 atagaagtag agagttttga aatcattgtg acccaagata agatggctcc agaaatgata
    46441 ccagatagca tcattggagt tgtaatctta gcaaagatat tgagacgact acttcctaag
    46501 ctttcagcag cttcttcaat acttggtgct atttgttgta agctagcaac agatgagcga
    46561 atagtataag gtaatcttct gacagataga gacataatca agatgaaagc agtccctgta
    46621 atcataagaa atccacttcc aaatagacca gtattgaagg aagaaatgaa ggcaatccct
    46681 agaacggttc ctggtacaat ataaggtacc atactgaggc tgtcaattaa gtttgtaaac
    46741 aaattccgtt ttctaacggc taggtaggag ataaatgtcg caaatagaac aactagaact
    46801 aaggcaatca aagggatacg aatggtattg aaaatagcag atcccatacg attgaaagct
    46861 accttgtaac tgtttggaga ataaccttta acaaatacca tacctgatgt ttttaggaaa
    46921 gaggtataaa ttaagtagat ttgaggtaaa acagagataa agataattcc gtagactgtt
    46981 gcataaatgg cagccatttt tccttttgta gtttttttag gctcaattgg atggagcaga
    47041 ttcatgctga aactgtagcg gtttgcaatg tgtttttgga taaggaaaat tgccaaggca
    47101 atgataatcg ccataattgc aaaagcagaa tttcctccaa cctcgctaat aaattgggta
    47161 taaatcagga cagggaaagt ccgatatcct tcgccaatca acataggcgt tccaaagtct
    47221 gagaatgctc tcataaatac aagcaaggag ctgctagtaa ggttgaaact aggagaggta
    47281 aaacaaccgt tacgataggt ttaaatccga aggcccccat gctttcagct gcttcaagta
    47341 gagaattgtc aatactgttc attgttccag caacatatag aaataccagt gggaatagtt
    47401 gcagtgtaaa gacaagtata cttcctttga atccataaat atcgatagct ggaagatgaa
    47461 gggcatttgt caaaaattta gtgatgacct catttcgtct cagcaagaga atccaggagt
    47521 aggctcctac gaaaggagct gacatggaag caatgataat caatatttgt agaaatttct
    47581 tccccttgaa gtcatacata gagaagagat aagctaatag ggttcctaca actaaggaag
    47641 tgacagtagc ggtaatggaa accctgaaac tgttgactag tgtctcagag tagtaggttt
    47701 tactaaagaa agtgacaaaa ttagctagtg agaattgtcc ttcatgtata agtgcttgct
    47761 tgagcacggt aacgatagga taaacgagaa agacaagata ggtaagaaag atgaagaaag
    47821 aggaagctgt ccaaatattt agttttttac attccatggt tgactccttt tatcaggttt
    47881 tgggaaccat ctgcagaaaa gatgtttaat ttttgcgtat tgattcgtag acgaatacga
    47941 ttgccttttt gtagttcttc ttcaaaagtt gattcttcac taacttgaat ttttgaggca
    48001 aaacctgtct caatgaaata ctccgtattt agtccaagat agacgctatc gctaatagtt
    48061 ccttcaatat ctccagattc atctttgata aactcttcgg gacgaatgct tacatgaata
    48121 gcttgctcct caacctgatc aagagctggc attcgaaggg catagccatc tgaaaagacg
    48181 atataagcgc cgtcgctccg tttttcaaga ttggcaggga taatatttgt gcgtccgata
    48241 aaggttgcca caaactcatt agctggttta tgatagagtt cttttggtcg gccgatttgt
    48301 tggatcaccc catctttcat aacagcaatt tggtctgaaa tagccatggc ttcttcttgg
    48361 tcgtgggtta cataaacagt tgtaattccc acttcgtgtt ggatttctcg gatggcttga
    48421 cgcatatcca agcgaagttt ggcctccaga ttactaagtg gctcgtccat gaggagaaca
    48481 cttggattaa ccgctaaggc gcatgccaag gtgacacgtt gttgttgtcc accactgagt
    48541 ttatcgggtt ttcgatccgc atattgagca atttgcatga gttcaagata cttgttggtc
    48601 tgttgaatca attcttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
    48661 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
    48721 tattgatttt tgtatcatcg aagtaaaatt ctcaatcttt gatactgttg aaacctgcaa
    48781 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
    48841 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
    48901 cgttaataat tttgatctca ctcatagtga acctctttta ctgtttagat tggatatctg
    48961 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
    49021 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
    49081 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
    49141 taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg atagcagcac
    49201 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
    49261 ttaagagttt aactgctgga tcttcataag agagaccaac agtcatttct ccatcagcga
    49321 ctgctttata gacaccagat gaacttaaac cgattttata gta
//
LOCUS       DAVBNN010000009        49183 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBNN010000009 DAVBNN010000000
VERSION     DAVBNN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.009"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..207
                     /locus_tag="VQ847_000521"
     CDS             <1..207
                     /locus_tag="VQ847_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3049912.1"
                     /translation="MDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIK
                     KHLKKVLPSCNTFYEAFLSCSCFN"
     gene            complement(242..1039)
                     /locus_tag="VQ847_000522"
                     /pseudo
     CDS             complement(242..1039)
                     /locus_tag="VQ847_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1304..1540
                     /locus_tag="VQ847_000523"
     CDS             1304..1540
                     /locus_tag="VQ847_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3049913.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1771..3057
                     /locus_tag="VQ847_000524"
     CDS             1771..3057
                     /locus_tag="VQ847_000524"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3049914.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3289..4437)
                     /locus_tag="VQ847_000525"
     CDS             complement(3289..4437)
                     /locus_tag="VQ847_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3049915.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4612..5424)
                     /locus_tag="VQ847_000526"
     CDS             complement(4612..5424)
                     /locus_tag="VQ847_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3049916.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5462..5842)
                     /locus_tag="VQ847_000527"
                     /pseudo
     CDS             complement(5462..5842)
                     /locus_tag="VQ847_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(5855..6118)
                     /locus_tag="VQ847_000528"
     CDS             complement(5855..6118)
                     /locus_tag="VQ847_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3049917.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6118..6351)
                     /locus_tag="VQ847_000529"
     CDS             complement(6118..6351)
                     /locus_tag="VQ847_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049918.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6351..6719)
                     /locus_tag="VQ847_000530"
     CDS             complement(6351..6719)
                     /locus_tag="VQ847_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3049919.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7004..7150
                     /locus_tag="VQ847_000531"
     CDS             7004..7150
                     /locus_tag="VQ847_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049920.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            7194..7568
                     /locus_tag="VQ847_000532"
     CDS             7194..7568
                     /locus_tag="VQ847_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049921.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            7561..7764
                     /locus_tag="VQ847_000533"
     CDS             7561..7764
                     /locus_tag="VQ847_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3049922.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7781..7978
                     /locus_tag="VQ847_000534"
     CDS             7781..7978
                     /locus_tag="VQ847_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049923.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            7989..8150
                     /locus_tag="VQ847_000535"
     CDS             7989..8150
                     /locus_tag="VQ847_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049924.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(8145..8570)
                     /locus_tag="VQ847_000536"
     CDS             complement(8145..8570)
                     /locus_tag="VQ847_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049925.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            8624..9337
                     /locus_tag="VQ847_000537"
     CDS             8624..9337
                     /locus_tag="VQ847_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3049926.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            9350..9607
                     /locus_tag="VQ847_000538"
     CDS             9350..9607
                     /locus_tag="VQ847_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3049927.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9693..10013
                     /locus_tag="VQ847_000539"
     CDS             9693..10013
                     /locus_tag="VQ847_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049928.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            10029..10325
                     /locus_tag="VQ847_000540"
     CDS             10029..10325
                     /locus_tag="VQ847_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049929.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            10318..11145
                     /locus_tag="VQ847_000541"
     CDS             10318..11145
                     /locus_tag="VQ847_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3049930.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            11285..12055
                     /locus_tag="VQ847_000542"
     CDS             11285..12055
                     /locus_tag="VQ847_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3049931.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKDLSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            12070..12264
                     /locus_tag="VQ847_000543"
     CDS             12070..12264
                     /locus_tag="VQ847_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049932.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            12264..12491
                     /locus_tag="VQ847_000544"
     CDS             12264..12491
                     /locus_tag="VQ847_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049933.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            12618..12785
                     /locus_tag="VQ847_000545"
     CDS             12618..12785
                     /locus_tag="VQ847_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049934.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            12953..13282
                     /locus_tag="VQ847_000546"
     CDS             12953..13282
                     /locus_tag="VQ847_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049935.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            13272..13697
                     /locus_tag="VQ847_000547"
     CDS             13272..13697
                     /locus_tag="VQ847_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3049936.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            13697..14211
                     /locus_tag="VQ847_000548"
                     /pseudo
     CDS             13697..14211
                     /locus_tag="VQ847_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            14208..14597
                     /locus_tag="VQ847_000549"
     CDS             14208..14597
                     /locus_tag="VQ847_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049937.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            14597..14833
                     /locus_tag="VQ847_000550"
     CDS             14597..14833
                     /locus_tag="VQ847_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3049938.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKNLDWLIEEMEHE"
     gene            14830..14988
                     /locus_tag="VQ847_000551"
     CDS             14830..14988
                     /locus_tag="VQ847_000551"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049939.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            15200..15601
                     /locus_tag="VQ847_000552"
     CDS             15200..15601
                     /locus_tag="VQ847_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3049940.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            15790..16332
                     /locus_tag="VQ847_000553"
     CDS             15790..16332
                     /locus_tag="VQ847_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3049941.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16496..16687
                     /locus_tag="VQ847_000554"
     CDS             16496..16687
                     /locus_tag="VQ847_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049942.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            16807..17127
                     /locus_tag="VQ847_000555"
     CDS             16807..17127
                     /locus_tag="VQ847_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3049943.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17265..17657
                     /locus_tag="VQ847_000556"
     CDS             17265..17657
                     /locus_tag="VQ847_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3049944.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17650..19380
                     /locus_tag="VQ847_000557"
     CDS             17650..19380
                     /locus_tag="VQ847_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3049945.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19388..19606
                     /locus_tag="VQ847_000558"
     CDS             19388..19606
                     /locus_tag="VQ847_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049946.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19624..20826
                     /locus_tag="VQ847_000559"
     CDS             19624..20826
                     /locus_tag="VQ847_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3049947.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20810..21385
                     /locus_tag="VQ847_000560"
     CDS             20810..21385
                     /locus_tag="VQ847_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3049948.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            21382..22554
                     /locus_tag="VQ847_000561"
     CDS             21382..22554
                     /locus_tag="VQ847_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3049949.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            22566..22856
                     /locus_tag="VQ847_000562"
     CDS             22566..22856
                     /locus_tag="VQ847_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049950.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            22859..23140
                     /locus_tag="VQ847_000563"
     CDS             22859..23140
                     /locus_tag="VQ847_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3049951.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23127..23426
                     /locus_tag="VQ847_000564"
     CDS             23127..23426
                     /locus_tag="VQ847_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3049952.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23423..23770
                     /locus_tag="VQ847_000565"
     CDS             23423..23770
                     /locus_tag="VQ847_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3049953.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            23767..24090
                     /locus_tag="VQ847_000566"
     CDS             23767..24090
                     /locus_tag="VQ847_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049954.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24102..24680
                     /locus_tag="VQ847_000567"
     CDS             24102..24680
                     /locus_tag="VQ847_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3049955.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24692..25111
                     /locus_tag="VQ847_000568"
     CDS             24692..25111
                     /locus_tag="VQ847_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049956.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            25389..28148
                     /locus_tag="VQ847_000569"
     CDS             25389..28148
                     /locus_tag="VQ847_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3049957.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28145..28867
                     /locus_tag="VQ847_000570"
     CDS             28145..28867
                     /locus_tag="VQ847_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3049958.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28868..32089
                     /locus_tag="VQ847_000571"
     CDS             28868..32089
                     /locus_tag="VQ847_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3049959.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVRSLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYT
                     ATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFY
                     AKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQ
                     EGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRAN"
     gene            34085..35467
                     /locus_tag="VQ847_000572"
                     /pseudo
     CDS             34085..35467
                     /locus_tag="VQ847_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            35448..35651
                     /locus_tag="VQ847_000573"
     CDS             35448..35651
                     /locus_tag="VQ847_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049960.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            35654..36005
                     /locus_tag="VQ847_000574"
                     /pseudo
     CDS             35654..36005
                     /locus_tag="VQ847_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36015..36431
                     /locus_tag="VQ847_000575"
     CDS             36015..36431
                     /locus_tag="VQ847_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3049961.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            36435..36770
                     /locus_tag="VQ847_000576"
     CDS             36435..36770
                     /locus_tag="VQ847_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3049962.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRVVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            36770..37726
                     /locus_tag="VQ847_000577"
     CDS             36770..37726
                     /locus_tag="VQ847_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3049963.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(37996..38175)
                     /locus_tag="VQ847_000578"
     CDS             complement(37996..38175)
                     /locus_tag="VQ847_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049964.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(38317..38466)
                     /locus_tag="VQ847_000579"
     CDS             complement(38317..38466)
                     /locus_tag="VQ847_000579"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049965.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            38748..39215
                     /locus_tag="VQ847_000580"
     CDS             38748..39215
                     /locus_tag="VQ847_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3049966.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            39248..39345
                     /gene="ffs"
                     /locus_tag="VQ847_000581"
     ncRNA           39248..39345
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ847_000581"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            39402..39845
                     /locus_tag="VQ847_000582"
     CDS             39402..39845
                     /locus_tag="VQ847_000582"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3049967.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            39847..40362
                     /locus_tag="VQ847_000583"
     CDS             39847..40362
                     /locus_tag="VQ847_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3049968.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            40376..41737
                     /gene="radA"
                     /locus_tag="VQ847_000584"
     CDS             40376..41737
                     /gene="radA"
                     /locus_tag="VQ847_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3049969.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            41810..42307
                     /locus_tag="VQ847_000585"
     CDS             41810..42307
                     /locus_tag="VQ847_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3049970.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            42332..42526
                     /locus_tag="VQ847_000586"
     CDS             42332..42526
                     /locus_tag="VQ847_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049971.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            42508..43131
                     /locus_tag="VQ847_000587"
     CDS             42508..43131
                     /locus_tag="VQ847_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3049972.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            43276..44244
                     /locus_tag="VQ847_000588"
     CDS             43276..44244
                     /locus_tag="VQ847_000588"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3049973.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(44378..44659)
                     /locus_tag="VQ847_000589"
                     /pseudo
     CDS             complement(44378..44659)
                     /locus_tag="VQ847_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(44786..45019)
                     /locus_tag="VQ847_000590"
     CDS             complement(44786..45019)
                     /locus_tag="VQ847_000590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049974.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
     gene            complement(45024..45128)
                     /locus_tag="VQ847_000591"
     CDS             complement(45024..45128)
                     /locus_tag="VQ847_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3049975.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            complement(45343..45693)
                     /locus_tag="VQ847_000592"
     CDS             complement(45343..45693)
                     /locus_tag="VQ847_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3049976.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            45949..48582
                     /gene="polA"
                     /locus_tag="VQ847_000593"
     CDS             45949..48582
                     /gene="polA"
                     /locus_tag="VQ847_000593"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3049977.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            48667..49104
                     /locus_tag="VQ847_000594"
     CDS             48667..49104
                     /locus_tag="VQ847_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3049978.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT        15143 a         8505 c        11305 g        14230 t
ORIGIN      
        1 atggataatg caagattcca tagaatgggg aagttagaac ttttatgcga agagtttggg
       61 cataaacttt tacctcttcc tccctactca cctgagtaca atcctattga gaaaacatgg
      121 gctcatatca aaaagcacct caaaaaggta ttaccaagtt gcaatacctt ttacgaggct
      181 tttttatcct gctcttgttt caattgacta tattagaggc gagacatttt tcggttcttt
      241 gtcaactgta gtgggttgaa gaaagcgaag atctagaaag gacaaatttc gtcctttctt
      301 ttttgaagtt ttcaaagttc ctaaaaccaa aggcattgtg cttgataagt ttgatgagat
      361 tattggtggc ttccagtttg gcgttggaat aaggtaattg aagggcgttg acgattttct
      421 ctttatcttt gaggaaggtt ttaaacagag tctgaaaaag aggtggaaaa gcaagagctg
      481 atagagatta tagtggtgtt tcaagtcttc ggaatagctc aaaagtttat ctagaatttc
      541 tttattagtc aagtgcatac gaaaagtagg gcgataaaat cgtttatcac tcagtttctg
      601 actatcttgt tgaatgagct ttcagtatcg cttgatagcc ttgtattcat gggatttcgg
      661 atgatggctt gtgttctgct ctcaagaaca gttatgatat tgagcttatc aaagtcttga
      721 gcaataaagc tcatttccat ctcccgattg aaacagtcac tccccggact gtttcaacgt
      781 cctaggacat aatctcagga agacgcgaaa aatcatgctc aaagtgaaaa tcattgttct
      841 tgcgaatgac agttgaagtt gaaatagaca actgatgatc aatgtcggtc atagaagtct
      901 ttttaattag cttctgagca atcttttggt tgatgataca aggaatttga tgattcttct
      961 tgacgataga agtttcagcg accatcattt ttgaacagtg atagcactta aaacggcctt
     1021 ttctaagaag aattctagtt tgaatttttt atactagaaa atcagaacca taatacctat
     1081 ataaaaatat tatagttcta ataggattta cccaaaagtt ttaaggcggt ctttttagaa
     1141 ctttaatcgt ttgaaattta ggtagcaaat ttgtttctat tttgtcaact tttcctattt
     1201 ttatcttgtt gaggctggta ttttaacaat tcaggaattg atagtgaatg tgtaaaattt
     1261 tttgttagaa taagtttata aaaaagaaaa ggagtatttg attatgttac aaaaaattta
     1321 tgagcagatg gctaatttct atgatagtat tgaagaagag tatggtccta catttggtga
     1381 taattttgac tgggaacatg ttcattttaa atttttaatt tattatttag tgagatatgg
     1441 cattggttgt cgtagggatt ttatcgttta ccattatcgt gttgcttatc gtttgtatct
     1501 tgaaaaattg gtaatgaatc ggggttttat ttcttgttga ggtaatttta gtaaatttcc
     1561 gaactaattt actcttttat ggaaagataa tagtaaatag ctagtaattt ttctaaatca
     1621 ttttttaata gttggaaata gcaaatcttt ctattgtttc ttcttgataa aaaggcgatt
     1681 ttttattata ataaattgta agatataatt gcaggtgaga gtcctgccat gtatgtgaga
     1741 aaggaagagc ctgagggctc agacaaaatt atgacttcag ttgttgttgt aggtacccaa
     1801 tggggtgatg aaggtaaagg gaagattaca gacttccttt cagcgaatgc agaagtgatt
     1861 gcacgttacc aaggtggtga taatgctggt cacacgattg tgattgacgg taagaaattt
     1921 aagttgcact tgattccatc tgggattttc ttccctgaaa aaatatctgt cattgggaat
     1981 ggtatggttg taaatcctaa atctcttgta aaagagttga gctatcttca tgaggaaggt
     2041 gtaacaactg ataacttacg tatttctgat cgtgcgcatg ttattttgcc ttatcatatc
     2101 gagttggatc gcttgcaaga agaagctaag ggcgacaata agattggtac gacaattaag
     2161 ggaattggtc cagcttatat ggacaaggct gctcgtgttg gaattcgtat tgcagatctt
     2221 ttagataaag atattttccg tgagcgttta gaacgtaacc ttgctgaaaa gaatcgtctt
     2281 tttgaaaaat tgtatgacag taaagcgatt gttttcgatg atatttttga agaatattac
     2341 gaatatggtc aacaaatcaa gaaatacgtg atagatacat ctgttatctt gaatgatgcg
     2401 cttgataatg gcaaacgtgt gctttttgaa ggtgcacaag gtgttatgct agatatcgac
     2461 caaggtactt atccatttgt tacgtcatca aaccctgtag ctggtggtgt gacaattggt
     2521 tctggtgtcg gtccaagcaa gattgacaag gttgtaggtg tatgtaaagc ttatacgagt
     2581 cgtgtaggag atggtccttt cccaactgag ttgtttgatg aagtgggaga acgtatccgt
     2641 gaagtgggtc atgaatatgg tacaacaact ggtcgtccac gtcgtgtagg ttggtttgac
     2701 tcagttgtga tgcgtcatag ccgtcgtgtt tctggtatta ctaacctttc tttgaactct
     2761 attgatgttt tgagcggttt ggatactgtg aaaatctgtg tggcctatga tcttgacggt
     2821 caacgtattg actactatcc agctagtctt gagcaattga aacgttgcaa gcctatctat
     2881 gaagagttgc caggttggtc agaagatatt accggagttc gcaatttgga agatcttcct
     2941 gagaatgcgc gtaactatgt tcgtcgtgtg agtgaattgg ttggcgttcg tatttctact
     3001 ttctcagtag gtcctggtcg tgaacaaaca aatattttag aaagtgtttg gtcctaagag
     3061 atttttaaga tttgtttaag ataggtcggg tatactatag acagttataa gaagacctcc
     3121 taacttgttg taacaaatat cctaaacttt tctttttcat aataatctcc cttaactcca
     3181 cccaatcagg tggagttttt tagctctatt tcaggctttt ggggactatt ctaaaaataa
     3241 tttttcgata tttttcggat tttggtcggg gaattggcgg ggactttttt agcgaatatg
     3301 actaagaaat aggtctgttg tcgcttcagc aagttcgtcc tctacttgat tgtaacgatc
     3361 cgtcatataa acctttgtat gccccagcgc ctggcttaat tgttcaagcg gaacccctgc
     3421 aataatgctt tgagtcgtga agaagtggcg catcatgtga ggtgttacat gcaatcctgt
     3481 tgcttcattc actagattga agtttctatt tagctgattt ggattgatga gaccaccttt
     3541 ctcgttgata gttatataat ccttgtgctg ttccttgata attcctaact ttcgcttaat
     3601 cttagaagct tcagctatca gataatagat caggtctgtt ccgatatcat caaggcagac
     3661 atatcgctct gaatccttcg ttttaagccc tcctttccct tttaaggtct ggttgcttcg
     3721 actgtctcta agatgcagta tagcccgtcc gctgtcgttc tgagtgatgt ccattggacg
     3781 caatccaaag acttctcctc ttctcaatcc aaaaattgtc agataggtca gagcgtagaa
     3841 ttgttttggc ataatctctt ctgcctttgc tatccaagtc ttgaactctt tgagagtcac
     3901 tttcttgttt gcagcaggga tatcactctg gccgatgaaa acacctttca agcgatttga
     3961 gagcagattt ccatttttga cggcatcatt cagcaatgcc atgaagctgg aattgagggt
     4021 ttgaacagtg tatctggtat ggttctgcaa cttttcagcg ataaatagtt catactcatt
     4081 tctatccaaa tttttaagca ggatagaacc aaactttgcc ttgatatggt tcttatagag
     4141 attgtcattg aggtagtagg aagtgtcatt ccagcgccct gttgacaatc tcttttcaga
     4201 atagatatcc caatattgat caagcgttag attcgtattg atacctaatt cttgttcttg
     4261 gatttgttgc tcaagctcta ccaaggctgc acgagcttga gggagagttg tgaaaccact
     4321 tttacttttt tctctttttt tacctcggaa gaaaaaagaa cgtctgacat agtaacgctt
     4381 gcctttagca gtctcatagt aatagatatt tgggtatttt gttttattat atttcattgt
     4441 attctccttg tttatcggct tctggacaag gtctaaacat tgagaatatt gacatcaccc
     4501 ctttcatggt gtaaaatagg gtatagaaaa gaggcctttt taatggctga ttttttataa
     4561 gggtaagctt cacaatcaaa ctttggcgag ggcgattgtg gggctttttt tttattttct
     4621 gaatagtttg tatagtttat acaaactcca agctgtcaaa gggactgcaa ggaatggagc
     4681 gattggaata ccaacaactc caaaaaagac taagaaaaga tacagtgctg aaaatatgat
     4741 tttattggca ggaagttttt tcttaggaga tgtttctgaa agattaatct cgtttactat
     4801 atcagcgaca ctgtcactaa caatattttg ttcaatatgt tcagtttcag ttgttttagt
     4861 ttcaatagct tcagtttccg taacttcttt attggaaatg ttatcatcaa ttatctcaga
     4921 tgattcgctc tgaattactt ctttttgtga agaatcaaca atggtaaggt aaatttcaaa
     4981 accaacatcc aaatcattat ttgtgacaac tttttcttca tactcgtccc attctttata
     5041 tgggccacct tttatctctc cctctattac aaagttatat tttttattat caaaatattt
     5101 tcgtattgtt ttagcaatgg ttgcaggaac atatcctaca tgattatcaa atatcaaaac
     5161 ttttatagca ttaggatcat atctattatc tacttctgga acgagctcaa tattgaaaaa
     5221 gtctaaatct tgatatttga aaactttcag accatattct tcaagttctt ctctaagttc
     5281 cttagttgat aaattgctat agtactttgc atattctggg attccgttat cttcagcaat
     5341 catattgcaa gcttctttta ctgctttttt atattttgtc actccagcga ctctgaataa
     5401 tattttttca acagtctttt gcatatattt cccctctata taaatatctt caatgcaatt
     5461 tttaatttac taatgccaag tactcttcct tgaccatgac ttcattagtc atagttttta
     5521 gattgtagta agacatgaat ttgaggtaat caaactctgt ggggtcgtct aagctttcta
     5581 gtgcgtcttt cacgagatga tggatcatat tcctatcagc ttcgttttca cagcgtaggc
     5641 gagcgttttg gtactctgag cgtgtatggt ctttgtgtcc gagttagtgt agggcgactt
     5701 ggatttgttg ttcaggagct aagttgtggt caatagcgag tacgtttgtg tctggattgt
     5761 agaaaccgct actgtgccag tttgaaccgt cgaagagaca aagctctact tgatattctt
     5821 cgcagagttt agcgagtatc atagttctcc ttcgttattt ataaacatct ctgcggtggg
     5881 cgatttccac ggctaggacg actagtttat cgtcttggat atcacagatg atgcggtaat
     5941 tctctactct gtatcgccag taacctgcaa ggttggcttt tagtgctttt ccgtgttgtc
     6001 gtggattggt cgtgttttca atgtttttag caagccagga taggatttgt tttctggttg
     6061 gggtatctag ttttttaagt tgcttgagag cttttttatc aatatctagc cgatacatta
     6121 agcaatatcc tctcgagata gtcctagttc atccaagacc tcatccatgg tataagtagc
     6181 tgggtcggct aaatactcca tataggcttg gtcggctgct cgtgcgtctt cgatatcttc
     6241 catgagtacc atgaagtcgt caaaatccat ggttgttgtg tcgataccgt gtttggttag
     6301 gtagtccgtg atgtaggagt ttttttctgt gaaattgatc gtgatagtca ttagcgttct
     6361 cctttgcttt tgaagtgggc ggatagaacg gatgtgatga agtcgatatc atcttcattt
     6421 agtggttttc cgtcaaataa catggtgttg gctgctgctt tgcgtaagtc tatgatttgt
     6481 ccatttactt gagcaaattc atcacttcca gcgatagcag gattatctgt ccgtccgagt
     6541 aggtagtcag cacttacatt aaaataatca gctatttctt ttaaaacttt tgaactagga
     6601 ttacttcttt ttaatcgata taaagtatta gttccataac caagtttttc ttctaaaata
     6661 tttatagaaa tcccctgttt atcagctaat tcttttattt tatcgaatgc tacaaacatt
     6721 aatttttcaa cctttctaag caaacgaaaa ataattttaa aatatttgta gaaaatagtt
     6781 gacttattta gtcaaatgtt ttaaaataat attcgtaagc taaagagtta gcgaactaga
     6841 caactaaaaa ataaagcctt acaaaactga ttggcgtccg tttactgtag gtaaaactta
     6901 cttttagtag gtcttttctc tatgttttta ttttaaaaca tttgactaga gttgtcaaga
     6961 agttcgctaa ctttttagat aattttttaa aaggaggtca gggatgaacg aagaagacct
     7021 gaaagaatta ttggaactct tagcgacaga ttatgggcga gggtatctag atggagtagt
     7081 tgggggactt tcaatgcttt tgaaaatttc aaaagaagca gagaaatata gaaaggaaaa
     7141 atatgagtaa agcaaaatta ttagtcacat aaagtaggta aacgaggtag gaaatgatag
     7201 aaacactgga aataaaaata aacaaaaaga catacttcat atctgcaagg gcagatgttc
     7261 cagtcaggta taaagttatg tttggcagaa atctcttcga tgacttttcg aaaataaaaa
     7321 acaataaaga tgaaactcta tcactttgtc tattattttg tatgacagac aaatcgtcag
     7381 aagaattctg taaatttttt attgaaaata attcatatat aacaagtaga catcactatg
     7441 aggcaataag attatttgaa aaacatttta tctttaagcc cgtaacatat tcactagagg
     7501 acatagttca aatcctaaca atatatctag aaaatactaa aacacagatt ggaggaaaaa
     7561 atgagtaaag aactaaaaat aattaaggct aaaattaaaa ctcgtttgat tgagttggat
     7621 atgactcaag tcgaattggc aaaacaagta tctgtagcat catcagttat ttcagagttg
     7681 ctgaagtatg gaaaaggaag tgattatgtg aaagaaaaag tcgtagatat tttgggtatt
     7741 gaaaaccctt gggaaaatag ttagagcatg aggaaatagt atgaacaacg cagcgcaaaa
     7801 agtaacacgg attgacaaag atgcctggga gattgctacg gagctggcga acgagtacgg
     7861 cgtatctatt tgtcacatca tcagcgagag cgtccgctac tgtgcagaga atgccgaatt
     7921 taaggagatg gacgttgtcg ttaaacgatt ggtagtcggc agtaaggtgc tggagtagga
     7981 gggtggagat gaatgaacta gtatggtttt actttgttgt cataatcaat cttatcattg
     8041 gttttgctac atactacgct agcaaaagag atagagaaaa gcgcatcaac gggtttaaaa
     8101 aaatacaaga tgatgagctt gaaagagtta gaaataaatt taatttatga ttttttagaa
     8161 gtcttttgaa taaatctttt atttaagttt tgtttgctat tgcttgcttt attagctatt
     8221 tttaaagctt tgtcaaaatc aacctcgcct gtaaaaactt tgtaggtaag atcattcatc
     8281 ttcatagact tgtcggtttc agtatcaagc tgagatacct tctcaagttc ttgcaaccgt
     8341 aattcatgag cttgtttgat tttttcaagt tcaaaggcat gttgctgttt tagagtatct
     8401 atctgatgat gaaattctct ttcgagtttt tcaacagtat gtgaatgttc tttggcttgt
     8461 ttttcaatct cagctttatt gttagctttt gatgcgacat atgaccataa ccctgatatt
     8521 attgcaagaa taatactaat cacaggttga ataagagctt gatattccat aagatttctc
     8581 caatcgtttt attttaatta taccaaattt agaaaggaac tttatgaacg aaatttttaa
     8641 ttttcacggg caggaagtcc gtactttgat cattgatgac gaaccttggt tcgttgggaa
     8701 agatgttgca gacatcctag gatatagcaa ggctagaaat gcgattgctc ttcatgttga
     8761 tgaagatgac gccctaaaac agggcctcac agataattta ggaagggttc aagaaactat
     8821 catcatcaac gaatctggcc tctactctct tatcttatcc agcaagttgc ctcaggctaa
     8881 agagtttaag cgctgggtga catcagaggt tttgccagct attcgcaagc agggcggttt
     8941 cattcgcgag gacttggacg aggatgcctt tatcgctctg tttactggcc agaagaaatt
     9001 acgtgagcaa caggcgacca tgctggaaga tattgactat ctcaagagtg agcaaccgat
     9061 tcacccaagc tatgctaaat cgctcctgaa gaagcgtaag gctcgggtcg tggtttgctt
     9121 aggtggcatt gatagtccgg cttatgcgga taagactttc gctcagtcag tctttagaca
     9181 agctgagatt gactttaaag accacttcaa cattaatcgc tatgacttgc taccgaaaaa
     9241 attcgcagat gcagccttgg cctattggat gacttgggag ccaagcacca ataccaagat
     9301 gaaaatcatg aaattgaact catttgacga agggtaggag gggaagaaga tggacaatgt
     9361 tctactttca ctgtctgaat ggattaaatc cattatcaag gacacaatca caaggctagt
     9421 cgaaatagaa aaagatagtg accactatcc agagctgatg gatgtgaaca ctacctgtga
     9481 ttttctagga attaagtatg ccaccttttc agataattat cgttacttaa agggatttcc
     9541 aaaggaatta cctggtaaga aatggtcaaa aagagccatc aaagaatggc tctctaatca
     9601 aatataataa ctttactaaa aggcttctgg acaaggtctt agcaaaatta tttgactata
     9661 ttatagcaca aaaagaggat aaggagataa aaatgtttga accaccgatt ttagaccagc
     9721 tgatgggggt tggagcctta ctgcttggat ttgcaggggc ttgccgtcat atcaaattgc
     9781 aggaacaacg caaggaagaa gaaagacgag aagagcaaga atttgcgtct atgattatcc
     9841 aagtgcgtaa tcatgcatat gaacgtggta gagaggacaa atggcaagaa attcgcaaga
     9901 atattcgcag agagttcaaa ggattcacat atgacaacga accgcctgta ggcttgcgtc
     9961 ctgagccgtt agctttgcca gaacctaaac agtctgcaat cagatttttg taatgaggag
    10021 gtcaggaaat gcaagaattg attgaatcgc tggataacct gattatgatt gttaaagaac
    10081 tggaaggaag ggaatcaact tcaagacatt ttattacgat atgggaaaac gattataaaa
    10141 atctattacg agtcaaagaa tacctaaccg actatgaaaa actagcaaag gactatcgtt
    10201 atatgaccct taaaaataag ctgctaaaga ttgaaaaaat ggagctggaa ggcaggtaca
    10261 tctatgaaga tatgcggatg aagtatcgtg ccaatcgcag gaagtggggt gctcggtatg
    10321 tctgaaatca agtggataaa aatcaaaacg gatatttttg acgatgaaaa gatgtgtcta
    10381 attgatgcct cgcctgatcg tgatgcaatt attgtaatct ggatcaaact tataacacta
    10441 gcaggcaaat tgaatacaaa aggcgtacta accatttcta aaaacattgt atacaccgat
    10501 gaaatgcttg cacaaacgtt ccaccgtccg ttgaatacag ttcgtatggc tcttgaagtt
    10561 tttgaaaagt ttggaatggt tgaaaaaatc gatggagtga taatgttacc caattgggag
    10621 aaacatcaga acattgacgg catggaaaaa ataaaagagc aaaatcgaaa tagagcagca
    10681 cgtcaccgac aaaaacagaa attacttgca cagaacaacg aaagtaacgt tactgataac
    10741 gttatggata acgttacagt aacgcatggt aacgcactag ataaagaatt agataaagat
    10801 atagagataa ataataataa ggtgatgatt agttccagcc tttctgaaaa tttgaaaaat
    10861 agcggaatcc atctaactga taagtcacat caacagttac ttgattatgt gggacttgat
    10921 ggaatgagtt tcgatatgtt gaaccgtgca gtcgagaaaa cttccggatc acacaaacct
    10981 agtttcaatt acctaatagc cattcttgaa agttggaaaa agaaaggctt cacatcgatt
    11041 gagcaggtgg atgaggacga ccgtaaatat aaagagggta agaagtcaag acaacaaaac
    11101 gataaaacat cggaacagga ggtaagggac gaatggggat tttagaacta attgagcagt
    11161 tcgagattga ctattatccg ttaagctacg agaagaaaac tcttttagca gaccaaccaa
    11221 ttcatccagt ggttgcctgc ttgtctgaaa tggctagctg gcatgaatgc ggaggtcggc
    11281 tagtatggta gacaatgtgt ttgaggaaat cgccttatct tatcgtagga atacagaaca
    11341 acaagaagag ttctgcgaaa agcataacat ccctttgata aagatattga ggaccgagag
    11401 tgttgtatgt cgcatgtgtg aatctgagcg gattcatgaa gaaaatcagg aaagagtgaa
    11461 tgaactggct aatgctgaga atgagcgaga gaggaaatac tatcttgaaa agttctctct
    11521 ttatgatgaa attttgaaaa atgctacttt ggacaatttt gaaacaccaa ccgaaaaaga
    11581 agcggaaaag ctagcttttg caaagaggat ttgtcgtgag tggtctgagg gtgctaggaa
    11641 caacattgta cttcagggag aagctggaac tggtaagagt catttggctt ttgctatggt
    11701 taaggatcta tctgagtaca cgaaagagat tgctattttt attaacgtaa ctgacttgct
    11761 gatgaagatt aaagctgatt ttagtcagga agagtttctg gtcaataaaa ttgctagtgc
    11821 taagttcttg gttttggatg atttaggaat ggaaaaagat agcgaatggt catttactat
    11881 tctctacaat atcttgaata agcgttcaaa cacaatcatt accacaaatt tgatttctgc
    11941 cgatattcaa aaaagatatg gcagaccttt catgtccaga ctaatgaagg gtgtagataa
    12001 agaccatttg atggttttca atgatttgac aaacaagcga aagcaatatt tttagaatag
    12061 gggtggctga tgtttatttt aaagcatggg acaagagagg ataagccgtt tctaaggtct
    12121 gcaattatca gtgtgactgg cttggatatt tcgtgttctg aggagaagaa agccatgcgg
    12181 tttatttctc gggcggcagc cttacaggtt agcaaggcat tgagaggttc ctttgggaac
    12241 ttctaccctg tcgaggtgga gtgatgttag agctttattt cgtctacaac gggcactgta
    12301 agtttttcct tgggaggttt gacaatgtcg atgatctcat tgagcagatg gaagaccatc
    12361 agtgggcttt ctcagctatc actcatccaa ggtttcagaa gcacattggt cagcggacga
    12421 cacgatttga ctacggttct aaggattgtt actatttagc gactttttca ggaggagaaa
    12481 aaaatgattg aacttattaa agaatttgga atggctattc tgtggttatt tcttggctat
    12541 ttagtcgggg aacgtgcagc aagaaaggaa aagaaagatg atcaataacg ttacattttt
    12601 agtgggaggt aagaaacatg gttggagtaa cctatcagga aattcatctc tttgttgaat
    12661 ttttgaaaga gcagtacggg caaggtcgtc cagactatat tgaagccctg aacgacttag
    12721 acggtctggt ggaagtctcc tacagagaag ctattgaaag atttttagaa gatgaagtac
    12781 gataaacagg ctgagattga cggactgaaa cgcacgatcg agcaaaacga agagaagata
    12841 atcgagtatt cgaagccgtg cgatgcacgc aagagacgga ttagagcgct ggagcgcgat
    12901 ttgttgagga aaaagaataa agaattaaga cggaaagcgg aggagttgga atatgatgga
    12961 agagttaaag caaaaagtta atgaagtata caactggacg gtagaagacg ggaagccgca
    13021 acctcccaag caagatttac cacaagcggt gaaagaccgg gcggactatt tttgggaaat
    13081 ggcagaagat ggtatgacgt ttatgggagc gatggaatgc atcttcgctg atgaaaagcc
    13141 tacagactat gatttgggag ctactaaggg ttggttgcca aaatctaagg agtttgatga
    13201 ttgggttggc tattcgccaa gcatgtctca gttagttatt gcagtttatt tgatttacag
    13261 aggaagcgaa gatgaaactt aatgaattga ttaagaaata taaaaaactt gagggtgtat
    13321 ggaatgctga aggagcagaa ctagttcgtc aaatttttct gcaagacttg gaacaactag
    13381 ataaaccgca accagtcaaa gttccgcagt gtgtggcgga atatatagaa tttaaaaaga
    13441 aaaacaattt tcatgtttac ggtcttgctt ggcttaacgg ctacgaggtc gaaaaagaga
    13501 agcggtattt tgttaagatt aaagggaata ttaaagaaaa tatgttggtt tatggagaac
    13561 ttttgaaaag gtatttcttt acaaaaagct ttagtttaga cgatgttata tattcccaca
    13621 ctcgtaaaga actagaagcc gcaaacttcg gctgggtgtt tgattgccca ggtattgaga
    13681 ttgaggaggt ggaataatgg gagatatacg aatactagac gcttgttgtg gcagtcgtat
    13741 gttttggttt gataaaaatg agagtcatac aactttcatg gacatcagac aagaaaaatt
    13801 tgaaatacat ggaaaaaggt aaacgtaaac cctgacgttg tcggagattt tcgtgatatg
    13861 ccattcgatg gtgaaacatt taatctagta gtatttgatc cgccacattt gaaatgggca
    13921 ggtcaaaact caattatgcg atcacaatat ggccagctgg ataaagttac ctggtcggaa
    13981 gatttagcca agggttttga agaatgtatg agagttctaa aagttggagg tactctagtt
    14041 tttaaatggt ctgattgtca aatcaacgtt aaagaagttc ttaaatctgt accttttaaa
    14101 ccattgtttg gacaacaaag aggtactacg cattggatga cgtttatgaa atttgagaag
    14161 gtcacagaga gaaaggacgg cacgtttgta aaagaggagg atttggcatg ataccgaaat
    14221 ttagagtgtg gcatcatgaa ttaggtagac tgatgtcagt caaatgtatg ttttttcagg
    14281 atagcgagat tgaagaattt gagttaaacg atgctttaat gaatgattac attacagctt
    14341 atcctgatga aatcgaactc atgcaatcaa caggactcaa agacaagaac ggcaaggagg
    14401 tattcatcgg tgacatcgtt aaatgtacaa gaggatgtct ccatgaagta tatttagaaa
    14461 aagaatacgg tggtacattc ataggtggaa tgcctgctgt atacctaaaa ggacttggag
    14521 atggatatgc gtggacggaa tatgaggaaa tcatcggcaa catctacgaa aatccagagc
    14581 ttttggagga taaataatga acccagaaat aattgacaat ataaacaaac caagccacta
    14641 ccaaggtgca aacggtcttg aggctatcga tgttgtgcat aacttcgttg ggagcctttc
    14701 cggagcgtct gctttctttt ggggcaacgc aatcaagtat atgttacggt ttcaaaagaa
    14761 aaatggtctg gaagacctga agaaagctag aaagaatctt gactggctga ttgaggagat
    14821 ggagcatgag tgaatacgca ttgtatgaag gcgacacctt tattaccatg gggacgcttg
    14881 cggaaatcag caaagaaaca ggaattgctg aacggtgcaa gtatttcaga gtttgccatc
    14941 gaagatatct gtacgttttt tgggattgag atccaagaaa ggaaataaaa gtcaatgaac
    15001 aaaagaatta agaagaagat agctaaacgg cagatacaag aaaagcaaga agaattatac
    15061 aaacaactac ggaaattaag ttctgaagaa attgaagcta taactaaaat gattaatcag
    15121 gcagtttcta atattcgcaa ggctttctct cagatatttg ataacttgtt tacatttttg
    15181 aaaaacttgg aggtggaaat tgaaaaaatt gagcgacgaa gaactcaaaa cgttagacag
    15241 agaacttttc aaatttcaaa acattcaacg cacaatagac ttaagaaggc tagaattaga
    15301 aaccagaaac ccagatgctc aaagtgggcc aactgtagga ataagcaaac ctaccgaaac
    15361 tatcgcaatc agaatcgcag atgatccgac tttaaaattt cttgaaggat ttaaagggat
    15421 tattaacaaa ctcttaagca atctagtcga ggaggacaaa gaaattttca atctacgctg
    15481 gagataccct caactgagat gggaagaaat agcagaacag aaattcatga gcaaagctac
    15541 aatctatcga cgtagaagga ttatcttaga acagtacgct ataatgaaag gtgagttgta
    15601 aataagattg agacaaaaga catcttgaag tctcacaaaa aaagggctat tatgatagca
    15661 tgaacttctg aaaacaaaaa cacaaatcac atgttggagt tatcctattt ttacagaaaa
    15721 gttgtttaac agaggaacat catgagtcag caaccagctg gctttttgtt ttgtagaaag
    15781 gaggcagtta tggaatttgt atcaccgata aaagacaatg ataatattca agctatgaaa
    15841 gattatctca gagaatggaa tgagatgtat tatatgctat tcatcacagg cctgaatact
    15901 ggcttacgag tcggagatat acttaccttg aaagttaaag atgttcaagg ttggcacatc
    15961 aaactgagag aacggaagac tggcaagcag ataacaagac ggatgacaaa agaactcaag
    16021 aaagaaatga ggagatatgt tgaaggcaaa ccatttcatc atttcttatt caagagtagg
    16081 caaggtcaga ataaagcgat cactcgtgag cgagcctatc aaatcataca tgaagcagct
    16141 gaagaacttg gcattgataa tgttggcaca catacaatgc gcaagacatt cggctataaa
    16201 tattacaaca agacaaagga cgtaggaaca ttacagaaaa tgttcaatca ctcatcacct
    16261 gcaatcaccc tgagatacat agggatagag caagcagagc ttgatgacgc actacggaac
    16321 tttgtcattt aattttttag atattacttt cacataatga gttaagcata aactgaaaaa
    16381 atgaaagtct tcaaaaccta tgattagtaa gggtttgaga tttagagtga gtttaacaaa
    16441 atataagata tgtgaaagtg agggataaaa ttggtatagt tacaagaggt gaaaaatggt
    16501 aaaagaatac cgtgatgatt ttcttggaga aaaggccttc gagaaattaa ataaagatat
    16561 tgatgccaat cctgaagttg gctttgaaat tgttggatat actcaaacag catttgtaaa
    16621 tggaatgcat ataccgttaa cagccatact agtaaaatgg aataattttt ttaaagaatc
    16681 agaatgagac aaaagacatc ttgaagtctc acaaaaaaag gtttattatg gtagcataga
    16741 tttcttgtat gaggagggga taggtcaaag gcctatccct tttagcattg agaaaggagg
    16801 tttgagatgt ataacaaacc tatcagacca tccttgaaat ctaagaagtg ggagaagttc
    16861 cgtgatagga taatgcgtaa gcatgattat ctttgccaag aaagtttgcg ttacggaatt
    16921 tctgttcaag cagaaatggt acatcatatc tttcctgtgt ctgaatatcc tgagcttgaa
    16981 tttgttgaat ggaattgctt gccattgacg aataagaaac ataatacgtt tcatgataga
    17041 gtgaacgata gagtaatcaa ccaaggattg tattggcaga aaaaaagaaa aaaagaattt
    17101 ttaaattttt tcaaaaatga aaaatgaaaa tttttaatcc ccccctcttt ttgaaaaatc
    17161 attttggcca gtagggtact ggtgaaggga actttttcca agtcgggggc cttcaaacaa
    17221 aaagggggta aaaactaagc gattttgacg aaaggaggta gtttttggct aaaccaatta
    17281 cagcaaagtc gattaagtca aaagtggtca agcagatgaa agacttggga acttatcgta
    17341 aagagttcga aatgatcatt gacatttttg caggtatgtt ataccagtat cagaaacttg
    17401 ctcaagatta tgctgatatg ggttatccag taacagacac ctacgtcaat aaggctggtg
    17461 ctgaaaatga gcgcaaagtt ccaatcttga cagcgatgga aattttgagg aaagatatac
    17521 tcagctactc taatcagttg atgatgaatc ctaagtcgct cggtgaggta gtagaacaag
    17581 agggtgagtc agttcttact gaggtactga agttcaagaa cgaaatcaag aagaagcgag
    17641 tgactggcaa tgggtaatct tgataaagct aaaaaatacg ctcaacacgt cttaactcac
    17701 cgagaagaac attgcgaaga aaacatcctt gctgctgaac gttttttccg tgatttagaa
    17761 aatccaacct ttgagatgga tgaggatatg gtggattttg ttattcactt tatcgagaac
    17821 gtgatagttc atcagcaggg cgatgatatg tttgcggtat ctatccgtaa caagccattg
    17881 cttttgcaac cgtggcaaca tttcgttgta gttaatctgt ttggttttta ctacaagggt
    17941 acgaatgagc gcaggttcaa agaagcgctt atcatgcttg ctcggaagaa tgggaagacc
    18001 tcgtttactg ctgcaatcgc acttgcttat cagatattag atacagatag cggttccaaa
    18061 tgctatatcg ttgctaactc agtcaagcaa gcgatggaag cttttggttt tttaagattc
    18121 aacgttgaac gctggaacga taagaacatt cgtatcaagg ataataacca agaacactct
    18181 atcaccgcca attttggtga tgaaggttct ttctttatcc aggctttagc gaatgatgag
    18241 agccgtctgg actctttgaa cggaaatgtt atcatcttgg acgaagctca cacaatgagg
    18301 aacagtaaga aacatggtct tatgaaaaaa acaatgtcag catacagaaa cagtatgctt
    18361 tttgttatct caacggctgg ggatattcct accgggttcc ttgctaaccg tctgaaatac
    18421 tgtcaaaagg tgctcaagca attagtcact gatgattcat ttttcatctt catctgcaag
    18481 gctaatcaat ctgctgatgg ggacgtggtg aactatctgg acgagaatat cctcaagatg
    18541 gctaatccgt catggggtgt cacggtttcg ctcaaggctc tcaaggaaga agcagagcag
    18601 gctatgaatg atcctcagac aagaaatgag tttttcaata agaccttgaa tatcttcact
    18661 aactctatga acgcttattt taatcctgat gagtttattg cgtcggatag ttgctacgat
    18721 tggagtttag aagagctggc acgtttgcct attcgttggt atggtggtgc ggacttgtca
    18781 agattgcacg acttaacagc tgctgctctc tatggtgtct atcatgacgg tgagaaagac
    18841 gttgatatct gtatcacaca tgctttcttc cctcggatta atgctcagaa aaaagctaat
    18901 gatgacggga ttccactctt tgggtggcag tctgacggtt ggttgacgat gagcaacact
    18961 ccgaccgtcc tctatgatga tatcgtcaaa tggttcatca agatgaggga gaaagggttc
    19021 aagattgctg ctgtcggaat ggataggaag tttggccgtg agttcttgac gaagatgaaa
    19081 caagctcggt tcaagatgat tgaccaacct cagctttttt atctgaaatc agagggattc
    19141 agacggattg agtttaaagt taagaataaa gaattttact atcttcattc tgatgcttac
    19201 gaatactgtg tgagcaatgt tagagcaatt gaaaaggtgg acgatgctgt gcaatatgag
    19261 aaattagatg gagacggtgg gactgcaagg attgacttgt ttgatgccag cgtctttgct
    19321 tgtatacagg ctcttgctaa tcttggcaag ggtggtgatg tgatgagatt ctttgattag
    19381 gtgaattatg aatgaaatag tattatcaga acatgaaatt aacttgctga tcaacaaagg
    19441 gcgagttaaa gtaattttaa acggggaagt agtaactatt cgtcaaagac atatgaaaaa
    19501 tttgatggct gaaacagtaa aatgggaaaa acaggtaatt gatgtcagtc agaatatcgt
    19561 aagaaataaa cactttgatt cactttttca aaatactttt cgttagaaag gaggtgagga
    19621 aacatgggta tttttgaaaa gttttggaaa cgaaacaagc caagtaagtc aatcaacatg
    19681 ctgagtcatt cagatttagg gttgtcaaac ctgatggact cgtatgtacc tttggccaga
    19741 aatccagatg tggtgacagc ggttaataag attgctgatt tggtctctaa tatgaccatc
    19801 cacttgatgg agaatacaga taaaggtgat atcagaatcc gtgatgggct tgctagaaag
    19861 attgatatca atccgtgtaa acacatgaca aggaagtcat ggattttcaa gattgtgcgc
    19921 gatttgcttt tatatggcga tgggaactct gtcctacatg tggaatatga acctgttacg
    19981 gattatattt ctaatctaag accatttccg atgagagagg tttcattcca aacagataag
    20041 gattcctatg taatctcatt taggggtgaa gaatattccc ctgatgaagt agtccacttc
    20101 gtcatcaatc cagatccaga tattccatac attggtactg gttttagggt gacgttgaca
    20161 gatgtggttc aaagtttgaa catggctacc aagactaaaa aaagctttat gaacgggaag
    20221 aatattccta gtcttatcgt taaagtagac tcgtctagtg ctgaactaga ttcggagcaa
    20281 gggcgtgagc gtatcgctga gaagtatttg agtactagca gggttggcgc tccatggatt
    20341 gttccagagg cattgctgga cattcagcag gtaaaaccgc ttagtctaac ggacatcgct
    20401 ttaaacgagt ctgtggaatt ggataaaaga acagttgcag gtctattagg agtacctgct
    20461 tttattttgg gtgtaggaga gttcaacaag acagagtata acaactttgt aaatacgact
    20521 gtcatgagta ttgctaccac tattactcaa acactaacca gggacttact tttgtctagc
    20581 aatcgttact tcaagctaaa tcctcgttca ctcttctctt acaacattac ggagttgtct
    20641 gctgttgctc aacaaatggc aaacagtgct gcaatgcgtc gtaatgagtg gagggattgg
    20701 ctagggatgg ctcctgatcc tgagatggaa gagttgattg ttcttgaaaa ctttctccct
    20761 caggagaaac taggagatca aaataaactg aagggaggtg aggaagagaa tgcaaaagcg
    20821 aaatagctat cgtgccactc aatttcaaac gagagaagaa gaatctggtg atttgatttt
    20881 gagtggctac tttatcaagt ttgacgagga gacggaattg tggccaggct actgtgaagt
    20941 tatcaagcgt gctggtgttg agaaagctgt cacagacgct gatatcagag ctttatttaa
    21001 ccatgatgat agccttgttc tcggtcgaac aggtaacgga actctgacac tgggtgttga
    21061 tgatgttggt ctttttggag atatcatcat taacaaggat gatcctcaag ctgttggggc
    21121 ctatgcccgt gtcaagcgtg gagatgttat agggtgtagc tttggcttta tcccggtaaa
    21181 aatcgaaacg gaagaacgtg aagatggttc atatttggac actgtcttag agctagaaat
    21241 ctttgaagtg agtccatgta ctttcccagc ctatccacaa acggaaattg ctgcacgaca
    21301 aaaagacttc gaaagtcaga agcgtgctaa tcgtgaagcg ctagacaagc gcaagaaaga
    21361 aattaaggag aaatttaatc tatgaacaaa ttattgattt tgggcgctcg tatgcgcaac
    21421 aaagcagaca aagttgtaga gcttgaagaa tcaatcaaag aattgaacaa gcgttctgaa
    21481 cttgaagcta agaaattgga acaagctgga actgacgaag aagtttcagc agttgaaaag
    21541 aaccttgaag acatccaaaa agaatcggat gaaaaggaag cagaaaaaga acaacttgaa
    21601 aaagaaatcg aagatttgaa aaatcaagtt gaagaactaa atcgtaaagc accgacttac
    21661 ccaagtcaag aaaaacgtgg aggacagaaa ttggaacgac gtgacgcaat cgctaaatac
    21721 attcgtactg gtcaaactcg tgacattgta ggcttgaaaa ctactgattc aggaagcgca
    21781 gctttaatcc ctactgaagt tttgaaacct cattttgtta ataaaacacg taatccactt
    21841 ttggatcttg tggaacgtgt gaaagttaat agtggatctg gtaaatatcc agttatcaag
    21901 aaaacggatg gtgtaatggt ttcaatagat gaattgaaat caaatccaga actcggaaaa
    21961 ccagcaatca gcgagattga ttattcaatc aagacttacc gtggatatgt ccctgtgtca
    22021 caagaaatga ttgacgacgc agactatgac atcatgtcca ttgttgaaga cgaagtgttc
    22081 aatcaaggtg acaacactga attgtcatta gttacagctg tcctcaaaac agctacccaa
    22141 gcagatgcgg ctggatttga tggtattaaa gatatctaca acaagaagct taaatcaatt
    22201 tataaagcaa gcatcgttgt aactaagtca atgtttgctg cgcttgacaa agtgaaggac
    22261 aaagatgggc gctacatgct tcaaactgat gtggcttcac ctactggcta ttcatttggt
    22321 gggaaaacaa tctacaaagt agatgacaca gtgtttggaa acgaaggaga tatgaaattc
    22381 ttcatcggag atgttactga gttcgtcaaa gagtttgacc gttctcaagt atccgttaaa
    22441 tgggtgaaca atgacattta cggacaattg cttgggcttt ttatccgttt ggatattaag
    22501 aaagcagatg aagaagctgg attcttcgga acatatactg atgttgtagc ttaaggaggt
    22561 agcgtatgag ctataaagta atccgtcctt tcaaggactt ggctgatcct gaaaatcatg
    22621 actacgctgt tggcgatatc tttcctcgtg agggatatga gccaacagat agctttacca
    22681 atggcctttt gactggcgct aacactgctg gctctatctt ccttgaggtt ttgggagatg
    22741 atgaacctaa gaaaccagcg cctgaaacaa aagaagtgaa ggaagagccc gcagttgagc
    22801 aggaagaaac agttgaggaa actgctgaag agtctgctga ggaagttgag gaatagacat
    22861 ggaccaaggt cagcttttag agttgctgaa gcttaagttg ggtatttcaa ccgacttgag
    22921 agacaagccg ttaaaaaaaa tcatttcaag tgtcatcact gaattgaccg ataatctcgg
    22981 tatcgagctt gttggtgagc gtgctgacca tgaaatgttt atcgttgact atgccgctta
    23041 tcgttatgag ggtggggtgg atatgccacg tcaccttcag tggcgactgc ataatttaca
    23101 gatagcatca aagaaagagg tcaagaatgt ggaatcatga aatcacactg atctccaaga
    23161 aagtaacagg taaggataag ttactacaac caatctctga agatgttgaa gttactctct
    23221 tatgtcgcaa aaagagggtc actcgctctg aattttatca ggcgaatcag gtagggctta
    23281 aaccgagctt ggtcgttgag attcgaaatt ttgagtatga gaatcaagag cttgcgaagt
    23341 tcgaaggcaa gcaatatcat atcttgaaaa cctatcctat tgattctgaa attttagagt
    23401 tgactttgtc agaggtgttg aaatgagtaa tgaccttgct gatttgatag cgaaagagct
    23461 tgcagcttac tctgatgagg ttactgaaga agtggataag attgcagagc aagtgactga
    23521 tgagactgtg gatgagttga aagagacaag tccgaaacgg tacggaaagt atcgtagaag
    23581 ttggaaaaag aagaagttgg ccaatggctc ttttgttgtg ttcaacgcag ttgcaagtct
    23641 tactcacata cttgaaaacg ggcacctttc aagaaatggt ggtcgtgtcg ctggtatcgt
    23701 ccacatcaag ccagctgaag aaaaagcaat tcagaacttt gagaagcgaa tcaaggagat
    23761 tgggaaatga agctatcaga ctttgctgct attttggaac aggcaaactt gcctgtcact
    23821 tatcgagcgt ttaaaattgg aaacgctcct gacctacctt atctggtcta ttatgaatca
    23881 agtccagtca tcaattcagc tgacaacacg gttaatcatc agattaagag cgtgacagtt
    23941 gagctggctt ttgagagtaa ggatgaagat ttggaagaac gtctggaaga gctgtgggca
    24001 aaccacaagc tcttttttga agttcaagaa gaaacattta tcgagactga aagactctat
    24061 gtcaagtctt acacagtcta tctatactaa ggaggaatga catgactcaa gaaaataaag
    24121 taacctttgg cctagaaaat gtacatatcg cacctatcaa gacacttgca gcagatggag
    24181 ttatcactta cggcgatgtt tttcgttttc ctggagcaat agagctgata cttgatacta
    24241 aaggggaaac aacccctatc aaagcagaca acaaggatta ccatttcatg aattcaaacg
    24301 aaggatatga gggtaaactt aaaatcccac acatcattga tgaatttgcg acaaaaattc
    24361 ttggtgaaat caaggaccct caaactggtg ttatgactga aaaagcagat gcgagcttga
    24421 cagagttcgc aatgatgttc cagtttgaag gcgacaaaaa caagactcgc tatgtgatgt
    24481 actactgttt tgccagtcgc ccatctcttg gctcaaaaac taagaacggg acatcaacca
    24541 acgaacgtga acttagtttc aaagctagcc cgcgtccatt ggatacagtt gtcaagcgtt
    24601 ctatcacatc agctgatgac aaggatgcgt atgacaactg gttcaagaaa gtgtatgaac
    24661 ctactgcagt tgcagcttaa ggagaagatc tatgcgtaaa atcgttttgg ttggtgatca
    24721 ggagtatgag ttggggacca acggctatac tcctattgct tacaagcaac aatttggaaa
    24781 agattatttt caagatttgt tctcgatgtt gaaaaatcaa tcattcatga atgaattgaa
    24841 caagttggaa accgacaagg aattgacagc gactaatatt gatatttcga tgttgtcaga
    24901 ttttgacatg acctttttca accgtctttt ttggaccttt gctaaatctg caaatcctca
    24961 catcaagcct tatgaacaat tcttcatgga aatggaaatc ttcccgattc aggaagttgg
    25021 acctgtgctg atggaaatgc taaatgcgag catgacgaca aaaaagcacc agatgagtca
    25081 gaatcagcta gcgaagaaat cttcacagta gaatcctatc tatcttgctg taaagaaact
    25141 ggtctttcta ttgatgatct aaagcacatt tcaatcggaa tggctctgga ttatcagacg
    25201 gattatgtga atctacggag cgaggataag ggtggcgaac ggaaagccac gcaagctgat
    25261 tttgacagtt tttaaagaaa aatgagtgct gagagagcga ttctgagacc aagttccttg
    25321 gtctggctgc attatcagtg gtagaagttc tctcagcgct tttctatttt tttgagaaag
    25381 gaggaaatat ggcaggaaat atcaaaggta tcaaaattga aatcgatggc gacacgcaac
    25441 ccttgcagaa ggcgctgaaa aatgtcaata aggccgctac tgatgcaagt caggagttga
    25501 gacagattga caaggccttg aaatttgata cagggaacgt aacgctcctg actcagaaac
    25561 aagaggtctt acaaaagcaa gtttcgacga ccaaggagaa actggaaacc ttgagacaag
    25621 ctcagtctca ggtggaacag cagttcaaaa atggtgatat cggtgctgat cagtaccgtg
    25681 cctttcaacg cgaagtcgaa gttactcaaa acgtcctaaa aggatatgag ggtaagcttg
    25741 caaatgtgaa tcaggcgctt aatgagaatg ggagtgctac tcagaacaac aagaaccaat
    25801 taaaagagtt gcaaaatgag cagagtcaac ttgcttcaga gatgagtaag gtgacaagtt
    25861 cattcaaact gcaagaaagc gctttgggtt caaatgctag tgaagccgag agaaatgctc
    25921 ttgcccagaa aaagattggt gcccagtctg agattgtaag taaacagatt tcaaatctag
    25981 aacagcaatt ggaaatcact aaaaaagaat ttggtgagaa ctccacacaa gccaacaaga
    26041 tggaatctga gctaaatcag gctaagactg cttttaatca tctcaatgat gagatgaagg
    26101 gaacaaagtc tgctgctgat agcactcaag aaagtttaag tgaaatctca agaaatttaa
    26161 gagcagaact acttcaacag tttagtgaga agttgagtgc tatttcagaa aagcttgtgg
    26221 aagtaggaaa agaagcgtta gaagcagctg ctcaaatgca agctagtaat gctcaattta
    26281 ctaccgtttt cggagatatg gaaacccaag caagagaagc gttgaatgct attggtcagg
    26341 aaatggatat tgtcccagag cgtttacaag ggtcatttac tcagatggct tcatttgcta
    26401 aaacttcagg actagacact gcgcaagcat tggacctgac ttcccgtgca actagggcag
    26461 cggcggatgg cgcagctttt tacgacaagt ccatcgagag cgtatcagaa agcctacaat
    26521 ctttcctgaa aggaaacttt gctaacgatg ccgctcttgg aatctctgcg acagaaacga
    26581 ccaggaatgc agctgcaaat aaattgtacg gaaagtcatt caaggacttg agcgaagcgc
    26641 agaagcaatt gaccttgctt cagatggtcg aagacggaaa taaactctca ggagctcttg
    26701 gacaggctgc aagagaatca gacggcctag aaaacgtgat ggggaatctg aaacaagctg
    26761 ggaccaatgc attatctgct attggtcaac ctcttctaga aatgatgatt cctgtttttc
    26821 aaaccttggc aacgattgtg aaaggtgtgg ccgagctgtt caattccttg cctgatccag
    26881 taaaagattt tgttgttatt ttaggaacag ttgtgactgc tgtaggggtc atagccccca
    26941 tattcttaac cttgcaagcc cttgctgagt ttttaaaaat atctattgga gaaatgataa
    27001 ttgccgcatt gccaattatt ggaacagcta ttgcaattgc tgctgcagtt gctgcaatta
    27061 ttgttattgt aaaatatctc tgggaaacta acgaaggttt tcgagatgcg gtcacgaccg
    27121 tttggaatgc tatactagcc gttatcaata cagttgtttc agaaatctct gatttcatca
    27181 tgagtatatt cgggacggtt gttacttggt ggacggagaa ccaggaactt atcaggacaa
    27241 gtgctgagac tgtctggaat gccatttata cggtcatcag tacaatactg gatatacttg
    27301 gccccttgct ccaagctggc tgggataaca ttcaactgat cattacaaca acttgggaaa
    27361 tcatcaagat cgttgttgag actgcaatca atgttgtcct tggtgttatc caagcagtta
    27421 tgcagatcat tactggtgat tggtcaggag cttgggaaac tatcaaggga gtgttttcta
    27481 ctgtatggca agctattcaa agcattgttc agactatttt ctcagctatc cagagttata
    27541 tttcaaatat tctcaacggc atttcaggaa ctgtatcaaa tatctggaac agcatcaagg
    27601 acactgtctc aaatgtgtta aatgctatat ctagtactgt atcaagtgtt tgggaaggta
    27661 tcaagagtac catttcaagt gctatcaatg gtgcaaggga tgctgtttct tcagctattg
    27721 aagccatcaa aggattgttt aacttcaaca tcagctggcc acatatccca ctacctcact
    27781 tttacgtgag tggttcggcc aatccattag attggttgag tcaaggtgtt ccaagtattg
    27841 gaatcgaatg gtatgccaaa ggcggtatca tgacgaaacc aactatcttt ggaatgaatg
    27901 gtaataacat aatggttggt ggtgaagctg ggaatgaagc agtattgcca cttaacgaca
    27961 aaacgcttgg agccatcggt cgaggtatcg ctcaaactat gggtggaact tcaccaacca
    28021 tcaacattac tattactggt aacaccgtca gagaagaagc tgacatcagt cggattgctg
    28081 atgaggtggc tcagcgtatt gctgacgaat tacaacgtag gagacaattg agaggagggt
    28141 ttgcatgata aagcataatg agcttgtgat tgacggtgtg aggacatcgt cttttccatt
    28201 taagatcatt gtccatgact ctccttcaat cgctctagga gagagcaaga cagctctctt
    28261 ggagcatggt ggtgtcagtg gggcaatcgt tcagacaaac aagcataggg aactggtcaa
    28321 gaaaacttat acgatttact tggtcaaacc tactgaagaa cagatgaacc aatttatgag
    28381 tctgtttatc cgtgaaaagt tctggctaga gagtgagcga gtcaaaacaa ctcgtctttg
    28441 gtgctataag gtcaatgtga gcgaccttga agaagtgcaa cctggtcttt acatgaccaa
    28501 agcaaccttc acttgccatc ctacaaaata ctttaaagac tccgatacac agagattgac
    28561 aagaagtggg actttgaccg ttcaaggttc tgctcttgcc tttcctaaaa tcacaatcgt
    28621 tggtcagagc gcttctgaaa cttcatttac aattgctggt caggtcattc gtcttgaacg
    28681 actcactgag tcgcttgtga tggttaataa tcctgacaat ccaagtttta aaacaacaac
    28741 agggaagcca gtcaaatggt caggggattt tatcacagtt gatccagcga aagtgaagaa
    28801 tattggggtt gttttaggcc caggtattca atcgattgaa atcgaaacgg tttgggggtg
    28861 ggcataattg ctttatctac ttaataaaga tgtaagaacc gttcgatgga acggggagcc
    28921 acttcatgaa gcgacttcgg cgattgtgaa agaaactatg aatggcgatt ttaccttgac
    28981 tgtgaaatat cctatttctg attctggtat ttaccagctc atccaagaag atatgctgat
    29041 aaaggctccg actcctgtct taggagcgca gctatttcgt atcaagaaac ctgttgagca
    29101 caatgaccat ctggaaatca cagcctatca catttcagat gatgtgatgc aacgatctat
    29161 cacacaaatg agtgtgacta gtcagagttg tggcatggct cttgctcgca tggtacaaaa
    29221 caccaaaacg gctcttggag acttctcatt caacagtgat atccaggacc gtaggacatt
    29281 caacacgact gagacagaaa ccctgtactc tgtattgctg gacggcaagc atagtatcgc
    29341 cggaacgtgg gaaggcgagc tggtgcgtga taactttgcg atgactgtaa agaagagtcg
    29401 tggtgagaat cgtggtgttg ttattacaac acataagaat ctgaaggact accaacgaac
    29461 caaaaacagt caaaatgttg ttacaaggat tcatgctcga tccacattta agcctgaagg
    29521 tgctgaaaag gaaacaacta tcagagtgac tgttgatagt cctcttatta attcttatcc
    29581 ttatataaac gaaaaagagt atgagaacaa caacgcaaaa tccgttgaag agttgcagaa
    29641 gtgggcacag tctaagttct caaatgaggg aattgacaag gtctctgatg ctatcaaaat
    29701 tgaagcttat gaacttgatg ggcaagtggt ccatatgggc gacacggtca atctcaagag
    29761 ctggaaacat aatgtcgatg cattcaagaa agctattgct tatgagttcg atgccttaaa
    29821 agaagaatac atctctctga ctttcgatga taaggcaggt attggtggtt ctagatcttc
    29881 tggtggccta tctagcgcag ccgatgcaat tcttggagtg acagaatctg cacaagaaat
    29941 cgcccttgaa aaggctcttc aaaatgctga cttagacttt gatcataagg ctggattgct
    30001 tagacaggaa atttctgacg atattgaact ggccaaagcc agagctgaag aagtcaagag
    30061 agaactgtct gacactatca atcagcgatt taatagcttt gacaacgggc cattgaaaga
    30121 aactaagcgc aaggctgagg aagctttgcg aaatgctggc gcaagtaccc tgcttgcaca
    30181 ggaagctaag cggattgggc tggattctgt cgctagactt gaagcgttta agtcgcagac
    30241 tacgagcgca caaacggctc tgtcgggtga cttggacgct ctgaaacgga ctatcgcgaa
    30301 tgatattcga ccgaagcaag cacaggctga agctgagatt gccaagcaag ctgaagcact
    30361 tagccggact aaaaatgaac tggctggcgc aagtacccta cttgcacagg aagctaagcg
    30421 gattgagctg gattctgttg ctagacttga agcgtttaag tcgcagacta cgagcgctca
    30481 gacggctttg tcaggtgact tggatgttct aaaacaaact atcgcaaacg atattcgacc
    30541 gaagcaagca caggctgaag ctgagattgc caagcaagtt gaagcactta gccggactaa
    30601 gaatgaactg gctggcgtga agtcagcgca agcgacgtat aaggagacga cgactcgtag
    30661 actgtcagaa ctgaccaact tggccaatgg taaagccagc aagtcagaac ttacgcaaac
    30721 agctgaggag ctggctagtc ggattgcgag tgtgcaggca ggtagttcac ggaattactt
    30781 caggaattca cgttcaagaa cgttcacaac aggaggtcaa gcggtatacg actatcgaac
    30841 attcatagtt cctgatttct ggaagaacag tgacaggttc aagcgtgatt atgttcgcat
    30901 atcttttgat gtgactttcc ctgtcgccct agtaaatgac atgcctgcta tggtgcattt
    30961 tagtgctcat ccatggtatg cctacagaaa cttaattttt aaaggtggaa ctgtcgaacg
    31021 ccaacatttt gagtttacga ttgacttgtc tagttcttct gaggactatc agactaataa
    31081 tgtgttcatt cgttttggta ctaattatgg atttcctgct ggtctgcagg tcgtcattga
    31141 gaacgctatg ttatcggttg gtaattattt tccagcctat caaccagcgt atgaagacca
    31201 agaagaccgt gtctcagtag tcgaatccaa ctttaaacag cgtgctgatt cactcgacgc
    31261 tggtgtaaga agcttgactg aaggccttag aaccaaagcg gatatcagct cactcaatgt
    31321 gactgctgaa aatatccggc aatctgtgaa gagccttgag acagatacgc agaacaagct
    31381 aaatcagaag ttgagtcagg ctgaatttga ggtgcgagcc ggctctatcc gtcaggaaat
    31441 cctgaacgca accaaggata aagccagcaa gtcagaactc acgcagacag ctgaggagct
    31501 ggctagtcgg attgcgagtg tgcaggcatc cggtcgaaat ctattcttga actcactatt
    31561 caagcaggat attccaaaaa caggaatttg gacaacgagt acatatacgg ctactatcga
    31621 tagcgaaagt aagtatcttg gacacaaggc tcttaaaatt ataggtttga atccatctgg
    31681 ccgtgatgga ggtaatccca aggttactta tccagctctg ggtcaattcg ggaaagtaat
    31741 tcccggaagt acgactaatc aagatgtaac cattagtttt tatgctaagg caaataaaaa
    31801 tggaataatg ctaagatctc gattagggaa tatcggatat aaaactggaa atgtgacatt
    31861 gtcgacagaa attaagcgat atgttgtcca tattccaaaa ggttggacaa acgaatccaa
    31921 gcagaccaca aatgaatggt tgttcaattt caaccaggaa ggaaccattt ggatttggat
    31981 gccgaagttt gaaataagcg atgtagatac ttcttattca gaagctcctg aagatataga
    32041 aggtcagatt tcaacagttg aatcgacctt caaacaacga gccaactaac tcgacgctgg
    32101 tgtaagccgt ctgactgaag gccttagaac caaagtggat atcagctcac tcaacgtgac
    32161 tgctgaaaat attaggcagt cggtgaagag tcttgagaca gacacgcaga acaagctaaa
    32221 tcagaagttg agtcaggctg aatttgaggt gcgagcaagc ggaatccgtc aggaaatcct
    32281 gaatgcaacc aaggacaagg ctgacaagac cttggtaaca gcggaggctg ggaagttgag
    32341 agaggagctg acaagtctgt cggttggcga gaatctgttt gtaaactcag attttaaaaa
    32401 tctgagggat aacggacagc gttatacagc taacggcaag acctatcaaa acatgattgc
    32461 gccttactgg tacaatccgt acaatgctgg tattccaaat gctcaaaata tccagcatgg
    32521 gtattttgac acggaaacgt ttagtgatac tgtctttgcc tttaacgaga gcgacggctc
    32581 ccgacactgg aaagcattgt caactgattt taaaatcgga gtcatctcag ctggagagta
    32641 ttacttttca gctgatttgt atgcgacaga tttaggcact catatcaaat ttggatttta
    32701 ctatcacaac tcgactggca aactcaattt ttacgcaggt cgaacaaaaa ttgaagttac
    32761 tgaaaaaggc cgttggacta ggctaggaat tgacttaaag gtcaatgatg acattgacct
    32821 gacaaaaaaa gtccaatttt acatttacgg ctataatttt gctagcaact caattttgta
    32881 ccttaaaaag cctaaagtct cgaaaggtcg cttaaaaagc gattggagcc cagctctgga
    32941 agacaccgaa ggcctcatca ctgaggctaa ggcaaccttt gagcggacag ctcagggctt
    33001 gcgaaccgac ttatcagcta ttcaggaata tgtaaataaa gacggtcagc gacaggaagc
    33061 cctacagcgc tatactcgtg aggagagcac gagacaagcg acagcagtcc gtgagctggt
    33121 caatcgtgat ttcgttggta aggctactta tcaagaagat gttaagggta tcaatcagag
    33181 gattgaagct gttaaaacta gtgcgaataa agacatcgct agtcaaatcg ctagctatcg
    33241 tcaatctgta gatggtaagt tcacggatat ttcaagtcag ataactactt ataagcaaga
    33301 tgtgggcggt caaatcagtg gtctatcaaa tagacttaca agcagtgagc aaggaaccac
    33361 tactcagatt tcaaatattt caaatcggat aaacagtaat aaacaaggca cagataatca
    33421 gatttcaaat ttaaagactc aggtcgctac aaacaaggat aatgctgaac gacaaatggg
    33481 tagaatatct gatcaggttt ctgcaaacaa agcgaatgct gatagtcaat ttgcgaatgt
    33541 gaccaatcaa ctagcgcgaa aagtagagac tactgacttc cagcgtgtta aggaaaccag
    33601 taaactttac gagcggattt tgggcaatac tgaaaatgga attgcggata aggttgctcg
    33661 catggctctg accaatcaac tgtttcaggt tgaggttggg aaatatagtg taagcggccc
    33721 taacctcatt aagaatagtg attttaaaaa tggtacgaat gaatggggct caactcaaaa
    33781 tttaggaaga ttggttaagc atagctttta tcacaacggg cagaaagacc ttatgcgttt
    33841 aagtaatgca actaaaaacg aaaacttttt gtatagtcac cgttttaatc ttgaacgaaa
    33901 tactgactat gtactgaatt ttagaggatt taacaacagt gctctcgcaa gctatgatgt
    33961 ttatattttg ggacgaagag caggcgagag cgatggattc acaatcgtta agaaagttgt
    34021 tagcagcaag aaactatcta cctctagatg cgaagatgtc tcagtaactt ttaattccgg
    34081 agaaatggat aatgcttaca ttcgttttga taacaatggc tcatcatcag gaacagctga
    34141 tttgtatatt acagaagttg acttgtacaa aggttataaa cctagaacat ggcaaccaca
    34201 tccagaagat gcagtcgcag atgcgaataa gaagcttgaa gccacgcaaa caaaaatgac
    34261 tcaactagct ggctcatggg tagttgaaaa catcaactcg gctggagata tcatctctgg
    34321 aatcaatctt ggcgccaatg gacataaccg ctttgttggg aaattgaccc acatcactgg
    34381 agagaccctg attgacagag cagtcatcaa gtctgccatg gttgataagc tcaaaacggc
    34441 caattttgaa gctggttcgg tcacgactac gatattagac gctgaagcgg tcacggctga
    34501 taaagtgaga tttgatgctg cgtttattag aaaaatgatt gcaaatgacg cttttattga
    34561 ccaactgaca tctaaacgta tcttctctac taaggttgag tccgtcattt ctagttcaac
    34621 cttcctagaa gcctatcaag gccgaatcgg tggatttaca cttggtcaat ttgatcaggg
    34681 tggcggtcgc tggatttcag gtgtcaatca gttctctgtt ggtatgggga atggtgccgg
    34741 gcatggggtg ccggacagcc ttctgggcga actggggaaa taattggaac tatgccggac
    34801 ctaaagcatg gaacgtcaat actgatggga aaatgtactg taggaatgaa gtcggttttt
    34861 atgatcaagt ggatttttcg aattcatcga gagcaaactt ctatgggaat actacttttt
    34921 ctcgttctcc tgtgttttca aatggtatcg aacttggaag taaagatgtg cttggtgatg
    34981 gttggaatcc caaaggcgga aggaatgcgg ttgtttggtg gaatcaggtc ggtagcggta
    35041 gcgtgaagta ttggatggaa caaaaatcag acagacgctt aaaagagaac atcacagata
    35101 cagctgtgaa agccttggac aaaatcaaca gattaagaat ggttgcattt gatttcatcg
    35161 aaaataagaa acacgaggag attggtctaa tagctcaaga ggctgaaacc atcgttccaa
    35221 gaattgtctc acgagatcct gagaatccag atggctatct acatatcgac tataccgctt
    35281 tagttcctta cttaatcaag gctattcaag aattaaatca aaaaatagaa aaaatggaga
    35341 aaacaatagc atgaataaca acatgttgac caatatcgca cttaaagcaa ttcaggagtt
    35401 tgctcttgaa aatagaaaac gaacacacag attggagaac ttagaaaatg aacacagaac
    35461 agcttaacca agccttacaa atgacaattc gtgaaatgtc aacaacttca acagattcga
    35521 tgattgcaag taatttcttg agtattcagt tgaatgagca aagggaagag aatcaaagac
    35581 ttcaagcacg agtggatgag ctggaagctc tgcttgatga acaaactaaa ccagcagaca
    35641 aaggagaata gacatggcag aaacaattca aaacacagat aacttactag accttacaaa
    35701 aatcacagaa ccatttgatc ttgcgagcgc tttgcgctac atgaaagaaa atggagagtt
    35761 cattcgttgc aagaatgtaa gcgatgactt ctatatgtat cgtgatgttc aaaaacgtcc
    35821 tgtgatcgta aatggccgtc gccaattcaa ggatgttgaa actgtttggg cgttcaacca
    35881 gtgggggggg tacaatcaca acaatcaacg tagccgttct gttgaatcat gaattctata
    35941 tcatgaaatt tgatgcagag ggcaatcctg actggacgga tccaacggta aaacctaaag
    36001 aataggaggt gtgtatgcaa attgaatttt tcaattttct aagaagtgtc gtacagactg
    36061 aagatggttt ggtcttgtac gctctagcac tgattgtctc aatggaaatc attgattttg
    36121 tgacagggac gattgcggcg attatcaatc ctgacatcga gtacaagagc aaaatcggca
    36181 ttaacgggct ccttcgtaag atttcagggg ttctcttact gatgatcctc attccggcgt
    36241 ccgttttgtt gcctgaaaag acaggttttg tattcttgca ctcaatctat ctcgggtaca
    36301 tcgcatttac ttttcaatct ctcattgaaa attaccgcaa attaaaagga aatgttactc
    36361 tttttcagcc gattgtaaaa gtatttcagc gattacttga aaaagatgat gatacgaaaa
    36421 aaggagaata acaaatgcaa caaattactg aaatcattac taatggagca atcagcatcc
    36481 tagtcatttt ggcaggggtg gtagttaggg tagtcaagga atacctcgtc aaaaaaggtg
    36541 gagaaaagac tatcaagatt gttgaaatct tggccaagaa cgcagttaat gccgtggagc
    36601 aggtagctgc tgaaactggc tacaagggag atgaaaaact ggcacaggct cgcgctaaaa
    36661 ttcgtgcaga gctgaccaaa tataatatca gtatgacgga caaggacttg gacacctttg
    36721 tggagtcagc cgtgaagcag atgaacgacg cttggaaagg acaagagtaa tggatatcga
    36781 tagaaacaga ctacgtacag gcttgcccca ggttggggtg cagccttatc gacaagtaca
    36841 tgctcactca acaggcaacc gtaactcaac cgctcaaaat gaagctgatt accactatag
    36901 aaaggaccct gaactagggt tcttttcaca tgttgtcgga aacggccgca tcatgcaggt
    36961 aggacctgtg aacaacggaa gttgggatgt tgggggcggt tggaatgctg agagttatgc
    37021 agcggttgaa ctgattgaaa gccattcaac taaggaagag tttatggctg actatcgcct
    37081 ctatatcgaa ttgctacgca atctagcaga tgaagcaggt ttgccgaaaa cgcttgatac
    37141 agggagttta gctggaatta aaacgcacga gtattgcacg aataaccaac caaacaacca
    37201 ctcagaccac gttgaccctt atccatatct tgcaagttgg ggcattagcc gtgagcagtt
    37261 taagcaagac atcgaaaacg gcttgagcgc tgcgacaggc tggcagaaaa atggtactgg
    37321 ctactggtac gtacactcag acggctctta tccaaaagac aagtttgaga aaatcaacgg
    37381 tacctggtat tatttcgatg gctcaggcta tatgctttca gaccgctgga agaagcacac
    37441 agacggtaat tggtactact ttgaccaatc aggcgaaatg gccacaggct ggaagaaaat
    37501 cgctgagaag tggtactatt ttgatgtaga aggtgccatg aagacaggct gggtcaagta
    37561 caaggacaca tggtactact tagacgctaa agaaggcgcc atggtatcaa atgcctttat
    37621 ccagtcagcg gacggaacag gttggtacta cctcaaacca gacggaacac tggcagataa
    37681 gccagacttc acagtagagc cagatggctt gattacagtt aaataaatag aaaggaaact
    37741 ttctaaattg ttctttcacc gcaggctcag gcttgcggtt tttttgtttg tctgaatcaa
    37801 gaaagcgtct aaccaaccga caccaatgtc ggtagcaaaa taaatggttt gcctaaaaaa
    37861 ttagagttaa gttctatttt tcaaaaacac gcattttgaa cgattagaaa cagaaatcta
    37921 aatcctattg ttcaaaaaaa cgtttacatg aaaaataggg aggtgttttg ttaaaaataa
    37981 aaacagtgat cgaaatcact gcttatcagt tgtagcaaat tcataaagtt tttctgctgt
    38041 gagaagtgcc attttgtcca tgcttgtttt tccttttctg aggtcagaaa cagtagtcca
    38101 tggaactcca gcaccttggg aaatagcaga tgtagacatc gaactgtcta acaattcttg
    38161 aataacttct ctcatcttat ttgtcctttt tattttttag ataaatatat acattgattg
    38221 caattataaa aatagctatt gcactaacca ttgcatttcc tctttccatt tgataaaata
    38281 gaggtgtaag gggctttcgc cccaacctct tagcgtttac ctttttcttt gacgggattt
    38341 cggtttacgc tttttgtttt gccttgcgac cgttattgcg gtcactagac ttgcgatagc
    38401 agttaccgtt tcaggaatat tgtctattgc cttttcaagt aacctgagcc aatcttcttt
    38461 gttcaacttc atcaccccct ttccttatct tgattatatt atatcacggt acaccgagaa
    38521 agtcaagcgt tttgatgaag ttttttttaa ttttttcaaa aaaaaataga ccttgtccag
    38581 aggtcgggga gttggagggg gcaccctcca aaagcattga tttaataagg ttttatttta
    38641 cctttttcat aataatctcc ctatagagtc accgcattcg gtggcttttt ttgtgttggg
    38701 attcatgata taataataaa atcgataagt aggaaaagag aaaagagatg tattatacgc
    38761 ttgaagaaaa agaagtcttt atgagggagg ctttgagaga ggctgagatt gctcttgaac
    38821 acgatgaaat tccaattggt tgtgtgattg tcaaagatgg ggaaatcatt ggtcgtgggc
    38881 ataatgcgcg tgaggaatta cagcgagcgg ttatgcatgc ggaaattatg gctatagagg
    38941 atgcgaactt gagtgaggag agctggcgct tgctggattg cacacttttt gtgaccattg
    39001 aaccttgtgt catgtgtagt ggagcgattg ggcttgcccg cattccaaat gtggtctatg
    39061 gggctaaaaa ccagaaattt ggcgctgctg ggagtttgta caatatcttg acagatgagc
    39121 gtctcaatca tcgtgtggag gttgaaatag gaattttgga agatgaatgc gcagctatca
    39181 tgcaggattt ttttagaaat agacggaaaa aataattttg cttttaaaat gaataggaat
    39241 gtgatataat aaatagtgga gcaacagttc tgcgtgaagc gggtcagggg aggaatccag
    39301 cagccctaag cgatttgaat tgtgtgctct ttttttcgtg ctttttccga ataaataaga
    39361 tagaataatc tagaataaat gataatagaa aagagaaaat tatgaaaatt cgtggttttg
    39421 aattggtttc gagttttaca gatgaaaatt tattgcccaa gcgtgagaca gcgcatgcgg
    39481 ctggttacga cttaaaggtt gctgtgcgta cagttgttgc gccaggagag attgtcttgg
    39541 ttccgacagg ggttaaggct tatatgcagc cgactgaggt tctctacctc tatgatcgtt
    39601 cttcaaatcc tcgtaagaag ggcttggttt taattaactc agttggggtc attgatgggg
    39661 attattatgg aaatcctgga aatgaagggc atatttttgc gcagatgaag aatatcacag
    39721 atcaagaggt tgttcttgaa gttggggaac gtattgtcca ggctgttttt gctactttct
    39781 taattgcaga tggagatgca gctgatggcg ttcgaactgg tggatttgga tcgacagggc
    39841 actagaatga agattatctt tgtacgtcat ggggagccag attaccgtga gttagaggag
    39901 cgttcttata taggatttgg gatagatttg gcacccttgt ctgagatggg acggcagcaa
    39961 gtccagaaat tgagcaaaaa tcctttactc tcgtcagctg aaataatcgt atcttctgca
    40021 gtcacaagag ctttagaaac ggcttcgtat gtggtctgtg ctacgggtct tcctttaaga
    40081 gtagagcctt tattacatga atggcaggtc tataaaacag gaatagaaaa ctttgaaaca
    40141 gctagaagac tgtttttaga aaacaagggg gagttgcttc ctaatagtcc tattcaatat
    40201 gagacagcta cggaaatgaa gtctcggttt ctagaatgta tgtctaagta tcgagaacat
    40261 cagactgtgg tagttgttgc tcatcgaatg ctcatgcgcc agtttgtgcc aaatgagaag
    40321 attgattttt gccaagtgat tgagtgtgag ttagagatat agaaagaggt ttgtcatcgc
    40381 aaagaaaaaa gcgacatttg tatgtcaaaa ttgtgggtat aattccccta aatatctggg
    40441 acgttgcccc aactgtgggt cttggtcttc ttttgtggaa gaggttgagg ttgccgaggt
    40501 caagaatgcg cgtgtgtcct tgacaggtga gaaaaccaag cccatgaaac tagctgaggt
    40561 gacttccatc aatgtcaatc gaaccaagac ggagatggag gaattcaacc gtgtgcttgg
    40621 aggcggagtg gtaccaggaa gtctcgtcct catcggtggg gatcctggga ttgggaaatc
    40681 aactcttctc ctacaagtct caacccagtt gtcccaagtg gggacagttc tctatgtcag
    40741 tggggaggag tctgcccagc agattaaatt acgtgcagag cgcttaggtg atattgatag
    40801 tgagttttat ctctatgcag agaccaatat gcagagtgtt cgtgcagaag tggagcgtat
    40861 ccagccagac ttcttcatta ttgactctat ccagaccatt atgtctcctg agatttcagg
    40921 ggtgcagggg tctgtttctc aggtgcgtga agtgaccgct gaactcatgc agttggccaa
    40981 gaccaataac attgccatct ttatcgtagg tcatgtgacc aaagaaggaa ccttggctgg
    41041 gcctcgtatg ttggagcata tggtggatac ggtgctttac tttgaagggg agcgtcacca
    41101 cacctttcgt attttgagag cggtcaaaaa tcgttttggt tccactaatg agattgggat
    41161 ttttgagatg cagtcgggcg gcttggttga ggtactcaat ccgagtcaag ttttcctaga
    41221 agagcgtttg gatggggcga ctggttcctc catcgttgta accatggaag ggacgcgtcc
    41281 gattttggcg gaggttcagg ctttagtaac accgaccatg tttggaaatg ccaagcgtac
    41341 tacgacagga cttgatttta accgtgctag cttgattatg gctgttttgg aaaaacgggc
    41401 agggcttctc ttgcaaaatc aggatgccta tctcaaatct gctggtggtg ttaaattgga
    41461 tgaacctgcc attgacttgg ctgttgcagt tgctattgct tcgagctaca aagacaaacc
    41521 aactaatcct caggaatgtt ttgtcggaga actgggcttg acaggagaga ttcggcgcgt
    41581 gaatcgtatt gagcaacgca tcaacgaagc tgctaaactg ggctttacta agatttatgt
    41641 acctaagaat tccttgacag gaatcactct gcctaaggaa attcaggtca ttggcgtgac
    41701 aacgattcag gaagttttga aaaaggtctt tgcataatcc gtgacaaatt ctcttaaaaa
    41761 tgataagata ggagaaatat ttgactatca aattttcaag gagggaatcg tgtcgtattt
    41821 tgaacagttt atgcaagcca atcaggctta tgttgcccta catgggcagt taaatctgcc
    41881 acttaaaccc aaaacaagag tagctattgt gacctgtatg gactctcgtc tgcacgttgc
    41941 gcaagctctg ggcttggcac ttggggatgc tcatatcttg cggaatgcag gtggtcgagt
    42001 gactgaagac atgattcgtt cgctagttat ttcccagcaa caaatgggga caagagagat
    42061 tgtggtattg caccatacag actgtggtgc tcagaccttt gaaaatgaac cttttcagga
    42121 gtatttaaaa gaggaattag gtgtagatgt gtcagaccag gatttcttgc ccttccaaga
    42181 tatagaagag agtgtacgcg aggatatgca actgcttatc gagtctcccc taataccaga
    42241 cgatgtcatt atctctggtg ccatttacaa tgttgataca ggaagtatga cagtcgtaga
    42301 attataaata cttcatttag aaagaaagtg tatgaagaaa agcagtattt tattgctatg
    42361 tattggttta cagtatgaaa ccatctacta tacggacggt tcgaggtcag gtgcggaata
    42421 tggactaatg ggaatttcta tctttctagc tctcttttac atgattccgg ctctttattt
    42481 tctcttccgt attgggaaaa atgggaattg ccaaagaagg ttttgattct gtctttattg
    42541 ggagggatgt tcctttcagg ctggttgtct agttttgcta atacttatat ccatgattta
    42601 ctgggggttc ttttcccaga tagtacattt ttaaatgcct ttgaaagtgc tattgtggct
    42661 cctttggtag aagaaccctt gaaattattg ccacttgttt ttgttttggc tttgattcct
    42721 gtgcgaaaat taaaatcttt gtttttactt ggaattgctt ccggtttggg attccaaatg
    42781 attgaggata ttggttatat tcgtacggat ttgccagagg gctttgactt tactatttcg
    42841 cgaattttag agcgtatcat ctcaggaatt gcctctcact ggactttttc aggtctagct
    42901 gtagtaggtg tttacttgct ttacagagcc tataaaggac agaaggttgg caagaaacag
    42961 ggccttattt ttctaggttt agccttggga actcacttct tgtttaactc tccttttgtg
    43021 gagttggaaa cagagttgcc tttagcgatt ccagtggtta cggctattgc tctctatggt
    43081 ttttatcatg cttattgctt tgttgagaaa cacaatgagt tgatgaccta gaatattttt
    43141 caaaagaatg atgcaagggt acaaatatgg tgcccttctt ttatttttga ttgaaaaata
    43201 gtgcaaaaag cgctacaatg gtagatggaa aatcttgtga aaggcacaag ttatacatat
    43261 ataccggagg aaatcatgtc tttttctgat ttaaagctgt ttgccctttc ttctaataaa
    43321 gaattggcag aacgtgtggc gcaggagatt gggatagagt tggggaaatc aagtgttcgc
    43381 caattttcag atggagagat tcaggtcaac attgaagaat caatccgtgg gaaacacgtc
    43441 tttatcttac aatcaactag ttcgcctgta aatgacaatc tgcttgaaat tttgattatg
    43501 gtagatgctt tgaagcgtgc gagtgcagaa tctgtcaatg ttgtcatgcc ttactatggg
    43561 tatgcacgtc aggatagaaa ggcgagagcg cgtgagccaa tcacttcaaa acttgtcgca
    43621 aatatgcttg aagtagctgg agtggatcgt ttattgacca tcgacttgca tgctgcgcaa
    43681 attcaaggat tctttgatat tcctgtggat catttgatgg gtgctcctct gattgcagat
    43741 tattttgagc gtcgtggtat ggttggttct gactatgtgg ttgtcagccc ggaccatgga
    43801 ggggtgactc gtgctcgtaa gttggcagaa tttttgaaaa catctatcgc tattattgat
    43861 aaacgtcgta gcgttgataa gatgaatact agtgaagtta tgaatatcat cggtaaggtt
    43921 gaaggcaaga cttgtatctt gattgatgat atgattgata ccgctggaac gatttgtcat
    43981 gcggcagatg ctcttgcgga agctggtgct gttgaagtct atgcaagctg tacgcaccca
    44041 gttctttctg gtcctgctac ggacaatatc caaaaatcag ctattaagaa attggttgtt
    44101 ttggatacca tctatctgcc agaagagcgt ttgattgata agattgagca gatttcaatc
    44161 gctcatctcc taggggatgc tatcgtacgt attcatgaaa aacgaccact ttctccactt
    44221 ttcgatattg agaaaaaaat ttaatgacca agcctgagat gattctcagg ttttttcgtc
    44281 ttttttccga ataaatagat agtagcggtg aatctagtaa agctagattt aaaactgtga
    44341 tataataaaa agagaagaaa tatgactgta cgtcatcaga agtttcagcg accatcattt
    44401 ttgaacagtg atagcacttg aatcgacgct ttctaaggag aattctagta ggcataccag
    44461 tcgtttcaag ataaggaatt ttagaaggtt tttgaaagtc atatttcttc aattggtttc
    44521 cgcactcagg gcaagatggg gcgtcgtagt ccagtttggc gatgatttcc ttgtgtgtat
    44581 ccttattgat gatgtttaaa atctggacat tagggtcttt aatgtctagt aattttgtga
    44641 taaaatgtaa ttgttccata tgattctttc taatgagttg ttttgtcgct tttcattata
    44701 ggtcatatgg gacttttttt ctacacaaaa taggctccat aatatccata ggggatttac
    44761 ccactatgga tattatggag ccattttaca acagtgcctc aaattcagat actgacatac
    44821 ctaattgctg gctggcaacc tcagaagtca gaagatcttg gcgtactatg tctaggaagg
    44881 caaaaagttt cctttcttcc cttccttcaa ctttcccacg ctctaagcct tgttcaatac
    44941 ctcccgccct agcagtttcc aaggcatagt cctgcgctaa caaggcttgt tcttctcgca
    45001 tacgtagttg actaaacatt ttcctatcct cctcggacca gctcttgtag tccagcagtt
    45061 gatttgcttg ggtaatggct cgttgcggtt gctgggtaaa gggcttgttg ccgaaaaact
    45121 ccaaccatgg cttgcgaacc ttgtctttgc tggtttctct gtatttttta attccaagaa
    45181 tgccatctta accagatggt tttcctgtcc attgttggta atcgccaata cctcacctgt
    45241 tgtgtcttcg cgcatactaa agctatgaaa agccaggtca tctgagaaat aattactatc
    45301 cacgatagca atgacgtaaa caggagcgat gtgtttgtag atctagtgag tatcaccttc
    45361 tcgctgacga attttttcaa gattttgatt aacctgactg cacaggtaag cccacaagtg
    45421 attgatgaaa aaattctgat gatggacttg aatctcaata attacttgag taccgttatc
    45481 caactccgcc aagacgtcta tactggtata aaaatcctgc accgagtaag gcatggagag
    45541 taatacgtga atatcgcttc cctccaaaat ggtcacattt tttgctggca agtccagcat
    45601 atcgcgaata aattgacaag tgatttctgg attgctgaat attttcttag caatcaaatc
    45661 attagttggg ctgatgcccg gatgtctgag aatcctccta ttcctccttc tatagtgagt
    45721 tgaaataaga tgtgaataac tctatcagga aagtcaaatt aatttataga aatattttag
    45781 cagtcaaggt gtactattat agattcaata tactatatta tagcacattt ttaaatctag
    45841 gtttactaaa ttctctggct ctatctattt attcggaaaa agtttgaaaa atacttgctc
    45901 tagctcttcc caatggtatt ttttgattct ttcctttata atgggtgtat ggataagaaa
    45961 aaattattat tgattgatgg gtcttctgta gcttttcggg cgttttttgc gctgtatcag
    46021 cagttggacc gttttaagaa tgcggctggt ttgcatacca atgcgattta tggttttcag
    46081 ttgatgttga gtcatttgtt ggagcgggtt gagccgagtc atattttggt ggcttttgat
    46141 gcgggaaaga cgaccttccg gacagagatg tatgcggact ataagggtgg tcgggccaag
    46201 actcctgatg agtttcgtga gcaatttcct ttcattcgtg agttgctgga tcatatgggg
    46261 attcgtcact atgagctggc tcagtatgag gcggatgaca tcattgggac gctggataag
    46321 ctagcagagc aggatggttt tgatattacc attgtcagtg gggacaagga tttgattcag
    46381 ctgacggatg agcatacggt ggttgaaatt tccaagaaag gtgtggctga gtttgaggcc
    46441 tttacgccag attacctcat ggaagaaatg ggcctcacac cagctcagtt tatcgatctc
    46501 aaggcgctca tgggtgataa gtcggataat atccctgggg tgaccaaagt cggtgaaaag
    46561 acgggtatta agctcttgct ggagcatggt tcgcttgagg ggatttatga aaatattgat
    46621 ggaatgaaga cttctaagat gaaggaaaat ctcatcaatg acaaggaaca ggccttttta
    46681 tctaaaacac tagcgaccat tgataccaag gcaccgattg cgattggttt agaggacttg
    46741 gtctatagtg gtccagatgt tgaaaatctt gggaaattct acgatgagat gggcttcaaa
    46801 cagctaaagc aggctttaaa tgtgtcgtca gctgatgtgt ctgagagttt ggattttact
    46861 attgttgacc aaatcagtca agatatgctg agtgaagagt ctatcttcca ctttgagctt
    46921 tttggtgaga attaccatac ggataatttg gttggatttg cctggtcttg tggggataag
    46981 ctctatgcca cagacaagct tgagctgttg caagacccga ttttcaagga tttcttagaa
    47041 aaaacatctc tgagagttta tgactttaag aaggttaaag ttcttttgca acgttttggt
    47101 gtggatttgc aggcgcctgc ttttgacatc cgtttggcta aatacctcct ttcgactgtg
    47161 gaggacaatg aaattgcgac catcgctagt ctttatggtc agacttactt ggttgatgat
    47221 gaaactttct acggtaaggg tgttaaaaag gccattcctg aacgtgagaa attcttggaa
    47281 cacttagctt gtaaacttgc tgttttggta gaaacagagc ctattttact tgaaaaactc
    47341 agcgaaaatg ggcaattaga gcttctttat gatatggagc aacctctggc ttttgtcctt
    47401 gccaagatgg aaattgctgg gattatggtc aagaaagaga ccttgcttga gatgcaggct
    47461 gaaaatgagc ttgtcattga aaaactgact caagagattt acgagctggc tggtgaggag
    47521 tttaatgtca actcgcctaa gcagttgggc gtgcttctct ttgagaaatt gggacttcct
    47581 ctagaataca ctaagaaaac caagacaggt tattcgacag cagtggatgt gttggagcgt
    47641 ctcgctccta ttgctccgat tgttaagaaa atcctggatt accgtcaaat tgctaagatt
    47701 caatctactt atgtaattgg cttgcaggac tggattttgg ctgatggaaa gattcatact
    47761 cgctatatgc aggatttgac ccagaccggg cgtttgtcta gtgtggatcc aaacttgcaa
    47821 aatattcctg cccgattgga acaagggcgc ttgattcgga aggcttttgt gccagagtgg
    47881 gaggatagtg tgctactcag ctctgactat tcacagattg aattgcgcgt tttggcgcat
    47941 atttctaagg atgagcactt gattaaggcc ttccaagagg gggcagatat ccatacttcg
    48001 acagccatgc gggtctttgg cattgagcgt cctgataatg tgactgcaaa tgatcgtcgc
    48061 aatgccaagg cagttaactt tggagtggtt tatgggattt cagactttgg cttgtctaat
    48121 aatttgggaa ttagtcgtaa ggaagccaaa gcctacattg atacctactt tgaacgtttt
    48181 ccaggtatta aaaactacat ggatgaagtg gtgcgggagg cgcgtgataa gggctatgta
    48241 gagaccctct ttaagcgtcg ccgtgagttg ccagatatca attcgcgcaa cttcaatatt
    48301 cgtggttttg cggagcgaac tgctatcaac tcacctatcc agggttcggc agcagatatt
    48361 ctcaagattg ccatgattca gctggataaa gccttggttg caggtggtta tcagactaag
    48421 atgctgttac aagtgcacga tgaaatcgtc cttgaagtgc ctaaatctga attggtagag
    48481 atgaaaaaat tggtgaaaca aaccatggaa gaagccattc aactcagtgt tcctcttatc
    48541 gcagatgaga atgaaggggc aacctggtac gaggctaaat aaaaaggggg ctagtcctcc
    48601 ttttttgtag tagaattctg caaacctttt caaaatgtgc tatactgatg aaaaaggagg
    48661 ttttctatga gtcaagaatt tatcaatcca agtgatggcg tgattcgtca gtatctcgca
    48721 acgagtaaaa cccttgctgt ggtgggtttg tctgaccgtg aagaaacaac cagcaatcga
    48781 gtgacaaagg aaatgcaggc tcggggctat aaaatcatcc cagtcaatcc caaggcggca
    48841 ggtggcgaaa tcttgggtga aaaggcttat gctagcctcg ctgaaattcc ttttcctgta
    48901 gatattgtca atgtttatcg tcgcagtgaa tttctgcccg atgtggcgcg tgattttctc
    48961 aaagctgatg ccaagatttt ttgggcacag ctaggacttg aaagtttaaa agcgaaagag
    49021 attttgcgtg atggtggatg tgatgatatc gtgatgaatc gctgtatcaa gagagaacat
    49081 actcgcttga ttgaggaagc ataagaaaaa ggtagctgat gggctacctt ttgtgttata
    49141 ctcaatgaaa atcaaagagc aaactaggaa actagccgcg ggc
//
LOCUS       DAVBNN010000010        47724 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBNN010000010 DAVBNN010000000
VERSION     DAVBNN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.010"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(790..1050)
                     /locus_tag="VQ847_000595"
     CDS             complement(790..1050)
                     /locus_tag="VQ847_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049979.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(1109..1660)
                     /locus_tag="VQ847_000596"
     CDS             complement(1109..1660)
                     /locus_tag="VQ847_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049980.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1650..1847)
                     /locus_tag="VQ847_000597"
     CDS             complement(1650..1847)
                     /locus_tag="VQ847_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049981.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1851..2435)
                     /locus_tag="VQ847_000598"
     CDS             complement(1851..2435)
                     /locus_tag="VQ847_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049982.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2833..3258)
                     /locus_tag="VQ847_000599"
     CDS             complement(2833..3258)
                     /locus_tag="VQ847_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049983.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3387..3746)
                     /locus_tag="VQ847_000600"
     CDS             complement(3387..3746)
                     /locus_tag="VQ847_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049984.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(3792..3998)
                     /locus_tag="VQ847_000601"
     CDS             complement(3792..3998)
                     /locus_tag="VQ847_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049985.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            complement(3985..4146)
                     /locus_tag="VQ847_000602"
     CDS             complement(3985..4146)
                     /locus_tag="VQ847_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3049986.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4505..5461)
                     /gene="lytA"
                     /locus_tag="VQ847_000603"
     CDS             complement(4505..5461)
                     /gene="lytA"
                     /locus_tag="VQ847_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3049987.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5837..7207)
                     /locus_tag="VQ847_000604"
     CDS             complement(5837..7207)
                     /locus_tag="VQ847_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3049988.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(7514..8680)
                     /gene="recA"
                     /locus_tag="VQ847_000605"
     CDS             complement(7514..8680)
                     /gene="recA"
                     /locus_tag="VQ847_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3049989.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(8735..9991)
                     /locus_tag="VQ847_000606"
     CDS             complement(8735..9991)
                     /locus_tag="VQ847_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3049990.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(10076..11092)
                     /locus_tag="VQ847_000607"
     CDS             complement(10076..11092)
                     /locus_tag="VQ847_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3049991.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(11100..11618)
                     /locus_tag="VQ847_000608"
     CDS             complement(11100..11618)
                     /locus_tag="VQ847_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3049992.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(11608..12051)
                     /gene="tsaE"
                     /locus_tag="VQ847_000609"
     CDS             complement(11608..12051)
                     /gene="tsaE"
                     /locus_tag="VQ847_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3049993.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(12137..12757)
                     /locus_tag="VQ847_000610"
     CDS             complement(12137..12757)
                     /locus_tag="VQ847_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049994.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(13140..14003)
                     /locus_tag="VQ847_000611"
     CDS             complement(13140..14003)
                     /locus_tag="VQ847_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3049995.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            14192..14362
                     /locus_tag="VQ847_000612"
     CDS             14192..14362
                     /locus_tag="VQ847_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3049996.1"
                     /translation="MKKNRGIQKLAILVLLGVFMLSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            14507..16522
                     /locus_tag="VQ847_000613"
     CDS             14507..16522
                     /locus_tag="VQ847_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3049997.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            16524..17156
                     /locus_tag="VQ847_000614"
     CDS             16524..17156
                     /locus_tag="VQ847_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3049998.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            17297..17575
                     /locus_tag="VQ847_000615"
     CDS             17297..17575
                     /locus_tag="VQ847_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3049999.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(18084..18497)
                     /gene="ndk"
                     /locus_tag="VQ847_000616"
     CDS             complement(18084..18497)
                     /gene="ndk"
                     /locus_tag="VQ847_000616"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3050000.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(18608..22285)
                     /gene="rpoC"
                     /locus_tag="VQ847_000617"
     CDS             complement(18608..22285)
                     /gene="rpoC"
                     /locus_tag="VQ847_000617"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3050001.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(22318..25929)
                     /gene="rpoB"
                     /locus_tag="VQ847_000618"
     CDS             complement(22318..25929)
                     /gene="rpoB"
                     /locus_tag="VQ847_000618"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3050002.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            26345..26415
                     /locus_tag="VQ847_000619"
     tRNA            26345..26415
                     /locus_tag="VQ847_000619"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26377..26379,aa:Cys,seq:gca)
     gene            complement(26613..27944)
                     /locus_tag="VQ847_000620"
     CDS             complement(26613..27944)
                     /locus_tag="VQ847_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3050003.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(28235..29059)
                     /gene="endA"
                     /locus_tag="VQ847_000621"
     CDS             complement(28235..29059)
                     /gene="endA"
                     /locus_tag="VQ847_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3050004.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(29098..29286)
                     /locus_tag="VQ847_000622"
     CDS             complement(29098..29286)
                     /locus_tag="VQ847_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3050005.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(29279..30562)
                     /gene="murA"
                     /locus_tag="VQ847_000623"
     CDS             complement(29279..30562)
                     /gene="murA"
                     /locus_tag="VQ847_000623"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3050006.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(30586..30816)
                     /locus_tag="VQ847_000624"
     CDS             complement(30586..30816)
                     /locus_tag="VQ847_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3050007.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(30874..31911)
                     /locus_tag="VQ847_000625"
     CDS             complement(30874..31911)
                     /locus_tag="VQ847_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3050008.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(31895..32383)
                     /gene="coaD"
                     /locus_tag="VQ847_000626"
     CDS             complement(31895..32383)
                     /gene="coaD"
                     /locus_tag="VQ847_000626"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3050009.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(32373..32912)
                     /gene="rsmD"
                     /locus_tag="VQ847_000627"
     CDS             complement(32373..32912)
                     /gene="rsmD"
                     /locus_tag="VQ847_000627"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3050010.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(32977..33969)
                     /locus_tag="VQ847_000628"
     CDS             complement(32977..33969)
                     /locus_tag="VQ847_000628"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3050011.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(34080..34763)
                     /locus_tag="VQ847_000629"
     CDS             complement(34080..34763)
                     /locus_tag="VQ847_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3050012.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(34819..35559)
                     /locus_tag="VQ847_000630"
     CDS             complement(34819..35559)
                     /locus_tag="VQ847_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3050013.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            35593..35871
                     /locus_tag="VQ847_000631"
     CDS             35593..35871
                     /locus_tag="VQ847_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3050014.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            35949..36875
                     /gene="yidC"
                     /locus_tag="VQ847_000632"
     CDS             35949..36875
                     /gene="yidC"
                     /locus_tag="VQ847_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3050015.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(36950..37744)
                     /gene="pflA"
                     /locus_tag="VQ847_000633"
     CDS             complement(36950..37744)
                     /gene="pflA"
                     /locus_tag="VQ847_000633"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3050016.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(37870..39120)
                     /locus_tag="VQ847_000634"
     CDS             complement(37870..39120)
                     /locus_tag="VQ847_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3050017.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(39187..40014)
                     /gene="purR"
                     /locus_tag="VQ847_000635"
     CDS             complement(39187..40014)
                     /gene="purR"
                     /locus_tag="VQ847_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3050018.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(40281..41222)
                     /locus_tag="VQ847_000636"
     CDS             complement(40281..41222)
                     /locus_tag="VQ847_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3050019.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(41212..42468)
                     /locus_tag="VQ847_000637"
     CDS             complement(41212..42468)
                     /locus_tag="VQ847_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3050020.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(42470..43132)
                     /locus_tag="VQ847_000638"
     CDS             complement(42470..43132)
                     /locus_tag="VQ847_000638"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3050021.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(43095..43751)
                     /locus_tag="VQ847_000639"
     CDS             complement(43095..43751)
                     /locus_tag="VQ847_000639"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3050022.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(43762..44640)
                     /gene="rsgA"
                     /locus_tag="VQ847_000640"
     CDS             complement(43762..44640)
                     /gene="rsgA"
                     /locus_tag="VQ847_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3050023.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(45233..46006)
                     /locus_tag="VQ847_000641"
     CDS             complement(45233..46006)
                     /locus_tag="VQ847_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3050024.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(46696..47568)
                     /gene="rsmA"
                     /locus_tag="VQ847_000642"
     CDS             complement(46696..47568)
                     /gene="rsmA"
                     /locus_tag="VQ847_000642"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3050025.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
BASE COUNT        14022 a        10594 c         8796 g        14312 t
ORIGIN      
        1 tatcaatcat gaactaggat tctagttttg caggaagtct attatatata tgcacagaca
       61 tatgaaatct ttttgataca gccttctttt tacatagaga gacagcagtt atgatatatt
      121 tatccattca caacatcttc tgtaccaata ctacaataat tggtacattt tgattacaca
      181 atcgtttcaa aaaatatgat ggaagactga gtattttata gtaattccct tcctatcaac
      241 tagatcaacc agttgagtgt tgaatgttga aacaccctag cctcagcaaa ggactatgat
      301 cagcatttcc tagccaatag gacgctccaa atcacctatt ctaagtccat cactagcttg
      361 gtcagtaaga tacagactgc aaggcaagac tgacgtggtt gatgagattt tggaagagta
      421 ttacaatcat agattcacca gtagacttga ccgcagattt aactatagta gattgaaact
      481 agaatagtac acttctgctt ctaaaacatt gttagaaatc gatttgactg tcctgatcaa
      541 tttgtcctgt tctcgtttca ttttactata ctaaaaaacc acctgaaaca aatcaagtga
      601 ctagaggata aaaacaaaga ctgggcaaaa agttttgaaa agcaaaaaac gcataatatc
      661 aggtcttgaa aaaccttgat actatacgtt tgattgtggg aagattgact tcattttctc
      721 ctgaaattga agttttttct agtttccagg tatagacgaa ttcaatatag ccatctcgct
      781 acaattattt taaccatcga aaaaattttt cagaatttca aaaatttcat tttgatctaa
      841 tgaaatgtca tcattttgaa gaatagttga cttcacaagc tctaattcta tcacaaagcg
      901 gtgcatgtct gcttttaccg cactacttga tgttatagcc gataactttt catctcctag
      961 caaggaagct gtcaaacggg taaggtcatt caaatgcttt ttaatggact tacttaaacc
     1021 ttgagcacct gtagcagagc gttccctcat atccagccaa gctttagcct taaaaataat
     1081 taatactcaa tgaaaatcaa agagcaaact aggaagctag ctgcaggctg ctcaaaacac
     1141 tgttttgagg ttgtagatgg aagctgacgt ggtttgaaga gattttcgaa gagtatagac
     1201 cacaattact caataccgaa tacccctgaa tggtttcttt ttcatgcacc aatatattat
     1261 aataatcttc atccaataat aaggctgata aactagcatc ttggtcaaaa tgtaagggaa
     1321 tttctcgacc gtccttcttt aatggatatt ctggtaagat actaaatagt tcaatcatag
     1381 aaggaaactc agaattagtt gttgtaaatc gaaaaagctg cgctttctca tctttctgac
     1441 ttccttgata ctctcccaat tctaaaaaat gattcaaggt agtataaaat tccttatttt
     1501 ttacttcatc aatgatgacc atatcataat cttttgttgt gcgactttta aatccttgcg
     1561 aatccaatac gatagaggta gcagttcccc caatcagaac ataatagttc tgaaaatccg
     1621 caaacatttc ttgaaaaata actttcgtat tagctggcat catcttctcc cagatactgt
     1681 aatatcatat tttctagtgc ttcactctct tcctctatac gtgggtcatc atcatctttt
     1741 aaggtcaaat aaagagaaat cggatctaca aattgtttat catgattatt tttaaaatca
     1801 ttccaaaact cagatacaaa aggacgatat ttccatatct ctagcatctt tcattttaaa
     1861 acatgctgag aaagtggcaa ggataactga ttgaattttc tctgccatat gacatagcta
     1921 gtattttcat ccgtttcagc taaaaaagtt gaatgcgaca aagcataagc accaccatat
     1981 agaaggttag aaacagattt tatctgcttt atatcgccat ctggcaataa aaaggcaatc
     2041 cacgttaatt gttcgctagg tattaattcc ttagggactt cagtatcatt cgcattcagt
     2101 actagtccca atgtagggaa gaagaggttt cccttaaagt ctacaaacgg aactctagct
     2161 tgaagtaatt gctttttttc accgtctgat aacttcgaaa acaccaaaac aacatccata
     2221 ttggctttat cacccatagt gcgagcctga gtaacaaatg aactcaaact cccccttctc
     2281 ttttctttaa tcaataaaaa tgattcctta tgaaaagtca tttgagtata ctcaaacttt
     2341 tttacaaaac tgattggtaa agtcaaagtc agttcctcaa tactgacatc aacataaaag
     2401 gattgaaaaa ttgacattat ctttttgaca ttcatgtttt ttccttattc tatcattttt
     2461 attatatttt atcattcggt ataataaaat ataagttttt tgataaaata accaaaaact
     2521 actcgctatc ccctctcaca ttaccctaca tatcgtttga catgcgactg atagttcagg
     2581 aaaacttcaa ggagaacttt tctctcatcc actatgcagg acttactatt tcacttctac
     2641 tcctataggc tcaatttgac atttttcttt ttcgaattgc tcatatgcct cctgaatagt
     2701 gagttcgatt tatccaaatt tatttttgtc tattttgatg aatacttcca cgaagaatga
     2761 atttgcacca attttccttc tctttttaag catattattc cagatatgat tgccctcttg
     2821 ttcagtaata aattacgctt taaacgcttc aatcagtata tctcctgttg tcatatgttc
     2881 taaagaaaat tcttctacat atggtttaac atctcttagg ttattacttc ctaatatccc
     2941 attatgcttt ttcgctaagg aaatagatgc cccttctcct ttaccaataa tcttgttact
     3001 atcatgattt cttgttaaat ctctatataa tgcgtattct tcagttccaa tgtctatgct
     3061 cacaatctca gctgaaccct tagctaccaa ctgatctatc ctagatttta aatggggaat
     3121 tgtaggtata ttgatttcat catacacctc ttgtggaata acaattttac ccaaatagag
     3181 cttttctaaa agatgttcaa tgccaaccca taaaaatact gaaatacaat ctgcatcaat
     3241 aaatacacga ctagtcaaac gacaactccc ccctcttcat ctagcccata tacaatatca
     3301 tatctgaaag catctagtaa cagttcctca tacttccctt gcgaaattct gttattttct
     3361 aaaagttgtt cagttgaatt aatatattat cctaatgcca tttctttttt actttctgac
     3421 aaaggacgat ataaacttgt atcatagcct aatcttgaag ctgtctctat aacactaata
     3481 tccatatttt taatttcttc tgcatcaagg tatccatcat tcctcaatct atataacata
     3541 gctttatgac tgataccata aaactgaccc aattttataa tatcttctac ttcaagatga
     3601 gttctattgg cattttctct gatttcctca accatcctat acagtgaaga tgggaaaatt
     3661 aaaaaataag aagcaaactg atccgctttt ctttcagttt catctccttc accaatcaag
     3721 ataagactga ctgaactctt cttcacctca tcataataaa gatgatacag tccatgtgct
     3781 aaagaaaatc tttacctttc taatggcatg tctgaattga ctgcaatgag actgaactga
     3841 gttcctttat aacagactcc gctaatattc tttccgagtc cataaaatac cagcgtcaaa
     3901 ttttctatct tttgtaccaa tttaaaaata tctatcggcg attcaccatc agctcccaac
     3961 ttttttctaa gatttgaagc tttattactt aaatccattc gtgatattcc tttcaccttt
     4021 ttccattttg gcaatcatgc tttgattcaa agacaaatac tcagcaatct tatcttgagt
     4081 aagatttgaa gatattctaa gttcttttat tctttttcca acatcacata catttatcac
     4141 atacatttat catattcata cacctctcat aaaaagaata gcacactctt gtcataattt
     4201 tttaaataaa aaaattatga caaaacaagg aagcaattta ttgatgctgc ttaaaaatct
     4261 aaaattgatg agttcctatc aaaaatcgta tcttcaacct caaaacagta cttaaagcta
     4321 tccgactcgg tttacattgt caaatttaga ttttatttga gcataacttt ctagtttgct
     4381 ttctgatttt tgtttaatat agtagcaaac attgaaggaa atatctccac aaaaaaacgc
     4441 atactattaa gctttttcaa gacctaataa tatgcgctgt tctgatttga aagacattcc
     4501 attattattt tactgtaatc aagccatctg gctctactgt gaattctggc ttgtctgcca
     4561 gtgttccgtc tggtttgagg tagtaccagc ctgttccgtc cgctgactgg ataaaggcat
     4621 ttgataccat ggcgccttct ttagcgtcta agtagtacca agtgtccttg tacttgaccc
     4681 agcctgtctt catggcacct tcttcgttga aatagtacca cttatcagcg attttcttcc
     4741 agcctgtagc catttcgcct gagttgtcga accagtacca gttgccgtct gtgtgcttcc
     4801 tccagcggtc tgcaagcata tagcctgaac tgtcaaagta gtaccaagtg ccattgattt
     4861 tctcaaactt gtcttttgga taagagccgt ctgaatgtac gtaccagtag ccagtgtcat
     4921 tcttctgcca gcctgtttca atcgtcaagc cgttctcaat atcatactta aactgctcac
     4981 ggctaatgcc ccattttgcc aagtaagggt atggatccac atggtctgag tggttgtttg
     5041 gttggttatt cgtgcaatac tcgtgcgttt taattccagc taaactccct gtatcaagcg
     5101 ttttcggcaa acctgcttca tctgctagat tgcgtaagag ttcgatataa aggcggtaat
     5161 ccgtcatgaa ctcttcttta gttgaatggc tttcaatcag ttcaaccgct gcataggtct
     5221 cagcattcca accgccccca acgtcccagg caccattatc aacaggtcct acctgcatga
     5281 tgcaaccgtt cccaacaatg tgcgagaaaa aacctaattc tgggtctttc cgccagtgat
     5341 aatccgcttc attctgtacg gttgaatgcg gattcccagt tgagtgtgcg tgtacttgcc
     5401 tatatggttg cacgccgact tgaggcaaat ctgttcttaa tttactcaca ttaatttcca
     5461 tattctactc cttatcaatt aaaacaactc attttttaca atccagaacc agaaactcct
     5521 ttatttctac cttacaaaga agacaatctt agtcacgatt aggcttgtag atagaacctc
     5581 aaaacgcact attttgacac tgtaaatagg actgacaagg tctgcattct atctacaata
     5641 acaccccaga ctaaaaagct tttcaaaagt atatttttac agtctctata tgtccttttc
     5701 ataaatacta tactttatta tatcatataa aagaagtcaa aagtctgtta aactattttc
     5761 aacaccaaac taaagaagag aacacaagtt ttttcgatgt tcactagagg aaatggattt
     5821 tattcagtaa atccaactag gattgcactt tggttgccaa aattgccttt ccttctttta
     5881 tcaagggatg acggaatagt gagaagtaca gttgaactgt catggcaacc cagataagag
     5941 gttcacaaag gataacaccc ttatatcctg cccaaggaat aatcaaaacc acaaaaacga
     6001 tttttccgat tagttcaata aagctagaaa ctagaggaag gatcttctgc cccaagccct
     6061 gcaagcaatt gcgataaatc aacaagaggc tcaaaatggg ataaaaggct gaactgattt
     6121 gcagatagag acttccattt tctatcaagt aaccatctgt cgaactagcc aagaaggaaa
     6181 ccaaggctgg actggcaaaa aagaggaaaa tacaaacaaa aactgcccag gatatactta
     6241 aacgactgcc gattcgaaga ccttgaacaa tgcggtcagg tcgcttagct cctagattct
     6301 gagaagcaaa ggtcgtcatt gatgcagaaa tagcggtcat aggaagaagg gcaaaggtca
     6361 taatgcgtcg agctgccgtc tgggcactaa taatcactgc accaaatgta ttaacagaaa
     6421 actgtaaaat cacactgccg atagatacaa ttgaactcat caagcccata gccaaacctt
     6481 gctccaagag atccgcgtac aagcttttgt cccatttgaa atgtttaaac cgtggcaaga
     6541 gttctggcac acttttacga atataataaa agcagagaac cgctgataaa ccttgcgaaa
     6601 taatggtagc aagtcctgcg gattgaactc ccagatgcaa ttgcgtaata aaatagagat
     6661 ccagaaccac attaaccaag gcagagaaaa tcagaaatcc cagggctgct agactgtcac
     6721 caatagaccg caacaagcct gcaaaaagat tataagcaaa gctgacacct acacaggtca
     6781 caatcataga aatatattga taagattgag gaagaatttc tgcaggagta tctaagtatt
     6841 gcaagagagg atacaagcca agaaagccca gcaacataac tagaatgctc aaaagagcac
     6901 ctaaaatcca ggtggctgct actgcttcct tgattttagt gaaattccga gccccataat
     6961 aacgagcaat gacaatcccc atgccattgc caacaccaag tgtaaaacct acaatcaggt
     7021 caaaaatcgc tgtcgtcgct cctactgcag ccaaggattc ttgaccaaga aatcgtccaa
     7081 caatcaagac atcagcagtg ttatagagct gttgaaaaat atttgatagc aagattggaa
     7141 aggtgaagct taagagcgag ggaagaatcg aaccatgtat caggtccact gttcgttttt
     7201 tattcataaa gctattatat cagctttcca gaggagcgac aagaaacagc aaacttatat
     7261 atagcggaat gaaataagga cagtcaaatc gatttttaac aatgttttag aaatagatgt
     7321 gtactattct agtttcgatc tattatagtt ggttgagttt ggaatagtac gctgtagctg
     7381 ctaaaacatt tctagaaatt aatttgactt tcctaataaa gttgttcata tcttatttca
     7441 agctactata tataatctaa aaacttgaat caaaaatcga aaaagtagcg gatttttcca
     7501 ctgctttaac agcttattct tcaatttcga tttcaagttc atcgcctaag tcaagcgtaa
     7561 cttcttcatt cactgcttct tctttctttg gctcatcttt tttgttttca gtatcttgtt
     7621 ctgaaacttc ttctccatca atcaagccaa atttagaacg gacttgctta tcaatttcat
     7681 caaagatttc tgggtgctct gccaagtatt tcttagcatt ctcagaacct tgcccaattt
     7741 tttcatcttt gtaagaatac caagcccctg cttttttgat aatatccaaa tcgcttgcaa
     7801 tcttcaaaag ctcaccagtc ttagaaattc cttctccgta cataatttca actacggctt
     7861 ccttaaacgg tggagctacc ttatttttta caaccttaat cttagtttct ttaccgacat
     7921 tggtttcttt ttggtcacca gttcccttaa tttgtgtatt accacgaaca tccaagcgga
     7981 ctgaagcata gaatttcaaa gcacgtccgc ccggtgttgt ttctggattt ccaaacatca
     8041 ctccaacttt ttcacgcaat tggttgataa aaatggcaat tgttttggtt ttattgatag
     8101 aggcgccaag tttacgcatg gcctggctca tcatacgagc ctgcaaacca acatggctat
     8161 ctccgatatc tccatcaatt tccgcacgag gaacaagggc agcaactgag tcgactacga
     8221 caagatcaac tgcacctgag tcaatcaatt ttcccgcaat ttcaagacct tgctctcctg
     8281 agtctggttg agacaagagc aattcgtcaa tattgacacc aagggccgca gcataagctg
     8341 gatcaagggc atgttccgca tcgataaagg cagcaatccc accttctttt tgcgcttgtg
     8401 caactgcatg aagggcaacc gttgtcttac cagatgactc tgggccatag atttcgatga
     8461 tacgtccctt aggataacca cctgagccaa gggcaatgtc aagagctaaa gaacctgagc
     8521 tcatcacttg caccttttgc tccgcacgtt cacccaaacg catgattgat cctttaccaa
     8581 agtctttctc aatcaattta agagcgtcat tcaaggcctt ttcacgttct gccccaaatt
     8641 tttttgaaat ttcttctaat ttttttggtt ttttcgccat tctattctcc tacattctaa
     8701 tgatcctcag acctatctac tattatatca aaagttagtc acttaataaa gccttgcgaa
     8761 ctaggttaaa ggcatgcata accgcaatat gacgtacatc tgctcggctt ctgcctccaa
     8821 tattaacctt gataacctca gttccttgct cttgcgccaa gcctatgaag actgtcccaa
     8881 ctgggtgtcc ttctaggcta tctggtcctg ccactccggt caaactaatt ccaaaatcag
     8941 actgggtctt gcttcgtgcc tgctcagcca tcttctgagc tgtaaattca gacaccacac
     9001 catgttcttc caaattcttg gcaggaatat ccaacatcct tgatttttcc tccaagctat
     9061 aggtcacaaa accaccctta aatatacttg aaactccaga aaaattcgcc acggtagctt
     9121 ggaaaagacc tgccgtcaaa ctctctgcag ccgcgatggt tttcccttgc cttttcagtt
     9181 cttctaccac aatgctggct aaactagttt cttccccata accatagcaa aagtctcgta
     9241 aagaaattcc ttcgaaagtc tggcagtcca agatttgatt ttccaagata tccagcgctt
     9301 gattcgcctc ttcttgactg ctagcctttg ttgacagacg tagagtgact tctcctgtct
     9361 tggcataagg ggccaaggta ggatcgatct gattatcaat taaatcagcc aaaatcgtaa
     9421 ccagctggct ctcgccaatc ccaaagaaac gaagaactcg ggaatacagc ttgctccctg
     9481 tcatcaactt gggtagaagt tggtttaaga ccatgggttt caattcactt ggcggacctg
     9541 gaaggacgac ataggtcact ccgtctactt ctaattttcc tccaacagcc agtcctgttt
     9601 cgtttggcag tggaatcgct ccttctacaa tttgagcttg tctttcgtta ttcggtgttc
     9661 gggcatagtc tggtcgcagg gcaaaaaaga tatccaactt ctcctgagcc tgaggatcaa
     9721 agactaatgc tttccctaaa aatttagcta gggtttgttt ggttaggtcg tcctcagttg
     9781 gccccaaacc gcctgtcaaa atcaccagac tgctacgttg actggcaatc tcaagcaaag
     9841 acaagagacg aacttcattg tctcctacag ccgtctgaaa atatacatct accccaatct
     9901 cagctagttt ttccgacaaa aactgggcat tggtgttgac aatctgtcct gtcaaaatct
     9961 ctgttccaac agcaatgatt tctgctttca tgtttcctcc tacctatcta ttcgtatttt
    10021 tttgaaaaaa tcgcaggaat tttcctacga ttgatttttt tatttgtatc aaaagttaat
    10081 tatcttcatc accaacaggt gctctgccaa ataaatcttc aaataaaacc gcattggttt
    10141 caagctgagt aacttcttct tgtcccaaag aacgtcggag tatattttgc atttccaaca
    10201 tatgtgctct cgaaacaatc tggtaagaaa caccttgaag tatctctcct tcaccctgca
    10261 actgctgagt ttcaatggtt ttaaatgaat ctttatagcc tagcaagtta gggatacttt
    10321 ttgcagacaa atcaatattg gtctgcatat tgtcactcaa agcttttaga atctcttgat
    10381 aatgaccaat gctatttaaa ctgagagctt tttccatgac tttttgaata acttcacgtt
    10441 gacgtttttg acgaccataa tccccctcag gatcttggta acgcattcgt gcatagacta
    10501 gggcttcttc tcccccaata tgttgctccc caacaccgat agaaatggta ttaaattctt
    10561 cttggtcact gatagaaatt gggaaaccta ggatattatt gactgtaata cctcctactg
    10621 catccactaa tttttgcaac cctctcatat tgaccatcac atagcgatca atatggatat
    10681 tcatcatttt ttgaatggtt tctatagcaa gctctgctcc accatctgca tatgctgagt
    10741 tcagtttcgc ttcatgagcc tgaccattcc ctgattcaat gcgcgtcaga atatcccgct
    10801 ctaaactcat cattgttgtt tttttcgttt taggattcac tgtcatcaag atcatgctat
    10861 cacttctacc gacccaagtt tcagttcgtt caacatttcc ggtgtccact cccattaaca
    10921 gaatggttag aggttcagtc gcttcaataa ccttggtttc ttcgccgatt tttttatagg
    10981 ttttagctaa ggtttctgtc ccttgttgat aaatagtata agcaaaaaca cctactccta
    11041 ctacagttac agaaagtaaa gctagcacca ttccaataat ttttttaacc atatttctac
    11101 taacctatca gtttacccat caagtaaaca tcgataaatt tcccttcttc tatatatgcc
    11161 ccacgctctt ggctaccttc aatgacaaag ccatgctttt gataaagatg gactgctgct
    11221 tgattacgag tttggacagt cagttggaga cgacgcagaa tgccacttgc ttgtgcccac
    11281 tctatcgctt cttctagcaa caaacttccc aagccattat tccaatatct ttttccaatc
    11341 acaatgaaga gatctccaat atgacggact ctcttacgct gatcagctgt aatatttaca
    11401 ataccagtaa ttttgccatt taagaatgca agtaaggtta tctgattgtc cgaactagct
    11461 tgcttgttga ggaatatttc catctcctca ctagtcaaga gaataccatc tccgtctagg
    11521 ctggtaaagt ctgtctccaa actcacacga tttaaaaagg ccactaattc agctgcatct
    11581 ttgggctctg cttccctaat gagcaattca tactccatat tgaagctcct ctgacaattt
    11641 ctcagcacgc aaaccctttg cctgaaaatt taaacggcgt ccatctgctt cttttagaat
    11701 ttccaattct aaataagcat ctggcaaggc atctcctaag agatttcccc actcaataac
    11761 agtcacgccg ccaccaaaga taaactcatc caagtcgata gaatcagcat ctccttcaat
    11821 acgataaaca tctaggtgat aaagtggaag tcgaccttca tactctctca cgatagtata
    11881 ggtaggactt ttaatcattt gagaaatctg taatcctttt gcaagtcctt tagtaaaggt
    11941 cgttttacct gcacccagtt ctccaattaa gattaaaaca tcattctttg ctaatagatg
    12001 gcccaaacgc tcccctaagg cttgcaactc ttcttcattt tttatgtaca tactcttatt
    12061 ataccaaaaa cttttctttt gtgtctattt tcctactaaa cttatcatca taacatccat
    12121 aaaaaacagg ctttctctaa aagaaaatga gcgtaacaat gaccaataca agatctcgga
    12181 aaatatgacc ataaaaggaa acttccttct taaccgaatt tgggacaaga taggctgcaa
    12241 aaaacaagcc cagtccaata taaatcagaa gtgagacaat ggtcattgga tttcttaaga
    12301 aaagaagtgt tgctaaaata gtcaccaaca ctgtcttttt tctgtccagc atagcaagaa
    12361 aatcgcgcac gtattttttc aagggtaaaa aaatcagcaa atctagccca aataggaaaa
    12421 agaaggatgg caataaaaag tcaactaatt cttgctgcag cgtatttttg atgaacaagt
    12481 tatctgacaa aacaagaaca gctcctaaca aattaattaa gagtaacata ctgtaaaaaa
    12541 gcttcaccga cttcttactg gctaggacac tatggacttc ttgcttacga gtataaagat
    12601 aatttactcc agcacagatt cctgaaacga aaaccatgct tccgatgaaa aaagctgtac
    12661 tttgtttaaa ggacaagatg cattccttcc ataggaaaca gctactcaaa ctgatttgaa
    12721 ttaaagctaa caaaaataag attctcattg atttcatctt ctctctccct tcctaccaat
    12781 cattatacta ggagaaaaga gagaactgtt tctaatcttc tcaaatgtct ctttaagacg
    12841 ctaaacaaac actagagact aatactcaat gaaaatcaaa gagcaaacta ggtagctagc
    12901 cacaggttgc tcaaaacact gttttgagat tgcagataga gctgacgtgg tttgaagaga
    12961 tttacgaaga atataaattt gaaatcatga aaatccgtca aacgggtggt tgttttgtct
    13021 cgcacctcac ggagcgagac ggactcagag tcacataatt ataaggctga tagtattaat
    13081 ctaactatca gccttacagg ttatttaacg tttcagaaaa actataatgt caagattaac
    13141 taaacagtat ctagttcctt caaataattt tctatcttca tcaacattaa aggattgtta
    13201 taaatcttac ataactctct tgcttctata taataatttt tgacttgttc tctgtctaga
    13261 aatttggctc cagcatttcc tacaagaata agtagaggag ccaattggta gcttgtctgt
    13321 ctttgtttac agagttcaat cgtttcaaga gcttcttgga tggcttcatt atatttttcc
    13381 tttgatacta ggtagtgagc gtagttgtaa cgaactctga tgtagccaaa taaaaactct
    13441 tgatggtcca aattttttgt ctgatacaac tctattaaat gagagtagtt tgcctcatat
    13501 tcttgttcac gacccactaa ggaatagaaa ttagatagag tattcaacgc ctttaaataa
    13561 atcagagtat ttgaagagac ttttaataat atattttcca atgaagaaat tgcctcacac
    13621 ttactgtcat attgatagaa gtcaataata gctttaatcc attcaaggta agttcggtct
    13681 tctagtgtta gaaaagtact tcgttcaatc tctattctat aaatatattc caaatcgtca
    13741 taatttctat cgtctaatag tcgagcagac aattgcttga aattagagag gttagattta
    13801 atttcaattt gttcattaaa aaaataatct aatggtactt caagtcgttg agagagtttg
    13861 aacaaaaggt ctgcggaggg aatgaaatgc cctctctcaa ttttactaat ctgactttgt
    13921 tcacaaattc cttctgcaag agtttgttgg gagagtctca actcttttct tttcaatctg
    13981 aatttctctg cgagtgtatt cattaaagat aataaacctt cctatttgct taattgcatt
    14041 ataaaatttt tagttcaaaa tagcaagtta aaagaataaa taattcttta tggtaataaa
    14101 ctaaaaaaag tcaaaaatta cataaaaatg cttgaccgaa taatatatat atattaaaat
    14161 aaaaacaagg aaaaagaaaa gggtttcacg aatgaagaaa aatcgtggaa ttcaaaaatt
    14221 agctatatta gtattactag gtgtttttat gcttagtaac acaattcctt accaacagtt
    14281 tattcagaag aatagacaat tggagattcg agtccaatca caaaagaagt ccaatggtct
    14341 tgatgttggg aaggctgatt gatttcgtat tactttaaaa ttcaactatt tagagaaagg
    14401 tattctgatg agagcttgta acaataccag atagatatta gtaagcttgt tagtttatag
    14461 agggcagggg tatttctgcc ctctgtttta gaataaggaa tgcactatga aaaaattatt
    14521 tatactcata tccaacctgc ttgctagttt gttctttgtt tgggtattta ccatttggac
    14581 tgatacatat gtctcctatt attaccccaa cgttgttgta catgattctt cccctgaaac
    14641 aacttttcag catgttgcta cacgcttgga aaaactagca gaagaaacag atagctttat
    14701 tgcgattcaa caccaagatt ctaactcaga aggtactaca gttttttctt atacgacctt
    14761 tggggacgga aagttgcctg atgggcttca ggaaaaaaaa ctagaagatg ctcaaagtag
    14821 tagtgttgaa acaaactatt ttgtattcga tggacaccta gatattcact tgctaaggga
    14881 ggagctaagt caacttggct tgactaacat gaacctgaca attccatcta aactatctac
    14941 gttaatggct atctttagta acggatttca gttaatcagt ctattgattt tcatcttaac
    15001 ctttgtagca ctgactttaa ttagtcaaat tagccaatta cggtcgtcgg gcattcgcct
    15061 catttcagga gagaaacggt ggtccatttt ccttagacca gttggtgagg atttgaaagg
    15121 gatagctgtt ggtttcagtt tagctggcgt gctcgccatt cttatgcaaa aaattctgtc
    15181 gcttccaacg caatccctaa tgaccatagg agcaggcttg ctcagttata atctcatctt
    15241 gttgtcgatc tccctgtttt tcgctcaact cttcgcagtt gggataaaaa agatacacct
    15301 gatgcagatt ataaaagggc aagtgcctgt cagaggaatc attagtttga ttttaatcgg
    15361 tcaactatta gcgattatta ttgtaacgct gggaataggg agtagcttaa agtattccca
    15421 agcctggcaa cagcatcgga ttggacaaga ggcttggagt caggaaaggc aactgattac
    15481 cctatcaatc agccgtgaag gaacgagtcc tggttttgat gaacaagctc aaaggaaact
    15541 cagaacttgg tatcaattga tggatctggc tgtttcagaa caaaaggctt tcttatctag
    15601 acaccagtta attgaccgta ctttgcaaaa tggcatggct tcctccaaaa acttgataac
    15661 ctctacagaa tggcacgatt acaacccgaa tggcaatgtc cttatcgtca caccgcaata
    15721 cttggagcgt caaaacattc ctgtagatac aactattgag caaaagatga atcaccttta
    15781 tgtaggggag tttgtcttat tgctgcctga acacctccgt tcagaggaag aacattataa
    15841 atctgttttt gaagacgact taaccagtcg catgtctagt caagatgaac gacagcaaat
    15901 gactgctacg gtaggttatt tagaatcagg tcaggatcgt tttgtgtata atacgacccc
    15961 tatttcttac cagcagtttt tgaaagatcc aatcatcatt gttataacac cccaatcaac
    16021 tggtccacag tccattttgt tttggataga cgcagtacag aactacgttc tctttaatca
    16081 attgtctgat gcccaggagc ttatccagag acaaggcatt gaaaattggg tctcagaaat
    16141 gcaaacaggt taccacaact acatcacatt attggataat attcagaggg aacgttgggt
    16201 aatgctagca ggagctgggc ttgggattgc aacttcaatc ttgttgttta acactatgaa
    16261 taggctctac tttgaagaat ttagacgtgc catttttatc aaacgcattg caggtctcag
    16321 gttcttagaa atccatcgca cttatctctt tgctcaactg ggtgtgtttt tactgggatt
    16381 tgttgcgagt gtatttcttc aggtagagat aggagttgct ttcttagtct tgttactctt
    16441 tactggtcta tctcttttac agttacatgt ccaaatgcag aaagaaaaca agatgtccat
    16501 gcttgttttg aagggaggtt aatatgattg aacttaaaca ggtgagtaaa tcttttggag
    16561 aacgagagtt attttcgaat ctttcaatga catttgaggc tggaaaagtc tatgccttaa
    16621 ttggttcaag tggtagcgga aaaacaacct tgatgaacat gattgggaaa ttagaacctt
    16681 atgatgggac gattttttac cgaggtaaag acttggccaa ttataaatcg agtgattttt
    16741 tccgtcacga attgggctac ctcttccaga actttggctt aattgaaaac caaagtattg
    16801 aagaaaacct taagctaggt ctcattggtc aaaagttgag tcggtcggaa cagcggttga
    16861 ggcagaagca ggctttagaa caggtcggcc tgacttatct tgacctagat aagcgcatct
    16921 ttgagttatc gggcggagaa tcgcaacggg ttgccttggc aaaagttatc ttaaagaatc
    16981 caccctttat tctggcagat gagccaacag cttcaataga cccagcaact tctcagttga
    17041 ttatggagat tttgctatct cttcgagatg ataataggct aatcattatc gcaacacata
    17101 atccagcaat ttgggagatg gctgatgaag tgttcacgat ggatcgtctg aaataaaaat
    17161 ccttgttttt aattgcacga tgagttactg aaatattatc atgaatcaat aattggagtt
    17221 aatttagaat tgtactttat taatattgag gtaacttttt cttgataaag gaagaaatag
    17281 tggagaggaa gttagaatga aaaaattcga caattatatt gttgagaagc cttgcgattc
    17341 taattcagat aaactgcaaa aaatcttaat aattgaaaat ttggtagatg atattttgca
    17401 atttcctctc agaatcaata atagtgtagg agagattttc ctcctacaac cgtttcaaaa
    17461 gaaaactatc tttattccat gttattttga ggaagatatt gtgaaagtca aagatgatga
    17521 taaagttgag tggaatttgt tagaatttca aaaatttaga gcatttttgg cttagtaatc
    17581 tgtgttgaag gctcaaaacc tatggtaaaa aagtcgcttt gaaaacgtat tgcctccaaa
    17641 gatttagtta aataatgatt taacacaaaa agaaattatt gaagttctgg aaagatgttg
    17701 tttcagtatt gagaaaaggt gggaaaaact tgcgattttc acagagaaag gaagaaaaag
    17761 tatagaaata tagtcaattg aaacaagaac aggacaaaag aaccttttgt gccatatttt
    17821 tctcctttcg ctttacaatt ggcttgaaca cctttattgt atcgcgtttg gagttttttt
    17881 ggtataacct tcgacgcgca cccgcatagc gggtgttttt ttgtctcgca cctaacggag
    17941 cgagacgaac taatagtcac ttaatcaaaa aacgcaccat atcaaaaact aaaaagtttg
    18001 atatcatgcg tcatgtctta aactaattga ctatactttc tattcaaatg agcttttaac
    18061 caattgattg agccaatcca ctcttaaaac caaagagcaa tttctcgctt agctgactct
    18121 tctgaatctg aaccatgtac aacattttgg ataacctcat tttctccagc agcttttgca
    18181 aaatcacctc gaatagtgcc tggtaaagct tcttctggac gagttgcacc catcatggtc
    18241 cgccaagttt cgattacttt gggaccagaa atgacaccca caagaactgg acctgaagtc
    18301 atgaattcac gaatcggtgg gtaaaaactc tgaccaacca agtcctgata gtgctggtca
    18361 atcaactctt ctgaaacttg tgaacgaaac tccaattttt cgattgtaaa tccacgttgt
    18421 tcgatgcgct ttaacacttc acccactagc cctcttttta caccatctgg tttgatgata
    18481 aagaatgttt gttccatacc cgtctccttt gtcagcttct ttcttttatt ttaccacatt
    18541 tcgtggaaaa atggagaaag ttttcagaat agagaatgag agaacccgag ggttctctca
    18601 ttctctatta ttctactgtt tcttccacag tttcaacggc agtatccaca actacttctg
    18661 ttgtttcttc atttccttct tcctctactg gaggattaag gtattcttct tcgttgacag
    18721 catatggttc aaggttacgg taacgggcca taccagtacc agctgggatg atcttaccga
    18781 tgataacatt ttctttaagt ccaaggagat ggtctttctt accacggata gctgcgtcag
    18841 taaggacacg agttgtttcc tggaaggaag ccgctgacaa gaaactgttt gtttcaagtg
    18901 aggctttggt aattcccata aggactgggc gacctgtcgc tggaactcca cctgcgataa
    18961 ggacatcttt gttggcatct gtaaagtcat tgatatccat gagggtaccc atgagaagat
    19021 ctgtatcacc tggatccatg acacggactt tacggatcat ttgacgaacc attacctcga
    19081 tgtgtttgtc accgatttct accccttggc tacggtaaac tttttgtact tcaccgagaa
    19141 ggtacgtttc aactgacaag acatcacgaa ctgcaaggag acgttttggt tggatagaac
    19201 cttctgtcag agcagcacca cgcgctactt ggcccccaac ttcgacacgc atacgagctg
    19261 taaatggaac gacatattca ccttcgccag tttcaccctt aacaaagact ttcttggtac
    19321 gagttgatgc atcttcttcg atagcagtaa cttgtccttt aacctctgtg ataaccgctt
    19381 cccctttagg attgcgggct tcaaagattt cttggacacg aggaagaccc tgagtgatat
    19441 cggtatttga ggcaacccca cctgtgtgga aggtacgcat tgtaagctgt gtaccaggtt
    19501 ccccgataga ttgggcagca atggtaccaa ctgcttcacc aacttcaacc gcatcaccag
    19561 tcgccaagtt gataccgtaa cagtgacggc agacaccgtg acgagtgtta catgtaaata
    19621 cagaacggat agtcacttct tccacaccag cattgacaat ttcacgcgcc ttgtcttctg
    19681 taatcaattc atttggacca ataatcactg caccagtttc tggatgttta acagttttct
    19741 tagtgtaacg accgttgaga cgctcttcga gagactcgat catctctttt ccttctgcga
    19801 tagaacggat caagagacca cggtcagttc cacagtcgtc ctcacggatg ataacgtctt
    19861 gggcaacgtc gaccaaacga cgagtcaagt aacctgagtc ggctgtctta agggccgtat
    19921 cggtcatacc tttacgagca ccgtgagttg agaagaacat ttccaatacc gacaaacctt
    19981 cgcggaagtt tgaaaggatt ggcaattcca tgatacgtcc attcggagca gccatcagac
    20041 cacgcatacc ggcaagctgt gagaagtttg agatgttacc acgggctcca gagtccatca
    20101 tcataacgat tgggttctta ggatcttggt tagcaatcaa gcgtttctca agtttttcac
    20161 gggcagcacg ccattcagct gtaacagcat tgtaacgctc gtcgtctgtg atcataccac
    20221 gacggaattg tttggtgatt tgttcgacac gtttgtgtga ttcttcaatg atttcagtct
    20281 tgtcatcaac gactgggata tcggcaatac ccactgtcaa tcctgcaaga gttgagtggt
    20341 ggtaaccgag gttcttcatg cggtcaagta gggcagaagt ttctgtcgta cggaaacgtt
    20401 tgaagatttc agcgatgata tttccaaggt ttttcttctt gaatggaggg ttgagctcaa
    20461 gattgctgat agcttccttg atatctccac caagtggcaa gaagtattta gctggaacac
    20521 cttctgtcaa gttggcattg tttggttctt gcaagtatgg tagcccctct ggcatgatat
    20581 cgttgaagag aattttacca actgttgtaa gcaagacctt atgtctttgc tcttctgtcc
    20641 aaggcttgtt gaggctgtct gttgcgatac caacacgtga gtggaggtga acataaccat
    20701 tgcggtaagc cataaccgct tcgtcacggt ctttgaagac cattccttca ccttcgcgac
    20761 cagcttcttc catggtcaag tagtagttac ccaaaaccat gtcctgagat ggagtaacta
    20821 ccggtttccc atctttcggg ttcaagatgt gctcagcagc tagcatgagg atacgagctt
    20881 ctgcttgtgc ttcttctgaa agtggtacgt ggatggccat ttggtccccg tcaaagtcgg
    20941 cattgtaggc ttcacagaca agtgggtgca agcgaagagc cttaccatca attaagactg
    21001 gctcgaaggc ttggataccc aaacggtgaa gggtcggtgc gcggttcaaa agcactgggt
    21061 gttctttaat cacttcttca aggatatccc agatacgctc atctccgcgt tccaccaagc
    21121 gtttagctgc tttgacgttt tgcacgatat cacgggcaac gatttcacgc atgacaaatg
    21181 gtttaaagag ttcaatcgcc atttcacgtg gcacaccaca ttggtacatc ttaagagttg
    21241 gaccaacggc gataacggaa cgtcctgaga agtcaacacg tttaccgagc aagttttgac
    21301 ggaagcgtcc ttgtttacct ttaagcatgt ggctcaatga tttcaatgga cggctacctg
    21361 gtcctgtgat tggacgacca cgacgaccat tgtcaatcaa agcgtcaact gcttcttgaa
    21421 gcatacgttt ctcattttga acgatgatac ctggtgcatt taactcaagc aaacgagcca
    21481 aacggttgtt acggttgata acacggcggt aaaggtcatt caagtcagat gaggcaaaac
    21541 ggccaccatc caactgcaac attggacgaa gatctggtgg gataaccgga aggatgttaa
    21601 gaatcatcca ttcaggtttg tttccagact tgtaaaaggc atccaaaaca tccaaacgac
    21661 ggatggcttt gacacgtttt tgtccagtag ctgttttcaa ttcttctttg agttcagcaa
    21721 tttctttttc aagatctact tgcttcaaaa ggtcttggat ggcttccgca cccatcttgg
    21781 caacaaatga accataacca tattcgcgca agcgctctcg gtattcgcgc tctgtcatga
    21841 tagacttgtg ctcaagtggt gtatccttag gatcaatcac cacataagcc gcaaagtaga
    21901 taacttcctc gagggcacga gggctcatat caagggtcaa gcccatacgg cttggaatcc
    21961 ccttgaagta ccagatgtga gatacaggag ctttcaattc gatatgtccc atacgctcac
    22021 gacgaacttt cgtacgcgtt acttcaaccc cacagcggtc acaaacaatt cctctgtaac
    22081 gaatgcgttt gtacttacca caagcacatt cccagtcttt tgtaggacca aagatcactt
    22141 catcaaagag tccttcacgt tctggtttca aggtacgata attgattgtt tcaggttttt
    22201 tgacttctcc ataagaccat gaacggactt tacttggaga agctagggtg atttgcatac
    22261 ttttaaaacg atttacatca accactattt cttccctttc tattctaagt gaactgctta
    22321 ttcttgttca gcagcttctt ctgttgcttc cgcttttgtt gctttctcag cttcttcagc
    22381 ttcaaaggct gctttagcct cttgggctgc tttttcgcgg gctttttcaa ggtcatctac
    22441 gtggatgaca tcttcgtcca ttccttcatc caagtcgcga agttccactt cttggtcatc
    22501 ttcgtctagg acacgcatgt caagaccaag agattgcaat tctttgacaa gaactcggaa
    22561 ggattctgga acacctggtt ttggaattgg tttgcctttt gtaatagctt cataggcttt
    22621 caaacgtccg ttgatatcgt ccgacttgta agtcaagatt tcttgaagga catttgacgc
    22681 accgtaggct tcaagagccc aaacctccat ctcaccgaaa cgttgtccac caaactgagc
    22741 cttacctccg agtggttgtt gggtaacagt tgagtatggt ccgactgaac gcgcgtgcaa
    22801 tttatcatca accatgtggt ggagtttgat catgtacatg actccgacag aaacacggtt
    22861 atcaaacggt tcaccagtac gtccatcgta aaggatcgtt ttggcatcgc tatccatacc
    22921 tgcttcttta acagttgacc aaagatcttc agaacttgct ccatcaaaga ctggtgtcgc
    22981 gatgtgaata ccaagagtac gagctgccat accaaggtga agctccataa cctgaccgat
    23041 attcatacgt gatggtaccc caagtgggtt caacatgatg tcgactggag ttccgtctgg
    23101 aaggtaaggc atgtcttcta caggaacgat acgagagaca acccctttgt ttccgtgacg
    23161 tccggccatt ttatctccga ccttaatctt acgtttttga gcgatgtaaa cacgaaccaa
    23221 catgttaaca cctgattgca actcatctcc atttacacgt gtaaagatct taacatcacg
    23281 aacgacacca tcggcaccgt gtggtacacg aagagaagta tcacgcactt cacgagactt
    23341 gtctccaaag atagcgtgca agagacgttc ttcagctgaa agatctttct cacccttagg
    23401 tgttacttta cctacaagaa tatcaccttc tttaacctca gcaccaatac ggataatccc
    23461 catttcgtca aggtctttga gggcatcttc accaacgttt ggaatttcgc gagtgatttc
    23521 ttcaggccca agctttgtat cgcgcgtttc tgattcgtat tcttcaaggt gaacagatgt
    23581 gtagacatcg tccttcacca agcgttcgct catgataacg gcatcctcga agttgtaacc
    23641 ttcccaagtc atgtaggcaa cgattgggtt ttgtccaagc gccatttctc cattttccat
    23701 agaaggtccg tcagcgatga aatcgccttt ttcaacgaca tcaccaactt ttacgagagt
    23761 gcgttggttg taagcagtac ctgagtttga acgacggaat ttttggatgt ggtaaacatc
    23821 caatgaacca tcttcacgac gaacttctac cttgtcagca tctgcgtaag taactttacc
    23881 atcatactga gcaatcacag ccgcaccaga atcgtgggct gcttggtatt ccataccagt
    23941 accaacgtaa ggtgcctgag gattaatcaa tggcacagcc tgacgttgca tattggctcc
    24001 catgagggca cggttggagt catcgttttc caagaaagga atacatgctg tcgcaacggc
    24061 aactacctgt tttggtgaaa cgtccatgta gtcaacaata ttagctggat actcttggtt
    24121 gaccccttgg tgacgtccca tgacaatctt ctcagcaaag gttccatctt cattcagacg
    24181 agagttagcc tgagctacag tatattcatc ttcttcatca gctgtcaacc aaacaatttc
    24241 gttcgtgaca acacctgttt cacggtcaac cttacggtat ggtgtttgaa caaaaccata
    24301 tttgttcaag tgtccgtaag atgacaagtt attgatcaaa ccgatgttag gtccttcagg
    24361 tgtctcgatt ggacacatac gaccatagtg agtgtagtgc acgtcacgta cttcatatcc
    24421 ggcacggtca cgagtcaaac caccaggtcc taaggctgac aaacggcgtt tgtgagacaa
    24481 ctcagaaagc gggttgtgtt ggtccatgaa ctgtgacaac tgtgatgaac caaagaattc
    24541 tttaactgca gctgttacag gacggatatt gataatttgt tgtggtgtca agacttcatt
    24601 gtcctgaaca gacatacgtt cacggacatt acgttccata cgagaaagtc ccaaacgtac
    24661 ttggttggca agcaattcac caaccgcacg gatacgacga tttccaaggt ggtcgatatc
    24721 atctacacgg ccaagtcctt cagccaagtt gaggaagtag ctcatctcag caaggatatc
    24781 tgcaggagtc accgtacgaa ccttgtcatc tgggttagca ttaccaatga tcgttacgac
    24841 gcgatctgga tcagttggag caacaacctt gaatttttga agaacaacag gctcagtcac
    24901 aacggctgca tcgtttggga tgtagacaat cttgttcaag tcgccatcca aatggctttc
    24961 aatgctttca atcacgctac gagtcataat cgtaccagct tctaccaaga tttctccagt
    25021 ttcagggtct accaatggct ctgcaatggt ttggttgagc aaacgtgttt taacattgag
    25081 ttttttattg attttgtaac gaccaactgc tgccaagtca tagcgacgtg ggtcaaagaa
    25141 gcgagccaca agcaagctac gtgagctttc agccgtctta ggctcacctg gacgaaggcg
    25201 ttcgtaaatt tctttcaagg cttcgtctgt acgagagtcc attggattct tgtggatatc
    25261 tttttcaaca gtgttgcgaa ccaattcgct gtcaccaaaa atatcaaaga tttcatcatc
    25321 acctgagaaa ccaagagcac gaaccaaggt tgtaaatgga atcttacgag tacggtcgat
    25381 acgagtgtag gtgatatctt ttgagtcgct ttcaagttcc aaccaagctc cacggttagg
    25441 gataacagtt gaaccatagc ccaccttacc atttttgtct actttgtcgt taaagtaaac
    25501 acctggtgag cggaccaact gagaaacgat aatacgttca ccaccattga tgatgaaagt
    25561 acccatttct gtcatgattg ggaaatcacc aaagaaaact tcttgggtct tgatttcgcc
    25621 tgtttcttta ttgatcaagc ggaaggttac aaaaattggt gctgagtagc tagcatcgtg
    25681 aatacgagct tcttctagcg tgtattttgg ttccttgatt tcatatccaa caaattccaa
    25741 ctccattgtg tctgtgaagt ttgaaattgg caatacatct tcaaacactt ccttaagacc
    25801 gtggtctagg aaagctttga atgagtcagt ttgaatttca atcaaatttg gtaagtcaag
    25861 aacttctttg attcttgaaa aactacgacg ggtacgatgt ttcccgtatt gaacgtcatg
    25921 tcctgccaag atgattctcc tttgtaaata agttccaagc cttgtcaatc aggcttttct
    25981 aatcgccata tggttgtaaa ccccttatca ccgtgtcctc ttgacgaatt ttcagaatct
    26041 ttaagcctct gttacaaatg ctcaaaatct tgaaaaaaag cacaaaaaga gcagctaaat
    26101 ctgacttttt cagaagattt aactgctgtg agccttgtct ggacaatatt tcagacaaaa
    26161 cctacgacaa atgattaccc atattatacc ctatttagct agatttttca aggggattca
    26221 gtaggttttt ggtaattttt ttcccataga aaacttggca tcacattcga atcacgctat
    26281 ggtacaaaaa actgaaaaaa ctattgactg aaaatcattt tcaaggtata ataataaacg
    26341 ttaaggcggt atagccaagt ggtaaggcac ggctctgcaa aagcttgatc gtcggttcaa
    26401 atccgtctac cgccttctat aacttgattt atcaggtttc aaatgaacag aaagcccaat
    26461 ttgaagggct ttttttattt tccctcgaat aaatacgtat aactttaaaa acttttggag
    26521 cgagtttgtg gcagagttct ttccatggca taattccctt ttgaaatcaa ttgaaaaaag
    26581 cttcgtcacg cctggtgaca aaagcctcta gtttattctg tttcttcttc tatttcgact
    26641 tctgtgattt ggacttttac cttggtaaca cgtccattct tcactttatc attggttaag
    26701 ataaactgtt tgttttggct gaccaattca tagctgagtt tctcagtcgt tggaatggtt
    26761 cccactcctg tcaaataata accagcgatg gtatcaacgt catcactttc cagttcaaca
    26821 tcaaagtaat tattgaaatc attgagggtc atagttcctt gaacaatgta ggtatcctcg
    26881 ccaatctgat gaacatctat tgctgctttg tccgtttcat catcaatttc accaacaatt
    26941 tcctctaaga ggtcttccaa agtcaccaaa ccagccatac caccgtattc atccagcaag
    27001 attgccattt gtctttgggt atttcgcagt tcttttagca agtcatccac aaaaatagtt
    27061 tcaggtacaa aaagtggatc ttgtaaaatt ctcttccaaa caatattgtc aaaaccgtcc
    27121 acaaagcctg ccttaaggag actcttggtg tgaatgattc caattacatt gtccttatcc
    27181 ccatcataaa ccgggatacg agaataattt tgttttaaaa tactttggat aatggcttga
    27241 ctatcatcct gaatatccac cataaaggca tccgttcgag gcaccataac ctctcgtgcc
    27301 atcagttcat cgagcgaaaa gacaccttgt agcatctcaa tctcatcagc atccaatgtt
    27361 tcttcactat ttgtcagcat ataggcaatt tcatcacggg tcatcttttc atccgcatca
    27421 tcgaatgaca taggagtcaa atggctcaag aaattggtcg aagcagctaa aagccaaaca
    27481 aaaggactga ctagttttcc gatcccaatg ataatcggcg ctgtacgaat tgccaaggca
    27541 tcctttagat taagagcgat tctcttagga tataattccc caaaaacgat ggaaatatag
    27601 gtcaaaaatg ccaaggatag aaaagttgcc acggcttgtg ctgtttcgcc attcccaagc
    27661 caagaggcaa tcacacgtcc tagagtatca gttaaactcg cccctgataa gattgtaatc
    27721 agggtgattc ctacctgaat ggttgataaa aagtggttag gattttctag taccttcagc
    27781 aggcggatgt agcgtctgtc tccttcttcc gccttttgtt caactcgggc acgattaaga
    27841 gaaaccatgg ccatttctgt ggctgagaaa aaggcattta ataccgtcaa gataaacaat
    27901 aaaacaaatt gtagcaacaa attctgacta cttgggtctt ccatagttct tctcctaaaa
    27961 tagtatctta tcctttatta tatcacaaaa tttaatccaa tacatattat ttttttctta
    28021 gcgtaacttc catctctctc ccaaaactgg aagttagtct aagacggatt tccactgatt
    28081 tcacgcgttt ttctcatact aaaagctagg ttgtgggaaa ctggaagtta gttttagaag
    28141 ttactatttt ttcttagtac ctattctagc cctgcttaaa ctagtaaaaa gaactcctac
    28201 atccataagt gacataggag tttaggctta tcttttactg agttacagtt acttctccag
    28261 ttcggtaatc cagttgaagt cccttttgaa cattgggaac tagaacattg aattccaatt
    28321 ctccatccga agacttggct tcaatctgtg aagctgaggg aactaaatcc tcgtttgaag
    28381 cgtagtaaag ggttacacgg taacggacac gcttgttttg gtccaaggct ttacgcacct
    28441 tgctttcata gtagttttga ccagtcgaat actcggcttg tgcctgattt gcccaggctg
    28501 tctgaacagc aatgttttta ggattgcttg ttgaggcatc aaaaccatcc aaaccaccga
    28561 ttaaggcata gcctaacaaa tgacctctat cgactgcatg ggtataagag ccctttagat
    28621 tcttgacctg atgccaacct ggaggagtcc aagaagttga accattccca gtttctttac
    28681 gattcttgta ctgacgagtg gccttagaca agagggcatt agctacggtt ggaacagttt
    28741 ccttgcccac tgtctttgtt ttattgtcag cgtagggctt acttgaaacc ttggcatcta
    28801 gatttgtttt attaccattg acgataaaag cacctgagcc attccactcc agactcccct
    28861 ttatttgact cttgactgcg tctgttaaga cactctctgc caatgcttga ctaggagctt
    28921 cagacgcttg ttttttctga ctaagattgg ttttgggact attaggtgcc gactgcatct
    28981 gcttgatata atagctccct gtagacaaaa gcaataacac tagcagtccg attagtgtct
    29041 gtcttgtttt tttgttcata tttctcctta tctttagaaa aaggctggtt ctccagccta
    29101 atttcctgta aatttatgaa tcaattcctg ccattttgct ggagacagga tagcccatgg
    29161 atcttgaccc ttgcccaaga ttccataacc taccattaga ccgattccta gagccagagt
    29221 acctaaaatc agtactatga tgactaaaag taaacgattg attacgtagc ttgatttctt
    29281 attcatcttc atcgcttgcc tcaatccgct gaatcttagc acctagctgc gccaacttct
    29341 catggaaacc gtagtaacct ctatccaagt gaaccaattt accgaccaca gtttctccct
    29401 gtgctaccaa acctgtcaaa atcaaggctg cactggcacg aaggtcagtt gaaagaactt
    29461 ctgctccctg caaaggctgt ccaccaacaa tacgagctgt atcacggata atctcagaat
    29521 gcaagcccat gcggcgcatc tcttctaggt gttggaaacg attttcgaaa actgtctcca
    29581 ccatggttga ttcgcctttt gcaactgtca tcaaggctgt aaattgagcc tgcatatctg
    29641 ttggaaatcc tgggtggggc aaggttttca catgaacagc ttttagattt tctagttgag
    29701 aacgaacacg aattccttcg tcttcttcaa ttacttcaac acccatttca agtaacttgg
    29761 caatcaaggg acggttgtgc tcccagacag cgtctcgaat caagacatca ccaccagtca
    29821 tggcagcagc taccataaag gttcctgctt cgatacggtc ttggactaca ttgtgagtcg
    29881 taccatgaag tttctcaaca ccagtaatgg ttatagtctc tgtaccagca cctttgacct
    29941 tggctcccat ttcattaagg agaatggcta agtcaacaat ctcaggctca cgcgcagcat
    30001 tctcaatcac tgtcacccca tcagccagag tcgctgccat catcaagttc tgcgttgcac
    30061 caacacttgg aaagtccata tagatatgag cgccatgcaa gcgttctgcc ttggcttcga
    30121 tgtaaccagc tgtctgacta atcttaaccc ccatagcttc cagacctttc aaatgaagat
    30181 caataggacg gctaccaatc gtacaaccac ctggcatgga taccttggca tgacccacac
    30241 gggcaaggat tggccctaat acaacgatgg aggcgcgcat cttgctgaca tacttgtaag
    30301 gggcttcctc agtgatgtcg ccagtagcat ccaccttgac aagatgagct tcctcatcaa
    30361 agtcaacctt ggcattcaaa ccaccaacta cctgattcat aataaagaca tccgacaaaa
    30421 tcggaacatt ctgcaagacg gtctttcctt cacttgctag aatagtcgct gccaacaagg
    30481 gtaagactgc attttttgct ccctcgatcg tcacgcttcc taccagacga ttatcgccac
    30541 cttgaaccac aattttatcc atactcgttt cctttactct tgattttata ataatcctct
    30601 aagcgcttct tgccacaaat gatacaggct aataaagaaa gaactcagga tgtagcctat
    30661 gacaatgcta aaaaaggcta ctaataaacg aacttttctt gtattatcat ctgtcacttt
    30721 taaaaccttc tcccatctaa caagatcctt taaaaggtaa aaactcacat aaataaagag
    30781 catatgacta cttagagtga ataataattg aaccatttga ctattatacc atcttctctg
    30841 tttgtgcgct agtttggaaa cttcactcaa aaattaggga ttgtttttca agtaatcaat
    30901 cgcatcttgt agggttttaa cgggcacgat tttcatatcc gtcttgattg ttttagccgc
    30961 ttctagggct gtttggtagt tgtttttcgc gtccagatgc gccttttgtt cttcttcgct
    31021 aacagggtta tcaggagcaa agaaaatagc agcacctgcc ctagccgaag ctacaacctt
    31081 cttatcaata cctccaatgt ctcccacatt accatcgcgg tcaatggtac ctgtaccggc
    31141 aacaatacga ccattacgaa gatctgggtg agctatttga gtatagatag ctagactaaa
    31201 catgagacca gcacttgggc cgccaatacc agctgttgaa aagctaattg ggacattgct
    31261 gattacctct gtacggtcaa tcaagccgat tccaattcca tttttgccat tttccaaggt
    31321 gataatcttt ccttctgcag acttggtttg cccatcctct tcataggtga ccttgacgga
    31381 atcccctaat ttttgagaac tgacgtaatc aatcaagtct ttggaactat caaaggtctg
    31441 atcattgact gctgtgactg tatcagagat attgagaatc cctttaaagg ttgaattatc
    31501 cgtcacattc aaaacataaa ctccaaagta cttgagttcg atatccttac cagctgtttt
    31561 tagtccttga tacttggcca tattttgcga tgtttgcatg tagaattgat tgattcgcat
    31621 aaattcaaca tcggaagaac cacctgtagt ctcctgagca ctacgaatat ctgtaaaagg
    31681 tgtcaaccaa gcataaatca tatgagctaa agtggcatgt tgaacaccaa ccgtaacgaa
    31741 ttgataggca ccagcttcct tatcttctgt gtcatttact ttaaggactt ggcgaatatc
    31801 ttccgaacca cctggaacct ctatataata aggcaagggc actacaaatg ccaagaaagt
    31861 cacaatcaag gccgcaatga cgtataaggg ccatctaatc ttttttttca tttcttattt
    31921 cctccaaaat actctcggga acatggcagg caatatcctg accaaacttc aaaagctctc
    31981 gaacacctga tgaactgata tagagatgtt caggccggct atgtaaataa atagtctcta
    32041 tatcagaaga cagctgatga ttgtagtaat caaaactagc ttcatattgc aaatccgccg
    32101 cattcctcaa cccccgtact aggaaagtag cccccagtct ttttgcaaca tcgaccacca
    32161 attcatcatg agaagccacg acttcaacat tttccaaatg tcccaaagcc ttttctagcc
    32221 cccgtttacg attttcaaga gggagaaatc cttgtttgtg gggattaaaa aaaataccca
    32281 cataaagctt atcaaaaagt ctgctcgccc gttcaatgat atccagatgc ccatttgtca
    32341 tcggatcaaa tgagcctgtg aataagccaa tcttatctga catagactgt caccttacta
    32401 attccataaa tcttttcctt ccagataccc agacaggcaa tctcttctgg aagttcaacg
    32461 gccttatccg tctcgcacac aaccataaca tcttcagaaa aaagctctct cttagccatt
    32521 ttttcaatat ctgctacgat ttgttccttg gcatagggag ggtctaagaa aacgaggtca
    32581 aattccccag atacctgttc caatgccctc tctgcatcca tcttgaggag ttgaaatttt
    32641 ccaacttcct tggtcatctg gatattttca gccacgatgg tctgagcctt acggtctcgc
    32701 tccaccaaaa cagcactgga catgccacgc gatactgctt cgatagataa accaccacta
    32761 cctgcataaa ggtccaagac tcgtccccct tcaaagtagg gaccaatcat gttaaaaatg
    32821 gctcccctaa ccttatccga agtaggtctt gttgtcttgc cttctagtgt cttgagggga
    32881 cgtcccccat agattcctga tacgattttc atactgttta ttataccaaa ttatagacaa
    32941 aaagagaaag aaaaccgaac cttgcggttc gattctctac aaaatatttt cgtaagtatc
    33001 gcggacttct tgaggccaaa cacttgtttg cacttctccg atgtgtctct tgcgaagtag
    33061 gaacatggcc atacgagatt gtccaattcc tccaccgatt gtcaatggga ataggccatt
    33121 caacaaagac ttgtgccatt ccaattccaa gcggtcttca tcacctgtaa tttccacctg
    33181 acgtctaaga gtttcttcat ctacacgaat tcccatagaa gacaactcaa aggctccacc
    33241 taaagactca ttccagacaa gaatatcacc atttagaccc ttgtagccat tctcagactc
    33301 gcttgtccag tcatcatagt ctggtgcacg tccatcgtgc ggtttaccat ctggcaactc
    33361 gccaccgata ccaatcaaaa agacggctcc aaattcttta caaatcgcat tttcacgttc
    33421 tttcggtgtc aagtctgggt agcgttctac caattcttct gtatggataa aggtgatttg
    33481 ctttggcaag atagactcga tgtcatagcg agcttcaaca gctagctcag tcaggcgaat
    33541 agccttataa atcttctcaa ctgtttcttt tagataaacg atgttacgct taccatttgg
    33601 gataaccttc tcccagtccc actggtcaac ataaacagag tgggttgcat ccaaggaatc
    33661 ctcatctgga cgaagggctt tcatgtggac aaagagaccc tctccttcac caaagccaaa
    33721 acgagccaag gtgtggcgtt tccatttagc aagtgagtgc accacttcat aagtagcatc
    33781 agggatttgg agaaccttga ccgatactgg attttccaca ccagacaggt tgtcctgcat
    33841 tccgtcaccg accttactca agataggacc ttgaacttcg acaacttcta gcttatcttt
    33901 caaatactgg gtaaaagtgt ttttgacaaa ggaaatttct tcttgttgat ggataaaact
    33961 tttcttcata gacaactcct caaaaattta ataaacgtat tatacaccta tttccaagaa
    34021 aagaaaagag aaaatttaaa aaaatcagtg tcactcaaaa cactgatttc atagaccttt
    34081 tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa atcaagatag
    34141 atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga ttgttcatag
    34201 gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa aaccatggct
    34261 acgctaatca tataatcaaa gaagccacta gccaagaaaa tattgactac catagcaatc
    34321 agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc tttcttggta
    34381 aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa ggcagataaa
    34441 actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt taaaacggag
    34501 taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct actggcaacg
    34561 aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc ctgcatcaac
    34621 aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa agcagatagt
    34681 ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag acctgcacgg
    34741 tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt tccttgatta
    34801 taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg caactgcaac
    34861 attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg cactttcagc
    34921 cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat tttctataga
    34981 aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca ctgggatagc
    35041 taccttttta gtttcgtcaa gaagcgctgg actagtcatc cggtaaatgg gcagatggaa
    35101 atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg acttatctga
    35161 aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc ctacattacc
    35221 gggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag cttgtcctac
    35281 ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg ccaaatctag
    35341 caaaatatcc tctgacaccc agacagtttg cgaaaaagta gctaactgat ctcgataatt
    35401 ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt caaacaagtg
    35461 ccagccttca atcaaatagg cagacttgcg gtattttttt tggcgtaatt tcttggcatt
    35521 ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat aacacaatca
    35581 aagggggttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca gggagtcggc
    35641 tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg tcgagtatgg
    35701 aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc tatcatggca
    35761 aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag ctacttagat
    35821 gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta ggtctccaga
    35881 actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt aaagaaggaa
    35941 taaaaacagt gaaatctatt aaacgttttg cattctcggc tatgggagtg gctatgttgc
    36001 ttgtcttgac tggctgtgtc aatgtcgata aaaccacagg tcagccaaca ggatttattt
    36061 ggaatacgat cggagcgcct atggctgaag ccatcaagta cttcgctact gataaaggtc
    36121 taggctttgg tgtcgctatc attatcgtaa ccattatcgt acgcttgatt atcttaccac
    36181 ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac gctctcaagc
    36241 atgtccttga gccacaccaa acacgtctca aagaagcaac tactcaagaa gaaaaactcg
    36301 aagcccaaca agccctcttt gccgctcaaa aagagcacgg catcagcatg tttggtggtg
    36361 taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac tttgctgccc
    36421 aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt tctccaagta
    36481 tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt tcacttcacg
    36541 gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg agcccactca
    36601 tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg gttgtcggtg
    36661 gtttcatgat gattctccaa cagtttatcg tcaactatat cgttcgtcca aaacttcgca
    36721 aaaaagtccg tgaagaacta gccaagaacc caccaaaagc aagtgctttc tctaaaccaa
    36781 gtggacgaaa agacgttacc cctgaacaac caactgctat cacaagcaag aaaaaacaca
    36841 aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta gctgatttgc
    36901 taagtctttt tgcaaatcaa aagcccgatg tttccatcag gcttcttttc tatccatgta
    36961 cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg ttcttgacgc
    37021 gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt tcacgccact
    37081 tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt ttgagggtct
    37141 tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct ggaactagca
    37201 cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa gccaagatat
    37261 ttttattagt ttggctagtg acaatcttgt gctgttcttc gttgatttcc ttgatatcca
    37321 aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa cgtggtttat
    37381 tacggaaagg aagagcacag gtatccaagg tacagtggat tccttgttcc ttagccttgg
    37441 tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg actgtaatcc
    37501 cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca tcatctaccg
    37561 tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg caatactggc
    37621 aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca tctactgacc
    37681 caaagctttc tgtcgaatgc accattcctg tcacttgtcc ataatcaatt gtttcttcag
    37741 acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga cttgaaggaa
    37801 aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca ttttcaatct
    37861 attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt cctcagggcg
    37921 ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt ccgcagaacg
    37981 taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat catgaattac
    38041 cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt tatcattgtt
    38101 ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat gggtcacgtt
    38161 gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg ctgaggcatc
    38221 cacacctaga taggtacggt aggtttcctt cttatgagtc actcttgtga ctagagcacc
    38281 gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac caagacctgc
    38341 tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg cgatatcgtt
    38401 cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga taaagtctag
    38461 cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac gagccaactc
    38521 tggataatag agatgggtca cggtattgga cgctaggaag gagtgaatcc caaaagtctt
    38581 ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg tcatgccaaa
    38641 cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc ctccaggatt
    38701 ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt caatatcttc
    38761 aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt ccttgtctgg
    38821 cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat ggctcatcaa
    38881 aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa ttttcaaaat
    38941 agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt tccacgaaaa
    39001 agcttggttg acggctcttg ccttctcacg aatccccttc tcatcataca agtgaaaggg
    39061 agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg gtgttttcat
    39121 aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa cctttagttc
    39181 tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg cttggttctt
    39241 gacatcaata ttggttacct tcaagagtga cttgtagtca aactgctttt cacgttcttc
    39301 ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact cgcgcaagag
    39361 actaatcata ccattgaccg ttccgccacc tttcaagaag tcatccacaa tcaagacacg
    39421 gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt caccacttga
    39481 acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt cacggcgcac
    39541 aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca cacccttagt
    39601 tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa taatacgacc
    39661 aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat aaccacctgg
    39721 caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt ccttagcatc
    39781 ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca ctgtctggat
    39841 atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt ctgagatgga
    39901 tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt tataaggatt
    39961 attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt tcatttctat
    40021 ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg tcgctggtgg
    40081 ttcaaaacac tgttttgaga ttgtcaatag aactgacaaa ccctgtaata tacctgcata
    40141 tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga gtattcattt
    40201 ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta tcctaaaaaa
    40261 tgctcatttt tcttaaatta tcaatctaaa tctggtttat agaaggaacg attatccata
    40321 gcgaagattt tattggtcat ctctccttta tccaccaaag ccagagctgt tgacatcatc
    40381 atcatgcttg catccagatt gtcaatcata tggataatct ctgcctccat aatacgtgga
    40441 cggactggac ttccatattc aagcaagccg tggtgactga ggatgacatg acgaagcaaa
    40501 acgacttctt ccttggtatc atcgatgccg agttccataa ctgtcttggt aatttcgcta
    40561 tcaatgagag cgatatgtcc aagaagatta cctcgcactg tgtactctgt ctggtctggc
    40621 cccgtcaact cgataacctt agctaagtca tgcagcataa tccccgcata gagcaggctc
    40681 ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgtaccat ggtcgccgta
    40741 tgataagcca accccgtttc aaaggcatgg tggttggtct tggcagctgg ataggagtag
    40801 aattccttat catacttggt gtagagattt cggacaatcc gttgccagac aggattttca
    40861 attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac tggtgacttg
    40921 accttgaaat cggctgggtc attgggttca ccagcttgag gcaggcggag agtaatttga
    40981 ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac aaccttacct
    41041 gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc aatctcgcca
    41101 ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg cctcaggtca
    41161 gctgatttga ttaggtaaaa gccttcaaat agctcatctt ttttcatgtg actaatcttc
    41221 atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac cttctgacaa
    41281 ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata attcatcaat
    41341 attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac caaacttgcc
    41401 aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct tttggatatt
    41461 aagggtcttg aaaccaactg atagagagtt aagaagggct gatagggtac ttggtcctgc
    41521 aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc gcacaatctc
    41581 tgaataaaga ccttctgtcg gaacaaacaa gattccaaag ttggttgtcc gaggtggtgc
    41641 tatgtacttg ttcctaatat ccctagcaaa gcgcttgacg cttgctagga gtgacttacg
    41701 acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc ggtaataatc
    41761 tgccagtgga aacttagagt caattggcag atagacgtat tcttggtcgc cttgtccggg
    41821 taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt attctcgttc
    41881 gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt ctcccagaat
    41941 ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac gggcaactgt
    42001 ctgcatttct ccaaggccac gattgacaga ctccagttgt ttagaaactg tctcaaagga
    42061 agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct ggcgcatttg
    42121 ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg tcttgtctct
    42181 agtttggagg agattatctg tcatttcttg acggacttgg gtcagacctt ggtgcaattc
    42241 aatccgcact tcttgcaaac ggtcgctgac aaccacttcc aaatcttttt ggtctaactg
    42301 gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat gatctgcctg
    42361 atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc aaatcagaaa
    42421 gagaccagct agattggcaa ttaataatag aataagtaaa ctttccatcc tacctcctgt
    42481 ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact tccctatcta
    42541 tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc aactcatact
    42601 tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga tagtcgtagt
    42661 ctgaacgagg ttctagctga ctgattcctt ctggacaata agtaatcaag ttttgcccat
    42721 cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc agaaagacat
    42781 tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc tgagcctgag
    42841 gattttgctt aaagatggtc aagagagcca attccaaatc agtatcatct ttttctggcc
    42901 gggcttggac aaaatactgg gcacgttttt gaatcacctg tcgctcttct tccgtcacag
    42961 aatcaaaatc tccgactgct agagcaagag gcaaatcttc ttccaagatc cagagcgagc
    43021 ctcgatccac accaacaaaa ccatcaaagt ccgtccgata atgaccgcgg tctccgcctg
    43081 caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc attgacatct
    43141 cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt ggattgagca
    43201 atagtttggt catcaatccc accatccact tcaatctcaa agttcaaacc tttttcatca
    43261 cgaagggcaa ccagctcacg aaccttatcc atggtttctg gcagaaaggc ttgaccacca
    43321 aatccagggt taactgtcat gactaggact tggtcaacta gatgaagcac atgcttaatc
    43381 gcttcaactg gtgtaccagg attgataaca actgatggct tgacaccgag tgaacgaatc
    43441 ttttggaggg caccatgaat atgaggcgtt gcttccacat ggatactaat aatatccgca
    43501 cctgcacgca caaagtcctc taaatgatgc tcagggtttg acaccatcaa gtggcagtcg
    43561 aaaaccatct tactatgagg acgaagagct tcgaccacac ccgcaccaaa actgatttgc
    43621 ggcacaaaat gaccatccat aatatcgata tgggcatact ctgccccagt tgcttctagg
    43681 cgtttaattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg agcaatcttg
    43741 tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt tataggtttc
    43801 tctgcgattt tcaatttcgc tgaggaattg caggtagttg tcaaaacgga agggtgcaat
    43861 ggtaccttct tcaactgctg gcttgacagc acaggacggc tcatgggtat gggtacaagt
    43921 acggaatttg cagtctcgac tgacagtggc aatctctgga aaggcctgat tgaggtcttc
    43981 agccgttgat acttcataat ccagtgatga aaagcctggt gtgtctgcga ttttaccccc
    44041 attgaggttg taaaaactaa cagctcgagt ggtatgacgc ccgcgaccca gactgtctga
    44101 aatttctccc gtttcaagat taagatctgg tgcgatttta ttgagaagag ttgatttccc
    44161 aacacccgtc tgccccataa agaccgtaac cttgcctgtt aacaaaggca ggagttcctc
    44221 tttactggtc acaaagtcat atccgatgtc accataggtc tgctggtaaa aatccagttc
    44281 tcccccgtct tccaacaaat ccattttaga aatatagacg atgggatgaa tacccttatg
    44341 ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt ccttgacaga
    44401 catgattact acagcttggt cgatattgac aataggcgga cggaccagac tgtttttccg
    44461 ttcgtgaatc ttgagaatat agccttctga attttcctcg gcagagaaat ctacccagtc
    44521 cccaacgtaa ggggtatgcc cttttttacg gaaattccca cgcgcgcgtg tttgatagac
    44581 ttggccatca ctctctacat agtagaaccc agccaaggct ttaatgattt gtccctgcaa
    44641 aataactcct ttaaaattgt tagttccatt ataacaaaaa aaagctattt tagcttagct
    44701 tctctttaca atttcgataa gtctattcta aaagaaaaag atacactcac gctttagata
    44761 ccaagtttta tacaaaaata acgaatctac ctccttatat aaaaacaggc gaacagagag
    44821 cctaaaactc cctgttcgct ttactttttc tgtgtgtaat agaaaaaacc taataaagca
    44881 agacaaaaaa tatgaatata aactccatac atcatgtggg gaaagacaga ctctataaaa
    44941 tagcctggta gatagatgat tggaaattga tagaaatcat aggtcgttag agatagtaaa
    45001 caaagaacat acataaatac tgctacaatt agaacccatc cttgctttcg ccatagaaaa
    45061 atcatcaata agaacagaca aagtagatag attgaccaat ttcgcaacat aaattgaaaa
    45121 ccataaatca tactttcagt cgtttctcca tcaatcacat caactacttt atagaaaggt
    45181 aaacaatagc tcactaaaaa aagaagggga ctaattattt ttttcatatt ctctaccatg
    45241 gattattttg caagtaagct gaccatctat ctccatatcg aatcaaatta acagtataat
    45301 tagttactac ccgattttca cctggtccaa ccttagaaaa acctgtgcta tactcccaac
    45361 tacttcttgc acctggatga aaccattttt gctgggatga ataccaacca ccttgtctaa
    45421 cttccacact tgaagattct atttcgatat ccctttcatg gaagtcaact cctccactta
    45481 ttttagtaat atttttttgt acacctccat cataactcac ccagtgaaca acagtataca
    45541 attccacact ataagtacta tcaaactgac tttgatgagt agtaatgttt tgagtataag
    45601 cgtgcacttt ctgtatacca aaaatatggt ctaatatatt cgttggttta gcaagcttat
    45661 tgtaaccctc ttcaacaaaa gtagccttct ctaaatcagc ggtataaaca gtttttcctt
    45721 gtactacttg attgtttata gaagtaatac ggctatccac aacaatgggg gccaccatat
    45781 ctccatcgct agtttctatt ttagctgcct ctttcacctc atatacaact cgattttctt
    45841 cagactgaat cacttctacc ccattttttt caggtataga taatctagtt tgcccattag
    45901 aaaccgttat atttggacca atattcttct catttgcata agtcgcaata ggaaatcctg
    45961 atagaaccac tgcacacata aggctattga ctaatttttt tctcatgaat atatccttcc
    46021 cattttcaag aggagtaaaa atagctaata taagatgaac gtttccttat atttcagaat
    46081 aggatatcta tctgaaagca attcacactc ctataggtaa ctgttccaaa tcttggctac
    46141 atatatttca atagtttgct acaaaaaact cctttctaag tctattgaac atgcccttat
    46201 tcacctacta atatatcaca aaaataaata aatacaagac tgttttttct actagtttta
    46261 tgatagaata gtattgttag ggtaaatttc atatataaat gtcgagtgaa aaatcgatgg
    46321 agcagaaatc ggtagacaaa gactcgattt cgttggtcca gccccacaag gctaatcagg
    46381 tatttcacga gtttaaaaat ctaatgaagt gcccaatcaa ctactgattc attgatttaa
    46441 tacgaactat agtggattga acctagaaat agtacactaa ggattctaaa acgtttctag
    46501 aaattaattt gactttccta atctctttgt tcatatctta tttcaatcta ctatatatac
    46561 caaaatgctg ggacaaaagt ctttaaaatc agagaaacgc atattatcag gtgttggaaa
    46621 accttgataa tatgcgtttt atcatagaaa gatctacttc attttttacc aaaattaagt
    46681 ttttgtccct gcatcttaga gtccttgccc tttaagtgca tctgctaggc tggcaaactc
    46741 ttccaagctg agagcttccc cacgcacact tggtgacaag cctgcttggt ccaaagcctt
    46801 ggtcagcttg tccttgacct cttcagtctt gccaaagtaa cctgtcaagt tattccacaa
    46861 ggtcttgcgg cgatgggtaa aactagcctt ggaaacctta aagaaaaagt tctcgtcttc
    46921 cactgctaca gctggcactg gacggcgcac cattttcaag atggctgagt ctacatttgg
    46981 tgctggcaca aagactgtac gcggcacgat aaaggcaacc ttggctgtca tgtaatactg
    47041 cacagcgata gacaagctac cgtaagcctt ggtatttggt tgagccgaga tacggtccgc
    47101 cacttctttt tgcatcatga ccacaaactc actaaaagga atgccactct cgattaagtg
    47161 catgagaata ggcgttgtga tgtagtaagg caaattagcc actaccttga ttggcaggtc
    47221 aggatttttg aaattctgga tatgttgcgc caaatcgacc ttgagaatgt cctcgttgac
    47281 tacagtcaca ttgtcaaaat cacgcaaggt atctgccaaa atcggtacca aacgatggtc
    47341 gatctcaaag gccataactt ctgctgcacg ctcagccaaa aactcggtca aggcaccaat
    47401 acctggcccg atttcaatga cattgacctg gtcatcaatc tcagccgtat ccacgatttt
    47461 ttgtaggata ttggtatccg tcaagaaatt ttgcccaaag gactttttaa aggtaaaacc
    47521 gtgacgctcc agcactgcct tggtcacgct ataatctgca attctcatct attctctttt
    47581 ctattatctg ttactactat tgtaacacat tccccttgta ttttgggggt gaaaatcata
    47641 ccaaaaaact atctttcctc atgaagaaag atagtcttgg aaatctttaa aagtggcctt
    47701 agcgcttctc tcgaaacata cgtt
//
LOCUS       DAVBNN010000011        45515 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBNN010000011 DAVBNN010000000
VERSION     DAVBNN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.011"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..112)
                     /locus_tag="VQ847_000643"
     CDS             complement(<1..112)
                     /locus_tag="VQ847_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050026.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSF"
     gene            complement(109..915)
                     /locus_tag="VQ847_000644"
     CDS             complement(109..915)
                     /locus_tag="VQ847_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050027.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITFGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(896..2053)
                     /locus_tag="VQ847_000645"
     CDS             complement(896..2053)
                     /locus_tag="VQ847_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050028.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(2213..3118)
                     /gene="murB"
                     /locus_tag="VQ847_000646"
     CDS             complement(2213..3118)
                     /gene="murB"
                     /locus_tag="VQ847_000646"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3050029.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(3230..3982)
                     /locus_tag="VQ847_000647"
     CDS             complement(3230..3982)
                     /locus_tag="VQ847_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET3050030.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFTKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(3992..4723)
                     /gene="budA"
                     /locus_tag="VQ847_000648"
     CDS             complement(3992..4723)
                     /gene="budA"
                     /locus_tag="VQ847_000648"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3050031.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            4865..6136
                     /locus_tag="VQ847_000649"
     CDS             4865..6136
                     /locus_tag="VQ847_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3050032.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(6156..6982)
                     /locus_tag="VQ847_000650"
                     /pseudo
     CDS             complement(6156..6982)
                     /locus_tag="VQ847_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(7139..7792)
                     /gene="phoU"
                     /locus_tag="VQ847_000651"
     CDS             complement(7139..7792)
                     /gene="phoU"
                     /locus_tag="VQ847_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3050033.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(7804..8562)
                     /gene="pstB"
                     /locus_tag="VQ847_000652"
     CDS             complement(7804..8562)
                     /gene="pstB"
                     /locus_tag="VQ847_000652"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3050034.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(8575..9378)
                     /gene="pstB"
                     /locus_tag="VQ847_000653"
     CDS             complement(8575..9378)
                     /gene="pstB"
                     /locus_tag="VQ847_000653"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3050035.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(9389..10273)
                     /gene="pstA"
                     /locus_tag="VQ847_000654"
     CDS             complement(9389..10273)
                     /gene="pstA"
                     /locus_tag="VQ847_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3050036.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(10263..11180)
                     /gene="pstC"
                     /locus_tag="VQ847_000655"
     CDS             complement(10263..11180)
                     /gene="pstC"
                     /locus_tag="VQ847_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3050037.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(11180..12058)
                     /gene="pstS"
                     /locus_tag="VQ847_000656"
     CDS             complement(11180..12058)
                     /gene="pstS"
                     /locus_tag="VQ847_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3050038.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(12632..13936)
                     /locus_tag="VQ847_000657"
     CDS             complement(12632..13936)
                     /locus_tag="VQ847_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3050039.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(13937..14710)
                     /locus_tag="VQ847_000658"
     CDS             complement(13937..14710)
                     /locus_tag="VQ847_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3050040.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(14700..14978)
                     /locus_tag="VQ847_000659"
     CDS             complement(14700..14978)
                     /locus_tag="VQ847_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3050041.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(14978..15379)
                     /locus_tag="VQ847_000660"
     CDS             complement(14978..15379)
                     /locus_tag="VQ847_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3050042.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(15589..16206)
                     /locus_tag="VQ847_000661"
     CDS             complement(15589..16206)
                     /locus_tag="VQ847_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3050043.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLPIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(16196..16969)
                     /locus_tag="VQ847_000662"
     CDS             complement(16196..16969)
                     /locus_tag="VQ847_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3050044.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(16980..17717)
                     /locus_tag="VQ847_000663"
     CDS             complement(16980..17717)
                     /locus_tag="VQ847_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3050045.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWKEIKKA"
     gene            complement(17722..18852)
                     /locus_tag="VQ847_000664"
     CDS             complement(17722..18852)
                     /locus_tag="VQ847_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3050046.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLNLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(18936..19325)
                     /locus_tag="VQ847_000665"
     CDS             complement(18936..19325)
                     /locus_tag="VQ847_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3050047.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(19341..19724)
                     /locus_tag="VQ847_000666"
     CDS             complement(19341..19724)
                     /locus_tag="VQ847_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3050048.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(19725..20513)
                     /locus_tag="VQ847_000667"
     CDS             complement(19725..20513)
                     /locus_tag="VQ847_000667"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3050049.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(20506..21441)
                     /locus_tag="VQ847_000668"
     CDS             complement(20506..21441)
                     /locus_tag="VQ847_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3050050.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(21571..21747)
                     /locus_tag="VQ847_000669"
     CDS             complement(21571..21747)
                     /locus_tag="VQ847_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3050051.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(21887..22594)
                     /locus_tag="VQ847_000670"
     CDS             complement(21887..22594)
                     /locus_tag="VQ847_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3050052.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            22745..23773
                     /gene="queA"
                     /locus_tag="VQ847_000671"
     CDS             22745..23773
                     /gene="queA"
                     /locus_tag="VQ847_000671"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3050053.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(24434..24823)
                     /locus_tag="VQ847_000672"
     CDS             complement(24434..24823)
                     /locus_tag="VQ847_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3050054.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(24877..25568)
                     /locus_tag="VQ847_000673"
                     /pseudo
     CDS             complement(24877..25568)
                     /locus_tag="VQ847_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(26283..26834)
                     /locus_tag="VQ847_000674"
     CDS             complement(26283..26834)
                     /locus_tag="VQ847_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050055.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(27184..28008)
                     /gene="nadE"
                     /locus_tag="VQ847_000675"
     CDS             complement(27184..28008)
                     /gene="nadE"
                     /locus_tag="VQ847_000675"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3050056.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(28005..29465)
                     /locus_tag="VQ847_000676"
     CDS             complement(28005..29465)
                     /locus_tag="VQ847_000676"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3050057.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(29581..30069)
                     /locus_tag="VQ847_000677"
     CDS             complement(29581..30069)
                     /locus_tag="VQ847_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050058.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(30059..30268)
                     /locus_tag="VQ847_000678"
     CDS             complement(30059..30268)
                     /locus_tag="VQ847_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3050059.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(30654..31134)
                     /locus_tag="VQ847_000679"
                     /pseudo
     CDS             complement(30654..31134)
                     /locus_tag="VQ847_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(31150..31272)
                     /locus_tag="VQ847_000680"
     CDS             complement(31150..31272)
                     /locus_tag="VQ847_000680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050060.1"
                     /translation="MSGNIQNSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(31294..32028)
                     /locus_tag="VQ847_000681"
     CDS             complement(31294..32028)
                     /locus_tag="VQ847_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050061.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(32363..32833)
                     /locus_tag="VQ847_000682"
     CDS             complement(32363..32833)
                     /locus_tag="VQ847_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3050062.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQ
                     LFGARRKIPEYKFVAEVISYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HDAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            complement(32854..33093)
                     /locus_tag="VQ847_000683"
     CDS             complement(32854..33093)
                     /locus_tag="VQ847_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3050063.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHIPDMIENGVDNLKIEGRMEWSLFTTYQQ"
     gene            complement(33342..33653)
                     /locus_tag="VQ847_000684"
     CDS             complement(33342..33653)
                     /locus_tag="VQ847_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050064.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(33668..34954)
                     /locus_tag="VQ847_000685"
     CDS             complement(33668..34954)
                     /locus_tag="VQ847_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3050065.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            35577..35759
                     /locus_tag="VQ847_000686"
     CDS             35577..35759
                     /locus_tag="VQ847_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3050066.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            35769..36119
                     /locus_tag="VQ847_000687"
     CDS             35769..36119
                     /locus_tag="VQ847_000687"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3050067.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            36127..37317
                     /locus_tag="VQ847_000688"
     CDS             36127..37317
                     /locus_tag="VQ847_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3050068.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(37832..38824)
                     /locus_tag="VQ847_000689"
     CDS             complement(37832..38824)
                     /locus_tag="VQ847_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3050069.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            38984..40738
                     /locus_tag="VQ847_000690"
     CDS             38984..40738
                     /locus_tag="VQ847_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050070.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            40722..42443
                     /locus_tag="VQ847_000691"
     CDS             40722..42443
                     /locus_tag="VQ847_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050071.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            42454..43038
                     /locus_tag="VQ847_000692"
     CDS             42454..43038
                     /locus_tag="VQ847_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3050072.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            43038..43733
                     /locus_tag="VQ847_000693"
     CDS             43038..43733
                     /locus_tag="VQ847_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3050073.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            43721..45085
                     /locus_tag="VQ847_000694"
     CDS             43721..45085
                     /locus_tag="VQ847_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050074.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        14361 a         9347 c         8098 g        13709 t
ORIGIN      
        1 taaagctatt catatcatca ccagcattaa aggcatagcc aatcaagtaa aaaatcggca
       61 ggtagaggac cagaaagacc agtcccagat aaaggttggc aaattttttc atcgttctct
      121 cctttccttg gtcacccaca tggtgatgaa catggtcagg atgagaatca caccgatggt
      181 tgaacccata ccatagttgt cattggttag aaaattctgc tcaatagccg tcccaaaggt
      241 gataacgcgg ttcccaccaa tcaaacgggt cagcatgaag agactcaaac ttgggataaa
      301 gaccgactga accccacttc gcacaccgtt catagataga gggaagatga catgacggaa
      361 ggtctcccac ttagttgcac caaggtcgta actagcattg atgagattat tatccatatc
      421 gtctaagaca ttgaaaatcg gcaaaatcat aaaggggagc tcgatgtagc ttgcgacaaa
      481 gataaaggaa aaatcggtaa aaagcaactg ttgtgaacca attccgataa attccaagaa
      541 ttggttaata gagccatttt gaccaaaaat cccgataaaa gcataggctt taaggagcaa
      601 attgatccag gtaggaagga taatcagcat gagccagagt tgacggtgct tgagacgggt
      661 caaaaagagg gctgttggat agctgataag caaggtcaca aaggtcacaa tccctgcata
      721 aagcactgag ttgaaactca ttttgaggta ggtcaagttt tgtgacgcaa agtaagattt
      781 ataattttct aaactaaact ggccttcaat gttgaaaaag gattgtccga aaatcaagac
      841 caagggtgcc aatacaaaga gggcaatcca aagcatgtag ggcactacaa agagtttaga
      901 gcttgttttc ttcatctctt tcctcctcga tcgcattgat cagacctgct tcttgctctt
      961 cgatttccac gtattcttcg atacgagcat cgaactcttc ttcggtttca ttgagacgca
     1021 tgatgtggat gtcttctgat tcaaagtcca gaccgatttc ctcacccacg atggccttac
     1081 gggttgagtg gatcatccat tcatttccaa gttcgtcata ggcgataatt tcataatgaa
     1141 ctccacggaa gagctgggtg tcgaccttaa cttggagttt gccttcttca ggaagggtaa
     1201 tgcgcaagtc ctctggacga ataacgacct caacaggttc atttggcttc atcccaccat
     1261 caaccgcttc aaagcgtttg ccgttaaatt cgaccaagta gtcctcaatc atggtacctg
     1321 gcaagatgtt tgactccccg ataaaggtgg caacaaagtg gttgattggc tcatcgtaga
     1381 tgtccacagg ggttccagac tggacaatct cgccatcatt cataacgaaa atccagtcac
     1441 tcatggcaag agcttcttcc tgatcgtgag tgacaaagac aaaggtaatg cccaatcgtt
     1501 gttgtaattc acgcaattcg tactgcatgt ctgttctcaa tttcaagtcc agcgctgata
     1561 aaggctcgtc caacaagacc acacggggtt ggttgatgat agcacgggcg atggccacac
     1621 gctgacgttg tcctccagaa agtttgcgga tggaacgttt ttcataacct tccaactgaa
     1681 ccatcttgag aacttccgct acacgctgct cgatttcttt cttatcaatt ttacgcaagc
     1741 gaagtggaaa ggcaacattt tcaaacacat tcatatgtgg gaacaaggca taggattgga
     1801 agacggtatg tacgtcgcgc ttgttggttg gaatatcatt gatacgaaca ccgtctagca
     1861 tgatatctcc tgtcgtcgca tccagtaaac ctgcaataat gtttaggata gttgatttcc
     1921 ccgaaccaga tgcacctaga agggtgtaga atttcccttc ttccaactca aagttgatgt
     1981 ctttgagaac cttggtgttg ctgtcttcaa aaactttaga gacgtttttg aattcgataa
     2041 ttggtttttt caattggcat aaattccttc tttttcatag attaaccgat cggggctctg
     2101 tcaggtcccc actacctctt gcagggagta aaaccacctg catacatctt cgctaccgat
     2161 aggctttcac cccctttcca tgacatagca gcagcttttc aaatacagct tcctacttgc
     2221 tttcacccaa gatccggact tctctttcaa gcgtaatacc tgagtgttcc ttgacttttt
     2281 cgataaccga ttggatcaag tcctcgtagt ctttggccgt tccatctgcg acattgatca
     2341 taaatcctgc atgcttttct gacacttcta cgccaccgat acgatagcct ttcaagccag
     2401 cttctgaaat taactgacct gcaaaatgcc cgactggacg cttaaagacc gagccacaag
     2461 atgggtattc caaaggttgc ttgagttcac gtaggtgcgt caagcggtcc atttcctgct
     2521 tgataacctg atgggttcct ggggctaggg caaatttaac tgacaagaca actgcaccag
     2581 actcctgaat agctgaatgg cggtaaccaa aagccaagtc tttagcagac agggtttcga
     2641 tttctccatc cttggtcaag accttacaag actgcaagat gtgagcaatc tcgccaccat
     2701 aggcacccgc attcataaag acagcaccgc caacgcttcc tggaatacca caagcaaact
     2761 caaagccagt caaactatga cggagggcaa tgcgagttgt ttcaatcaag ttagccccag
     2821 cttctgcttc aatggtatag ccatcaacag aaacgttatt gagcttgtca cacaagatga
     2881 caaatccacg aatcccacca tcacgaacga tgatattgct tgcattgcca agaaccatcc
     2941 aagggatatt ttcttggttg gcaaatttca caaggcgcgc caactcaaaa cgatttcgtg
     3001 gaaagaccaa ataatcagcc tctccaccta cttttgtata actatagcta tgcaagggtt
     3061 ccttaaaacg gatatcaatt ccttctaaga tttcaagcat tttttctctt acagacatgt
     3121 cactcttcct tttacaaaat tcattccatt ataccatttt tagagacatt tgacgaccat
     3181 aaaaatacct tgtttggatt ttgcataaga aaaagaggtt cccccctttt tatgattttt
     3241 tacaaaagat ttccttggtt ccataggcga ccagaacgag ctccagtgct agaatcactt
     3301 caaccaagac tggatttgtc aaccagccta cttggaaaag agatggtgcc agatcaaaga
     3361 aggcatgcaa gccataggct gctaggagat aaatccattt cttctggcga acagcttggt
     3421 aaacccaaac tgtcaaaagt aattggaaac caagcgccaa gattcgctca aaaccaagca
     3481 aataaatctg ccagaccgaa agtgactgaa tggtttttaa catattttca gacagtaatt
     3541 gcataacctg tggattctga gtttgaactg ccgaaagaac gatgtaaaga ttgagtaaac
     3601 taataaggcc tagaaaaatc aactccaagc caccatgccc taggccatag gccaaggcat
     3661 ctgccttttc caaacttctc tttttctcca accatttgaa gaaaacaaga cgagccgttt
     3721 cctcaaaaaa tgctgccatg gctaggccat agataatata gataagcgga tgatcttgca
     3781 agagggcaat actaccgtct ttttgaggat gcaaaatcaa gatatgcacc agtttttcca
     3841 aaatctgcga agagacaaag aaagcgactg cacccaagcc caagacagct agattaatct
     3901 ggtatttctt tttggtaaac caaatgcttc ctatcagaaa agctagcaac agcaacatgg
     3961 taataatgat atgaatggtc attttcttct cctattctgc cttttcaata tcttttttca
     4021 tctcgtcaac attgaactta gcaaacaagt attgacggtc ttggactggg aaacgttggt
     4081 ccaactggtc aactgctccc acctcgataa tgccttcctt gatgacaaaa tccatgacat
     4141 gtccaccgaa ggtcaaatca tctgatatga agtgcagatg gtagcctgcc acactgaccc
     4201 catggaaaat ctgaggcgtc cagaaaccaa caatagtccc cgcaacattg tcacgactat
     4261 attccggttg atgggttgcg atatcagcaa acttggtatc gggtgttgac ttaggaatca
     4321 tacgcacatg catatgtgaa aattcccccc gaatcttgat agagcggaaa agattttccc
     4381 catcataata agactcaatt cgttctttca attccttgtc tgtcatctca aagcgctggc
     4441 ggaaaatgac ctctgcctga tgcggtacca ctgcagcgta aggaataagg gcatctggtg
     4501 acacttccac aatttctggc tggtctcctg actctttggc ctgataagcc ttgccatcca
     4561 agacaatcaa ttccccatca atggaatcca aggttcccaa accaaggtca ccatgttcta
     4621 gcaattctcc tactgtcata gtaccaccat aaaggccagc catcaaggct ccaagagtat
     4681 tgtattgaaa taatttcact ggttcctgca cgttcttatc cattcacttt cttgtctgtt
     4741 attctataaa tcttactcct aagtatacca catttgcccc tagatgtgaa cgagagaaac
     4801 gctctagaca ttgccaagaa ggaaaaaaaa gggtacaatg taacaaaatc aagggaggtc
     4861 tggaatgaag aaacaaagca agtacaaaga ggtcgtttcc tatctgaaaa atggtatcga
     4921 gtctggacga tttccgacgg gtagtcgcct gccttctatc cgtcaactga gccttgactt
     4981 tcactgcagc aaggacacca ttcaacgagc cctgctggaa ttacggcacg aacaatacct
     5041 ctatgccaag cctcagagtg gctactatgt attagaacaa gggcaacatc aagacctaga
     5101 aatcgaggtt accgacgaac atgccagtgc ctatgacgat ttccgactct gtgtcaatga
     5161 aaccttgatt ggccgagaaa actacctctt caactactat gacaatcaag aaggattaga
     5221 agacctaaga caatccattc acaaactcct ctttgaccaa gctctctact gcaaggctaa
     5281 ccaactagta ctgacttctg gaacccaaca agccttgttt atcctctctc aaatatcctt
     5341 tcctagccaa gccaaggaaa tcttggtgga acagccaacc taccatcgga tgaatcgcct
     5401 cttgattgca caggggctgg actatcaaac gattgaacga ggcattgatg ggattgactt
     5461 ggaggagctg gaaggccact tcaaaacagg aaaaattaag tttttctaca ccattcctcg
     5521 atttcactat cccctaggcc attcctattc tgagcaggac aaacgagcta ttcttgactt
     5581 agcagccaaa tatagtgttt atatcgtcga agacgactat ctgggggatt tggactctaa
     5641 aaagggccag accttccact atctagatac agaggaacgc gtcatttata tcaaatcctt
     5701 ctcaaccagc ctctttccag ccttgcggat aacagcactc attcttccaa atactatcaa
     5761 agaagccttc gtggcctaca aaaatatcct agactacgac agcaacctca tcatgcaaaa
     5821 ggccctgtca ctctatattg acagtcaatt gtttgaaaaa aatcgtttgg ctcgcttgac
     5881 caatcatgaa tcttaccaaa aacaaatcga ggaaaggata actaaaacac cttgtcccct
     5941 tcctcattat cccctacacg atggtttatt gctagacctg agacagtatc ctaaaatcgc
     6001 cagtctcaaa cacagtcaac tgggcttgga cttctttgaa gaggcctatt taagcacctg
     6061 tccttatcaa tttgccaagg tgtccctaga caatctggaa aatgttttaa actatttaaa
     6121 agcagaattg gaatgacatc caactctgct ttttcttatt cttcaacttc agttaaactt
     6181 gctgcttttt caagatagct ttggtaagtt ccttcatcct taagtttttg gatgaccttg
     6241 tctaccactt ctttcaaatc atcactattt tttctaagag caacgacatt ggcgtcgccg
     6301 tccttcatct tcaagctgac agttgcgaca gctaagccag cgtttttagc agcataacta
     6361 agtgcaacag gctcatccat atgaacagca tctatttttc cagcctgcaa ttcattgact
     6421 gcttcaccca tattagttag ggaagttaat tgagcttttg gcaattgttc cttgaccatt
     6481 gattctggaa cagtcccttt ttgggctgca atattagcac tttctaggct agttaaatcc
     6541 ttgtattttt ccacatcagc cttacgaacc aagaaactaa tcttgttttc atagtatggg
     6601 attgaaaaat caaagacttc ttttctctcg tcagtagcac taattcctgc aactgctagg
     6661 tcagccttac cagtttgaag actggtcaaa acattgtcaa aactcatgct taagatttcc
     6721 aacttaaccc caagttcatc agcgatagcc tgagccatgt cgatgtctgc accgactacc
     6781 tggttctttc catcaaccaa tgattgaaat tcaaagggtg catagtcagg actggttgcc
     6841 acaactaatt tccccttttg cttaatggcc tcaacagctg actgagaacc attagaacct
     6901 gactggcaag ctactaagaa gaaacttgca agaaacttgc aagaaaatta cataaaacaa
     6961 atatccattt ttttgatttc ataaataaac aacctttctg ttaattttgt ataattataa
     7021 cgatatccaa gttacttgtc aagtgttttt taaattttta tctcaaaaat attttttcgt
     7081 tcaaaaaaag gagccatcag ttgatttcaa gctccttttt atacagaatt aaactatttt
     7141 atagttcgac aatcttacct gtttcaaagt agacaaccca ttcacagata tttttagcat
     7201 aatcaccgat acgctccaag taggaaataa cttggaaata atcacgaccc gtaacaatgg
     7261 cttctggatt tttcttaatc tcttcagtcg caaggtcacg gatagtttca aaatagtggt
     7321 taatttgctc atccatggag gccacccggt atgcgtcgtc aacagaacca ttaagataaa
     7381 gatcaagtgc tgcttcaaca acgcttttaa cttcacgtcc cattttttta atttcttcct
     7441 ctacagctgg gatgcgttct tcccccttca tacggatggt tgcctgggca atggctacag
     7501 cgtgatcccc catacgctcc acatctgata cagccttaag gacagtcaag actgtacgca
     7561 aatcttgaga gactggttgt tggagtgcga tcatttcaaa tgatttcttt tccagtttca
     7621 cttcgtattc atttacttct gcatcatctt ctatgacctc ttttgccagg tcacggtcat
     7681 gcgtgacaaa agcacgtacc gtacgattga tttgtgagag cacttcttgt cccatagcgt
     7741 agaactggtt atgtaatttc tctaaatctt cttcaaattg agatcgtaac atctttcatc
     7801 tccttatcca aattttcctg taatatagtc ttccgtttcc ttgtgttggg gatcaaggaa
     7861 catctgcttg gtatcattaa attcaatcaa atctccatct aggaaaaatc ctgtcttatc
     7921 agagatacgt gaagcttgct gcatggaacg ggttaccaga agcatggtgt acttgtcttt
     7981 tagaccatac aaggtttcct caattttacc agctgaaatc ggatccaaag ccgaagttgg
     8041 ctcatccaag aggatgattt taggactagt tgccaagaca cgggccacgc agacacgctg
     8101 ctgttgacca cctgacaatc caatagctga atcatataga cgatccttga cctcatccca
     8161 gatagaggca ccttgcaagg ctttttctac ggcttcatcc agaacctgct tatccttaat
     8221 tccattgata cgaagcccgt agacaacatt ctcatagata gtcataggga aaggattagg
     8281 ttgttggaaa accattccga tttccttacg taattcaacc gtatctgtac gcggactgta
     8341 gatgttgtga ccattgtaca ccacggatcc agttgtggtc acctctggat tgagatctcc
     8401 catgcggttg agagacttga ggagggttga cttccctgat ccagatggac caatcaaggc
     8461 tgtaatttcc ttaggttgga aagataggga aacactattc aaagccttct ttttattata
     8521 ataaacggac aggtctgata cctgtaaaat cgcatctgtc atacggtttc ctttctaacc
     8581 aaagtgacca gatacatagt cattggtgga ctgtagcttg gcattttgga aaatagttgc
     8641 agtcttatca tactcaatca aatcacccaa gtaaaagaag cctgtatagt cacttgcacg
     8701 agcagcctgc tgcatattat gcgttacaat gatgatggta aagtttttct tgagctcaaa
     8761 catggtctct tctagttgca tggtcgcaat cggatccaag gctgaggctg gctcatccat
     8821 taagaggata tctggcttaa cagagatggc acgagcgata cagagacgtt gttgctgacc
     8881 acctgataag gtcaaggctg acttgtggag atcgtcttta acctgatccc agagggcagc
     8941 ctgacgaagg gaggtttcta cgatttcatc taggacttgc ttatccttaa ctccagcacg
     9001 ttcatgcgca aaggtgatat tacggtaaat tgacttagca aatggattgg ggcgttgaaa
     9061 aaccattcca atgtgtttac gcatttcata aacgttgatt tctggacggt tgacatcaat
     9121 tccacgatag agaatctgcc cagttacttt agcaatatca atagtatcat tcatgcgatt
     9181 gagactgcgt aagtaggtag atttccccga ccccgacgga ccaatcaaag ctgtaatttt
     9241 atttctttca aattgcatat caatcccctt aatggattca tttttaccat agtaaacatg
     9301 gacatcctta gtagaaaggg ctactttttc ttcaggaaag gtaaggatat gcttctcatc
     9361 ccagttatat gttgacatgg cttctccttt aggcagcggt taatttcttg tgtagatagc
     9421 ttccgaactt acgagctcca aagttaaaaa tcaggataaa gatcaggagc acagcggcag
     9481 aacctgctga tacaatggtt ccatctggaa tagtgccttc actattgact ttccagatat
     9541 ggacagccaa ggtttctgct tgacggaaga tagagatggg gctagtcaca ctgaggatat
     9601 tccagttaga ccagtcaaga gctggcgccg attgccctgc tgtatagatc agagctgcag
     9661 cttcgccaaa gatacgacca gatgccaaga cgacacccgt tacaatacct ggaagcgctt
     9721 ctggaataac aacatgaacc actgtctccc agcgagaaat cccaagagcc agaccagcct
     9781 cacgttgggt atggtgaacg tgtttcaaac tatcctctac attacgcgtc atctgaggca
     9841 aattaaagac tgtcaaggcc aaggcacctg aaatgattga aaatccatac tcaaactgga
     9901 ctacaaagat caagtaacca aagagaccca ccaccactga tggtaaagag gacaagattt
     9961 caatacaagt ccgcacaaag ttggtaacag gacctttttt agcatattca gccaagtaaa
    10021 tcccagctcc catagaaaga ggtacagaaa taatcaaggt aatgaccaat aggaaaaagg
    10081 aattgtaaag ctgaatgcca atcccaccac ctgcttgaaa agcagaagac cttccagtca
    10141 agaaagacca agagatatgg ggcaagcccc gaaccaagat atagagaatc aaggaagcca
    10201 agattgtcac aatgatgcta gcaatcgtat agaggacagc tgttgcaagt ttatctaatt
    10261 tcttagcgcg cataattttt ctttcctctt tctttcgtaa tcaatttaat cacactgtta
    10321 aaaactaaac tcatcaagag cagtaccaag gccagtgacc agagaacatt attatttaca
    10381 gttcccatga cagtgttccc aattcccata gttaatatag aagttaaagt tgcagctggt
    10441 gtggtcaagg aagttgggat aacagctgag tttccgacaa ccatctggat agctaaagcc
    10501 tcaccaaagg cacgcgccat cccaaagacc actgcagtga aaataccaga acgggccgcc
    10561 ttcaagatca cacgccagat agtctgccag cgagtggctc ccatagcgaa acttgcctca
    10621 cgataataac gaggaaccgc acgcaagcta tccgttgtca taaaggttac ggtcggcaaa
    10681 atcatgacaa agaggacgga aatccctgac aaaatcccaa aaccagtccc accaaagaca
    10741 ctgcgaacaa agggaacgac gacttgcaag ccaataaatc cgtacactac tgaaggaatc
    10801 ccaaccagga gttcaatagc tggttgcaaa atcttcgccc cttttggtga tacttcggtc
    10861 ataaaaactg ctgcaccaat agcaaagggt gttgcgataa gggctgagag aatggtaacg
    10921 ataaaggaac ccaaaatcat aggaagggca ccaaattctt tactagaagg attccaagtt
    10981 cctcccaaaa gaaagtcaaa gatattcaca ccattgacaa agaaggtcga caagcctttt
    11041 tgcgctacga aaaccaaaat catggccaca aggatgacta tcaaagaaag acaggcaaag
    11101 gtcaaacctt ttcctaattt ctccagacga gaattctttg atggaagcaa cattttctta
    11161 gctaattctt cttgattcat tattgtctcc cttccaacac tgtcacagtt ccggcagcat
    11221 ctttttcaac cttcatttcc ttaatcggaa tatacttcaa tcctttgaca atcccttctt
    11281 gggtctcatc cgagagaaca aaattgagaa attctgcagc taactcattg ggctgcccca
    11341 atgtatacat atgctcataa gaccacaagg gccaattatt gctacttata ttttctggac
    11401 ttaagtcata gccattcaac ttcatgcttt tgaccgaatc atctatatag gtaagagata
    11461 aataagagat agctcctgga ctttttgata cgattgattt taccgctcca tttgaatcct
    11521 gctcctgact ttgcatggca gactgacctt ccataatgac agtatcaaag gtagcacgag
    11581 agccagagcc ggctgcccga ttgataacag agatgggtaa gtccttacca ccaacctctt
    11641 tccaattggt tacctcacct atgaagattt gacgaagttg ctctgtcgtt agattatcaa
    11701 catcaacctc cttattgaca atcagagcca agccagctac cgcgaccttg tggtcaacaa
    11761 gagcagaagc atcaattccg tctttttcct cagcaaatac atctgagttt cctatatcaa
    11821 ctgccccaga ctgaacctgg gacaagcctg taccagaacc tcccccttgg acattgaccg
    11881 tttttccaac atggatcgtg ccaaattcat ctgccgctac ttcaaccaag ggttgcaagg
    11941 cagttgagcc aacagccgtt atggattctc cacgatcaat ccagctagca cagcctacta
    12001 aacaagccgt cagccaaaaa gcgataagag acagagcaag cttttttctt tttttcactg
    12061 tttttctcct cgaaaataat tatgaatact gtgaattttt taagtagttc tttatgagtt
    12121 gacgcatgaa ttcttaccaa atttctgcgc aattgattat ttatataata taggctatat
    12181 tactctttcc taacctcctt ttttcatatg tggataaaat ctcttgtcta tcccttcccc
    12241 cattgtcacc cattatagtc atttcgtgtc tctttttccc ctttttaatg caagggaaat
    12301 tactctcctt agatgataat ctaaaagcta gaaaggtatc tcaaatctct ctactctccc
    12361 agactagttt acaactaaaa ggaaaagatt ctattttatg agaaatctag tttacaagcg
    12421 gtaagaacgc taataactaa acttcttgta ctctttgaaa atctcttcaa agcagtgttt
    12481 tgagctatct atggctagct tcctagtttg ctctttgatt ttcatcgagt agtaaaacta
    12541 catgtgatgg caatcaagat atcaagaatc atcctactaa aaaaatccat actttcacta
    12601 taacatagaa taagatattt gactagcatt ttcatttgaa tctgaggcct tttggaaaat
    12661 aatttttcaa aacatttcca gtaacctttg caaagcccaa gccattgcct ttaaccaaaa
    12721 cttggtacca accatttggc agactttctg ccagctgaac ggtttctcca gccgcatact
    12781 tgacaaactc ttcttggcca atttcaaccg actgttcgac ctgactcggt ttcaaggcta
    12841 aaccaagagc gaaactgggc tcaaagcgtt tcttcttaaa agtacccaga tgcagtccat
    12901 tgcgagcaat cttgagcttc cctaaatctg gcaaaagttc tggcaagaga taaagctggt
    12961 ctccaaaaat ctgcaagata cccggtagat tgaccttcaa atggttttgg gcaaattcct
    13021 gccacaaggc aacttgttca cggctgaggt tactcttact tgccttaaat ttaggagctg
    13081 gattgttacc cttaaactgt agatgggcaa caaactgacc ctctccctta aactgatgag
    13141 ggtacatccg agccgtttct ggcaggtcaa taccagctac cattccattg atatgctcta
    13201 ctggcaacaa gtcaaaatca tactcttcca gcaaccaatt gacaatctct tcgttttcct
    13261 cgggtgccca ggtacaggtc gaataaacca gacgaccacc ttcagctaac atggtcactg
    13321 catcctccag aatttctctt tgcaagctag cacattgact cggataatct aagctccaat
    13381 agtccatagc atcaggttgc ttacgaaaca ttccttcacc agagcaaggg gcatcaagaa
    13441 cgattaagtc aaaatagcct ttaaagacct tgaccaagcg gtcggcagat tcattggtca
    13501 ccacgacatt tgtcgctcca aaacgctcca tgttttcaac caaaatctta gcccgtttgc
    13561 ttgaaatttc attggaaaca agtagcccct cccctgctag ataggctgcc agttgagttg
    13621 atttgccccc cggtgcagca gccaagtcca agaccttcat accaggactg ggttgggcta
    13681 cttgagccac catttgagca gcaggttctt gcgaataaac taaacctgta gcatgctcag
    13741 gcgatttccc tgaaaccttc ccatagtggc cccaaggggt ttgagtaatg gcatcagaaa
    13801 aggaaagttg ctcttctttt aagggattga cccgaaaggc cgaaaccgct tcctcctcaa
    13861 aagaggcaag aaaatctctt gcctcatctc ctagtatttc tttatatttt tcaacaaatc
    13921 cttctggaaa tttcatttaa gttcttttcc tttcgtaaat ataggactga atttcctcct
    13981 gcatctcaag aggcaccatc atgaccggct gtctggtttg aaaatcagga gcttcaccaa
    14041 aaagggtcac aacccgatag cccagacttt cccctaaaat actagctgcg gcataatccc
    14101 atggttgcag ataggtgaga taggtcaaca aacgccctga caaaatcttg gcaaaactaa
    14161 tggccgcact tccatagaca cgaacaccaa gaaccgctcg gctcaaatca gccagccccc
    14221 attcattggt ttccagcata ccactattcc ctgcaatgag aaaatctcca agtggtttag
    14281 ttttaaaaga agctaggggc ctatcattta gacaaactgg aaattcccca ccaccgtggt
    14341 aacaatcccc tttgaccaca tcataaatca gaccaaactg tccctgacca ttttcaaaat
    14401 aagccatcat aacagcaaaa tcttcctgct gggctacaaa attattggta ccatcaatgg
    14461 gatcaatgac ccaaaccttg ccctcttgaa ccgaggctcg cagacaacct tcttcagcac
    14521 aaatcttatc ctcaggataa cgggacaaaa tctcaccaac caagagttcc tgaacttctt
    14581 tgtccagtct ggtcaccaaa tctgttggag aggacttggt ttcaacacgc aagtcttcct
    14641 gcatatggtc aagaatgtac tgacctgctt tcttaacaag ctctttagca aattcaaatt
    14701 tactttccaa gagaaatctt tccttcccct ttttctttgg cagcctgaac tgctcggtaa
    14761 agtgaatagc cactaaccgt ttcaaattct cgtcccaaac gtttctcttc gctcttgctt
    14821 ggcacgaccg ctttgaatcc cttataggag tccagtaact ttttagcctc tactttgcct
    14881 tcataggcag cttcaacatc attaaaaaaa gaaagcactg aagcaagttc ttcagtgctc
    14941 cacgacaaat ctagtgggta actatactgt ttgttcatta actaatacca gctctcattc
    15001 ttgcttcttt tagttcttgc ttacgataac tacgagggag aaaagcacga atctcatctt
    15061 cattaaaacc gatttgcata cgcttggcat caataataat tggacgacgc aaaagactag
    15121 gatactgctc aatcaaatga agcaattccg ataccgaaat actctctaca tcaatattca
    15181 atttttgaaa aatttttgaa cgagttgaaa tgatgtcatc agtaccattt tcggtcaagg
    15241 aaaggatttg ttgcaattct tttcttgtta aaggactggt cataatattg tgttccacaa
    15301 agggaacctt atgtttttct aaccaggcct tagccttacg acatgatgta cagctcggtg
    15361 atagaaatag tgtaatcatg cttttctctt cttatctata ctttgctact tctattatac
    15421 aaaaaaataa ggcgcttgac tagggatttt tagaaaaaaa agcctatttt tcaagaaaaa
    15481 taggctgttt gcgaacgatt gacacaattg gatttggtta attcactctt aacgatggtt
    15541 ttaaacgata tatattttta tatatgcaaa ttaaaaacat ctttcatttc atttcctacg
    15601 acttttcaga cacagatagc caaagaagct ttcatagagg gcaaaaaaga ggaggaaggc
    15661 atgaagaaag aaggtctctg gcaaaatcat aataacagga tccttggctg gatcaaaaag
    15721 ccaggtatca tctcccacaa agagaatttg atggaaaaga gtaaagaatt ggtcaaaacc
    15781 aatcaaaact cccccaagtc caatcatcac aggtaagact actagagtca ggagactttt
    15841 tcgataaaga gacaaaaagt cctttttcac aattctattg acaaagacat agaaacttgg
    15901 cagtgtcact agagctacta gctgaaccaa atgaaagaga ttcttgacca ctgcgaaatg
    15961 gtgcagacca gctgctgacg aacgaaaatc aggcatctgt aagacctgac taaaaggatt
    16021 ggtcagataa ttcatcaaga tatgaaaatt gtattgaatg gtttctggtt ttagatagac
    16081 tcgattcgtt aagtttagcc actgaatctc cataggatag aaaatccaag ccagataaat
    16141 gggcagaagg attgagaggg agaggagaaa gagcatagag ccccaaaaga tcaatttagt
    16201 tttcatcaaa atcccactcc gcaaggctag aaaccacatg tgtcggtgcg attggcaggc
    16261 cagctacttc ttctgcctta gtaaaacctg tcgtcaccaa gagcgttgga atgccattgt
    16321 caatcccagc ccggatatca gtcaaataat tgtccccaac cataattaac tcttcacgtt
    16381 ccaaacctaa gtgctcaacc gccttgtcca taatgatggc attgggtttt ccgatataaa
    16441 ccggcttcac tcgtgtcgct acttcaagca gcgtaatcag ggagccagca cctggcaaaa
    16501 gaccacgttc cgtcgggatg ttgaggtcag gattggttcc gataaaatgg gcaccctttt
    16561 gaatagcaag agttgctgtg gcaaattttt catagtcgac ttgccaatcc agaccaacta
    16621 ccacgtaggc agggttttcc ttgtcttcca cataaccagc cgccttgatg gcttccttga
    16681 gtcctgcttc tccgacgaca tagacggtct tttcaagccc caaatcattc atatagtcga
    16741 tggttgccaa agtcgctgtg tagacagtcg ataggggcgt atcgatatta aaattctgag
    16801 ccaacatctc cttaacactc tctggagtgc gagttgtatt gttggttaca aagagatagg
    16861 gaatgtcccg cttttgcaat tcatgaacaa aagtctctcc agcagggatt cggtctttcc
    16921 ccttataaat ggttccgtct aaatcaatta aatagccttt atatttcatc tatttctccc
    16981 taagcctttt ttatttcttt ccaagtaatg attgcttggg cattgataac cccatcactt
    17041 gtaatttcat gcttgctttc cagtccagtc cgttcaacag ccgatgtaat caccccacct
    17101 ggtcgaactt ccttgacata cttgaggttg attttcttgg gaatatagtg ggtcaaaaaa
    17161 tccgctccca tgacctcaaa aatccagtcc aagtatttac tgttattgac atgaccattc
    17221 atatccaagt cgtaaaaacg aacatggtaa tccttgctga tcggctcttc caaggactca
    17281 tacttcggtc cacggataag ttttttatca aaatcagact ggtaaggagc cacaatctca
    17341 ggttcaacag catggacttt tcgactgtcg cggtccatga gaacaaaggt cgccatcata
    17401 tggatgagct cctgccccgc ttcattataa atagtaaagc gacggtagca aaaaagtcga
    17461 ttgtagctca aggcttccgt ttcgatggta atttcttccg caaaacgagg caaacgaacc
    17521 acctcaatat catattctgc gataatccag accagattat agtcttccaa aatggcctta
    17581 tcactaactc ccagttcaat cgactgcatc cctgaaactt gcagtgacag caaaatcaca
    17641 tctggaagtt tgatatgacc gttcatatca gccatatcaa aaggaatttt cattttcatt
    17701 tgataagtta agcccatgat cctactccaa aataaatcgt tctgctacag tatctcccaa
    17761 aaagagacct ctctttgtca tgcgaacgtg gtcaccctca atctgcatga ggccttgttg
    17821 aaccaaatct ctgacaattt ctccataaag tccagcaaaa gactgtccaa atttttcctc
    17881 aaatcgcgcc atggaaaccc cggatttctt gcggagtccc aagaacattt cttcttccat
    17941 ttgctccttt tgactcaggt gatcttctgt aatacaagca ttgccttcct caaccgcact
    18001 gagataatga cgaatgggac catgattttt ataacgtact ccattgacat aaccagatgc
    18061 ccctgcacca ataccatagt attcagcatt gtcccagtac atgagattgt gacgactttc
    18121 aaagccgggt ttggagaaat tagaaatctc ataatgctca aaacctgctc gctccagctc
    18181 tgcaatgatg tactcaaaca tctccgcttc tagttcctcc ttaggcagag gcaatttccc
    18241 acgtcgcatc cggttcataa agaccgtatg gttttctaaa atcaaactat acaaactcat
    18301 gtggggaata tccagtccaa tggctttagc cacattttcc tttacttgct ccatggtctg
    18361 accaggcaga gcataaatca aatcaatgga gatattgtca aaaccagcca gtttcaggcg
    18421 atcgatattt tcataaatat ccttctccaa atgactgcgc ccaatttttt tcaacatctt
    18481 atcatcaaag gtctgaacac ctagcgaaac acgattgaca gccgaatttt tcaaaacagc
    18541 tatcttatcc gcatccaaat cgcctggatt ggcttcaatg gtcaactctt ccaagacaga
    18601 caagttcaag tttttagtca agccattcag taacacctcc agttgcggag ccgacagggc
    18661 tgtcggtgtt ccaccaccga tataaagggt tgacaacttt tcaatatcat aagaacgaaa
    18721 ctcttccagc agatgctcta aatagctgtc gactggctga tttttgatga agacctttga
    18781 aaaatcacaa taataacaaa tctgggtaca aaatgggatg tgcacatagg ctgacgttgg
    18841 ttttttctgc atagtaatta ttataccaca aagactagat tccagataaa aatcaccatc
    18901 cccagataca tagtccgtcc ggagatggtg atggtttatt cttctgttat atcaatcaca
    18961 atctcttctg agtcatcaag agcttcggct ttttcttgcc attgctcctt gagattattt
    19021 aattgatttt ttgatgcttc tgtcgcttga aaagcatagg atttagcttg agcaagtata
    19081 ctgtccacag tgatttcacc tgactcaacc tgttcttttg ttttcagaac aaaatctgta
    19141 gcctgctcct taacttctgt cagtttttca cagacttgct ccttggcata ctccggatct
    19201 tctctcaaat catctagaaa atcttgagcc tgactgcaaa cttgtttgcc cttatcactt
    19261 gttaaaaaca aggcaagagc tgcacctgaa accgttccta aaaggattga ggataattta
    19321 cccataagga ttctcctttt ttattttttg aaaaatttac ttgcaagacg aagagctgac
    19381 agacttgcac cagtcttgag tgtttttgaa ccagctgatg aagctttctt gctcaagaca
    19441 cgcgcatggt cattgaggtc tgaaacagat agagataaat ctgcaacagc actgaagagt
    19501 ggatcaatcg tagccacctt gacattgata tcatctgcca agacattgac cttagccaac
    19561 aactcattgg tatgatgcaa ggtcacatcc acatctgaag tcaaggtttt aatcgtcttt
    19621 tctgtttcat cgatgacacg accaagcttt tgtacagtaa tgatcagata gaccaaaaag
    19681 acaatcaaag ctagggcaac aagaatatat gcaacttcta acatttagtt ttcctcctct
    19741 gtaatatagt aaggggcctt ctttcgattt tgataaataa cgatcattat accgagaccg
    19801 ataaggacaa ctgacagcca ttgggacact cgaaggccga agaacatgag actatctgtt
    19861 cgcatacctt cgatgaccat acgaccgaaa ccataccaaa tcaagtaaaa ggccgtgata
    19921 tgacctcgtc tgagactctt ccatttccgt ctaaaaatca gaatcaaggc aaagccaagc
    19981 agattccata gagactcata aaggaaagtc ggttgacggt agctcccctc aatatacatc
    20041 tggtcacgga taaagccagg tagataatca agattatcca ctgttgcacc ataagcttct
    20101 tggttaaaga aattacccca acgccccaaa ctttgagcaa tcataacgct aggcgccgca
    20161 atatctagaa aatcccaagt attgatgagt ttacggtcag caaagatata gagcacaaga
    20221 gccccagtta tcaaaccacc gtaaatggcc aaaccaccat tccaaatggc aaaaatctct
    20281 cctaaattct gactatagta atcaaatcgg aaaataacat agtagagacg agctcctaaa
    20341 atagccaagg gaaaggctac taagataaaa tctaaaatat cgtctggtat gatcttcttt
    20401 ctaggtgctt ctttcatggt caaataaacc gcaagaatca agcctgtcac aatacataag
    20461 gcataccaac gaatggctag gggtcctagt tgaatagcaa ttggatcaag cattttgcac
    20521 ctcatttcga gcgattagac ttgtcagtcg ttcgtcgaac aaacgggtcg catcaaagcc
    20581 catttccttg gcacgataat tcatggcagc tgcctcaatc acaacagaga tattacgacc
    20641 tgttttaact ggaatacgaa tacgaggaat ggctacgcca gaaacttcaa gttcctctgc
    20701 attgtttcca agacgatcaa aggtcttatg tgtatcgtaa ttttccaaat agacagcaag
    20761 ctgaacctgt gaagaatcct tgacagcact cgcaccgtag agactcataa catcgataat
    20821 accaacccca cgaatttcaa tcaagtgttt caaaatttca gctggttcac cccagagagt
    20881 aatctcatcc ttggcaaaga tatcgacacg gtcatcggct accaaacggt gaccacgttt
    20941 gacaagctca agacctgtct cgctcttacc aattccacta tctccctgaa tcaagacgcc
    21001 catcccataa atatccatca agacaccgtg cacactggta cgttctgcca aacgagaatc
    21061 cagatagcta gataactctc cagataaacg actggtagct gcacggctgg ttaaaatagc
    21121 aatcttacat tctctagcag cctttaacat ctcctctgga accaccaaac cacgggcaac
    21181 aatgactgct ggtgtctcag gtagaaacat ttttttcaaa acttcataac ggctgttgga
    21241 aggcatgctg atcagataag accactcctt catccccaaa agttgaatcc gctctggtgt
    21301 atagtagtca aaatagcctg tcatttcaag accaggtcgc gtaatatccg ctatattgat
    21361 ttccttttca agcaattctg gttcaccata gacaatgtct agtctaagct tttcaatcac
    21421 ttcttttact aaaaccgaca tcatttcctc cttcaaatga gttcttctct ctattatatc
    21481 aaattgtagg aggaagtttc agatttttgc aggctttgga gtatttattt aaaagaaaaa
    21541 ggactagatt tctctagcct ttcattccaa ttagaatttt ttacgtttac gagctacttc
    21601 tgatttacgt ttacgtttta cagaaggttt ttcatagaat tcacgtttgc gtgtttcttg
    21661 aagagtacca gctttagtaa ccgcacgttt gaaacggcga agtgcgtcgt caagagattc
    21721 attcttacgt actactgttt tagacatttt tttcactccc ttcaagttca atatctattt
    21781 cattctacac gtaaaaggaa taattgtcaa gcaaaaatgc ggtttaattt tgattttttc
    21841 ttccatttat acaagagttg aaagcgttca atagaacatt gcttttttat ttttcgagta
    21901 agctaagcgc ttcagcatct gcgatgatgg ttacatcagg gtgattttgg aggctacttg
    21961 caggtaggtt ctcagtcact gggccagata ctgttccggc aatggcttct gctttcgact
    22021 caccgtaagc aaaaagaata atagacttgg catccaaaat gtttttaatc cccattgaaa
    22081 tagcttgggt tgggacgtct tcaatcttgg caaagaagcg tgcattggct tcaatagtag
    22141 actggtcaag ttctactaga tgcgtttgac tgtcaaatgg agtaccaggc tcattaaagc
    22201 cgatatgccc attgcgacca attcccaaga tttggaggtc aactggatgg tcagccaaaa
    22261 tttggttgta gcgttcaact tcagcttcag cattgtcctt aacaccacga ggcaagaaac
    22321 tttctttaaa tggtttttgg ttgaacaagt tttcttgcat gaagtaacga taagactgtg
    22381 gattgtcccc atcaaggccc acatactcat caaggttgac actggttaga tttgaaaaat
    22441 caaggtcact ctcaacaatt tccttgtaaa attcaagtgg gctacttcct gtcgcaagtc
    22501 ctagagtttg agctccatta gccaattttt ccttcaaaat ctcaaaagca acttttccac
    22561 cttgaacttg gttttcaact ttaataactt tcatcttttc atcctccatt tctgtctata
    22621 tttattatat ggtatagacc aatttttgtc aagtgaaaac gatttaattt ctaaaaaaag
    22681 agcgtccaaa cttgaaacgt gttataatgg ataggattat aacttagaaa gaatgaacaa
    22741 atatatgaat acagctgatt ttgatttcca cttgccagag gaattgattg cccaaacgcc
    22801 ccttgaaaaa cgtgatgcct ccaaactcct catcgtcaac cgtgagacag gagaaatgca
    22861 agataaacat ttccactcta tcattgatat gctggaacct ggtgatgccc ttgtcatgaa
    22921 cgacacccga gttctccctg cccgcctcta tggtcaaaaa atggagacag gaggtcatgt
    22981 ggaacttctc ctccttaaga acactagtgg agacgagtgg gaagttctgg ctaaacctgc
    23041 caaacgcctc aaggtcggta ctcgtatcag ctttggtgat ggccgcctca gcgctgtcgt
    23101 tacagaagaa ttgacccacg ggggacgcat tgtccgcttt gaataccaag gaattttcct
    23161 agaagtcttg gaaagtctgg gagaaatgcc tctgccacct tatatccacg aaaaattaga
    23221 tgaccgtgaa cgttatcaaa ccgtctacgc caaggaaagc ggctctgctg cagcaccgac
    23281 tgctggtctt cacttcacca aagaactgct ggcagaaatc caagctaagg gtgttcatct
    23341 agtctatctg actctccatg tcggactcgg aacctttaga cctgtttctg tggataatct
    23401 ggacgaacac gaaatgcact cagagttcta tcaactttct gaggaagctg ctgccaccct
    23461 tcgctctgtc aaagaaaatg gtggtcgcgt catcgctgtc ggaaccactt ctatccgcac
    23521 cttggaaact attggttcca agtttgatgg gcaaatccaa gcagattctg gttggaccaa
    23581 tatctttatc aaacctgggt atgagtggaa ggtcgtggat gccttctcaa ccaacttcca
    23641 tctgccaaaa tcaactctgg tcatgttggt ttctgccttt gcaggccgtg aattagtctt
    23701 agatgcctac caccatgcca tccaagaaca ctaccgcttc ttcagttttg gtgacgccat
    23761 gtttatttat tgagaaagaa tttctctaat tcttctaata ccaataaatc gctaagatat
    23821 tatttcaaag aacatctaca attgaaactc tagctagctg tagaagacgc ctagtacatt
    23881 gaaattaaaa tgcttccccc tagcttcgaa aatattgcca tagattgcgt tgactctcca
    23941 aattgattca tctatatttt atttcagctt cctatatttt cttcgctgtt tgtaaatcaa
    24001 aatgcaagac acatgagtag caccatattt gttactctta tctgtcctct caagagacta
    24061 ttatgagtta tttcagaatc attcactact ttgaccctga ctctccttag tctcaaaatc
    24121 aaagacttat actcttcaaa aatctcttca aaccgcgtca acgtcacctt ggattatata
    24181 tgtgactgac ttcgtcagtt ctatctacaa cctcaaagca gtactttgag caacctgcga
    24241 ctagttttct agtttgctct ttgattttca ttgagtatta aacaaaaagt gaacaaatct
    24301 gaattctaat gtacagaaga ctaggcttgt tcactttttt atagtcgcta taagatgacc
    24361 ttatctatag ctttttatat ataattatat attcagacat actattatca attttgtcgc
    24421 agggaggaat ctgttaacgc acccattcac cattatcatt gactctatag ccatctatac
    24481 ttgtattgac cgctaactca cccgatgcat ttacataata ccatttacca ccaacttgga
    24541 accattgatt gactttcata gaaccgttgc tgttgaggta gtaccatgaa ccattaactt
    24601 gtacccaacc tgttgccatg gaaccatcag tattataaaa ataccacata ccattttctt
    24661 gtttccagtc tgttgttgga gcaactgctt tagctggttc tactgctaca tctgttcctt
    24721 ggttagatgt aacagataca ggatacgaag gaatagatga ttgctcagga acaacaactt
    24781 tttcaggttc tctcgtccct ctccttatac gtctttttac catctcttta gtaatttgac
    24841 gagaagtagt ttcttcaatt gttccatcac gttcatctac agtatagatt gtagtaagag
    24901 taatttacca atttctccta cttcttctac ttcttgactt ttatcaagag ttgggccatc
    24961 gagatattct gtttcgattg gaatttcttg gacaagaact tggggcttgg ttcttttttt
    25021 aacaactctt gtttgagagt ctttttttga cttaaagtac tctcagttac ttgtccactc
    25081 tttccatcta cattataagt tatcgttgta actgttttcc cattctttcc tagagtaatc
    25141 tcttgctcct gtcctgcaga aaggtcattg tctgcttcat atttagtagc aaatggaaca
    25201 agaacttctt caaccttgct tttagctgga actttgataa ctgtatccgt ggcttctttt
    25261 ctatcaacag taacctgttc ggtaacataa ccagtctctg gattaacatc gtaggtcctt
    25321 gtcgtagtta catagccatc ctctccatca attgtaacag gattttcact acggtctttt
    25381 gtttcatctt tttcataacg aattcgcgta cttgaaattt tcttggttac taccttaggt
    25441 ttagtcgcta cttttacaat aatatcccca ttgtcagcgt catcatactc tattccctct
    25501 tctttatctc tagtatcatc tctgacatat tgaatcccat cagcagcatg aacaaaactt
    25561 gtattcagat tcctcctaaa aataaagtta gcccgattac cgcagaacca aaaatctttc
    25621 cgagtttacg tattgcatag cgcttattag tattagattt tgccattaca tcctacttct
    25681 agtatagcat cttttctatc aaacgttaaa caatatactt tatatataaa atagacttag
    25741 aatgatatat tgattattga actaacactt taactatatc gtaatcaatc tcatatataa
    25801 aggattgcag acatcttatc taaatacatg ctaatatatt tagatacaaa cattccaact
    25861 tgataatttt cactcatctt tcatcattcc ttatacaact atgcagtata aatagaatag
    25921 ttttctcatc agaatgagac tattttaata ttagataatt tgatagaaaa aacatgaata
    25981 aaattggttg aatttaattc cctaactcga tagaggattc tattttaaat ttaacaacag
    26041 ctaggattac actataaaaa gtacattacc acctgttcgg ctggagaatc tagtcgatta
    26101 gctccctctt agttacaagc ttcaagcgat tttttaacta acactaaacc agattaaaga
    26161 aggaactaga acatctgtct tgtactaatc aatatgctat tttaaagttt caaataaact
    26221 tggaatgcta attattatat ttacaataaa tagttgactt cgatagaaac agaaaataga
    26281 attcaacatt cttccctact tataccataa taaataagat ccgcaagata gccttttctc
    26341 tctacaccat taacaatggt ttgtagatag gacattccag ccttttccat gacacgacct
    26401 gaagctgggt tgagactggc ataacgtgct ctgacctttt gaaaacctgc ttgagtaaaa
    26461 caaaagtcca agatagcttt caaagtctct gtcatcatac catttcccca gtaagccttg
    26521 cctaacacat agccaatttc acagcttaaa tcagcctcgt ctatcttaac aatgctgata
    26581 tctcctatta cttgctctgg gttttctttt agacaaatgg cccatttata atagttgaga
    26641 ttagtatagg aagcaaccca attgcaaatc gagtttcgag tgatttcgac atcaggatgg
    26701 ggatcccagg taacataggt cagattctca gcggatgaag cccaattttg aaacatggct
    26761 tctgcatcac tctccacaaa tcttcttaaa atcaaacgtt ctgtctgtaa tatttgcgta
    26821 ccgatagatt tcatgatgct acctcacttc cttatttcta tactcgtagt aaaaaggctc
    26881 aactcagtaa cagctagaaa acgagtttgt cttctaattt cttgacgcag ttgctgcctg
    26941 gtttgaaatg cgctctagca agctttttca aacctagtca tcgttgcagg ggtaagacga
    27001 tgaaatcgaa ctcttcgagt tactgaatct gcctcatttt cttatttcta aactcggggt
    27061 tcaagatccc ccagaccttc tctcactttc ttatttcaag atgagaggct gaaaacctcc
    27121 agtggaggtt tttcttgctt tttaatttca gggcaagaag ctaaaaaggt cccccggacc
    27181 tttttactcc caaaagtcat caaatacggt gatgggtaag tggcgtttgt gttggccttt
    27241 gtgccaccag ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta
    27301 gtcgtcaatc tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc
    27361 ttcttctagg tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg
    27421 caagagctgt tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc
    27481 gtcaccaaac ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac
    27541 cgctccgcta tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat
    27601 attccccttg ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc
    27661 atcagctgat tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc
    27721 tttttgagca tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt
    27781 gtagctatcg tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgtcc
    27841 tgccaaggtt gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg
    27901 ttttttcaga tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat
    27961 cactggtttg acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct
    28021 tcaccaaggg cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca
    28081 cgcgccaaat ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac
    28141 ttgtcaaatt ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact
    28201 aatattcctt ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc
    28261 ttcttgatgt atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc
    28321 acaccatcat aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc
    28381 cacacctgct tcttacctgg cgtagaaact ttttcagcat tattagacag cttaatcgta
    28441 ttgcgcatct gaccagtttc atcttcgatt gcaacaatct tgtaaaccgc cccaagagcc
    28501 ggctggtcat aggctgtaat cagcttggta cccacacccc agacatcaat cttggccttt
    28561 tgcatcttga ggttaaggat ggtattttca tctagatcat tagaagcata aatcttagcc
    28621 tctgtaaatc cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc
    28681 ccagagtcaa tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga
    28741 atggcagctg gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt
    28801 ttgtgggtcg cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag
    28861 gcatgggcat gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgcta
    28921 gttccattgg cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct
    28981 tgagcccgac gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga
    29041 gctgccttcg tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc
    29101 aactgacatt gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa
    29161 tccccttctt gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag
    29221 aacgccccat gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag
    29281 tcttcaagat agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa
    29341 ggctgttggc ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag
    29401 taaacctgca tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga
    29461 tacatacttt tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt
    29521 attccaataa attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag
    29581 ctattctcca ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc
    29641 atagctctta agaccaagat tgccaataaa gatccacgga aggtaaatga tataagtaat
    29701 gacccaagca gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa
    29761 ttgataattc tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa
    29821 aatcgtaaaa tgaaaacgac tatagtaggt cactcccaga taacgggcac gattgaaaaa
    29881 gtaaaatgtc cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc
    29941 taatactgaa atgatataag ataggagcga caaagcgatg cagatataga aactttcaga
    30001 gcccgcttta ttgaacagtt gttcttctct ttcgtctagt aattgataat aataaaatct
    30061 atttttcatc ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa
    30121 tggactggca gagcgagaga ctgggattgt atttccccgc ttctatcaaa ccaatagtct
    30181 ggcgcgtcac cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag
    30241 ctaattttaa ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct
    30301 actcttaaaa aatccaaaac caacacaagc tatcagctat ttattataac cccattaatt
    30361 tgcactccag tattatcttc agccgaaaat cagtatttta ggttgtttga aataaacttc
    30421 ctagtttact cttttatttt tatttagtat tagctttagt aggatctttt aaacgagttt
    30481 ttattgctta tatttcttgt ttagtttagt tggtttcata tcactattat ataatgcttt
    30541 tggaaatgag cctagtataa gtcaaaaacg tgttgaatag tgaaagcagg agcataccaa
    30601 gatgactgat ttttttattg tattttaggt atgcaaaata atactaaatg aaactaaaat
    30661 gaatacttct tgcttttctt gagagtgaaa aagtacaata aaatgattgt agtgattagc
    30721 acaagatact gactaataga catcgtattt gaagccacaa atacaggtaa agaataaaaa
    30781 aggaagaagt tcaattgctt tgataaacaa atcattacta gtattcatca tcatcgtatt
    30841 taatatatta gagataaaga gtagtaaagc tactaaaata ccaaatacca agccactttt
    30901 caatttgtat aaatagaaaa tgtaagataa tagaaaataa aacaggacta acaaaattgt
    30961 attgactaca atagctacta taaaatttaa tcctaaatca cctggaatac ccaatttact
    31021 tactatgact agtaacacaa tgccattcaa agcataaata atggaaactg agatagcata
    31081 tagaaaatta gacaagacgt aaatcatccg attcttctgt ttatttaatt tcatgattat
    31141 aaccttcctt tattttgaac gatttaggta aatatcttta agcgtctctt ttttagtttc
    31201 aaaatcaact actttaatag agttttcgtt aaaaaattta aaaagctcac tattttgaat
    31261 attcccagac atagtaattc tcaatccctc ttcctaaaca atatcccaaa attcttgttt
    31321 ggtaatgaaa atgtctctat ctgtagctga tgaaaaagct atctcaaaca agaaattatg
    31381 actatctttt cctacttttt gaaatgtcaa aagcccgttc tccaagaaaa gaactctctc
    31441 acaaatttct tcaatgtctt ctaatttatg actcgatatt aaaattccca cattttcatg
    31501 taaagctaat ttttttagaa ccgctaaaac tatttgtgat gattcaatat ctaaaccatt
    31561 agtcggttca tctaaaatca atatatcagg ttccgtaacg agagttagaa gcaaagctaa
    31621 tttttgtttt gtacccaaag aataggtctt tactttttta ttaatagact gagtcaaatc
    31681 taactcttgg atcaaacatc taaatctttc ttgattgtag tcaacaccat ataaatttga
    31741 caaatatttt aaattctcta aacctgtttt agataaaaat aattttggtt cttcgattaa
    31801 atacccaaca ttatcactgc ttataatatt acctgaagtc ggttgattat tctgaacaag
    31861 aattttcatc aacgtactct taccaactcc atttctccct gctagaccaa caatttcacc
    31921 cttgttaagt gcaaaattta tatctttgag aatgattgaa tgaccataat gcttacttac
    31981 attttttatt cctccattaa tattattggt tttctctttg attctcatta attttaaaaa
    32041 gttgcgcctc tttttaacaa tattatatca tatatctaac ttaatgcaat atataaatgt
    32101 cattttgtga aattttatta acaaaaaact ctctacaaca aaataataga gagttttctg
    32161 cttattaatt tttttcaaaa tatctaagac atcacttctt tgtttaattt gataggcttt
    32221 gatacctgag ctccgacttt atcacttaaa aaataaaaaa gacagctaat ctcttgcgca
    32281 tcaagggatt tcgccattct ttaatctcgt ttaagtgttg tatatggagc tttgcataat
    32341 tttttaaaac taaacaacta cattaagcac gaactgtgac gctggttcca tcttccttat
    32401 aaagattgat aagcccctct ttaagagctc gaaccatgtc tccagcttga acaggttgtg
    32461 ggactttaat agtcaatagt tccattggat ttggagcgcg gtcgatttta ttgcctttgg
    32521 catcatgcaa atcttcaata taggtttcaa aatgacggaa acctggacca taaaactcaa
    32581 cttggtcccc ttcgttaatg acgttccgtt gacgaatggt tgctgtttgt gtcgcatcat
    32641 cataagaaat cacttcagcg acaaacttgt actcaggaat tttacgacga gcaccaaaca
    32701 actgctcatt ttcagatggt ataccatagt aaaatcctgt agccagttca cgttgggcaa
    32761 ccttccacat ctcgtccacc aagtcttgtt tgatagcttc aaacttttca ggactttcaa
    32821 gataggcatc cacagccgcc ttgtagcagt tggttactgt tgatacgtag tgaatagact
    32881 ccactccata cgtccttcga tttttagatt gtccacacca ttttcaatca tatctggaat
    32941 gtggtcaatc atagacatgt caacggctga cattgaaaat tcttctggaa tctcaccctg
    33001 caaactctta cgttctttcc caaatggcat atcgtaaagg tcgtatttcc aacggcatga
    33061 ctgagaacat ccaccacggt tggcatcacg catactctag acggattgtt ttgacaattc
    33121 taatctttta gactttgcat aataactgtt aaacagtcga aaattacccc agttttaaca
    33181 agtagtcaaa ataccagata aaggaaaaaa gtctttaaaa tcttaaaaac gcatagtatc
    33241 aggtattgaa caatcttgat attatgcgtt ttattgtggg aagatttact tcattttctc
    33301 ttgaaattga gttttctcct acttcaaaac tagatgattt gctatttaaa atagcgttcc
    33361 ttatgatttt ggcaacctgg attaaagcga gaaaaacaaa aggggcaact taaactttct
    33421 ttatattgct tatatgttag tagttttaga caaacaccac ataaaatagg cttatcctgt
    33481 atcaaagata agggatacgg ctcaaaaggg tgattttcta atgaatcatg acaccgataa
    33541 caagcataat actttttaca atcatagcat tgtaaagcaa taatatccag cttgctatgg
    33601 taatgaatgc atcttgtttg cttatccact aagaaaccct gtgcctctat catttccttt
    33661 tcctttctta agctcgaact gtgacgctgg ttccatcttc cttataaaaa ttgatgagtc
    33721 cttcttttaa tgcacgaacc atgtctccag cttgaacggg ttgtgggact ttaatagtca
    33781 atagttccat tggatttgga gcgcggtcga ttttattgcc tttggcatca tgcaaatctt
    33841 caatataggt ttcaaaatga cggaaacctg gaccataaaa ctcaacttgg tccccttcgt
    33901 taatgacgtt tcgttgacga atggttgctg tttgtgtcgc atcatcataa gaaaccactt
    33961 cagcgacaaa cttgtactca gggattttac ggcgagcacc aaacaactgc tcattttcag
    34021 atggtatacc gtagtagaaa cctgttgcca attcacgttg ggcaaccttc cacatctcgt
    34081 ccactaagtc ttgtttgata gcttcaaact tttcaggact ttcaagatag gcatccacag
    34141 ccgccttgta gcagttggtt actgttgata cgtagtgaat agacttcata cgtccttcga
    34201 tttttagact gtccacacca ttttcaatca tatctggaat gtggtcaatc atagacatgt
    34261 caacggctga cattgaaaat tcttctggaa tctcaccctg caaactctta cgttctttcc
    34321 caaatggcat atcgtaaagg tcgtatttcc aacggcatga ctgagaacat ccaccacggt
    34381 tggcatcacg catactcatg tggtttgaaa gagtacaacg tccagagtat gaaatacaca
    34441 tagctccatg gacaaaggct tcaatttcaa catctgtacg tttgcggatc tcagctaatt
    34501 cttccattga aacctcacgc gctaaaacga cacgagtcaa gcctagctct ttccagaact
    34561 caagggtttc atagttagtg gcactggctt gggtagaaag gtggatttca aggcctggtg
    34621 cttcagtcgc tgcaatcata atcaaggctg ggtcagatac gataactgct gcaatcccga
    34681 tatcacgcag tttacggaac cactcaccag caccagcttc atttccttcg tgcataacca
    34741 tattagccgc tacatagacc ttggcaccat acttggccgc aaactgcacg ccttcttcca
    34801 tctgttcgaa agtaaagttt cccgcacggc tacgaagacc ataggcctga ccaccgataa
    34861 agacagcatc tgctccatac tgaacagcta cctttagctt ctctaaagtc cctgcaggtg
    34921 ataaaacctc aggacgtttt aatgtttttg tcatgatttc tcctatttgc aatataaaag
    34981 tttgacattt ttccttctca ttttatagta aataaaggat aaaatcaagc ctagacggat
    35041 tgttttgaca attctaatct tttagacttt gcataataac tgttaaacag tcgaaaatta
    35101 tcccagtttt aacaagtagt caaaaagtct agaaaagtaa aaaccagtat ccaaagatac
    35161 tgactcgtaa aaatacataa attagtcctt agatgactac tcccactctg ttgctcctat
    35221 aatggaaaag gattgataca gtctagaata tcgctttttt atttattatt ctgatataaa
    35281 actgttagaa ttgatttttt gttttatacc caaatatgaa tagagacgta gctaataagt
    35341 tgaataacat atttggaaaa atgagaaata gcaatattac tagaactttt agaaacaatc
    35401 aatatttaaa aagaaaaagc tcaaagaatt tattaaacca tgttataata gatatagcta
    35461 taattttatt tataacaaga ggatagaaat gaccgaatta gaaagaaaaa atcgaaaaat
    35521 tagctaagaa atattctgat aacttaaaca tcaaagttca agagagagtt cgtgaaatgg
    35581 caaatgataa taagagccat tatttgatat acagagtttt aggtatttca tttgaagaag
    35641 gagaaaatat cgatttgtat caaaataaag gtcgtttttt atacaaatat gctggttcat
    35701 ttttagaaga agctgcagta ctatccttta acgaaaaatt tggtacagaa aatacttaaa
    35761 aagttaacat tcctaattct gaaagtacaa aacctaagac ttttgaaatt gattgtttag
    35821 tcggagaaaa acacgcatac gaaataaaat ggtgggatgc aactacagat ggagaccata
    35881 taactaaaga acacactaga ataaaagtta ttcataacaa aggatatata ccaattcggt
    35941 taatgttcta ctatccaaat agaactcaag ctataaaaat tcagcaaact ttagaaacat
    36001 tgtataacgg tattggaggg aaatattatg gagattctgc ctgggaagat ttaagagcag
    36061 tgaccggtat tgatttactt agtattctaa cagatattgc aaataaaaaa caggggtaaa
    36121 atcaaaatga cagtattaaa aggagataac ttagaaatat taaaaactat tgaatcctca
    36181 agtattgatt taatctatat ggaccctcct ttctttacac agaaaaccca aaaattatct
    36241 aataacaaaa atattatgta ttcattcgaa gatacgtgga cttcgattga ggattacaaa
    36301 gaatttttgt ctgtaagatt agaagaatgc aaaagagtgc taaaaaatag tggcagtatt
    36361 ttcgttcatt gtgataaaat tgcaaatcat catattagat taattttaga taatatcttt
    36421 ggagcagata tgtttcaaag cgaaattata tggaactata aacggtggtc taattcaaaa
    36481 aagggattat tgaacaatca tcaaaacatt tacttttatt caaagtcaaa agattttaaa
    36541 tttaatacaa tttttacaga gtattcttct actacaaata tcgaccaaat actagtggaa
    36601 cgaaaacgag atggaaactc taaaactata tataaagttg ataataatgg taactatatt
    36661 ctagcaaaag agaaaaatgg agttcccctt tcagatgttt ggaatatacc atttcttaat
    36721 ccaaaagcta aagaaagagt aggttatcct acacaaaaac ctattctgtt attagaacaa
    36781 attataaaga ttgctactga taaaaatgat atagttttag acccgttctg tggaagtgga
    36841 actactttag tagcctccaa gattttgaat agaaattata tggggattga tttatctgag
    36901 gaagctatca atataactca gcaacgtctg gaaaatgtta taaaaacaag ttcagattta
    36961 ttgaataaag gaatcgaagc atatagaacc aaaactgagg aagaggaaaa cattcttaaa
    37021 ttattacagg caaaaattgt tcaaagaaat aaaggaattg atggtttttt acctaaacat
    37081 tttcaaaaaa aaccgatacc tataaaaatt caaaaaaata atgaatgtct gaatgagagt
    37141 atctctttat tacagaatgc tataaactcc aaaaaacttg attttggagt agttataaaa
    37201 actcattcag ataatttatt atttgatttt gatacgattc ctgaaaatat aatagtagtt
    37261 gaccattttg aacttacaat cgaaaaatgg ttaagtaaaa gtcaacagtt actatagttt
    37321 gcaaattatt tacagaaaga acaaaaaatg ctctgaaaca ctgatttcaa ggcatttttt
    37381 gttagtttaa aattactccc attcttcttt tccaaacata caatatatcc aaaaccattc
    37441 aaaatactag attctatttt ttataatatc actaaatcca cctaattata ggacgttttc
    37501 agatttttag tcccgtccca gtcccagtac cggagaaata ttgttttaat ataatatctc
    37561 tttttgtctt ctaagctctt aaaagcaaaa gaacaagtaa agagtcaaga caaggataaa
    37621 aagtccatat tagggcaaat aaaaagcttt aagacagatg acaaatctaa gtcaaataag
    37681 aaagaccata gcaaaggtgc agagagataa atattggcgg tcttcggact gcctttattt
    37741 ttttatccat ttttcaaatc aaatttattc agactatata tgcacatata cacttaaatt
    37801 catataaaaa catggcttgt aaaaaattac tttaatcaca ataatcgcat ttaaaattgt
    37861 gatgtttgca agctaaatta cggacttcac ttggaagttt tcccttgtat cttttataat
    37921 agatagaaaa tttgctggca gatgaatatc caacagattc tgctatctct tttataggta
    37981 gttcagtgtt taaaagaaga gtttcagcta cattcattct ttttctttga gtgtactctg
    38041 taatgctttg acaatatttt tccttaaata aattttttaa tttagtacca ctcattttag
    38101 atattttttc aagcgtgcct tgatttacat tcgttgcaaa atgatcatct aagaatcttg
    38161 ctacatcttc aagtgcttta tcatcatcaa tttcaatttt atattttttt ctatttaagt
    38221 atgtgtcaat tactatactt atccattcat ttgcctttgc tttaaagaaa aaatcagcgg
    38281 caggagcgtc catcttacaa tttaatattt ccattgccac tctttctaag gcctttgtaa
    38341 gtattatttg attcgattga agcaaggttg aataaaaaga ttctggatta atgttaatag
    38401 atgctaaatg tttttctatt agctcttttt taaaaccaat ggaaacagca agataacaac
    38461 aattctcgtg taataaaaaa acaaaatcat cttttatatt atcaaaatca aaagtacata
    38521 aagagtttgc ggtaatagtt tgatacggat taaacttttc tccgtttgca ctgacaatgt
    38581 aacttgaata aattgaaaca tagtctgaca tactataagt gctattttga actacttcct
    38641 ctttgatata aaaatcatgt atatcgataa tgaagctgcc tccttcataa aaccaatata
    38701 ggccttctgc ataagttgaa ttctcttttt tccaacaaaa tgtatgacct gcacttgaat
    38761 acttctcatt gtttttacat tcatctactt tcatataatc ttttacaaaa tcataatatg
    38821 acataacaca ctatcccttt tagacaatat tccaattagc cttattaatt caaaactatt
    38881 gtattagtaa ttataacaga tgtataatag aaaagcaatg atagatatta tcaattaagc
    38941 gaatttatat ctaaaaggga tattaaagaa aggagatatg cttatgaaga tttacaaaaa
    39001 actatttgct tatgtccaag ataagaaata tcttggggtt ttggccataa ttttttctgc
    39061 tatatctgct gcacttacag tatatggata ttatttaatc tacaaatttc tagataagtt
    39121 aataattaat tcaaacttat ccggtgcaga gagtatagca ttaaaatctg ttattacact
    39181 aacaagtgga gcgatatttt attttgtctc aggaatgttt tcacatatct tgggatttag
    39241 gcttgaaaca aatttaagaa aaaggggaat cgatggtctg gaaaaagcaa gttttaggtt
    39301 ctttgactta aatccatctg gtcaaataag aaagatcata gatgataatg cagcacaaac
    39361 tcatcaggtg gtagcacaca tgattcccga tagttctcag gcaataatca cacccgtact
    39421 tgtacttgca cttggcttta tagtaagtat aagggttggc ataattttgc ttgctcttac
    39481 tataattggt ggcttaattt taggggcaat gatgggcgag caagaattta tgaagatata
    39541 ccaagaatcc ctatctaaac taagtgctga aactgttgag tacgtgagag gaatgcaagt
    39601 tgtaaaaata tttaaagcaa atgtagagtc ttttaaaagc ttttataagg cgataaaaga
    39661 ttactcaaag tatgcttatg attattccct atcttgtaaa aggccttatg ttttgtatca
    39721 atggttattt tttggactga ttgcaatttt aattattcct atagtttatt ttatgactag
    39781 cttagctagc gcaaaggtga ttttacttga gcttatcatg attttatttt tatcaggagt
    39841 tctctttgtt tcattcatga gaatgatgtg gtactccatg tatatttctc aaggaaatta
    39901 tgcagtagat actttagagg cgctttacga agatatgcaa aaagacaaat tagtgcatgg
    39961 taatgtcaat aattttaaaa actataatat agaatttgag aatgttagct ttgcttataa
    40021 tgataaagct gtcattgaaa atttatcctt taatttagaa gaaggaaagt cctacgcact
    40081 tgtcggttca tctggatcag gcaaatcaac agtagcaaaa cttatatcag gtttttacaa
    40141 tgttaataaa ggaagcataa agataggcgg gatagcaata agtgaatatt ctgacgaagc
    40201 cttaattaaa gccatttcct ttgtttttca agattcaaaa ttattcaaga agagcattta
    40261 tgataatgta gctttagcta ataaagatgc gacgaaagat gacgttatga gagccttaaa
    40321 attagcagga tgcgatttaa tattagacaa attcccagaa agagaaaata caatcatagg
    40381 ctcaaaaggt gtttatttat ccggtggaga aaaacaaaga attgcaattg ctagagcaat
    40441 tttaaaggat tccaaaatta ttattatgga tgaagcatca gcatctattg acccagataa
    40501 cgagtttgaa ttgcaaaaag cttttaaaaa tcttatgaag gataaaacag ttatcatgat
    40561 tgcacacagg ctatctacaa ttaaagacct tgatgaaatt attgtcatgg atagtggaaa
    40621 aattatagaa agagggtctg acaaagaatt aatgtcaaaa gatacaaggt ataagagcct
    40681 gcaagagatg tttaacagtg cgaatgaatg gagggtttca aatgaaagag ttttataaaa
    40741 aaagatttgc tcttacagat ggaggagcaa gaaatttaag taaagcaaca ctggcttcat
    40801 ttttcgttta ttgtataaac atgcttcctg ccatattact tatgattttt gctcaggaag
    40861 ttttggaaaa tatgggcaaa agcaatggct tttatatagt attctcagtt ttgactttga
    40921 tagcaatgta tattttgctt tctatcgaat acgataaatt atataacaca acctatcaag
    40981 aaagtgcaga tttaagaata aggacagcgg agaatttatc aaaattacct ctatcttact
    41041 tttctaaaca tgacatttcc gacatttcac aaacaatcat ggctgatatt gaaggcatag
    41101 agcatgcaat gagccactca ataccaaagg tgggcggcat ggtactgttt ttcccattaa
    41161 tatctgtaat gatgctagcg ggcaatgtca agatgggttt agctgtaatt attccatcta
    41221 ttttaagctt tatatttata cctttatcta aaaaatatca ggttaatgga cagaatagat
    41281 attatgatgt cttaagaaaa aactcagaaa gctttcaaga aaatatcgaa atgcaaatgg
    41341 agattaaagc atataattta tcgaaggata ttaaagatga cttatataaa aaaatggaag
    41401 atagtgagag agtacactta aaggcggaag taactacaat tttaactttg tctatatctt
    41461 caatatttag ctttatatct cttgctgttg tgatatttgt cggcgtaaat ctaattatta
    41521 ataaagagat aaattctctc taccttatag gatatttact agctgctatg aagataaaag
    41581 actctttaga tgcatctaaa gagggcttga tggaaatatt ttatttatcg cccaaaatag
    41641 aaagattaaa agaaattcaa aatcaagatc tacaagaagg cgatgactat agcttaaaaa
    41701 aatttgatat tgatctaaaa gatgttgagt ttgcctacaa taaagacgca aaagttttaa
    41761 atggtgtaag ttttaaagct aagcagggag aggtcactgc tttggtaggt gcaagtggct
    41821 gcggtaaaac aactatcttg aaacttatat caagacttta tgattatgac aagggacaaa
    41881 tcttaatcaa tggcaaagat ataaaagaaa tatcaacaga atctcttttt gataaggtct
    41941 ctatagtttt ccaagatgtg gttctcttta atcaaagcgt tatggaaaat attagaatcg
    42001 gaaagcaaga tgcaagtgac gaagaggtta aaagagcagc aaaacttgca aattgcacag
    42061 attttataga aaaaatggat aaaggtttcg atacagttat tggtgagaac ggagctgagc
    42121 tatcaggagg agaaagacaa agattatcaa tagccagagc cttcttaaaa gatgcgccga
    42181 tattgatctt agatgagata acagcaagcc ttgatgttaa caacgagaaa aagattcaag
    42241 agtctttaaa taatttagtt aaagataaaa ctgttgtaat catttcacat agaatgaaat
    42301 ccatagaaaa tgcagacaag atagtagttc ttcaaaacgg aagagtagaa agcgaaggta
    42361 agcatgaaga gcttttacaa aaatcaaaaa tttacaaaaa tttaatagaa aagacaaaaa
    42421 tggcagaaga atttatttat taggaggact acaatggata ataaaaaatt aaaagtaaaa
    42481 gatttagtaa gcatcggtgt ttttggcgta atttattttg ccttcatgtt tggagttggt
    42541 atgatgggct tgattccaat attgttctta atatacccga cagtattagc catagttgca
    42601 ggaactgttg ttatgttatt tatggctaag gttcaaaagc catgggcact atttatattt
    42661 ggtatgatat caccacttgt gatgtttgca gctggtcata cctacgtagt tgtggtttta
    42721 tcacttatag taatgataat agcagaatta attagaaaga ttggtaatta taattcattt
    42781 aaatacaata tgctttctta tgcaatcttc agcacatgga tatgtagctc tttaatgcaa
    42841 atgcttttag caaaagaaaa atatatggag tggtctttga tgacgatggg aaaagattat
    42901 gttgatgtat tagaaaagtt aataacttat cctcacatgg ctttagtagc cttaggtgct
    42961 ttcttaggag gaattcttgg agcatatata ggcaaggctc tattgaaaaa acactttgaa
    43021 aaagcaggca ttgtataatg cctacttttt cttcaaatgc tccctttaat cccaatccga
    43081 tctctaagat attagtcgta tttatcacag gcttaactgt tatgcatagc ataaacatcc
    43141 gttttgagct ggcaattgtt tgtcttattg gtattttgct ttatttgaat ggatacaaaa
    43201 aaacactttt caaatggatt atattgtgtg ggatacttta ctccttgcct aattttatgg
    43261 tgttatctga attaaaccct atagttaaga tgtttttgag tatacctatt gttattagaa
    43321 tgtttatttt accatttatg gcagcaagct ttatgataaa gacctcggat gtaggcgcaa
    43381 taatttcatc gatggataag cttaagattt caaagaatgt atccatacct attgcggtta
    43441 tgtttagatt cttcccatct tttaaggagg agaagaaaaa catcaaaatg gctatgagag
    43501 taagagggat aaattttaaa aacccagtca aatatcttga atatgtttct gtgccactac
    43561 tcattatatc atctaatata tcagatgaca ttgcaaaagc ggcagaaaca aaggcaatag
    43621 aaaatccaat tgccaagacc agatacattc gcgtaaagat acagctaatt gattttgttt
    43681 atgttttagc ggttgttgga cttattgtgg gaggcttaat atggttgaaa taaaaaattt
    43741 aagtcttgat tatggtgaag agcatatatt agatgatata tcactatcca tagccgaggg
    43801 agagtgcgtg ctatttacag gaaaaagtgg aaatggtaag tcatctttaa taaattcaat
    43861 caatggacta gctgtaaggt atgacaacgc aaagacaaag ggcgaaatca ttattgatgg
    43921 taagaatata aaaaatttgg aactttatca aatctcaatg cttgtttcaa ctgtttttca
    43981 aaatcctaag acatattttt ttaatgtcaa tacgacatta gaattattat tttatttgga
    44041 aaatatcggt cttgcaagag aagagatgga caggcgtttg aaggatatgc ttaagatatt
    44101 cccgataaaa aatcttttga acagaaatat atttaatcta tccggcggtg aaaaacaaat
    44161 tctttgcatt gcagcttctt atatagcagg tacaaagatt atagttatgg atgagccttc
    44221 atcgaattta gatattaaaa gcataagtgt tttggcaaag atgctaaaga tattaaaaga
    44281 gaaaggtata agcataattg ttgcagagca tagaatttat tatttgatgg acatagttga
    44341 ccgtgtattt ttaatagata aaggaaagct taaaaaaact tatactagaa gtgaattttt
    44401 aaagctagat aaaaatgaat taaatgcttt aagtttaaga gataaagaat taagtaaatt
    44461 aaaagttcct tatttaaaag aaggtggaga gtatcagata aaaaatctta gctacaaatt
    44521 tactgatgat gagtgtttaa gcttaaaaga tatttcattc aagcttggga aaatttatgg
    44581 cataatagga tccaacggac gaggaaaatc aacgctttta agatgtttaa taggtcttga
    44641 gaaaaaatca aaagaagaaa tttattttaa gggagagaag ctatctaaaa aagaaagact
    44701 caaaaactct tcacttgtta tgcaagatgt aaatcatcaa ttattcacag atgaagtatt
    44761 caacgagctt agattaggag taaagaattt tgatgaagaa aaggcgaaaa tcattttaaa
    44821 agatttaggc ctggacgaat ttattgaaag gcatccgatg agtttatcag gagggcaaaa
    44881 gcaaaggctt gcaatagcat ctgttatgtg caagacttct ccatttgtct tttttgacga
    44941 accttcaagt ggtatggatt attccaatat gataaaaata tctgaactga ttaataagta
    45001 taaaaccatg gataaaataa tttttattgt ttcccatgat atagaatttt taaatgaagt
    45061 ggcagatgaa atttttgaat tgtaaaatag agtctgttaa acatgtctat agaactagta
    45121 aattgtctaa aaatttaaaa gatactaaca catattgata tttattagaa aattaacttc
    45181 aggattttta cagtatttat aaactttata atatgtattt atagtattaa taatttccat
    45241 atctttaggg aaattcttta tttacttacc ataattaaag agatgagaga taaatatcgg
    45301 cagtcttcgg actgccttta tttttttact taatttaatg cagtaaatca tacgattgaa
    45361 aggaatctgc gttatatgct ataattaggt ggttaatcta tacatttaga aaggtaaaat
    45421 atagaattgg agaatgatat gggattttca tataataaat tgtaaccgtc caataacgaa
    45481 gtatattgaa aaatctccag actagagaac tcacg
//
LOCUS       DAVBNN010000012        43373 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBNN010000012 DAVBNN010000000
VERSION     DAVBNN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.012"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(191..394)
                     /locus_tag="VQ847_000695"
     CDS             complement(191..394)
                     /locus_tag="VQ847_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050075.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(387..1469)
                     /locus_tag="VQ847_000696"
     CDS             complement(387..1469)
                     /locus_tag="VQ847_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3050076.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1595..2377)
                     /locus_tag="VQ847_000697"
     CDS             complement(1595..2377)
                     /locus_tag="VQ847_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3050077.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2377..3720)
                     /locus_tag="VQ847_000698"
     CDS             complement(2377..3720)
                     /locus_tag="VQ847_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3050078.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3819..5135)
                     /locus_tag="VQ847_000699"
     CDS             complement(3819..5135)
                     /locus_tag="VQ847_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3050079.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5329..6555
                     /locus_tag="VQ847_000700"
     CDS             5329..6555
                     /locus_tag="VQ847_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3050080.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6754..8328
                     /locus_tag="VQ847_000701"
     CDS             6754..8328
                     /locus_tag="VQ847_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3050081.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8593..9381
                     /gene="codY"
                     /locus_tag="VQ847_000702"
     CDS             8593..9381
                     /gene="codY"
                     /locus_tag="VQ847_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3050082.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9381..9956
                     /locus_tag="VQ847_000703"
     CDS             9381..9956
                     /locus_tag="VQ847_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3050083.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10038..10123
                     /locus_tag="VQ847_000704"
     tRNA            10038..10123
                     /locus_tag="VQ847_000704"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10072..10074,aa:Leu,seq:aag)
     gene            10406..11536
                     /gene="ugpC"
                     /locus_tag="VQ847_000705"
     CDS             10406..11536
                     /gene="ugpC"
                     /locus_tag="VQ847_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3050084.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12037..12795
                     /locus_tag="VQ847_000706"
     CDS             12037..12795
                     /locus_tag="VQ847_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3050085.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12882..13394
                     /locus_tag="VQ847_000707"
     CDS             12882..13394
                     /locus_tag="VQ847_000707"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3050086.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13576..14520
                     /locus_tag="VQ847_000708"
     CDS             13576..14520
                     /locus_tag="VQ847_000708"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3050087.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14529..15206
                     /locus_tag="VQ847_000709"
     CDS             14529..15206
                     /locus_tag="VQ847_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3050088.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15304..16062
                     /locus_tag="VQ847_000710"
     CDS             15304..16062
                     /locus_tag="VQ847_000710"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3050089.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16100..17605
                     /gene="lytC"
                     /locus_tag="VQ847_000711"
     CDS             16100..17605
                     /gene="lytC"
                     /locus_tag="VQ847_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3050090.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18102..18620
                     /locus_tag="VQ847_000712"
     CDS             18102..18620
                     /locus_tag="VQ847_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3050091.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            18750..19256
                     /locus_tag="VQ847_000713"
     CDS             18750..19256
                     /locus_tag="VQ847_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3050092.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19458..20690
                     /gene="clpX"
                     /locus_tag="VQ847_000714"
     CDS             19458..20690
                     /gene="clpX"
                     /locus_tag="VQ847_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3050093.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20699..21286
                     /locus_tag="VQ847_000715"
     CDS             20699..21286
                     /locus_tag="VQ847_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3050094.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21297..21677
                     /locus_tag="VQ847_000716"
     CDS             21297..21677
                     /locus_tag="VQ847_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3050095.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21729..22619
                     /gene="rapZ"
                     /locus_tag="VQ847_000717"
     CDS             21729..22619
                     /gene="rapZ"
                     /locus_tag="VQ847_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3050096.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22616..23593
                     /locus_tag="VQ847_000718"
     CDS             22616..23593
                     /locus_tag="VQ847_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3050097.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23590..24501
                     /gene="whiA"
                     /locus_tag="VQ847_000719"
     CDS             23590..24501
                     /gene="whiA"
                     /locus_tag="VQ847_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3050098.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24535..25503)
                     /locus_tag="VQ847_000720"
     CDS             complement(24535..25503)
                     /locus_tag="VQ847_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3050099.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25639..26496
                     /locus_tag="VQ847_000721"
     CDS             25639..26496
                     /locus_tag="VQ847_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3050100.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26483..27262
                     /locus_tag="VQ847_000722"
     CDS             26483..27262
                     /locus_tag="VQ847_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3050101.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27286..28638
                     /locus_tag="VQ847_000723"
     CDS             27286..28638
                     /locus_tag="VQ847_000723"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3050102.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            28712..29086
                     /locus_tag="VQ847_000724"
     CDS             28712..29086
                     /locus_tag="VQ847_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3050103.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29088..29936
                     /locus_tag="VQ847_000725"
     CDS             29088..29936
                     /locus_tag="VQ847_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3050104.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30213..30980
                     /locus_tag="VQ847_000726"
     CDS             30213..30980
                     /locus_tag="VQ847_000726"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3050105.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            30992..32176
                     /locus_tag="VQ847_000727"
     CDS             30992..32176
                     /locus_tag="VQ847_000727"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3050106.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32173..34044
                     /locus_tag="VQ847_000728"
     CDS             32173..34044
                     /locus_tag="VQ847_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3050107.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34187..35371)
                     /gene="mntE"
                     /locus_tag="VQ847_000729"
     CDS             complement(34187..35371)
                     /gene="mntE"
                     /locus_tag="VQ847_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3050108.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            35675..38371
                     /locus_tag="VQ847_000730"
     CDS             35675..38371
                     /locus_tag="VQ847_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3050109.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38384..39175
                     /gene="yghU"
                     /locus_tag="VQ847_000731"
     CDS             38384..39175
                     /gene="yghU"
                     /locus_tag="VQ847_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3050110.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39291..39701
                     /locus_tag="VQ847_000732"
     CDS             39291..39701
                     /locus_tag="VQ847_000732"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3050111.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVKKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            39713..41308
                     /locus_tag="VQ847_000733"
     CDS             39713..41308
                     /locus_tag="VQ847_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050112.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            41375..41539
                     /locus_tag="VQ847_000734"
     CDS             41375..41539
                     /locus_tag="VQ847_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3050113.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41618..42346
                     /gene="yaaA"
                     /locus_tag="VQ847_000735"
     CDS             41618..42346
                     /gene="yaaA"
                     /locus_tag="VQ847_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3050114.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42623..43171)
                     /locus_tag="VQ847_000736"
     CDS             complement(42623..43171)
                     /locus_tag="VQ847_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3050115.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
BASE COUNT        12749 a         8106 c         9886 g        12632 t
ORIGIN      
        1 aagaaaatta agttaaaact aaaaggactt agccctgtgc aatacagaac taaatccttc
       61 ggataaatta attgtctaac tttttggggg cagtacacaa tacctgatag tatgcgtttt
      121 attgtgggaa gattttcctc attttctagt gaaattgaac tttttctaac atcttttgat
      181 agatgacttc ttaatcaatt atcatttcca ttgttgtttc ttggggtttc atcccttgtc
      241 tttgataaaa gcggagagca ccctcgttat cattccagac acttagggtt agattattgc
      301 agccaatttc tttagcataa tagcagaaaa atgacaataa aatagcccct agatattttg
      361 aaaggaaagc ataggggcta tatagtttaa tcaaaataaa gcaaatcttt gctggtgctt
      421 gtaaagaggt cgaagccatc cttggtaaca acaccgcagt cttcaatacg aacaccgact
      481 ttaccaggga tatagatacc tggttcaaca gagaagcaca tgccttcttc gatgaccatg
      541 tcgtttcctt ccatgataga tgggaattca tggacatcca taccgatacc atgcccgaga
      601 cggtgattga agtactcacc ataaccagct ttttcgatga cctcacgggc agcgcggtcc
      661 acttcatgag cagtcacacc tggcttgata aagtcaagag cagcttgttg ggcttcaaga
      721 gtcaagttgt aaatatcttt cttgaattgg tctggtttgc cgacagcgac tgtacgagtc
      781 atatctgacg catagccatt gaccagaaca cccaggtcaa agaggagaag agcatcattt
      841 tcaaccttat tagctgctgg aatgccgtgt ggattcgcag cattatcacc agtcaagacc
      901 atggtatcaa agctcatttc ataaccttca cgtttcatgg caaagtcgat ttgtgcgatg
      961 atatctgtct cagtcttatc aagagaaata ttgtcaaaac caacatgaac agccttgtca
     1021 gcataaagac ctgcaaccat cattttttgc acttcatcag ctgatttgat gaggcgcatg
     1081 cgttggatac gaggagtgag gttgtcaaac tcagcagtct caaaaactgt tttcaaacca
     1141 tggtatttgg tcaagatgag attgtcaaac tcaacagcga cacgtttgaa gtcaagttgt
     1201 ggaagagcat gtttgatttt ttgccatgga ttttcagaat cgacatagcc cactactggg
     1261 aaggaaacgg tgctacttgc acgttctact tcaagagctg ggacaaagag gagaggttcc
     1321 tgatccgcta ggacaaagag gaacatttgg cgttcatggg gatcactgta aaaaccagtg
     1381 aggtaattga ttgtgacggg gtcagatacg acagcgacgt ctagtttttc tgattcaaga
     1441 tatgttagga tttgttgtaa tttagacata tgctaccttc tttctacccc tctattttgg
     1501 caaaaaatga gagaaaatgc aagggagaag ggtaaaagaa aagacaaaaa actccgacaa
     1561 gataacggag ttctttgata tcattttcct ttgtttaaga aaagtcagcc ttgcttttga
     1621 cgtcactgta ctcttcagcg atttcttggc tgaggatatc ctcataggca gggagttgga
     1681 tatcctgacc atatttcttc ttgagggcag tagtaactag gcgataagcc agattggcat
     1741 tacgagagag gataggcccg tggaagtagg aaccaaagac attcttataa tgaacccctt
     1801 caccgacctt ttcttcgttg tttccatttc catagacaac ctgtcccagc ggtttttggt
     1861 catcagagag gaaggtacgg ccttggtgat tttcaaatcc atagtaggtt tcatcgaaat
     1921 cttcattgtg aatcttgatg tcaccgataa aacggttatt ggtctggttg agcgtgtagt
     1981 gtcccatgac ccctagccct tcgatacgtt ttcctgaagc ttcaacataa tattgaccca
     2041 atagttggaa accaccgcag atagccagaa ctacaccgtc gttttggatg tagttgtcaa
     2101 tgctctcttt tttagcaggt aggtcgtctg caatgatact ttgttcaaag tcttgaccac
     2161 caccgaaaaa ggcgatgtcg tagtgatttt catcaaagtc atcatggaga gaaacgatgt
     2221 caacggtcac atgggctccc agtttttcag ccacatattt gagcatgagg atgtttccat
     2281 tgtccccgta ggtattcatg agatttccgt agaggtgggc aatgttgagc tgataggggt
     2341 aattgccatc ttttgaggaa agtgaagtat aaaccattag ttcatctcct ttctaacaat
     2401 ctgacgacta gccagcagtt cacgaaattc cagcatggca gtataagttg ccagaatata
     2461 ggcatgcttg cagtcttgat tctcaatggt cttgagaact tgctccagat tactcgtttc
     2521 agtgattttc tcagctggat agccagtcac tcggaggcga cgagcgattt cagaatgacg
     2581 aacaccgcca gcgttgattt caggaatgtc catgtcagtg atttgctcaa agtctgcatc
     2641 ccagatccag ctagtgtcaa ttccatctgc atagttggca ttaaggagga cagataggct
     2701 aaatggataa ggtgctagtt tgatcatttc gatagcttgg gttgcaccga ctggattttt
     2761 aatcaagaca agggtacatt tcttgtcacc gatatgaaag gtttcttggc gtccaaagac
     2821 agcacggctc ttgtcaaatc cctgtttgat gagttgcgaa tcggcaccta ggaaacgggc
     2881 gatggccaca gcagctaggg cgttatagat attatagagc ccgccgattt ggataccgta
     2941 ttcttggccg tctatgacaa agcgagagcg attgttggtc aactcaacca gttttgtcaa
     3001 acgatagtcg agatcaggac gtttacatcc acaaccttca cagatatagg cacccaagtt
     3061 tgcataggta ttatgctcat atttgaggat gccttggcag tcaggacaga gaatcccttc
     3121 ggtattgtag tgagccagtt gggctggtcc tttttccaag tcaaaaccaa aatactctat
     3181 agggtttgga atagttggct tgtagaaaag tggactgtct ccgttaagga gaacagtagc
     3241 agttggaact tttcgaatgg catccaatat catgttatag gtagtataga tttcaccgaa
     3301 acggtccatc tggtcacgga agatattagt aatgacaaaa agactaggct ggatatagtc
     3361 acagatacga gatagactgg cttcgtcaat ttcgaggacg gcaatatttt tcccagtttt
     3421 tgaagatttg gctgttagga aggttgttgc aatccctgta atcatgttgg caccgcttgg
     3481 gttggttaga acttgaccat aaacctcttt taaaatgccg acagtgaggg cagttgtcag
     3541 ggtttttcca tttgttccag tgacaacgac aatctcgtag ttcttagcta ggttttgtaa
     3601 aatatcttta tcaaattgaa gggcgacttt acctgggagc gtacttccac gtccaagacg
     3661 gcttaaaacg aagtgggaag aacgcccagc aagaaggccc aaagtagttt ttaagttcat
     3721 gtttctatta tatcacaaaa gagggaaaag acagatttgg tgtttcgtag aagtaaaaac
     3781 agcccaaaga gggctgtcag ttaagatgag atttcaactt aaatcgcaaa caagtcattc
     3841 aagttctcag ccaaggttgg gtgagtgaag atttgttttg tgaagtaagt gtaaggaatc
     3901 ttgttgtcca tagcaacagt aatgatgttg atgatttctt gagaaccttc tgagaagatg
     3961 cttgcaccaa gaatttcttt tgtttcagta ttaacaacag ctttgaaagc tccgcgaagg
     4021 tctccattta cgtgaccacg aggcatggct gcaacaggga tttctttcac tgcgtatgga
     4081 agtttcaaat cagctgcttg gctttcagtc aaaccaactt gtgaaagtgc aggtgtgatg
     4141 aacatagtat ttggcacatt gagacggtcc tcaagtgtgt agctgccatc tccagcaagg
     4201 tagctgtaaa caacacggaa gtcatcaagt gaaatgtaag taaattgaag accaccgttg
     4261 acatctccaa ctgcaaagac accaggaacg tttgtttgac agtgtttatc tactttaata
     4321 gcgccacgtt cagttagttc aatatctgta ttttcaagtt gaagtggttc tacatttggt
     4381 ttgcgtccag ttgcgtagag aagggcgtcg aaacggtaag tttcgtcttc agttacgaca
     4441 agcacttggt caccgtcgtt tttaatttca gtagtatgga tattttgaag caattcaata
     4501 ccgtcttctt ccaggtattg tttagcaaga gctgcgatgg aaggttctgc acgaggtagg
     4561 aatgtatcca aggcatctag gactgtaacc ttgcttccta gtttattgta aaggccagca
     4621 aattcaagac cgatatttcc gccaccaagg actccaagtt tttcaggcaa tttatccaag
     4681 ctttggatac ctgttgagtc aaagacgttt ttgcttgtag caagtccagg gattggcaag
     4741 acgtttgaaa cagcaccagt gttgatgacg atagtttcag cagtcaattc ttgtttttca
     4801 tcaccagctt ggatttcgat gactttattt gaaaggaagt gagcttcagc atcaaagata
     4861 ttgacgccag taccagcaac agtcgtatag tttttaccgt tgaggcgacc agtgatcgtg
     4921 tttttggtag caatgacttc ttcaaaagac aagtctttct cagcagcaac cagcaaagtt
     4981 ttagttggga tacaaccgat gttgatacaa gttccaccgt acatagcttt gctacgttca
     5041 acgagggcaa cttttttgcc agctgaagcc aatttaccag ctagtgtttt accagcttta
     5101 ccaaatccga taacgattaa atcataagtt aacatttaga attcctccta ttcgaattac
     5161 attctagcac aagaaaaaaa cttttgcaca attctgctac gaaaaagaca gaaaaagatg
     5221 aaaacgcttt ccagacaaaa aactagtaat tttttgacaa gcttgataaa ctaaaatcct
     5281 atctattttt atataataaa gaataaatgt tcgaaaatag gaggttttat gaaatcgaat
     5341 cgttatatta ttgcctttgc tggggtcatt ttacacttaa tgctgggttc gacttatgcc
     5401 tggagtgttt atcgtaaccc tattattgaa aaaacgggat gggatcaggc ttctgttgcc
     5461 ttcgccttta gtctagcaat cttttgtttg ggcttatcgg ctgcatttat ggggcgtttg
     5521 gtagaaaaat ttggtccgaa agtcatggga agtctatctg cttttctata cgcaggtgga
     5581 aatatcttaa caggatttgc aatagaccgt caggagctgt ggttgttgta tctcgcttat
     5641 ggcattttag gtgggcttgg tttgggagca ggctatatta cccctgtgtc gacgattata
     5701 aaatggtttc ctgataaacg tggtctcgca acaggtttag cgattatggg gtttggtttt
     5761 gcttctttat tgactagtcc catagcgcaa cacctcatcg caggggtagg gcttgtagaa
     5821 actttttata ttttaggagc aagttacttt attatcatgc tcctagcttc acaattcatt
     5881 aagcgtccaa atgagcaaga gcttgcaatt ttatcttctt cagggaaaga aaaaacagcc
     5941 tctttgacgc aaggaatggc tgcaaatcag gctctaaaaa gcaatcggtt ttatatgctt
     6001 tggattattt tctttatcaa catagcttgt ggtttaggct taatttcagc ggcatcgcca
     6061 atggcacagg agatggctgg cttgtctaca agtcatgcag cagtaatggt gggtgttttg
     6121 gggattttca atggatttgg tcgcttgctc tgggcgagtt tgtctgacta tatcggtcgc
     6181 cctctaacct ttagtatatt actgcttgtt aatcttttct tttctctctc actttggctc
     6241 tttacagatt ccgttttatt tgtagtcgct atgtctattt tgatgacttg ctatggagct
     6301 ggtttttcat tgatcccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6361 ctgcatggat atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6421 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6481 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6541 aaaccgctta catgattttc tgtagaaatg ggactatctt ttgctctggt cttgtgttat
     6601 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6661 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6721 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6781 gctgatttgc tggcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6841 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6901 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     6961 atccaagcct tagtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7021 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7081 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7141 ctcttggact tgattaaacg caaggccttg aaattacaaa acattgaaac ccttatcctt
     7201 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7261 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7321 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7381 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7441 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7501 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7561 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7621 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7681 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7741 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7801 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7861 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7921 gcagatgaaa ccattcgtgc caattttgag aaatttggta aggatgctcg caaattggct
     7981 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8041 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8101 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8161 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8221 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8281 agcgaaaagc aaacaggctt tgttattcgt aacaaaggtg ataaataaga aaaagcggtt
     8341 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaaagacaaa taaaattatt
     8401 atattatctt ttataatatt atgatacaca aaaataggca acttgtcaat agaaaaggaa
     8461 caatttaatt aaaaatattc tggtttttaa ttaaattgta agtcaatgca agtcaataag
     8521 gaattttcag ataattattg aaaaagagac gtttttatgt tataatgata gcgattaaat
     8581 tcgaggtgaa aaatggcaca tttattagaa aaaactagaa aaattacatc aattttgaaa
     8641 cgctcagagg agcagttgca ggatgagctt ccttacaacg ctattacgcg tcagttagcg
     8701 gatattattc attgcaatgc ctgcattatc aatagtaagg gacgtctgct tggctatttt
     8761 atgcgttata aaacaaatac agatcgcgta gagcaattct tccaaactaa gattttccca
     8821 gatgactacg ttcaaggggc taatatgatt tacgaaacag aagcaaactt acctgttgag
     8881 catgatatga gtattttccc tgttgagagt agagatgatt ttccagatgg cttgacgact
     8941 attgcaccga ttcatgtatc ggggattcgc cttggttctt tgattatttg gcgtaatgat
     9001 aaaaaattcg aagatgagga cttggttctt gttgagattg ccagtaccgt tgttgggatt
     9061 cagcttctta acttccaacg tgaagaagat gagaaaaata ttcgtcgtcg tactgctgtc
     9121 accatggcgg tcaataccct ttcttactcc gaactccgtg ctgtttcagc aattttaggg
     9181 gaattaaatg gaaatgaagg gaagttgact gcgtcagtga ttgcagatcg tatcggaatc
     9241 actcgctctg tgattgtcaa tgctcttcgt aaacttgagt ctgcggggat tattgaaagt
     9301 cgctcacttg gaatgaaggg aacctatctt aaggtcttga tttcagatat ttttgaagaa
     9361 gtgaagaaaa gagattacta atgacaaagg ctttaatttc gattgattat acagaagatt
     9421 ttgttgctga tagtgggaaa ctaacagcag gtgctccagc tcaggcgatt tcggatgcca
     9481 tcagcaaggt aactcgatta gcttttgaac gaggagatta tatcttcttt actattgatg
     9541 ctcatgaaga aaacgattgt ttccatccgg aaagtaagtt atttcctcct cataatctga
     9601 ttgggacgag tggacggaat ttatatggag atttggggaa cttttatcaa gagcatggtt
     9661 cagacagtcg tgtcttttgg atggataaac gccattactc agctttttca gggactgacc
     9721 tagatattcg tttgagagag cgtagagtgt ctaccgttat cttaacaggt gtcttgacgg
     9781 atatctgtgt cctacataca gctatagatg cctataatct aggatatgac atcgagattg
     9841 ttaaaccagc tgttgcttcc atctggcctg aaaatcatca atttgcccta ggtcatttca
     9901 aaaatacact cggagctaag ttagtagatg aaaatctaaa tgaactttct gagtaacctg
     9961 gttggtgaaa atgaaaaaat ttgaaaaaaa gtgttgacaa gcatcccaaa agttgatata
    10021 ctagtaaagt aatcgatgcg gggatggcgg aattggcaga cgcgcaggac taaggatcct
    10081 gtgaccgctt taggtcgtga gggttcaagt ccctctctcc gcataggaaa agagttagct
    10141 aaagctagct cttttgtatt tctctaaaaa attagaatcc agtcaaatgt agtggagaat
    10201 cagcgaaaat atgggaaaac tgatccttgt ttctgctttt gtcatagaag aataataaag
    10261 attatcttct tcaaattctc cgatattctc taaagttttg tgcaagttgc acagaacttt
    10321 tttatttttt tggtcatctt gccatagaaa tataaagcgt tttcatatat aatataatta
    10381 tcaaaagaca aaaggagttc acctcatggt agaattgaat cttaaaaata tttacaaaaa
    10441 atatccaaac agcgaacact attcagttga agatttcaac ttgaacatca aagataaaga
    10501 atttatcgtt ttcgtaggac cttcaggatg tggtaaatca actacactcc gtatgattgc
    10561 tggtcttgaa gacattacag aaggtactgc atctatcgat ggcgtggttg tcaacgacgt
    10621 agctccaaaa gaccgtgata tcgccatggt attccaaaac tacgctcttt acccacacat
    10681 gactgtttat gacaacatgg ctttcggttt gaaattgcgt aaatacagca aagaagacat
    10741 taacaaacgt gttcaagaag cagctgaaat acttggattg aaagaattct tggaacgtaa
    10801 accagctgac ctttcaggtg gtcaacgtca acgtgttgcc atggggcgtg cgattgtccg
    10861 tgatgcgaaa gtattcttga tggacgaacc tttgtcaaac ttggatgcca aacttcgtgt
    10921 atcaatgcgt gctgaaatcg ctaaaattca ccgtcgtatc ggagctacaa ctatctatgt
    10981 aactcacgac caaacagaag cgatgacact tgcagaccgt atcgttatta tgtcagctac
    11041 taagaaccct gctggtacag gtactatcgg acgtgtagaa caaatcggca ctcctcaaga
    11101 agtttacaaa aatccagtta acaaattcgt tgcaggattc atcggaagcc cagctatgaa
    11161 cttcatcaac gtgaaattgg ttggtagcga aattgtttct gacggtttcc gtttgaaagt
    11221 gccagaagga gcattgaaag ttcttcgtga aaaaggctac gaaggaaaag aattgatctt
    11281 tggtatccgt ccagaagacg tgaatgcaga acctgctttc cttgaaacat tcccagactg
    11341 tgttgtaaaa gcgactatct ctgtatcaga actgcttggt tcagaatctc acctttactg
    11401 ccaagttggt aaagacgagt ttgttgcaaa agttgatgct cgtgactact tgcaaacagg
    11461 tgcaacagtt gagcttggat ttgacttgaa caaagcacac ttcttcgatg tagaaactga
    11521 aaaaacaatc tactaaaata aataaaattc aaagcactac aagaaaagat atttctttat
    11581 caattgtagt ggagagatat cagttaatct agggagagaa acaaaatgct tctctccttt
    11641 ttgctaggga agtcatatta tgcatctata ttgtgatgct ctttaatact cttcgaaaat
    11701 ctcttcaaac cacgtcaacg tcgccttgcc gtacgtatga ttactgactt cgtcagtttt
    11761 atctgcaacc tcaaagctgt actttgagca gtttacggct agtttcctag tttgctcttt
    11821 gatttccatt gagtattatt tgtgggtacc atctacaagt gaagctatat gcgtaaacta
    11881 cgtgagcaat tgaattcgaa ctagagaggt aataataaat ttatgctata gttatggtga
    11941 cttgtatgct tttgattcta gtttatcaaa taatagatta gaattgtcag ataatatcat
    12001 tttgtgttat aatgaagaaa aaacagaggt gttcaaatgt cagaagcagg tcataagttt
    12061 ttagcaaaat tggggaaaaa acgcttacgt ccaggtggaa agcgtgccac agattggtta
    12121 attgcagaag gaggattttc aaaagaaaag agaatactag aggttgcgtg taatagggga
    12181 actacagcaa ttgagttggc acagcgtttt ggttgcaaga taactgctgt tgatatggat
    12241 gctcaagctt tagaagtggc taaaaaatct gctggaacgg caggtgttgc tcatttaatc
    12301 agttttgaaa gagcaaatgc aatgaaactt ccttatcaag atgctagttt tgatattgtt
    12361 ataaatgaag ctatgctgac tatgcaagcc gatcaagcta agaaaaaatg tgtaatggaa
    12421 tatctaaggg tattaaaacc tggaggtctt ctcttgacac atgatgtact tcttaaggaa
    12481 gctaaagagt ctatcagaca ggaattatca caagcaattc atgtaaatgt aggtccttta
    12541 actcaagatg gttgggaaca ggtgatgata gaatcaggtt attgtgatgt gaaagcattg
    12601 actggtgaaa tgacattaat gaaattatcg ggtatgattt atgacgaagg tttgctagga
    12661 actttgaaaa tttgtgtaaa tgcttgtaaa aaggagaata gaaagcagtt tttaactatg
    12721 tataaaatgt ttgctaagaa taaacagaaa ttgggcttta ttgcgatggc tagttataaa
    12781 tcgtcaaaac gttagataat tattgaagtt aacttttcct tttttctttc ttaaaaaata
    12841 tgctataata gagagtaaaa aactttgaaa gaaagaaaaa gatgaattta aaagattaca
    12901 ttgcaacaat tgaaaattat ccaaaggaag gcattacctt ccgtgatatt agtcctttga
    12961 tggctgatgg aaatgcttat agctacgctg ttcgtgaaat cgttcagtat gctactgaca
    13021 agaaagtcga catgatcgtg ggacctgaag ctcgtggatt tatcgtgggt tgtccagttg
    13081 cctttgagtt gggaattggt tttgcgcctg ttcgtaagcc aggtaaattg ccacgcgaag
    13141 ttatttctgc tgactatgaa aaagagtacg gtgtcgatac cttgactatg cacgcggatg
    13201 ccattaagcc aggtcaacgt gttcttattg tagatgacct tttggcgaca ggtggaactg
    13261 ttaaggcaac tatcgagatg attgaaaaac ttggtggtgt tatggcaggt tgtgccttcc
    13321 ttgttgaatt ggatgaattg aacggccgtg aaaaaattgg tgactacgac tacaaagttc
    13381 ttatgcatta ttaatgaaaa cagtccctag ggctgttttc tctacactag gatataaaaa
    13441 tagactataa ctagttagag aaaaactata attgaaaact atatcttctt acagtataat
    13501 aaaaggacta agtgtttgag atttgtcttc aaacatatgc aattattcct gaaagagtac
    13561 agttaggaga gggttatgcc gattcgaatt gataaaaaat tgccagctgt tgagatttta
    13621 cggacagaga atatctttgt catggatgat caacgtgctg cccaccaaga tatccgtcct
    13681 ttgaagattt taattttaaa tctcatgcca cagaaaatgg tcacagagac ccagttgttg
    13741 cgccacttgg ctaatacacc cctacaactg gatattgatt ttctctatat ggagagccac
    13801 cgttctaaaa caactcgttc agagcacatg gagaccttct ataaaacttt tcctgaagtc
    13861 aaggatgagt attttgatgg gatgatcatc acgggtgctc cagttgagca tttaccattt
    13921 gaggaagtgg actattggga ggaatttaga cagatgcttg agtggtctaa gactcatgtc
    13981 tattcgaccc ttcatatctg ttggggggct caggctgggc tttatctgcg ctatggtgta
    14041 gaaaaatacc agatggacag taagctatca ggtatttatc ctcaggacac cctaaaagag
    14101 ggtcaccttc tatttagagg ctttgatgat agctatgtat cccctcattc acggcacacg
    14161 gagatttcta aggaagaggt cttaaacaag accaatctcg agattttatc agaaggacct
    14221 caggttgggg tttctatttt ggccagtcgt gatttacgag aaatttatag ttttggtcat
    14281 ttggagtatg accgtgatac cttggcaaaa gagtattttc gagatcgtga tgcaggtttc
    14341 gacccacata ttccagaaaa ttactttaaa gatgatgatg ttaatcaggt accttgtctt
    14401 tgttggtctt catctgcagc cctctttttc agtaattggg taaaccatgc ggtctatcag
    14461 gagacgcctt ttgattggag aaagatagaa gatgatgcat ctgcatatgg gtatttataa
    14521 gaggaattat gacatattta gacgctttta aatcaggtat cttggtttta ccgagtgccc
    14581 tgctcttgca ttttaaggaa ctctttcctt ctagcgacga ttttctggtt tggcaatttt
    14641 tctatttgca aaatacgaca ggcttagaag aaatgtcgcc aagccagatt gctgaaagga
    14701 ttggcaagga aatttcggat gtcaaccagt ccatttctaa tctgacggaa aggggactgc
    14761 tccagtatcg tactatcgaa ttaaatggcg aaattgaatt gctctttgat gctagtttgg
    14821 ccttggaacg tttggatgac ctgtttggag cagttcattc aagttcagac cagctgacac
    14881 ctcaaaacca gctcaaggat ttggtggaaa ccttccagca ggagttggga cgattgttga
    14941 cgccttttga gattgaggat ttgaccaaga cactaaagga agatggaacc agtgctgact
    15001 tgattaagga ggctcttcgt gaagctgttt tgaatggaaa accaaactgg aagtacattc
    15061 aggcgatttt gagaaactgg cgccatgaag gaatcaagag tgtggctcaa attgaggcca
    15121 agagagcaga aagagaagca agcaatcctc agttgacaca ggtatctgca gatttcataa
    15181 atgccatgga tctctggaag gattaatcca tgcaagtagg cttgaaatcc gagtaagatt
    15241 tgcaagctgt gtataattgt gatagaataa atagaaaata aattgaaaaa agaggtatgt
    15301 gaaatgtcac gtaaaccatt tatcgctggt aactggaaaa tgaacaaaaa tccagaagaa
    15361 gctaaagcat tcgttgaagc agttgcatca aaacttcctt catcagatct ggttgaagca
    15421 ggtatcgctg ctccagctct tgatttgaca actgttcttg ctgttgcaaa aggctcaaac
    15481 cttaaagttg ctgctcaaaa ctgctatttt gaaaatgcag gtgctttcac tggtgaaact
    15541 agcccacaag ttttgaaaga aatcggtact gactacgttg ttatcggtca ctcagaacgc
    15601 cgtgactact tccatgaaac tgacgaagat atcaacaaaa aagcaaaagc aatctttgcg
    15661 aacggtatgc ttccaatcat ctgttgtggt gaatcacttg aaacttacga agctggtaaa
    15721 gctgctgaat tcgtaggtgc tcaagtatct gctgcattgg ctggattgac tgctgaacaa
    15781 gttgctgcct cagttatcgc ttatgagcca atctgggcta tcggtactgg taaatcagct
    15841 tcacaagacg atgcacaaaa aatgtgtaaa gttgttcgtg acgttgtagc tgctgacttt
    15901 ggtcaagaag tcgcagacaa agttcgtgtt caatacggtg gttctgttaa acctgaaaat
    15961 gttgcttcat acatggcttg cccagacgtt gacggtgccc ttgtaggtgg tgcgtcactt
    16021 gaagctgaaa gcttcttggc tttgcttgac tttgtaaaat aatcagtaag tagcaaaagc
    16081 taggtggaac agcattcaga tgtctgttac attttttata ggagaggaaa gattgaaaac
    16141 aaaaattgga ttagcaagta tctgtttact aggcttggca actagtcatg tcgctgcaaa
    16201 tgaaactgaa gtagcaaaaa cttcgcagga tacaacgaca gcttcaagta gttcagagca
    16261 aaatcagtct tctaataaaa cgcaaacgag cacagaagta cagactaatg ctgctgccca
    16321 ctgggatggg gattattatg taaaggatga tggctctaaa gctcaaagtg aatggatttt
    16381 tgacaactac tataaggcct ggttttatat taattcagat ggtcgttact cgcagaatga
    16441 atggcatgga aattactacc tgaaatcagg tggatatatg gcccaaaacg agtggatcta
    16501 tgacagtaat tacaagagtt ggttttatct caagtcagat ggggcttatg ctcatcaaga
    16561 atggcaattg attggaaata agtggtacta cttcaagaag tggggttaca tggctaaaag
    16621 ccaatggcaa ggaagttatt tcttgaatgg tcaaggagct atgatgcaaa atgaatggct
    16681 ctatgatcca gcctattctg cttattttta tctaaaatcc gatggaactt atgctaacca
    16741 agagtggcaa aaagtgggcg gcaaatggta ctatttcaag aagtggggct atatggctcg
    16801 gaatgagtgg caaggcaact actatttgac tggaagtggt gctatggcga ctgacgaagt
    16861 gattatggat ggtgctcgct atatctttgc ggcctctggt gagctcaaag aaaagaaaga
    16921 tttgaatgtc ggctgggttc acagagatgg taaacgctat ttctttaata atagagaaga
    16981 acaagtggga accgaacatg ctaagaaagt cattgatatt agtgagcaca atggtcgtat
    17041 caatgattgg aaaaaggtta ttgatgagaa cgaggtggat ggtgtcattg ttcgtctagg
    17101 ttatagcggt aaagaagaca aggaattggc gcataacatt aaggagttaa accgtctggg
    17161 aattccttat ggtgtctatc tctataccta tgctgaaaat gagaccgatg ctgagaatga
    17221 cgctaaacag accattgaac ttataaagaa atacaatatg aacctgtctt accctatcta
    17281 ttatgatgtt gagaactggg aatatgtaaa taagagcaag agagctccaa gtgatacaga
    17341 cacttgggtt aaaatcatca acaagtacat ggacacgatg aagcaggcgg gttatcaaaa
    17401 tgtgtatgtc tatagctatc gtagtttatt acagacgcgt ttaaaacacc cagatatttt
    17461 aaaacatgta aactgggtag cggcctatac gaatgcttta gaatgggaaa acccttatta
    17521 ttcaggagaa aaaggttggc aatatacctc ttctgaatac atgaaaggaa tccaagggcg
    17581 cgtagatgtc agcgtttggt attaagcgat gatttgaaag agggatgtga tagtagcacc
    17641 ctctttttct ttgttttatg atagttcatc ctcgagtaaa ttcaagatct tgctcggaaa
    17701 tgaagcttat atagtagatt gaatatagac aaagaccttg tgattggtaa aacattttag
    17761 aaattcattt acctttccta atcgacttgg tttcatctta tttcaatcta ttatagtatt
    17821 ggggaatttc ttcaaaccac atcagcttgg tcagttctac ctgcgacctc aaaacttgtg
    17881 ctttggtcaa gctgggttta gtttcctagt ttgctgatgg atttccattg actataagca
    17941 tccaaccctc ttttttgtct tctaaagaat tcttaaatta tcagtctatt gcaacttttc
    18001 tcatataagt tctttgtctt gctattagtt ttccttagta gtatactaag gtagtaatca
    18061 ttaagaagtg gttacaaaaa ataatgaatg aggtaaagaa aatggtagaa ttgaaaaaag
    18121 aagcagtaaa agacgtaaca tcattgacaa aagcagcgcc agtagcattg gcaaaaacaa
    18181 aggaagtctt gaaccaagct gttgctgatt tgtatgtagc tcacgttgct ttgcaccaag
    18241 tgcactggta tatgcatggt cgtggtttcc ttgtatggca tccaaaaatg gatgagtaca
    18301 tggaagctct tgacggtcaa ttggatgaaa tcagcgaacg cttgattaca ctcggtggaa
    18361 gcccattctc tacattgaca gagttccttc aaaatagtga aatcgaagaa gaagctagtg
    18421 aataccgtaa tgttgaagaa agcttggaac gtgttcttgt tatctaccgt tacttgtcag
    18481 aacttttcca aaaaggtttg gatgtcactg atgaagaagg tgacgatgtg acaaacggta
    18541 tctttgcagg cgctaaaact gaaacagata aaacaatttg gatgcttgca gccgaacttg
    18601 gacaagcacc tggtttgtaa gaaataagga aacatagata aatctgtagg aaatttctta
    18661 cagatttttt ctattttgta agctattcca aaccagtctt tttttgagtt ttttgataaa
    18721 atagtactat cagtgaaaag gatggaagta tgactaagaa aatcgtagct atttgggccc
    18781 aggatgaaga gggtgtgatt ggtaaggaaa atcgtctgcc ttggcatttg ccagcagaat
    18841 tgcagcactt taaagaaaca actctgaatc atgctatctt gatggggcgt gtgacctttg
    18901 atgggatggg gcgtcgcttg cttccaaaac gggaaacctt gattttgacg cgtaatccgg
    18961 aagaaaagat agatggggtt gctacttttc aggacgtcca gtctgttctt gactggtatc
    19021 aggctcaaga aaagaatctc tacattattg gtgggaagca aatttttcag gcttttgaac
    19081 cttaccttga tgaagtgatt gtcactcaca ttcatgctcg tgtggaagga gatacctatt
    19141 tccctgaaga acttgacttg tctctttttg agacagtttc aagcaaattt tacgccaaag
    19201 atgagaagaa tccttatgat tttaccatcc aataccgcaa gagaaaggaa ctctaatgga
    19261 acggagttta tttggtctat tcacggcttt tctgtgtttc atctgctttc tggcaggagc
    19321 acaagctttt cgtaaaaagc gttacgggct ttctatcctc ctttggttaa atgcctttac
    19381 caatctggtc aatagtattc atgcttttta catgacctta ttttagatag aatgacagta
    19441 tagaatggaa ggaaatcatg tctacaaata gaaaaaatga tatgatggtt tattgctcat
    19501 tttgtggcaa aaaccaagaa gaagtacaaa aaataattgc tggcaacaat gcttttattt
    19561 gtaatgaatg cgtggagtta gctcaggaaa tcattcgaga agaattggtt gaggaagtct
    19621 tggcagactt gtctgaggtg ccaaaaccaa ttgaactcct ccatatcttg aaccactatg
    19681 taattggtca agatcgtgcc aagcgtgcct tggcagtggc ggtttataac cactacaaac
    19741 gcatcaattt ccacgataca cgcgaagagt cagaagatgt agatttgcag aagtcaaaca
    19801 ttttgatgat tggcccaact ggttcaggga aaactttcct tgcccagacc ttggctaaga
    19861 gcttgaatgt gccttttgct attgcggatg cgacagctct gacggaggct ggttatgtgg
    19921 gtgaggatgt ggaaaatatc ctcctcaaac tcttgcaggt tgctgacttt aacatcgaac
    19981 gtgcagagcg tggcattatc tatgtggatg aaattgacaa gattgccaag aagagtgaga
    20041 atgtgtctat cacacgtgat gtttctggtg aaggggtgca acaagccctt ctcaagatta
    20101 tcgagggaac tgttgctagc gtgccgcctc aaggtggacg caaacatcca caacaagaga
    20161 tgattcaagt ggatacaaaa aatatcctct tcatcgtggg tggtgctttt gatggtattg
    20221 aagaaattgt caaacaacgt ctgggtgaaa aagtcatcgg atttggtcaa aacaataagg
    20281 cgattgatga aaacagctca tatatgcaag aaatcatcgc tgaagacatt caaaaatttg
    20341 gtattatccc tgagttgatt ggacgcttgc ctgtttttgc ggctcttgag caattgaccg
    20401 ttgatgactt ggttcgcatc ttgaaagagc caagaaatgc cttggtgaaa caataccaaa
    20461 ccttgctttc ttatgatgat gttgagttgg aatttgacga cgaagccctt caagagattg
    20521 ctaataaagc aatcgaacgg aagacagggg cgcgtggact tcgctccatc atcgaagaaa
    20581 ccatgctaga tgttatgttt gaggtgccga gtcaggaaaa tgtgaaattg gttcgcatca
    20641 ctaaagaaac tgtcgatgga acggataaac cgatcctaga aacagcctag aggtgactat
    20701 ggaacttaat atacacaatg ctgaaatctt gctcagtgca gctaataagt cccactatcc
    20761 gcaggatgaa ctgccagaga ttgccctagc agggcgttca aatgttggta aatccagctt
    20821 tatcaacact atgttgaacc gtaagaatct cgcccgtaca tcaggaaaac ctggtaaaac
    20881 ccagctcctg aactttttta acattgatga caagatgcgc tttgtggatg tgcctggtta
    20941 tggctatgct cgtgtttcta aaaaggaacg tgaaaagtgg gggtgcatga ttgaggagta
    21001 cttaacgact cgggaaaatc tccgtgcggt tgtcagtcta gttgaccttc gtcatgaccc
    21061 gtcagcagat gatgtgcaga tgtacgaatt tctcaagtat tatgagattc cagtcatcat
    21121 tgtggcgacc aaggcggaca agattcctcg tggtaaatgg aacaagcatg aatcagcaat
    21181 caaaaagaaa ttaaactttg acccaagtga cgatttcatc ctcttttcat ctgtcagcaa
    21241 ggcagggatg gatgaggctt gggatgcaat cttagaaaaa ttgtgaggaa aagaaaatgg
    21301 caaaaacaat tcatacagat aaggccccaa aggctatcgg accctatgtt caaggaaaaa
    21361 tcgttggcaa ccttttgttt gctagcggtc aagttcccct atcccctgaa actggggaaa
    21421 ttgtaggaga gaatatccaa gaacagacag agcaagtctt gaaaaacatc ggtgctattt
    21481 tggcagaagc aggaacagac tttgaccatg ttgtcaaaac aacttgcttc ttgagcgata
    21541 tgaacgactt tgttcctttt aatgaggttt accaaacggc cttcaaagag gaattcccag
    21601 ctcgttcagc tgtggaggta gctcgtcttc ctcgtgatgt aaaagtcgaa attgaagtca
    21661 tcgcagagat tggataagct agttgaagtt tggtgttgcc aaacttcttt tgatataagg
    21721 agaaaaagat gacaaagaaa caacttcact tggtgattgt gacagggatg agtggcgcag
    21781 ggaaaactgt agccattcag tccttcgagg atctaggtta tttcaccatt gataatatgc
    21841 cgccagctct cttgcctaag tttttgcagc tggttgaaat taaggaagac aatcctaagt
    21901 tggccttggt agtggatatg cgtagccgtt ctttcttttc agagattcaa gctgttttgg
    21961 atgagttgga aaatcaagat ggtttggatt tcaaaatcct ctttttggat gcggctgata
    22021 aggaattggt cgctcgttac aaggaaacca gacggagtca cccactagca gcagacggtc
    22081 gtattttaga tggaatcaag ttggaacgtg aactcttggc acctttgaaa aatatgagcc
    22141 aaaatgtggt ggatacgact gaactcactc cacgtgagct gcgcaaaacc cttgcagagc
    22201 agttttcaga ccaagaacaa gcccagtctt tccgtatcga agtcatgtct ttcggattta
    22261 agtatggaat cccgattgat gcggacttgg tctttgatgt ccgtttcttg ccaaatccct
    22321 attatctacc agaactgaga aaccaaacgg gtgtggatga acctgtttat gattatgtca
    22381 tgaaccatcc tgagtcagaa gacttttatc aacatttatt ggccttgatt gagccgattc
    22441 tgccaagtta ccaaaaggaa ggtaagtccg ttttgaccat tgccatggga tgtacgggtg
    22501 gacaacaccg tagtgtggca tttgctaaac gcttggcgca ggacttatcc aagaattggt
    22561 ctgttaatga agggcatcgc gacaaagacc gcagaaagga aacggtaaac cgttcatgag
    22621 aaaaccaaag ataacggtga ttggtggagg gactggaatt cccgtcattc taaaaagtct
    22681 gcgggaaaaa gatgtggaaa tcgcagctat cgtgacggtg gcagatgatg gtggttcttc
    22741 aggtgaactc cgaaaaaata tgcaacagtt gacaccgcca ggtgatcttc gtaatgtcct
    22801 tgtggccatg tcggatatgc ctaagtttta tgagaaggtc tttcagtatc ggttctctga
    22861 ggatgccgga gcctttgctg gccatccatt gggaaatctc atcattgctg gcttgtcaga
    22921 aatgcagggt tcaacctata atgccatgca gttattgagc aaatttttcc atacaacagg
    22981 gaaaatttat ccttccagtg accatccttt gacccttcat gcagtctttc aggatgggac
    23041 agaagtggtt ggagagagtc atattgtaga ccatcgaggc ataattgaca atgtctatgt
    23101 gactaatgct ctaaacgatg atacgcctct ggccagccgt cgagtagtgc agaccatcct
    23161 tgaaagtgac atgattgtcc tagggccagg ttccctcttt acctctattt tgcccaatat
    23221 cgtgattaag gaaattgggc gggctctttt ggaaaccaag gcagaaattg cctatgtctg
    23281 caatattatg acccaacgtg gagagacgga acactttaca gatagcgacc acgtggaagt
    23341 cttgcatcgt caccttggtc gcccttttat cgacactgtc ttggtgaata ttgaaaaagt
    23401 gcctcagaaa tacatgaatt ccaaccgttt tgatgaatac ttggtgcaag tggaacacga
    23461 ttttgtaggt ctttgtaagc aagtttcgcg cgtgatttca tctaacttcc ttcgtctgga
    23521 aaatggcggt gccttccacg atggagattt gattgtggac gagttgatgc gcattataca
    23581 ggtgaaaaaa tgagtttcac agtagcagta aaagaagaaa tcctgggcca acaccatctg
    23641 agccggcatg aattatctgc cattatcaaa atgtctggta gcatcggtct ctcgacttcg
    23701 ggcttgactt tgtcagttgt gacagaaaat gccaaactgg cccgtcacct ctatgagtcc
    23761 tttctccatt tctatgaaat caaatctgaa attcgtcacc accaacggag caatcttcgc
    23821 aagaatcgcg tctataccgt ttttacagat gaaaaggtgc aggatttgtt aagtgatttg
    23881 cacttggcag actctttctt tggcttggaa acaggtattg atgaggcgat tttatcggat
    23941 gaggaagcag gtcgtgccta tctctgtggc gctttcttgg caaatgggag cattcgtgac
    24001 cctgagtcag gcaagtacca gttggaaatc agttctgttt atctggacca cgcgcaagga
    24061 attgcctccc ttctccaaca gtttttactg gatgccaagg tgcttgagcg caagaagggg
    24121 gctgtgacct atctccagcg agcagaagac attatggact tcttgatagt aatcggagcc
    24181 atgcaggcac gtgatgattt tgagcgggtt aagattttgc gagaaactcg taacgacctc
    24241 aatcgggcta ataatgccga gacagctaat atcgctcgga cagtttctgc cagcatgaag
    24301 accattaaca atatcagtaa aatcaaagat atcatgggct tagaaaattt gccagtagat
    24361 ttgcaggaag tggcgcaact gaggattcag cacccagact actctatcca gcagttagca
    24421 gatagcctca gcacccctct gaccaaaagt ggtgtcaatc acagactcag aaaaatcaat
    24481 aagatagccg atgaattata aaaccacgaa tcctatgtga ctcgtggttc ttttttataa
    24541 actagtagag tgttttggtt gtactttttg ttcagggtca atgtagttga tagcgttgtt
    24601 gacagcagtt ggagcttctc cgaggcctgt cgcaatcaga tcaatttttc cgtcatagta
    24661 gcagcagtca ccgatagcat agatacctgc ttggctggat tcctgtttgc tgttgacgat
    24721 aatcttgtga cggttgaggt cgagccccca gtttttaagg ttaccgacag aagatttgaa
    24781 accatagttg acaaagaggt ggtctaggtc aatggtttca gtttcatcag atttgacttt
    24841 tgtgatttca agtttatcaa gtgtttttcc atttccaagg agttggctag gggcgaatgg
    24901 tgtcttgatg gttacagatg attcttgcaa ggcttgaaca ctgtgttcca aggcacggaa
    24961 attatctctg cggtgaacaa gggtagttgg tgcgattttt tcaaaagcca aagcccaatc
    25021 cacagccgag tctcccccac caagaatcgt cactttctta ccagcgtatt gctgaatgtt
    25081 agaaacgtgg tagtggatat tttcatagcc ctcaacccct tcaagttcca gcggacgtgg
    25141 tttgaaggca ccgccaccca tagcgatgat gactgtttta gtcaagtgac ttcctttaga
    25201 agttgtgatg gcaaattctt cttcttgttt gtcaatctca agaaccgttt cattgagatg
    25261 aataggggta tcaaatccat ttagctgttc aatcaagcgg ttagtcaact cttctccagt
    25321 caggtttggg aagcctggta cgtctaggat ttccttttca gggtagagaa tagcaggttg
    25381 tccacctagc tggggaagag agtcgatgat ttgaaccttg gcttggcgta ggtgggcata
    25441 aaaggctgca aaaagcccga caggaccacc acccacaatg gtaatatcat agagttgaga
    25501 catagtttct cctttgtttt ttctagtcag tttattttat catatttttg ttcaatgtaa
    25561 actggactag gatagggaaa aaaatgccag aaaatggtat aataggacga aagtgttttg
    25621 atagggagga tatcagggat gaattttcaa caattatcca atctgcaata ttggaccagt
    25681 ttgtttgcaa gtccatggac gatagctatc aatctgattg atattttgat tgttgcttat
    25741 attttatacc attttacaaa agctattgca ggaaccaaga ttatgatttt ggtacgtgga
    25801 gttttggtgt ttattttagc tcaaatcctt gcaaatatga ttggtttgac tacgatttct
    25861 tggttaatca atcaaattat tacttatggg gttattgcgg cggttgttat cttctctcca
    25921 gagattcgga ctggtttgga acgtttggga agagcgacag atttcttttc caatgcccct
    25981 attagtgctg aggaacagat gattcgtgcc tttgttaagt ctgttgaata catgagtcct
    26041 cgtaaaatcg gggccttggt tgctattcag cgtgtacgta ccttgcagga gtatatttcg
    26101 acaggaattc ccttggatgc taagatttct gcagaacttc tcattaacat ttttattccc
    26161 aacactcccc tacatgatgg tgcggtgatt atcaaagaag aacgtatcgc tgtgacgtct
    26221 gcctatctgc ccttgacaaa aaacacaggg atttccaagg aatttgggac cagacaccgg
    26281 gcggctatcg gtttatcaga agtctcagat gccttgactt ttgttgtatc agaggaaacg
    26341 ggaggaattt cgataaccta taatggaagg tttaagcaca acctaacact tgatgaattt
    26401 gaaacagaat tacgtgaaat cttacttcca aaagaggaag tgggtcttag ttttaaagaa
    26461 cgattgctag gaggatggaa acatgaaaaa aaatagttta tatatcatat cctcactctt
    26521 ttttgcttgt gtcttatttg tctatgctac ggcgacgaat tttcaaaaca gtaccagtgc
    26581 taggcaggta aaaacggaaa cctatactaa tacagtaaca aatgtcccta ttgacatacg
    26641 ctataatagt gataagtatt ttattagcgg ttttgcttca gaagtatcag tggtcttgac
    26701 tggtgcaaat cgcctatcgc tagctagtga aatgcaagaa agtacacgta aattcaaggt
    26761 tactgctgac ctaacagatg ccggtgttgg aacgattgaa gttcctttga gcattgaaga
    26821 tttacccaat gggctgaccg ctgtggcgac tccgcaaaaa attacagtca agattggtaa
    26881 gaaggctcag aaggataagg taaagattgt accagagatt gaccctagtc aaattgatag
    26941 tcgggtacaa attgaaaatg tcatggtgtc agataaagaa gtgtctatta cgagtgacca
    27001 agagacattg gatagaattg ataagattat cgctgtcttg ccaactagcg aacgcataac
    27061 aggtaattac agtggttcag tacctttgca ggcaatcgac cgcaatggtg ttgtcttacc
    27121 ggcagttatc actccgtttg atacaataat gaaggtgact acaaaaccag tagcaccaag
    27181 ttcaagcaca tcaaattcaa gtacaagcag ttcatcggag acatcttcgt caacgaaagc
    27241 aactagttca aaaacgaatt aaaaatagaa aaggatttta taacaatggg taaatatttt
    27301 gggactgatg gagtccgtgg agaagctaac ctagaactaa caccagaatt agcctttaaa
    27361 ctaggacgtt ttggaggcta tgttcttagt caacatgaaa cggaagcgcc gaaagtcttt
    27421 gtaggacgtg acacacgtat ttcaggggaa atgctggaat cggccttggt ggcaggtctc
    27481 ctttcagtag ggattcacgt atacaaactt ggtgtccttg caacaccagc agtagcttac
    27541 ttggttgaaa ctgaaggagc aagtgccggt gtcatgattt ctgctagcca caacccagcc
    27601 cttgataacg gaatcaagtt ctttggcggt gatggcttca aactagatga tgaaaaagaa
    27661 gcagaaattg aagccttgct agatgctgag gaagacactc ttcctcgtcc aagtgcagaa
    27721 ggcttaggaa tcttggtaga ttatccagaa ggcttgcgta agtatgaagg ataccttgtt
    27781 tcaactggaa ctcctcttga tggaatgaag gttgccttgg atacagctaa tggagcagct
    27841 tctaccagtg cccgtcaaat ctttgcagac cttggtgccc aattgacggt tatcggggaa
    27901 acaccagacg gtcttaacat caaccttaat gttggttcaa cacatccaga agcccttcaa
    27961 gaagtggtca aagaaagtgg gtcagctatt ggtttggcct ttgatggaga cagtgaccgc
    28021 ttgattgctg ttgatgagaa tggtgacatc gtcgatggtg acaagattat gtacatcatc
    28081 ggaaaatacc tttctgaaaa aggacaattg gctcaaaata caattgtgac aactgttatg
    28141 tctaaccttg gtttccacaa ggccttgaat cgcgaaggta ttaacaaggc agttactgca
    28201 gttggtgacc gctacgttgt tgaagaaatg agaaaatcag gctacaacct tggtggtgaa
    28261 cagtctggtc acgttatctt gatggattac aataccacag gtgatggtca attatcagca
    28321 gttcaattga ctaaaatcat gaaggaaact ggtaagagct tatcagagtt ggcggcagaa
    28381 gtaacgattt atccacaaaa attagttaat atccgagtgg aaaacgtcat gaaggaaaag
    28441 gccatggaag tgccagctat caaggccatc atcgagaaga tggaagaaga aatggcgggg
    28501 aacggccgta tccttgttcg tccaagtgga acagagcccc tcttgcgtgt tatggcagaa
    28561 gcgcctacaa cagaagaagt agactactat gttgatacca tcacagatgt agttcgtgct
    28621 gaaattggga ttgattaaat cctagaaaac tagatgaaaa taaaaaatta tggtacaata
    28681 gcttataata ttgtagccga tggagaaaga catgaatctt aaacgtgaac aagaatttgt
    28741 tagtcagtat cattttgatg cgcgtaattt tgaatgggaa aatgaaaatg gagctcctga
    28801 aaccaaggtg gatgtgaatt tccaattgct ccaacatgac caagaaaatc aagtgacttc
    28861 cttgattgtc atcttgagct ttatgattgt atttgataag tttgtcatta gtggaacaat
    28921 ctcacaagta aaccatatcg atggccgtat tgtcaatgaa ccaaatgaat tgaaccaaga
    28981 agaggtggaa accttggctc gtccatgttt gaacatgctc aatcgtttga cttacgaagt
    29041 gactgaaatt gcattagact taccaggaat taatttggag ttctaatatg aaattagctg
    29101 ttttcacaga ttcctctgct tatctcagtg cagagacctt gcaaagagaa gacttgtttg
    29161 tcttggatat tcctgtcaat attgatggtg aggaatatgt cgaaggcatc aatctgtctg
    29221 ctgaggaatt ttaccaaaaa atggctcagg cttctgaatt gcctaagacc agtcaaccaa
    29281 gtattgccaa gttagatgaa atcttaactt cgctcaaaga acaaggctat acacatgcct
    29341 tggggctttt cctatcttct ggaatttcag gtttttacca aaatatccag tatatggtcg
    29401 atgactatga gggcttaacc attgctttcc cagacacttt gattacaagt gctcccctag
    29461 gcatcatggt tgaaagcgtc tttaattggc gtgatcaggg cgatgatttt gccagcattc
    29521 aggataagct agccattcaa atcagccgta cgtcagcctt tatcatggta gatgacttgg
    29581 atcatttggt aaaaggtgga cgtctttcaa atggggctgc cattttgggc aatttgctta
    29641 gcattaagcc aatcctttat tttaacgatc aaggtgtgat tgaagtttac gaaaaagttc
    29701 gtactgaaaa gaaggccacc aagcgcttaa ttgaaattat caaggaaaca acggcttcag
    29761 gtcaataccg ggtcattgtc attcatggga atgctcctga aaaggctgaa gaattgcgtc
    29821 agcatttgct tgattttggc ttgggttcgg atgtttcact tgctacattt ggtagtgtca
    29881 ttggaacgca cctaggagca ggaagtattg ctctgggtta tattccagtg atttagttgg
    29941 cgcttctagg ctagttaaga tgccttgtat cttagcaatt gaacacggac tacctgcttc
    30001 ttgaaaaaag atgcctgtct tgcctttcgt ggaaagtcag tgccattccc tatttttcag
    30061 gggcagctaa ggtcctttgt atcttgataa ttgaacacgc ctggaaccct gtgtgaaaaa
    30121 gatagttctt ccaagaagta gacacttctt gattggaatt cctattttca ctttgtgttc
    30181 ttacggactt tgtatcttag acaggagtag agatgagtat tcgagtaatt attgccggtt
    30241 ttaagggaaa gatgggccag gctgcttgtc agatggtatt gactgatcca gacttggact
    30301 tggtagcagt tttggatcct tttgagtctg agtcagaatg gcagggtatt cctgttttca
    30361 aggataaggc tgatttagct tgttttgaag cggatgtctg ggtagatttt actactccag
    30421 ctgttgccta cgaaaataca cgttttgctc ttgaaaatgg ctttgctcca gtagttggaa
    30481 cgactggttt cacgagtgaa gaaattgcag agctaaaaga attttctcgt acccaagact
    30541 tgggtggcct gattgcccct aactttgcct tgggtgctgt cttactcatg caatttgcga
    30601 cgcaggctgc caaatatttc ccaaatgtgg agattattga gctccatcat gacaagaaaa
    30661 aggatgctcc gagtggaaca gccattaaaa cagctgagtt gatggcagag attcgagagt
    30721 caattcagca aggtgcagca gatgaggaag agctgattgc tggtgctcgt ggtgctgact
    30781 ttgatggtat gcgcatccac tcagttcgtt tgccaggttt ggtagcccat caggaagtca
    30841 tctttggcaa tcaaggagaa ggattgaccc tccgtcatga ctcctatgat cgcatctcct
    30901 tcatgacagg agtcaatttg ggaattaaag aagttgtcaa gcgtcatgag cttgtctatg
    30961 gattagaaca cttattatga gattaatgca aatgccttct gaatttcaga aggctttacc
    31021 agtattagaa aaaattaaag aagcaggctt tgaggcttat tttgttgggg gctctgttcg
    31081 agatgccctt ctccatagcc ctatccacga tgtggatatt gcgacgtctt cttatccaga
    31141 agagaccaag cagatttttc cgcgaacagc cgatatcgga atcgagcatg gaaccgtctt
    31201 ggtcttagat ggggatgagg agtatgaggt aacaaccttt cggacagagg atgtctatgt
    31261 ggactatcgc agacccagtg cggtttcctt tgtgcgctcg ctagaagaag acctcaaacg
    31321 ccgtgatttc acagtcaacg cctttgcctt ggatgagaca ggagaaatcg ttgacttgtt
    31381 ccatggttta gaagatttgg aaaagcaagt cttgcgagca gttggagtgg ctagtgagcg
    31441 tttcaacgaa gatgctttac ggattatgcg tggtttccgt tttcaggcta gtcttggttt
    31501 tgcacttgaa ccagaaacat ttaaagctat gaagaccttg acgccgcttt tggagaacat
    31561 ttctgtagag cgtaccttcg tcgagtttga taaactcttg ctggctccat tttggagaag
    31621 ggggttggct tccatgattg agagtcaagc ttatgactat ctccctgata tggcatctag
    31681 ccaggacaag ctcaacagac tgtttgattt ggagactgat tttacttttg aatcctctga
    31741 acaagcctgg gcggctttac tatgggcttt ggagattgaa aatgcgcagt catttttgaa
    31801 atcttggaag acctcacgcc agtttgccaa gcaagttcag gatttgctga ttattttggc
    31861 tctgcgtgaa aatggagaat tgagcaagcg agattgttat cgctttgaca tagatttgct
    31921 tttacaggct gaaaatcttc gtcaagctca aggaaaagaa gtcaacccac aagccatcac
    31981 agaaaaatac caaagcttga ctatccatga caagaaagag attcagatta atggcggtat
    32041 tttgatcaag gaatatggct atcagccagg cccagacttg ggagagattt taacagagat
    32101 tgagtttgcc attgtcgatg gagaattgga gaataatcgt gaagccatcc atgcttacct
    32161 gagggagaaa aaatgagtga ttttatcgtt gaaaaactaa gtaaatctgt tggtgacaag
    32221 accgttttta gggatatttc ctttattatc catgacttag acagaattgg tttaatcggt
    32281 gtcaatggga ctggcaagac cacccttttg gacgtccttt ctggtgtttc tggctttgat
    32341 ggggatgtca gtcctttttc agctaaaaat gattaccaga ttggttactt gactcaggat
    32401 cctgattttg atgatagaaa gacagttttg gatacgattc tatctagtga actcaaggaa
    32461 atccagctca ttcgtgagta tgaattgatt atgctcgact atagcgagga caagcaggcg
    32521 cgtttggaac gtgtcatggc agagatggac tctctccaag cttgggaaat cgagagtcag
    32581 gtcaagaccg ttcttagcaa attgggcatt caagacttat ctactcctgt tggggaattg
    32641 tcaggtggtc tgagaagacg ggtacagttg gcacaagtct tacttggcaa ccacgacctc
    32701 ttgcttttgg atgagccgac caaccatctg gatattgcga ttattgagtg gctgaccctc
    32761 tttttgaaaa attctaagaa gaccgtcctt tttatcactc acgatcgtta tttcttagac
    32821 gctttgtcaa cacggatttt cgagttggag cgagcaggct tgacagaata tcagggcaat
    32881 taccaggact atgttcgcct taaggcagaa caggacgagc gcgatgcagc tctacttcat
    32941 aaaaaagaac aactctacaa acaagaactg gtctggatgc gcagacaacc gcaggcacgt
    33001 gcgaccaagc aacaagctcg tatcaatcgt ttccatgatc tgaaaaagga agtttcaggc
    33061 agtagtgctg agacagactt gactatgaac tttgaaacca gtcggattgg gaagaaagtc
    33121 atcgagtttc aggctgtttc ctttgcctat gaaaataagc ccattttgca agattttaat
    33181 ctcttagttc aggctaaaga ccgtattgga attgttgggg acaatggtgt tggaaaatca
    33241 accctactta acctgattgc aggaagtctt gagccgacag caggacaagt tgtgattggg
    33301 gaaactgttc gcatcgccta tttctctcaa caaattgagg gtttggatga aagcaagcgt
    33361 gtgatcaatt acctgcagga agtggcagag gaggtcaaga ccagtggtgg ttctacgact
    33421 tccatcgctg agttgctgga gcaattcctc ttcccacgtt cgacgcatgg gaccttgatt
    33481 gagaaattgt cagggggtga gaaaaaacgt ctttatctcc tcaaactgct tttggaaaaa
    33541 ccaaatgttc ttcttttaga cgagccaacc aatgacctag atattgcaac tttgacagtc
    33601 ttagagaatt tcttgcaagg ttttgcaggt cccgttttaa cagtcagtca cgaccgctat
    33661 ttcttggata aggtagcgac caagattctc gcttttgagg atggcaagat tcgtcctttc
    33721 tttggtcatt acaccgacta tcttgatgaa aaagcttttg aaacagatat ggccaatcaa
    33781 gtgcaaaagg ccgaaaagga aaaagtggtc aaggttcgag aagacaagaa acgcatgacc
    33841 taccaagaaa agcaggagtg ggcaagtatt gaaggtgata ttgaaacctt ggaaaaacgt
    33901 atcgctgcta ttgaagagga aatgcaggct aacggctctg actttggtaa gctggctact
    33961 ctccaaaaag aattggatga gaaaaatgaa gcactccttg aaaaatacga acgctatgag
    34021 tatctcagtg aatttgatag ttaatactat tcgaaaatca aagtgtaaac tatgtcggct
    34081 tcacattgcc gactcaagta cagcctgtgg ccggcttcct agtttgcact ttgattttta
    34141 ttgagtataa aagaatagaa aaatcccatc tcatgaacgg atttctctat tcttttttgg
    34201 tttcttgatg aaagatattt tgccaggttt cgtggcgacg ccagatactg gtatggatga
    34261 taccatctaa ctcatagcag atgagtttgg ttttttgact gatggaagta atttgaatgt
    34321 ccttgatagc agaatttaac tcttttttgg tcttataagc ctctttatcc atctgctctc
    34381 catcttggcg aatatagaca aaatcatcag tcaagagttc ttctagttgg tttccttggt
    34441 caatcaattg ttcacgcata agcaattttt tatagacatt gtctaaaatt tcatcctcag
    34501 ggataggtgc tggttcgata tggacatcgg tatcaaagac gccaaaacga ttctccagca
    34561 tagactcgac ctgatccgcg atttcatggc tttcaaaaac agacaagtca ggattcatct
    34621 ctagtgtaat atccaggtag atgttgctac cgtaggtgcg acctctttgc gatttgacct
    34681 tgctgatttt gggaatttcc atgatagcct tttggtagtc ctcgagcagg cggtcgtcaa
    34741 agccatctga aagactaaag gaagactcga tgaagatatc ataggcagtc ttcaagataa
    34801 agaaagtgat gatgatagca accagtttat ccacaatcgg ataattgaaa ctactagcta
    34861 ggatggcaat ggcggttcca agtgaggtaa cagcgtcaga aagattgtcc ttagcagctg
    34921 ctttcagcgc cttggagttg gatttcttac tgaggcgagt attgtagaga tagaccacaa
    34981 acataatcgc tgcagaaatg attcctagag ttgcaccaag aggatcaatg accgtttctt
    35041 cccgactgag aatcttttga atggtatctc ttagaacatc gaaaccgaca tagaacatga
    35101 tgatagaagt gatcaagctt gccaaatctt caatcttcca atgaccaaaa cggtggtcac
    35161 ggtctgcagg ctggcgcgcc atccgaatcc cgattaagag ggccacattt ccaatgatgt
    35221 ccgatacgtt attaaaacca tcggccacca aactggatga atgaaggaga tgaccagttg
    35281 ctaatttggc tgcagacaag atcaaatagg tcgaaatact gataatggct ccacgctcag
    35341 ctaacttgag atttgagata gattgcttca ttcaacttcc tttctagtca catagcattc
    35401 taccattata ctggttttca aggaaaaatt caaataaggc agtttttact ctttgaaaac
    35461 tccccaaaat ttggtataat agtactactc aagggagtag ctggcagaaa cctgtgatag
    35521 tgtcgtcatt ccgaatttta tgctgaaaag tatgctttcc ggccctatct taaacagcga
    35581 gacttgttat gattaacagg tctctttttg tttgtcgtga aaagatatga cagaaagaga
    35641 gtctgttttg cacacaatgt caaggaggag acacatgtca aaagaacaaa aacgccaagc
    35701 gttttatact cagagccctg aagaggtctt gcaggctgtg gatgcgaccg agcaaggttt
    35761 gtcgtcaagt gaggcggaaa agcgccttgt cgaatttggg cacaatgaac tcgaagaagg
    35821 cgagaaacga tcaatcttgg tcaaattcat cgagcaattt aaggatttga tgattatcat
    35881 cctagttgcg gcagcaatct tgtcagtcgt gacttctggt ggggaagata tcgcagatgc
    35941 cattatcatc ctagctgtgg ttatcatcaa cgctgccttt ggtgtttacc aagaaggaaa
    36001 agctgaagaa gctattgaag ccctcaaatc catgtctagt ccagttgccc gcgttcttcg
    36061 tgatggacac atggcagaga ttgactctaa agaattggta ccaggcgata tcgttgccct
    36121 tgaagcaggt gacgtggtac cagcggacct acgtttgata gaagccaact ctcttaaaat
    36181 tgaagaagca gccttgacag gtgaatctgt accagtcgaa aaagacttgt cagtcgagct
    36241 tgcgacagat gctggtattg gtgaccgtgt caacatggcc ttccaaaact caaacgtaac
    36301 ctatggtcgt gggatgggtg ttgttgtcaa tacaggtatg tacactgaag ttggtcatat
    36361 tgctggtatg cttcaagatg cggatgagac tgatacacca ctcaaacaaa acttgaacaa
    36421 cctttctaag gtcttgacct atgctatctt ggccattgcc cttgttactt ttgtagtggg
    36481 tgtcttcatt caagggaaaa atccacttgg tgagttgttg acttctgttg cccttgccgt
    36541 tgcagccatt ccagaaggac ttcctgctat cgttaccatc gttctttctc ttggtactca
    36601 agttttggcc aaacgacatt ccatcgttcg taagttgcca gcagttgaaa cacttggttc
    36661 aactgaaatc atcgcttctg ataagactgg tacgctgact atgaacaaga tgacagtcga
    36721 aaaagtcttc tacgatgcgg ttctacatga ctcagctgat gatattgaac taggtcttga
    36781 aatgccacta cttcgttcag ttgtcttggc caatgatacg aaaatcgatg tggaaggtaa
    36841 cttgattggt gacccaaccg aaacagcctt tatccaatat gccttggaca agggctatga
    36901 tgtcaaaggt ttcttagaga aatatcctcg tgtagctgaa ttgccatttg actctgaccg
    36961 taagctcatg tcaacagttc acccattgcc agatggtcgt ttccttgtag cagtcaaggg
    37021 tgcgccagac caactcttaa aacgttgtct tcttcgtgat aaggctgggg atattgctcc
    37081 gattgatgag aaggttacaa atctcattca tacaaacaat tctgaaatgg ctcatcaagc
    37141 cttgcgtgtc cttgcaggtg cttataagat tatcgatagt attccagaaa atctcacttc
    37201 tgaagagctt gaaaatgatt taatttttac tggtttgatt gggatgattg accctgaacg
    37261 tcctgaagcc gctgaggctg ttcgtgtggc taaggaagcg ggaatccgtc caattatgat
    37321 tacaggtgac caccaagaca cagcggaagc cattgccaaa cgtttgggaa tcattgacgc
    37381 aaacgataca gaaggtcacg ttttaactgg tgctgaactc aatgaactgt cagatgaaga
    37441 atttgaaaaa gtcgttggtc aatactctgt ttatgcccgt gtgtctccag aacacaaggt
    37501 tcgtatcgtc aaggcttggc aaaaacaagg taaagtcgtt gccatgacag gtgacggtgt
    37561 caatgacgcg ccagctctga aaacagccga tatcggtatc ggtatgggaa tcactggtac
    37621 agaggtttct aagggggctt ctgatatgat tcttgcagat gataactttg cgactattat
    37681 cgtcgcagtg gaagaaggac gtaaggtctt ctcaaacatt caaaagacta ttcagtacct
    37741 actttctgct aatactgctg aagtattaac catcttccta tcaaccttgt ttggttggga
    37801 tgtcttgcag ccggttcatc ttttgtggat caacttggta acggatacct tcccagctat
    37861 cgctcttggt gttgaacctg cggagcctgg tgtcatgaat cataaaccac gtggacgcaa
    37921 ggcaagcttc ttctcaggtg gtgttttgag ttctatcatt tatcaaggtg tactccaagc
    37981 agctcttgtt atgagtgttt atggccttgc gattgcttac ccagttcatg tgggtgacaa
    38041 tcatgctatt catgcagatg ccctaacgat ggcctttgca acccttggtt tgattcagct
    38101 cttccatgcc tacaatgtca agtctgtcta ccaatccatc ttgacagttg gcccattcaa
    38161 gtctaagacc tttaactggt ccatcttggt atcttttatc cttctcatgg caacaatcgt
    38221 tgtagaaccg cttgaaggaa tcttccacgt aaccaaacta gacttgtcac aatggggaat
    38281 tgttatggct ggaagcttct caatgattat catcgtcgaa atcgttaagt ttattcaacg
    38341 caaactcggt tttgacaaga atgcgattta agggaggttt cggatgtcag catatcaatt
    38401 accgaccgta tggcaggatg aagctagtaa tcaaggagct tttacggggc taaacagacc
    38461 aacagcaggt gcccgtttcg aacaaaactt gccaaaagga gaacaagctt ttcagcttta
    38521 ttcactggga acaccaaatg gtgtgaaggt tactatctta ttggaagaat tactagaagc
    38581 tggttttaag gaagcggctt acgacttgta taagattgct atcatggatg gggatcaatt
    38641 cggctcagac tttgtgaagc tcaatccaaa ttccaagatt ccagccttat tggaccagtc
    38701 aggtactgaa aacgtaagag tctttgagtc tgctcatatt cttctttacc ttgctgagaa
    38761 atttggagcc tttttaccaa gtaatcctgt ggaaaaggta gaagttttga attggctatt
    38821 ctggcaagca ggtgcagcac cttttctagg tgggggattt ggacatttct tcaattatgc
    38881 tcctgaaaaa ttggaatatc ctattaaccg ttttacgatg gaagtgaaac gccagttgga
    38941 tttattggat aaggaattgg ctcagaaacc ttatattgca ggcaatgact atacgattgc
    39001 agatattgct atctggtctt ggtatggaca gttagttcaa ggaaatcttt accaaggttc
    39061 tgcaaaattc ttggatgcct caagttatca aaatctagta aaatgggcag aaaaaattgc
    39121 caatcgtcca gctgttaagc gtggattgga agtaacttat acagaaatta aatagcaaaa
    39181 aagtcatctt cggatggctt tttgctacag ttgagggaaa gggtttgcag ttatcggctt
    39241 ttgtgctata attgctataa tatagtaaaa agcaagagga gtgtgaggaa gtggaaaaga
    39301 aaattgtgaa ggatatctta tttttatctc aagtgtctca gccggcaagt caggaggacc
    39361 tttatcttgc cagagatttg caggatacac tcttagcaaa tcgtgatacc tgtgttggtc
    39421 tagctgccaa tatgattggg gtgaagaagc gcgtgattat ctttaatctt ggcttggttc
    39481 ctgtggtcat gtttaaccca gtgcttctgt cctttgaagg atcctatgag gcagaagaag
    39541 gctgtttgtc cttggtaggt gtgagatcaa ctaagcgtta tgaaaccata aggcttgcct
    39601 atcgtgacag caagtggcag gaacagacca ttaccttgac aggcttccca gctcagattt
    39661 gccagcatga gctggatcac ttggaaggac gaatcattta ggaggaaagc aaatgaaacg
    39721 aatagtcttt gaacttattt ttatcgcaac gacctggtat atctttttac cgccccttaa
    39781 cctgaccagc tgggaatttc tcttcttcct ctgtgggcat ttgttagttg tggcaatatt
    39841 atttggcttt ggcaagggga taaaccttgt caaaacggtt catgtgcgcc acggtaaggc
    39901 ggaagctgcc ttaaatcttg agggtttcaa aatcaatcgg ttagggaaaa ttctgttagc
    39961 ttcgattgga ggaattcttc tcttggcagc tttggtttcc ttggtaactt ccagcatgtt
    40021 tcaggctaaa aattatgcca atgtagtcac ggttacggaa aaagacttta ctgaatttcc
    40081 taagagtgac accagtaagg ttcctatcct agatagaagt actgctgaaa aaattggaga
    40141 ccgctacttg ggttccctaa ccgataaggt gtcgcaatac gtagcggcag atacctatac
    40201 ccaattgaca attgatggga aaccttatcg ggtcacacca ctagaatatg cagaccctat
    40261 caaatggttt aacaatcaag ccaagggaat cggtgagtat attaaggtgg acatggtaac
    40321 tggaaatgcg gatttggtgg acttgaagac accaatcaag tattcagact cggagtattt
    40381 taaccgtgat gtcaaacgtc acctgcgctt gaagtacccg accaaaatct ttaaaactcc
    40441 atcttttgag gtggacgatg agggcaatcc tttctatgta gcaacggttt accaaaagca
    40501 atttggactt gctgttcctc gtcctgcttc agtcattatc ttggatgcta caaatggaga
    40561 aaccaaggaa tacagcttat cagatgttcc agaatgggtg gacaggatct atccagcaga
    40621 ggaaaccatt gagcaaatca actacaacgg caagtacaag gacggtttct tgaatgccat
    40681 gatttccaag aaaaacgtga cccagactac caatggctat aattacttgt ctatcggtaa
    40741 tgacatctat ctctacacag gtgtgacgtc ggctaatgcg gatgagagta atcttggttt
    40801 catccttgaa aatatgcgaa caggagaaat cactaagtat agcttggctt ctgcgacaga
    40861 agaatcagcc cgtgaatcag cagaaggtgc tgttcaggag aaatcctaca aagcaacctt
    40921 cccaatcctc atcaacctca atgacaagcc tctctacatc atgggcttga aggacaatgc
    40981 tggcttggtc aaagagtacg ccctggtaga cgcagtcgag taccaaaatg ttatcgttgc
    41041 tactacagtg gaagagatgc tcagcaagta tgccaataaa aacgaccttg aaattgacaa
    41101 tgcaacgaca gaaagcatca atggagtagt agcagacctc aaatcagctg ttatcaaggg
    41161 agacactgtc tacttcttta aagttgatgg caagatatac aaggtcaagg cttcagtatc
    41221 cgatgacctt ccttaccttg aaaatggtaa aaccttcgaa ggtcaagtag gaaaagacaa
    41281 ttatctcaag acctttaagc tacggtaaaa ataggttttt ttcagaaagt atatgttata
    41341 ataaggtaaa ttaagcctaa tggaggacaa agaaatgggt ttttatttga tggttgcttc
    41401 aatgctactc ggactgctcg ctttgaagat aggtttttct cagttcaagg agaaaaaaga
    41461 taaattctta tctatcttaa caagtttagc tggcacagcc cttgttctcg tggctgtctg
    41521 gttaggatgg cccaaataaa tagaaaaacc tcggtcaaac cgaggttttt caaatgaatt
    41581 tcttggttgt ggctaaaaaa tatgctacac tatcaatatg aaaattttaa tcccaacagc
    41641 aaaagaaatg aacacagact tgccaagtat cgaggcaatt cctttaaaac cagaaagtca
    41701 ggccgtgctt gatgccttgg ctctctattc tgccagtcaa ttggagagtt tctacaaggt
    41761 atcagctgag aaagcggcgg aagaatttca aaatatccaa gctttgaaaa ggcaaactgc
    41821 tcaacactat ccagccttga aactttttga tgggcttatg taccgcaaca ttaagagaga
    41881 taagctgacc gaggcggaac aagattatct tgaaaatcat gttttcatta cctcggcttt
    41941 gtacggtgtt gttccagtct tgtcacccat ggctcctcac cgtttggatt ttttgatgaa
    42001 attaaaagtc gctggtaaga ctttgaagag ccattggaag gcagcctatg atgaaactct
    42061 gaagaaggaa gaagtgattt tctctctctt gtcatcagag tttgagactg tattttctaa
    42121 ggaaatcaga gcaaagatgg tgaccttaaa attcatggag gatagaggcg gtcagctgaa
    42181 gattcactca actatctcca agaaagcgcg cggggccttt ctaacagctt taatagaaaa
    42241 tcaagtacaa actgtggggg aagcacgtcg cttgaacttt gctggatttg tttaccgaga
    42301 agatttgtca caaccacagg gattggtttt tgtaaaggaa gtatagaaat cagatatttt
    42361 gtatttggca atatgtatca tcagctattt tagtttataa atgagaaaaa agcgaacaag
    42421 ctagtcttct gagtgtcaga aaagtagtct tgttcgcttt tattatgtta tactcttcga
    42481 aaatctcttc aagccacgtc agtgtcgcct taccgtatat atgttactga cttcgtcagt
    42541 tctatctaca acctcaaagc agtgctttga gtagcttgcg gctagcttcc tagtttgctt
    42601 tttgattttt attgagtgtt agttacttga tagcttcgac caagtcttga gcttgttttt
    42661 caagtgagtt taggactgtt tcttcaagaa ccaattttcc gtctgcccag gcagagtcat
    42721 taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg gataaatggc aagaggtctt
    42781 tgtagatagc gaaaagttga tcgtgccctg cattggctac agatgatact gtgacaaact
    42841 tgtcttgaag ggcagaaacg ccacgtgtat cagacaagtc aagggcacga gatagccagt
    42901 caagcaagtt tttcactgta ccagggatag agaagttgta gactggagag aaaatccaga
    42961 tagcatccgc aacgagaact gcttcacgag cagcagctac agctggatgt gttggaactt
    43021 ccaaatcttg gctgaagaga ggaagggctg aataatcaag gtagctaact tccgctttac
    43081 cagcaagtgc tttctcagct tcgagcgcca tttggtggtt gaaagaacct tgacgtagtg
    43141 atccgacgat aaataatact tttttagaca tgatgtgtct cctttttctt aaaatttcga
    43201 gaactctctc gttgttataa aatatattac aacaaaacaa aagaacttgc aagaaatttg
    43261 ctcagagttt atttgaaaat tgtaaaattt cggaaactct agtcatttgt gactgaaaaa
    43321 gtaagaactg tttcactttc aaaatcggtt ttgtttgaag ggagaaatag aat
//
LOCUS       DAVBNN010000013        43039 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBNN010000013 DAVBNN010000000
VERSION     DAVBNN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.013"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(15..1535)
                     /locus_tag="VQ847_000737"
     CDS             complement(15..1535)
                     /locus_tag="VQ847_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3050116.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(1528..2256)
                     /locus_tag="VQ847_000738"
     CDS             complement(1528..2256)
                     /locus_tag="VQ847_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050117.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(2271..3035)
                     /locus_tag="VQ847_000739"
     CDS             complement(2271..3035)
                     /locus_tag="VQ847_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3050118.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(3039..3482)
                     /locus_tag="VQ847_000740"
     CDS             complement(3039..3482)
                     /locus_tag="VQ847_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3050119.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(4164..4460)
                     /locus_tag="VQ847_000741"
     CDS             complement(4164..4460)
                     /locus_tag="VQ847_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3050120.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(4482..5546)
                     /gene="pepA"
                     /locus_tag="VQ847_000742"
     CDS             complement(4482..5546)
                     /gene="pepA"
                     /locus_tag="VQ847_000742"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3050121.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            5948..6649
                     /gene="galE"
                     /locus_tag="VQ847_000743"
     CDS             5948..6649
                     /gene="galE"
                     /locus_tag="VQ847_000743"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3050122.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            7072..8031
                     /locus_tag="VQ847_000744"
     CDS             7072..8031
                     /locus_tag="VQ847_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050123.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            8021..8977
                     /locus_tag="VQ847_000745"
     CDS             8021..8977
                     /locus_tag="VQ847_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3050124.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            8974..9726
                     /locus_tag="VQ847_000746"
     CDS             8974..9726
                     /locus_tag="VQ847_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3050125.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            9822..10787
                     /locus_tag="VQ847_000747"
     CDS             9822..10787
                     /locus_tag="VQ847_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3050126.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(11012..11254)
                     /gene="yidD"
                     /locus_tag="VQ847_000748"
     CDS             complement(11012..11254)
                     /gene="yidD"
                     /locus_tag="VQ847_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3050127.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(11254..11976)
                     /locus_tag="VQ847_000749"
     CDS             complement(11254..11976)
                     /locus_tag="VQ847_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3050128.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(11963..12532)
                     /locus_tag="VQ847_000750"
     CDS             complement(11963..12532)
                     /locus_tag="VQ847_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3050129.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(12551..13279)
                     /locus_tag="VQ847_000751"
     CDS             complement(12551..13279)
                     /locus_tag="VQ847_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3050130.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(13279..14019)
                     /gene="xerD"
                     /locus_tag="VQ847_000752"
     CDS             complement(13279..14019)
                     /gene="xerD"
                     /locus_tag="VQ847_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3050131.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(14010..14471)
                     /locus_tag="VQ847_000753"
     CDS             complement(14010..14471)
                     /locus_tag="VQ847_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3050132.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(14468..14989)
                     /locus_tag="VQ847_000754"
     CDS             complement(14468..14989)
                     /locus_tag="VQ847_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3050133.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(14965..15936)
                     /locus_tag="VQ847_000755"
     CDS             complement(14965..15936)
                     /locus_tag="VQ847_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3050134.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(15933..16727)
                     /gene="racE"
                     /locus_tag="VQ847_000756"
     CDS             complement(15933..16727)
                     /gene="racE"
                     /locus_tag="VQ847_000756"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3050135.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(16934..17182)
                     /locus_tag="VQ847_000757"
     CDS             complement(16934..17182)
                     /locus_tag="VQ847_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3050136.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(17324..18949)
                     /gene="treC"
                     /locus_tag="VQ847_000758"
     CDS             complement(17324..18949)
                     /gene="treC"
                     /locus_tag="VQ847_000758"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3050137.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(19127..21094)
                     /gene="treP"
                     /locus_tag="VQ847_000759"
     CDS             complement(19127..21094)
                     /gene="treP"
                     /locus_tag="VQ847_000759"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3050138.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            21279..21989
                     /gene="treR"
                     /locus_tag="VQ847_000760"
     CDS             21279..21989
                     /gene="treR"
                     /locus_tag="VQ847_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3050139.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(22022..22825)
                     /locus_tag="VQ847_000761"
     CDS             complement(22022..22825)
                     /locus_tag="VQ847_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3050140.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(22838..23715)
                     /locus_tag="VQ847_000762"
                     /pseudo
     CDS             complement(22838..23715)
                     /locus_tag="VQ847_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(23727..24665)
                     /locus_tag="VQ847_000763"
                     /pseudo
     CDS             complement(23727..24665)
                     /locus_tag="VQ847_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(25156..26082)
                     /locus_tag="VQ847_000764"
     CDS             complement(25156..26082)
                     /locus_tag="VQ847_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050141.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(26093..27160)
                     /locus_tag="VQ847_000765"
     CDS             complement(26093..27160)
                     /locus_tag="VQ847_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050142.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(27169..28095)
                     /locus_tag="VQ847_000766"
     CDS             complement(27169..28095)
                     /locus_tag="VQ847_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050143.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(28095..29591)
                     /locus_tag="VQ847_000767"
     CDS             complement(28095..29591)
                     /locus_tag="VQ847_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050144.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(29658..31637)
                     /locus_tag="VQ847_000768"
     CDS             complement(29658..31637)
                     /locus_tag="VQ847_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3050145.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(32323..33516)
                     /locus_tag="VQ847_000769"
     CDS             complement(32323..33516)
                     /locus_tag="VQ847_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3050146.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(33654..35096)
                     /gene="gtfA"
                     /locus_tag="VQ847_000770"
     CDS             complement(33654..35096)
                     /gene="gtfA"
                     /locus_tag="VQ847_000770"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3050147.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            complement(35373..35453)
                     /locus_tag="VQ847_000771"
                     /pseudo
     CDS             complement(35373..35453)
                     /locus_tag="VQ847_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(35454..36287)
                     /locus_tag="VQ847_000772"
     CDS             complement(35454..36287)
                     /locus_tag="VQ847_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3050148.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(36301..37167)
                     /locus_tag="VQ847_000773"
     CDS             complement(36301..37167)
                     /locus_tag="VQ847_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3050149.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(37181..38440)
                     /locus_tag="VQ847_000774"
     CDS             complement(37181..38440)
                     /locus_tag="VQ847_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3050150.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(38532..40694)
                     /locus_tag="VQ847_000775"
     CDS             complement(38532..40694)
                     /locus_tag="VQ847_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3050151.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            40802..41662
                     /locus_tag="VQ847_000776"
     CDS             40802..41662
                     /locus_tag="VQ847_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3050152.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            41659..42594
                     /locus_tag="VQ847_000777"
     CDS             41659..42594
                     /locus_tag="VQ847_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3050153.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(42720..42807)
                     /locus_tag="VQ847_000778"
     tRNA            complement(42720..42807)
                     /locus_tag="VQ847_000778"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42771..42773),aa:Ser,seq:gct)
     gene            complement(42814..42887)
                     /locus_tag="VQ847_000779"
     tRNA            complement(42814..42887)
                     /locus_tag="VQ847_000779"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42851..42853),aa:Ile,seq:gat)
     gene            complement(42923..42993)
                     /locus_tag="VQ847_000780"
     tRNA            complement(42923..42993)
                     /locus_tag="VQ847_000780"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42959..42961),aa:Gly,seq:tcc)
BASE COUNT        12925 a         9680 c         7979 g        12455 t
ORIGIN      
        1 aagtctctgt cccatcattt cttcaacaaa ccttgttctt ggagaaactc cttggctact
       61 tgctttgctg acttgccttc aacaccgact tggtagttga gctggctcat ctggctttct
      121 gtaatcttac cagccaatgt attaagaact ctttccaact ctgggtgttt cttgagaaga
      181 gcttctttca tgagtggagc cccttgataa ggtgggaaga gttgcttgtc atcttccaag
      241 acctgtaaat cataacgctc caattccgca tcagtcgaat aggcatccgt gatttgaata
      301 tcccctgact gaattgcctg ataacgaaga gctggctgca tagtcgccac attgagattg
      361 agaccataca ttgattgcaa gcccttattt ccatcttcac ggtcgttaaa ctcaagcgta
      421 aagcctgcct tcagctgccc ttccactttt ttcaaatccg aaatggtctt caagccatat
      481 tcttgagcaa tctttttcgg aacagctaca gcataggtat tttgataaga cataggtttg
      541 agataggcta gatgatcctg cttggcaatg ccatcacgcg ccacttgata aacctgctct
      601 ggctcatgac tcaccttggg tgatggttga agcaaacttt cagtcaccgt accggtaaat
      661 tcaggataaa tgtcaatatc accttttttc agagcttcat aaaggaaact tgtcgtccca
      721 aaattcggtt taacagtcgc agtcatgctg gtattttctt caatcagcaa tttatacata
      781 ttagccaaaa tttctggttc tgggcctatt ttcccagcaa taatcaagtt ttccttctct
      841 ttttgagcca aaagggctgg actataagac agacccagta ataaagccac caaggcaaaa
      901 ccagagaaaa tcgtccgcaa tttcgctttt tccattactt ttagtaggaa gttaaaggca
      961 atagctagca ctgcagaaga aagggcccca atcaaaatca aactggcatt attacggtca
     1021 attcccaaca ggataaagga acccagtccc cctgccccaa tcaaggtcgc caaggtagcc
     1081 gtaccgataa tcaagaccgc tgccgtccga attccagaca tgataacagg catggcaagt
     1141 ggaatttcaa acttcttgag acgctcccat ctggtcatcc caaaggcaat cccagcctct
     1201 tgaagactcg gatcaattcc cttcagccca gtaatagtat tttgtaaaat cggaaaaatc
     1261 gcataaatca ctagagctgt caaagccggc aaggtcccaa ttcccatcaa agggataaag
     1321 agccccaaca aggccagaga cgggatggtc tggaaaatac ctgcaatctg caagacccag
     1381 tcggccagct tctcatgata gcgaagaaaa acagccaagg gaatcgcaag caaaatagct
     1441 agtaacaagg tcaaaagtga caactgcaaa tgttgagata gagctgtcaa ccaatcacta
     1501 aaacgatcct gaaaagttgc aattaaatta gtcatgaaca ctacctccaa acaagtctgc
     1561 tacaaagtct gttgcaggca cttttaaaat tgtctcggga ttcgctacct ggcgaatttc
     1621 tccatcctgc aagacagcaa tacggtccgc caacttcaag gcttcatccg tatcatgggt
     1681 tacaaaaatc gttgtcatcc caaactcttt atgcaattct tttgtcagaa cctgcaactg
     1741 ttttctcgaa atagcatcca aggccgaaaa gggttcatcc atgaggaaaa tcttgggctg
     1801 accaatcata gctcggacaa taccgacccg ttgctgttct ccaccagata attcactagg
     1861 taagcgatgc ccatactcgg ctactggtaa accaacctta gccaaaagct cttctgtttt
     1921 cttcgtaatt tcttccttgc tccacccctt catttcagga atgagagcaa tattttccgc
     1981 aactgttaga tttggaaaaa gagcaatagc ctgtaaaaca taaccagtag aaagacgaag
     2041 ttcacgctca tcatagtctt tgatgcgctt cccatccata taaatatttc catcagttgg
     2101 ttccaaaaga cggttaatca tcttgagcat ggtcgtctta cctgacccag aaggccctac
     2161 taaaaccata aattccccat cctcaatctg taagttgaca tctctcaaga catccttttc
     2221 tgtgtagcgc agtgctacat ttttgtattc aatcattctt tgtcctcaat ttaaaacttc
     2281 cctcgattag tcaagtcttc taccttaggc atgacttcct tattatccca atgctccaca
     2341 attttcccgt tctctaaacg gaagatatcg tactgggcat aagcaacgcc atcaatctga
     2401 gtctgaccat agctaaccac atagtttcct tgtcctaaga gttggaaaac aaagtcaaaa
     2461 gtgacactat attcagccac atagttttta taagcagcac ttccttgtcc aatctcatga
     2521 ttatgctgaa tcaaatcgtc tgccacataa tcactccact gctctagctc cccattttgg
     2581 aaaatttctg tcaagaaacg gcgaaccagt tttttatttt ctgctttctt gtccaaatcc
     2641 ttgatttcaa aatctccaaa aatttgatct agttgatcat tttcaggtgt tcgatagtag
     2701 tcaatgacat cccaatgctc aacaatacga ccattctcat ccgcacggaa agtatccgtc
     2761 gtcacccatt gagcttctcc accattcaga tattgatgaa catgaacaaa gaccagattg
     2821 ccatcctcaa tggtgcggac aatcttaatc tgacgctctg gatgacgctc aaagaaatct
     2881 gcaaagaagg ctgcaaatcc ttctttcccg tcaggaacac ctgtcgaatg ttggatatag
     2941 gtatccccta cagactgggc ttgagcctca gcaactcgtc cgtcttgaat ggcatggatg
     3001 tataggttgt gagcattttt cacttgttgt gacatattct aaacctcatt tcccttctct
     3061 ttcaaattcg ccaaaattct ttcttgaaaa ccttcaaatt ggtgaatttc ttcctctgaa
     3121 aatcctttgt aaaagatagt atccaatttc tgactgacac gatgccccac ttctttctgg
     3181 gacttgccta actccgttaa aactaaatac ttcttacgct tgtcttttcc acacggacta
     3241 acaattacaa gcttttgttc ctctagcttt tttatcatag tcgttagcgt attattcgca
     3301 agcccagtcg caagcgcgat atctgtcgca gttgcgcagc cagtttcact attccataaa
     3361 accgctaaaa tcttgccctg ttcaccccta taaagagcct caggatcttg actcagtaac
     3421 ttttgaaaaa tccgcccatt caacaaacga atatgatggg ctagcaaatg accatctttc
     3481 ataacacctc caatttattt cgatatcgaa atgaataaaa caattgtaac actcatcgtt
     3541 ctaactgtca actatttcga tttagaaata atttttgata attatccaca ccaccatact
     3601 ccggctcaac taacttttaa cgagagtttc taaactcctt cgtcctccag tctacaaaag
     3661 ccttccattc gtactatcct atattttatg aggggacaca tttttcctat cagaccattt
     3721 attttaaaga tagaagtaaa tcataattgc ttccatctgt tcttttatag tatattgaag
     3781 ttagactaga gcactgtatc ttctaaaaca ttgatagaaa gcgatttgaa tttcccaatc
     3841 aatttgttcg tatttatagc atttcgaaac tggaatagga caccatgact gctaaaagat
     3901 ttctataaat tcatttaatt tcctcaatca atttgttcat atcttatttc attccgctat
     3961 aatttcacct taccctatct ttttcgtagc acccttcaaa cagcctatcc cctaccgttt
     4021 gacgattcct cacttcgctc cacttccatt acagaagttt cttcactact atgggctcgg
     4081 ctgacttctc atgattcctt gttactacta tttgaacgct cacgagatag atcttacaaa
     4141 aaatgctttg atccacaatg gaatcaaagc attttaaaga gttcctcata cataagcgca
     4201 gaagtcgcag ttcctctgta cttggcttct tctcttttga taaagcgagc caagttgagc
     4261 aactcaggtg ctggatgttt gggatttagg agcaattcac gattgaccag gcctgagaga
     4321 cgaactgcct gcaattgctc atttgtagta ggcagttttt tagcagtctc taggagagca
     4381 gcaactaaat cttcactcaa atcatgtcga gcatgattgt aaagatcttt tataaggctt
     4441 tctaagtttg gttctgccat ccctaccacc tcccttatgg tttaataatg tttaatcaaa
     4501 tcaaccgttg aacgatccaa tttcttcacc aaggcttgta agaaagcttg cgcttctagg
     4561 aagtcatcca ttgcatagag ggtttggtga gaatggatat aacgagcgca gacaccgata
     4621 gttgttgatg ggacaccacc atttttcaga tgagctgcac ctgcatctgt tccgccttta
     4681 ccacagtagt attggtactt gataccagct tcttcagccg ttgtcaaaag aaaatccttc
     4741 atccctggga gaagcaagtg acctggatca tagaaacgaa tcaaggttcc atctccaatc
     4801 ttgccttgac caccgtagac atcacctgct ggtgagcaat caactgcgag gaagacttct
     4861 gggtcaaact tggttgtaga ggtatgagcg ccacgcagac caacttcttc ttggacgtta
     4921 gaacccagat agagttcatt gccgagtttt tgacctgata aagcttcagc tagctcgctt
     4981 accatgagga caccgtagcg gttatcccaa gcttttgaga tgatattttt ttcattggct
     5041 gtcaaaattg cagaactatc tggtacgatg gtatcaccag gacggatgcc aaaactttct
     5101 gcctcatcct tgtccgcaaa accaccatca aaaacgatat cggcaatggc tggcatggtt
     5161 ggtcccccct ttccacgagt caaatgcgga ggaacagaac ctgaaatcac aggaatttca
     5221 tgaccatcac gagtcaagag tttgaaacgt tggctgctaa ctaccatggg gttccagcca
     5281 ccgatttcta cgacacggaa ggtaccatct ggcttgattt cgctgaccat aaaaccaact
     5341 tcgtccatat gagaagcgac caagacgcgc ggtgcatcca cagcttctga atgtttgata
     5401 ccaaaaatac cacccaagcc atctgtcacc acttcatcca catgcggtgt caacttttca
     5461 cgaagataag cacggacagg cgcttcatga cctgagactg cagcaagttc tgttacttct
     5521 ttaatttttg aaaataatgt tgtcatttca gttccttctt tctttcatcc attttaccac
     5581 tttttatagg agaaggatag tgggaaggtg gatttctaag ttagtatctt agtcctgctc
     5641 tatcttagaa aaggatagta ttctcttgca tgtagtgcaa aatctagtaa acattccaaa
     5701 attaactcga atatttattt ccaaacaaaa aaaacaatac accatcaaag ttgtttggat
     5761 ttttcatgaa atttacagaa aatagttgac ttccctttct tctttcttta aatatatagt
     5821 tggttgagtt tggaatagta cgctgtagct gctgaaacat ttctagaaat taattcgact
     5881 ttcctaatag agttgttcat atcttatttc aatttactat agtacaaaac tagaaaagga
     5941 aaaaatcatg accaaaacaa ttcttgttac aggtgggact agctacattg gctcccatac
     6001 cgttaaagct cttttaaatg ctggctatca ggtgcatgtc ctcgataatc tctccacagg
     6061 aaatcgagcg gctgtggata gtcgtgctag ctttaaagaa ctggatgttt atgatgctag
     6121 cgccttaaag gcttacttag aagaaaatca gattgatgct gtcctccatt gtgcaggtga
     6181 aattgttgtg agcgaaagta ttgaaaatcc aagtaaatac ttcactgcca acgttgctgg
     6241 tatgaaccaa gttctcaaag tcttatctga agttggcatt caaaaaatca tgttctcttc
     6301 gactgcttct ctctatggaa ataactgtat tgacaagccg gtgactgaag ataccctgct
     6361 cgaccctgtc aacccttatg cagagacaaa actgatgggc gaacgaatga tttactggat
     6421 ggccaatcgc tacgactgga aatatgttat tttccgttac tttaatgttg ctggggctga
     6481 aatggatgct tcaaacggtc tgcgtgtgaa aaatccaact cacatcattc caaatatcaa
     6541 caagaccgca ttgggacaac atgatagctt aaaaatattt ggagatgact acgatacacg
     6601 tgacggttca tgtattcgag attacattta tgtcttggac cttgcatagg ctcatgttaa
     6661 aggaatgaac tacctatttc aagaagacag ttcttctcaa atctttaact taggaactaa
     6721 aaaaggctat actatcaaag aaatctttaa aactgctgaa gaattactaa attaaaaaat
     6781 cccacacgag attgttgctc gacgtgctag tgacccagcc agtgtcctag cagatgcttc
     6841 aaaagctaaa caatatcttg attggacggc tagctactcc ctcgaagata ttattttatc
     6901 agattaaggt aaaaacattt tagaatagga taacaaagga gaaagtcttg ttgctctctc
     6961 cttgttgtat ttattaaatt gtcagaaatt ttattgacag attagaaaaa taatgttaca
     7021 tttatatccg cagatatctt tcgataccaa atctacatga aaggacgggg tatgaaactt
     7081 tctcattatt taattggctt acttctactc ctagtctttc tctctattag cattgggacc
     7141 agtgattttt catggggaaa gctatttgat ttcgaccagc agacctggct cctctttcaa
     7201 gagtcccgtc tcccaagaac tatcagtatt ctcctgactg cctctagtat gagtatggca
     7261 ggccttctca tgcagactat tacccaaaat cagtttgctg caccgagtac agttggaacg
     7321 actgaagccg ccaaactggg aatggtgctg agcctttttg tctttccatc ggctagtctg
     7381 acccaaaaga tgctcttcgc ttttgtttca tccatcgtat tcaccctctt cttcctagcc
     7441 tttatgacca tttttactgt aaaggaaagg tggatgttgc ctctgattgg gatcatctat
     7501 agcgggatta tcggctcagt cacagaagtt atcgcctatc gtttcaatct ggttcagagt
     7561 atgactgcct ggacccaggg ctccttctcc atgattcaga cccatcagta tgagtggctc
     7621 ttcttaggcc tcatcatcct gataaccgtt tggaaattat cccaaacctt caccatcatg
     7681 aatctgggga aagaaaccag cgagggtttg gggatttcct actccctact tgaaaaactg
     7741 gccctctttc tggtggcgct aacgacaagc gtcaccatga ttaccgtggg tggcttacca
     7801 tttctcggag ttatcgttcc caatcttgtt cgcaagcgct atggagataa tctaagtcaa
     7861 accaaactca tggtcgcact ggttggtgcc aatctagttc tggcttgcga tatcctatcc
     7921 cgagttctga ttaggcccta tgagttgtct gtcagtctct tgctaggaat catcggtagt
     7981 ctcgtcttta tcctacttct ctggagaggg ggacgaaaag atgcagacta aaagcaaaca
     8041 taccaagctc ttctggattc tcattattct tgccatcgga gcttgtcttc tctacttttg
     8101 gcccatcact cacttgtcag cctttgcttg gaagttgcgt tcccaaaaga tcatcgttta
     8161 tctcttggta gccatcgcga ctgggatttc gaccattagt tttcaaaccc tgacggaaaa
     8221 tcgcttcctg acgcctagta ttttgggaat tgaatccttc tacgtcctac tacaaaccct
     8281 actactggtt tttgaaagca agtttcttca actgggcaaa tcccctatct tagaattcct
     8341 agtcttactt cttgtccagt ccctcttctt tctcgcctta caaggttact tgaagacact
     8401 gatgaagcaa gacctggtct tcatcctgct gatctgtcta gcgctcagaa gtctctttcg
     8461 aaatatcagc accttccttc aagtcctaat ggatccaaac gaatacgata aactgcaaaa
     8521 tagtcttttt gcctcctttc aacatcttaa cacttccatc ctagccatcg gttctctgat
     8581 catcctcgct ttgacaatct ttttctttcg aaaagcagtc gttctagatg tcttgcacct
     8641 gcaaagagaa acggctcaga tattgggact cgatgttgaa aaagaacaga aagagctcct
     8701 ctggggaatc gtgcttttga cctcaacggc cactgccttg gtaggaccta tggccttctt
     8761 cggctttatg ctggccaacc tcacctacct gattgtcaaa gactatcagc acaagttact
     8821 ctttatagtg gccattctgg ttggatttat tagcttaacc ttggggcaag ccttgattga
     8881 acgagtcttt gcactggaaa ttcgtatcag tatgatcatt gagagtgtgg gtggcttctt
     8941 attctttatc ttactatata ggagggctcg tcagtgaaac tggaaaacat tgacaaatcc
     9001 attcaaaaac aggatatttt gcaaggcatt tcgcttgaag tcagtcctca aaaactgaca
     9061 gcctttattg gtccaaatgg tgctggaaaa tcgactctcc tctccatcat gagcagacta
     9121 accaagaaag atcagggagt tctcagtatc aaaggacgtg aaatcgagag ctggaattcg
     9181 caagaactgg cccaagaact aaccatccta aaacagaaaa tcaattacca agccaaattg
     9241 actgttgaag aactggtcag ttttggacgt tttccctaca gccgaggtcg acttagatca
     9301 gaagactggg aaaaaatccg agaaactctg aactatttgg aactgaccaa cttaaaagac
     9361 cgctacatca atagcctgtc aggggggcaa ctccagcgcg tctttatcgc tatggtactg
     9421 gcccaggata cggactttat cttgctggac gaaccactca acaatctcga tatcaagcaa
     9481 agcgtcagca tgatgcagat tcttcgacga ctggtggagg aactcggcaa gaccattatc
     9541 atcgtcctcc acgatatcaa catggccagt cagtatgcag atgaaattgt cgccttcaag
     9601 gacggccagg tctttagcaa gggaagaacc gatcaaatca tgcaggctga cctgctcagt
     9661 caactttatg agattcccat cacgctagct gatatcaata acaaaaagat ctgtatctat
     9721 agctagtaac ataaaagctc aagttagaga accttcagtc tcttagtcaa taagattaag
     9781 agactcccta aatcgttatc acattttaaa aaggagaaat tatgaaaaca tcccttaaac
     9841 tttatttcac tgccctagtg gccagcttct tgctcctact tggtgcatgt agtacaaact
     9901 caagcactag tcagacagag accagtagct ctgctccaac agaggtaacc attaaaagtt
     9961 cactggacga ggtcaaactt tccaaagttc ctgaaaagat tgtgaccttt gacctcggcg
    10021 ctgcggatac tattcgcgct ttaggatttg aaaaaaatat cgtcggaatg cctacaaaaa
    10081 ctgttccgac ttatctaaaa gacctagtgg gaactgtcaa aaatgttggt tctatgaaag
    10141 aacctgattt agaagctatc gccgcccttg agcctgattt gattatcgct tcaccacgta
    10201 cacaaaaatt cgtagacaaa ttcaaagaaa tcgccccaac cgttctcttc caagcaagca
    10261 aggacgacta ctggacttct accaaggcta atatcgaatc cttagcaagt gccttcggcg
    10321 aaactggtac acagaaagcc aaggaagaat tggccaagct agacaagagc atccaagaag
    10381 tcgctactaa aaatgaaagc tctgacaaaa aagcccttgc gatcctcctt aatgaaggaa
    10441 aaatggcagc ctttggtgcc aaatctcgtt tctctttctt gtaccaaacc ttgaaattca
    10501 aaccaactga tacaacattt gaagactcac gccacggaca agaagtcagc tttgaaagtg
    10561 tcaaagaaat caaccctgac atcctctttg tcatcaaccg tacccttgcc atcggtgggg
    10621 acaactctag caacgacggt gtcctagaaa atgcccttat cgctgaaaca cctgctgcta
    10681 aaaatggtaa gattatccaa ctaacaccag acctctggta tctaagcgga ggcggacttg
    10741 aatcaacaaa actcatgatt gaagacatac aaaaagcttt gaaataagcc tcttcaaact
    10801 caatttaata ctcaatgaaa atcaaagagc aaactagaaa actagccgca ggttgctcaa
    10861 aacactgttt tgaggttgca gatgaaagct gacgcggttt gaagagattt tcgaagagta
    10921 taaaattttg acattctaaa acgcatccta tcaagttcac tcaaacctga taggatgcgt
    10981 ttttatcatt ttgaaatcta tttaccccac ctcattcccc ttcttgattt cgtttaaggg
    11041 aaaagcggtc tggaacgggg tccttacctg ttttcgacca gggatgacaa cgtaaaatcc
    11101 gagacaagcc catcaatacc cccttaaaac catgtttttc aatagcctga atcatgtagt
    11161 tggaacaagt cagctcaaag cgacaagagg gtggaaagac tggtgagata aaacgttggt
    11221 aaaagcgcac aggcgctatt aaaattcgtt tcattatttc ttagttacag ccatggtgtg
    11281 tagttggctg atttcttttt tattaagacg acgggattct cctggacgga gtcctgtcaa
    11341 gtctaggtgt ccaaaacgag tccgagacaa cttatctact tggagaccaa cagcttcaaa
    11401 catcttttta acctgatggt tacgcccttc atggatgatc aactgcacca cagagcgatt
    11461 tttgactggg tccactttga gaatttcata aacagctggc ttggttttct taccatcaat
    11521 ctcaagacca cgggtcaagg ggcggagatt gtccttattg gccacacctt taacacgcgc
    11581 gacataaacc ttgtcaatct cattacgagg gtgaatcatc tcgtctgtaa agtccccatc
    11641 attggtcaaa atcaagactc ctgatgtatc ccagtccaaa cgacccacag ggtaaatacg
    11701 ctctttgaca ttgggcaaga ggtcgacaac cgtcttgcga cccttatcat ctgtcacact
    11761 ggaaatcaca ccgcgtggtt tgttaagcag atagtagacc ttttcttcgt tgtagatagg
    11821 ttgaccttca acttcgacct tgtcgcctga cttgatagtg gttgctagtt cacgcaccac
    11881 ttggccgtta accgtcacca agccttgctt aatcagctct tctgcttttc tcctactggc
    11941 cacacctgcg tgggcaatat acttattgat tctcatcttc ttctatcctt tcaccaaata
    12001 attggctttc ttgggcttga atctcaagct catcaatcac tggtaattct tctaaatggt
    12061 ttatccccat gtaatctagg aaataatccg tagtcacata gaggttgggg cgccccaata
    12121 cttccttttt cccgtcttcc tttatcaggt caaaagcctg caactttgcc aaggctccac
    12181 tcgagttaac tccacggatg gcatcaattt ctatccgcgt aatcggctgt ttgtaggcaa
    12241 taatggacaa ggtctcaagg gcagcccgag acaagctctg gttgataggc gccttagagt
    12301 attccttcaa aatctctgca aattgaggct tggtcaccaa tctataagca ccacttgtct
    12361 caatcaaagc caaactggaa tctgggtcct tttcatactt ctgggctaat tttcctaaac
    12421 tttgctggat gcctgtcggt ggtagagaga ggagttcagc taactggcgg acccgaatcc
    12481 catcttcacc cgctacaaac aagagcgctt ctatttttgc taaagtactc atctttcctc
    12541 tctatcaagt ctagctttga ggcacttgac tttcttcctt cttttccatg agatagatat
    12601 ctccaaaact ctcctcttgc acgaggatca gctcctgggt tttgattaac tctagggttg
    12661 ccaaaaagag ggtgatgacc tcttggacat tctgggcttc cttgaacaaa tcctgcaagc
    12721 gcaattgatc tcgtccaatc aaggactctt tcacgataat catcatgtcc tcaatcttat
    12781 actcatcccg caagatcgtc gtgtgatttt gtgcaaactc ctcttttttc ttggctagga
    12841 tatttgaaaa agccaaaaag aggtcaatgg tcgtcttgtc atgcacaagc tccgcatctt
    12901 cgtaaatcaa ctctgtcggc gctttggaat aatactgggc ccgttcttgg tgcttggctt
    12961 ccaagtgctc acccaagagc ttgaacttgc gatattcttc gatttgagag aggaggtcct
    13021 gctccaggtc atcccccaag tctgtcactt ctgctacctt cggaaggagt ttacgactct
    13081 taatcagcat gagctgacta gccatgacca tgtactcacc cgtcacttcc agacgcatgg
    13141 cctgcagggt tgagacatag gctagatact gttcgatgac ttccgtaatg ggcacatcgt
    13201 agatatccat ctggtactta gaaaccagat gcaagagtaa gtccaggggt ccttcaaaat
    13261 cttttaattt aatatccatt atctatattt ttctaaggtc aggactgttt ttaatcctaa
    13321 tttttttgca atttcgtaca aatcgacctt gttttctatt tgtcttagaa taaactgttc
    13381 acgtaagact tgagctgata aggatggaaa acctttctcc ttgacaaaag attctaactg
    13441 acgaaaggcc cactgacgag aatagggttt ccctcctctt tcaaaaagat aggtctgccc
    13501 catcaagggt tccaattctg aaagcaaggc cgtgggaatg gtgacaatcc tctgttggga
    13561 agccttgctg attcgcagca cctgaaaatc cagattgatg tccgcaacct tgatggctaa
    13621 aatctcactg ggcaagagcc ccatttctag gattaagagc gctagcaagc ggccctctgg
    13681 atggtcgctt tcctgccaaa aagagtctag gtatagaatc tctggctttt ccgtcttctt
    13741 ttcagcttgt ttggctaatt ccaagcggta aaagctgtcc acctctcctt tttgatagag
    13801 aaagtataga aattggttac aggccgaaat ctttcgcttc tgggcgctga tttttagatt
    13861 ggctagctgg gcttggtaaa tcttgagact ggtctcagaa atccgctcac ctaccatgtc
    13921 taaaaattgc tccaaatcat acttatagga ctgcttggaa ttgacagaca agccctgctt
    13981 ttcctctaaa aaggctgaaa ttctgtctct cattggcatc gaatctcata ttccttacta
    14041 aaatcatgca agagggcatt aacggccttg aggatggact tgcgcgtaat aatcccttgg
    14101 aaaataccct ctgtatccac aaccggtaag aaggactcat ctactagctt gtgcaagacc
    14161 tccgtaatgg tgaaatcagg cgaaacaacc gctacgtccg tttttgtcat atgaacgata
    14221 tccgtatccg ccatgatttc ttggctcaag tcatgctcca tctgataagc cataatatct
    14281 ctgagtccaa tcgtcccaac aaactgtttt tcatctgtca caacgggaac acgggtatag
    14341 gtcatctgac taagcaagag ggtcgcatga tccgcattgt gggtatcaat caacacagct
    14401 agatttttag caggggtcaa aaaagtttcc tcctgcccca acaagaaagt ctcaaactcc
    14461 ttggcaatca tcggctaaac tccttggaca aacctggata cacctcgtga tctcgtgtca
    14521 aaaagtccac tttgaagtaa ctatcatcaa tctccacacg agcatagaga cattctctga
    14581 tggtacctcg tggttggctg atagaacctg gatttagaaa gaggatcttg ccttccatcc
    14641 aagcacttgg cacatgcaag tgaccataga ggcagatagc ggcctcttcc tcctgagccc
    14701 agtagtccaa cttttgaaag ttgaaattga tgtcaaacaa gtgaccatga gtttggataa
    14761 tcttggtcga accaagctca gtcaccagac gttctgggta gccggcgtag aagtccatgt
    14821 tccctttaac aacgcggatg ccctcccaaa gtggagaatc cggacgtagt tcagaatcgc
    14881 cgttatgaaa aacggcatcg actttgccca catagcgatc acggacttct tccacaatca
    14941 agctatcgcc atgggaatcg ctcattacaa tgatggtttg ctttgccatg atggaaatac
    15001 ctccaaaagt ttcttaacgg ctaaggcacg gtgagattga ctattttttt cttccagggt
    15061 taattcagct gatgactcac ctgtctctcc tacaaggaag aggggatcat agccaaagcc
    15121 attttcaccc ttaggttcaa agttaatata acctgaccag tctgcttcaa caactaaact
    15181 ttccttattt gggctggcta cgactagggt tgtgtggaac tgagccgagc ggtccttgag
    15241 ttcaaagacc atggccaatt cgtgcaagag tttggcatta ttttcacggt cagttgctcc
    15301 cacacctgcg aaacgagctg accagacgcc tggtaagcca ccaaggacat cgactttgag
    15361 accagaatca tctgccaaaa ccatcttacc cgttaattga gaaatggttt ctgccttaag
    15421 gcgggcattt tcttcaaagg tcatacctgt ttctgctact tcaggcaggt cagggtagtc
    15481 attaagattt tccacatcgt agcctaactt atcaaagata gctcggaatt ccttggtttt
    15541 gccttcgtta cgagtcgcaa tcaacaaggt ttctctgacc ttgcttgtct caaagaaatc
    15601 atgaacattg accccttctt taggcaattc tacatacaag agttgcccat tttcaaccaa
    15661 gagcagggcc ccatgacgtt gaataacttc caagtttcgt cccatttctt gattaagcat
    15721 atctaccaca aaggagaaca aacggtaggt agaaccatag cgtaaaacag taactgaaag
    15781 cgggaaacca tactcttcat ctccaaatat tttggagaat tcaaacagag gaaaatctgt
    15841 ctgatagtcg ctcaaactgt taacgccacc aaaaatacta taagacccaa cataccagtc
    15901 ctggtcatcc ttatattcat aaattttatt tgtcataatt ctacatgctc cacatgaatc
    15961 tctttttcca gccattcttc accaatttgt gcaaaacttt ggctactggc tgttgtgtaa
    16021 aaacggtgat ggagtggtcc agcatcgcga ccacgattga tttcaaaata attgagtaag
    16081 actgagatat cccgtacgca ctctgcccca ctatcgatga gctgaacctt tggccccatc
    16141 acattttgga taatagggcg aaggagtgga taatgagtac agcccaaaat caggctatcc
    16201 acctttccaa ccaagggacg cagggtttca tagaccacct tcttggtaac actggttgac
    16261 agggcacctg actcaaccaa gggagcaaac ttgggacagg ccaagctctc cacctgtaag
    16321 tcgggatcca gatcatggat tttctgacgg tatatgtctg attgtaccgt catgggcgtt
    16381 ccaatcactc cgattttccc accttgactg gacttgatgg ctgccgaagc tcctggcaaa
    16441 attacaccca agacaggaat atctagttga gccttgattt cttcccagac gaccgcagtc
    16501 gcagtgttac aagcaatgac aatcattttg acatccttgg tcaagagaaa gttgaccagc
    16561 tgccaagtat attcacgaat ttgctcagca ggacgggggc catagggcgc ccgcgccgaa
    16621 tctccaatat agacgatttc ttcatgggga agctggcgca tgagctcgcg cacaacggtc
    16681 aagcccccga cacccgaatc caaaaaacca attggtcgat tatccataca gtcttctttc
    16741 tagtcttttt tctgattgat cgttcattat gattccttgt actgaacgaa ctgaccgaca
    16801 gcttgataga atgtcaacta cctctctctt aatcataatc aaatatcaat agaatgcaag
    16861 gaaaaagtct catccctaaa ccataaccaa catagtgaga agtctggaac tttcatccca
    16921 gacttttcct tatttatttt ttctttttat tgttagcaag ggctgccttt tgttggcgga
    16981 tgatttggtg gtaaacttgt tgtaccttag cttcgcttgg tttttgacca tttgcactca
    17041 aaagagtacg aactgcttca gcattcaaac gtgggttgtc agcaaattct ttttcgattt
    17101 gcttacgaac caagtacatt cctccaagag ctcctcctag aaaagctagc acaatcaata
    17161 caattgctaa aagtaaatcc atcatttttc tcctgtttct ttttgagtcc ctttcattat
    17221 accacaaact agccaccctg accagtttgt tctacacttt caaggatgga atagacagca
    17281 aaaagaaccc tgcttttctg aaaaagaggt ctccttgcta agtttaattt acataaatag
    17341 ccagtgtttg atagggtttt agtagaattt tctcagacac ttctgcatct tcatagtttg
    17401 aaatcaaaat ctgtccattt tggtagactg ctggcaagtc gatttccact tctttagcat
    17461 aaaagttatt gagcactagt aacttttgat cctcaaactg gcgttcaaaa gcgtagactt
    17521 gtttgctatc ttcaaaggct ggtttgtaac ttccttctga aatgattggc atttccttac
    17581 gcagtcgaat caagtcttga tagaaggtaa aaatcggacc ctggatttca ttttctacat
    17641 tgatgtattt ataggattta ccagctttca accaaggagt gcctgttgaa aatcctgcat
    17701 tttccgaagc atcccactgc atgggaatgc gtgaattatc acgcgactta gcttgaataa
    17761 tctggaaggc ttcttgctga ctctttcctt cttctaagag catctgatag gcattaagcg
    17821 attcgacatc cacataatca gccatagaat catagtctgg gtcaatcatc ccgatttcct
    17881 cacccatgta gatataaggt gtcccacgtg acaggtgaat gctggctgct agcatggtgg
    17941 ctccttcctt gcggaagttt tgaatatcga caaaacggtt caaggcacgt ggttgatcgt
    18001 gattgttcca aaagagggca ctccaaccgt ctttatcact catttcctta ccccaactat
    18061 ggtaaagact cttcaactct tcaaaatcaa agggagccaa ggtccacttt tgtccatcct
    18121 tatagtccac cttgaggtga tgaaaattaa aggtcatgga taattcctga cgatcaggcg
    18181 acgaatagag gacacagttt tccatggtgg tagaagacat ttccccaact gtcataaagc
    18241 tatcgtcaga tccaaaagtg gcttggttca tcatacgcaa atagttatga acgatgggtt
    18301 tgtctgtata agctggcttc ccttcatttt caggacagtc cactgaaacc tcgtccttac
    18361 caatcaaatt gatcacatca aatcgaaaac ctttgacacc cttgtcgcgc cagaaattaa
    18421 caaccttgaa aagctcctta cggacattgg gattgcgcca gttaaggtca gcctgggtct
    18481 catcaaatag gtgaagatag tatttcccag tatccccgaa aggcgcccat gcagaaccac
    18541 caaacttaga ctgccaatct gttggttggt cttggatgaa gaaaaagtct tgataatact
    18601 tatcaccagc tagggctttc tgaaaccatt catgctctgt cgaacaatga ttaagtacca
    18661 tgtccagcat aaagtcaatc ttgtgctctt taccgataca caccatttcc tcaaaatcag
    18721 ccatatcacc aaaaagagga tccactgcca tataatctga aatatcgtaa ccattatccc
    18781 gttgaggact tggatagaat ggattgagcc agaccatatc cacacctagt ttggctagat
    18841 agggaatttt tccgataatc ccacggaaat ccccaatacc gttttcagtg gtgtctttgt
    18901 aagattttgg atagatttga tagactactt ttcctttatc aagtgtcatc tgtttctcct
    18961 tttctgataa aagggaggaa gcagtcttcc gtccctattt gtgctatttc aattatactc
    19021 aatgaaaatc aaagaacaaa ctaggaagct agccacaggt tgctcaaaac actattttga
    19081 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattag attcgtgtag
    19141 cgaccatgag agatgctcca gcttggatcg ttgtcggata agttccggga atagtcgctg
    19201 tataagcatc ttggttggtg atgataacag gagtttctgt caccagacct gcagccttaa
    19261 tgacatccat atcaaaacga atcagttgct gaccaactgt aacgtgatct ccttggacta
    19321 caagactttc aaaacctttg ccatcaagac ctactgtatc cataccgatg tggatgagca
    19381 attcaactcc ctcgtcagag acaatgccga tggcatgctt ggtagggaaa agaaccgtca
    19441 ctgtcccatt aactggagag gtcaactcac cttggcttgg ttcaatgact agaccttgcc
    19501 ccatgacacc tgatgcaaaa ataggatccg tcgcttgact caattctttc acttggccag
    19561 ttagtgggct gataatttct accgaagtaa gttctactgg ttcatggttc acaaattctg
    19621 cttcttcttg agcaacgaat tctgcctgca agttcgtatc gccctctgtt tttgtaaaga
    19681 gaccagcctt gcggaagaag aaagtcaaga gcattggaac aacaatcgca actagcatag
    19741 ttcctgcaaa tggcagcatg tattgaggtt gaatagagag aatacctggc aaaccaccga
    19801 taccaataga agccgcagtt acattaaaag taacggataa catgcctgca agggctgaac
    19861 cagtcatccc agcaacaaat ggataaatat attttacgtt aaccccaaaa agagctggtt
    19921 ctgtaacacc gagataggct gaaatggttg caggaagtga aacctgagcc tcacgctcat
    19981 catggcgatg catgaaataa taggcaaaca cggctgagcc ttgagcaata ttagaaagag
    20041 caatcattgg ccatagggca gtgccaccag catccgcaat caattgtgta tcaatggcat
    20101 tggtcatatg gtgcagacct gtgatgacaa atggagcgta gagggcacca aaaattgcac
    20161 cgaagagcca tttaactgga ccagttaaac ctgccaagac aactgatgaa agcccttgtc
    20221 caattgtcca accgattggt cccaaaacag tatgagccaa aatcaaggct ggaatcaatg
    20281 acaagaaagg tacaaaaatc atagaaatga cttctgggat atgcttgcgc cagaagattt
    20341 caagataaga cagactcaaa cctgcaagca aggctgggat aacttgggct tggtaaccga
    20401 tacgattaac agtaaaatag ccaaaattcc aaacccagtt tgccgcgata tcagctgctg
    20461 gcgttgaagc aaccgcatag gcattgagca actgaggcga taccaaacag attccgagaa
    20521 caattcccaa aatttggctg gttcccatct tacgagaaac agaccaagta atccctactg
    20581 gtaagaactg gaagatagct tcaccaggca accagaggaa gtgattgaca cctgcccaaa
    20641 actgagagga ttctgtgatg gtcttgccat ccaacatcga ccaatggaca ccttccaaga
    20701 cattacggaa accgaggatc aatcctccga ctatcaaggc tggaataatc ggagtaaaaa
    20761 tctccgccag agtggtcata acacgttgga ccacgttttg attactctta gctgcagact
    20821 tggctgcttc tttggaaaca ccctcaatac ctgaaacggc tgtaaaatca ttataaaaga
    20881 tgggcacgtc atttccaatg attacctgaa attgacctgc atttgtaaaa gttcctttaa
    20941 cagctggaat tgactcgata gctttaacat tagccttctt atcatctcct aaaacaaagc
    21001 gcatccgtgt cgcacagtga gttacggcag tcacattttc tttgcctcca attgcctgaa
    21061 gcagatcttt ggcttcttgt tcaaattttc ccatttgatt ctccttatac ttgtcaaagc
    21121 aagtttgatt tgataagtat attgtaaacg ataccaaact tgtctgcaac ttgtttggta
    21181 taaaaagggt gtttttttgt aaattttcta gcacttgtat ggtaaaatag atacaggtgt
    21241 tcattaaact agactaaaaa cctatttaag caggcaaaat gaagaaatac caacaattat
    21301 ttaagcaaat ccaagaaacc attcaaaacg agacttacgc tgtcggagat ttccttccta
    21361 gcgagcacga ccttatggag caatatcaag tgagtcgtga taccgtccga aaggccctgt
    21421 ctctcctcca agaggaagga ttgatcaaaa agataagagg gcaaggttct caagtcgtca
    21481 aagaagaaac cgtcaatttc cctgtatcca acctaaccag ctaccaagaa ctagttaaag
    21541 aacttggact gcgctctaaa accaacgtgg tcagtctgga caagattatt attgataaaa
    21601 aatcctcact gataaccggt ttcccagagt ttcggatggt ttggaaggtg gtccgccagc
    21661 gtgtggtgga tgatctggta tccgttctgg atacagacta tctggatatg gaactaattc
    21721 caaatctcac tcgccaaatt gctgagcagt ctatctattc ttatatagaa aatggcctca
    21781 aactccttat tgattatgct cagaaggaaa tcaccattga ccactcaagc gaccgagaca
    21841 agattctcat ggacattggc aaagaccctt atgtcgtttc gattaaatca aaagtctatc
    21901 tccaagacgg acgccaattt cagtttaccg aaagtcgcca taagttagaa aaatttagat
    21961 ttgtagattt tgcaaaacgc aagaaataaa agactgagac accagatctc agcctttttc
    22021 tttatcccaa aactaattca tcactgacca gactttggcc actatttttc tggaagagat
    22081 gcataaggtc ttcaactgtc agatgctttt tctcttctcc cttgacatcc accactatct
    22141 tgccttgata gagcataatg agacgattgc cgtactcaat cgcatgattc atatcatggg
    22201 taatcatcaa agtcgtccac tgatggtgct ccacaatctt ttgcgtcaag tccatcacca
    22261 tttgactggt tttcgggtca agtgccgcag tatgttcatc caaaagtaaa agtttgggtt
    22321 tcaccagagc tgccatgact agggtcaaag cctgtctttg tcctcctgag agatattgag
    22381 tatctacttt taagcggttt tcaagaccaa tattcaactc cttcaaggcc tcttggaact
    22441 ggattctatc cttctccttc acaccccaac caagccctct cttttgccca cgtctcaagg
    22501 caatagccat attctcctca atcgtcaaac gagaagctgt tcccatctta ggatattgaa
    22561 aaacacgggc aatatccttg gctctctttc tgacactcag atttttaatg gatttccctg
    22621 ccagtagaag gtccccttcg tccaccgata gattgccagc caagatattc atcaaagtgg
    22681 attttcctgc tccatttcca ccaatcacat agataaaatc tccctcttca acctctaaat
    22741 ctaatccttt gaggacatgg ttctcattga ccgtccctgc ttcaaatgtc ttgtgaatat
    22801 tttcaagtgt taacaaactt gccataactt tctcctccta ttcatttctc aatttcagac
    22861 cacgaatctt taatctcttt tgcaattctg gtgcaaataa aaccaaagcg agcaagattg
    22921 cattaaagag acgtaccaag ttttgatcta gatttggaat ttcatagata tttaaaataa
    22981 tcaaacggta aacaatagca ccgattccga tggataataa gcggcctcca atggtcaagt
    23041 cgtgtatcaa gacttccgag ctcaaaccaa caacaatggt tcctgtccca gaagtcacat
    23101 ctgaaaatcc atcattttgg gcaaacaagg aaccacatag ggcaatcaaa ccgtttgaaa
    23161 tcatgtaacc aacaatcttc atggtgtcta cattgactcc attggcctca cttatcggga
    23221 tattatcccc agtcgaacgc aagaccaaac caatctctgt tttcatcaaa agggtcaaga
    23281 ccaaacaagt aagagacaga ctaaactaag tgagaaaaca gctccttcat ttgtcagacc
    23341 caagctcgcc aactgtttaa agacggttgc agaatctccc aaggaaagat tgggtacact
    23401 gcccataatt ttaatattga ttgaatagag ccctgtcaag gtcacaatcc ctgtcaagag
    23461 agctgggatt ttcatcttgg tgtggagcat tcctgataca agacctgcta ccatacctgc
    23521 cagcaaagca agtaaagtcg caagccaagg atttgcccct gcctgtatct gtgatacaac
    23581 gactgctgcc cccagaggaa aggctccctc agcagttata tccgcaatat ccaaaatacg
    23641 gaaagtcaag tagaccccaa tcgccacaat cgaccacaac aaaccttctg ataaactaga
    23701 taacacaaaa ttcatcttaa tcctccttat tccttgcctt ctaacttact aatatcaatt
    23761 cccaatgcat ctgccatttc ttgattggta tgcaattcca gtttttcagg caactcaact
    23821 gctatatttt ctggtttctc accttttaaa acacgaatca gcatgcgagc tgtctgtctt
    23881 cccaattctt cataattggt tccgtagtta tacaagtcac caacagcaat catttctgtt
    23941 gaaccaccga atactggaac cttgtgttta atagaaacct gcttaactgt ttccatggtt
    24001 gacgaaatga tattatcagt tgggacaaaa accatatcca cctctgccat caaactctct
    24061 gctgccgcct tgacgttatt actgtccaag attgtttttt caacaacggt aaagcctttt
    24121 tctttcagaa gtcgcttagc ttcatcattt taaacaaccg aattgggctc gctctgagta
    24181 tagaggattc caatcgtttt agcctttggc aacactttct ttatcaaatt gatttgggtt
    24241 gaaatggcat ctgatgactg atcgcttgtc ccagttacat tgcccccagg atgttctctt
    24301 gactcaacca acttggcact gactgggtct gttacagctg aaaagataac tggtggcgtt
    24361 tgcgtcgtat tggccaagct ctgagcagaa ggccttgcga tggctagaac gacatcgctg
    24421 gattctgcta gttgctggga aatcgttttt agatttcttt gttctccctg tgcattttgc
    24481 aaatcaatct caatattttc cccctcaaca tagccttgtt tggccagctc atccacaaat
    24541 ccttctctag tagcgtctaa ggactggtgg gtaataaact gcgaaatacc gatacgaaag
    24601 acatctcttt tcttatctgc cttcaactga tgcaaactga tcagagaagt caagaggatc
    24661 cccactacca agagggggct agtgattttc gaacaacttt cataatgaaa ctccttctca
    24721 gaaaagataa aacaaaaaac cgcctagata ctatctaaac gggtacttga aataacctaa
    24781 caagttacaa cttagctagt ccatttagat attcatctat atggaccaca atcaaaaatc
    24841 ttagccacat agatacaaac aaattgcttg aactgtttgc atccatggtg acatgtctac
    24901 aaacactatc taaagtagct aaagtaaaag ttttgattca tagttacggc ttgtctctta
    24961 ttcatttctt tttctgcttt cttttttgat ccttcctatc ctaccacctt tttcatcacc
    25021 tgtcaataat atttcaaaat tttttaaaat ttttcgaaaa ttctttcagg aagctttcaa
    25081 agtttttcaa atcagtccaa caaaaaaagt tttataattc ccataaaaat tgacatggaa
    25141 attataaaac cattattagt ttagtccttt ttgataacgt gccaattcgg cttggttcgc
    25201 ccaaacatag tgacctggac ggatttctac catagatggc ttatcagtct catagtcgtg
    25261 ttgacttggg tcgtaaacct tcaagacctt cttacgttcc aagattggat ctgggattgg
    25321 tactgctgaa agcaaggctt gagtatatgg gtgaattgga ttgttaaaca attcttctgt
    25381 ttctgcaacc tctacaataa cacccttgta aataactgcg atacgatctg aaataaagcg
    25441 aacaaccgac aagtcatgag cgatgaagag ataggtcaag ccgagctctt tttggaattt
    25501 tttgagcaag ttcaagactt gggcacgtac agaaacgtcc aaggctgaaa ttggctcatc
    25561 tgcaataaca aagtctggtt gcatgaccaa ggcacgggca ataccgatac gttgacgttg
    25621 accgcctgag aattcatgag ggtaacgagt caagtgctca gcaagaagac ctacttcacg
    25681 gataatactt tgaactttct ctttacgttc ttcttcatcc ttaaataaac ggtgattgta
    25741 aagaccttca gaaataatat aatcaacagt cgcacgttca ttcaaacttg cggcagggtc
    25801 ttggaaaatc atctggattc gacgaatcaa ttccgcagct tgttcacgcg atttcttacc
    25861 attaatcttt tgaccatcaa aaatgatatc tccattactt gtatcattta gaccgatgat
    25921 agcacgacca atagttgttt tcccactacc ggactcacct acaagcgaga aagtttctcc
    25981 cttgttgata aagaagttag catttttaac cgcgacaaac ttcttacttc cttcaccgaa
    26041 ggaaatttct aaatctttga tttctactaa tttttcagac atttccttcc tcctagtcag
    26101 ccagatgggc aaatcccatt ttttcacgga tcttatcatg gagatttgca atcacagctg
    26161 gtttttctac ttttggagca tcctcatgaa gaagccaagt tttagcccaa tgtgtctctg
    26221 atactgagaa ttgaggagct ttttgttcga agtcaatctg cattgcgtag tcagaacgca
    26281 aggcaaaagc atcccctttc aggtcagtat aaagtgacgg aggtgttcct gggattgagt
    26341 aaagatcccc tttatcatca gcaagctgag gcaagctaga caagagactc catgtatatg
    26401 gatggcgagg gtcatagaag acttcctcaa ccgttccata ctcaacgatt tctcctgcat
    26461 acataaccgc taccttatcc gcaatacttg ccaccacacc aaggtcgtgg gtaataaaga
    26521 ttgttgtgaa atgatactcg ttttgtaaag attttagcaa atcaataatc tgagcttgaa
    26581 tagttacatc caaggcagtt gttggctcat cacagatcaa gacatcaggt cggcaggcaa
    26641 gggcaatcgc aataacgata cgttgacgca ttcctccaga atattggaat gggtattcat
    26701 taaaacgtct atctgcgtct ggaatgccaa ccttattcat gtagtcaatg gccaattctt
    26761 tcgcttcttt agctgttttt ccttggtgtt ttacaataac ttctgtaatc tgactaccaa
    26821 ttgttttaat ggggtccaaa ctagtcattg ggtcctggaa gatagtcgca atcttagcac
    26881 cacgaatttg ttcccaatcc ttgtgagaag ataaagctgt caagtcctga ccacggtagt
    26941 caatactacc ttgggcaatg cgaccatttt cttcgagcat acctgtgaag gtctttgtca
    27001 aaacagattt acctgatcct gactcaccta ccaaggctaa tacttctcct tcgactagtt
    27061 caagggaaac gccgcgaatg gctgtcaata ctttgtcacg aacgtcaaat tccacgacaa
    27121 tatcgcgagc agtcaaaatt acattttttt cttttgtcat ttctactcct atctatgtgt
    27181 acgtggatca ctagcatccg ctaagttttg accaactacg aaaagggaca aggataccaa
    27241 gacaagggtt gtcaatggaa tccagaacaa gtaagcattg gttgttacgt tttgtgaata
    27301 atccgaaatc aaacgaccca aacttggcac tgtaatcggt aatccaagac cgaagaaaga
    27361 caagaaggct tcgtatgaga taaagcttgg aagcatttga gtcatggttg tcacaataac
    27421 agataccaat tgaggcatga tatttttggc aacaatcttc aaggttggtg ttcccaaagt
    27481 acgtgacgcc aagttgtatt ccaagtcacg atagcgcaag atttgcacac ggatcatgaa
    27541 ggcaatacca atccatgttg ttacgctcat ggcaaaaatc agattccaga atccagctcc
    27601 gattgagtaa gtcaagacaa taacaatcaa aagaggtggg atgtttgaga tgacgttgta
    27661 aacttccatc atgacacggt caactgattt tgaaataccc caaataccac cgacaaaaac
    27721 accgataacc aagttaatca ctgtcgcaat cacagaaatg aggatggagt tacgagctcc
    27781 gaaccagaca ccgtcaaaga gcgatttacc gttactgtca gtaccgaacc aatgctccgc
    27841 atttggcttg atataacgaa cactaaagtc gtttaccttg ctgacatcat tgaaatcaaa
    27901 cttagaaaac attgggtaga tgaaacttat caaaatgatg gctaccaaga ttcccaacat
    27961 gactacagtt gattttttct tcataaattg tttaaacact gatttccagt aagaatatgc
    28021 tggcgcatca atagtttcag aggcaaaatc gtcacgtttt acaaactgaa atttttcttt
    28081 atcgattgta gacattattt gcctcctttc tcagtcaatt taatacgtgg gtcaataata
    28141 gtcatccaaa tatctcccaa aagacgtgag aagatagaaa tacatgtaaa gatgaagaca
    28201 agaccaacga ccatagagtt attagatgct tttacagagt caatcaacat tttacccata
    28261 cctgggaagg cgaagactgt ttcagtaagg gttgcaccac cgataacccc aataatggca
    28321 ccaggaattc ctgaaaccag cggaaccatg gcatttttaa agatgtgttt gtttgaaatt
    28381 tctttttcag acaaaccttt tgcacgagcg aaacgaacaa agtcttgaga ttgcaagtca
    28441 atcatgtaac gacgaatcca aatggctgta ccaggagcac ccaacaaacc aaggatgact
    28501 gctggtaaaa cgtaagaacg ccaatctcca gctcccaaga tagggaatga atctggaagg
    28561 gcaatagatg atccaatcaa tcgaacgatg taaaccaagg caatcgttgg aagagcaagc
    28621 aagaaggtca aagcccctgt tgagaggcta tcaatccaag tgttcttgaa acgagccatg
    28681 gctgaaccaa gtggcacggc aagagcatag gcaagaacca aaccaatcaa accagtaata
    28741 gcagagctga caatcataga tggatattgg taattacttt cagtcgctgt ataaggatca
    28801 tctttcccat agctagctac ttcacgagag tcagcctgac taggtgactt gtaggttctt
    28861 gagtaaatat ttacagaaga cgttttctta cctgttggga actgaacttg ggcagttttg
    28921 gtttgtcctt gaccttgagt aataacctga agaactggtg tattagcata ggttgggtaa
    28981 gagtcaccta aattcaagtt cacaaagttt tgatgaacaa atgggaactg actgttaaag
    29041 tacaagagat atttatgttt agttcctgaa ccgaccaatg accatccgat agctggatca
    29101 ttttcaaaac gaaggtagcg tttcaagtct ggattttcag ggtcttggat tttatttgta
    29161 tggtcaatgt caatcaagtt agcatagaag tgaaaaacac gttcaaaaat tggaatttca
    29221 cgagtagcat agaattgacc actttcagta aattctccca aagtccaacc atgacctaat
    29281 tgattgatgt acttttcata aatagcttta ttggtcgcat ttgcttctac tgttacagaa
    29341 gaatccatgc tacttgcctt ttcttgcaac tctttagtat cgtaatactc aatgtagccc
    29401 atacgctcaa acacagtatt ttcatagtta tcacgtttat cagccgttgt cgcaatttta
    29461 ttatagttag gatcctgctt gaaaatcaat tttcgaggaa ccaaggtata gataatcgtg
    29521 taggtcaaag tcgttactaa gaaaatcgaa accaatgacc gcaaaacacg cataaaaata
    29581 tattttttca tattatttcc tttaaaaatc ccaaaagaac cttctcctca tggagagaaa
    29641 gttctattag aaattattta cttcacatga cttgccaatt ctttttgagc tttctcattt
    29701 gattcagctt tttctttcaa ccatttttca cgagcttttt catactcttc cttagtcacc
    29761 actttatctt gtaatttcaa atatttgaag taaacatctg accccttaga gcctgtttgc
    29821 gcagaagctc cagtaaatgg aacaattcgt gaaagcactg gtgctgcacc agaagaagcc
    29881 atagcaggaa taaagagtga actatctgtc aaccatgctt gagccgctgc atatttttca
    29941 taacggacat tcaagtcgct tgtctctctg gcagcttcat caactaattt atcgtattct
    30001 ttcaaaccaa cttgaactac tgaagggcta tttggattat caaatcctaa atatgttttt
    30061 gtagtttcac tgctagttgt ttttaaaata tccaggtaag tagatgggtc ttgatagtct
    30121 ggcccccatg aaactcctcc tgatacatcc caatcctcag atgaagcatt ggcagcatag
    30181 taagtaatat taaggaattc atcacttgtc atttgttgaa tatcaacaac gacattttca
    30241 acaccaagaa ctgtttctac agattgttta aaggactgaa tacgagatat gtagtttttt
    30301 gatgcttggt ctactggaac gtccagatga ataggaaact gaacgccgtc tgcttctaaa
    30361 gctttcttag ctttcgcaaa ctctgccttg gccttgtcag cattgaataa accatcctgc
    30421 ccatcagcta aattcacacc tttccactca tcaccataag caggaagttg agcagcgact
    30481 aaatcaccaa aggtcttctc accagctgaa acaaagtctg gttttacaaa taaattacga
    30541 actgctaaag ctgctccatc tttaccattg atttgagctg agtaagctga gcgatcaaga
    30601 gcaaaattca aggcttgacg gaaatctttg ttaagcaatg ccttcttagt agctactttc
    30661 tctgaatctg tagttttaga agtatagttg taactttggc gatcaatatt cacacccaga
    30721 ccagcaatcc cagagcctga ttgtgtgtaa tagatattgt ccttgtattc ttctgcaacc
    30781 ttagaatagt tggagctggt agggtaaaga cgggcataac tataagctcc actagtgaag
    30841 ttacgctcta gcgactcctg atctgatcca tcatagtaag ctagattgat agtatctagg
    30901 tggacatttt ctttatccca atattgctca ttttttacaa actctacaga agattttgca
    30961 gtcaaccctt tcaacaagaa tggaccatta taaagcaagg atgtcggatc tgttggttta
    31021 gcaaaatcgc ttccttttga tgtttcgaat tcttcattca gaggccagaa aatagaatag
    31081 gtcaacttag agttccagaa cggttcaggc tggttcaaag tgtattgtaa cgtataatca
    31141 tcaaccgcct tgacaccaac tgttgaaaaa tctgttgaag ttcctgatag ataatctgcc
    31201 aagcctttaa ccgaattttc agctaaatac atagcttctg attttttatc tgctgcgtgt
    31261 tttaaaccgt tcacgaaatc tttagccgtc acctctgcat attcttctcc atcagaggta
    31321 aaccatttaa cccctttacg aatcttataa gtgtaggtca aaccatcctt agagacttcc
    31381 caatcctctg caactgcagg agcaagatta ccgtaattat cgttagtgaa taaaccatca
    31441 atcccatttg aagtcactac tgttgtacta tttttacttg aaatcaggta gtccaaggtt
    31501 tctgggtctg ctgtataaac atagccataa gctttagggg ctgatgaatc agatgatttt
    31561 gaagaactgc atgctgcaag tacacctgct gctaataaaa caagacctgc tgtagcaaat
    31621 acacgatttt ttttcatttt ctactcctct gtttatgtga attatagatt gacaaccatt
    31681 atatcacatt atccattaaa aatcaaacaa attttcagaa tatttaggct tgttggcaca
    31741 aatttttcat tttttttgaa tatatgattc aaattgtcgt tcgaagtgtc aaagactaca
    31801 gtgaaaatag gaaatttgac gcagaaactt tggagtttag gaagacatac agtaaaatga
    31861 aatacggacg aaacaatgtg attttggaat tcaaattaaa ttataacaat attgtagaag
    31921 tatcattcta gtattcaaga ttcagtttac tatgtctttt cacaccaacc ttattccgaa
    31981 ttcaattact tttgtgattt acatatatag attaagacta tcttttatac tttaaaattt
    32041 ctcgctacct tatccactat atgctcctcg ctatcacgtt tctattcata gcctacgatt
    32101 tcactattgc tttctctgac aattcttatt tcctgcgtca gacttaaaac gatctatccc
    32161 cagaccattt taatccgcta cctcacgata gtcaggcttg gggagcgcta ttgtattcac
    32221 cggtagtgga tccctacaga ggacttacac ctcagatgca cgacatgccc atcgtataaa
    32281 aaaatctcct acccaaggta gaagatttca aacttataaa acttaatccg tcatgtccga
    32341 taccaacatt cgatgctcca atggaatact gcacataact agcaagaaaa taaagcctga
    32401 ctgaatccag aagagagcca agtcaaaaat tccgtgcaca gcaaccactg taaggaaaga
    32461 tagataaagg ccgataatcg gacgtttccc cgactcctga ctcatatcca tcatcaagcg
    32521 aacaggagca acagaagaca aaactaataa aatggtaccc acaattccgt aactcagaat
    32581 cgtatcaata taaagactgt gggcatgttc atgataagga gcatgtatcc gaggataaga
    32641 gtgcatatag gtcaatggcc cttcacccca aaaaggattt tgcttaaaca aggccatccc
    32701 agcatcccag atagaaatgc gttcttccat agaagagtct aaagtaccca ttcgaactcc
    32761 caaatcacta gaaaagagga aactcaaacc aatcgcgaag accccaatac taagccaaaa
    32821 ggccttccag tttttaatag tcgtaaagag atagataatt gctccagcga taatagcagg
    32881 aaaggcagtt cgattttgag taaagttcaa accaaagaga ttaacaaagc ctgcaatcac
    32941 acagaatact ttcaaccaat tcaacttggt cgttgtaaac agatagaaag caatcataat
    33001 acagaaacaa caaataattc cataataatt aggattaaag aaggtcactt ctgcccggtt
    33061 ctgatgccac acctgcatat tgggtgaaag aaaagcatag ttaaatttct tcacaatttg
    33121 gaaatgttct aaactggcaa aagcagctga caagacacta ccaaacaaga cgaactgcaa
    33181 aatcaatcga aagaatttat gggataaaat cgactgatag tgcaaaaaga aaatagtaaa
    33241 tagaaacatt cctactgaag ccacaagacc catccaattt tgtgcaagaa tggatataac
    33301 agtactatag ctaagaaaaa gaagcagcat cggatgctcc cccattttct gaagaatact
    33361 tttcatgtct cctgtaaaaa tcaaactgat aatatataaa cagagtacaa ctacaaaaag
    33421 ataaaagggt aaaaagatac ttaggataat tcccaataaa atcagctctt tactagacaa
    33481 ccccttcagc ttttcaataa agcctattga tttcaaaatg aatcctttct ctccaaatca
    33541 gctgattcag ataatagtaa gctgtcctat attgtaccac ttttttagca atttgaaaac
    33601 aaaggaaacg ttttccaaaa taaaaaccct attttatcca ccatatcaag gcttcaaaat
    33661 gttacttcaa ctccattctc aattacccga taagtctgat tttgcaaatc aatttctgct
    33721 actgctgtta cggacttatc tttattttga cgtttgatta caatgctgtg agctgttggt
    33781 gtctctatct cagtagtccc ttctagatca aaggcttctg aacggttacg gaaagaaaat
    33841 agattgagaa gggccttcac aacaggtcgt tgcacttctt ttgctatttc ctcgttgcta
    33901 tagtaatgac gattaatatt tcgaccttct ttagtttctt ctaataattt caagtcattc
    33961 ttgcctgcta atagacccac atagtaaacc tgaggaatac ctggggcaaa agcttgaatt
    34021 agacgagcga gaaaatactt gacatcatca tctccaagcg ctgaatagta ggttgaattg
    34081 atttggtaga tatctaagtt gttatactcg gcactagagt acttacgttt gacattggct
    34141 ccaaccttat agagttcatt tgaagcatag tcaatctcct catcggtcag gatatccttg
    34201 acatctacta ctccaatccc atcatgggta tctagcgtcg taaattgctt catcgggctc
    34261 atctttaacc acttagccaa acgctctgtt ctggaactgt aaagagtata aagtgtcacc
    34321 attggaagag caaaatcata aacatagtaa tcatggtctg ctattttaaa ctgaatcgaa
    34381 tagtgttcat gaatctcagg taaaagctct gtcccatact cagcagcgat atctcgaact
    34441 ttgtccaata aatcccaaat atctggttcc acaaagaaat cattagtatc caatttcttc
    34501 actgcataag caaaggcatc tagacgaatc aaatcacacc cattacttgc caagtgctga
    34561 atggtcttac ggataaattc catagttact tctttggtca catcaagatc aatctgctcc
    34621 tcaccaaagg tattccacaa atgttccact gaaccatctt caaacacaat ctcttgcttt
    34681 ggtgcacgat ccttacgctt gtaaattaaa tctacatcag actgtgtcgg acggttttct
    34741 ggccaaaact tatcccagtt taaaaagaga gctttaaatt cactggcttc atgtttttct
    34801 tgatagtcct tataatactt ggattgacga gaaatatgat taatcataaa atcaaacata
    34861 agataatatt tctcacctaa atgcttaaca tcctcccaat caccaaaagc tgagtccact
    34921 tcgtcgtagt caactggcgc aaatccacga tcacctgttg atgggaaaaa tggtaaaagg
    34981 tgaactcctc caatagcatc tccaaaatgc tcttccaaat tatcatataa gtctttaaga
    35041 ttatttccaa ggctatcaga ataggtaatc aacatggttt tattttgaat tggcatcatt
    35101 actctccttt ttctaattga agccaagtct catatgatct ggcttcataa ataaaattca
    35161 ttttaaatct ctatttatca tcaaactcgt actaatatag actgtgataa acaaagtact
    35221 actttcttgt tttctgcata gaattatcaa caagctaaac tcttcctctg tgtcaaagac
    35281 tatagattcc atgagctctt cttatactct tcgaaaatct cttcaaacca cgtcagcttc
    35341 accttgccgt aggtatggtt actgacttcg tcagtttcat ccacaacctc aaaacagtgt
    35401 tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga gtattacttc
    35461 actgccccgt tgctcattcc tgaaatgata tggcgttgga agaagagata gacaatggtg
    35521 atactgataa tgccgaccac gtaagaggca aagcttggtc cgtagtcgtt gaaatattgg
    35581 cctgcgtagt tgtattggaa caaaggcaga gtccacattt tggaatcccg gttcaagaca
    35641 aggagtggca acatgaagtc attccagaac caaagggcat tgatgatcat ggttgtcgca
    35701 tgcatcggtt tcatcattgg gaagatgatg cggaaatagg ttgtaaattg attagcccca
    35761 tcgatctctg ctgcttcatc cagactttct ggaatcgaga ttttgatata gccaacatag
    35821 agaaagaggg tctgtggaat cgcataggtc aagtagagca agatcaaacc aaaggtatta
    35881 gccaaaccga gtttactcat cataaccgta atcggaatca tgatgacttg gaaaggtacg
    35941 aagattccga ggattaagag ggtatacatg atggtaaagg cttttctttt actcatattg
    36001 cgagcgatgg agtaggctgc catagggata aagatcatta ctgcaagtaa agacaagaca
    36061 gtgatgacga cagagttcca ataatagcct ccaatcccat cagctaagag acggctaaag
    36121 ttgtcccatg tgaagttggt tggaaagcca aagaaattat ctacaatatc cttagtgggt
    36181 ttgaaggaac taaagagggt agcaaggagc ggcactaaaa tcagaaccga tcctagaatc
    36241 aatagaatgt atttgccaat cagggctttt ctttcatctt gtttcatcat gcttctcctc
    36301 ttaaatttca aatttcttag atactctcaa ttggatgatc gaaatcacta caattaagaa
    36361 gaacaagatt acggcaatgg cattggcata accgaattgg ttgtttttaa aggcatagtt
    36421 ataaaccaag agcccaagtg aggttgtggc attgtttgga ccaccaccgg tcatggcaaa
    36481 gacttggtca aaggcagtca gcccaccttt tagggctagg ataaagacca tagagacact
    36541 tggtagcaag taaggcaatt caatgttcca gaaaacttgc ttgctagtcg caccatcaat
    36601 ccttgctgcc tctgtaatct cagttggaat agattgcaaa ccagctagga agatgatgat
    36661 gggcatagcc accccttgcc aaagaaggac aaagacagcc gcaaagattg ctccccactt
    36721 agtccctaaa agactggttt ggaaaaattc aatatgaagg gcatttccaa tcgctggaag
    36781 accgtagttg aagacttgct tgaagatcaa agccactgtc aaaccagata aaacagctgg
    36841 gaagaagaac caagcacgga agaaggtttg gcctttgatt ttagaattca agacacgcgc
    36901 aatgaagatc ccgagtgcaa tctcaccaac caccatggca atcgcaatga ttgcggtaaa
    36961 gccaatcgca ttcatgaatt ttggatccat gaagaggagc ttaaagttgt ttaagccaac
    37021 aaatttgtag ttataagtca atcctgtcca gttggtaaaa ctgtaaaagg ctccttgaaa
    37081 catcggcaca tagaagaaaa ttgcttgtaa caagaggggg atgaccacaa aagcccatgc
    37141 ccaatatttt tgtaatactt ttttcatagt ctctctactc ctaatccaca tccgctttca
    37201 tcgggttaaa gaaggcattc aaatcattga ccatgccttg tttatcaccg gtcaagacat
    37261 agttcatggt caaggtatgg aagtctgctt cactggtcca gtattgttgc aaccagacca
    37321 agtgacgatc cgtaaaggca tattcggtca taccagcaag cggtgaatct tctcctgctt
    37381 gtttgacccc ttcgatcgct gttggagatc cgtccacatc gtagtatttt tgcatgactt
    37441 ctggacgggt catatattcc acaaaggcat tggcttcttt tggatgtttg gtggtggctg
    37501 agatagacca tgccaagtct cccgcaccaa cggttaagct ttgtcctttt tcttttcctg
    37561 gaatcatgaa ggtcccaatc ttaaagttcg gtttttgttc attaatcgct gtgatcgccc
    37621 aagacccatt tggtgtcatg aggacatccc cacgtgcgaa ggctccgata acatcggtat
    37681 agccagcacc ttcccagttc ttttgcttag agccattgat gcgaaggatg tccatgacct
    37741 tgatatcatc tttcataatc ggatccgaca atttaatggc atttggttga gaataacgaa
    37801 ggtattgatt tgcttctttt cctccacctg ttgctgtcgc aaaggctaat tgattgtaac
    37861 cattgagtgt ccaagcatct gcacctgcaa ttccaaatgg tgtttgtcct ttagcaacga
    37921 tatctttgac taactgttca aattcatccc aggtttcagg aaccttcaag cccagttctt
    37981 cgaatttatc tttgttgtag taaattccat aagcattagc tgtaaaagga acgttgtaaa
    38041 ctttttcgtt tacagcatat ttttcagcgt agccattttt cacgcgtttc aggtagtctt
    38101 tgttgctcaa atcttcaaaa acacctgctt ttgcccattc ttgcagttcg atggactgtg
    38161 ggtaaatatt gaccacatca ggcacatctc ctgcgagaac gcgtgtcttc aatacttcac
    38221 cagcatttgg tacattgacg actttgacct tgatcttagg gttttccttc tcaaaatcac
    38281 gagtgatttc ttccaaggtt ttggtcattt cttttttctg gttgaaatac tcgatggtca
    38341 ctgtgccatc cgcagattta ccatagttgg agcaagcgcc gagcccaaac aaagctaaac
    38401 ctgtagttgc aagaagtccg atttttttat accattccat tagaaagcct cctttataaa
    38461 tttatacacc cttattgaac tgcaccccaa aagttagaca gaataaatct aacttttggg
    38521 gtcagtacat atcatagttt tctaaaaata tactgtctac tcaaaaaatc tccttgggat
    38581 aagataacag ttaagcccgc atacattagt tctgcacctg agtaaacttc gccattttcc
    38641 tgtaatttat atagtccctc ttcatccaaa tcttttaatt ttaaagttgt ttccatggtc
    38701 tctacaacag ataaaacgcg aacgtaggtt acaatcgttt gatttccgta attaaattgt
    38761 acagctgctt cattggatac agtatcagga ttaattagtc tatactgctg tcctaactga
    38821 actactggtc gtaattcttt atacaagttc acctgattag caatcgtagc tttctcttca
    38881 tctgataaat ttgtcaaatc aagttcatag cccaaatttc ccatcattgc tacaaggcca
    38941 cgtgtttcta atggtgtcat tcgtcccatc tgatgattcg gtactgctga cacatgagcc
    39001 cccatagaaa tggttggata gagataggat gaaccgtatt gaattggtaa acgtgcaatg
    39061 gcatcagtat tatcactagc ccagacttgt gggaaatagc gcatcatacc aagatcattt
    39121 cgtccaccac caccagagca ggactcaaag agaatatggc tgtgcttctc tgtcagataa
    39181 gaaacgagtt cataaagccc cagcatgtac tgatgagatt gcatctgtgt ctctagataa
    39241 gttaatccat tccctagctt agtgatattg cggttcatat cccatttaat gtaatcaata
    39301 tcatgataaa ataggagttg atctaagaca cttttcaagt attctactac ctgaggattg
    39361 gcaagattaa gtactaattg attccgagaa taagtatgct catagccagg aacctgaata
    39421 gcccagtcag gatgttgacg atacaaatca ctatctacag aaatcatttc gggttctaac
    39481 caaagtccaa actgcaaacc tctttcatgg atagctgaaa tcagactttc tagacttcca
    39541 cccagttttt cctcattaac aacccaatca cctaaagcac gattatcatc aaaacgattg
    39601 ccaaaccaac catcatctaa tacaaaaagt tcaatgccaa ctttcttagc ttcatctgct
    39661 aactctaaca gtttttctct ctgaaagtca aagtaagtag cttcccagtt attgattaga
    39721 attggacgtt cttttttaga aaattcactt agcataatgt gcttcagtac aaaattctga
    39781 ctttcatgac taataccagt taatccctga tctgaatgag tcactaaagc taccggtgtt
    39841 tcaaagtatt cctcaggagc taacttccaa gaaaagtttt ctggattaat gccaatagcc
    39901 acccgaactt cattcaattg atttttttga acaaaagctt caaagttgcc actatacatt
    39961 agttgaatag caaacacatt cccagcatcc tctgtgactc cttgttcgca tagtagaaga
    40021 gctggtgttt gagcatgacc agaagcacct cggtttgaac taatcgaaaa gattccttgt
    40081 tctacctgtt gacgtctaac agtcttttca cgagcataag caccctgcag agttactatt
    40141 tcgtaatctg cagctggaaa atcagccata aaagaaaaat ctttatggat gacaacttcc
    40201 tgattactat tattatctaa tttactgtag ctagcaatag tcgcatcatt attaaaagta
    40261 gtataataca aagtcagact aagttgagcc ttagaatctt ctaacattaa gacaagagtc
    40321 tctgtatcgt ccatgctatg tggagaaggt aagccctgtg gaccattctg accttttaaa
    40381 atctttgctt ctacaaatcg aaagtctgtt acttcagtta cactatgctg aacctgtatg
    40441 gttggtttcc taaaatctcc taagccatgt tgtccaaaaa tctgtcgctg agtatctaaa
    40501 ctaaaggttc gattagtagc cgttggattt cctgaaaagg catggtctcg ttcataaaca
    40561 ctattggaac ctttatagtt cttaatagtc tttcctaaat gtttcaaaag taagtagcca
    40621 tttcgatttt caataatcaa acttagattt ttactctcaa cataaaatag attattctct
    40681 atcctaactc ccatttactt cacctcatca ctttattgat tatattttat cacctgaaat
    40741 cgctttccaa aatagaaaaa tgtctcaaga atatggtaaa atgttaggta ggaggtagca
    40801 catgttagtt ttttcagaat accagactgg aacaatcgac cttgccctaa gcttttatgg
    40861 atatgaggaa tgcacaccta attactcttt tggtccagcc attcgtgata catacgttct
    40921 acattacatt actaaaggac aaggaaaatt tcattacaag ggtaaaattg ttgatttaaa
    40981 agaaggagat ttctttctat taaaaccaga ggaactaacc ttttatcaag cagatagtaa
    41041 agaaccttgg gcctactact ggttaggaat cactggaggg aaagcccctg attattttgc
    41101 tctttcccaa atttctgatc aatcctatct catccaatct gaaacttgtc atacccagac
    41161 tactgcaaaa ctcatctcag acattgtccg cttcgctcag attacaaaat caagtgaatt
    41221 agctcaactc catatcatgg gacaacttca tgaactgatg tttcatctgg gaactattgc
    41281 tcccaatcag aaaaaaaaga atatttcatc aacccaccaa ctctatcttg aatgcaaacg
    41341 attaattgat agccactatc ctcaatcact tacaattcaa gatttagcaa aagaactatc
    41401 cgttcacaga agctacttat caagcgtatt caaagaattt aataccttat cacccaaaga
    41461 atacctactc tacgttcgaa tgcaccgagc tagacaactt ctcgaaaata cccaagagtc
    41521 catcaaggta attgcatact cggtaggttt ttcagatcca ctccattttt cgaaagctta
    41581 taaacaatac tttaatcaga ctccaagtca tacaagaaaa gaatactctc aataccaact
    41641 agtaagaaag gcaacattat gaaatcctac caagctgtct accaaatcct atctaaagaa
    41701 accgactata tcagcggaga aaaaatcgca gaaaaactat ccctaagccg aacagcaatt
    41761 tggaaagcca tcaagcgact agaacaagaa ggcattgaaa ttgatagtat caaaaataga
    41821 ggatataaac tgatgaatgg tgaccttatt cttccagaga ttctagaaga aaatcttcca
    41881 attaaagtca gctttaaacc cgaaacaaaa tcaacacaac tagatgcaaa agaagcaatt
    41941 gatttaggcc atgaagcaaa taccctctat ctagcttcct atcaaacagc aggccgaggc
    42001 cgttttcaac gttccttcta ctcaccacaa ggtggtattt atatgacact ccatcttaaa
    42061 ccaaatctcc cctatgacaa attaccatcc tacacactac ttgtagctgg agctgtctac
    42121 aaagccatta agaacctaac tttaatagat gtcgacataa aatgggtcaa tgatatctat
    42181 ctaaacaatc ataaaattgg aggaatcctt actgaagcaa tgacctctgt agaaactggc
    42241 ttagtcacag atatcattat tggagtaggt atcaatttca ctattaaaga cttccctcag
    42301 gaattaaaag aaaaagctgc cagcttattt aaagctacag ctcctataac aaggaatgaa
    42361 ttgatcatag aaatctggcg tgctttcttc gaaacaccag cagaagagct attataccta
    42421 tacaaaaaac agtcattcat tctaggaaaa gaagtcactt tcacactaga gcaaaaagac
    42481 tacaagggac ttgctaaaga catctcagaa aatggaaaac ttttagttca atgtgataac
    42541 ggaaaagaaa tctggctaaa tagtggcgaa atttctctca atagttggaa gtaaaataac
    42601 acaattataa tataaacgat ataaaaataa cttcagatta gtaattcaat taagttttac
    42661 ggatctgaag ttttattggc tctaaaaata aaaaagagag ttacagactc tcattaaaac
    42721 ggagaataag ggattcgaac ccttgcgcca gttacccgac ctaacgattt agcaaaccgt
    42781 cctcttcagc ctcttgagta attctccaat taatgggcac gagtggactc gaaccaccga
    42841 cctcacgctt atcaggcgtg cgctctaacc aactgagcta cgcgcccaag ttaaaaaact
    42901 tggtaatttg aacaaagttc aaagcgggtg acgagaatcg aactcgcgac aacagcttgg
    42961 aaggctgtag ttttaccact aaactacacc cgcataaata ctatcaataa aatggcgcga
    43021 gacggaatcg aaccgccga
//
LOCUS       DAVBNN010000014        40539 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBNN010000014 DAVBNN010000000
VERSION     DAVBNN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.014"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            3..75
                     /locus_tag="VQ847_000781"
     tRNA            3..75
                     /locus_tag="VQ847_000781"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            81..151
                     /locus_tag="VQ847_000782"
     tRNA            81..151
                     /locus_tag="VQ847_000782"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Gly,seq:tcc)
     gene            186..259
                     /locus_tag="VQ847_000783"
     tRNA            186..259
                     /locus_tag="VQ847_000783"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ile,seq:gat)
     gene            342..431
                     /locus_tag="VQ847_000784"
     tRNA            342..431
                     /locus_tag="VQ847_000784"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Ser,seq:tga)
     gene            445..518
                     /locus_tag="VQ847_000785"
     tRNA            445..518
                     /locus_tag="VQ847_000785"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:479..481,aa:Met,seq:cat)
     gene            522..594
                     /locus_tag="VQ847_000786"
     tRNA            522..594
                     /locus_tag="VQ847_000786"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:555..557,aa:Phe,seq:gaa)
     gene            607..687
                     /locus_tag="VQ847_000787"
     tRNA            607..687
                     /locus_tag="VQ847_000787"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:641..643,aa:Tyr,seq:gta)
     gene            692..762
                     /locus_tag="VQ847_000788"
     tRNA            692..762
                     /locus_tag="VQ847_000788"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:724..726,aa:Trp,seq:cca)
     gene            777..849
                     /locus_tag="VQ847_000789"
     tRNA            777..849
                     /locus_tag="VQ847_000789"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:810..812,aa:His,seq:gtg)
     gene            863..934
                     /locus_tag="VQ847_000790"
     tRNA            863..934
                     /locus_tag="VQ847_000790"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:895..897,aa:Gln,seq:ttg)
     gene            944..1027
                     /locus_tag="VQ847_000791"
     tRNA            944..1027
                     /locus_tag="VQ847_000791"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:978..980,aa:Leu,seq:caa)
     gene            1134..2411
                     /locus_tag="VQ847_000792"
     CDS             1134..2411
                     /locus_tag="VQ847_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3050154.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2487..3971
                     /locus_tag="VQ847_000793"
     CDS             2487..3971
                     /locus_tag="VQ847_000793"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3050155.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            4032..5312
                     /locus_tag="VQ847_000794"
     CDS             4032..5312
                     /locus_tag="VQ847_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3050156.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5316..5936
                     /locus_tag="VQ847_000795"
     CDS             5316..5936
                     /locus_tag="VQ847_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3050157.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6102..7280
                     /locus_tag="VQ847_000796"
     CDS             6102..7280
                     /locus_tag="VQ847_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3050158.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7793..8131
                     /locus_tag="VQ847_000797"
     CDS             7793..8131
                     /locus_tag="VQ847_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3050159.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8142..8510
                     /locus_tag="VQ847_000798"
     CDS             8142..8510
                     /locus_tag="VQ847_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3050160.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8617..9261
                     /gene="pcp"
                     /locus_tag="VQ847_000799"
     CDS             8617..9261
                     /gene="pcp"
                     /locus_tag="VQ847_000799"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3050161.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9289..10146)
                     /locus_tag="VQ847_000800"
     CDS             complement(9289..10146)
                     /locus_tag="VQ847_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3050162.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10276..11418
                     /gene="tgt"
                     /locus_tag="VQ847_000801"
     CDS             10276..11418
                     /gene="tgt"
                     /locus_tag="VQ847_000801"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3050163.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11519..13336
                     /locus_tag="VQ847_000802"
     CDS             11519..13336
                     /locus_tag="VQ847_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3050164.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13489..14640
                     /gene="nagA"
                     /locus_tag="VQ847_000803"
     CDS             13489..14640
                     /gene="nagA"
                     /locus_tag="VQ847_000803"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3050165.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14803..15861
                     /locus_tag="VQ847_000804"
     CDS             14803..15861
                     /locus_tag="VQ847_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3050166.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            16012..16377
                     /locus_tag="VQ847_000805"
     CDS             16012..16377
                     /locus_tag="VQ847_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3050167.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16453..17394
                     /locus_tag="VQ847_000806"
     CDS             16453..17394
                     /locus_tag="VQ847_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3050168.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17342..18358
                     /locus_tag="VQ847_000807"
     CDS             17342..18358
                     /locus_tag="VQ847_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3050169.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18360..18686
                     /gene="comGC"
                     /locus_tag="VQ847_000808"
     CDS             18360..18686
                     /gene="comGC"
                     /locus_tag="VQ847_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET3050170.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGA
                     NRKVND"
     gene            18679..19083
                     /locus_tag="VQ847_000809"
     CDS             18679..19083
                     /locus_tag="VQ847_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3050171.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19088..19348
                     /locus_tag="VQ847_000810"
     CDS             19088..19348
                     /locus_tag="VQ847_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050172.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19311..19772
                     /locus_tag="VQ847_000811"
     CDS             19311..19772
                     /locus_tag="VQ847_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3050173.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19750..20163
                     /locus_tag="VQ847_000812"
     CDS             19750..20163
                     /locus_tag="VQ847_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3050174.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20300..20894
                     /locus_tag="VQ847_000813"
                     /pseudo
     CDS             20300..20894
                     /locus_tag="VQ847_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20955..21908
                     /locus_tag="VQ847_000814"
     CDS             20955..21908
                     /locus_tag="VQ847_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3050175.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21959..23149
                     /locus_tag="VQ847_000815"
     CDS             21959..23149
                     /locus_tag="VQ847_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3050176.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23298..23669
                     /gene="rnpA"
                     /locus_tag="VQ847_000816"
     CDS             23298..23669
                     /gene="rnpA"
                     /locus_tag="VQ847_000816"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3050177.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23644..24468
                     /locus_tag="VQ847_000817"
     CDS             23644..24468
                     /locus_tag="VQ847_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3050178.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24487..25473
                     /locus_tag="VQ847_000818"
     CDS             24487..25473
                     /locus_tag="VQ847_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3050179.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25524..26147
                     /locus_tag="VQ847_000819"
     CDS             25524..26147
                     /locus_tag="VQ847_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3050180.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26278..27735
                     /locus_tag="VQ847_000820"
     CDS             26278..27735
                     /locus_tag="VQ847_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3050181.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27758..28039
                     /locus_tag="VQ847_000821"
     CDS             27758..28039
                     /locus_tag="VQ847_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3050182.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28116..28601
                     /locus_tag="VQ847_000822"
     CDS             28116..28601
                     /locus_tag="VQ847_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3050183.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28618..29283
                     /locus_tag="VQ847_000823"
     CDS             28618..29283
                     /locus_tag="VQ847_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3050184.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29287..30150
                     /locus_tag="VQ847_000824"
     CDS             29287..30150
                     /locus_tag="VQ847_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3050185.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            30152..30856
                     /locus_tag="VQ847_000825"
     CDS             30152..30856
                     /locus_tag="VQ847_000825"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3050186.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            31035..32708
                     /locus_tag="VQ847_000826"
     CDS             31035..32708
                     /locus_tag="VQ847_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3050187.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32820..33911
                     /gene="ulaG"
                     /locus_tag="VQ847_000827"
     CDS             32820..33911
                     /gene="ulaG"
                     /locus_tag="VQ847_000827"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3050188.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            34025..36001
                     /gene="tkt"
                     /locus_tag="VQ847_000828"
     CDS             34025..36001
                     /gene="tkt"
                     /locus_tag="VQ847_000828"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3050189.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            36118..36417
                     /gene="yajC"
                     /locus_tag="VQ847_000829"
     CDS             36118..36417
                     /gene="yajC"
                     /locus_tag="VQ847_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3050190.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36463..36891
                     /locus_tag="VQ847_000830"
     CDS             36463..36891
                     /locus_tag="VQ847_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3050191.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36893..37303
                     /locus_tag="VQ847_000831"
     CDS             36893..37303
                     /locus_tag="VQ847_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050192.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37602..40253
                     /gene="adhE"
                     /locus_tag="VQ847_000832"
                     /gene_synonym="adhC"
     CDS             37602..40253
                     /gene="adhE"
                     /locus_tag="VQ847_000832"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3050193.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12294 a         7268 c         9128 g        11849 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct
      121 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttctttgta ccaagttttt
      181 gacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      241 tcgagtccac tcgtgcccat agtgtttagt ccattactag gggattggaa tattatctgt
      301 tcactaagag gacacgggct tgttcccgta taaactattt tggaggatta cccaagtccg
      361 gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc
      421 cacatcctcc ttttatatta ttaacgcggg atggagcagc tcggtagctc gtcgggctca
      481 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
      541 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccatttata
      601 tattttggaa gggtagcgaa gaggctaaac gcggcggact gtaaatccgc tccttcgggt
      661 tcgggggttc gaatccctcc ccttccattt tacgggcata gtttaaaggt agaactaagg
      721 tctccaaaac cttcagtgtg ggttcaattc ctactgcccg tgttaataga attatggcgg
      781 gtgtggtgaa gtggttaaca caccagattg tggctctggc atgcgtgggt tcgatcccca
      841 tcactcgcct attttatatt attggggtat agccaagcgg taaggcaagg gactttgact
      901 ccctcatgcg ttggttcgaa tccagctacc ccagttacta tttgccggcg tggcggaatt
      961 ggcagacgcg ctggactcaa aatccagtgt ccgcaaggac gtgccggttc gaccccggcc
     1021 gccggtatag tatagtgtta ggaacgttgt tattcttcgt tcctttttta tattattttt
     1081 ggtataatta tagttattca aattttattt agattaagaa agtgtagggt agtatgtctt
     1141 gttctatcga tttattaaaa catcggtatt tgaaaaatat taaagaaaat cctgaattgt
     1201 ttgtcggaat tgagttggag tatcctgttg caagtttaga aggggatgct acagatgttg
     1261 aagttataaa ggatctattt cattatttag tttctacttt ggatctcacc gtagcaaagg
     1321 tagatgattt tggcaatctg atccagttag tagatccgat aagtcaggat gctattttat
     1381 ttgaagtttc ctatacaacg attgagtttg catttggtaa ggctgaaacg attcaagagg
     1441 tcgaaaatcg tttcaataat tatatgaatg taattcagag aaagttagct gaatcaaatc
     1501 atgctattgt tggctgtggt atccatccca actgggataa aaatgagaat tgtccagtgg
     1561 cttatccacg ctatcagatg ttgatggatt atttgaattt gagtagaaat attattaaat
     1621 cagatttaca tcatttccct gaatatggta cttttatctg tgggagccag gttcagctgg
     1681 atatttcaaa aaccaactac ttacgggtga ttaatgcttt tactcaaatt gaagcggcta
     1741 aggcttattt atttgcaaac tctgaatttt cgggtgcgga ttgggatacg aaaatttcaa
     1801 gggatatttt ctgggaagaa tctatgcatg gtatctatcc agagaatgtt ggggtcaatg
     1861 ctagactcct taatgatgaa gctgattttt ttgactatct aaatcattct gcgattttta
     1921 ctgcggaacg tgatgggcag acctattatt tttatcctat tcaggctggg gactatttgg
     1981 ctacgtccga aatccaagca tttgctctga atggggatga ggttattatt tacccccaag
     2041 agaaggattt tgaaactcat cgtagttacc agtaccaaga tttaacgact cgaggaacag
     2101 ttgagtttcg tagtgtgtgt acacagccac ttgataggac ttttgcttct gcagcttttc
     2161 acttgggatt attggttaat ttagacaagt tagaagctta cttagaaaca gcacctttct
     2221 ttaaagtatt tggttatgat tacaagtctt taaggagaca attttctaag aaaaatctta
     2281 cagatgagga agaaactacg attattgaat tttccaaaga cttactccta ctagctgagg
     2341 agggactagt ggtgagaaat aaggaagaaa tgacctattt acagcctttg agagaagaat
     2401 tgagcctata atttctctta taaagggaga attttctgaa aaatcatgat ataatggacg
     2461 agactataga taaaggatag agagtaatga cattagttta tcaatcaacg cgtgatgcca
     2521 acaatacagt aactgccagc caagcaattt tgcaaggttt ggcgacggac ggcggtttgt
     2581 ttacaccggt tacttatcca aaggtagatt tggactttga caaattgaaa gatgcttctt
     2641 accaggaagt tgctaagcta gttttgtcag catttttaga tgactttaca gctgaggagt
     2701 tggactactg tatcaacaat gcctacgata gcaaatttga tactccagct attgcaccat
     2761 tagtgaaatt agatgggcaa tacaatttgg aacttttcca tggttcaacg attgccttta
     2821 aggatatggc cttgtctatt ttgccatact ttatgacgac tgctgctaag aaacatggtt
     2881 tggagaacaa gattgttatc ttgacagcga catctggtga cacggggaaa gctgctatgg
     2941 cggggtttgc ggatgtgcct ggtactgaga ttatcgtctt ttatccaaag ggtggtgtca
     3001 gcaaggtaca agagttgcaa atgaccactc agaatggtga caatactcat gttattgcta
     3061 ttgatggtaa ttttgacgat gcgcaaacaa atgtgaagca catgtttaac gacgtggctc
     3121 ttcgtgaaaa attgactacc aacaagttgc aattttcatc agctaactct atgaacattg
     3181 gtcgtctggt gccacaaatt gtttattatg tttatgctta cgctcaattg gttaagactg
     3241 gtgaaattgt agctggtgaa aaggttaact tcacagtacc aacaggaaac tttggaaata
     3301 tcttggctgc cttttatgcc aaacaaatcg gcctaccagt tggcaagcta atctgtgctt
     3361 caaatgacaa taatgtcttg acagacttct ttaaaacacg tgtctatgac aaaaaacgtg
     3421 agtttaaggt aacaaccagc ccatctatgg atatcttggt atcttcaaac ttggagcgct
     3481 tgattttcca tcttttggga aataatgctg aaaagacagc tgaacttatg aatgccttga
     3541 acacgcaagg acaatataag ttgacagact ttgatgcaga gattttggac ctctttgcag
     3601 ctgaatatgc gactgaggaa gaaacagcgg cagaaatcaa gcgtgtttat gagtcagatt
     3661 cttatattga ggatccacat acggcggttg cctcagcagt ttatagaaaa taccaagcgg
     3721 ttactggaga tgtaactaag acagtgattg cttcaacagc tagtccatac aagttcccag
     3781 tagttgcagt agaagctgta actggaaaag caggtttgac agactttgaa gccttggctc
     3841 aattacatga aatctcaggc gttgcagtgc caccagcagt tgatgggctt gaaatagctc
     3901 caattcgtca caagacaaca gtggcagctg ctgacatgca agcagcggtt gaggcttatt
     3961 taggacttta agacagaggg agcaaactcg gttgggaaac caactgagtt tcttttcatc
     4021 aggaggagag attgtttaag aaaaataaag acattcttaa tattgcattg ccagctatgg
     4081 gtgaaaactt tttgcagatg ctaatgggaa tggtggacag ttatttggtt gctcatttag
     4141 gattgatagc tatttcaggg gtttcagtag ctggtaatat tatcaccatt tatcaggcga
     4201 ttttcatcgc tctgggagct gctatttcca gtgttatttc aaaaagcata gggcagaaag
     4261 accagtcgaa gttggcctat catgtgactg aggcgttgaa gattacctta ctattaagtt
     4321 tccttttagg atttttgtcc atcttcgctg ggaaagagat gataggactt ttggggacgg
     4381 agagggatgt agctgagagt ggtggactgt atctatcttt ggtaggcgga tcgattgttc
     4441 tcttaggttt aatgactagt ttgggagcct tgattcgtgc aacgcataat ccacgtctgc
     4501 ctctctatgt tagtttttta tccaatgcct tgaatattct tttttcaagt ctagctattt
     4561 ttgttctgga tatggggata gctggtgttg cttgggggac aattctgtct cgtttggttg
     4621 gtcttgtgat tttgtggtca caattaaaac tgccttatgg gaagctaact tttggtttag
     4681 ataaggaact gttgaccttg gctttaccag cagctggaga gcgacttatg atgagagctg
     4741 gagatgtagt gatcattgcc ttggtcgttt cttttgggac ggaggcagtt gctgggaatg
     4801 caatcggaga agtcttgacc cagtttaact atatgcctgc ctttggtgtc gctatggcaa
     4861 cggtcatgct gttggcccga gcagttggag aggatgattg gaaaagagtt gctagtttga
     4921 gtaaacaaac cttttggctt tctctgttcc tcatgttgcc cctgtccttt agtatatatg
     4981 tcttgggtgt accattaact catctctata cgactgattc tctagcggtg gaggctagtg
     5041 ttctagtgac actgttttca ctacttggta cccctatgac gacaggaaca gtcatctata
     5101 cggcagtctg gcagggatta ggaaatgcac gcctcccttt ttatgcgaca agtataggca
     5161 tgtggtgtat ccgcattggg acaggatatc tgatggggat tgtgcttggt tggggcttgc
     5221 ctggtatttg ggcagggtct ctcttggata atggttttcg ctggttattt ctacgctatc
     5281 gttaccagcg ctatatgagc ttgaaaggat aggaaatgca aaaaacagct tttatttggg
     5341 atttagacgg gactttattg gactcttacg aagcgatttt atcagggatt gaggagactt
     5401 ttgctcagtt ttctattcct tatgataagg agaaggtgag agagtttatc ttcaagtatt
     5461 cggtgcaaaa tttgcttgtg cgggtggcag aagatagaaa tctggatgtt gaggtgctaa
     5521 atcaggtgcg tgcccagagt ctggctgaga agaatgctca ggtagttttg atgccaggtg
     5581 cgcgtgaggt gctagcttgg gcagacgaat caggaattca gcagtttata tatactcata
     5641 aggggaacaa cgcttttacc attctcaagg acttgggggt ggaatcctat tttacagaga
     5701 ttttaaccag tcagagtggc tttgtgcgga agccaagtcc agaagcggct acctatctgc
     5761 tagataagta tcagttgaat tctgataata cttattatat aggggatcgg actctggatg
     5821 tggaatttgc ccagaatagt gggattcaaa gtatcaactt tttagagtct acttatgaag
     5881 ggaatcacag gattcaagcg ttagcagata tttcccgtat ttttgagact aagtgataaa
     5941 aagattgtgt cagttttgtg acagagacct aacaaactat ttcaagtaat ctagtttgtt
     6001 acaaggaata gacagttctg ttaaataggc ccgagagggc tttttttcta cattttttgt
     6061 gttatgatag acaggtactc atttgaaagg aatttgaagg aatgaagaaa agaatgttat
     6121 tagcgtcaac agtagccttg tcatttgccc cagtattggc aactcaagca gaagaagttc
     6181 tttggactgc acgtagtgtt gagcaaatcc aaaacgattt gactaaaacg gacaacaaaa
     6241 caagttatac cgtacagtat ggtgatactt tgagcaccat tgcagaagcc ttgggtgtag
     6301 atgtcacagt gcttgcgaat ctgaacaaaa tcactaatat ggacttgatt ttcccagaaa
     6361 ctgttttgac aacgactgtc aatgaagcag aagaagtaac ggaagttgaa atccaaacac
     6421 ctcaagcaga ttctagtgaa gaagtgacaa ctgcgacagc agatttgaca accaatcaag
     6481 tgaccgttga tgatcaaact gttcaagttg cagatctttc tcaaccaatt gcagaagctc
     6541 caaaagaagt agcatcaaat tcagaagttg cagagacagt gactgctgca gaagaagtgg
     6601 cactatctac agactctact acgccagagg gacaaccagc cgaaacaact agtccagttg
     6661 aagaagtagc tcctcaggca acgactctag ctgagaagca ggaaacacaa gtgagctctc
     6721 aaaccgagtc agcagtggaa gcaactacaa tgccagtaga agaaaaagca accgaagcaa
     6781 ctacaacaag ttcagaagca aaagaagtag catcatcaaa tggagctaca gcagcagttt
     6841 ctacttatca accagaagag acgaaaataa tttcaacaac ttacgaggct ccagctgcgc
     6901 ccgattatgc tggacttgca gtaacaaaat ctgaaaatgc aggtcttcaa ccacaaacag
     6961 ctgcctttaa agaagaaatt gctaacttgt ttggcattac atcctttagt ggttatcgtc
     7021 caggagacag tggagatcac ggaaaaggtt tggctatcga ttttatggta ccagaacgtt
     7081 cagaattagg ggataagatt gcggaatatg ctattcaaaa tatggccagc cgtggcatta
     7141 gttacatcat ctggaaacaa cgtttctatg ctccattcga tagcaaatat gggccagcta
     7201 acacttggaa tccaatgcca gaccgtggta gtgtgacaga aaatcactat gaccacgttc
     7261 acgtttcaat gaatggataa acccgacttg gtaacatcat tttgacgaat gagatctagc
     7321 tttcgtgata ggaagcgatt ctcgttcgtt ttttctttgt catactcttc gaaaatctct
     7381 tcaaacaacg tcagttttat ctgaaacctc aaagctgtgc tttgagcaac ctgcgactag
     7441 cttcctagtt tgctttttga ttttcattga gtatcaattt gaatggaaaa tggaaagtta
     7501 tcatcttgta atgagttaag caacattctt gcaatctatt ttatagtaga ttgaaactag
     7561 aatagtacac aactgcttct aaaacattgt tagaaatcga tttgactgtc ctgatcgatt
     7621 tgtcctgctc ttatttcatt tcactatact ttatattata attgactggt caaatattga
     7681 taaatcaata aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc
     7741 cgcttgtctg agcaagtgag tacgcaattg tttgaaaaag cttgggatta gtttgacacg
     7801 gtatcagatt ttactgtttt tgctggagca ttctccttgt aaccaaatgg cggttcagga
     7861 gcgtttgaaa attgatcagg ctgctttgac acggaatttc aagattttgg aaacggaagg
     7921 tttggtggag cgtcatcgta atcctgaaaa tcagcgggaa gtattggtag aggctgcgaa
     7981 gtatgccaag gagcagttag tggtgaatcc ccctctgcag catatcaagg ttaaggaaga
     8041 gatggaaagt atcttaacag agtttgagag aacagaactc agccgtttat taaataaatt
     8101 ggttttgggt attgaaaata tagaaattta aggagaaata gatgtcaatt attacaatta
     8161 ttttaacaac gatcgttgct ttggagcatt tttacatttt ttatttggaa agtattgcca
     8221 cgcaatcaga tgcgactagt cgtgtattta atatggaaaa ggaagaattg gctcatccgt
     8281 cagtaagttc attgttcaaa aatcaaggga tttataaggc tctgctagga gtctttctct
     8341 tgtatgtcat ttatttctca cagaatttag aaattgtgac tatttttgtc ttatttgtga
     8401 ttggtgctgc gacttacggc tctttaacag cggataaaaa aattattttg aagcaaggtg
     8461 gatcagctat tttggccttg attagtattt tactctttaa atacacttga aggtcgattt
     8521 taatctcgct aatccttttt aatccagaat aagggaaata tgttatactt gtttttaaga
     8581 aaaaagtctc attgaattgg ttttgaggag ttagaaatga aagtattagt gacaggtttt
     8641 gagccctttg gaggggaaaa gggcaatcca actttggagg ccattaaagg tttaccagct
     8701 gaaatccatg gtgctgaggt ccgttggcta gaggtgccga cagtttttca caaatctgct
     8761 caagtattgg aagaagagat gaatcgttat caacctgact ttgtcctttg tattgggcaa
     8821 gctggtggaa gaactagtgt gacacctgaa cgagtggcca ttaatcaaga cgatgcacgc
     8881 atttctgata acgaagataa tcaaccgatt gaccgtccca ttcgcccaga tggtgcttcg
     8941 gcctacttta gtagtttgcc gattaaagcg atggttcaag ctataaaaaa agagggctta
     9001 ccggcctctg tttccaatac ggcagggact tttgtctgca gccatttgat gtatcaggct
     9061 ctctatttgg tagaaaagaa atttccatat gttaaggcag gttttatgca tattccttat
     9121 atgatggaac aggtggtgaa cagaccgact actccaacta tgagtttagt ggatattcgg
     9181 cgagggatag aagcagcaat cggcgctatg atagaacatg gagatcagga actcaagttg
     9241 gtaggcggag aaactcattg atagaaaaaa gcttgagggg aaaaaccttc aagcttttgg
     9301 acgttttcga gccaatactg ctcggtaaaa cataatttta gtgcattgga tataaggtag
     9361 gagtgaaaaa ctagcaatgc caaaggtaat ccaattgagg aagtaccaag gaagaagctg
     9421 taaatctagg acaaagtgct ggaacttgta gcccttcata aaggaacggc tagtttttag
     9481 gattcgtctt ggtgggacct gtcctaggtc tagactataa cagagaagaa attccacctg
     9541 tgaataggca taatactgtg gaatatagag gatatttcct acaatgatca agatgagact
     9601 tgcaagaaag tagagtccaa agaccatgag gaaacgctcg gtttcaactg atgagagatc
     9661 tagatttgga aactcaggat gtagggtgac gaattttttg gctaaaaagc tactataaaa
     9721 gaggaggtaa atcccaagta aattagggat actccataaa aagagataga aacgtttgag
     9781 aagtagggtc aaaaaggttt gagaaaagcg ctcctcatca aagagagcta ggctgttttt
     9841 tacagatggc tccgttttag aatctttcat gagtgtcagt gttgcataga cggaactggt
     9901 caaaagaata gtcccgataa aggagactag tagaggaaag aggtaggttt gaagtatttg
     9961 gccaagtatg ctgaaaaatg gctgttctaa aacagtcccg tggatccgag ataagggatt
    10021 aagaaaacca gataagatga ccagcatact gggaaggata tagaggagaa agagacgggg
    10081 ggtgtcagcc tgaaaatgtt ttgactcctg acgaattgtt tttaaatcaa tttttggata
    10141 gttcattctc ttattatacc atagttctta tacatagttc gtgacagttc ctactttttt
    10201 tgataaaatc atacagtgtg tccttgggca cactgtatga actgggactg tctttcccag
    10261 cttcggaggt aaaaaatgtc agattcacca atcaaatatc gtttgattaa gaaagaaaaa
    10321 cacacaggag ctcgtctagg agaaatcatc actccccacg gtacctttcc gacacctatg
    10381 tttatgccag ttgggacaca agccactgtc aaaactcagt cacctgaaga attgaaggag
    10441 atgggttcgg gaattatcct atcaaacacc tatcatctct ggcttcgccc tggagatgaa
    10501 ctcattgcac gcgctggtgg tctccacaag ttcatgaatt gggaccagcc tatcttgaca
    10561 gatagtggtg gttttcaggt ttattcttta gcagatagcc gtaatatcac agaagaagga
    10621 gtaaccttta aaaatcatct aaatggttct aagatgctcc tatccccaga aaaagccatc
    10681 tctattcaga ataatctggg ttcagacatc atgatgtcct ttgatgaatg tcctcagttt
    10741 tatcaacctt atgactacgt taagaaatcg atcgagcgta ccagccgttg ggctgagcgt
    10801 ggtttgaagg ctcaccgtcg tccacatgac caaggtttgt ttggaattgt gcaaggtgca
    10861 ggatttgaag accttcgccg ccaatcagct cacgatcttg tcagcatgga tttctcaggc
    10921 tactctatcg gtggtttggc agtgggagaa acccatgaag agatgaatgc ggtcttggac
    10981 tttacaactc aactgctgcc tgaaaataaa cctcgttatc tgatgggtgt gggagcgcca
    11041 gatagcttga tcgatggggt cattcgtggg gtggatatgt ttgactgtgt cttaccgact
    11101 cgaattgctc gtaacgggac ttgtatgacc agtcaaggac gtttggttgt gaaaaatgcc
    11161 cagtttgctg aggactttac gccactggat cctgagtgtg attgctacac atgtaataac
    11221 tatacacgcg cttaccttcg tcacctgctc aaggctgatg aaacctttgg tatccgcttg
    11281 actagctacc acaatcttta cttcttgctt aacctgatga agcaagtgcg acaagccatc
    11341 atggatgaca atctcttgga attccgtaag tattttgtgg aaaaatatgg ctataataag
    11401 tcaggacgta atttctaaaa tggaattgat ataagctaaa aatcctaagt tttctcttag
    11461 gatttttctt ctttttttga tagaataaag tgtacaatga aaggaagaat aaactcgtat
    11521 gcgcattaaa tggttttcct tgattaggat tataggttta cttttggtac tcttgtatca
    11581 cttctttcag acgatctttc ctggaggatt tttcggggta gatgtctttt tcacattttc
    11641 aggtttcctg attacagctc tactcattga agaattttct aagaacaatg agattgattt
    11701 gataggattt tttagaagac gcttttatcg gattgtgcca cctgtggttt tgatggtctt
    11761 ggtgaccatg ccttttactt tcttggttcg ccaagactat gttgctggaa ttggtggcca
    11821 gattgcgggc gtcttaggct ttatgaccaa cttctatgaa ctcttaacag gtgggagtta
    11881 tgaatctcag ttcattcctc atttgtttgt tcataattgg agtttggcag ttgaggttca
    11941 ctactatatt ctttggggat tggcagtttg gttcttatcc aaacaagcta aatcaaatgg
    12001 tcagttgaag gggatgatct ttctcttatc tgctactgcc ttcttaatca gtttcttctc
    12061 catgtttatt ggtagttttc tagtgacctc ttattcctct gtttatttct ccagtttaac
    12121 tcatgtctat ccattctttt tgggaagtat gttagcaact attgtaggcg ttcgtcagac
    12181 gacttccctc gtcaagcagt tggataaaat ctgggattta cgaaagactt tagtagtttt
    12241 tggaggaggc tttggtttcc tagttctttt gactttcttt gtcaaattca cttatctttt
    12301 tgcctatctt atcggcttct tgcttgccag tcttgcagct cttgccatga ttctggcggc
    12361 gcgtgtctta catgaaaaga cacatcatat acaggagccg aagattatca gctttttagc
    12421 ggatactagc tatgcggttt atcttttcca ttggcctttc tatatcattt tctcacagtt
    12481 gacatcaaat cttcttgctg tattactgac tctgatttgt tcttatggct ttgccagtct
    12541 gtcattttat gtattggaac cttggattgc aggcaagaac acacctattt tacaaactct
    12601 tcgtcccctg ccttatattc acgcaattct tgcagcaggt acaggaatct tgaccttcat
    12661 tgtctgcatg gtgaccttgt tggcaccaca agtgggagcg tttgagacag acttgactgt
    12721 caatggcttg aagcaagctg caacaaatat tggccagacc aaggtgatgg cagaacgggc
    12781 agatgcaaac agtttgggaa ttgctgatgg cactatgtta attggtgact cagtggcttt
    12841 aagggcaaat acagcactac agacagctct tcctggagca cagattaacg cgcaggtcag
    12901 cgtaacaacc aagaccgcaa atgaaatcat gctaaataat agccagaata aatttttacc
    12961 taagacggtg gtcattgcga ctggggtaaa taatcctgag aattacaagg atgactggga
    13021 cagtatcgtg aaaaatcttc ctaagggaca ccatatgatt ttggtgactc cttatgaggg
    13081 tgataagaca aaagagacct atgccatcgt tgagaaggct gctgcctata tgagagaatt
    13141 ggcagagaag acaccttaca ttacgatagc agattggaat caagttgcga aagagcatcc
    13201 agaaatttgg gctggaacag accaggttca tttcgggagt gagagtagca ctatcgaagc
    13261 aggagcaaaa ttgtatgcag atacgattgc cacagctttg cagacagctc aagacaagcc
    13321 ggttaaatca aaataacttg tattaaaaaa gagaagagtt ggagaaatcc agctctttta
    13381 aaatatctcc aaaaaatagg tctataccat ttacaaataa aaaagaaagg tttataatgt
    13441 aattgacata ataaattgta gaatcaatct tttaaggagg ttaacattat gcctaactat
    13501 attaaagcgg atcagttttt ctacccacac ggagttcgtc gaggtggtta cttggaactt
    13561 gtggacggca agtttggaaa acatgtagag cagattcctg aaggggctga ggtgattgac
    13621 tatacaggtt atagcattgc cccaggtctt gtggatactc atattcatgg atatgcaggt
    13681 gtagatgtga tggacaacaa cattgaaggt acattgcata ctatgagtga aggacttctt
    13741 agtaccggtg ttaccagttt cttacccaca actttaacag ccacttatga gcaattgctt
    13801 gcagtcactg aaaatcttgg aaaccattat aaagaagcaa caggtgctaa gattcgtggg
    13861 atttattatg aaggtccata tttcacagaa acttttaagg gggcacaaaa tccaacttat
    13921 atgagagacc cgggtgttga ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt
    13981 aataaaattg cccttgcacc agaacgtgat ggggtggaag actttgttcg tacagttacg
    14041 ggcgaaggtg tgacggttgc tcttggacat tcaaacgcga cttttgatga agccaaaaaa
    14101 gcagtcgatg ctggagcgag tgtttgggtg catgcctaca atggaatgcg tgggttgact
    14161 caccgtgaat tgggtatggt tggagccatg taccaattgc cacataccta tgcagagttg
    14221 atctgtgatg gtcaccacgt agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga
    14281 acagaaaaca tcgctcttat cacagactgt atgacagctg ggggattgga agacggagat
    14341 tatatgttgg gagaattccc agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca
    14401 ggtaacttgg caggttctat cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg
    14461 ggaattgcga atccgcatga agcagtcatg atggccagct tcaacccagc taaatccgtt
    14521 cacatcgatg acgtctgtgg ccaaatccgt gaaggctacg acgctgactt catcgtatta
    14581 gataaagatt tggaattggt agcaacctac ctagatggcg tgaaacgtta tcaagcataa
    14641 gagagaaggc agaagttaga gactaacttc tgctttttta tacagggtac tttactggta
    14701 aataaaaagt taaaaaaatc acaaaaaaag cttgaagaaa caaagaaaaa tgcttacaat
    14761 tgaactataa atattacaaa taaaaaaacg gaggagtgct ttatgaaagc ctatacttat
    14821 gttaaaccag gacttgcttc ttttgttgat gtagacaaac cagttattcg caagccaaca
    14881 gacgctattg tgcgtattgt aaaaaccact atttgtggaa cagacctcca tattatcaaa
    14941 ggggatgttc ctacttgcca aagtggtacc attcttggcc acgaagggat tgggattgtt
    15001 gaagaagttg gggaaggagt ttccaacttc aaaaaaggtg acaaggtctt gatttcttgc
    15061 gtctgtgcct gtggtaaatg ctactactgt aaaaaaggaa tttatgccca ctgtgaagac
    15121 gaagggggct ggattttcgg tcacttgatt gatggtatgc aggctgaata tctacgtgtc
    15181 cctcatgcag ataatactct ttaccatact ccagaagact tgtcagatga agctttggtt
    15241 atgctgtcag acattctgcc tactggatat gaaattggtg tcttaaaagg gaaagtagaa
    15301 cctggttgca gcgtagccat tattggttca ggtccagttg gattggctgc tcttttaaca
    15361 gcccaattct attcaccagc taaattgatt atggtagacc tagacgataa ccgcttggaa
    15421 actgccctat cattcggtgc gactcataag gttaattctt cagaccctaa aaaagccatt
    15481 aaagaaattt atgatttgac agatggtcgt ggtgtggatg tcgctatcga agctgtaggg
    15541 attcctgaaa catttgattt ctgtcaaaag attatcggtg tagacggaac ggttgccaac
    15601 tgtggtgtgc atggtaaacc agttgaattc gatttagata aactttggat tcgcaacatc
    15661 aatgtaacaa ctggtttggt atctacaaat acgactccac aattgttgaa agcacttgaa
    15721 agtcataaga ttgaaccgga aaaattggta actcactatt tcaaactcag tgaaattgaa
    15781 aaagcctacg aagtcttcag taaggcagca gaccaccatg ccattaaggt cattatcgaa
    15841 aacgatatct cagaagccta agtagtaaaa atatttttgt acataagcaa atagaaattc
    15901 agtcatccat cagatggctg gattttttat caaaaaatta agaaatgagc atatttcttt
    15961 ccttgtctgg cggaattggt tataatatac ggtacaaagg aatgaatgaa tatgtatcgt
    16021 gttatagaaa tgtacggaga ttttgaaccg tggtggttct tagaaggttg ggaagaagat
    16081 attgtagcaa gtagaaaatt tgaccagtat tatgatgctc tcaaatacta caaaacttgc
    16141 tggtttagat tggaacaaga atcccctctt tataaaagta gaagcgactt gatgaccatt
    16201 ttttgggacc cggaagacca acgctggtgt gatgaatgtg atgagtattt acaacaatac
    16261 cattctttgg ctcttttgca ggatgagcag gttatcccag acgaaaaact acgctcaggc
    16321 tatgaaaaac aaaccagtca ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga
    16381 aaagtaactt ttttggagtt gcttttttta tttttctaac gctttgcgaa tagtataggt
    16441 gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgttcagc tcggaaaaaa
    16501 gggacgcagg atatttattt tgtccctaag ttagacgcct atgagcttca tatgagggta
    16561 ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc cgttatcagt
    16621 cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc
    16681 tgtgattatg cctatgacca gaagatggcg tctctacgtt tatctactgt aggcgattat
    16741 cggggacatg agagtttggt tatccgtttg ttgcacgatg aggagcagga cttgcatttt
    16801 tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact ctatcttttt
    16861 gctggcccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa gtcactcttt
    16921 aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga cgacatgctt
    16981 cagttgcagt tgaacgaagc aatcggccta acctatgaaa atctaatcaa actttccttg
    17041 cgtcatcgac cagatctctt gattatcgga gaaattcgtg acagcgagac ggcgcgtgca
    17101 gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc caagagtatc
    17161 cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt
    17221 ctgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga ctttgcaaac
    17281 agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca gcttcttaaa
    17341 gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa
    17401 aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg tggagactat
    17461 ctccttttta gataggagtg ctttgttgga caagcagtgt gtgatccaga tgcgtgtggg
    17521 cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt caagtgctat
    17581 tgtcactcag ttatccctag ctgaagttca tggcaatctc cacctgagtt tgggaaagat
    17641 agaagaatat ctggacaatc tggccaaggt caagaaaaaa ttgattgaag tagcgaccta
    17701 tcccttgatt ttgctgtttt ttcttctctt aatcatgctg gggctacgga attacctgct
    17761 cccacaactg gatagtagca atattgccac ccgaattatc ggtaatctgc cccaaatttt
    17821 tctaggcatg gcagggcttg tttccgtgct tgccctttta gcactaactt tttataaaag
    17881 aagttctaag atgaatgtct tttctatctt agcacgcctt ccctttattg gaatctttgt
    17941 gcagacctat ttgacagcct attatgcacg tgaatggggg aatatgattt cacagggaat
    18001 ggagttgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct ttaaagaaat
    18061 cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac
    18121 ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag ttaagtccaa
    18181 gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt ttacccgagt
    18241 caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac tgattatcgt
    18301 tttactttat gcggcaatgc tcatgcccat gtatcaaaat atggaggtaa atttttaaaa
    18361 tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga
    18421 tgttggtggt cttgctgatt atcagcgtgc ttttcttgct ctttgtacct aatctgacca
    18481 agcaaaaaga agcagtcaat gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc
    18541 aggcagaact ttatagcttg gaaaagaatg aagatgctag cctaagcaag ttaaaagacg
    18601 atgggcgaat cacggaagaa caggttaaag cttataaaga atacaatgat aaaaatgtag
    18661 gagcaaatcg taaagtcaat gattaaggcc tttaccatgc tggaaagtct cttggttttg
    18721 ggtcttgtga gtatccttgc cttgggcttg tccggctctg ttcagtccac ttttgcggca
    18781 gtagaggaac agattttctt tatggaattt gaagaactct atcgggaaac ccaaaaacgc
    18841 agtgtagcca gtcagcaaaa gactagtctg aacttagatg ggcagacgat tagcaatggc
    18901 agtcaaaagt tgccagtccc taaaggaatt caggtcccat caggccaaag tattacattt
    18961 gaccgtgctg ggggcaattc gtccctggct aaggttgaat ttcagaccag taaaggagcg
    19021 attcgctatc aattatatct aggaaatgga aaaattaaac gcattaagga aacaaaaaat
    19081 tagggcagtg attttactgg aagcagtagt cgctctagct atctttgcca gcattgcgac
    19141 cctccttttg ggacaaattc aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga
    19201 agaagtcttg agggtagcta agatggcctt gcagacgggg caaaatcagg taagcatcaa
    19261 cggagttgag attcaggtat tttctagtga aaaaggattg gaggtctacc atggttcaga
    19321 acagttgttg gcaatcaaag agccataagg tcaaggcttt taccttgtta gaatccctgc
    19381 ttgccctcat tgtcatcagt gggggattac tcctttttca agctatgagt cagctcctca
    19441 tttcagaagt tcgctaccag caacaaagcg agcaaaagga gtggctcttg tttgtggacc
    19501 aacttgaggt agaattagac cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca
    19561 tgaagcaaga tggcaaggac atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa
    19621 ccgatgctag tggacggggg tatcagccta tggtttatgg cctcaaatca gctcagatta
    19681 cagaggacaa tcaactggtt cattttcgtt tccagtttca aaaaggctta gaaagggagt
    19741 tcatctatcg tgtggaaaaa gaagaaagtt aaggcaggtg ttctcctcta tgcagtcacc
    19801 atggcagcta tctttagtct tttgttgcaa ttttacttga accgacaagt cgcccactat
    19861 caagactatg ctttgaataa agaaaaattg gttgcttttg ccatggctaa acgaaccaag
    19921 gataaagccg agcaagaaag tggggaacag gtctttaatc taggtcaggt aagctatcaa
    19981 aacaagaaaa caagcttggt gacgactgtt cgtacgtcta agagccaata tgagtttctg
    20041 tttccttcag tcaaaatcaa agaagagaaa agagataaaa aggaagaggt agcgaccgat
    20101 tcaagcgaaa aagtggagaa gaaaaaatca gaagagaagc ctgaaaagaa agagaattcc
    20161 tagtcaattc aactataatg cgttgaatca agaatagtcc actatagttt ctagaaaatt
    20221 gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag tttactatac
    20281 tttgtgctaa attaaagata tgaaacatga ttttaaccac aaagcagaaa ctttcgattc
    20341 ccctaaaaat atcttcctcg caaacttggt atgtcaagca gccgagaaac agattgatct
    20401 tctatcagac aaagaaattt tagatttcgg tggtgacacg ggtctattag ccttgcccct
    20461 agcccctagc caagcaggct aagtcagtca ctcttgtaga catttctgag aaaatgttgg
    20521 agcaagctcg tttgaaagtg gagcagcaag caatcaagaa tatccagttt ttggagcaag
    20581 atttaccgaa aaatcccttg gagaaagagt ttgattgcct tgctgttagt cgggttcttc
    20641 atcatatgcc tgatttggat gcggctctct cactgtttca tcaacatttg aagtaagatg
    20701 ggaaactcat cattgctgat tttaccaaga cagaagctaa tcatcatgga tttgatttag
    20761 ctgaactgga aaacaagcta attgagcatg gtttttcatc tgtgcatagt cagattctct
    20821 atagcgctga agacttgttt caaggaaatc actcagaatt ctttttaata gtagcccaaa
    20881 aatcactcgc ctagtcaggg agtgattttt ctataaggat ggaaaaaaga agggaaattt
    20941 gataagatag gaatatggat tttgaaaaaa ttgaacaagc ttatacctat ttactagaga
    21001 atgtccaagt catccaaagt gatttggcga ccaactttta tgacgccttg gtggagcaaa
    21061 acagcatcta tctggatggt gaaactgagc taaaccaggt caaagacaac aatcaggccc
    21121 ttaagcattt agcactacgc aaagaagaat ggctcaagac ctaccagttt ctcttgatga
    21181 aggctgggca aacagaaccc ttgcaggcca atcaccagtt tacaccggat gctattgctt
    21241 tacttttggt gtttattgtg gaagagctgt ttaaagagga ggaaattact atcctcgaaa
    21301 tgggttctgg gatgggaatt ttgggcgcta ctttcttgac ctcgcttact aaaaaggtgg
    21361 attatttggg aatggaagtg gatgatttgc tgattgattt ggcagctagc atggcagatg
    21421 taattggttt gcaggctggc tttgtccaag gagatgccgt tcgtccacaa atgctcaaag
    21481 aaagtgatgt ggtcatcagc gacttgcctg ttggctatta tcctgatgat gccgttgcgt
    21541 cgcgccatca agttgcttct agtcaagaac atacttacgc ccatcacttg ctcatggaac
    21601 aaggacttaa gtacctcaag tcagacggat acgctatttt tctagctccg agtgatttgt
    21661 tgaccagtcc tcaaagtaat ttgttgaaag tctggttgaa agaggaggca agtctggttg
    21721 ctatgattag tttacctgaa aatctctttg ctaatgctaa acaatctaag actattttta
    21781 tcctacagaa gaaaagtgaa atagcagtag agccttttgt ttatccactt gctagcttgc
    21841 aagatgcaag tgttttaatg aaatttaaag aaaattttca aaaatggact caaggtactg
    21901 aaatataaaa tagattttgt tataatagtt gaaaacgctt aaaaaggggt atcatgttat
    21961 gacaaaaaca attgcaatca atgcaggaag ttcaagtttg aaatggcaat tatacttaat
    22021 gccagaagaa aaagtattgg cgaaaggttt gattgaacgt atcggtttga aagattcaat
    22081 ttcaactgta aaatttgacg gccgttctga acaacaaatt ttggatattg aaaatcatac
    22141 acaagctgtt aaaattttat tggatgactt gattcgtttc gatattatca aggcttatga
    22201 cgagattaca ggtgttggac atcgtgttgt tgctggtgga gaatatttca aagaatcaac
    22261 agttgttgag ggagatgttt tagaaaaagt tgaagagttg agtttgttgg ctcctctaca
    22321 caacccggca aatgcagcag gtgttcgtgc cttcaaggaa ttgttgccag acattaccag
    22381 tgtagttgtt tttgatactt ccttccacac aagtatgcca gagaaagctt atcgctaccc
    22441 tctaccaaca aaatattaca cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag
    22501 tcaccagttt gtagcaggag aagctgcaaa actcttggga cgtccattag aagacttgaa
    22561 gttaattacc tgtcatattg gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc
    22621 tgtagacact tctatggggt tcactcctct tggtggtatt atgatgggaa cgcgtacagg
    22681 ggatattgat ccagctatca ttccttattt aatgcaatat acagaggatt ttaacacacc
    22741 agaagatatc agtcgtgttc ttaaccgtga atcaggtctt ttgggagttt ctgctaattc
    22801 tagcgatatg cgcgatatag aagcagctgt agcagaaggg aatcacgagg ctagcttggc
    22861 ttatgaaatg tatgttgacc gtatccaaaa acatatcggt cagtaccttg cagtgctaaa
    22921 tggagcagat gccattgttt tcacagcagg tgtcggtgaa aatgcagaga gtttccgtcg
    22981 tgatgtaatc tcagggattt cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt
    23041 tggcgttaca ggagacatct caacagaggc agctaaaatc cgtgtcttgg ttattccaac
    23101 agatgaagaa ttagtcattg cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa
    23161 aaaatattca atacaaggag ttgggaaagt tatttttcca gcttcttttt ctgatgaaat
    23221 tgtccaaaac cttgctatga ttggcttttt tgaaaaatat ggtataatag tagtaattta
    23281 atagatggag ttgagttttg aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg
    23341 cgattttcaa ggaggggaca agttttgcta atcgcaaatt tgtggtctac caattagaaa
    23401 accagaaaaa ccattttcga gtaggtctat cagttagcaa aaaactgggg aatgccgtca
    23461 ctagaaatca aattaagcga cggattcggc atattatcca gaatgcaaaa gggagtctgg
    23521 tagaagatgt cgactttgtt gtcattgctc gaaaaggagt cgaaaccttg ggatacgcag
    23581 agatggagaa aaatctactc catgtattaa aattatcaaa gatttaccgg gaaggaaatg
    23641 ggagtgaaaa agaaactaaa gttgactagt ttgctaggac tgtctctgtt aatcatgaca
    23701 gcctgtgcga ctaatggggt aactagcgat attacagccg aatcggctga tttttggagt
    23761 aaattggttt acttctttgc ggaaatcatt cgctttttat cgtttgatat tagtatcgga
    23821 gtggggatta ttctctttac ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg
    23881 caaatggtgg cttctaggaa aatgcaggaa gctcagccac gcattaaggc gcttcgagaa
    23941 caatatccag gtcgagatat ggaaagcaga accaaactag agcaggaaat gcgtaaagta
    24001 tttaaagaaa tgggtgtcag acagtcagac tctctttggc cgattttgat tcagatgccg
    24061 gttattttgg ccctgttcca agccctatca agagttgact ttttaaagac aggtcatttc
    24121 ttatggatta accttggtag tgtggataca acccttgttc ttccgatttt agcagcagta
    24181 ttcacctttt taagtacttg gttgtccaac aaagctttgt ctgagcgaaa tggcgctacg
    24241 actgcgatga tgtatgggat tccagtcttg atttttatct ttgcagttta tgcgccaggt
    24301 ggagtcgccc tatactggac agtgtctaat gcttatcaag tcttgcaaac ctatttcttg
    24361 aataatccat tcaagattat cgcagagcgc gaggccgtag tacaggcaca aaaagatttg
    24421 gaaaatagaa aaagaaaagc caagaaaaag gctcagaaaa cgaaataaat aaggaggaat
    24481 ctggtaatgg tagtatttac aggttcaact gttgaagaag caatccagaa aggattgaaa
    24541 gaattagata ttccaagaat gaaggctcat atcaaagtca tttctaggga gaaaaaaggc
    24601 tttcttggtc tatttggtaa aaaaccagcc caagtggata ttgaagcgat tagtgaaacg
    24661 actgttgtca aagcaaatca acaggtagta aaaggcgttc cgaaaaaaat caatgatttg
    24721 aacgagcctg tgaagacggt tagtgaagaa accgttgacc ttggtcatgt ggttgatgct
    24781 attaaaaaaa tagaggaaga aggtcaaggt atttctgatg aagtcaaggc tgaaatctta
    24841 aaacatgaaa gacatgccag cactatctta gaagaaactg gtcacattga gattttaaat
    24901 gaacttcaaa tcgaggaagc gatgagggaa gaagcaggcg ctgatgacct tgaaactgag
    24961 caagatcaaa ctgaaaatca agacttgaaa gagatgggct tgaaggtcga gcaaagttat
    25021 gatattgccc aggtggctac ggatgtgact gcctatgttc aagcgattgt ggatgacatg
    25081 gatgttgaag ctacactttc aaatgattat aaccgtcgta gcatcaatct acaaattgac
    25141 accaacgaac caggtcgtat tatcggctac catggtaaag tcttgaaggc cttgcaactg
    25201 ttggctcaaa attatcttta caaccgctat tccagaacct tctacgttac aatcaatgtc
    25261 aatgattatg tcgaacaccg tgcagaagtc ttgcagacct atgcgcaaaa attggcgact
    25321 cgtgttttgg aagaagggcg cagtcataaa acagatccaa tgtcaaatag cgaacgcaag
    25381 attatccatc gtattatttc acgtatggat ggcgtgacta gttactctga aggtgatgag
    25441 ccaaatcgct atgttgttgt agatacagaa taagtaaaat caggtttatc ctgatttttt
    25501 gctagttaga ggaggttaaa ctgatgttga ataagataag agactattta gactttgctg
    25561 gtttgcagta ccgtaatcct gataaagcgg gagcagagcg agagaagatg ctggcattcc
    25621 gccacaaagg acaagaggcc cgaaaggctt ttacagaact ggccaaagcc tttcaagcaa
    25681 gccatccaga atggcaactc caacagacta gccagtggat gaatcaggcc cagcgtttga
    25741 gaccacattt ttgggtttat ctacagagag acggacaagt gacagaacct atgatggcct
    25801 tacgtttgta tgggacatct actgactttg gaatttcttt ggaagtcagt ttcatcgaac
    25861 gtaagaagga tgagcaaaca ctgggcaagc aggccaaagt tttagacatt ccaaccgtta
    25921 aagggattta ttatctaacc tactctaatg gtcaaagtca acggtgggag gcgaatgaag
    25981 aaaagcgtcg tactttacgc gagaaggtga gaagtcaaga agttcgaaaa gttttagtga
    26041 aggtagatgt tcctatgaca gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga
    26101 agtcttattc taaaattctt ccctattatc tagctacgag aaaataagat aatttgtaaa
    26161 acatcataaa tcatacagtc caagagtgaa cagtccgctg tgtaattctt ggtctttttg
    26221 tttgcgcttt cgcattatat aataaactta caaaaacaat tcaaaaggag aacaattatg
    26281 gaagtcgttt caagtgttct aaattggttt tctagcaata ttttgcagaa tcccgcattt
    26341 ttcgtaggtt tattggtgtt gataggatat gcacttttga aaaaacctgc ccatgacgtt
    26401 ttttcagggt ttgttaaagc aacagtaggg tatatgttgc ttaacgtggg tgctggtggt
    26461 ttggttacaa cctttcgtcc aatcttagca gctcttaact acaaattcca aattggtgca
    26521 gcggttatcg acccttactt tggacttgct gcagcaaaca acaaaattgc agcagagttt
    26581 ccagattttg ttggaactgc aactacagct ctattgattg gttttggaat aaatatcttg
    26641 ctcgtagctc ttcgaaagat tacgaaggta agaaccctct ttattactgg tcacatcatg
    26701 gtacaacaag ctgcaacagt atctcttatg gttctattct tagtaccaca attgcgcaat
    26761 gcttacggta cagcagcgat tggtatcatc tgtggacttt actgggcagt tagttcaaat
    26821 atgactgttg aggcaactca acgcttgact ggtggtggcg gatttgcgat tggtcaccaa
    26881 cagcaatttg caatctggtt tgtagataaa gtagcaggac gctttggtaa gaaagaagaa
    26941 agtttagaca atcttaaatt acctaagttc ctctcaatct tccacgatac agttgttgca
    27001 tctgctacct tgatgctcgt attcttcgga gccattcttt taatcttggg tccagacatt
    27061 atgtctaata aagaagtcat cacttcagga actctattca atcctgctaa acaagatttc
    27121 tttatgtaca ttatccaaac agcctttacc ttctcagttt acttgttcgt tttgatgcaa
    27181 ggtgtccgaa tgttcgtatc tgagttgaca aacgccttcc aaggtatttc aaacaaattg
    27241 ttgccaggtt cattcccagc ggttgacgtt gcagcttctt atggatttgg ttctccaaat
    27301 gctgtcttgt caggatttac ctttggtttg attggtcaat tgattacaat tgtcttgctc
    27361 atcgtcttta aaaatccgat tcttattatt acaggatttg taccagtgtt ctttgacaat
    27421 gcagccattg cggtctacgc tgataaacgc ggcggatgga aagcggctgt tatcctttcc
    27481 tttatatcag gtgtccttca agttgctcta ggagctcttt gtgtggccct tctcgatttg
    27541 gcatcttatg gtggctacca tggaaatatc gactttgaat tcccatggct tggatttgga
    27601 tatatcttca aataccttgg tattgttggt tatgtacttg tgtgtctctt cttgcttgtt
    27661 attcctcaac ttcaatttgc caaagcaaaa gataaagaga aatattacaa cggtgaagtt
    27721 caagaagaag cttagtatct agaaaaggag aaataaaatg gttaaagtat tagcagcgtg
    27781 cggaaatgga atgggttcat caatggttat caagatgaag gttgaaaatg ctctccgtaa
    27841 gcttaatcaa acagatttta cagtcaattc atgcagtgtc ggtgaagcta aaggtttagc
    27901 agtaggatat gacatcgtaa tcgcttctct tcatttgatt caagaattgg aagggcgaac
    27961 taatgggaag ttaattggtc ttgataactt gatggatgat aaagaaatca ccgaaaaact
    28021 cagtcaagca ctacagtaaa aggttggagg gggctggaca gaaactgaga gttatcgttt
    28081 ctgtccttct ccctctttaa ataaaggagg cagatatgaa tttaaaacaa gctttaattg
    28141 acaatgactc gatccgacta ggtttagagg ctaacaattg gaaagaagca gtcaaggtag
    28201 cagtagatcc cctaattgaa agtggggcaa ttttgccaga gtattacgat gctatcattg
    28261 aatcgactga agagtatggg ccttactata tcttgatgcc aggtatggct atgccccacg
    28321 ctagacctga agctggtgtg caaagtgatg ccttttcatt gattacctta caaaatcctg
    28381 ttgtattttc agatgggaaa gaggtatctg ttttgttggc actagcagca acaagttcaa
    28441 aaattcacac aagtgtagcc attccacaaa ttattgccct gtttgaatta gaagattcta
    28501 ttgcacgttt acaggcttgc cagactaaag aagatgtctt ggctatgatt gaagaatcta
    28561 aggatagccc ttatctcgaa ggattggatt tggaaagtta gaaagaggaa taaagaaatg
    28621 acaaaaagaa tacctaattt acaagttgca ttagaccatt cagacttgca aggagcgatt
    28681 aaagcagctg tttctgttgg tcaggaagta gatattatcg aagctggaac tgtttgcttg
    28741 cttcaagttg gaagtgaact ggctgaagtc ttgcgtagcc ttttcccaga taagattatt
    28801 gtggcagaca caaaatgtgc tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt
    28861 ggagcagact ggatgacttg tatctgttgt gcaaccatcc ctactatgga agcagctcta
    28921 aaggctatca agactgaacg aggagaacga ggcgaaatcc agatcgagct ttatggcgat
    28981 tggacttttg aacaagctca gctttggcta gatgcaggta tctcacaagc tatttatcac
    29041 caatctcgtg atgctcttct tgctggtgaa acttggggtg aaaaagacct taataaggtt
    29101 aaaaaactca ttgacatggg cttccgtgta tctgtaacag gtggtctaga tgtagatact
    29161 ctcaaactct ttgaaggtgt tgatgtcttt acctttatcg caggtcgtgg aattacagag
    29221 gctgcggatc cagcaggagc agcgcgtgcc ttcaaggatg aaatcaaacg aatttggggg
    29281 taaatcatgg tacgtccaat tggaatttat gaaaaggcaa ccccaacaca ctttacttgg
    29341 ctagaacgtt taaattttgc caaggagtta ggctttgatt ttgtcgagat gtctattgac
    29401 gaacgtgacg agcgtttagc aagacttgac tggagtaagg aagaacgctt ggaagttgtc
    29461 aaagcaatct atgaaactgg tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc
    29521 tacccattgg gttcaaaaga tccagttcta gaggaaaaat ctctagaact catgaaaaaa
    29581 tgtatcgaat tagctcaaga cttgggagtt cgtacgattc aattagctgg ttacgatgtt
    29641 tactatgagg aaaagtcacc ccagacacgc caacgtttta tcaaaaattt gagaaaagcc
    29701 tgtgactggg ctgaagaagc tcaggtggta cttgctattg aaattatgga tgatcctttc
    29761 atcagtagca tcgaaaaata tttggctata gaaaaagaga ttgactctcc cttcctcttt
    29821 gtatatccag atattggtaa tgtgtctgca tggcataatg atatctatag tgagttttat
    29881 cttggtcatc atgccatcgc agctctccat ctcaaggata cttatgcagt gacagaaagt
    29941 tcaaagggcc agttccgaga tgtacctttc gggcaaggtt gtgtcaaatg ggaagaagct
    30001 ttcgatattt taaaggaaac caattataat ggacctttcc taatcgaaat gtggtctgaa
    30061 aattgtgaaa cagtagaaga aacacgcgca gccgttcaag aggcgcaagc ttttctctat
    30121 ccactcatta agaaagcagg tttgatgtaa gatgaatcaa gtaatcaatg ctatgcgtaa
    30181 acgagtctgt gatgccaatc aatcattgcc aaaacatgga cttgtcaaat ttacctgggg
    30241 gaatgtatct gaagttaatc gcgaactcgg tgtcattgtt atcaaaccat caggcgtgga
    30301 ttatgacgaa ttgacacctg aaaacatggt agtgactgat ctagatggta agatcctaga
    30361 aggggattta agaccatctt ccgacctccc aactcatgtg caattatata aggcttggtc
    30421 agaaattggt agtgtggttc acacccattc gacagaagct gttggttggg ctcaggcagg
    30481 tcgtgatatt cctttctacg gaacaaccca tgcagattat ttctacggtt caatcccttg
    30541 cgcccgtagt ttgaccaagg acgaagtaga agtggcctat gaaaaagata ctggcctggt
    30601 tatcgtagaa gagtttgaac atcgcggact taacccggtt gaagtaccag gaattgttgt
    30661 acgcaatcac ggtccattca cctggggcaa aaatccagag aatgctgttt atcactctgt
    30721 cgtactagag gaagtatcaa agatgaatcg ctttacagaa caaatcaatc caagagttgg
    30781 acctgctccc cagtacatac tagaaaaaca ctaccaacgt aaacatggac caaatgctta
    30841 ttatggtcaa aagtaagaac gatgaaggag gagaaaaaga taaatttagc tcctcttttt
    30901 acatttgatt tttattgaga gtaaagttgg aattgaagta attttaaaag attttttaga
    30961 aatagcgctt gatatatata tggtaaaata aaaagaattg ctgtgatatc aatagatttg
    31021 ggggattttt taatatggta ctggataagg caagttgtga tttgcttcaa tatttgatgg
    31081 atcaagaaac gtccaaaacg attatggcga tttcgaaaga tttgaaagag tcaagaagga
    31141 aaatttatta tcacattgac aaaatcaatg ctgctctggg tgacgaggcg cttcacatca
    31201 ttagtattcc acgaattggt attcacttaa cggaagagca gagagatgct tgttgtaaac
    31261 tattatcgga agtagattcg tacgattata tcatgagtgc gcatgaacgt atgatgataa
    31321 tgttactatg gataggtatt tctaaagaac gtattacgat tgaaaaattg atagagttaa
    31381 cagaggtatc taggaatact gttctcaatg atttgaatag tattcgttat caactaactt
    31441 tggaacaata tcaggtgatc ttgcaagtga gcaagtcaca gggataccac cttcatgccc
    31501 accctcttaa taaaattcag tatcttcaat cgcttctata tcatattttt atggaagaaa
    31561 atgccacttt tgtatctatt ttagaagata agatgaaaga gaggttagat gatgagtgtt
    31621 tgctttctgt tgaaatgaac caatttttta aggaacaggt tcctttagtt gaacaagatt
    31681 tagggaagaa aataaaccat catgaaataa cttttatgtt gcaggttcta ccttatttgc
    31741 tgttaagctg tcataatgtt gaacagtatc aagaaagaca tcaggatata gagaaagaat
    31801 tttctttgat aagaaaaaga atagagtatc aggtgtctaa gaaattagga gaacggttgt
    31861 ttcaaaagtt tgaaatttct ttgtcaggac ttgaagtttc tcttgtagct gttctcctcc
    31921 tctcctatcg taaagatttg gatattcatg cagaaagtga tgattttcgg caattaaaac
    31981 ttgctttaga agaatttatc tggtattttg aatcacaaat ccgaatggag attgagaaca
    32041 aggatgattt gttacgaaat ttgatgatcc actgtaaagc cttgttattt agaaagactt
    32101 acggtatttt ttctaaaaat cctctaacaa aacaaattcg atccaagtat ggagaattat
    32161 ttttagtcac tagaaaatct gcggaaattt tagaaggagc atggtttatt cggctaacag
    32221 acgatgatat tgcctatttg acgattcata ttggaggatt tttaaaatat acaccatcgt
    32281 ctcaaaaaaa tatgaaaaaa gtttatctcg tttgtgatga aggtgttgcg gtttcgagac
    32341 ttttgctgaa acaatgcaaa ctttattttc caaatgagca aattgacact gtatttacaa
    32401 cagaacaatt taagagtgtg gaagatattg cacaagttga tgtagtgatt actactaatg
    32461 atgatttgga tagcagattt ccgattttaa gggttaatcc tatccttgaa gcagaagata
    32521 ttttgaaaat gctagactat cttaaacaca atatatttcg taataagagc aaaagtttca
    32581 gtgaaaatct ttctagtctt atttcgtctt atattgtaga tagcaagttg gctagtaagt
    32641 tccaagaaga ggttcaaaca cttataaatc aagaaatagt agttcaagct tttttggaag
    32701 atatttgaag gacagtccaa tgatgaacac aaacctgtgt ttttcttggt cttttttagt
    32761 gttttgaagg gtggtatact aatctcaaag ataacaatta tatccaaagg aggcaacata
    32821 tgccaaacgt caaagaaatt acaagagagt catggatttt agccactttc ccagagtggg
    32881 gaacatggtt gaacgaagaa atcgaagaag aagtcgtacc tgaaggcaac tttgccatgt
    32941 ggtggctagg caactgtggt acttggatta agacaccagc tggtgctaac gttgtcatgg
    33001 acctttggtc aaaccgtgga aaatcaacca aaaaagtgaa agatatggtt cgtgggcacc
    33061 aaatggcaaa tatggcaggt gttcgtaagt tgcaaccaaa cttgcgtgtt cagccaatgg
    33121 ttatcgatcc atttgctatc aacgaactag actattactt agtttcacac ttccacagtg
    33181 atcatatcga cccatacaca gctgcagcaa ttctcaacaa tcctaagtta gagcatgtta
    33241 agtttatcgg tccttaccac tgtggacgaa tctgggaagg atggggtgtt ccaaaagaac
    33301 gtatcatcgt tgttaaacca ggtgacacta tcgaattaaa agatatgaag attcatgcag
    33361 tagaatcatt tgaccgtact tgcttggtaa ctctcccagt gaacggtgct gatgagacag
    33421 gcggtgaact tgctggcttg gctgttacag atgaagaaat ggctcaaaag gctgttaact
    33481 atatctttga aacaccaggt ggaaccatct atcatggtgc agattctcac ttctcaaact
    33541 attttgcaaa acatggtaaa gactttaaaa ttgatgttgc tttgaataac tatggtgaaa
    33601 atccggtagg tatccaagac aaaatgacat ctatcgacct tcttcgtatg gcagaaaatc
    33661 tgcgtaccaa agtcattatc ccagttcact atgatatctg gtctaacttc atggcttcta
    33721 ctaatgagat tctagaactt tggaaaatgc gaaaagatcg cttgcaatac gatttccatc
    33781 catttatctg ggaagttggc ggtaagtaca cttatcctca agatcaacac ttagtagaat
    33841 accatcatcc acgtggtttt gatgattgtt ttgaacaaga ctctaacatt caatttaaag
    33901 ctttgctata atataaaaat attctttgga ggttatccgt atgttgcatg atacggataa
    33961 ttttcatata atagtaaaat agaatgtgtg attcaataat cacctcaaat agaaaggaaa
    34021 ttctatgtca aatctatctg ttaatgcaat tcgttttcta ggtattgacg ccattaataa
    34081 agccaactca ggtcatccag gtgtggttat gggagcggct ccgatggctt acagcctctt
    34141 tacaaaacaa cttcatatca atccagctca accaaactgg attaaccgcg accgctttat
    34201 tctttcagca ggtcatggtt caatgctcct ttatgctctt cttcaccttt ctggttttga
    34261 agatgtcagc atggatgaga ttaagagttt ccgtcaatgg ggttcaaaaa caccaggtca
    34321 cccagaattt ggtcatacgg cagggattga tgctacgaca ggtcctctag ggcaagggat
    34381 ttcaactgct actggttttg cccaagcaga acgtttcttg gcagccaaat ataaccgtga
    34441 aggctacaat atctttgacc actatactta cgttatctgt ggagacggag acttgatgga
    34501 aggtgtctca agcgaggcag cttcatacgc aggtttgcaa aaacttgata agttggttgt
    34561 tctttatgat tcaaatgata tcaacttgga tggtgagaca aaggattcct ttacagaaag
    34621 tgttcgtgac cgttacaatg cctacggttg gcatactgcc ttggttgaaa atggaacaga
    34681 cttggaagcc atccatgctg ctatcgaaac agcaaaagct tcaggcaagc catctttgat
    34741 tgaagtgaag acggttattg gatacggttc tccaaacaaa caaggaacta atgctgtaca
    34801 cggcgcccct cttggagcag atgaaactgc atcaactcgt caagccctcg gttgggacta
    34861 cgaaccattt gaaattccag aacaagtata tgctgatttc aaagaacatg ttgcagaccg
    34921 tggcgcatca gcttatcaag cttggactaa attagttgca gattataaag aagctcatcc
    34981 agaactggct gcagaagtag aagccatcat cgacggacgt gatccagtcg aagtgactcc
    35041 agcagacttc ccagctttag aaaatggttt ttctcaagca actcgtaatt caagtcaaga
    35101 tgccttgaat gttgtggcag ctaaattacc aaccttccta ggtggatcag ctgaccttgc
    35161 tcactcaaac atgacttata tcaagacgga tggacttcaa gacgatacca atcgcttgaa
    35221 tcgtaacatt cagtttggtg ttcgtgaatt tgcaatggga acaatcttga acgggatggc
    35281 ccttcatggt ggacttcgtg tatacggtgg aactttcttc gtcttctctg actatgtgaa
    35341 ggcagctgtc cgcttgtcag ccttacaagg acttcctgtg acttatgtct ttacccatga
    35401 ttcaatcgca gttggggaag atggtccgac tcacgaacca gttgagcatt tagcaggtct
    35461 tcgtgctatg ccaaatctaa atgttttccg tccagcagat gcgcgtgaaa cgcaagcagc
    35521 ttggtacctt gcagtgacaa gtgagaaaac accaactgcc cttgtcttga cacgtcaaaa
    35581 cttgactgtt gaagatggaa cagacttcga caaggttgct aaaggtgctt atgttgtata
    35641 tgaaaatgca gccgactttg ataccatctt gattgcgaca ggttcagagg ttaatcttgc
    35701 tgtctcagct gctaaagaat tggctagtca aggcgaaaaa atccgcgtag tcagcatgcc
    35761 atctacagat gtctttgata aacaagatgc agcttacaag gaagaaattc ttccaaatgc
    35821 agtccgccgt cgtgttgcag tcgaaatggg tgcaagtcaa aactggtaca aatatgttgg
    35881 tctcgatggt gccgttctag gtattgatac cttcggagcc tctgccccag caccaaaagt
    35941 attggcagaa tatggcttta ctgtcgaaaa tcttgtaaaa gttgttcgaa atttgaaata
    36001 atcctaaaaa tcagggcgta agctctggtt tttcttacca gaaaagtaag gtacaatctt
    36061 gtaaaagtag ctgaaatttg atatagtagt cctatgtaaa agacaaagga gaaaacaatg
    36121 aatccaaata ttactttttt aatcatgctt gtaggtatga tggccttgat gttctttatg
    36181 caacgttctc aaaagaaaca agctcaaaag cgtatggaaa gcttaaataa actacaaaaa
    36241 ggctatgaag tgattacaat cggtggactt tatggaacag tcgatgaagt agatacggag
    36301 aagggaacaa tagttcttga cgtagatgga gtttacttga cttttgaact agctgctatc
    36361 aagacagtat taccgctgaa agaaacagct tcactagaag gcgcaattga aaaataagac
    36421 gggatcacga actcccgttt tctataaaag aaaggaaatg ggatgaaaaa attagtcttt
    36481 gtctgtctgg gaaatatttg ccgtagccct atggccgagt ttgttatgaa atcaatgaca
    36541 gataactacg aaatccaaag tcgagcaact tcctcttggg aacatggcaa tccgattcat
    36601 aaggggactc agggaatttt tcaagagtat gagattcctt atgacaagaa caagacatcg
    36661 cttcagatta gtaaggaaga ttttgaagcc tttgattata ttatcggaat ggacgcttca
    36721 aatatttctg acttacgtca gatgtgtcca gtagactgtc aagataagat ttactcattt
    36781 tcatctgaaa gtgttccaga cccttggtat acaggagatt ttgaagaaac ctatcgacgt
    36841 gttcaagagg gctgtcaagc ttggttagaa cgtttagaaa aggagagtta aggtggaaaa
    36901 tcttacgaat ttttacgaaa agtatcgtgt ctatctgact cgtccacgtt tagagctttt
    36961 ggcagtagtt accattgttt tctgtgctgt actcgtcttt tttctaaata ttccaggaaa
    37021 aggtgtctta aaactcgata atggaacgat tgtttatgat ggcagtcttg tccgtggtaa
    37081 aatgaatggc caaggtacca ttaccttcca aaatggagac caatatacag gtggcttcaa
    37141 caatggagcc ttcaacggaa aaggtacctt tcaatctaaa gaaggctgga cctacgaagg
    37201 tgattttgta aatggtcagg ctgaaggaaa agggaaacta acaacagaac aagaagtcgt
    37261 ttatgaagga acttttaaac aaggcgtttt tcaacaaaaa taaagcctcc tatcaaagga
    37321 ggtattatta gaatcacaag gtaagcgctt acctgtgaat ccctttcttt ccaaatccct
    37381 cttccaagca agtttgtgaa ataaaaaata tttgaaataa atttcacaaa cttcaaagat
    37441 aaaacttgat aagaaaagaa aatgagaaaa gtttcacaag agtttaaaaa ttctttgtga
    37501 aatgtttatg aaactgttta caaagttgaa ataatgcgtt ataataaact tgtgaaaaaa
    37561 ttaacaaagg atatcgttcc ttgaaagcta tggaggaaaa tatggctgat aaaaaaactg
    37621 tgacaccaga ggaaaagaaa ctcgttgctg aaaaacacgt agatgagttg gttcaaaaag
    37681 ctctagttgc ccttgaagaa atgcgtaaat tggatcaaga acaagttgac tacatcgttg
    37741 ccaaagcatc agtagcagct ttggatgccc acggagaatt ggctttacat gcctttgaag
    37801 aaacaggacg tggtgtattt gaagacaaag caactaagaa cttgtttgct tgtgaacacg
    37861 tagtaaacaa catgcgccac actaagacag ttggcgttat cgaagaagac gatgtaacag
    37921 gattgactct tattgctgaa ccagttggtg ttgtttgtgg tattactcca acaacaaacc
    37981 caacatcaac agcaatcttc aaatcattga tttcattgaa gacacgtaac ccaatcgtct
    38041 ttgccttcca tccatcagca caagaatcat ctgctcatgc agctcgtatc gtccgcgatg
    38101 cagctatcgc agctggtgct cctgaaaact gtgtacagtg gatcactcaa ccatctatgg
    38161 aagcaactag tgcccttatg aaccacgaag gtattgcaac aatccttgca acaggtggta
    38221 atgccatggt taaagccgca tactcatgtg gtaaaccagc tcttggggta ggtgccggaa
    38281 acgttccagc ttatgttgaa aaatcagcaa acattcgtca agcagcacac gatatcgtca
    38341 tgtctaaatc atttgataac ggtatggtct gtgcatctga acaagcagtt atcattgata
    38401 aagaaattta cgatgaattt gtagcagagt tcaaatctta ccacacttac tttgtaaaca
    38461 aaaaagaaaa agctcttctt gaagagttct gcttcggcgt caaagcaaac agcaaaaact
    38521 gtgctggtgc aaaattgaac gctgacatcg ttggtaaacc agcaacttgg attgcagaac
    38581 aagcaggatt tacagttcca gaaggaacaa acattcttgc tgcagaatgt aaagaagttg
    38641 gcgaaaatga gccattgact cgtgaaaaat tgtcaccagt tattgcagtt ttgaaatctg
    38701 aaagccgtga agatggtatt actaaggctc gtcaaatggt tgaatttaac ggtcttggac
    38761 actcagcagc tatccacaca gctgacgaag aattgactaa agaatttggt aaagctgtta
    38821 aagctattcg tgttatctgt aactcacctt ctacttttgg tggtatcggg gacgtttaca
    38881 atgccttctt gccatcattg acacttggat gtggttctta cggacgcaac tcagttgggg
    38941 ataacgttag tgccattaac ctcttgaata tcaaaaaagt cggaagacgg agaaataaca
    39001 tgcaatggat gaaacttcct tcaaaaacat actttgaacg tgattcaatt caataccttc
    39061 aaaaatgtcg tgacgttgaa cgtgtcatga tcgttactga ccatgccatg gtagagcttg
    39121 gtttccttga tcgtatcatc gaacaactgg accttcgtcg caataaggtt gtttaccaaa
    39181 tctttgcgga tgtagaaccg gatccagata tcacaactgt aaaccgtggt actgagatta
    39241 tgcgtgcctt caaaccagat accatcatcg cactcggtgg tgggtctcca atggatgctg
    39301 ccaaagtaat gtggctcttc tacgagcaac cagaagtgga cttccgtgac cttgtccaaa
    39361 aattcatgga tatccgtaaa cgtgccttca agttcccatt gcttggtaag aagactaaat
    39421 tcatcgcgat tccaactaca tctggtacag gatctgaagt aacaccattt gccgttatct
    39481 ctgataaagc aaacaaccgt aaatacccaa tcgctgacta ctcattgaca ccaactgtgg
    39541 caatcgtaga tcctgctttg gtattgacag ttccaggatt tgttgctgct gatactggta
    39601 tggacgtatt gactcacgcg acagaagcat acgtatcaca aatggctagt gactacactg
    39661 atggtttagc acttcaagcc attaaattgg tctttgaaaa tctcgaaagc tcagttaaga
    39721 atgcagactt ccactcacgt gagaaaatgc ataacgcttc aacaatcgct ggtatggcct
    39781 ttgccaatgc cttcctaggt atttctcact caatggccca taagattggt gcgcaattcc
    39841 acacaatcca cggtcgtaca aatgctatct tgcttccata cgttatccgt tacaacggta
    39901 cacgtccagc taagacagca acatggccta agtacaacta ctaccgtgca gatgaaaaat
    39961 accaagatat cgcacgcatg cttggacttc cagcttctac tccagaagaa ggggttgaat
    40021 cttacgcaaa agctgtctac gaactcggtg aacgtattgg gatccaaatg aattttagag
    40081 accaaggaat tgacgaaaaa gaatggaaag aacattctcg tgaattagcc ttcctggctt
    40141 atgaagacca atgttcacca gctaacccac gtcttccaat ggtagaccat atgcaagaaa
    40201 tcatcgaaga tgcatactat ggctacaaag aaagaccagg acgccgtaaa taattgttta
    40261 tcagtctaga agcaagacaa aaactcaatt tgagggaaag atccagtact ttttctatga
    40321 taaaaggcat cctatcaagg tttttgaaca cctgatagga tgccttttta tgatattgag
    40381 gcctttttgc cctttttgaa aaactagaat agaaacaaaa tatataatag attgaaactg
    40441 gaatagtaca cttctgcttc taaaacattg ttagaattcg atttgactgt cctgatcgat
    40501 ttgtcctgtt cttatttcat tttaatatat aaaaaatat
//
LOCUS       DAVBNN010000015        38411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBNN010000015 DAVBNN010000000
VERSION     DAVBNN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.015"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ847_000833"
     CDS             complement(56..1066)
                     /locus_tag="VQ847_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3050194.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ847_000834"
     CDS             1215..2384
                     /locus_tag="VQ847_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3050195.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ847_000835"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ847_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3050196.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ847_000836"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ847_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3050197.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ847_000837"
     CDS             4146..4379
                     /locus_tag="VQ847_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3050198.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VQ847_000838"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VQ847_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4918..5148
                     /gene="blpU"
                     /locus_tag="VQ847_000839"
     CDS             4918..5148
                     /gene="blpU"
                     /locus_tag="VQ847_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3050199.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5863..8016
                     /locus_tag="VQ847_000840"
     CDS             5863..8016
                     /locus_tag="VQ847_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3050200.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8029..9378
                     /locus_tag="VQ847_000841"
     CDS             8029..9378
                     /locus_tag="VQ847_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3050201.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9548..10255
                     /locus_tag="VQ847_000842"
     CDS             9548..10255
                     /locus_tag="VQ847_000842"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3050202.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10457..14182
                     /locus_tag="VQ847_000843"
     CDS             10457..14182
                     /locus_tag="VQ847_000843"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3050203.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14275..15717
                     /locus_tag="VQ847_000844"
     CDS             14275..15717
                     /locus_tag="VQ847_000844"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3050204.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15754..16776
                     /locus_tag="VQ847_000845"
     CDS             15754..16776
                     /locus_tag="VQ847_000845"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3050205.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16773..17318
                     /gene="purN"
                     /locus_tag="VQ847_000846"
     CDS             16773..17318
                     /gene="purN"
                     /locus_tag="VQ847_000846"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3050206.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            17402..17911
                     /locus_tag="VQ847_000847"
     CDS             17402..17911
                     /locus_tag="VQ847_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3050207.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17936..19483
                     /gene="purH"
                     /locus_tag="VQ847_000848"
     CDS             17936..19483
                     /gene="purH"
                     /locus_tag="VQ847_000848"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3050208.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19605..20867
                     /gene="purD"
                     /locus_tag="VQ847_000849"
     CDS             19605..20867
                     /gene="purD"
                     /locus_tag="VQ847_000849"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3050209.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21270..21758
                     /gene="purE"
                     /locus_tag="VQ847_000850"
     CDS             21270..21758
                     /gene="purE"
                     /locus_tag="VQ847_000850"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3050210.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            21745..22836
                     /gene="purK"
                     /locus_tag="VQ847_000851"
     CDS             21745..22836
                     /gene="purK"
                     /locus_tag="VQ847_000851"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3050211.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            22846..23073
                     /locus_tag="VQ847_000852"
     CDS             22846..23073
                     /locus_tag="VQ847_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3050212.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23136..24434
                     /gene="purB"
                     /locus_tag="VQ847_000853"
     CDS             23136..24434
                     /gene="purB"
                     /locus_tag="VQ847_000853"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3050213.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ847_000854"
     CDS             complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ847_000854"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3050214.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28740..29456)
                     /locus_tag="VQ847_000855"
     CDS             complement(28740..29456)
                     /locus_tag="VQ847_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3050215.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29804..31591
                     /locus_tag="VQ847_000856"
     CDS             29804..31591
                     /locus_tag="VQ847_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3050216.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31588..32064
                     /locus_tag="VQ847_000857"
     CDS             31588..32064
                     /locus_tag="VQ847_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3050217.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32092..32997
                     /locus_tag="VQ847_000858"
     CDS             32092..32997
                     /locus_tag="VQ847_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3050218.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32984..33799
                     /locus_tag="VQ847_000859"
     CDS             32984..33799
                     /locus_tag="VQ847_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3050219.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33806..34210
                     /locus_tag="VQ847_000860"
     CDS             33806..34210
                     /locus_tag="VQ847_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3050220.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34509..35675
                     /locus_tag="VQ847_000861"
     CDS             34509..35675
                     /locus_tag="VQ847_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3050221.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35791..36828
                     /locus_tag="VQ847_000862"
     CDS             35791..36828
                     /locus_tag="VQ847_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3050222.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37035..37889
                     /locus_tag="VQ847_000863"
     CDS             37035..37889
                     /locus_tag="VQ847_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3050223.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            38039..38279
                     /locus_tag="VQ847_000864"
                     /pseudo
     CDS             38039..38279
                     /locus_tag="VQ847_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT        10750 a         7406 c         9116 g        11139 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagatagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggcattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag caagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccag
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaag aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ctagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggt ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga gaccttggca gctgttttac
     1801 gcaagtatga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccagac tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct gggcttatgt cgactttgcc gactgtagat
     3541 gggaagggat ttgacatgct agacctcggt gccaatgcgg aaaatacagc ccagcacctc
     3601 catcaatacg cggttctagg atccttctat gctaaaaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggct tgctcaataa cggaacagag agtagcaagg gcgatccgct tcgtaaggaa
     3721 acttatgaat tactagtggc tgatgaaagt ttgaacttta tcggaaatgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacaac tcaattattc agatattggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aagaaattga ccaactccaa aacgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaatc
     4561 atgcgctatc taaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta
     4621 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     4681 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt ctatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agcagtacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta
     5161 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
     5221 gaaaaaaatt tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa
     5281 aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaatagg agtcttatag
     5341 taacgagtca aaaaaggagt aactatgaat cgtaatttag aacggtgtta tctattctga
     5401 ctaggaatag atcataccag aggtagctta gaaatagcag agacattaga aattgaagta
     5461 ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc ttgtctaggg
     5521 tgacagtaaa aaatcaattt cctttcaata gcatattttt agtgggcagt actcttgttc
     5581 tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt tgggaaggaa
     5641 gtccagtttt tgtttagtga ttggggtaag atagttgtta tcagatgagt ttatactctt
     5701 cgaaaatcaa attcaaacca cgtcaacgtc gccttgccgt atatatgtga ctgacttcgt
     5761 cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt
     5821 gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt tgggaaacgt
     5881 cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc catggttttt
     5941 ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa gacgaccatg
     6001 gatgggacga cggctttggg cttggtcaag gtggcagagg agattggttt tgagacgcga
     6061 gccattaagg cggatatgac gctttttgac ttgccggatt tgacttttcc ttttgttgcc
     6121 catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca ggataaggat
     6181 agcattcata ttgccgatcc agatcccggg gtgaagttga ctaaactgcc acgtgagcgt
     6241 tttgaggaag aatggacagg agtgactctt tttatggcac ctagtccaga ctataagcct
     6301 tataaggaac aaaaaaatgg tctgctctct tttatcccta tattagtgaa gcagcgtggc
     6361 ttgattgcca atatcgtttt ggcaacactc ttggtaaccg ggattaacat tgtgggttct
     6421 tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc gacactaggg
     6481 attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc ttacgctcag
     6541 gagtatctct tgcttgtttt ggggcaacgc ttgtcgattg acgtgatttt gtcctatatc
     6601 aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg ggagatcgtg
     6661 tctcgtttta cagatgctaa cagtatcatc gatgcgctgg cttcgaccat cctttcgatt
     6721 ttcctagatg tgtcaacggt tgtcattatt tcccttgttc tattttcaca aaataccaat
     6781 ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt tgcctttatg
     6841 aagccgtttg aaaagatgaa tcgggatacc atggaagcca atgcggttct gtcttcttct
     6901 atcattgagg acatcaacgg tattgagact atcaagtcct tgaccagtga aagtcagcgt
     6961 taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac ctatagtcga
     7021 gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa tgtcggcatt
     7081 ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca gttgattacc
     7141 tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa tctgcaaacc
     7201 aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct agtagcttct
     7261 gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga gatgaccttc
     7321 aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat caatttaacc
     7381 gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa gacgactttg
     7441 gccaagatga tggttaattt ttacgaccca agtcaagggg agattagtct gggtggtgtc
     7501 aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct gcctcaacag
     7561 ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa ggaggggacg
     7621 acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga tatcgagcgc
     7681 atgccactga attaccagac agaattgact tcggatgggg cagggatttc aggtggtcaa
     7741 cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt gattttggat
     7801 gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa tctcatggct
     7861 ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg gacagagaag
     7921 gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga tttgcttgca
     7981 cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat gaaaccagaa
     8041 tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag tagtgtgatt
     8101 gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc agagaaggag
     8161 atgagtttgt ccactagagc tactgtcgaa cctagtcgta ttcttgcaaa tatccagtca
     8221 actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt taagaagggg
     8281 gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc ctatgccagt
     8341 cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa gagcctgcaa
     8401 gaaggggaga accactttcc agaggaggat aagtttggct accaagccac ctttcgcgac
     8461 tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga gaccatcgcg
     8521 tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat cagtcaaaca
     8581 gaggctaaaa ttcgcgatta ccagacagct aagtcagcta ttgaaacagg tgcttccttg
     8641 gccggtcaga atctagccta ctctttttac cagtcctaca agtctcaggg cgaggaaaat
     8701 ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca gttagaatct
     8761 agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc ctatgcgtca
     8821 gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt tggtcaggaa
     8881 ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt acagggaaat
     8941 cttttagaca aggggaaaat tacggcgagt gaggatgggg tgcttcatct taatcctgag
     9001 accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta tccatctttg
     9061 gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt agcaagaatc
     9121 aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca acttttccta
     9181 gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg gaatttcttt
     9241 aaaatcgagg cggagactaa tctaacttcg gagcaggctg aaaaacttag gtacggggtg
     9301 gaaggccgct tgcagatgat tacgggcaag aaaagttatc tacgttatta tttggatcaa
     9361 tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa actgtgagaa
     9421 agattcttct tgcagttttt tctttacaat ttttgaaaaa tatctactat ttattcggtt
     9481 aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac gaaaggcgaa
     9541 ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct atacaactga
     9601 ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca atggtgtcaa
     9661 gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt ttatttttga
     9721 gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag acacggaaca
     9781 actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact atactgctgg
     9841 ttccttttca aaacgttttg gtgtggatga aggaatcgcc ttggagactc cgattgtcga
     9901 attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc atgtgaaatt
     9961 cctacagatt gcggatgacc agcagattgc ctacttgaag gaagaaacgc gtcgtatcaa
    10021 tgaactattg aaagtctggt ttgctgagat tgggcttaaa ttgattgact ttaagctaga
    10081 gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac cagataactg
    10141 ccgcttgtgg gatgctgatg gcaaccacat ggataaggat gttttccgta gaggattggg
    10201 agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga aataatctgt
    10261 ttgcaatgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag gtcccccaga
    10321 ccttttcact ctgtagagaa ctaggtgaac taaccgatgt ttacgaaatt gtctaggaaa
    10381 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
    10441 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
    10501 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
    10561 tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt ttgcacctgc
    10621 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
    10681 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
    10741 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
    10801 caacacagcc caactttact tggtgaataa agatattgat gtgactgagt tggaagctgt
    10861 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga cagggattgc
    10921 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct ttgaaagcta
    10981 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
    11041 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
    11101 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
    11161 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
    11221 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
    11281 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
    11341 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
    11401 ttggctcctc atgtttaaaa atgaaaccca caaccatcca acagaaattg agccatttgg
    11461 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
    11521 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
    11581 tgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt attcttcata
    11641 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
    11701 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
    11761 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag gtcgtgatgg
    11821 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
    11881 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
    11941 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gcgtctgtgt
    12001 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
    12061 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
    12121 ggttcgtcct gaagatgtgg atgccttcgt tgccgaatgt aacaaagaaa atattgatgc
    12181 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgaactgga atggtgagac
    12241 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
    12301 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
    12361 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
    12421 gactgtcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
    12481 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
    12541 tactgcgtcg gtcattgctc aaggtttcaa ctcatatgta gctgaatggt ctccatacca
    12601 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
    12661 gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc aagcagagcg
    12721 ttttggtcag ccagtagccg cccttctagg ctctattgaa gctcagattc aacttggctt
    12781 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
    12841 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
    12901 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
    12961 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
    13021 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
    13081 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
    13141 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
    13201 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
    13261 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
    13321 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
    13381 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
    13441 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
    13501 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
    13561 ctttgccggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
    13621 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggctt
    13681 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccatacgg
    13741 aaactttgaa gatgctaaca gtactagtcc aaccctcttc tacaatgatg ccaaccaaca
    13801 cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt tggctggtgt
    13861 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
    13921 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
    13981 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
    14041 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
    14101 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
    14161 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
    14221 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
    14281 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
    14341 gctgctaagt tgacctactt tggactccac agtcttcaac accgtggtca ggagggggca
    14401 ggaatcctct ccaacgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
    14461 gaagttttca gaaatccatc taatttggat aaattgacag gagctggtgc gattgggcat
    14521 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt cctcttccgt
    14581 tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc agcctctctc
    14641 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
    14701 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
    14761 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    14821 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    14881 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg tgatttgaag
    14941 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    15001 acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga ttctaatatc
    15061 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    15121 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    15181 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    15241 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    15301 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    15361 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    15421 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    15481 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    15541 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    15601 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    15661 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    15721 acagattctc cattaaagaa aaggaaaaaa taaatgacaa ataaaaatgc atatgcccag
    15781 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    15841 cgtacggaga gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgatctt
    15901 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    15961 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    16021 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    16081 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    16141 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    16201 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    16261 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    16321 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    16381 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    16441 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    16501 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    16561 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    16621 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    16681 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    16741 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    16801 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    16861 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    16921 ttgaactcaa ggagtttgag agcaaggcag actacgaagc agcccttgtc gaactcttgg
    16981 aagaacacca gattgacttg gtttgcctag caggctacat aaaaatcgtt ggaccaacct
    17041 tattgtcggc ttatgaaggt cggattgtca atattcatcc agcctacttg ccagaatttc
    17101 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    17161 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    17221 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    17281 tgtatctgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    17341 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    17401 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    17461 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    17521 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    17581 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    17641 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    17701 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    17761 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    17821 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    17881 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    17941 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    18001 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    18061 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    18121 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    18181 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    18241 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    18301 tatcgatatt ggtgggccat ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    18361 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    18421 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    18481 tgacgccttg attgcaaaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    18541 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    18601 ggacttttac cagaaagctt tgcctacaga ttactccatt gcttcagcca aacagctcaa
    18661 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    18721 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    18781 tcaagctgat gacatcgaga ctgcttggga atacgcttat gagtctgacc cagtgtctat
    18841 ctttggtgga attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    18901 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagccatttt
    18961 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    19021 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    19081 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    19141 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggcattat
    19201 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    19261 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    19321 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    19381 catccagccc ggtggctcag tccgtgacca agaatctatc gaagccgctg acaagtatgg
    19441 cttgaccatg gtcttcacag gagtgagaca ttttagacat taagaagata aaagggaaga
    19501 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    19561 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    19621 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    19681 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    19741 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    19801 ggacctttat cggcccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    19861 ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    19921 ttgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag
    19981 attttgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    20041 atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    20101 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    20161 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    20221 acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa gggcctaaca
    20281 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    20341 cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc
    20401 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc atcgagttca
    20461 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    20521 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcacgtgg acggacaagg
    20581 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagattat tcaaagggtg
    20641 ttgagttgcc agtcaaaacc gatggtgaca tcattaccta ctatgcaggg gctaagtttg
    20701 cggaaaatag cagagcgctg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    20761 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    20821 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    20881 acgcgacgca gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    20941 tgttctggtc agggggaaac tttgagacct taggctcaaa gtttaggaat gaaaccgaag
    21001 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    21061 atacgttaat ggtcgtatgg tttgcgagcg ttagcgagct aatatggagc aattaccgcc
    21121 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    21181 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    21241 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    21301 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    21361 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    21421 aagaagcccg tagccgtggc atcaagatca tcatcgcagg tgctggtggc gcagcccatt
    21481 tgccaggtat ggtcgctgct aaaacaatcc ttccagtcat tggtgtgcca gtcaactctc
    21541 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    21601 ttgcgaccat ggctatcggt gaagcaggtg cgacaaatgc ggccctcttc gctctccgtc
    21661 tcctctcagt agaggatcag tctatcgcga cagcattggc agatttcgca gaagaacaag
    21721 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    21781 ggtcaactgg gtcagatgat ggccatttct gctatctaca tggggcacaa ggttatcgcg
    21841 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    21901 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    21961 gaaaatgtcg acgctgacgg tttggatgtc gttatcaagg atggacaact ccctcaagga
    22021 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    22081 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    22141 gacttgtcga aaaactatgt ccttaagatc gcaacaggtg gttatgatgg acacgggcaa
    22201 aatgtcattc gttcagcaga cgatttggaa gaagcctatg cattagccga ctcagcagct
    22261 tgtgtcttgg aagaatttgt caattttgac cttgagattt ctgtcatcgt gtcaggaaat
    22321 gggaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    22381 aagaccatcg taccagcccg tatttctgaa agtctagcag acaaggctaa agctatggca
    22441 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgaca
    22501 gctgatgaca tcattgtcaa tgagattgct ccacgaccac acaactcagg ccactactct
    22561 attgaagcct gtgacttttc acaatttgac acgcatatat taggtgttct gggagcacca
    22621 ttgccagcca tcaaactaca tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt
    22681 gaggccgctg aaaaatatgt cacagaaaat ccaagcaccc acctccacat gtatggtaaa
    22741 atagaagcaa agcataatcg taagatggga catgtgactt tgtttagtga tgtaccggat
    22801 agtgtggaag agtttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    22861 gttaatgcat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgctagt
    22921 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    22981 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    23041 tctgtgttta ttggaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    23101 tcccaacagc ttaagaagaa aggaaagatt aacacatgat caaccgttac tctcgccctg
    23161 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    23221 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    23281 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    23341 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    23401 actatgggtt aacttctacc gacgtggtgg atactgccta tggttacctc tacaagcagg
    23461 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    23521 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    23581 cttttggtct taaattggca acttggtata gcgaaatgaa acgcaatatc gagcgcttcg
    23641 agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    23701 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    23761 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    23821 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    23881 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    23941 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    24001 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    24061 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    24121 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    24181 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    24241 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    24301 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    24361 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    24421 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    24481 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    24541 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    24601 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    24661 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    24721 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    24781 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    24841 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    24901 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    24961 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    25021 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    25081 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    25141 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    25201 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    25261 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    25321 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    25381 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    25441 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    25501 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtactcagcg
    25561 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    25621 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    25681 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    25741 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    25801 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    25861 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    25921 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    25981 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    26041 gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct
    26101 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    26161 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    26221 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    26281 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    26341 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    26401 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    26461 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    26521 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttcttttaga
    26581 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    26641 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    26701 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    26761 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    26821 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    26881 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    26941 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    27001 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    27061 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    27121 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    27181 ttaaaagcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    27241 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    27301 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    27361 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    27421 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    27481 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    27541 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    27601 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    27661 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    27721 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    27781 tagccataat gtttcgcttt atcgatgatt tccttgagtt gttctggtga gaaatattta
    27841 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    27901 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    27961 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    28021 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    28081 gtttgagtta ccacctctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    28141 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    28201 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    28261 tgaggggaat cagaaactgt atggatggtc ggttggtttt ctgtagtagt agtaactcca
    28321 tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc tgctcctaca
    28381 gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa acctcctgat
    28441 tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt tcttatatta
    28501 acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata taaaatttaa
    28561 gcttaagatt tcagattggt cggaaaaaat acgtatatat atctagtata atttttggtt
    28621 ctatttctat aaaatattcc acaaattata gaatcttcca aaaataggta agcgctacct
    28681 ttttggtgtg gtataataag catagaaaaa gcccgagcga ttaggctcag gctttcttct
    28741 tagtgatcac ggtcacatga gatgaattta atcttgtagt aatcagatcg tttgtaagtt
    28801 tcactgtatt ctaaaacttg gccagttgat tcgagtttgg tgattttagt ttgtaggaca
    28861 gtagggaatt gttcatcgac tccgaggact gaagccgcat gttctggagt tggaaagact
    28921 atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa tgtggtagtc taacttgaaa
    28981 cgattataga tagaactata gtattcaagg tttggataat ttgcgttgat atattgttct
    29041 gggatgtagg atgtatggta gatataaacg acaccgtttg attcgcggat acgttcaatc
    29101 ttgtagtaga attgatcgcc gcgtagaccc aatttttcca ggtaaacaag cttgtttccg
    29161 cgttcaattg aaagaacagt taccttatca tctttagcat tgaagagttc aatatctgaa
    29221 aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg ttccttttcc ttgttggcgg
    29281 acaatatagc catctttggc aaggtcgttt aaggcgcgaa caactgtgat agagctgaca
    29341 tcgtacattg aaatgagttc tgcttcagta taaaatttat ctccactgct aaactgccca
    29401 gagatgattt tattttttaa ttcgtctttt atgtattgat atttgggaat tgccatattt
    29461 ttacctctat tttccttctc catagaaaat tttaccataa aagcgaaaaa aatagtagtc
    29521 ttttgaataa aaaattagaa taatagtttg aaaaattaag ctatataggg attgatcata
    29581 ttttataaat gtattctata caaaattatt ttaggtccta tattccaaat ttaaagagcg
    29641 tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt gtgtataata gtaaaaatgc
    29701 agtaaatatc ccgacaattt ctattgacag ttcaaacaga ttggtttata attaatataa
    29761 caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt tttatgacac gatttgagat
    29821 acgagatgat ttctatctcg atggaaaatc atttaagatt ttatctggtg ccattcatta
    29881 ttttagggtt cctccagagg attggtatca ttcgctctat aacttgaagg ctcttggttt
    29941 taatacggta gagacttatg ttgcttggaa tttacacgag cctcgtgaag gtgagtttca
    30001 ttttgaaggt gatctggatt tagagaaatt tctccaaata gcgcaggatt tgggtctcta
    30061 cgcaattgtg cgtccgtctc catttatctg tgcggaatgg gaattcggtg gcttaccagc
    30121 ttggctcttg accaagaaca tgcgaattcg ctcatctgac ccagcatata tcgaggcagt
    30181 tggtcgctac tatgatcagt tattgccaag actggtgcct cgtttgttgg acaatggtgg
    30241 caatattctc atgatgcagg ttgaaaatga gtatggttct tacggagaag ataaggctta
    30301 cctgagagcg attcgacagc taatggaaga gtgtggcgta acctgtcccc tctttacatc
    30361 agatggtcca tggcgagcta ctctgaaagc tggaacctta attgaagagg acctctttgt
    30421 aacaggaaac tttggttcta aggcacctta caacttttcg cagatgcagg aattctttga
    30481 tgaacatggt aagaaatggc cactcatgtg tatggagttc tgggatggtt ggttcaatcg
    30541 ctggaaagaa ccgattatca cacgggatcc taaggaattg gcagatgcag ttcgagaggt
    30601 tttggaacaa ggctctatca atctttacat gttccacggt ggtacaaact ttggtttcat
    30661 gaatggttgc tcagctcgag gaactttgga cctgccacaa gttacgtctt atgattacga
    30721 tgcccttctg gatgaagaag gaaatccaac tgctaaatat cttgcagtca agaagatgat
    30781 ggcaacacat ttttcagagt atccgcagtt ggaaccactc tacaaagaga gtatggagtt
    30841 ggatgctatt ccactagttg aaaaagtttc tttgtttgaa accttagata gcttgtcaag
    30901 tcctgtagaa agtctctatc ctcaaaagat ggaggagctg ggacaaagtt atggctacct
    30961 actttatcga acagaaacaa actgggatgc agaagaagaa agacttcgta tcattgatgg
    31021 tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt aaaactcaat atcagacaga
    31081 gattggggaa gatatttttt atcaaggtaa aaagaaaggg ctatctaggt tagatatctt
    31141 gatagaaaat atggggcgtg tcaactatgg gcataagttc ttagcggata cgcaacgtaa
    31201 gggaattcgg acaggggtct gtaaggatct gcatttctta ctaaactgga aacactatcc
    31261 actcccacta gacaatcctg agaaaattga tttttcaaaa ggatggactc aaggacaacc
    31321 agccttttac gcttatgact ttacagtcga agagccaaaa gatacttacc tagacttgtc
    31381 tgagtttggt aagggggttg cctttgtcaa tgggcagaat ctaggacgtt tttggaacgt
    31441 tggcccaact ctctcacttt atatccctca tagctatctc aaggaaggtg ccaaccgcat
    31501 cattatcttt gaaacagaag gtcaatataa agaagagatt catttaactc gtaaacctac
    31561 actaaaacat ataaaggggg aaaacttatg acaattgtag gatgccgtat tgatggacgt
    31621 ttgatccacg gacaagtagc caatctttgg gctggaaaac taaatgtttc acgcattatg
    31681 gttgtagacg acgaagttgt caacaacgat attgaaaaga gtggtttgaa acttgcgaca
    31741 ccaccaggtg tgaaattgag tattttgcca gttgagaaag ctgcagccaa tattcttgct
    31801 ggcaaatacg atagccaacg tctctttatc gtggctcgta aaccagaccg cttccttggt
    31861 ttggtagaag caggtgtacc acttgaaacc cttaatgttg ggaatatgtc tcaaacacca
    31921 gaaactcgtt ctattacacg ttctatcaac gtagtagaca aggatgtgga agacttccac
    31981 aaactggcag aaaaaggtgt taaacttact gctcagatgg ttccaaatga tccaatttca
    32041 gactttttga gcttattaaa ataggaaaaa aatttttagg aggtcattgt tatgatacaa
    32101 tggtggcaaa ttttacttct cactttgtac tcagcttatc aaatctgtga tgagttgacg
    32161 atcgtttcat ctgcaggttc ccctgtattt gctggtttca ttactggttt aatcatggga
    32221 gatgtgacta ctggtttact tatcggtggt aacttgcaac tgttcgttct tggggttggt
    32281 accttcggtg gtgcttctcg tatcgacgca acttctggtg cggttcttgc gacagccttc
    32341 tctgtttcac aaggaattga tgcaccgctt gccattacta caatcgctgt accagtagca
    32401 gctctcttga cttacttcga cgttcttggt cgtatgacta ctaccttctt cgctcaccgt
    32461 gtggatgctg caatcgaacg ctttgactat aaaggtattg aacgcaacta cttgcttggt
    32521 gcgattccgt gggctctatc tcgtgccctt ccagtcttct ttgcccttgc ttttggtggt
    32581 gcctttgtac aatcagtagt agacttcgtt gaagcctaca aatgggttgc agatggcttg
    32641 acacttgcag gacgtatgct tccaggtctt ggatttgcaa tcttgcttcg ttaccttcca
    32701 gttaaacgta accttcacta ccttgctatg ggatttggtt tgacagctat gttgactgtt
    32761 ctttactcat atgtaacagg tcttggtggc gctgttgctg gtatcgtagg tactcttcct
    32821 gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca aaggtttgtc tatgattggt
    32881 atttctatcg taggtatttt ccttgcagtg cttcacttca aaaatagcca aaaagtagct
    32941 gtagcagcac cttctacacc atcagaaagt ggggaaatcg aagatgacga attctaatta
    33001 caaacttaca aaagaagatt ttaatcaaat caacaaacgt agcttgttta ctttccaatt
    33061 aggttggaac tacgaacgta tgcaagcttc tggttacctt tacatgatct tgcctcagtt
    33121 gcgtaaaatg tatggtgatg gaactcctga attgaaagaa atgatgaaag ttcatactca
    33181 attcttcaat acttcaccat tcttccatac cattatcgct ggttttgacc ttgccatgga
    33241 agaaaaagat ggtgtaggtt caaaagacgc cgttaacggt atcaagacag gtttgatggg
    33301 accattcgct cctcttgggg atacaatctt tggttcactt gtacctgcta tcatggggtc
    33361 agtcgcagca actatggcta tcgctggcca accttggggg atcttccttt ggattgcagt
    33421 tgcagtagcg tatgacatct tccgttggaa acagttggaa tttgcttaca aagaaggggt
    33481 taaccttatc aacaacatgc aaagtacctt gacagctttg attgacgctg catctgtact
    33541 tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt aactttgaaa tttcttacaa
    33601 gttgccaatc ggtgaaaaga tgattgattt ccaagacatc ttgaaccaaa tcttcccacg
    33661 tttgcttcca gcaatcttta ctgcctttat cttctggttg cttggtaaga aaggtatgaa
    33721 ctctactaaa gctatcggta ttattatcgt acttgctttg gctctttctg cccttggtca
    33781 ctttgcactt ggaatgtaat tccttatgac taaatcatta attttggtga gccatggtcg
    33841 cttctgtgag gagcttagag gtagcacaga aatgattatg ggcccacaag acaacattta
    33901 cacagtagct cttcttccag aagatggccc agaagaattt actgctaaat ttgaagctgt
    33961 tattgaagga ttggatgatt tcctagtctt tgcggatctt ctcggtggga caccttgtaa
    34021 tgtggtgagt cgcttgatca tggaaggtcg tgatattgac ctttacgcag ggatgaatct
    34081 tccaatggtg attgaattta tcaatgcgag ccttacaggc gcagatgcgg actacaagag
    34141 ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta gcgggcttcg atgatgacga
    34201 agatgaataa tactcttcga aaatctcttc aaactacgtc aacgtcgcct tgccgtaggt
    34261 atatgttact gacttcgtca gtcttatccg gcaacctcaa aacggtgttt tgagctgact
    34321 tcgtcagtct tatccggcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    34381 acagatttta gttggaactc gattcaattc atgtgacaac gtgaaaatcg ttagagcatt
    34441 ttatatagaa tatacatggg aatgtagctt actcccattc ccatatttaa tagaaaaaga
    34501 ggaactcaat gctacattat acaaaagaag acttgctcga attgggtgca gaaatcacta
    34561 cgcgtgaaat ctaccaacag cctgatgtat ggagagaagc ttttgaattt tatcaagcaa
    34621 aacgtgaaga aattgcagcc ttcctacaag aaatcgctga taaacatgac tatattaagg
    34681 ttatcttgac aggtgctggg acttctgctt atgtgggaga taccttgcta ccttatttta
    34741 aggaagtcta tgacgaacgc aaatggaatt tcaatgctat tgcgacaaca gatatcgttg
    34801 ccaatccagc aacctatttg aaaaaagatg tggcaactgt ccttgtgtct tttgctcgta
    34861 gtgggaactc gcctgaaagt gtggcgactg ttgatttggc caaatccttg gtggatgagc
    34921 tttatcaagt gacgattact tgtgcagcag atggtaaatt ggctcttcaa gctcacggtg
    34981 atgaccgtaa tctcttgctc ttgcaaccag ctgtctctaa tgatgctgga tttgccatga
    35041 cttctagctt tacgtctatg atgttgacag ctctcttggt ctttgatcct acagaatttg
    35101 ctgttaagtc tgaacgtttt gaagttgtat ctagtcttgc ccgtaaagtt ttagacaagg
    35161 cagaagatgt caaagagctt gttgatttag actttaaccg tgtcatctat ctaggcgctg
    35221 gtcctttctt tggacttgct catgaagctc agctcaagat tttggaatta actgctggtc
    35281 aagttgcgac catgtatgaa agcccagttg gcttccgtca cggtccaaaa tctcttatca
    35341 acgacaatac agttgttttg gtctttggta caacgacaga ctacactcgt aagtatgact
    35401 tggacttggt tcgtgaagtt gctggtgacc agattgctcg tcgtgttgtg cttttgagtg
    35461 atcaagcttt tggtcttgaa aatgtcaaag aagtggccct tggttgtggc ggtgtcttga
    35521 atgatattta ccgtgtcttc ccttacatcg tttatgccca actctttgcc ctattgactt
    35581 cactcaaggt agaaaataaa ccagatacac cgtctcctac aggtacagta aaccgtgtag
    35641 tacaaggtgt cataattcac gaatatcaaa agtaagacag tgtttatgaa ttcttgacaa
    35701 gaggatttgt aaattatcag ataaaccata gattgtcagt acgctttcta tggtttgttt
    35761 gcttgagaga aatagtaaaa ggagaacaga atgaaagcat acacagagcg tgtatttgga
    35821 aatgttgagg gcgaggatgt cttggcctat cgatttgaga cagacggtgg ctaccaactt
    35881 gaggttatga cttatggcgc gaccatcttg cgctatgtcg cacctgacaa ggctggaaat
    35941 tttgccaatg ttatcttggg atttgatgac tttgatagtt atgtaggcaa tagtcccaag
    36001 catggagcaa gtgtaggtcc tgtagcgggt cgtattgcag gtgcgacctt tgagctcaat
    36061 ggtaagacct atgaccttga ggttaataat gctagcaact gtaatcacag tggttcaact
    36121 ggttgggatt ccagcttgtt tgaagttgaa gaagtaagcg atcatggctt gactctctac
    36181 acagagcgta cagatgggac aggagggttc cctggaaatc tcaagatttg gatcagttat
    36241 cacttggaag aaactggtgc ctatgaaatc agctacaagg taacgaccga tcaggatacg
    36301 ctggtcaatc caaccaacca cagctatttc aacttgtctg gtgatttcac gcagacgatt
    36361 gaccgtcatg tcttccaact aaacacagag ggcatttact caatcgctcc tgacggtgtt
    36421 cctgccaaaa ctccagaagc caaccgtgat gtggtcaaac acgtctacaa tggtaccttg
    36481 ttgaaggata tctttgcaga agaagatgag caaatccagc tggcatcagg tttggatcat
    36541 ccatttgccc ttcctgcagg ccatgacaat gctggattcc tttatgacca aaattcaggt
    36601 cgcttcctgc ttttcaagac agaagctcct tgctttgtgg tctacacagc aaactttgtg
    36661 gatgaaagtg tcatcatagg aggtcagcca atgctacagc acaatgggat tgctcttgaa
    36721 gcgcaagctt taccagatgc cattcacagt gaccttaaag gccaagtcat tcttaaggct
    36781 ggtcaaacct tcaccagtaa gacacgttat gaacttgttg tgaaataaaa aagctggtca
    36841 aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt gatactatgc
    36901 gttttgttat gaaatgattt actttatctt atcctgaaat ggtgttattt ttgagttatc
    36961 tggcttgact ttcttgatgg aaattatata atagttgtaa caataataat tacaacgaga
    37021 aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca gagacagttt
    37081 taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt ggtttagaaa
    37141 tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc ttggtacagc
    37201 tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac catttggcca
    37261 ttctcttacc cacacgcaag gctttggctg atgtcttgaa acacctgaca gatttacaga
    37321 ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg gaagatttgg
    37381 agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat attcgagaag
    37441 atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat gagttggggg
    37501 aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt catctttcag
    37561 tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta gaggataaat
    37621 tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat ttagcagtta
    37681 acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt ttagcctact
    37741 atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga gcacaagaag
    37801 ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac tcagatggca
    37861 tcgtgacctg tattcgttta gcaaggtaaa attaggaatt tttaataagt tataagtatt
    37921 gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga tgggtgagaa
    37981 ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg aaaaagaaat
    38041 gacaaattca aagtatatta ctcgtttgaa acgttcagag ggccagttgc gtgggattca
    38101 aaagatgatt gaaggagatc gtgacgcaac tgacagcagt gagatctagt gtagagcgcg
    38161 tgattgagat gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt
    38221 ctgaagctca aaaggaacgc ctagaaaagg ctatccgata cttgattaaa cggaaataaa
    38281 tgaatgtttt gagacgatat gtgcaaaggt ctattaacta ttagaatagt ttaatgtgag
    38341 tcaaaagaag ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtgttgaat
    38401 gtactgaccc c
//
LOCUS       DAVBNN010000016        37752 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBNN010000016 DAVBNN010000000
VERSION     DAVBNN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.016"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..270
                     /locus_tag="VQ847_000865"
     CDS             <1..270
                     /locus_tag="VQ847_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050224.1"
                     /translation="QHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYG
                     YEKSFQSLKQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(315..956)
                     /gene="plsY"
                     /locus_tag="VQ847_000866"
     CDS             complement(315..956)
                     /gene="plsY"
                     /locus_tag="VQ847_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3050225.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1092..3035
                     /gene="parE"
                     /locus_tag="VQ847_000867"
     CDS             1092..3035
                     /gene="parE"
                     /locus_tag="VQ847_000867"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3050226.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3455..5926
                     /gene="parC"
                     /locus_tag="VQ847_000868"
     CDS             3455..5926
                     /gene="parC"
                     /locus_tag="VQ847_000868"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3050227.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6058..7080
                     /locus_tag="VQ847_000869"
     CDS             6058..7080
                     /locus_tag="VQ847_000869"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3050228.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7136..7840
                     /locus_tag="VQ847_000870"
     CDS             7136..7840
                     /locus_tag="VQ847_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3050229.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            7905..8594
                     /locus_tag="VQ847_000871"
     CDS             7905..8594
                     /locus_tag="VQ847_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3050230.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8591..9514
                     /locus_tag="VQ847_000872"
     CDS             8591..9514
                     /locus_tag="VQ847_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3050231.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9529..10173
                     /gene="pcp"
                     /locus_tag="VQ847_000873"
     CDS             9529..10173
                     /gene="pcp"
                     /locus_tag="VQ847_000873"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3050232.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10341..10571
                     /locus_tag="VQ847_000874"
     CDS             10341..10571
                     /locus_tag="VQ847_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3050233.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10621..10701
                     /locus_tag="VQ847_000875"
     tRNA            10621..10701
                     /locus_tag="VQ847_000875"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10655..10657,aa:Tyr,seq:gta)
     gene            10711..10782
                     /locus_tag="VQ847_000876"
     tRNA            10711..10782
                     /locus_tag="VQ847_000876"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10743..10745,aa:Gln,seq:ttg)
     gene            10944..12146
                     /gene="rpsA"
                     /locus_tag="VQ847_000877"
     CDS             10944..12146
                     /gene="rpsA"
                     /locus_tag="VQ847_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3050234.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12232..12729
                     /locus_tag="VQ847_000878"
     CDS             12232..12729
                     /locus_tag="VQ847_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3050235.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12729..14384
                     /gene="dnaX"
                     /locus_tag="VQ847_000879"
     CDS             12729..14384
                     /gene="dnaX"
                     /locus_tag="VQ847_000879"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3050236.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14412..14606
                     /locus_tag="VQ847_000880"
     CDS             14412..14606
                     /locus_tag="VQ847_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3050237.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14756..15526
                     /gene="sufC"
                     /locus_tag="VQ847_000881"
     CDS             14756..15526
                     /gene="sufC"
                     /locus_tag="VQ847_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3050238.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15554..16816
                     /gene="sufD"
                     /locus_tag="VQ847_000882"
     CDS             15554..16816
                     /gene="sufD"
                     /locus_tag="VQ847_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3050239.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16827..18053
                     /locus_tag="VQ847_000883"
     CDS             16827..18053
                     /locus_tag="VQ847_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3050240.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18040..18480
                     /locus_tag="VQ847_000884"
     CDS             18040..18480
                     /locus_tag="VQ847_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3050241.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18534..19946
                     /gene="sufB"
                     /locus_tag="VQ847_000885"
     CDS             18534..19946
                     /gene="sufB"
                     /locus_tag="VQ847_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3050242.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20145..21386)
                     /locus_tag="VQ847_000886"
     CDS             complement(20145..21386)
                     /locus_tag="VQ847_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3050243.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21489..22598
                     /locus_tag="VQ847_000887"
     CDS             21489..22598
                     /locus_tag="VQ847_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3050244.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23244..23591
                     /gene="ssrA"
                     /locus_tag="VQ847_000888"
     tmRNA           23244..23591
                     /gene="ssrA"
                     /locus_tag="VQ847_000888"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23774..23861)
                     /locus_tag="VQ847_000889"
     tRNA            complement(23774..23861)
                     /locus_tag="VQ847_000889"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23825..23827),aa:Ser,seq:gga)
     gene            24023..24763
                     /locus_tag="VQ847_000890"
     CDS             24023..24763
                     /locus_tag="VQ847_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3050245.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24760..25671
                     /gene="pfkB"
                     /locus_tag="VQ847_000891"
     CDS             24760..25671
                     /gene="pfkB"
                     /locus_tag="VQ847_000891"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3050246.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25668..27620
                     /locus_tag="VQ847_000892"
     CDS             25668..27620
                     /locus_tag="VQ847_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3050247.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27784..30009
                     /locus_tag="VQ847_000893"
     CDS             27784..30009
                     /locus_tag="VQ847_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3050248.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30162..30590)
                     /locus_tag="VQ847_000894"
     CDS             complement(30162..30590)
                     /locus_tag="VQ847_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050249.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            30728..31870
                     /locus_tag="VQ847_000895"
     CDS             30728..31870
                     /locus_tag="VQ847_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3050250.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31879..33093
                     /gene="thiI"
                     /locus_tag="VQ847_000896"
     CDS             31879..33093
                     /gene="thiI"
                     /locus_tag="VQ847_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3050251.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33228..34052
                     /locus_tag="VQ847_000897"
     CDS             33228..34052
                     /locus_tag="VQ847_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3050252.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            34065..35231
                     /locus_tag="VQ847_000898"
     CDS             34065..35231
                     /locus_tag="VQ847_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3050253.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            35739..37232
                     /locus_tag="VQ847_000899"
     CDS             35739..37232
                     /locus_tag="VQ847_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3050254.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37245..>37752
                     /locus_tag="VQ847_000900"
     CDS             37245..>37752
                     /locus_tag="VQ847_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3050255.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT        11414 a         6859 c         8369 g        11110 t
ORIGIN      
        1 caacacgatt cttatcatcg gttcttagag agtaagggaa ttcaagcatc catgtcacgc
       61 aagggaaaca gccaagacaa tggtatgatg gagtccttct ttgggattct gaaatcggaa
      121 atgttttacg gttatgagaa gtcgtttcag tcgcttaagc aattggaaca agccattata
      181 gactatattg attactacaa caacaagaga attaaggtaa aactaaaagg acttagccct
      241 gtgcaataca gaactaaatc cttcggataa attaattgtc taacttttgg ggggcagttc
      301 acagaactgg cattttattt tttaggatct tgatgggtta ggttcaatcc ccaagggacc
      361 aaattttcag ttttattttt gatacgagct atattgtcct tatgacgaat gataatcaaa
      421 ctagcaagtg ctaagataat agcgatgaag agagagtcat agttactcag gataaaacca
      481 aaaagtggaa agagcagaac cccgataaca gccgcgatcg atgctgtgac actagacagt
      541 gaaatcatac tgccaagata gagagctcca aagaagataa tcgcaaggta gagacagaag
      601 ataggcgcaa atccgaaaat tactccagca ctggttgcga cagccttacc acctttaaat
      661 cctgcaaaga tagggaaggt atggccgata acagccaaaa gtccaaagat gagaggagaa
      721 acgccttgta gatgaaaaat aatcggaagc agcgttgcta gggttccttt gaaaaagtca
      781 atcacaaagg ttgccatacc agctttctta cctaaaatgc ggaaggtatt ggtcgttcca
      841 gtgttaccag aaccatgctc gcgtagattg atttgaaaga atacttgtcc aatccagaga
      901 ccagatggaa tcgaacccag cagataggct aggattaata aaactattgt aatcatactc
      961 ctattatatc atgaattggg aaagaaaagc agagaatctc tgctaaaatt gtcacatcgg
     1021 agaaagaaaa attttgcaaa atccttggaa aacctgtaga atagtaaaga tgaacgaata
     1081 ggaggttcct tgtgtcaaaa aaggaaatca atattaacaa ttataatgat gatgctattc
     1141 aggtgctaga agggttggat gcggtccgaa aacgtccagg gatgtatatt ggatcgaccg
     1201 atggcgctgg tcttcatcac ctagtttggg aaatcgttga taatgcagtc gatgaagcct
     1261 tgtctgggtt tggtgatcgt atcgatgtaa ccatcaataa agacggtagt ctaacggttc
     1321 aagaccatgg acgtgggatg ccgacaggta tgcacgctat gggaattcca actgttgagg
     1381 ttatctttac cattcttcat gccggaggga aattcggtca aggtggctat aagacatcag
     1441 gtggacttca cggagtgggt tcttccgttg ttaacgccct ttctagctgg ttagaagttg
     1501 aaattacccg tgatggcgca gtttacaagc aacgtttcga aaatggtgga aaacctgtca
     1561 cgactttgaa gaaaatcggt acagcaccca agtctaaaac aggcaccaaa gttactttta
     1621 tgcctgacgc gactatattt tctacgacag atttcaagta caataccatt tcagagcgcc
     1681 ttaatgaatc agcctttctc ttgaaaaatg tgaccttgtc tttaacggac aagcgaacag
     1741 atgaagcgat tgagttccac tatgagaatg gagtacaaga ttttgtttct tatctcaacg
     1801 aagataagga aatcttgacg ccagttcttt actttgaagg ggaagacaat ggttttcaag
     1861 tggaagtagc cctccagtac aatgacggat tctcagataa cattctatcc tttgtcaata
     1921 acgttcgcac caaggacggt ggaacgcacg agacaggact caagtctgcc attaccaagg
     1981 tcatgaatga ctatgcacgt aaaacaggtc ttctcaagga aaaagataaa aaccttgaag
     2041 gttcagacta tcgtgaggga ctagcggccg ttctttctat cttagttcct gaagaacact
     2101 tgcagtttga aggacagacc aaggataaac taggaagccc cctagctcgc ccagttgtgg
     2161 atggaatagt ggctgataag ttgacctttt tccttatgga aaatggggaa ttagcttcta
     2221 acctcatccg caaggctatc aaggcccgtg atgctcgtga agcagcacgt aaggcgcgtg
     2281 atgagagccg aaatgggaag aaaaacaaga aagataaggg cttgttgtct gggaaattga
     2341 ccccagccca atctaagaat cctgctaaga atgaactcta tctagttgag ggggactctg
     2401 ccggtggttc tgccaaacaa ggtcgtgacc gcaagttcca ggctattcta cctcttcgtg
     2461 gtaaggttat caatacagcc aaggccaaga tggcggatat cctcaaaaat gaagagatca
     2521 ataccatgat ttataccatt ggtgcgggtg ttggagcaga cttctctatt gaagatgcca
     2581 actatgataa gatcattatc atgaccgatg cggataccga cggtgcccat atccagacct
     2641 tgctcttgac atttttctac cgttacatgc gtccgctagt cgaggcaggt catgtctata
     2701 ttgccctccc acctctttac aagatgtcca aaggtaaagg aaagaaagaa gaagtggcct
     2761 acgcttggac ggacggagaa ctagaagaac tccgtaaaca gttcggtaaa ggcgctaccc
     2821 tccaacgata caaaggactt ggtgagatga atgcggacca gctctgggaa acaaccatga
     2881 acccagaaac acgtaccctc atccgtgtca caattgaaga tttagcgcgc gccgaacgcc
     2941 gcgtcaatgt tctcatggga gataaggtag aaccacgccg taaatggatt gaagataatg
     3001 tcaagtttac gctagaagaa gcgacagtgt tttaatgaaa gaaaataata tgttagtaaa
     3061 ctggaaatta gagtcggatg tgaatgacta tgtgaaaaag cagtttgaaa atcttggttt
     3121 gaaaaaattg caggattatt aatgaagaat ctgctatgag tgcttatctc aaagaggcgc
     3181 ttaagggagc ggctaagaca caaactaaga ctaattttgg aaaaccagat tttcatattg
     3241 aaaaatacaa acaggatagt ttggttactt atcgtaactg aacacgggag gaattcccgt
     3301 aaaatatctt ttactgcata aaaacctact ctacattctt tgaaaggagt tgaacacgcc
     3361 ctagatactg tgtgaaaaag ataaattctc ttgtgagttt gcttacttca agaattttct
     3421 attttcactt ggtattttat gggctttgta tcttatgtct aacattcaaa acatgtccct
     3481 ggaggacatc atgggagagc gctttggtcg ctactccaag tacattattc aagaccgggc
     3541 tttgccagat attcgtgatg ggttgaagcc ggttcagcgc cgtattcttt attctatgaa
     3601 taaggatagc aatacttttg acaagagcta ccgtaagtcg gccaagtcag tcgggaacat
     3661 catggggaat ttccacccac acggggattc ttctatctat gatgccatgg ttcgtatgtc
     3721 acagaactgg aaaaatcgtg agattctagt tgaaatgcac ggtaataacg gttctatgga
     3781 cggagatcct cctgcggcta tgcgttatac tgaggcacgt ttgtctgaaa ttgcaggtta
     3841 ccttcttcag gatatcgaga aaaatacagt tccttttgca tggaactttg acgatacgga
     3901 gaaagaacca acggtcttgc cagcagcctt tccaaacctc ttggtcaatg gttcgactgg
     3961 gatttcggct ggttatgcca cagacattcc tccccataat ttagctgagg tcatagatgc
     4021 tgcagtttac atgattgacc acccaactgc aaagattgat aaactcatgg aattcttgcc
     4081 tggaccagac ttccctacag gggctattat tcagggtcgt gatgaaatca agaaagctta
     4141 tgagactggg aaagggcgcg tggttgttcg ttccaagact gaaattgaaa agctaaaagg
     4201 tggtaaggaa caaatcgtta ttactgagat tccttatgaa atcaataagg ccaatctagt
     4261 caagaaaatc gatgatgttc gtgttaataa caaggtagct gggattgctg aggttcgtga
     4321 tgagtctgac cgtgatggtc ttcgtatcgc tatcgaactt aagaaagacg ctaatactga
     4381 gcttgttctc aactacttat ttaagtacac cgacctacaa atcaactaca actttaatat
     4441 ggtggcgatt gacaatttca cacctcgtca ggttgggatt gttccaatcc tgtctagcta
     4501 catcgctcac cgtcgagaag tgattttggc gcgttcacgc tttgacaaag aaaaggctga
     4561 gaaacgtctc catatcgtcg aaggtttgat tcgtgtgatt tcgattttgg atgaagtcat
     4621 tgctcttatc cgtgcttctg agaataaggc ggacgccaag gaaaacctca aagttagcta
     4681 tgattttacg gaagaacagg ctgaggctat cgtaactttg caactgtacc gtttgaccaa
     4741 taccgatgtg gttgtcttgc aggaagaaga agcagagctt cgtgagaaga ttgctatgct
     4801 ggcggctatt atcggtgatg aaaggactat gtacaatctc atgaagaaag aacttcgtga
     4861 ggtcaagaag aaatttgcaa ctcctcgttt gagttcttta gaagacactg cgaaagcaat
     4921 tgagattgat acagctagtc ttatcgctga ggaagatacc tacgtcagcg tgaccaaggc
     4981 aggttacatc aagcgtacca gtccacgttc ctttgcggct tccaccttgg aagaaattgg
     5041 caagcgtgat gatgaccgtt tgatttttgt tcaatctgcc aagacaaccc agcacctctt
     5101 gatgttcaca agtcttggaa atgtcatcta cagaccaatc catgagttgg cagatattcg
     5161 ttggaaggac atcggagagc atctgagcca aaccatcaca aactttgaaa cgaatgaaga
     5221 aatcctttat gtggaagtac tggatcagtt tgacgatgcg acaacctact ttgcagtgac
     5281 tcgccttggt caaatcaaac gggtagagcg aaaagaattc actccatggc ggacctatag
     5341 atctaagtct gtcaagtatg ctaagctcaa agacgataca gatcagattg tagcagtggc
     5401 tccgattaaa ctagatgatg ttgtcttggt tagtcaaaat ggttatgccc tgcgtttcaa
     5461 tatcgaagag gttccggttg tcggtgctaa ggcagcaggt gtcaaggcta tgaatttgaa
     5521 agaagatgat gtcctccaat ctggctttat ctgtaatact tcgtccttct acctcttgac
     5581 ccagcgtgga agcttgaaac gtgtttctat tgaggaaatt ctagcaacca gccgtgccaa
     5641 acgaggatta caagtcttgc gtgagttgaa aaacaaaccg catcgtgtct tcttggcagg
     5701 agcagttgca gagcaaggat ttgttggcga tttcttcagt acggaagtgg atgtgaacga
     5761 ccaaactctg cttgtccaat ccaataaagg aacaatctat gaaagccgat tgcaagactt
     5821 gaacttgtca gaacgcacta gcaatggaag cttcatttct gacacgattt cagatgaaga
     5881 agtttttgac gcttatcttc aggaagtagt tactgaagat aaataagtga aatgaagaat
     5941 cagttctaag agctggtttt tattggagaa attttctgaa aattacaaaa tatacttgct
     6001 attttagaaa aatagtgtag aatataagaa ataggttttt agaataagga gtggaatatg
     6061 acagtaacga ttgattggga aaacctcggt ttttcctata tgaaattacc ttatcgctat
     6121 cttgctcatt tcaaaaatgg acaatgggat caaggagagc ttacagagga tgcaactttg
     6181 catatttcag agtcttctcc aagtcttcac tatggacaac aagcatttga aggtttgaaa
     6241 gcttatcgta ctaaggatgg cagtgttcaa ctgttccgtc ctgatgaaaa tgctaaacgt
     6301 ctgcaacgta catgtgaccg tctcttgatg ccacaagttc cgacagacat gtttgtagaa
     6361 gcttgtaaag cagttgtccg tgcgaatgaa gaatacgtac caccatacgg aacaggtgga
     6421 accttatatc ttcgccctct tttgattggt gtcggagata ttatcggggt aaaaccggca
     6481 gaagagtaca ttttcaccat ctttgctatg ccagttggaa attactttaa aggtggtttg
     6541 gtcccaacca acttcttgat tcaggatgag tacgaccgtg cagcaccaaa tggtacaggt
     6601 gcggctaagg ttggtggaaa ctatgctgca agtctcttac caggaaaaat ggccaagtca
     6661 cgtcatttct cagatgttat ctatctggac ccatcaactc atacaaagat tgaagaagtc
     6721 ggatcagcta acttctttgg aattacagct gataatgaat ttgtaacacc attgagtcca
     6781 tctatcttgc catctattac caagtattcc ttgctttatt tggcagaaca tcgcttggga
     6841 ttaactccta ttgagggtga tgttccaatt gataatcttg accgttttgt agaggcaggt
     6901 gcctgtggta cagcagcggt tatttctcca attggaggta ttcaacatgg tgatgatttc
     6961 catgtattct atagtgaaac agaagtaggt cctgtgacgc gtaaattata taatgaattg
     7021 acgggtattc agtttggcga tattgaagcg ccagaaggtt ggattgtaaa agtagattaa
     7081 aataaaccaa aggagatttt ttatgaaata gaaaaagtgg ctcttaacag caggagtggt
     7141 cctgagcacg tcagctattt tagtggcttg tggaaaaact gataaagaag cagatgcacc
     7201 gacaacattt tcttatgtct atgcagtaga tccagcatca ttgggctaca gtatagcgac
     7261 tcgaacatcg aggacagacg ttattggaaa tgttattgat ggtttgatgg aaaatgataa
     7321 atacggcaat gttgctcctt ctcaaaaaga ctatgatttg aacggtacag gatgggctcc
     7381 aagctatcaa gatccagcgt cttacttgaa tattatggat ccaaaatctg gttctgccat
     7441 gaaacacctt ggcattacga aaggaaaaga taaggatgtt gtagctaaac ctggtttgga
     7501 taaatataag aaattgttag aagatgctgt ttctgagacc actgacctag agaagagata
     7561 tgaaaaatat gccaaagctc aagcttggtc gacagatagt tcattattga tgccaacagc
     7621 ttcatctggt ggttttccag ttgtaagtaa cgtagtacca ttctcaaaac catactcaca
     7681 agttggtatt aagggggaac catatatctt taaaggaatg aaattgcaaa aagatattgt
     7741 tacaacaaaa gaatataacg aggtttttaa aaaatggcaa aaagaaaaat tggaatccaa
     7801 tagcaaatac caaaaagaac tagaaaaata cattaaataa ggaatggtat tgatcttgat
     7861 aaaattttta aaatactgtc attttgaata taaaggagtt tgatatggag tggattagat
     7921 taataggaat agcaatcatt gttgtgggtt ttattttaaa atttgataca attgcaacag
     7981 tagtcttagc tggtttggtt acagctttag tttcaggtgt ttctctcgtt gaatttttgg
     8041 agattttggg aaaagaattt agcaatcagc gagtgctcac gatttttatg gttaccttgc
     8101 ctcttgtggg gctgtcagaa acctttggac tcaagcaacg atcaatcgat ttgattcgaa
     8161 agattaaagg tctgacagtt ggaaacttct atacagttta tttctttatt cgagagttag
     8221 ctggtttctt ttcaattcgt ctaggaggac accctcagtt tgtcagacct ttggttcaac
     8281 ctatgggaga agcagctgca gagtctcaat taggtagaaa gttaacagag gttgaagatg
     8341 agacaataaa agcgcgtgcg gctgcgaatg aaaattttgg aaatttcttt gctcaaaata
     8401 cgtttgtagg tgctggggga gtcctcttga tagggggaac attagatcag ttaggctatg
     8461 aaagcaatta tgcagggatt gcttctacat ctattattgt tgctgttata acacttattg
     8521 tagtggggat ttacaattat ttatttgata aaaaattgat atcaaaaaag actaggggag
     8581 gagaacaaaa atgacagagt tggcaaagca actattagag ttgacctata ttgtgattgg
     8641 ttgtcaattt ctccatacag cctattgtag ttataaagat aaaacaaacc cagttcgact
     8701 tgggacatct gcattttgga ctctattgtc tattacgttt ataggtggtt cctatatgcc
     8761 aaatatgagt attggtatta ttgtaatcct attatcgctg ttaacattgt ttaagcaagt
     8821 ccgtatcgga accttgccat ccttagatga aatgaaagcc aatattgaat ctaacaggtt
     8881 gaaaaataaa atttttattc cagttatgct gatggcaata cttgcgttgg tcttagcgca
     8941 aatgattcca gaatttagca agatttcgat tagccttgcc gccttgtttg ctacaatttc
     9001 tgttcttgtg attaccaata gtcaccctaa gagtctgtta tcagaaaata atcgaatgac
     9061 tcagcaagtt tcaacaagtg gtattgttcc tcaattatta ggggctttgg gggctatttt
     9121 tactgtagca ggtgttggtg atgttatctc tcatctgatt agcggtattg ttccttcaga
     9181 tagtcgcttt ataggagttt tggcttatgt tcttggaatg gttctattca caatgattat
     9241 gggaaatgct tttgcagcat tcaccgttat tacagcaggt gttggagttc cctttgtatt
     9301 tgctctggga gctaatccaa ttgtggctgg tgctcttgcc atgacagcag gttattgtgg
     9361 gaccttattg accccaatgg ctgctaattt taacgctcta ccagcagcat tgatggatat
     9421 gaaagatcag aatggcgtta taaaggctca agcaggtgtt gctctagtaa tgattgttat
     9481 tcacatattc ttaatgtact ttctcgcatt ttagtaaagg aaaataaaat gaaaatattg
     9541 gttacaggtt ttaatccttt tggaggtgaa aagattaatc cagctttgga ggctgtaaaa
     9601 ttattaccat ctgagattaa tggggctgaa gttcgctggg tagaaattcc aacggttttt
     9661 tataagtcgt cagaagtttt agaggcagaa atattacgat atcaaccaga tgctgtactt
     9721 tgtattggac aagcaggcgg caggaccggc ttaacacctg aacgagtggc tattaatcaa
     9781 gatgatgctc gcatacctga taacgaaggc aatcaaccaa ttgatacacc gattcgtatt
     9841 gatggagcat cggcctattt tagtagttta cctatcaaag cgatggtaca agctatcaaa
     9901 aaacagggac ttccggcagt tgtatccaat agtgcaggaa cctttgtttg caatcatttg
     9961 atgtaccaag ctctttattt agtggataaa aaattcccta atatgagagc aggtttcatg
    10021 catattccat atatgatgga acaagtagta aataagccga atactgcagg aatgagtcta
    10081 tgtgatattg taagaggcat agaggtagct attgaagcta ttgtagacta caaagataag
    10141 gatttgcagt tagtaggcgg tgagactcac tgataaccta aaaaggatag tcaattatgc
    10201 ttgtttacta actattaact atgctaaatc aattgaggtt gtttacataa aactctatat
    10261 cagagaagcc tgatatagag ttttttcttg ctagttttag gattttcttg taaaatagaa
    10321 aaagtgaaga gaggtatgaa atgagcaaga aagataaaaa aatcgaaatt caagtagcgg
    10381 atgccaaagt taatgttggt aaagacagtt ttgaaggtta tacattgact atcggtaaaa
    10441 aagttatcgg agaaattgcc gaattagacg gacaatttgc cattataaag aatgggaatg
    10501 tcgatagttt ttataaaaaa ttggaaaaag ctgtggaaat tttgattgaa aattataatt
    10561 tagcaaaata agtcttgttt ttttgaaatt ttcatgatat aatagtccat gttgattgta
    10621 ggagagatag cgaagaggct aaacgcggcg gactgtaaat ccgctccttc gggttcgggg
    10681 gttcgaatcc ctctctctcc atttcattaa tggggtatag ccaagcggta aggcaaggga
    10741 ctttgactcc ctcatgcgtt ggttcgaatc cagctacccc agttcttagg taataatcaa
    10801 gataaaaagc aaaatatctt agggtatttt atttttataa ttgaaagacg tgaatgatat
    10861 gaacatgtcc ttgcgggtgc ttaggaaaaa aattataagt atgtcaagtt taagaaaaac
    10921 ttgattgttg gaggattttt tagatgaacg aatttgaaga tttgctaaat agcgttagtc
    10981 aagttgagac tggtgatgtt gttagtgctg aagtattgac agttgatgcg actcaagcta
    11041 acgttgcaat ctctggaact ggtgttgaag gtgtcttgac tcttcgcgaa ttgacaaacg
    11101 atcgtgatgc agatatcaat gactttgtta aagtaggaga agtattggat gttcttgtac
    11161 ttcgtcaagt agttggtaaa gatactgata cagttacata ccttgtatct aaaaaacgcc
    11221 ttgaagctcg caaagcatgg gacaaacttg ttggtcgcga agaagaagtt gttactgtta
    11281 aaggaacgcg tgccgttaaa ggtggacttt cagtagaatt tgaaggtgtt cgtggattta
    11341 tcccagcttc aatgttggat actcgtttcg tacgtaacgc tgagcgtttt gtaggtcaag
    11401 aatttgatac taaaatcaaa gaagttaacg ctaaagaaaa ccgcttcatc ctttcacgtc
    11461 gtgaagttgt tgaagcagct actgcagcag ctcgcgctga agtattcggt aaattggctg
    11521 ttggtgatgt tgtaactggt aaagttgctc gtatcacaag cttcggcgct ttcatcgacc
    11581 ttggtggtgt tgacggattg gttcacttga ctgaattgtc acatgaacgt aacgtatcac
    11641 caaaatcagt tgtaactgtt ggtgaagaaa ttgaagtgaa aatccttgat cttaacgaag
    11701 aagaaggacg tgtatcactt tcacttaaag caacagtacc aggaccatgg gatggcgttg
    11761 agcaaaaatt ggctaaaggt gatgtagtag aaggaacagt taaacgtttg actgacttcg
    11821 gtgcatttgt tgaagtattg ccaggtatcg atggacttgt tcacgtatca caaatttcac
    11881 acaagcggat tgaaaatcca aaagaagctc ttaaagttgg tcaagaagtt caagttaaag
    11941 ttcttgaagt taacgcagat gcagaacgcg tgtcactttc tattaaagct cttgaagaac
    12001 gtccagccca agaagaagga caaaaagaag aaaaacgtgc tgctcgtcca cgtcgtccaa
    12061 gacgtcaaga aaagcgtgat ttcgaacttc cagaaacaca aacaggattt tcaatggctg
    12121 atttgtttgg tgatatcgaa ctttaatcaa attgaaaatt cacaaaatcc tttgtttact
    12181 aaacaaggga tttttctttt gtctctgctc cttttttgat ataatagttc tatgttaaaa
    12241 tcagaaaaac aatcacgtta tcaaatgtta aatgaagaat tgtccttcct attggaaggc
    12301 gaaaccaatg ttttggctaa tctttccaac gccagtgctc ttataaaatc acgttttcct
    12361 aataccgtat ttgcaggctt ttatttgttc gatggaaagg aattggtttt aggtcccttc
    12421 caaggaggtg tttcctgcat ccgtattgca ctaggcaagg gtgtttgtgg tgaggcagct
    12481 cactttcagg aaactgttat tgttggagat gtgacgacct atctcaacta tatttcttgt
    12541 gatagtctag ctaaaagtga aattgtggtg ccgatgatga agaatggtca gttacttgga
    12601 gttctggatc tggattcttc agagattgag gattacgatg ctatggatcg agattatttg
    12661 gaacaatttg tcgctatttt gcttgaaaag acaacatggg actttacgat gtttgaggaa
    12721 aaatcttaat gtatcaagca ctttatcgaa aatatagaag tcaaaacttc tcccagttag
    12781 ttggtcaaga agttgtggct aagactctta aacaagcggt ggagcaagag aaaataagtc
    12841 acgcttatct tttttctggt cctcgtggaa cgggaaaaac cagtgttgct aaaatctttg
    12901 ccaaggctat gaactgtccc aatcaagtgg gtggcgaacc ttgcaataac tgctatattt
    12961 gtcaagcagt gacggacggt agtttagaag atgtcattga aatggatgca gcttctaata
    13021 atggggtaga tgaaattcgc gaaattcgtg ataaatctac ctatgcgcct agccttgctc
    13081 gttataaggt ttatatcata gatgaggttc acatgctgtc tacaggggct tttaatgccc
    13141 tcctaaagac gctggaagaa ccaacacaga atgtagtctt tattttggcc actactgaat
    13201 tgcacaagat tcctgctact attctatccc gtgtgcaacg ttttgagttt aaatcaatta
    13261 agacacagga tattaaggaa catattcact atatcttaga aaaagaaaat atcagttctg
    13321 aaccagaggc tgtggaaatc attgccagac gggcggaagg tggaatgcgg gacgccttgt
    13381 ctattttgga tcaagccctg agtttgacac agggaaatga gctgacgact gctatctctg
    13441 aagaaattac tggcaccatt agcctatcag ccttggatga ttatgtggcg gccttgtctc
    13501 aacaggatgt tcccaaagct ttgtcttgct tgaatcttct ttttgacaat ggtaagagca
    13561 tgactcgttt tgtgaccgat cttttgcact atttaagaga cttgttaatt gttcaaacag
    13621 ggggagaaaa tactcatcat agttcagtct ttgtagaaaa tttggcactt cctcaaaaaa
    13681 atctgtttga aatgattcgc ttagcaacag tgaatttagc agatattaag tctagtttgc
    13741 agcccaagat ttatgctgaa atgatgaccg tccgtttggc ggaaatcaag cccgaaccag
    13801 ctctatcagg agcggttgaa aatgaaattg ctacgctgag acaggaagtt gcccgtctca
    13861 aacaagagct ttctaatgca ggtgcggttc ctaaacaagt tgcaccagct cctagtcgac
    13921 cagctacggg caaaacagtc tatcgtgtcg atcgcaataa agtgcaatct atcttacaag
    13981 aggccgtcga aaatcctgat ttagcacgtc aaaatctaat tcgtttgcag aatgcctggg
    14041 gagaggtaat tgaaagtcta ggtgggccgg acaaggctct gctagttggt tctcaaccgg
    14101 ttgctgccaa tgaacaccat gctattcttg cttttgagtc taacttcaat gctggtcaaa
    14161 ctatgaaacg agacaatctc aataccatgt ttggtaatat cctcagtcag gcggcaggtt
    14221 tttcacctga gattttagct atttccatgg aggaatggaa agaagttcgc gcagcctttt
    14281 cagccaaagc caaatcttct caaactgaaa aagaagtaga agaaagcctg attccagaag
    14341 gatttgaatt tttggctgat aaagtgaagg tagaggaaga ctaaagaaag atttcatgat
    14401 acaataagtt tatgaataaa caacaattta ttattatggc gctatttaca gctgctgaga
    14461 cctatttttt caatgaagcc tggatgactg gccgctatat tatggcagcc ttttgggcaa
    14521 ttttactctt tagaaatttc cgagtcagtt atgtgatggg taaaattgtt gatgtcatcg
    14581 atcagcattt taataggaaa gactagccct cagcttccag acaaaatcaa agccttttag
    14641 gctttttttt gttatactag aaaagtatat ttatagaatt tttgctctat ttctggggaa
    14701 atcagacgtt tttctagtaa gtactgtaaa agttttgaaa aagaaaggaa ctatcatgtc
    14761 agtaatagag atcaaagatc ttcacgttga gattgaagga aaagaaattt taaaaggggt
    14821 taacctgacc ctgaaaacag gagaaattgc cgctatcatg ggaccaaatg gtacaggtaa
    14881 atcgactctt tctgccgcta tcatgggaaa tccaaactat gaagtaacta aaggtgaagt
    14941 tttgtttgat ggcgtaaaca tccttgagtt ggaagtggat gagcgtgcgc gtatgggact
    15001 tttccttgct atgcaatacc catcagaaat ccctggaatt accaatgctg agtttcttcg
    15061 tgccgctatg aatgcgggta aagaagatga tgagaagatt tcagttcgtg agtttattac
    15121 taagctagat gaaaaaatgg aattgctcaa catgaaagaa gaaatggcag agcgttacct
    15181 caacgaaggc ttctctggtg gtgagaaaaa acgcaatgaa attcttcaac ttttgatgtt
    15241 ggagccaaca tttgctcttt tggacgagat tgactcaggt cttgatattg acgctcttaa
    15301 agttgtgtct aaaggtgtca atgccatgcg tggtgaaggt tttggtgcta tgatcatcac
    15361 tcactaccaa cgtcttttga actatatcac acctgatgtg gtacacgtga tgatggaagg
    15421 tcgtgttgtc ctttctggtg gtccagaatt ggctgcgcgt ttggaacgtg aaggatacgc
    15481 aaaattagct gaagaacttg gctacgacta caaggaagaa ttgtaatttc ctcgtatctt
    15541 ttaggagaag taaatgacta gagaaaatat taaacttttt tcagaaatgc acgctgaacc
    15601 aagctggttg gctgatctcc gtcaaaaagc ttttgacaag attgagactt tggaattacc
    15661 agttattgag cgtgtcaaat tccaccgttg gaatctgggt gatggaacga ttacagaaaa
    15721 tgagccatca gcaaatgttc cagatttcac agctttagat catcacttga agttggtgca
    15781 agtaggaact caaactgttt tcgaacaaac tccagttgag ttagctgaac agggtgttgt
    15841 cttcacagac tttcactcag ctttagaaga aattccagag ctgatcgaag aattcttcat
    15901 gtcatctgtt aagtatgatg atgacaagtt ggcggcttac cacacagctt actttaacag
    15961 tggtgctgta ctctatattc cagataacgt agaaatcaca gagccaattg aaggaatttt
    16021 ctaccaagat agcgatagca atgtgccgtt taacaagcat attatgatta tcgctggtaa
    16081 aaattctaag attagttatc tggagcgttt agagtcacgc ggtgaaggaa gtgacaaagc
    16141 aactgccaat atcacagtgg aagtgattgc acattctggt gcgcaagtca agtttgctgc
    16201 tatcgaccgt ctaggtgaaa acgtcactgc ctacattagc cgtcgtggta aattaggcaa
    16261 cgatgcaagt attgactggg ctatcggtgt catgaacgaa ggaaatgtcg ttgctgattt
    16321 tgatagtgac ttgattggta atggtagcta tgctgacctc aaggttgtag ctctttcaag
    16381 tggtcgtcag gtacaaggga ttgatactcg tgtaactaac tatggctgca actctatcgg
    16441 aaatatccta caacatgggg ttatccttga aaaagcaact ttgactttca atggtatcgg
    16501 ccacatcatc aagggtgcta agggagcaga tgcccaacaa gagagccgtg ttctcatgct
    16561 ttcagaccaa gcgcgttcag atgctaaccc aattcttttg attgatgaaa atgatgtcac
    16621 tgcaggacac gcagcgtcta tcggacaagt tgatccagaa gacatgtatt acctcatgag
    16681 tcgtggattg gataaggcaa ctgcagagcg tttggttgtt cgtggtttcc ttggatctgt
    16741 tatcgtggag attccagtca aggaagttcg tgatgaaatg attgcaacta tcgaagagaa
    16801 attgtcaaaa cgctaagggg aagcctatgt tagatgtaga agcgattcgc aaggattttc
    16861 caattttaga tcagattgtc aatgatgaac ctctggtcta tctggacaat gctgcgacga
    16921 cacaaaaacc actagtagtt ctgaaagcta ttaacagtta ctatgagcag gacaatgcca
    16981 atgttcaccg tggtgtccat accttagcgg aacgagcgac agcttcttat gaagctgctc
    17041 gtgaaaccat tcgtaagttt attaatgcag gctctacaaa ggaagttctc tttaccagag
    17101 gaacgacaac cagccttaac tgggtggcac gctttgctga ggaaattctc actgagggag
    17161 accaggtctt gatttcagta atggaacacc attctaatat cattccatgg caggaagctt
    17221 gtcgaaagac tggagcagag cttgtctatg tctatcttaa agacggtgcc ttggatatgg
    17281 aggatttgcg agctaaattg actgataagg ttaaatttgt ttccctagct catgcctcca
    17341 atgttcttgg tgtggtcaat ccgatcaagg aaatcactca attagcccac caagttgggg
    17401 caatcatggt agtggatggt gctcaatcta cacctcatat gaagattgat gtccaggact
    17461 tggatctgga ctttttcgcc ttttcgggtc acaagatggc tggtccgact ggtatcggtg
    17521 tcctttacgg caaagaaaag tatcttgagc aaatgtctcc agtagaattt ggcggcgaga
    17581 tgattgattt tgtctacgag caatccgcta gttggaagga attgccttgg aaatttgagg
    17641 ctggaacgcc aaatatggca ggagctattg gacttgcgac tgcagttgat tatctggaaa
    17701 agattggtat ggatgccgtt gaagctcatg aacaggaatt gattgcgtac gtctatccaa
    17761 aactgcaggc aattgaggga ttgaccattt acggttctca ggatttggct caacgttcgg
    17821 gtgttattgc ctttaaccta ggtgatctcc atcctcacga tcttgcgacg gctctggatt
    17881 atgaaggagt ggctgttcgt gctggtcacc attgtgcgca acccttgctt cagtatttgg
    17941 aagtctcagc aacagctcgt gcaagttttt atatctataa taccaaggca gattgcgaca
    18001 aactagtcga tgccctacaa aagacaaagg agtttttcaa tggcactttc taaactagat
    18061 agcctttata tggcagtggt agcagaccat tcgaaaaatc cacatcacca agggaagtta
    18121 gaagacgctg agcaaatcag tctcaacaat ccgacttgtg gagatgtcat caatctctct
    18181 gtcaagtttg atgcagagga ccgtttggaa gatattgctt ttctaaattc aggatgcacg
    18241 atttcaactg cttctgctag tatgatgaca gatgccgttt taggaaaaac caaacaagaa
    18301 attttagaac tggcgactat tttttctgaa atggttcaag ggcaaaaaga tgagcgtcaa
    18361 gaccaacttg gagacgcggc attcttgtca ggtgttgcca aattccctca aagaatcaag
    18421 tgtgcaaccc tagcttggaa tgcccttaag aaaacaattg aaaatcaaga aaaacagtaa
    18481 gacaagtttc ttttgtctta tgaattatta gaaatgaaga aagaaaggat attatggctg
    18541 aagaaagagt agaaccaaaa ccaattgacc ttggtgaata taaatttggt ttccatgacg
    18601 atgtagagcc tgtcttatcg acaggaaaag gactcaacga aggtgttatt cgtgaattat
    18661 ctgctgctaa gggtgagcct gagtggatgt tggagttccg tttgaagtct tatgaaacct
    18721 tcaaaaaaat gcccatgcaa acttggggag cagacttgtc agagattgac tttgatgact
    18781 taatctacta ccaaaaacca tctgacaaac cagcccgttc ttgggatgat gtacctgaaa
    18841 agattaaaga aacctttgaa cgtatcggga ttccagaagc tgaacgtgct tatttagcag
    18901 gggcttctgc ccagtacgag tcagaagtgg tttaccacaa catgaaggaa gagttccaaa
    18961 aattaggtat tatctttaca gatacagatt ccgcactcaa ggaataccca gacttattta
    19021 atcaatactt tgcgaagttg gtaccgccga cagataacaa gttggcagcc ctcaactcag
    19081 cagtatggtc gggtggaact tttatctacg tgccaaaagg tgtcaaggta gatattccac
    19141 ttcaaactta tttccgtatc aataacgaaa atataggtca gttcgaacgt accttgatta
    19201 tcgttgatga gggagcaagc gtccactacg tagaaggatg tacagcacca acatattcaa
    19261 gcaatagctt acacgctgcc attgtagaaa tttttgcttt ggacggagct tatatgcgtt
    19321 atacaactat ccaaaactgg tctgataacg tctataactt ggtaacaaag cgtgctaagg
    19381 ctcaaaagga tgccactgtt gagtggattg atggaaactt gggtgccaaa acgactatga
    19441 aatatccatc tgtttacctt gatggagaag gagcgcgtgg taccatgctc tctatcgcct
    19501 ttgctaatgc agggcaacac caagacacgg gtgctaagat gattcacaat gctccacata
    19561 ccagctcgtc tattgtgtct aaatccatcg ctaaaggtgg aggaaaggtt gactaccgtg
    19621 gacaagtcac ctttaacaag aactctaaga aatctgtttc ccacattgaa tgtgatacca
    19681 ttatcatgga tgacttgtca gcatcagata ctattccatt taatgaaatt cacaactcgc
    19741 aagtggcttt ggaacacgaa gccaaagtat ctaagatttc agaagagcaa ttgtattatc
    19801 tcatgagccg tggattgtca gaatctgagg caactgaaat gattgtcatg ggatttgtag
    19861 aaccctttac aaaagaactt ccaatggaat acgcagttga gctgaaccgc ttgattagct
    19921 atgaaatgga gggatcagtt ggataaaatt tgattttata ctcttcgaaa atctcttcaa
    19981 accacgtcag catcgcctta tcgtatgtat ggttactgac ttcgtcagtt tcatctacaa
    20041 cctcaaaaca gtgttttgag caacctgcgg ctagcttcct agtttgttct ttgattttga
    20101 agatgaactt gtatcaaaaa atcgcggttt aaaatcgcga ttttttataa tttctcgtta
    20161 acaaagcgga caaactgatt ccaccaaact tttaagaaga aggctttttc aattttcttg
    20221 tctgctacca tttcgaaact agggcgctct gtggtgatgt aaccttgacc aatcaagtcc
    20281 ttgtcttcat aagtcaaatg gccaaccact gttccagctt caagtggtgc tgggattgct
    20341 ttggaatcag gtgtgaattg aacagattga gaagattgat tcccaacacg ttcgattaga
    20401 tagatatcct ctggagccac tgcagttact gtatcttctt ttccatcttg tacaggggct
    20461 ttgctatctt gataggcatc gccttgttga acgattttgc gaagtgtaaa tgtagaagaa
    20521 atataatcca ttagggaaga tgtagctgta aatcgagcgt aaggattatt gtcttgatga
    20581 tctgcattta aaacaactgt gatgactctc atgccttttt cgacagtagt accaacaaaa
    20641 gactctccag ccttatctgt tgttcctgtt tttagcccat caaaaccacc acggtaagca
    20701 ggcatacctt ctaacatgta gttggttgaa gtgattgtca tcccagcaaa agtagaagaa
    20761 ggttttttgg tgatttctaa gacttgtggg tattttttga tgaggttgcg agcaacgata
    20821 gcgacatcat aagcactaag cttattttcc tcatcttttt tagaacctgg gtaaatgtta
    20881 tcccctagag tttcattgtt aagacctgtc gtattgacaa cagtggcatc ctgaattccc
    20941 cattccaaga gttttgcccg catcatatcg acgaaatctt tttctgagcc agcaattttc
    21001 tcagctaggg caatagcggc gctgttggca ctagatacca gagttgcttc aagcaactct
    21061 tcgacagtat aattacgggc ctccatagga atattactgg cttcagaatt tgtcgtcaat
    21121 tgataaggat aatcagaaat atctacagga gtggagaggg taatacttcc gttttccaaa
    21181 gcttcataga ctagataaac agtaatcaat tttgttatgg aagcaatttc gacaggttgc
    21241 gttgcatcct tctcatagag aattttacca gtatttgcct caacagcaat cgcatgttta
    21301 gcggcaatgg taaaatcttg agcaacagca gtagaaacac cccctaaaag agagacagtt
    21361 aacaaagtta aaaatatttt tttcatagta gtcttattct atcataaaga aaaaaaatat
    21421 tcttgcttta ataattcatc tgttaagctt tttgaaaata tggtaaaata aagtgaggga
    21481 ggtaactcat gtttcgtaga aataaattat ttttttggac cacagaaatt ttactcttaa
    21541 ccatcatctt ttacctatgg agacagatgg gatctttgat taaccctttt gttagcgtgc
    21601 ttaatacaat tatgattcca tttttattag ggggctttct ttattatttg acaaacccta
    21661 ttgttacttt cttaaataaa gtctgtaaac tcaatcgttt gcttggtatt ttaattacct
    21721 tgtgtacttt ggtctgggga atggtcatag gtgttgtcta tctcttacct attttgatta
    21781 atcagttatc tagtttgatt atatctagtc aaactattta tagtcgagta caagacttaa
    21841 tcatagactt atctaattat cctgcgctcc agaatttgga tgtagaagct acaattcagc
    21901 agttaaactt atcctatgtt gatattcttc aaaatatcct aaatagcgta tcaaatagtg
    21961 tggggagcgt cttgtcagct cttatcagta ctgttttgat tttgattatg actccagttt
    22021 ttttggttta tttcttatta gatggacata aattcttgcc catgcttgaa agaacgattc
    22081 taaagaggga tcgcttgcat attgcaggct tattaaagaa tttaaatgcg acgattgctc
    22141 gctatattag tggagtttcg attgacgcaa tcattatagg ttgtttggct tatattggct
    22201 atagtattat tggtttaaaa tatgctttag tttttgccat tttttctggt gtagccaatt
    22261 taattcctta tgtggggcca agtattggtt tgattcctat gatcatcgca aatatattca
    22321 ctgatcccca tagactgctg attgcagtga tttatatgct tgttgttcag caggtagatg
    22381 gcaatatctt atatcctcga attgtaggaa gtgttatgaa ggttcatcca atcacgattt
    22441 tagttttact tttgttgtca agcaatatct atggtgtagt tggaatgatt gtcgcagtgc
    22501 caacctattc tatcttgaaa gaaatttcta agttcttatc ccgtttgtat gaaaatcata
    22561 aaataatgaa agaacgagaa agagaattag ctaagtaaaa gtcaggagaa ccctgatttt
    22621 tctttactgg aagtggcctt tagattagaa gactgaaaat aagttaaagt cttaaactaa
    22681 ttttcacagc taagaatagt agaagttaat ctgataaaaa tcgaaaaaac cagtggaatt
    22741 ccgtgtcagg gtaagttcca ctggttttca tagtctatta aagttcgaat gaaacctatt
    22801 tatagtatat tgaaactaga atagtacacc tctaattcta aaacattgtt agaaatcgat
    22861 ttgactgtcc tgatctattc gtcctattct tatttcattt tactatattt tggtgcaata
    22921 agtgaaaagt agtccgaata atataaggat tgattttata gtttttaaac tcaaatgaat
    22981 taaaataaag agagtacgaa aattctcatc tgaaagtatt ttagaataat tctcttcgtg
    23041 aatttcttca aaacagatag cttcatctta ggtatgtgtt aattggattt cgtaagctct
    23101 atttacaatc gtaaagttat gcactgaaaa agttgtagtt agtcttccag tttgctaaat
    23161 ttctcgaata gtatcttttt taggtatgtg atttcttttt gcatttttga gttagataag
    23221 gtataatggt tttattgtct tttggggtcg ttacggattc gacaggcatt atgaggcata
    23281 ttttgcgact cgtgtggcga cgtaaacgct cagttaaata taactgcaaa aaataacact
    23341 tcttacgctc tagctgccta aaaaccagca ggcgtgaccc gatttggatt gctcgtgttc
    23401 aatgacaggt cttattatta gcgagatacg attaagcctt gtctagcggc ttgataagag
    23461 attgatagac tcgcagtttc tagacttgag ttatgtgtcg aggggctgtt aaaataatac
    23521 ataacctatg gttgtagaca aatatgttgg caggtgtttg gacgtgggtt cgactcccac
    23581 cggctccatt attcctttgc attcttttgc attccttggt aaaacgttgt taaatcaacg
    23641 ttttttattt ttatctttgg tattcctttg cattcttttg ctaaaaaggg agtcacaaac
    23701 agaccctatt ttaaaaaaag gatagaaaaa aggatacaac atttgtcgca tcctaaaaat
    23761 aatctttttt cgacggaaga catgggattc gaacccacgc acgctattac acgcctaccg
    23821 cgtttccaac acggcctctt aagcctcttg agtaatcttc caatacttac tcaaatagtc
    23881 taccataaag gctcttatct tgcaataaaa attctagaaa taagaaaaat gatagatttt
    23941 gaaagaaaat gataaaaaat gcttgacttc aaaagaaagt atgatagaat gaatagtgta
    24001 aacgataaca ggaggtgatt cggtgttaaa aacagagcgg aagcaactga ttttagagga
    24061 gttaaatcaa catcatgtag tttctctaga aaaattagtt agtttgctag aaacgtcaga
    24121 atcaacggtt cgaagagact tggatgagtt ggaagcggaa aacaagcttc gtcgtgtgca
    24181 tggtggagca gaactccccc actccttaca ggaagaagaa accattcaag aaaaatcggt
    24241 caaaaacctt caagaaaaga agttgctggc tcagaaagca gcctctctca ttaaagaaaa
    24301 agatgtcatc tttatcgatg ctggaacaac aactgctttt ttgattcatg aattggtcaa
    24361 taagaatgtt acagttgtga ccaactccat tcaccatgcc gctcagttgg ttgaaaagca
    24421 gattccaact gtcatggttg gaggaaacgt caagacggcg acagatgcta gtatcggggg
    24481 cgttgctctt aaccagatta accaattgca ctttgaccgt gcctttatcg gaatgaatgg
    24541 tgttgacgat ggctattata cgactcctga tatggaggag ggagctgtga aaagagctat
    24601 tttggagaat gccaagcaga cctacgtctt ggtggattcg tcaaaaattg gacaaacttg
    24661 ctttgccaag gtagcaccac tcaaacgcgc tatcgttatc actagtcaag ggcatgagct
    24721 cttgcaggtt attaaggaga aaacggaggt aatagaagta tgatttatac agtcacactc
    24781 aatccatcca ttgactatat cgttcgtttg gaccaagtca aagttggtag tgtaaatcgt
    24841 atggacagtg atgataagtt tgctggtggg aaaggaatca atgtcagccg tgtcttgaaa
    24901 cgtttgaata taccaaatac agcgacggga tttatcggtg gctttactgg taaatttatc
    24961 acagatactt tagcagagga agaaatcgag acacgttttg tccaggtggc agaagatact
    25021 cgtatcaatg ttaaaatcaa agcagaccaa gaaacagaaa tcaacggaac gggtccaact
    25081 gttgaaccgg ttcagctaga agaattgaaa gctattttat ctagtctgac agcagaagat
    25141 acagttgtct ttgcaggttc aagtgctaaa aatctaggca atgttatcta taaggatttg
    25201 atttccttga cgcgccagac tggtgcgcaa gtggtctgtg actttgaagg acagacctta
    25261 attgatagtt tggactacca gcctcttctt gtaaaaccaa acaatcatga acttggagcg
    25321 atttttgggg ttaaactcga aagtttagat gaaattgaga aatacgctcg tgagttactg
    25381 gctaagggtg ctcaaaatgt tattatctct atggctggtg atggcgccct tcttgtcaca
    25441 tctgagggag cttacttcgc taaaccaatc aaaggaacag tcaaaaattc agttggagct
    25501 ggtgattcta tggttgctgg attcacaggt gaatttgtca aatcaaaaga cgcagtagaa
    25561 gccttcaaat ggggagtggc ttgcggaacg gcaactacct tctcagatga cttggcaacg
    25621 gcggaattta ttaaagaaac atatggaaaa gttgaggtag aaaaaagatg aaaattcaag
    25681 acctattgag aaaagatgtc atgttgctag atttgcaggc aactgaaaaa acagctgtca
    25741 tcgacgagat gattaaaaat ttgacagagc acggttatgt aacagatttt gaaacattta
    25801 aagaaggaat tttggcgcgt gaagctttga cttctactgg tttgggtgat ggaatcgcaa
    25861 tgcctcacag caaaaacgct gctgtcaaag aagcgacagt tctatttgct aagtcaaata
    25921 agggtgttga ctacgagagc ttggatggac aagcaactga cctcttcttc atgattgcag
    25981 ctccagaagg tgccaatgat actcacttgg cagccttggc agaattgtct caatacttga
    26041 tgaaagacgg ttttgcagac aaacttcgtc aagcaacatc tgcagaccaa gttatcgaac
    26101 tttttgacca agcttcagaa aaaactgagg aacttgttca agcacctgct aatgactctg
    26161 gtgactttat cgtagctgtt acagcttgta caacaggtat tgcccacact tacatggccc
    26221 aagaagccct tcaaaaagta gctgctgaaa tgggggttgg tatcaaggtc gaaaccaacg
    26281 gtgctagcgg tgttggaaat caactaactg cagaagatat ccgtaaggct aaagctatta
    26341 tcattgcagc agacaaggcc gttgaaatgg atcgatttga tggaaaacca ttgatcaatc
    26401 gtccagttgc tgacggtatc cgtaagacag aagagctaat taacttggct ctttcaggag
    26461 atactgaagt ctaccgtgcc gctaatggtg ccaaagctgc aacagcctct aacgaaaaac
    26521 aaagccttgg tggtgccttg tacaaacact tgatgagtgg tgtatctcaa atgttaccat
    26581 tcgttatcgg tggtggtatc atgattgccc ttgccttctt gattgacggt gctttgggtg
    26641 ttccaaatga aaaccttggc aatcttggtt cttaccatga gttagcttct atgttcatga
    26701 aaattggtgg agctgccttt ggtttgatgc ttccagtctt tgcgggttat gttgcctact
    26761 ctattgctga aaaaccgggt ttggtagcag gtttcgtggc tggtgctatt gccaaagaag
    26821 gttttgcctt tggtaaaatt ccttatgccg caggtggtga agcaacttca actcttgcag
    26881 gtgtctcatc tggtttccta ggtgcccttg ttggtggatt tatcgcaggt gccttggttc
    26941 ttgccatcaa gaaatacgtt aaagttcctc gttcactcga aggtgctaaa tcaatccttc
    27001 tattgccact tcttggaaca atcttgacag gatttgttat gctagctgtg aatatcccaa
    27061 tggctgcaat caacactgct atgaatgact tcctaggcgg tcttggagga ggttcagctg
    27121 tccttcttgg tatcgtcctt ggtggaatga tggctgttga catgggtgga ccagttaata
    27181 aagcagctta tgtctttggt acaggtacgc ttgcagcaac tgtttcttca ggtggttctg
    27241 tagccatggc agcagttatg gctggaggaa tggtgccacc acttgcaatc tttgtcgcaa
    27301 ctcttctttt caaagataaa tttactaagg aagaacgtaa ctctggtttg acaaacatca
    27361 tcatgggctt gtcatttatc actgagggag cgattccatt tggtgccgct gacccagctc
    27421 gtgcgattcc aagcttcatc cttggttcag cagtagcagg tggactcgtt ggtcttactg
    27481 gtatcaaact catggcgcca cacggaggaa tcttcgttat cgcccttact tcaaatgctc
    27541 tcctttacct cgtttctgtc ttggtaggag caatcgtaag tggtgtggtt tatggttacc
    27601 tacgcaaacc acaagcataa aaaatagaaa aatgaaaaga ttggaccgtt tggtgcagtc
    27661 tttttctctt cccgaaatgc ctgtgaaata tggtataata gaagaatggc aaacaagaat
    27721 acaagtacaa caagacggag accgtctaaa gcagaactgg aaagaaaaga agcgattcaa
    27781 cgaatgttga tttcgttagg aattgcgatt ttattgattt tcgcagcctt caaattaggg
    27841 gctgcaggta taacccttta taatttaatt cgcttgctag tgggtagcct agcttatctg
    27901 gcgatattcg gcctattaat ctatctcttc tttttcaagt ggatacgaaa acaggaagga
    27961 ctcttatctg gctttttcac catatttgct ggcttactct tgatttttga ggcctacttg
    28021 gtttggaaat atggtttgga caagtccgtt ctaaaaggga ccatggctca ggttgtgaca
    28081 gatctgactg gttttcgaac gactagcttt gctggagggg gcttgatcgg ggtcgctctt
    28141 tatattccaa cagcctttct cttttcaaat atcggaactt actttattgg ttctatcttg
    28201 attttagtgg gttctctcct agtcagccct tggtctgttt acgatattgc tgaatttttc
    28261 agtagaggct ttgccaaatg gtgggaaggg cacgagcgtc gaaaagagga acgctttgtc
    28321 aaacaagaag aaaaagctcg ccaaaaggct gagaaagagg ctagattaga acaagaagag
    28381 actgaaaaag ccttactcga tttgcctcct gttgatatgg aaacgggtga aattctgaca
    28441 gaggaagctg ttcaaaatct tccacctatt ccagaagaaa agtgggtgga accagaaatc
    28501 atcctgcctc aagctgaact taaattccct gaacaggaag atgactcaga tgacgaagat
    28561 gttcaggtcg atttttcagc caaagaagcc cttgaataca aacttccaag cttacaactc
    28621 tttgcaccag ataaaccaaa agatcagtct aaagagaaga aaattgtcag agaaaatatc
    28681 aaaatcttag aagcaacctt tgctagcttt ggtattaagg taacagttga acgggccgaa
    28741 attgggccat cagtgaccaa gtatgaagtc aagccggctg ttggtgtaag ggtcaaccgc
    28801 atttccaatc tatcagatga cctcgctcta gccttggctg ccaaagatgt ccggattgaa
    28861 gcaccaatcc ctgggaaatc cctaatcgga attgaagtgc ccaactccga tattgccact
    28921 gtatctttcc gagaactatg ggaacaatcg caaacgaaag cagaaaattt cttggaaatt
    28981 cctttaggga aggctgttaa tggaaccgca agagcttttg acctttctaa aatgccccac
    29041 ttgctagttg caggttcaac gggttcaggg aagtcagtag cagttaacgg cattattgct
    29101 agcattctca tgaaggcgag accagatcaa gttaaattta tgatggtcga tcccaagatg
    29161 gttgagttat ctgtttacaa tgatattccc cacctcttga ttccagtcgt gaccaatcca
    29221 cgcaaagcca gcaaggctct gcaaaaggtt gtggatgaaa tggaaaaccg ttatgaactc
    29281 tttgccaagg tgggagttcg gaatattgca ggttttaatg ccaaggtaga agagttcaat
    29341 tcccagtctg agtacaagca aattccgcta ccattcattg tcgtgattgt ggatgagttg
    29401 gctgacctca tgatggtggc cagcaaggaa gtggaagatg ctatcatccg tcttgggcag
    29461 aaggcgcgtg ctgcaggtat ccacatgatt cttgcaactc agcgtccatc tgttgatgtc
    29521 atctctggtt tgattaaggc caatgttcca tctcgtgtag catttgcggt ttcatcagga
    29581 acagactccc gtacgatttt ggatgaaaat ggagcagaaa aacttcttgg tcgaggagac
    29641 atgctcttta aaccgattga tgaaaatcat ccagttcgtc tccaaggctc ctttatctcg
    29701 gatgacgatg ttgagcgcat tgtgaacttc atcaagactc aggcagatgc agactacgat
    29761 gagagttttg atccaggtga ggtttctgaa aatgaaggag aattttcgga tggagatgct
    29821 ggtggtgatc cgctttttga agaagctaag tctttggtta tcgaaacaca gaaagccagt
    29881 gcgtctatga ttcagcgtcg tttatcagtt ggatttaacc gtgcgacccg tctcatggaa
    29941 gaactggaga tagcaggtgt catcggtcca gctgaaggta ccaaacctcg aaaagtgtta
    30001 caacaataaa aaaatagctt ctttccaagt ttggagggaa gctatttttc tggctattga
    30061 ttacttttat actcttcgca aatctcttca aaccacgtca gcttcgcctt gccgtactca
    30121 agtactgtct acggctagct tcctagtttg ctctttgatt ttcattgagt attattttct
    30181 gaagttggag tattgggctg tttttcattt tcagtggcag gtttacttgt agcaggtgta
    30241 gtagagtcct gagttgctgt tttctgatct tcttttttct cttccttgac gctagatttt
    30301 ggcgtttctt cttgttgtgt tttttcttga gaagtgttat tttccttatt tggagtagta
    30361 ttttcctgag gggattcttt ttgaatttct ttgacaaagg ttgtcgtctg gcttgtcgta
    30421 ggttcttttt tagtattttt attattatta tccaaggcgt tcatgatcgt gatacccgcg
    30481 gtaatcaaac caaggatact accgatagta gtaatggttt tttgaaaaac agtaaagcct
    30541 tttttgatat gttctgtttt cggttttgaa gttctacgat agttagacat acattctctc
    30601 ctttgattat gatttattat actctgtttc tttaaaaaaa tcttaaaaaa agagaaattg
    30661 ccctttcttg tcgcaggctc cgtttcatga tacaatagaa ggagtgattt tagaaagcgt
    30721 gagaaacatg atttactttg ataattcggc gacgaccagg ccctatccag aagcccttga
    30781 aacctatatg caggtggctt caaaaatttt aggaaatcca tctagtctcc atcgtttggg
    30841 agaccaggca acacgaattt tagatgcttc ccgtcaacag attgcagatt taatcggtaa
    30901 gaaaagtgat gaaatcttct ttacatctgg tgggacagaa ggggataact ggatcatcaa
    30961 gggagtagca tttgaaaaag cccagtttgg caagcacatc atcgtatcag ccattgaaca
    31021 tccagcagtt aaggaatcag ccctctggtt gaaagctcaa ggttttgaag tggattttgc
    31081 tccagttgat aacaaaggat ttgtggatgt tgaggcgcta gaagatttga taagacctga
    31141 tacgaccctc gtttccatca tggctgtgaa caatgaaatc ggctctatcc aacctattga
    31201 ggctatttca gaattcttgg cagacaagcc aactatttcc ttccacgttg atgcggttca
    31261 ggcgcttgcc aagattccga ctgaaaagta tctgacagaa cgagtggatt tcgcgacttt
    31321 ctctggtcac aagttccacg gaatccgtgg tgttggtttt atctatatca agtctggcaa
    31381 gaagattacg cctcttttaa caggtggtgg tcaggaacgt gattaccgtt cgacaactga
    31441 aaatgtggca ggaattgcag cgaccgctaa ggctctccgt ttatctatgg aaaagctaga
    31501 tatctttagg agcaagactg ggcagatgaa ggcagtgatt cgtcaagcac ttctggacta
    31561 tccggatata tttgtctttt cagatgagga agacttcgcc cctcatattc tgacttttgg
    31621 aatcaagggt gttcgtggtg aggtcattgt tcacgccttt gaagactatg atattttcat
    31681 ctcaacgacc tcggcttgtt cgtccaaggc tgggaaacca gccggaaccc tgattgctat
    31741 gggagtggac aaggataagg ctcagtcagc tgtgcgtctt agtctagacc ttgaaaatga
    31801 tatgagtcag gtcgagcagt tcttgaccaa gctaaaatta atttacaatc aaactagaaa
    31861 agtaagatag gagcattcat gcagtattca gaaattatga ttcgctacgg tgagctgtca
    31921 accaagggca aaaatcgtat gcgtttcatc aataaacttc gcaataatat ttcagacgtt
    31981 ttgtctatct atccccaagt taaggtaaca gcagatcgcg accgtgccca cgcttacctc
    32041 aatggagcag attacacagc agtagcagaa tcgctcaaac aagtatttgg aattcaaaac
    32101 ttttcccctg tttataaggt tgaaaaatct gtagaagttc tgaagtctgc tgtccaagag
    32161 attatgcagg acatctacaa ggaaggcatg acctttaaaa tctctagcaa gcgtagcgac
    32221 cacacctttg aattggacag tcgtgaactc aaccaaacgc ttggaggggc tgtattcgaa
    32281 gccattccaa acgtacaagc tcaaatgaaa agtcctgaca tcaatcttca ggtggagata
    32341 cgtgaagaag cagcctatct ttcttatgaa accgttcgag gggcaggtgg attaccagtg
    32401 ggaacttctg gtaagggcat gctcatgttg tcagggggaa tcgattcccc tgtagctggc
    32461 tatctagcgc ttaaacgagg ggtagatata gaggcagttc actttgccag cccaccttac
    32521 acgagtcctg gtgctcttaa aaaagcccaa gatttgaccc gtaaattaac caaatttggg
    32581 ggaaatatcc agtttatcga agttcctttt acagagattc aagaggaaat caaagccaaa
    32641 gcgccagaag cctaccttat gaccttgacg cgtcgtttta tgatgcgtat tactgaccgt
    32701 attcgtgagg tacgaaatgg tttagttatc atcaatgggg aaagtctagg tcaagtagcc
    32761 agccaaaccc ttgaaagtat gaaggctatc aatgctgtta ccaacactcc catcattcgt
    32821 cctgtggtta ccatggacaa gttggaaatc attgacatcg cccaggaaat cgataccttt
    32881 gacatttcaa tccaaccgtt tgaagactgt tgtactattt ttgcaccaga tcgtccaaaa
    32941 acaaatccta aaattaagaa tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg
    33001 gttgagcgag cagtggctgg aatcatgatt actgaaatca cacctcaagc cgaaaaagat
    33061 gaagttgatg acttgattga caatctgctc taattcagaa aatccaaaag aatagcgaaa
    33121 atcagtaaaa aaagttagtt ttttctctaa aaacaggtaa aaaactaact ttttttattt
    33181 ttatgatata atgatataaa attttgaata tagagagttt tctgacaatg aatcaatcct
    33241 acttttatct aaaaatgaaa gaacacaaac tcaaggttcc ttatacaggt aaggagcgcc
    33301 gtgtacgtat tcttcttcct aaagattatg agaaagatac agaccgttcc tatcctgttg
    33361 tatactttca tgacgggcaa aatgttttta atagcaaaga gtctttcatt ggacattcat
    33421 ggaagattat cccagctatc aaacgaaatc cggatatcag tcgcatgatt gtcgttgcta
    33481 ttgacaatga tggtatgggg aggatgaatg agtatgcggc ttggaagttc caagaatctc
    33541 ctatcccaga gcagcagttt ggtggtaagg gtgtggagta tgctgagttt gtcatggagg
    33601 tggtcaagcc ttttatcaag cacaaaacag gttggtttga tggcatgatg acgacaggtt
    33661 gctctatggg agcctatcat gcactcaatt tcttcctcca gcatccagat gtctttacca
    33721 aagtgattgc tctcagtggt gtttacgacg cacgtttctt tgtcggcgat tactacaacg
    33781 atgatgctat ttaccaaaac tcgccagtag attatatttg gaaccaaaac gatggctggt
    33841 ttattgaccg ttaccgtcag gcagagattg tgctgtgtac ggggcttgga gcctgggaac
    33901 aagatggttt accatccttt tacaagctca aagaagcctt tgaccagaaa caaattccag
    33961 cctggtttgc tgaatgggga catgatgtcg cccacgactg ggaatggtgg cgtaaacaaa
    34021 tgccttattt cctcggtaat ctctatttat aaaaggagtt acctatgaat taccttgtta
    34081 tttctcccta ctatccacaa aactttcaac agtttaccat cgaactagct aataaaggca
    34141 tcacagtctt gggaattggt caagagtctt acgagcaatt ggatgagccc ttgcgcaata
    34201 gcttgaccga gtattttcgt gttgataatc ttgagaacat agatgaagtc aaacgtgcag
    34261 ttgcttttct cttttataaa catggtccaa ttgaccgcat cgagtctcac aatgaatact
    34321 ggcttgagct agacgcaaca ctcagagaac aattcaatgt ttttggtgcc aaaccagagg
    34381 atctcaaaaa gacgaaatat aagtctgaaa tgaagaaact tttcaaaaaa gcaggtgttc
    34441 ctgtggtacc tggagctgtt atcaagacgg aagcagatgt tgatcaagca gtgaaagaaa
    34501 tcggtcttcc aatgattgcc aaacctgata atggagtggg agcagccgca acctttaaac
    34561 ttgagacaga agacgatatc aatcacttca agcaagaatg ggaccattca accctttatt
    34621 tctttgaaaa atttgtcact tccagcgaaa tctgtacctt tgacgggctc gtggacaagg
    34681 atggaaagat tgtcttctca acaacctttg actacgccta tacaccgctt gacctcatga
    34741 tttataagat ggacaattct tattatgtgc tcaaggatat ggatcctaaa ctgcgcaagt
    34801 atggggaagc aattgtcaaa gaatttggta tgaaagaacg gtttttccat attgagttct
    34861 tccgtgaggg ggacgattat attaccatcg agtacaataa ccgccctgca ggtggtttta
    34921 ccattgatgt ttataacttt gctcattcct tggaccttta tcgtggctat gcagctattg
    34981 tcgcaggaga ggagttcccg gcgtcagact ttgaaactca gtattgtttg gctacttctc
    35041 gccgtgcaaa tgctcactat gtttattcag aagaggattt gcttgccaaa tatagccagc
    35101 agttcaaggt taaaaaagtc atgccagctg ccttcgcgga acttcaagga gattacctgt
    35161 atatgctgac aactccgagt cgacaagaaa tggatcagat gattgctgat ttcggacaac
    35221 gtcaagaata agaactatcg gattaaggaa attcactccc ttaatccttt tgttttgtct
    35281 ggtaaaaaat aagagcatcc taacaaggta gctatcataa aacttgttcg ataactattt
    35341 gaagcaggat taggtggcta gaaattgaat tttaacattt caatttagtc atagtattgt
    35401 gttttcgtat ccttaaatca gctaaaagga tccatgacga cacctatacg atatagtttt
    35461 caggatacca aaccagtcta ttaatactca atgaaaatca aagagcaaac taggaagcta
    35521 gccgcaggtt gctcaaaaca ctgttttgag gttgtggata gaactgacag agtcagtatc
    35581 atatacctac ggcaaggtga agctgacgtg gtttgaagag attttcgaag agtataaaat
    35641 attcaggtga cgcatagata tagttaattg aagctttgtt tgaaatctga taaaataatg
    35701 atattactaa gttttaaaaa ctaaagaaaa gggaagatat gattacaggc gaattaaaaa
    35761 ataaaatcga tcagctgtgg gaaattcttt ggacagaagg aaacgcaaat cctttaacaa
    35821 atattgaaca gttgacttat ctcttattta tgaaagattt ggatagtgtc gagcttggac
    35881 gtgaaagtga tgctgaattt ctagggattc cttatgaggg agtttttcca aaagataaac
    35941 ctgaataccg ttggtcaact tttaaaaata taggagatgc tcaggaagtt tatcgtttaa
    36001 tgactcagga gatttttccg tttattaaaa atctcaaggg ggatacagat gatacagcct
    36061 tttcacgata tatgcgagaa gctatttttc aaataaataa acctgctacg cttcaaaagg
    36121 caatttctat cttagatgtt tttccaacta ggggattaga tgtagatttt gataatgaca
    36181 aacaaagtat tactgatatc ggagatatct atgaatatct gttatcaaaa ttgtcgaccg
    36241 caggtaaaaa tggacagttc cgtacacctc gtcacatcat cgatatgatg gttgagttga
    36301 tgcaaccgac tatcaaagat atcatctcag atcccgctat gggttctgct ggcttcttag
    36361 tatctgctag ccgttactta aagcgtaaga aagatgaatg ggaaaccaat acagataata
    36421 tcaatcattt tcataatcag atgtttcatg gaaatgatac ggatacgact atgttgagac
    36481 ttggggcgat gaacatgatg ctacatggag tagaaaatcc acaaatcagt taccttgact
    36541 cgctgtctca agataatgaa gaagccgata aatatacttt ggttttagca aatcctcctt
    36601 ttaagggctc acttgactac aattcaacct ctaatgacct tcttgcaacc gtaaaaacca
    36661 aaaaaacaga attactcttt ctttctcttt tcttgcgaac tttaaaacca ggtggacgag
    36721 cagcagttat cgtacctgat ggtgtccttt ttggttcgtc taaagctcat aaaggaattc
    36781 gtcaggaaat tgtagagaat cataagcttg atgctgtaat ctcaatgcct agtggtgtgt
    36841 tcaagcctta tgctggagtt tcaactgcca ttctcatctt tacaaaaact ggtaatggtg
    36901 gtactgacaa agtctggttt tacgatatga aagcggatgg tttaagtttg gatgataagc
    36961 gacaaccgat tagcgacaat gatattccag atattatcga acgctttcat catcttgaaa
    37021 aagaagcaga acgtcagaga acggatcaat ctttctttgt tccagttgct gagataaagg
    37081 aaaatgatta tgatttgtct atcaataaat ataaagagat tgagtatgaa aaagttgagt
    37141 atgaaccaac agaggtcatc ttaaagaaaa tcaatgattt agaaaaagaa attcaagctg
    37201 gcttggctga attagaaaaa ttactcaagt agggaggtgg ctgtatgaaa aaagtgaagt
    37261 tgggggaagt cttatctcta aaaaaaggca agaaagccac tgtacttgct gaacaaacaa
    37321 ctctaagcca acgttatatt caaatagatg atttaagaaa taataataat ttaaaattca
    37381 ctgaaagttt aaatatgact gaagcactcc cagatgatat tctgatagca tgggatggag
    37441 ctaatgcagg aacagttggt tatggattat cgggagctgt tggtagtaca attacggtct
    37501 taaaaaagaa tgagcgatac aaagaaaaaa ttatatcaga ttacttggga gtctttttgg
    37561 aaagtaaatc gcagtattta cgagaacatt caacaggtgc aacaattcct catttaaaca
    37621 agaatatatt acttgattta caattagaat tgctaggtat cgaagaacaa gagaacatta
    37681 tctgtattct taatacgatt aaagggctta ttactaaaag aaaattgcag ttagatgaac
    37741 taaacttgct cg
//
LOCUS       DAVBNN010000017        34125 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBNN010000017 DAVBNN010000000
VERSION     DAVBNN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34125
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.017"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(90..1076)
                     /locus_tag="VQ847_000901"
     CDS             complement(90..1076)
                     /locus_tag="VQ847_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3050256.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1086..1886)
                     /locus_tag="VQ847_000902"
     CDS             complement(1086..1886)
                     /locus_tag="VQ847_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3050257.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2147..2989)
                     /locus_tag="VQ847_000903"
     CDS             complement(2147..2989)
                     /locus_tag="VQ847_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3050258.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(2991..4283)
                     /locus_tag="VQ847_000904"
     CDS             complement(2991..4283)
                     /locus_tag="VQ847_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3050259.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4394..5665)
                     /locus_tag="VQ847_000905"
     CDS             complement(4394..5665)
                     /locus_tag="VQ847_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3050260.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6215..7732
                     /gene="malQ"
                     /locus_tag="VQ847_000906"
     CDS             6215..7732
                     /gene="malQ"
                     /locus_tag="VQ847_000906"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3050261.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLGASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7758..10016
                     /gene="glgP"
                     /locus_tag="VQ847_000907"
     CDS             7758..10016
                     /gene="glgP"
                     /locus_tag="VQ847_000907"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3050262.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKIDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11061..11633)
                     /locus_tag="VQ847_000908"
     CDS             complement(11061..11633)
                     /locus_tag="VQ847_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050263.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGNWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12256..13104)
                     /locus_tag="VQ847_000909"
     CDS             complement(12256..13104)
                     /locus_tag="VQ847_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3050264.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13256..13534
                     /locus_tag="VQ847_000910"
     CDS             13256..13534
                     /locus_tag="VQ847_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050265.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13536..15599
                     /locus_tag="VQ847_000911"
     CDS             13536..15599
                     /locus_tag="VQ847_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3050266.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRLLQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15677..16933)
                     /locus_tag="VQ847_000912"
     CDS             complement(15677..16933)
                     /locus_tag="VQ847_000912"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3050267.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17075..19540
                     /locus_tag="VQ847_000913"
     CDS             17075..19540
                     /locus_tag="VQ847_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3050268.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19605..20516
                     /locus_tag="VQ847_000914"
     CDS             19605..20516
                     /locus_tag="VQ847_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3050269.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20746..21444
                     /gene="dapD"
                     /locus_tag="VQ847_000915"
     CDS             20746..21444
                     /gene="dapD"
                     /locus_tag="VQ847_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3050270.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21512..22642
                     /locus_tag="VQ847_000916"
     CDS             21512..22642
                     /locus_tag="VQ847_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3050271.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22654..23193
                     /locus_tag="VQ847_000917"
     CDS             22654..23193
                     /locus_tag="VQ847_000917"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3050272.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILHHPVYQEAKVI
                     ATYLSFPHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23177..23854
                     /locus_tag="VQ847_000918"
     CDS             23177..23854
                     /locus_tag="VQ847_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3050273.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(23926..24825)
                     /gene="galU"
                     /locus_tag="VQ847_000919"
     CDS             complement(23926..24825)
                     /gene="galU"
                     /locus_tag="VQ847_000919"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3050274.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24847..25863)
                     /locus_tag="VQ847_000920"
     CDS             complement(24847..25863)
                     /locus_tag="VQ847_000920"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3050275.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26075..26408
                     /locus_tag="VQ847_000921"
                     /pseudo
     CDS             26075..26408
                     /locus_tag="VQ847_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(26630..27055)
                     /locus_tag="VQ847_000922"
     CDS             complement(26630..27055)
                     /locus_tag="VQ847_000922"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050276.1"
                     /translation="MTNLSSVDSEELFQFYREQRNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKVLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(27131..27781)
                     /gene="phoU"
                     /locus_tag="VQ847_000923"
     CDS             complement(27131..27781)
                     /gene="phoU"
                     /locus_tag="VQ847_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3050277.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27796..28548)
                     /gene="pstB"
                     /locus_tag="VQ847_000924"
     CDS             complement(27796..28548)
                     /gene="pstB"
                     /locus_tag="VQ847_000924"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3050278.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28550..29365)
                     /gene="pstA"
                     /locus_tag="VQ847_000925"
     CDS             complement(28550..29365)
                     /gene="pstA"
                     /locus_tag="VQ847_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3050279.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29358..30221)
                     /gene="pstC"
                     /locus_tag="VQ847_000926"
     CDS             complement(29358..30221)
                     /gene="pstC"
                     /locus_tag="VQ847_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3050280.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30339..31214)
                     /locus_tag="VQ847_000927"
     CDS             complement(30339..31214)
                     /locus_tag="VQ847_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3050281.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31381..32712)
                     /locus_tag="VQ847_000928"
     CDS             complement(31381..32712)
                     /locus_tag="VQ847_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3050282.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32713..33420)
                     /locus_tag="VQ847_000929"
     CDS             complement(32713..33420)
                     /locus_tag="VQ847_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3050283.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33504..33989)
                     /locus_tag="VQ847_000930"
     CDS             complement(33504..33989)
                     /locus_tag="VQ847_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3050284.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            33975..34125
                     /locus_tag="VQ847_000931"
                     /pseudo
     CDS             33975..34125
                     /locus_tag="VQ847_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        10048 a         6433 c         7317 g        10327 t
ORIGIN      
        1 aatcttccca cattaaaacg catagtatca agttttttca atacctgata gtatgcgttt
       61 ttgcttttaa cgactttttg tccagtctct tatttttcga taattttgtg ggcgatcaat
      121 tgacggtaac aaatttgttt attgttttta ttatcattaa taatctggag aatagtttca
      181 agggaaacac gaccaagctc taaactattg atatcgacat aggctgccaa gttgagcttg
      241 ggattaaccg agtcaaagct gagaacaggg acatccagct ggtgtttggc aatatagtta
      301 caaacacctt cagctaggag gctatcggtt gtgatgatag catcaatttg tggatcgtgc
      361 ttgaataatc gcttgctaaa tttatagccc ttttcttcca gaaactcgtc ggcaaagtag
      421 atgcgattgt tgtcagtggt aagtttgtaa tgtttaagcg cctgttcata gcctgttaaa
      481 cggtctttgg tcacgaagag ctttttactt cctccgataa aggcaatgcg tttgcagcct
      541 tttttgatga aatattcagt cgcatcaaaa ccagcttgaa cattgtcgtt gtcgacaagt
      601 gggatgaaag gagatagaga tttacctaag ataaggaagg ggaactgttc ttctgcgacg
      661 agttttacga gagggtcttc ttcttgggca tagagaaaga ttagcccatc tacacgcttg
      721 ccgtagacca tttgtgaaat agcgttgaga cgctccttct catctttccc tgttgctatc
      781 tgaatggcat agtggttttc agatgcgact tgagagatgc cacgtagaac cgatggaaag
      841 aaaggattct ggtagaaggc gtctgagtca tcaggaagaa ctaatccgat aacctgagta
      901 tagctgctta ccaagctacg agcgttgagg tttgggtggt agttgagttc cttcatagct
      961 ttgcgaacgc gtttttttgt ttcgtcgcta atggttgatt tattttgaat aacacgggtt
     1021 acggttgaag gcgaaacacc agcagccttg gccacgtctt taatcgtaac gggcataaaa
     1081 atctcctatt tatggtaatt tggatcacgg aaatgtgttt tataaaagat agtgaccaga
     1141 tacagaacaa aaagaatatt ttgtacagta atcagggttg tcatattttg gccaaataat
     1201 cccaaaataa gtgtaatcag agtcggcaat cctaaacagt tcaagataaa gtgatagcac
     1261 tctttaaagg ttctaaatga aaagaggcgt gatttcttag tgatataaag gagaagacta
     1321 gctcctagag agacgataaa gaaattcaaa ccaaagagga agctcgcacc gagaactagg
     1381 aagaggctga tatagacacg attttgttgg taccagtctt tagaaattgc ttgggtcaag
     1441 ctgtctttgc ttttgaaact ctcagtctga atggctcggt aagagatgcg ggtcagttcc
     1501 ttgctttcct tgctgatgac tagctcattt gtatcgaaat gcagttgcaa gttcttaggt
     1561 aattccttga tttgacttgg accaatcaca acagaagagg cttgactaac tgttccagta
     1621 taagttaatg tgccatcgac aattgtagca tgttcagaga gatcctggac aacctcattt
     1681 gtcagaggtt catagacatt atcgataaaa gtttctagcg gataggtctc ctgggagctg
     1741 ttttggatag caatgggtac catagacaag ctgataagga agatactggt aaagagaagt
     1801 tgaaaccagt tgagcccgaa acgtttggac aggggcttac gaaaccccaa aatacttgaa
     1861 aaaaaggaaa atggatatgg aagcataggt atctttctaa aaggtgtttt ctatataagt
     1921 attattatat agagaaatgc gctttatttc aagtctagga gaaaaattgc ttgctacaag
     1981 gatattattt acagtgacaa tcgctaatag tcaatgaaaa tcaaagtgca aaccaggaag
     2041 ctagctgcag gttgctcaaa gcacaacttt gaggttggag ataaagctga cgtggtttga
     2101 agagattttc gaagagtata aaatgaaaaa gggtggcggg gataaattat cccttgtcgc
     2161 caccacttgt aagtcctgaa acaaagttct tttgtaggaa gaagaagaga atacagattg
     2221 gaagggcgat gaggatagca cctgctgaga agtaggcaat cttcaagttt ttcgcattgt
     2281 taacgaaggt ttggagacct acggcaacag taaagtattc tttctcacga agcaagaaac
     2341 tagagaggat gtagtccccg aaaggtccca tgaaggccca gagagcttgt acggcaacca
     2401 ttgggcgaac aagtggaaga acaatttgcc agaagcggcg gaagtgtcct gcaccgtcta
     2461 gttttgcaga ttcgtctaaa gacattggca ctgtatcgaa gtagcctttc atgagccaag
     2521 cattcatcgg gataccacca ccaacgtaga ggaagatgag gaaccagttg tggttaaggg
     2581 cgttcaacat aagcgccata acgaagaagg ctgtcaaagc ggccatagtt ggcaccattt
     2641 ggatgatcaa gaagaagacc aaactttgtt tacgagccaa gaagttgtaa cggctgtaag
     2701 cataaccagc aagtacgatg atacttgttt gaacagccat ggtaattaag gcgataatca
     2761 aagtgttgag gtaccaagta ccgtacaagg tttcagtgaa gaggccttta aagttatcaa
     2821 aattgaggtc gatattagta tctagtttaa aggctgagac gttacctgct ttaaaggctg
     2881 acataatggt aatcaacagt ggatagataa ttacaattga tagaccaatc aggtaaaggt
     2941 aagtaaggct ttgagtcagt ctacgtttga gtttaattga gttattcatc ttagacgtcc
     3001 tccatatcaa atgcgtgtag tttcttgaat gcgatcatag agattgagat gacaatgata
     3061 gagataatca aggtaacagc tgccgccatt gagtattgag gagatgtacc tgttgtcaaa
     3121 cggtagatcc atgagatcaa gatatcggtt gaaccagctc cacctccgac actaccaggt
     3181 cctccaccat tgaagaggta catgatagag aagttgttaa agttgaaggt gtattggcta
     3241 atcaaagtag gtgccgcaac agccaaaatc attgggaaag tgatgttgcg gaatttttgc
     3301 caagcgttgg caccgtcaat ataagctgct tcgtaaaggt cgttaggaat agattgcaag
     3361 atacccaaag tcaaaacgta gatgtatggg aatccgagcc aaccttgcat cataatcaag
     3421 gcaatcttag tccaagttgg gtctgttttc caaggaataa gagctccatc aaggaaagga
     3481 aggaatttag ccaagattgg caatacttga gtgttgatag caccgacact atcgttaaac
     3541 atgtttgaga atgtcaagat agtgatgaag gctgggacag cccaaggaag aaggaaaata
     3601 acaccaaaga tacgttttcc tttgataaat ggttggttgg caatgatagc tgtgaagata
     3661 ccaattacga tttgtaaagt agaagctgcc aaagcccaaa tgatagtcca agaaagaaca
     3721 gaaccaaagg cagaacggaa ggtactcaag ctccaaatgt ttgtaaagtt ggtcaaacca
     3781 acccagtcca acaacttgtt tggtggcaag tgttggaagt cgtagttggt aaaggcgatc
     3841 atcaaggtta cgataactgg gaagataatc gcgaaggtca tggcaacata agatggaatg
     3901 atcaagaggt aagggaagcc attttcataa atccctttga tcatgtcttt gagtgtgcgt
     3961 ggaactggaa ttccattgtt aatgcgtttt gcaatcgtat gtgcatcttt gatatttgag
     4021 aaataaaaga gtacataaac gattacaaag attagatgga aggcaccacg aatcagcata
     4081 aagagggaat tatcacgacc tggtttgtca ccaagagtga tgaggttgct caattcaggg
     4141 gttgcaagtg ctaggaagta aaggacaaat acgatggtta caccaaggaa gataaaacct
     4201 ttggcttttt gtttattgta aatctgtcct aacccaggaa tgatagacag cagggctgct
     4261 ttactaggtt gttgcttttc catattaact cctttcatag gatactactt ttttataaga
     4321 aagctaaatt atttgtgtct ctattgataa attcaaaggg ggatttgatt tccacccccc
     4381 ttgaacaaat tttttattca ccaaattttt gtttgattgt ttctttgatc aatgttacag
     4441 catcgttagc agctgtttta gcatcttttt gaccacttac agcatcaaag agcatatttt
     4501 tcgctggatc ccaaactgca gacatttgag agatgtttgg cagtggttga gtgttcttga
     4561 actgtttgat aacagctgtt gtcaactcat cgtttttacc ttcagcgtat gaacgagcct
     4621 cagtattagc tgggatttcg ttagtcttat catataatac tttttgttgt tcagttgcaa
     4681 caaggaagtc tacaaatttt tgagaagctt caaggttctt aacggcttga ggaatgaccc
     4741 aagctttacc accaccgaat gcagcatatt cttttccatt tggaagagtt gggatagttg
     4801 caactccgta gtttacttta gcatctttaa aggcttgagc tttccaaggt ccgtcgatga
     4861 tagcagctgt tttaccttct tggaattgag tttggattaa gtttccagca ccttctgtat
     4921 cttgcatacc tttaggccat ttttcgtacc aagatttagc gtagttgata cctgcgatag
     4981 aaccgtcgtt tgcaagaccg atgtctttag cgtctttacc gttttggcca aagacgtaag
     5041 caccgttacc ggcaagaagt ccatatgtat agtagaagtt tgtccagtca gctaggaagg
     5101 cagtagtttt accatcttca ccagcgaatg cgtatttgct atctttagca aggttttcca
     5161 agtcagcaaa tgtttttgga gcatctttca ccaagtcttt gttgtagtac ataacaagtg
     5221 actcgataac ggcaggagca ccgtaaactt taccattagc agctgttaca agagatttag
     5281 ttgtgtcgtc tgttttagca ccatcgctca atttcacttc tgaaagttgt ccgtcagaac
     5341 caaggctacc tacacggtcg tatggagcca tcataacatc agggacatta ccagattggt
     5401 tgtcaagaga aagtttatca agacctccta gagcatcacc agttttaaga gtgactttta
     5461 ctccagcttc tttttcataa gctttagcaa cctcttcaat atagctctta tatccctcgt
     5521 ctacatatac agtgagttct ttgacttcag atgaaccaga atcagcaggc ttatcagcag
     5581 ttttgcttcc gcaagctacc aaaagcaagc tagcaagtgt aacagttcca agcaccgcag
     5641 tgctcttcat aaatttagat gacatagtgt attcctccca aagaatagca agttttattg
     5701 ataaggaaac gcaaacgttt tcctttatga gcttagtata gcacaaatag aaaacggttg
     5761 caagtatttt ttgtaaaaat tttaaaaaat ttttaagctt gatttgatag cataattttg
     5821 cattttaata gaagaaaagt atgaaataga taagaataca gtatttttaa taaaaatata
     5881 tggaatctgt ctaaagaggg aaaccaggag gggctacctc cctgtttcta atccctatct
     5941 attttctata gacgtttgtg ctttgttgca tataaattca agctccctaa ggaggttttg
     6001 tactttgtag actgtctcgt gagagtcaaa ctttaggatt agatagtttt aagttatctt
     6061 tgctaaaatg agttagtctc cttaaaaata atcaaaaaag ttttttaaaa acgcttgcaa
     6121 ttatgcttga aaaggagtat acttataagt aacgcaaacg tttgcgtctg caaaatacgc
     6181 aacgttccat tattttaaca cacgaggtgc tattatgaaa aaacgtcaaa gtggtgtgtt
     6241 gatgcacatc tcttctcttc caggagctta cggaatcgga tcatttggtc aaagtgctta
     6301 cgacttcgtt gatttcttgg tccgtacaaa acaacgttac tggcaaatcc ttccattagg
     6361 agcaactagt tacggggatt ctccttacca atctttctca gccttcgcag gaaacactca
     6421 ttttatcgat ttagatatct tggtggagca aggtttgttg ggagcgagtg accttgaagg
     6481 agttgacttt ggtagcgatg cgtctgaagt tgactatgct aaaatctact atgcacgtcg
     6541 tcctctttta gaaaaagcgg tgaaacgttt ctttgaagtc ggagatgtta aagattttga
     6601 gaaatttgct caagacaacc aatcatggct tgagctcttt gctgagtata tggctatcaa
     6661 agagcatttt gacaatcttg cttggactga atggccagat gcagatgctc gtgctcgtaa
     6721 agcttcagca cttgaaagct atcgtgagca attggcagac aagttggttt accaccgtgt
     6781 gactcaatac ttcttcttcc aacaatggtt gaaattgaaa gcttacgcta acgacaacca
     6841 cattgaaatc gttggggaca tgccaatcta cgtagcggaa gattcaagtg atatgtgggc
     6901 aaatccacat ctcttcaaaa cagatgtcaa tggtaaggct acttgtatcg caggatgccc
     6961 accagatgag ttttctgtaa ctggtcagct ttggggtaac ccaatctatg actgggaagc
     7021 aatggacaaa gacggctaca aatggtggat tgaacgcttg cgtgaaagct tcaaaatcta
     7081 cgatatcgtt cgtatcgacc acttccgtgg cttcgaatct tattgggaaa tccctgctgg
     7141 ttccgataca gcagcacctg gtgagtgggt gaaaggtcca ggctacaagc tttttgcagc
     7201 cgttaaggaa gaacttggtg agctaaacat catcgcagaa gaccttggct tcatgacaga
     7261 tgaagtgatc gaattgcgtg aacgtactgg cttcccagga atgaagattc ttcaatttgc
     7321 cttcaaccca gaagacgaaa gcattgatag cccacacttg gcacctgcta actcagttat
     7381 gtacacagga acacacgata acaatacggt tcttggttgg taccgtaatg agattgatga
     7441 tgcgactcgt gagtacatgg ctcgttacac gaaccgtaaa gaatacgaaa cagtggtaca
     7501 cgctatgctt cgtacagtat tttcatcagt tagctttatg gcaattgcga ctatgcaaga
     7561 tttactagaa ttggatgagg cagctcgtat gaacttccca tctacccttg gtggaaactg
     7621 gtcttggcgt atgactgaag atcaattgac accagctgtc gaggaaggtt tgcttgactt
     7681 gacaacaatt tatcgccgaa ttaatgaaaa tttggtagat ttaaagaaat aagacaataa
     7741 tcaggagaca actaaacatg ttatcactac aagaatttgt acaaaatcgt tacaataaaa
     7801 ccattgcaga atgtagcaat gaagagcttt accttgctct tcttaactac agcaagcttg
     7861 caagcagcca aaaaccagtc aacactggta agaaaaaagt ttactacatc tcagctgagt
     7921 tcttgattgg taaactcttg tcaaacaact tgattaacct tggtctttac gacgatgtta
     7981 aaaaagaact tgcagctgca ggtaaagact tgatcgaagt tgaagaagtt gaattggaac
     8041 catctcttgg taatggtggt ttgggacgtt tggctgcctg ctttatcgac tcaattgcta
     8101 ctcttggttt gaatggtgac ggtgttggtc ttaactacca ctttggtctt ttccaacaag
     8161 ttcttaaaaa caaccaacaa gaaacaattc caaatgcatg gttgacagag caaaactggt
     8221 tggttcgctc aagccgtagc taccaagtac catttgcaga ctttactttg acatcaactc
     8281 tttacgatat tgatgttact ggttatgaaa cagcgactaa aaaccgcttg cgtttgtttg
     8341 acttggattc agttgattct tctattatta aagatggtat caactttgac aagatagata
     8401 tcgctcgcaa cttgactctc ttcctttacc cagatgatag tgaccgtcaa ggtgaattgc
     8461 tccgtatctt ccaacaatac ttcatggttt caaacggtgc gcaattgatc atcgacgaag
     8521 caatcgaaaa aggaagcaac ttgcatgacc ttgctgacta cgcagttgtc caaatcaacg
     8581 atactcaccc atcaatggtg attcctgaat tgattcgtct tttgactgca cgtggtatcg
     8641 agcttgacga agcaatctca attgttcgta gcatgactgc ctacactaac cacacaatcc
     8701 ttgctgaggc gcttgaaaaa tggcctcttg aattcttgca agaagtggtt cctcacttgg
     8761 taccaatcat cgaagaattg gaccgtcgtg tgaaggcaga gtacaaagat ccagctgttc
     8821 aaatcatcga tgagagcgga cgtgttcaca tggctcacat ggatatccac tacggataca
     8881 gtgttaacgg ggttgcagca ctccatactg aaatcttgaa aaattctgag ttgaaagcct
     8941 tctacgacct ttacccagaa aagttcaaca acaaaacaaa cggtatcact ttccgtcgtt
     9001 ggcttatgca tgctaaccca agattgtctc actacttgga tgagattctt ggagatggtt
     9061 ggcaccatga agcagatgag cttgaaaaac tgttgtctta tgaagacaaa gcagctgtca
     9121 aagaaaaatt ggaaagcatc aaggctcaca acaaacgtaa attggctcgt cacttgaaag
     9181 aacaccaagg tgtggaaatc aatccaaatt ctatctttga tatccaaatc aaacgtcttc
     9241 acgagtacaa acgccaacaa atgaacgctt tgtacgtgat ccacaaatac cttgacatca
     9301 aagctggtaa catccctgct cgtccaatca caatcttctt tggtggtaaa gcagctccag
     9361 cctacacaat cgctcaagac attatccatt taatcctttg catgtcagaa gttattgcta
     9421 acgatccagc agtagctcca cacttgcaag tagttatggt tgaaaactac aacgttactg
     9481 cagcaagttt ccttatccca gcatgtgata tttcagaaca aatctcactt gcttctaaag
     9541 aagcttcagg tactggtaac atgaaattca tgttgaacgg agctttgaca cttggtacta
     9601 tggacggtgc taacgtggaa atcgctgagt tggttggaga agaaaacatc tacatcttcg
     9661 gtgaagattc agaaactgtt atcgaccttt acgcaaaagc agcttacaaa tcaagcgaat
     9721 tctacgctcg tgaagctatc aaaccattgg ttgacttcat cgttagtgat gcagttcttg
     9781 cagctggaaa caaagagcgc ttggaacgtc tttacaatga attgatcaac aaagactggt
     9841 tcatgactct tcttgatttg gaagactaca tcaaagtcaa agagcaaatg cttgctgact
     9901 acgaagaccg tgacgcatgg ttggataaag tcatcgttaa catttctaaa gcaggattct
     9961 tctcatctga ccgtacaatc gctcagtata atgaagacat ctggcacttg aactaatact
    10021 cttcgaaaat ctcttcaaac cacgtcagct ttatctgcaa cctcaaagcg gtgctttgag
    10081 caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa gatacaaatt
    10141 tatactaata catcttgtaa aaaagcgagt ttcgattgaa attcgctttt ttaaatgctg
    10201 tggatttggg tcaatcttgt ctaaaaatag ggaaatccta gatacagtga aggctttaaa
    10261 tgctggtttt tgctgtcttc agccttatat tttttcgtag ttggttacct catatctctt
    10321 gtattcgctt acataaagta ttataatata attgtaggaa agaaggtgtt tttatgatat
    10381 acacacttaa attggtgttg tttattacct ttcttgtaat aagcttgtta cctgataaga
    10441 tttttggaaa aaataaaaaa atttggaaaa tagtttttgc aatattgacg gcagtggcag
    10501 cattgtcatt tatgtactaa gttattttaa gaatgtaggg aaataaaccc tacattcttt
    10561 ttagtttttt ctgttttcta aattctattt atccaagcgc ttcaacattt cttgcttctt
    10621 cgcttcaagt tctgcacgct tttcttcgat ttcggcatgt tttttctcga gttcagaaca
    10681 acttgcacca ttgctaaatt cttttcgcca tcaggagata gggtgagtcg acatgtctat
    10741 tactcaccca aagcagtcct acaaagcagg aattttctgt tacttttttg gaaatagtaa
    10801 cgtttataca gctttgacac ttcgtatcaa agcgccaaac acactccgag ggatttacag
    10861 aaagcagaaa aggaatgatc tggtataaga tcattccttt tctctctttt tctttaagta
    10921 attatataca atgtacgacg aagtcgtcat tgcaatgctg atccaccacc taaagggaac
    10981 tttaaacaac attgataaga taaagaatat aaacaacgaa aatacgttat acccaattaa
    11041 ttttattgta tatctcatga ttaaaagtta atccttccgt tgttaggaat ggcatcattt
    11101 ttatcccata attgtgctaa ataagtcccc ggtgataata aattcatagc ggattctaaa
    11161 gcaacatcat ttacaaacca attacctaga tatctagaaa ttgctgaacg aatagcactt
    11221 tttgctgcat gttttccttt tactttaatt agatttgcaa ggcctgcagt agttcctcct
    11281 aatgctaaag ctattgcagt atctaataga gcacccattt gattaactgt aataccttgc
    11341 caagctgctc taaatggaga gtatgtaggt gggattgtat aatcgccttg taattgtcgg
    11401 ttaattactt ctttgatcca ttgttgtgag acgtctggat gaaaagattg gatttcgttt
    11461 gcaagtgtat tgatttgttc ttctgttaga gaagtgacag gttgaagttc catatttgtt
    11521 tcaatttgtg atacttgttc agaagcgtat acagctgaaa cacttggaat cgctgataca
    11581 attaacacaa ttgacgtcaa aaaaaccgaa ataaatttca ttaatttgtt catgagcttt
    11641 tctccttttt atttgtatct gcttacattt tattatatac tgttattata gtcaataaaa
    11701 atatgctatt atgttaaaaa aatattttta aaaatataaa tggacggatt tattttggat
    11761 tttatttgtt attttgacct gcctctatat tggtaaccat gatttgttta ctttcaatca
    11821 tcaagaattc tcttttcgtg gtagcgtttg gggtctggta ctggccttat atcacttatt
    11881 gttcattgat aagtttgtaa tttcgaatcg aaaataaaga ttagaactat gattgactgg
    11941 ctacttttaa tattgatttt ggaggaagat tttgtctcta ttatttatta ttttaaattt
    12001 atttattttg tataagatct attctttgag gcgggaaaaa tcgaaatact tgatttatac
    12061 ggcctatatc atatttgggg taaatgtagt atatggtatt caatggttat taagagaact
    12121 gatttcaact atttcccctt aatgtgtatg gaaactataa caaaacgcat aagattaagg
    12181 tttgtgtacc tgttcttatg cgtttttata atattgaaga ttttcggtaa gttttatacc
    12241 tttgggaagt ctagtttaga atgctttccc aaccaaaatc tctgcttcga tggtaatctc
    12301 tgtcagttgg ctccagtcaa tcttgctctg gtcaacgtga aagaggagag gagtcatact
    12361 gagtagggct tggagttgtt ctgctgtgat agtcttagtc agagaggcag tttgactaga
    12421 taggatggta aagtgttcct ggaaatgctc cttgatatct tggttagaat actccttgtt
    12481 tgtcagctgg tcctgtactc tttgacggat ttctttgagg tgattttcag ttgggataac
    12541 ctttatcaag ataccgtctt tggataaaac gcgacgaaat tctccatagt tggcaggtga
    12601 gaagatatca agcagaatat ccatgttagc gtcttttata ggaagtcgtg ccaagtcgcc
    12661 aacaaaccaa ttgactgccc agttgggttc acttttagca gcgatttgga ctgaatcttt
    12721 ggagatgtca aaggcataga aagttttttc agagtgactt tcttgtagtt tgcgagaata
    12781 gaatccttca ccacaaccga tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa
    12841 gtcagataca gcatctaaga tagcttggta aaagccggct tctaggattt gttgacggtt
    12901 ttgaaaattt tccttgttat agttagcaga ttgcttgatt tgaggtgcta gattgacata
    12961 gccaaatttc gccaagtcaa aagaatgacg gttgcagcac ttgaaattag tctctaacag
    13021 agtcagattt tcttgacaga taggacaggc aaaggcagtc gcagaagcaa aacgctgaag
    13081 tttgggcttg agatttgtat tcatagttta agtgtatcaa aagaggcaaa tgaaagcaac
    13141 tttaggaata agtagatggg agattcagta gaaataaaac taattctcca atttatagaa
    13201 tgaaattgct tttatatcta aattgctata taataatgat aaggaggaaa taagtatgtt
    13261 aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct tcattatttt tgggtggtgt
    13321 cgcatttggt acccttggtt tgaaaatctt agcaagtaag gaagctaaaa aaggttattc
    13381 taaagctttg gctaaggctt acaagttgaa agacgagcta gatgcatctg tttctgttgt
    13441 gaagcaacat ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc aagagaaaaa
    13501 agaagagcaa ttagatagcc ttataggtga ataatatgtc ttttaaagtg ctacatagag
    13561 gataccaaca tatccgacta tcatcttctt tttcacttac cttggatatt caagactatc
    13621 ttcgttcctt ggcgagagat gaaaagggga ttgagtctat ccagttttac atggatcaac
    13681 agcactttac tctacgcata aaagaaggct tttctgtatt agataatgca gaagcctttt
    13741 taaaaagaat tgataaaggg aaagtttctg agttgatgac tcttcccatt cgtagagaag
    13801 agagtgctta ttctattgtt tcaggtgcag cggttaagcg tgtacttttt cgtagttttg
    13861 tgccgtatcc tattcgctat atatggactt gttatcaggc tttgggttat attagagaag
    13921 cctatcaaac actagcgcgt aaggaactaa cgatggaagt cttggactgt tcggctattt
    13981 tattgtcttt gtttatgaac caatccaaga cagctagcaa tatcatgttt atgcttgatt
    14041 tggggaatca tttagatcag tggtccttga aaaaaactgc aacagattta gaacagagtc
    14101 ttcttgcaaa agagagcgat gtattcctag tacagggcga tacggttgtt agtatcaaga
    14161 gttccgatgt tcaaatagga gatgtcttga tcttatctca aggaaatgaa attctgtttg
    14221 atggacaagt agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca ggagagagtt
    14281 ttccagttga aaaaagagag tctgatttgg tttgtgcaaa tacagtatta gaaactggag
    14341 agttacgcat ttgtgtaaca gataatcaga tgaacagccg tcttttacag ctgattgagt
    14401 tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc aagatggcgg
    14461 ataaagtcgt caaatataat ttcttggggg ctgggctgac ttacctattg acaggttctt
    14521 tttctaaggc tatttctttc ctattggtcg atttctcctg cgctttgaaa atctctactc
    14581 ctgtagctta tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg attaaggatg
    14641 gagatgttct ggagaaatat ctggaagttg atactttctt gtttgataag acaggaacaa
    14701 tcacaactag ttatcctata gttgaaaagg tgttaccttt tggagactat agtgaggaag
    14761 atattctcag aatcagtgcc tgtcttgagg aacacattta tcatcctatt gctaatgcca
    14821 tcgtcaagca agctgagata gagggaattg aacatgagga aatgcatggg aaactccaat
    14881 atatcgcaag caaggggatc aaatctcata tagatggcca accagttctt attgggaatt
    14941 atgtcttgat gcaggatgag cagattcata tcagttcaga acaaaatgct ttaattgaag
    15001 agtacaagag tcactacaat ctcttattct tggcttatca aaatgaattg attggaatgt
    15061 tctgcattca tactcctttg agaaaagaag caaaaacagc cttggataaa cttaaggcac
    15121 aggggaaaaa attgattctg gcaacaggag acaccttgac taggacagag gaattagtca
    15181 aagatttgcc ctttgatcag gtctatacag acttgaaacc tgatgggaaa tttgagttag
    15241 tagagaaact gcagaaagca ggtcacacta ttttgatggt tggagatgga ttgaatgact
    15301 cagcggcttt aactctatca gatatcggtg tggtgatgaa tgagagtgca gatatttcta
    15361 agcagatgag tgatatctta ttgttagata atcgtttgga tttcttccaa gagttggatt
    15421 cgttatcatc atctttgcaa acactcatca agaaaaatat tcaagatacc gttgtcgtaa
    15481 atagtagttt gattggcttc ggcttattta attggctcag tccttcaaat ctctctatct
    15541 tacataatct aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa aatagataga
    15601 tgagagttat taacagcaaa aaggagttac ctttctcgag gctaactcct ttgtttatag
    15661 ataaatgttg aatagtttag taagtcaata caaagtattt tttcttccca cgacggataa
    15721 cagtcagttc attctctaac ttatcagcgt cactcaagac atagtcaagc tcttggatgc
    15781 ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc acgggcttgg cgttttgagt
    15841 taactatacc agatgagacg agcagttcca cgatattgtt gttttcgtct gcctgtactt
    15901 ggtagtttgg cacaccacga agtccttgtt tgagctcttt gacagaaagg tttttgatgt
    15961 ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt gtaggcttct tctccgtgaa
    16021 caagtgtaac aacttcacga gccaagactt tttgagccaa gcgttcgtgt ggcgctgctt
    16081 caaattgttt acgaatatct tcaatctcat caagtgacaa gaaagtaaag attttcaaga
    16141 agcgaacagc gtcagcgtcc atcacgttca tccagaattg gtacatttcg tatggagaag
    16201 tcttttcggg attgagccag acggcatttc cttctgattt accaaatttc ttaccagttg
    16261 catctgtgat tagtggaaca gtgataacgt gaccagtctt gtccgcttta cgacgaagca
    16321 attcggtacc agctgtcata tttccccact ggtcagaacc accgatttga agagtgacat
    16381 tatggtcttg gttaaggacg aagaagtcgt acccttgcat gatttggtaa gcgaactcag
    16441 tgtaagaaat tcctgtttcg attcgttttt ttacagattc cttactcatc atgtagttga
    16501 ccgtgaagta ttttccaata tcacggagga agtcaatgaa gctgatgctg ccaaaccagt
    16561 cgtagttgtt gaccatgaca gccttgtttt cgccattttc aaagtcaaga aaacgagaaa
    16621 gttgtccttg gatagacttg acccagccat ctactgtgtc ttttgtttgg agactacgtt
    16681 cagcatcttt gaaggacgga tctccgatga gacctgtagc accgccaacg agcgcataag
    16741 gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg tggcctaggt
    16801 gaaggctgtc agcagttgga tcgtagccag tataataaga aacttgacct tcttctaggg
    16861 ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa accacgatct tttagctcat
    16921 caaaaatgtg catgtgtctt ttctcctttt taaaattatt gtttctacct attgtatcac
    16981 aaacttgggc aatagcctag cagaataggg aagaaagtgg ctattttatt gaaaatttcc
    17041 cttttgtggt ataatagata gagtgaggaa atccatgcaa aatcaattaa atgaattaaa
    17101 acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag ctagacctgg
    17161 caagaaaggt tcaagtacca aaaaatctaa aaccttagat aagtcagcca ttttcccagc
    17221 tattttactg agtataaaag ccttatttaa cttactcttt gtactcggtt ttctaggagg
    17281 aatgttggga gctgggattg ctttggggta cggagtggcc ttatttgaca aggttcgggt
    17341 gcctcagaca gaagaattgg tgaatcaggt caaggacatc tcttctattt cagagattac
    17401 ctattcggac gggacggtga ttgcttccat agagagtgat ttgttgcgca cttctatctc
    17461 atctgagcaa atttcggaaa atctgaagaa ggctatcatt gcgacagaag atgaacactt
    17521 taaagaacat aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg ggaaatttgt
    17581 aggtttgggt tcctctagtg ggggttcaac cttgacccag caactaatta aacagcaggt
    17641 ggttggggat gcgccgacct tggctcgtaa ggcggcagag attgtggatg ctcttgcctt
    17701 ggaacgcgcc atgaataaag atgagatttt aacgacctat ctcaatgtgg ctccctttgg
    17761 ccgaaataat aagggacaga atattgcagg ggctcggcaa gcagctgagg gaattttcgg
    17821 tgtagatgcc agtcagttga ctgttcctca agcagcattt ttagcaggac ttccacagag
    17881 tcccattact tactctcctt atgaaaatac tggggagttg aagagtgatg aagacctaga
    17941 aattggctta agacgggcta aggcagttct ttacagtatg tatcgtacag gtgcattaag
    18001 caaagacgag tattctcagt acaaggatta tgaccttaaa caggactttt taccatcggg
    18061 cacggttaca ggaatttcac gagactattt atactttaca actttggcag aagctcaaga
    18121 acgtatgtat gactatctag ctcagagaga caatgtctcc gctaaggagt tgaaaaatga
    18181 ggcaactcag aagttttatc gagatttggc agccaaggaa attgaaaatg gtggttataa
    18241 gattactact accatagatc agaaaattca ttctgccatg caaagtgcgg ttgctgatta
    18301 tggctatctt ttagacgatg gaacaggtcg tgtagaagta gggaatgtct tgatggacaa
    18361 ccaaacaggt gctattctag gctttgtagg tggtcgtaat tatcaagaaa atcaaaataa
    18421 tcatgccttt gataccaaac gttcgccagc ttctactacc aagcccttgc tggcctacgg
    18481 tattgctatt gaccagggct tgatgggaag tgaaacgatt ctatctaact atccaacaaa
    18541 ctttgctaat ggcaatccga ttatgtatgc taatagcaag ggaacaggaa tgatgacctt
    18601 gggagaagct ctgaactatt catggaatat ccctgcttac tggacctatc gtatgctccg
    18661 tgaaaagggt gttgatgtca agggttatat ggaaaagatg ggttacgaga ttcctgagta
    18721 cggtattgag agcttgccaa tgggtggtgg tattgaagtc acagttgccc agcataccaa
    18781 tggctatcag accttagcta ataatggagt ttatcatcag aagcatgtga tttcaaagat
    18841 tgaagcagca gatggtagag tggtgtatga gtatcaggat aaaccggttc aagtctattc
    18901 aaaagctact gcgacgatta tgcagggatt gctacgagaa gttctatcct ctcgtgtgac
    18961 aacaaccttc aagtctaacc tgacttcttt aaatcctact ctggctaatg cagattggat
    19021 tgggaagact ggtacaacca accaagacga aaatatgtgg ctcatgcttt cgacacctag
    19081 attaacccta ggtggctgga ttgggcatga tgataatcat tcattgtcac gtagagcagg
    19141 ttattctaat aactctaatt acatggctca tctagtaaat gcgattcagc aagcttcccc
    19201 aagcatttgg gggaacgagc gctttgcttt agatcctagt gtagtgaaat cggaagtctt
    19261 gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagaag tagaggtcac
    19321 aggttcgact gttaccagct attgggctaa taagtcagga gcgccagcga caagttatcg
    19381 ctttgctatt ggcggaagtg atgcggatta tcagaatgct tggtctagta ttgtggggag
    19441 tctaccaact ccatccagct ccagcagttc aagtagtagt tctagcgata gcagtaactc
    19501 aagtactaca cgaccttctt cttcaagggc gagacgataa ttctctaaat gaagtggcca
    19561 atcaatggat tgccactttt ttcttttcgt gttacaataa gggtatgaat cagtatcaga
    19621 aaaagattgt taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg
    19681 gaattttagg agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta
    19741 tgcgtttgac actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc
    19801 aagtgctaga tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt
    19861 tggggatttt ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga
    19921 cagcaactat tttacagttt attagccctg tctttatcct cttttacaat cgcttggttt
    19981 atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt
    20041 gcttgatggc gacaaaggga gatctctctc agttatccat gacgccgcta gctcttataa
    20101 caggtttgct gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta
    20161 agcgttatgg ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca
    20221 atgtcctctc gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt
    20281 gcctcattat cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt
    20341 ccttggtttc tcctttggtg gttgccgtta tcagtgccag tgaacctctc tcttctgctc
    20401 tcttgagtgt tttgttctta ggattagtag tggattggtc cctccttcta gctatagcct
    20461 tgattatttt acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag
    20521 tcttttctta attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag
    20581 ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt
    20641 atctcacatc cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc
    20701 ttttttggta gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa
    20761 atgaacgctc aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa
    20821 gtaacctttg aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat
    20881 gtcctattcg gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa
    20941 gattatgttg tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct
    21001 atcaacgctc gtatcgagcc aggtgctatt atccgtgacc aggtggaaat tggtgacaat
    21061 gctgttatca tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg
    21121 attgacatgg gtgccatcct tggtggccgt gccatcgttg gaaaaaatag ccacgttggt
    21181 gcaggtgcag ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga
    21241 gacaatgttc ttatcggtgc taatgcagtg gttatcgaag gagtccaaat cggtagtggt
    21301 tcagttgtcg cagcaggagc tattgttacc caagatgtcc cagaaaacgt ggtagtagca
    21361 ggtgttccag ctcgtattat caaagaaatt gatgctcaaa ctcaacaaaa aacagcgcta
    21421 gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca
    21481 gcctctttct gctatatcgg aggacagata gatgttagat ttgattcaga ctagacgaga
    21541 tttacaccag attccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga
    21601 tgtgattgag aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg
    21661 gattttggtc tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat
    21721 tgatggcctg cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg
    21781 catgcatgcc tgtggtcatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc
    21841 ccttgaggag caacccaaga ataatctgct ctttctattt cagcctgctg aagaaaatga
    21901 agctggtggt atgctcatgt atgaggacga tgcttttgga gattggttgc cagatcaatt
    21961 ctatggtctc catgttcgtc cagatttgaa agtcggccag attgcgacta atactcatac
    22021 actctttgca ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc
    22081 ttttcctcat gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca
    22141 gtcagttgtt agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt
    22201 tcaagctgga accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg
    22261 tgccttgaca caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg
    22321 ggttgcagct gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc
    22381 tgttgagaac aatccagcct tggcgcgtga actgatggac ttctttgacg agaaagacgg
    22441 aatcgagttg attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc
    22501 aaaggttgat ggcgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc
    22561 tcaaatgagt cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct
    22621 gaaaaagaag gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc
    22681 ttgcatgaaa tgaaggcttt atctcaagaa caaaaacagg ctatagacca agctttaacc
    22741 gagcggattt tacaccatcc cgtctaccaa gaagccaagg tcatcgcaac ctacctctct
    22801 tttcctcatg agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagaag
    22861 gttttaatac ccaaaactta tcccaagggg cgcatggact ttgtagtcta tgatccgcag
    22921 cagttggtaa aaactgcctt tgccttactg gagccacagg gagatttgga agtggtggat
    22981 gtatctcaga ttgatttgat tcatgttcct ggcctggctt ttacgacgga tggatatcgg
    23041 attggatatg gtggaggtta ttatgaccgc tatctggaac atttttctgg tcatactttg
    23101 agtacggttc atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt
    23161 caggaggtat taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt
    23221 cctcttagtg acggccttgg tatttttact aatgttggtc actgcaggcg gaaactttga
    23281 cagggcagat acattatttc gatttggagc catgtatggg ccagctattc gcctctttcc
    23341 cgagcaggtt tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat
    23401 tgttaatatg ctttcacttt attatcttgg aaggcaggta gaggagattt tcggctctaa
    23461 gcagttcttt tttctctatc tcttatcagg aatgatgggc aatctctttg tttttgtatt
    23521 tagtcctaaa tccttagcag caggcgcctc tacctctctt tatgggctat ttgccgcgat
    23581 tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc aatcctatct
    23641 gacacttttt gtggttaaca ttattggaag tgttctgatt ccaggaatca gcctagcagg
    23701 ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga
    23761 aaaacggatg tataacacca gccagagatt aggagcggta gtcttgttcg taggactcgc
    23821 cattttgctt ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat
    23881 gaaaaaagat aaggcatttt ttgaacctta tctttttatt ttattttatt ccttctcagt
    23941 caattctttt ccaagttgga tgaggtaatt cttcaaatca tctttgactt gtgggtgttt
    24001 gagggcgtag tcgatggatg ttttcatgaa gccaaacttg tctccgacat cgtaacgagc
    24061 cccattgaac tcacgagcaa atacacgttg tgttttattg agggtgtcga ttgcatctgt
    24121 cagctgaatt tcatttcctg cacctggagc ttggttttcg aggatttgga aaatttcagg
    24181 cgtgaggagg tagcgtccga taatagcaag gtcgctagga gcgtcctctg gagctggttt
    24241 ttcaacaaag gtttcaacac tgtaaagacc atcttttcct tcgccttgcg gagcaataac
    24301 cccgtaagca gatacttcgt catgagggac tggcatgaca gcgatagtag acgcgtgggt
    24361 acgctcgtag tcatccatga gttgtttggt aagtggaaca gccttttcgt ctgtgatatc
    24421 catcaagtca tcaccaagca taacgacaaa aggttcattt ccgacgaaag ccttggcttg
    24481 caaaacagca tctccgagac cgcgtggatg agtttggcgg ataaaatgca gccgcatgtc
    24541 agttgtttta tcaactagct tcaaaagatc tgttttccct ttttctttga ggttatattc
    24601 caattcgaag tttgaatcga agtggtcctc aatagaacgt tttgatttac cagtgacaac
    24661 tagaatatct tcaatacctg atttgagagc ctcttccacg ataaactgga tagttggttt
    24721 gtctacgatt ggcaacattt ctttggcaag ggccttggtt gctggtaaaa atcgagttcc
    24781 tagtccagca gcagggataa ctgcctttct aacttttgat gtcataaaaa tcctttctat
    24841 agagggttaa gaccactcat tttctgcttt aaattcattg ttcatgatgt cataaatggc
    24901 atctttgata ttggttccgt gataaataac ttggtaaata gcctgtgtaa tgggcatata
    24961 gactccaagt tcttgggcta gttcataggc tgctcgagtc gttgaaattc cttcgattac
    25021 catgcccata ttagcttcta tatcagctag ggattctcct cgtccgagag catctccagc
    25081 tctccagtta cgagagtgga tggaagttcc cgttacgatc aaatctccca caccagataa
    25141 gccgctatag gtcaatggac tggccccgag tgctacccct aggcgggtga tttctgctaa
    25201 acctcgagcg atgatggctg ccttagcatt atcaccaaat ccaagaccat gtaaagctcc
    25261 agcaccgaca gcaataatat ttttaagagc accagcagtt tcaaccccga taacatccgt
    25321 attggtataa agtcggaagt agtgattact aaatagctcc tgaacgtatt gagctgtttg
    25381 taaatcttta gaagcagcag ttattaaagt taggtcacgc acaatggtct cttctgcatg
    25441 actaggccct gaaacaacga cgatatcact acggagatgt tcaggaattt cttcttcaag
    25501 aatggttgat aatcgtttat ggctatcagg ttctaatccc tttgatgcgt gcatgatgat
    25561 aaccttatgg tccaaggttt gtgcaacttg ctgggcaaca agtcgtgtca cttttgttgg
    25621 gacaacaaac aaaatcgcat ccacatcttt caatgtttct gctaagtcgg tgtaggcaat
    25681 gatattttcg tctagaacga catctttaaa gtagtgctta ttagtatggt gtgtattaat
    25741 ttcattgatt tgctcgggaa gatttcccca aatacgtacc tcgtgtccat tgtcatttaa
    25801 gacttgtgaa agggcggttc cccaagaacc aggccccaag acggcgacgg tttgtttttc
    25861 catgatttcc tccttgatag agttctttct cttattctat catattctag gggattttgc
    25921 acttgcatta ctggggtatg gtggaaaaat acacaaaaac cgagacgaag ggataaactc
    25981 ttagtcttta gttaaagtga gaagaaatct gatagatagt ttgattcagt atatgcttat
    26041 aatagaggta aacaactcag gaggttcttg taggttgcga gagtttggcg aaaaaattaa
    26101 aagattacgt ttggctaaaa aaatcagtcg ttcagaattt tgtggtgatg agtctgaatt
    26161 aagtatccgt caattaatta gaattgaaaa tggagaatcc agaccaacac taacaaagtt
    26221 aaaatatatc gctgaacgtt tgggggttga agattacaag ttgatgccaa gttatataga
    26281 gttggataag gaatacctag aattgaagta tttcttgatg aggactccta catacgaaga
    26341 tgaaactatc gcccaaaaga aagagagtgt ttttgataag atttttgaag agtattatga
    26401 taggctagct gaggaagaaa gatttatcat cccaaattat tcatatctgg cactaacgaa
    26461 ctacacagtt caaaaattac cagaaaagct agttgaaata ctgtccttct ggtgattttg
    26521 cttaatttct gatgttcgag acatgattga ggagatttgt cttgattttt tcctaaaaaa
    26581 gggcagactc ctcccttggt ttgatgctcg atttttaaaa taaggtgact tattctgtta
    26641 ggcatgtttt cccctgccct ctagctctat atggaacagg gagtatcaga tttatctggc
    26701 agattgtatc aaataaggct tgaaactgtt ttgaataggc atatagactt gagaatttga
    26761 gaatatgtcg tctagcagta gagacatatt ttccggcaat atgaaggaag agacgtcgaa
    26821 aacgcttgat agtcaagacc tttacttcat caccagctag ctgctttaaa aagaggtaga
    26881 gattataagc cagacagccc atcatcatac gtacttcatt cttaatcatg gtcgaactat
    26941 ctgtcttatc cccaaagaat cctgctttcc tttctttgat aaagttttca gcattccttt
    27001 gttcacgata gaattgaaac agctcctcac tatctacact gcttaaattg gtcaaatgaa
    27061 cttttttaca accataaaaa agagcactta atcgtactct tctcttttaa ggattaaagg
    27121 attagttgaa ttaattcaaa tccactagtt ctcctgtttc taggtagact aggcgttcac
    27181 aaatgttagc aatgtaatca gcgaagcgtt ccagatgccc tatgatataa aggtattgtg
    27241 ttccattggg aattgaggtt tcttggtctt tcataagtcc aatgatttcc tttgataagg
    27301 cataataata ttggtcaatc tgttcatctt tttgagcaat actaatagct tttgaggctt
    27361 ggtgcaaagg aaaggcaacc aataaatcgg ctagcatgct gagggataat ttacccattt
    27421 ggtgtaactg ttcttcgtca ggggctagtt gattttcttt tagttgcaaa acagctttgg
    27481 caatgcctgc catatggtct cccatacgtt caaggtctga acaagaagac atgatgctaa
    27541 tcacaaatcg aaggtcagac acttgtggct gctgcaaggc caacaaacgg gcacaggtca
    27601 attcgatagc gctttgacct tggttgatag catgatcctt attgataatt agctctgcca
    27661 tctccttgtc tttggaggct aaggccagta aggcttttga agctgtttca aggacaagtt
    27721 gccctagtcc taaaaaggat tgttctaatt catgcaattc taagtcaaat tgatttctca
    27781 taggtttttc cttccttatc cgaaccgtcc tgaaatatag tcttctgtgc gctgatcttt
    27841 tggattggta aacacgtcaa cggtatctcc aaattcgcaa atttctcctg ttaagaaaaa
    27901 agcagtttta tctgaaatac gtgaagcttg ttgcatgtta tgggtaacaa tgataatcgt
    27961 ataatctttt tttagttgct gaatgaggtc ttcaattttt aaagtggaga tagggtctaa
    28021 ggctgaagtc ggctcatcca ttaacagaat atcaggttct actgctaaag ctcgcgcaat
    28081 gcaaaggcgt tgctgctgac cgccagataa ggacatggca ctctttttaa gatcatcttt
    28141 gacttcttcc caaatggctg ccccttttaa agatttctcc actaaggcat ctaattgttt
    28201 tttgtctcga ataccatgtg tccttgggcc ataagccacg ttatcataga tagacatggc
    28261 aaagggatta ggctgttgaa aaaccatccc tacacgctta cgtagctgat taaggttgaa
    28321 tttgctacta taaatatctt gctcatctaa gaggacttgg ccttcaatat ggcaagaagg
    28381 aaccaaatcg ttcatccggt taagggtttt tagaaaagtt gatttgccac aaccagatgg
    28441 gcctatcaag gcagtaatct gtctttctgg taattgaatc gaaatatttt ttaaggcttg
    28501 aaaatccccg taaaataagt ctaggtgtct gactgaaaat gttcccatac taggaagctc
    28561 ctttcacaag tttccgagat aataagcttg atagagtatt tatcattaaa acagtaataa
    28621 ttaaaatcac gccggtagca taggcttcat tgacatgtag cccctcactt gacagcatat
    28681 acatatgtag ggctagagaa cggcctgaag acatgagact acttggcgta ttggtagagg
    28741 tacctaatgt atacatgagg gcagctgttt caccaacgat acggccaata gctagtatca
    28801 ctccagctaa aatacctggc atggcaactg gtagaacaat tctaaaaaca gtccgtaact
    28861 tacctgcccc aagtccataa cttgcttgac gcatgctatc actaacagat aaaagggctt
    28921 cttctgttga gcgaataatg actggcaaca ccatgataac tgaggttaag attcctgata
    28981 acagagagta ttgaaaacct aagaagacta caaagaagag catgccaaac agaccaaaaa
    29041 caatggaagg aatcccagac aaggtatctg aggccaatcg catgatttta acacaaaggg
    29101 aatctttttt tgtatattcc acaagataaa aaccagcaaa aatccctatg ggcaaagcta
    29161 aaagaagagc accaaaaacc agaataacgg tggaaataat cgctggcata agggaaatgt
    29221 tctcagaagt ataagtccaa gaaaagaggg atagacttag atgaggtaag cctttgatga
    29281 ggataaaacc aatgattaaa aagagagagc caaaggttaa agctgaaaaa caataaacga
    29341 gaagttttag caggtattta ctcataagat gattttcctt tcaagtaggc aaagtaggca
    29401 ttaatcaaga gaataaggaa aaagagaact gctgaggttg caataagggc ttccctatgc
    29461 tgacctgatg cgtaagccat ttccagaaca atattggttg ttaaggttct ggttcctgaa
    29521 aagagtccac ttggaataat tggctggttg cctgccacca aaataactgc catggtttca
    29581 cctactgcgc gaccgattcc taaaataact gctgataaaa taccagatct cgcagctggc
    29641 aagatgacac taaaaatact ccgttcatga ctagctccta gagccaagct accagaataa
    29701 tacgttttgg gaactgttcg gatagcagat tctgacaaac tgataatggt tggcaaaatc
    29761 attattccta atagtaacga agcggttagg acactcatgc catttcctaa aaaggttcta
    29821 atccaaggca ccaataattg taggccgaaa aaaccataaa caatagatgg aatggctgcc
    29881 atcaagttga tagctgattt taagaagcca tagacgggct ttggacaata ataaaccata
    29941 aacaccgatg tcaagatgcc tgttggcacc ccaatcacaa tcgctcctaa ggtaattaat
    30001 aaggaaccaa cgatcattgg taaaatacca tagcttgccg gaatgttcgt tggcgaccaa
    30061 tcactgccta ataaaaaacg ggcaaagccg tagttagcca tgaaaggtaa gccattacta
    30121 aaaataaaga aacagattag caaaatagct acaacagcta ctgttgcact catgaaaaaa
    30181 attgccctaa aaactgcttc tttgaaggct tgttttgtca catcttgtcc tttctagtga
    30241 agaaagtaag ggagatacga cacctcccta cttgccttct ttatcttatt gtacgatgaa
    30301 acgtctgcat ctctttagag atttatggag caaacatttt atttaatctt gtcccaggtg
    30361 gttaatttgc cactaaaaac gtctgcaagt tcagccatac tgacttggct tgccttattg
    30421 tcattattga ccacaacagc aataccgtct aaagcaatag catcatgggt gagactctta
    30481 ccttcttcag gagttaattc cctagaaacc ataccaatat cagcggtttt ctccttaaca
    30541 gcggtaatac ctgctgaaga cccattagag gtaatatcaa tcgtaacttc tggattttct
    30601 tttttataag cttctgctaa tttttccatt aaagaagata ctgaagtgga acctacaaca
    30661 gacaacttgc ctgataagtg ttggcttgta tattctgtgg tttcagtttt agcttcaata
    30721 aatttattat ctgtgaccac ttgttgacct tgtttggagt ggataaagct gataaaatct
    30781 tgacctagct tggaaagatt agaagaccaa acaatgttga agggacgttg aagagggtat
    30841 tcaccatcta aaactgtgtc tcgactagcc ttgacaccat caatctctaa agccttgaca
    30901 gatttcgtta aagatcccaa ggagatgtag ccgatagcat tagcattccc ttgaactgct
    30961 gagagaacac cttctgtact attttgaatc acagctgttt tggcagtgtt gtcaattttt
    31021 ttatcaccgt cttttttgag aatccctgtg atttctgtga aggcaccccg tgtcccagag
    31081 ccattttctc gtgaaatcac ctcaatcgtt cctgaagctg actgtttgga agtagatgac
    31141 tgattgccac aggcaacaag cccaaatcct gataagccaa tggctgcaag agtaagtatt
    31201 tttttgaatt tcataataat cacctttatc tctatgtatt tttcttgtgt aggcttacta
    31261 catttatagt ctaacaagtc tttgtaaagg tttatccctg attcatgtaa agattgtgta
    31321 aagaatcaaa aaaagccact tttgaaaaat ggctgctcct aaaaatagct ttaaaaatta
    31381 ttagtcctgt gcgaaagatt ggttaggaag aaaaatcgtg aagcaactgc ctctgccaag
    31441 ctgactcgtc accgtgactt ggccacctaa taattgactg agttctttga caatggcaag
    31501 gccaagacca gtgccaccag tttgtctgct tcgaccttta ttaactcggt aaaaacgttc
    31561 aaaaatacga tcctgctcta attgactaat accaatccct gtatctgata cagaaatctt
    31621 aatgccttcg ttcacctttt gggtcttgac ctcaattttt cccccttgtt cagtgtaacg
    31681 gatggcattg gataaaagat tgagtaagat ttgggaaagt aattgactat ctgatacgag
    31741 ggtgacatca tctggcacct gcacctttag ctgtaaatcc ttcttcttga gctgaggttg
    31801 caagctttga gtcaaatcct gtacaaattc tgccaaagaa agggtcgtcc attgtatagg
    31861 catttgttga gccttagata aggtaagaag atgctcaaca atatgctcaa gacgcaagct
    31921 ttctttgtaa ataatgtcta gaaagtcatc cttgagcgct tcttcttcag ctgacatccc
    31981 cttaatggtt tcagcaaagc ccttaatcga agtaactggt gtcctcaatt catgggaggc
    32041 atttgagaca aaggctaaat ttaacttttc ataagttcta atcgttgtta aatcatatag
    32101 caagacgagc acagcttcca cagattgggt ggggctaaaa acgggaactg ctgtcacttc
    32161 taaaatcaag tcaccctcat gaaacccact tacttcttgt tttaaccttg ttttttgatc
    32221 aaaggcttgg tgaactaaat tccgaatatc catccgtttg aggtcatcaa gtgaacttat
    32281 gtcgccgtcc acatcgggaa aataatgagg cagagagcga ctggataata acatctgacc
    32341 ttgagcggaa actaaaaacg tccccatggt taggtgcgac agaagaacct ccattgtttc
    32401 ggctaggtcc ttgtattgct gatcctgttg ggagactttg gtttttaggc cagacacata
    32461 ctgagccaaa gactttaagt cttcttgccc tttttctaaa aagtattcac tactggtcaa
    32521 gagaggttgg tgcaaggtct caaaagcaac ttcccatttc caaaggcaaa agagccagta
    32581 gccacctagt cccaaagaaa gggctagaag aaagagaccg atgcctttac tgatccaagt
    32641 taatgccatc cctgcaatca gaatgaggct aacacttaga ttgactagcc aaaattgaag
    32701 gtagcgtttc atctataact ccttgaactt ataaccataa ccccgaatgg ttcgaataaa
    32761 ttgaggggct ttaggattgt cttcaatttt ttccctcaac ttaccaatat gaacgtccac
    32821 caaacgtgtt tcctgcccaa agtcataccc ccagatacgt tccaaaagac gctctctagt
    32881 cagtgtcatg ttgggatgtt tcataagata gagcaagagt tcaaattctt ttggggtcaa
    32941 actcagtaac ttattcgcct tgtagacttc atgacgctca gggtatactt tcaaggtccc
    33001 aaatagccaa gaattgtcag cgatattatc tgaatcatct ccttcttgtt ttcctttagt
    33061 tcgcctgagg acagccttga cacgcgccag taattctcta gggctaaaag gcttggtcag
    33121 gtagtcatca gcccctaatt ccaaggccaa aaccttatca aattcatcac ttttcgcaga
    33181 aaccatcata attggagttt tgacgccttt ggctctcagc cgcttacaaa cttctatgcc
    33241 atctaattgt ggtaacatga tatcaagcaa gataaaatca aagggttctg tttctgccaa
    33301 agctaaggcc ttccgtccat ttgttaccaa ttgagtagaa aagccttcct tacttaaatg
    33361 gtagtcaagc aatttcagaa tgtgttcttc atcatccact aataagactt gttttgtcat
    33421 ctattatctc ctattggtaa cattataaca caattatcag aaatcctaac attgctaaat
    33481 cagattaaat ttgcttataa agactagtat ctggtcaaac gctcaatcat ctccttgtgc
    33541 tctggatagg tcgccagtag atctaccctt tcaaataatt caaaatcctc aaattcaaaa
    33601 ccaggagcaa caagacaaga aaccagagca tcatccttat caactgttga tccccaaata
    33661 gtgcccttag gaacacagta gtgaagttgt tgccctttgg atatgtccag gcctaaagtg
    33721 actgcttcgt agtgaccatc tgctgtaatc atgtgaacag taagtgggga ttctgcatga
    33781 aaataccaga tttcatctgc tgtcaatcgg tgaaaatgtg aaggattcgt ttcttctaat
    33841 aagaaataaa tactggtata aagcgccctt cccttaccag caaggtttat agtgtctgaa
    33901 gctttttttg tttgtctaaa atagccacct tcaacatggg gagctaactc tagagttctt
    33961 atcaagtctt ctttatccgt cggagccaat gggttgaagt aactcttgtt caaagtggtt
    34021 ttacgatttc aagaactcct ctcagttctg aggacacggt aatgattgat gcgacggaag
    34081 tacaaatcaa tcgccctaaa agaagaatta gcgaatgatt ctggt
//
LOCUS       DAVBNN010000018        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBNN010000018 DAVBNN010000000
VERSION     DAVBNN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.018"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ847_000932"
     CDS             complement(21..833)
                     /locus_tag="VQ847_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3050285.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ847_000933"
     CDS             1023..2441
                     /locus_tag="VQ847_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3050286.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ847_000934"
     CDS             2494..3201
                     /locus_tag="VQ847_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3050287.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ847_000935"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ847_000935"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3050288.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ847_000936"
     CDS             4279..5601
                     /locus_tag="VQ847_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3050289.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ847_000937"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ847_000937"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3050290.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ847_000938"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ847_000938"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3050291.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ847_000939"
     CDS             complement(7036..7353)
                     /locus_tag="VQ847_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3050292.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ847_000940"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ847_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3050293.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ847_000941"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ847_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3050294.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ847_000942"
     CDS             complement(8829..9251)
                     /locus_tag="VQ847_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3050295.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ847_000943"
     CDS             9398..9574
                     /locus_tag="VQ847_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050296.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ847_000944"
     CDS             9976..12189
                     /locus_tag="VQ847_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3050297.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ847_000945"
     CDS             complement(12411..12887)
                     /locus_tag="VQ847_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3050298.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ847_000946"
     CDS             13110..16313
                     /locus_tag="VQ847_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3050299.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ847_000947"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ847_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ847_000948"
     CDS             complement(17456..18085)
                     /locus_tag="VQ847_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3050300.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ847_000949"
     CDS             complement(18095..19096)
                     /locus_tag="VQ847_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3050301.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ847_000950"
     CDS             complement(19127..19768)
                     /locus_tag="VQ847_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3050302.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ847_000951"
     CDS             complement(19787..20602)
                     /locus_tag="VQ847_000951"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3050303.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ847_000952"
     CDS             20873..21307
                     /locus_tag="VQ847_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3050304.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ847_000953"
     CDS             21319..22509
                     /locus_tag="VQ847_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3050305.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ847_000954"
     CDS             22520..23011
                     /locus_tag="VQ847_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3050306.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ847_000955"
     CDS             23026..23805
                     /locus_tag="VQ847_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3050307.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ847_000956"
     CDS             23792..24610
                     /locus_tag="VQ847_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3050308.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ847_000957"
     CDS             24610..24903
                     /locus_tag="VQ847_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3050309.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ847_000958"
     CDS             24925..26826
                     /locus_tag="VQ847_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3050310.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ847_000959"
     CDS             26886..27887
                     /locus_tag="VQ847_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3050311.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ847_000960"
     CDS             complement(27997..28332)
                     /locus_tag="VQ847_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050312.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ847_000961"
     CDS             complement(28343..28585)
                     /locus_tag="VQ847_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050313.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ847_000962"
     CDS             complement(28596..29138)
                     /locus_tag="VQ847_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3050314.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ847_000963"
     CDS             complement(29154..29348)
                     /locus_tag="VQ847_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3050315.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ847_000964"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ847_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3050316.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ847_000965"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ847_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3050317.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ847_000966"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ847_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3050318.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ847_000967"
     CDS             33051..34031
                     /locus_tag="VQ847_000967"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3050319.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10306 a         6071 c         7607 g        10140 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgaggcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttctt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBNN010000019        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBNN010000019 DAVBNN010000000
VERSION     DAVBNN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.019"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ847_000968"
     CDS             289..2790
                     /locus_tag="VQ847_000968"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3050320.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GVGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ847_000969"
     CDS             2984..3679
                     /locus_tag="VQ847_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050321.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ847_000970"
     CDS             3691..4107
                     /locus_tag="VQ847_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050322.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ847_000971"
     CDS             complement(4922..5014)
                     /locus_tag="VQ847_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3050323.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ847_000972"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ847_000972"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3050324.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ847_000973"
     CDS             6127..6699
                     /locus_tag="VQ847_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3050325.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ847_000974"
     CDS             6930..7688
                     /locus_tag="VQ847_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3050326.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ847_000975"
     CDS             7697..8500
                     /locus_tag="VQ847_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3050327.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ847_000976"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ847_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3050328.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ847_000977"
     CDS             9794..11647
                     /locus_tag="VQ847_000977"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3050329.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ847_000978"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ847_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3050330.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ847_000979"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ847_000979"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3050331.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(15264..15341)
                     /locus_tag="VQ847_000980"
                     /pseudo
     CDS             complement(15264..15341)
                     /locus_tag="VQ847_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            15398..16447
                     /locus_tag="VQ847_000981"
     CDS             15398..16447
                     /locus_tag="VQ847_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3050332.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ847_000982"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ847_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3050333.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ847_000983"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ847_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3050334.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ847_000984"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ847_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3050335.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ847_000985"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ847_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3050336.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ847_000986"
     CDS             24247..28638
                     /locus_tag="VQ847_000986"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3050337.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ847_000987"
     CDS             28740..29003
                     /locus_tag="VQ847_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3050338.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ847_000988"
     CDS             28996..29274
                     /locus_tag="VQ847_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3050339.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ847_000989"
     CDS             29295..29447
                     /locus_tag="VQ847_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050340.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ847_000990"
     CDS             29469..30710
                     /locus_tag="VQ847_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3050341.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ847_000991"
     CDS             30720..30950
                     /locus_tag="VQ847_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3050342.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8791 a         5922 c         7249 g         9000 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt tctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagttggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg agcgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcca
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttgg tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBNN010000020        30091 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBNN010000020 DAVBNN010000000
VERSION     DAVBNN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.020"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ847_000992"
     CDS             59..772
                     /locus_tag="VQ847_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3050343.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ847_000993"
     CDS             786..1433
                     /locus_tag="VQ847_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050344.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ847_000994"
     CDS             1571..2224
                     /locus_tag="VQ847_000994"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3050345.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ847_000995"
     CDS             2234..2698
                     /locus_tag="VQ847_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3050346.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ847_000996"
     CDS             2711..3979
                     /locus_tag="VQ847_000996"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3050347.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ847_000997"
     CDS             3993..4253
                     /locus_tag="VQ847_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050348.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ847_000998"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ847_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3050349.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ847_000999"
     CDS             5779..6747
                     /locus_tag="VQ847_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3050350.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ847_001000"
     CDS             6763..7755
                     /locus_tag="VQ847_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3050351.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ847_001001"
     CDS             7973..9016
                     /locus_tag="VQ847_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3050352.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQSNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ847_001002"
     CDS             9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ847_001002"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3050353.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10829..11818
                     /locus_tag="VQ847_001003"
     CDS             10829..11818
                     /locus_tag="VQ847_001003"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3050354.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ847_001004"
     CDS             complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ847_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3050355.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13455..15005)
                     /locus_tag="VQ847_001005"
     CDS             complement(13455..15005)
                     /locus_tag="VQ847_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3050356.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15021..15800)
                     /locus_tag="VQ847_001006"
     CDS             complement(15021..15800)
                     /locus_tag="VQ847_001006"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3050357.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ847_001007"
     CDS             complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ847_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3050358.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16910..22123)
                     /locus_tag="VQ847_001008"
     CDS             complement(16910..22123)
                     /locus_tag="VQ847_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3050359.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(22167..28646)
                     /locus_tag="VQ847_001009"
     CDS             complement(22167..28646)
                     /locus_tag="VQ847_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3050360.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDNETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     DPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(28855..30033)
                     /locus_tag="VQ847_001010"
     CDS             complement(28855..30033)
                     /locus_tag="VQ847_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050361.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         8712 a         5833 c         5599 g         9947 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acggggtttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaatccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga
     9061 catggcctta gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt
     9121 ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat
     9181 gactgataaa gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct
     9241 caaaggagat ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag
     9301 ggaaaacatc ccaacagctg gagcagcatc gccagaagct agctctgtac ctgtagcaag
     9361 tacctcaaac gatgatgata agagcgatga tgcttttgat atcgttgtga ttggtggagg
     9421 tcctgctggt tatgttgcag ccattaaagc tgcccaattc ggcggtaagg ttgcccttgt
     9481 tgagaaatct gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta
     9541 ccttcataac gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat
     9601 tgaaaatcct aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt
     9661 taatactctt gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa
     9721 aggaattggt acaatcacta aagacaagaa cgtcttggta aatggctctg aattgcttga
     9781 aaccaagaaa atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat
     9841 ggaatctcca cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag
     9901 ccttgttatc atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt
     9961 tggttcaaaa gtgactgtta tcgaaatgat ggactgtata gttccagcta tggatgcgga
    10021 agtttctaag aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac
    10081 taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga
    10141 cgatatcatc gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat
    10201 tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac
    10261 ttcagttcca ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc
    10321 agctttccgc atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcaattgc
    10381 caaattgaat ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt
    10441 gacagaagaa caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc
    10501 taacggtcgt gctattgcat ctgacgctgc tcaaggtttc gtaaaagtta tcgttgataa
    10561 gaaatacgga gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa
    10621 cgaagcatca agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca
    10681 cgggcaccca acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc
    10741 catccattca cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag
    10801 tttctatcat ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac
    10861 tgcttttaat attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat
    10921 cttcctactt tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga
    10981 agaaatcaac cgtgattatg ttcgtgaaaa tggtattgag gtagttcgcc gtattagtgg
    11041 tggtggagct gtttaccacg atttaaataa cctcaactac acgatcatct ccaaagaaga
    11101 tgaaaataag gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca
    11161 acttggggtt aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt
    11221 ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt
    11281 tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc
    11341 aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa
    11401 aatcacagtc gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga
    11461 gatgactgaa tacgtctttt cagaagaaga attggccgaa atcaatcgca tcaaggatac
    11521 taagtttgga acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg
    11581 aaccaaattc actagtggta aggttgaagt ctttgctaac gttactgaat caaaaatcca
    11641 agacatcaag atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt
    11701 ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat
    11761 cacacgctac ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat
    11821 caaaaagaag ttggccaact aaccaacttc tttttttgat atttatttac ataatttaaa
    11881 atacgtaaaa ttataaacta tctagagcat tcttttgttc atcattaaca atatgggtat
    11941 agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg actgactaaa acttgtgatt
    12001 tagtcgcatc atagagccta gttgctagcg tatggcgcag tttatggggt gttacacgca
    12061 ctttaaaatc ctctgagtat ttagcaacca ttttctcaac gctagaagca tcgatacgat
    12121 taggaacacc tctgtagaga gttaaaaaaa gggctgtatc tgttttttcc gttttatagc
    12181 gttgattccg aatggccaga taattctcta aataaggttt agcaaaagca gcgacattga
    12241 ctgagtcacg tttgccacct tttcgagtaa catcaataac catcattttt agattgagat
    12301 ctcttagatc tagattaaca gcttcagata agcgaacacc agatgccaag agaagggcaa
    12361 taatggctaa atctcgttct ttatttttgt tgaatgatga gagagctcga tttgaaagct
    12421 gttgtgggtg ctcttgatcg atataagtta gaaaacctgc tgtttcatca cctagaaaga
    12481 gtttttgctt gatattttca gctctggcag caagggtttc tttctttttc ttggttgaaa
    12541 cttttttcat tacattacga tagaaataag gttccccctg atcattttca acctcctcgg
    12601 ttagatactt gtaaagacta gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa
    12661 caccttgttt tgttgtatta gcattcagca agggacgttc acgtagataa aggataaagg
    12721 attccatgtc tttcttagac atattttcca aaactgataa aggaatatcg gatattttat
    12781 cagcgtttga aataccagac tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt
    12841 attcgtacag ggttgtaaaa ctgtagggca cagccagttt agattggtag tattccagaa
    12901 cataccaggg catgagttgt tttagtttgt cgattcgttc cagtaaaatc tcacgtttca
    12961 tgtattttct ccataattaa gtatactagt agtatagcat agacttgtat atttttcaag
    13021 aaaattatag tttttcagaa agatgttata ggagtttttc aaagtgataa aaagacttag
    13081 acctacaaac aaaacagaat aaggaaaata ataaaaatct cacccactaa acttctgtta
    13141 atactacata gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca
    13201 tttcactata taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt
    13261 gatacagtaa actcctttct agctttatgc tttatcattt ctaacttaat tatagtctta
    13321 tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc
    13381 tcatttctga gaatcggttt tctaaataaa tcaaaccgat catttacata acataaatta
    13441 tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact ttttggaata
    13501 accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg
    13561 ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt
    13621 ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat
    13681 acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa
    13741 tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct
    13801 cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa
    13861 tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga
    13921 ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg
    13981 aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa
    14041 aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga
    14101 tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc
    14161 aagatgggat aatatgccct atccaaatgg attttttgac caatcaagtc ataaactctt
    14221 ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg
    14281 acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg catatccaat
    14341 actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga
    14401 gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt
    14461 gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag
    14521 gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct
    14581 ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata
    14641 cctagcacat attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt
    14701 tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg
    14761 gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag
    14821 tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga
    14881 aaggatccga cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat
    14941 agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc
    15001 tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt
    15061 tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta
    15121 gctgtgccat atcctgcatt agtagcgaaa tcatagccag agaactgctg atcgtattct
    15181 ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag
    15241 ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca
    15301 atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg
    15361 gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc
    15421 gacaaggctt ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc
    15481 ttgctgtcgt tgagaccttt aatcttacaa tttttaggta aaataacggc cgcagcgact
    15541 acaggaccag caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct
    15601 tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat
    15661 tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc
    15721 ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg
    15781 atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt
    15841 gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc
    15901 gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt
    15961 gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt
    16021 aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca acttaagtgc
    16081 aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga tttccagatc
    16141 tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc
    16201 aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccaat
    16261 aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc
    16321 agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt
    16381 gatagctagc gtctggattc cttgtgattc aaaatactga cgccattcct tggtcattgc
    16441 tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt
    16501 ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa
    16561 atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa
    16621 ccattgaata gtagccattg agttttttcc tttcgtagca aggatttaga tcccctattt
    16681 tattttacta tagtttgaac atagagagtt ttcaaatgaa tgatgtccaa acagttcttg
    16741 ttttatgaca tagaaatcta ctttatatta tatcatgcct tctttatttt gtccgatgat
    16801 agccttttac cctatctttt agcctatctt ttaccctata tagaaaaaag ccatcaaatg
    16861 atgacttttc agagggagca aaaaactgtt ccttctatat tctaaacatt taaatgtctt
    16921 ctttaaacag tttattaaag aaaccgtctg tgtttttaag aagggctttg aagaccttag
    16981 atttaagagc aacagtgtga gagaagtcat ctggtttctt caaatcttct tcaactgctt
    17041 tatcaaataa aggccttaac tcatcatagt tactgatatg gacgccatca atatcgatag
    17101 cctcaaaacc tttcttagct ttagcaagaa cttccccgta ccaatgtctc ttccactctt
    17161 caagagtatt aaagtttcct ttcgatactt tattaattat tagcttatcg cttagtaaac
    17221 cgtggttgtt tttatctgct tctgctttgt atttatttga tacataacta ataaagccat
    17281 tttcataacc ataatagccc cacatacgga aagcattgtg cttaaatgat aatgaaccag
    17341 gagcaccttg actcgtattc ccaccgtaaa ttcctgccat catattgaca tttacgtaag
    17401 ctgagtttgg tgtaaaatct tctggtctat aacgtccatt acctggattt ccatgttttg
    17461 tcatgaagtt attatccact aaatcattga cgctagataa agtcattacc ttttcttcat
    17521 ctttcaaatc acggatacta tcccattggt ttggacctaa aagatcatta tactgaatct
    17581 tagagcgcat ttctttgtca atcttcttga accacttact attgtctcct ttaattttag
    17641 gaagtacagc atcagcttct acatgatcaa gcaacatcat agcttcattg tagtttctca
    17701 tgtagcggtc aatgtcatca cgtgtcttta atttgtcagg atctgggttg taccattggt
    17761 taccatcatt tggacgatgg taagccatgt taattccaag tgcgccgtat tcaccattag
    17821 tcgttgagct gtcaggtgtt tgcaacatac cttgagcata ggcttcaacg tctgtacctt
    17881 gacgatgctt atgaccaccg aagtaaagca ttctatcgtt tacgtgtgtt gtttcgtgag
    17941 taaaggctga aataccaaat gggctaatca tatccgtcac cataaacaag accttgtcat
    18001 cattatttgg attagggaat attgatgcca tagcgcccat acgccagtct ctatcatggt
    18061 gtcgccatgt tggaccatat aattcacgaa ttggagctat agggttacct ttactgtcaa
    18121 atcctcgacg acctacagga gaaccattgt aggtctggtt atcccaaact ggtgtcggta
    18181 ccatattttg actcttaaga agtctatcac gaacattagg cagagctaat ctggaccaga
    18241 aatctaaata agtttgttga gcatgtgcaa cttcatcaat cttagttttg aactcattac
    18301 gagcttcttc tgtatgtttt ccatatttct caaatgaact gtacgccatc gtgttatatg
    18361 ttgaaattaa gaacatatgg gcatctttaa gcgttagaag tggtaaaatc atacgaccat
    18421 gaacaccgtt atctaaacca tcgaacacac gatgacgttt atctttcaac tctgtatttg
    18481 ttgtcttagg ttctgaaaca taaacattct tagctgagtg gataaaccaa tcattgatgt
    18541 ctttatcctc tgtaaacaga cgcatgttgt attctaagaa gttacgcaaa ttacttttac
    18601 cagtattacc tgcgatgatt tcacggtaag catcctgagt ccgatcccct ttcaagttct
    18661 tttcacttga accgatgttg atgagtctgt caataacact tggtgtttta ccataaaaat
    18721 caggtttgaa catcatgatg ttttttatac ttatgtcacc gtatttgata tcatagtaac
    18781 gattgagata agtcagagcc atcatgattt tagctttatt ggtttccact ttcttgagaa
    18841 gtgattttat cgcagcttca tcaccattca attgatggtc ttcattttcg accaaggatt
    18901 tgactaactt atctagattt tgcttcactt cggcaaagct ttcttctaag tatagatctt
    18961 taatataacc attcttacgt tcatccgtat tctctgcagg tttatcacgt ctactcatta
    19021 aatctcttac ttcttgtgaa atcaattcca cacttgataa ttgagattta acatcagcaa
    19081 tcaatttatc acgattttta acaaccatat tcggtgtata aacaacatca ccaagaccag
    19141 atacactata ttcacgcact tgttggactt tagaatcagt attcttagta acatccattt
    19201 cttccttagt accatcagca tagtgaacca taatcttatc aatatctgat aaatcggtca
    19261 cgaattgacc atccttcatc cccgtaacag aaaggacttc tttcttagct aagtttgaat
    19321 cttctgcaag tttgttacct tggttgacaa tccattcttt attataaaat ggttgaagtt
    19381 tctcaatatt acgataagct aaatcacgtt cggatttgta gtcttgagtt gacttatatt
    19441 catcttctct tctggttaaa cgatttaagc gattgaccac aggttcgttg atttcgtatt
    19501 tatcagcagt aagtccaaaa tttgcaattc tcttattagc ttcatcttga ctaatttctt
    19561 taattttgtc acgagaacgt ttgtatgaat gcttacctga actgacacct ttgacaacaa
    19621 agttacgctc taaccagcca tttgtgaaat aaccaccatc gtagtccaaa tcggaagaac
    19681 caaagaactc ttcaccattt tcaactctca tcattgaaat attatcttca agtttaccaa
    19741 aaggaagatt gctattgata aatccacctg tttcaaacaa aactttagtc ttaatggttc
    19801 ctttggtgac tgatttacga attgaaccgt atttaccaat tcccatagag tcgttaccat
    19861 tatctgtttt agcaactaaa ccacctatac gggctctgtt agcaacaata tcagcctcga
    19921 catatgcttt tgcaagatta cctctccaaa tctcaccggc aatgccagcc atatattgac
    19981 ctttatcacc aacacctgta agattaccga tgaaggctac atttgtcaac tgaccaccac
    20041 tatcgatttt attgacgata cccgcaatat tgttattagc aactacatta ccagttacct
    20101 taacatcttc aacagttgca tttttcacca tattggcaac aggtgctatt ccgtcagccc
    20161 aaggcatatt gatatccaca ttacctaaat taatattttt cacagaacca ttttcaacac
    20221 ggtcaaataa gggacgggca atgttatgaa ttgtatattg tttaccatca acacttgata
    20281 gatgtccctt aaacgtacct ggaacatatt gtttgttagg tgttggtaca ttcgttgcat
    20341 tcaaatctgc tccgatttta aatgtaccat ttttatcagc attcatggca tctactaact
    20401 ctttaaagtt ataataaacg tcatcaactt ttggaactgg tttttcaata taatgaacat
    20461 acttgttacg aaccttcgtt gggtctgtat gttgaatcaa atcttgagct tcggcagtga
    20521 ttttataaag tttcttacct tcttcagtca cttcttcaat tttatcaact gctaaacgtg
    20581 ttactttatt atcacgacta gtaattttta agtacatttt cttcacatct tcatctgaag
    20641 gtttttcagt cataaaatca ctaggtgttt cagtaccatc gtcatttacc ttcactaaat
    20701 tagtagatgc gatattttta atttcaactt ttttcaaatc caagcgaagt ggtttctctt
    20761 ctaatgttgc agtttcttct cccttgccac ggtcataggt catagtggtc tctatcttat
    20821 agtccttgta gaattttaaa tcttctacct gcttatctaa ttgctctgaa gtcaaatcta
    20881 ctgttttgac aatttcattt ccatctttaa ttgtcgcagt aattttattg attgtgactc
    20941 catctgtatt aactaaatga taagaaagag ttgcggatcg gtttaataca tttgtatttg
    21001 ttctatctaa ggtcaaaaca ggagccgttt tttctttagg tttttctttg gtacctttta
    21061 caagaatttt aggcttcatt tctttcaaaa tagttactgt ttcaactggg tcactgattt
    21121 ttttgccatg taactcttca tagctagtaa caatttgacg ttcgccatcc tcaccaactt
    21181 gtctaacaga atcatcgcct ataaatttgc taggatcaga ttcttctata gtggttttag
    21241 gaatagtctc tgtccgaata tcggtatgta aagaaggcaa ctcttctctt tctgatgcaa
    21301 cttctgaaac tgtagatatt ggttcagtat actctggaat gtcgctaaca ggtggctcaa
    21361 tcaagtttcc attttcatcc actcctgttg tacctactgg ctcagtatat tctgggatgt
    21421 cgttaacagg tggttcaatc aagtttccat tttcatctac tcctgttgtc cctactggtt
    21481 cagtgtatgc tagtttctca tgaacttcag gctcaacaag gtttgcacct attggttgcg
    21541 tatagtcagg cttctcatga acttccggtt cgcctttctc tgttacaact ttgggttgct
    21601 caactggcga aacagttgat gctggagaaa ccgacgaaac agttttatca tcaagctcca
    21661 agtaaccaac atatctgtaa ccagaaattt gcaacacacc atcacgtcca gactcatgga
    21721 tgttagcatt caaattaagt gctgaagcag ttgatagtgt aactaaacct gtcgccccta
    21781 caatcaaaaa tgtagctatt tttttatttc tattatcttt tgtgataatc acaataagac
    21841 tcccgatagc taacaaaccc aatgcagtca taatagattg agaacttcct gtgtttggta
    21901 gtgcgtcttt ttcataatcc aaagcatatg actctttgga ttcatcaggt ctaccttgtt
    21961 tgagttgatc acgttcagtt tgtgtcaaac tactataatc taagtaatga taagtcgatg
    22021 caccaacaac tgacggtgca aataaaagac tccccaagaa taccgaacca acaataccct
    22081 ttattttccg aatggaaaat ttatcttttt ttaataatga caattctaat cctccacctt
    22141 cactttttat ttcctaatag taaacactat tttttattct caaaaattga acttctaaaa
    22201 tcaccggttt ggtcaagata agctttaaag attgcttttt tcagtttaag aactctacta
    22261 tttgtctcag gatataattt ggcaacttca tcctcagcat caaattttac tgcatcttca
    22321 atcatttttt caagtctatt aatattatca atagtcactt tctgttgtcg agcccaagaa
    22381 ccgtttggat cgataaaact aactttattt aactttccaa atttatcttc tctttcttta
    22441 tacatatctt tcttgaaatc tatccaagaa ttatactggt tattaaatac ttttgaaaga
    22501 acaatttcat cagtaactaa acctatttgt ttaccatatg atgtaataac ttttccttga
    22561 gctttcgctt ctttttcata ctgattagaa atatatggaa ccataccgtc tttgtacccc
    22621 ttggctgcca ataactcaaa tgcaatacgt cgtcccatta aatctcctgg tgttcctatt
    22681 ttactgctca atgctgaata aattggtgag aatagattaa ttgtatagta gccattccgc
    22741 ttataagttg cttcatctac ataacctctt cttgttataa tatcatgttc tatcaaactg
    22801 ttaaatgtag ttaatttagt aagttcttct ggttttaatc tacgtacaac attcgttgca
    22861 taaacagaat ttccatcagg atcaggttta tattcatttt ctatttttct taataaatca
    22921 tatttttgat ttgtatctaa tttagctaca gctttacctt ctagtatttc aagcatgtat
    22981 attacatcaa acatattatg catatactta tttagatcat caacacttcc aaatcgttga
    23041 gttggatctg ctacttgaag ccttgttgat tcttctgatt gatcatattt taatatggaa
    23101 ttaatagtga ctgttggatc attaggatga tcaggagctt gtagcagtcc tttagcataa
    23161 aactctggtc caagtccatt tcgtcttcca tagcctccaa gataaatttc tctatctgag
    23221 ttatgtgtca tttcgtgtgt ataagttacc gcaccatctt tatcaagcat gcgatatgcc
    23281 atataataga atgcatcccc tgtagcatat gctccattag aattatgaac aacattattt
    23341 cccgctggac cgaagaaatg ttttatagct ggatgattag tttcaaaagt tgcttgatat
    23401 gtatctttat cttctttttc atctgtacca aatctaaatg catcatagac tagaacactt
    23461 ctatataatt tttctttatt tttatcatct agtattctat accaataatc atagtgatct
    23521 ctaaatctaa cagccgcttc tttagctttt ttctcaacat agtcatttaa atcagttcct
    23581 gctggatgtt ctttacttct atatctatca taagcaccga aacctatagt cgaaatgttg
    23641 gctataataa acaccgattt ttcaggtaat gttaatagcg gcaacaccat acttggatat
    23701 ttccaagatg ggctagttaa tctatcatat actccaattg aatatggact accagctatt
    23761 gattgcttat cacttacctc tttaatagta gatttttctt ctacaatata tgctttagtt
    23821 tgttctttaa accactcatt atttgtttta tctggtacaa atgcttttct atatttctct
    23881 aatgcatcaa ataaattatt agtcttataa tttttcgcta ataaaacatt ataagttata
    23941 acattatttt ttgctagtaa gttattatat cccgatttac ctagttcgat aacattatct
    24001 aacgctgaac tatttgattt accgaagaaa tccaagtggt acatgactaa atctttcgct
    24061 tttgtatcac gatatttgaa gtcgtaccaa cgctctaagt atgttaatcc tagaagtaaa
    24121 gcttctttat tatttttaat tttctcgatt acataattat ctattacctt attgttattt
    24181 tcagctattg cagcatctgc agtaagaagt tttgtcaaac tatctttcaa attagttttt
    24241 gtggtattga attgttcttc taaatataac tccgttaaac taacatcctt agaaacatct
    24301 aatacttttc taattgcctc tgatttatat tctacactat ttaatgctgg taatacttca
    24361 tctaaaatat tttgataatt gcgaagtaat gtattcggtg tataaattaa gtttgtaccg
    24421 cctattctat actctgctac atttgaaaaa tcagtttgat aatttacatt aagtgtctct
    24481 gatgtattat ccgcgtaata tagtaatagt ttatttatac ttgatttatt tttgttaata
    24541 tcactaatta cttctttatc tttcataggg actactgaca ataattcttt attataaaga
    24601 ttactacttg tctctactaa atttccgtac ttaacaattg tttctctatt ataaaacggt
    24661 aatagttttt caatattttt atatactttt tcttttgatg aatcagcatt ctcaagattt
    24721 ttatagtcag ttacatatct agaagagaaa ttaaaatctt ctgttttaat agtattttta
    24781 gatacaaaag tagctttttt ctcttttatt tgtgcatctt ctaatacttc tcctctttga
    24841 acagtagaat ccttagttaa gatttcatca tcttcttgta ctacgttcac aaccttatta
    24901 tttttattac tgtatgtgcc atttgctttt ataccattaa aattataacc tgcaatagca
    24961 ttaccattcg ttacattaac atcgcttagt acattagaaa gtcgaccgga tttttctaat
    25021 cctccaaccg gatcccaaag attaccaact actccaccaa cgtttgcaaa acgttgaaca
    25081 ttatttagat ttccttcagc ataactatta ctaataagcg cactattttc tactgcacca
    25141 actattccac caatagactg gtctccttgt gttgcatttg aagataaatc gattgatgcg
    25201 aacgacttat ctattaatcc cctcggacca gaaagtttgc ctactaaacc tccgatttga
    25261 taactagcaa ctgttttata tgtattagtt attctacctg tatagctact gttagaaata
    25321 gtagaattat taacttgtga tactaatcct cctatgctac gttccccagc tatcgctcca
    25381 tcagcatgaa cgttatcaat atgagtattg ttatttgctt ctttcgcaag tgttgcagta
    25441 tcgtcctttg cggaaatatt aacatctttt agtgaaagtt tttctactgt agcaccattt
    25501 aattccccaa ataatggttt tttcaaatta taaatagcat aatatttctc attatttgtt
    25561 cctactaata ttccatggaa tacattattc acataacttt cttgaccatc tggaagttca
    25621 acttcacgag catccatagt tgctcctaaa cggaatgtgc cattaggatt gctattcatt
    25681 gcatctacta aatttttaaa tgatgtatat accccagttt cactttgctg agtttttggt
    25741 aaatagtatg tataattttc tagtacatta ttattttcat gttgtatcag actatttgca
    25801 cttgctacta tcttataaac atctctatta tctttagtat cattagtaat gcttgtaact
    25861 ggtagcatca catctttaaa gttctctgat ttaactttca taaagtaatt ttctgcatta
    25921 cttggtaaag aagcaagtga agttacatgt cgatacttat taccatcttt tgaatatagt
    25981 tctacagaag atatatttct aagttctaat ttcttaataa cttctttttc atctttagcg
    26041 tcatcttttt tctcatcttt atgacgataa agttcatcgt atactggtgg aatttcatta
    26101 cctgctataa tactcttaat ccaagctaat tgtgtaggag ataaaatcaa tccgcctgag
    26161 cgattttgtg ctccattttg atgcacacca ataacttcac cattagcatt aaatattcct
    26221 ccaccactca taccaggatt tccaccttga tattgaacac cgtaggtgtt attcgcatat
    26281 tcttgttcca tttctaccgt agcatctttt aagtgcgtat atttcccagc tggatatcca
    26341 tgaacattta gtttgtcatt aagatttact ttcgaataat ttttaactaa ttctacatgt
    26401 tctctgccag ttgtttcagg tagcttaatc actgctaaat catagataaa tccttttgga
    26461 taatcttttt tattataaaa atgaatattg ttagcagtaa atgttccttt ttgtccatca
    26521 ggagtcaccc actcatatac gtttttagat ttatcacctc taaattcgcc agtagtatta
    26581 tcagtagaat tattaatgaa attatgtgct actgttaaaa gtacatttgg tgcaataaaa
    26641 gtagctgatc ctactccagt aaccttcgac gaatctgtaa taaagttcat attaattaat
    26701 gcactagatt ttttctgaat actcatttct tctggtgtat tagtattttc attatttggt
    26761 ttagtatctt ctgcactagg ttgttcgatt ttaccagtat attctttcag tgcttctact
    26821 ttttctggtt ctactattgc tccggcttgc acccctgtgt attctggtag tggtgctatc
    26881 tgctctggtt caacaatagc gccagcctgc acccctgtgt attcttttga tggttctact
    26941 ttttctggtt ctactattgc tccggcttgc actcctgtgt attccttcgg tgcttctacc
    27001 ttctctggtt cgactatcgc tccagcctgc actcctgtgt attccttcgg tgcttctact
    27061 ttctctggct cgactatcgc tccggcttgc acccctgtgt attctggtag tggtgctacc
    27121 tgctctggtt caacaatagc gccagcttgt actccagcat attccggttc aactttttca
    27181 ggttcaacaa tagctccagc ttgtactcct gtatattctg gtagcggttc tacctgctct
    27241 ggatcaccct tgtcagtcat gactgcctct ggtaacgctg gttgaacttc tggtacgcct
    27301 ttatcactta ctacagcttc tggcaactct ggttggactg ctgactcacc tttgtcggtt
    27361 aatacagctg ctggtagttc aggctgaatt gcgggttcaa caatagctcc agactgtact
    27421 tccttatgtt ctgcaccagt ctcagcttgt tcctttataa cttgagcttt tttagtacct
    27481 ttttcgacta ttcttgaaac aggcgcagtc gttgaagttg aaataatttc tcgtgaaact
    27541 tcttcattgt ttacagaaaa tattctgacg atttcaactt tcttacctaa tgcaccttct
    27601 tgttttactc ttacagttcc ttctgctaaa tcaggatttt cttgaatttc ttcttgaaaa
    27661 tctatttttg tttctatagt ttcgtcacga tataagagtt ccggtttgtt caactgacct
    27721 gatagcactt catcctgtgg atttaatgta tttaccccag tcttttcctt tggagaaatc
    27781 ttctcctctt tcttcgtttc tagattctta tgttcggcta attgttcttg agaatctgaa
    27841 gattgtttct cttcttttct tggattgatt aattcagtag agaaaggttt ttcaactact
    27901 tgaacttctg tcggcttagt tgaagaaaca ggtgtttgtt cctgaatagc ttgtactgtt
    27961 gatggatggt ctacaaaatt tggtgtaaca ttataatcca ccttttgttg ttttgtagga
    28021 gtggctgctg atttttcttg attacttact tcaaaatcag aagtcgtttt tccctctttg
    28081 atatatccaa tataagtgta acctgaaatc tctttaggaa gaggtaattt ttctccagag
    28141 gtcaattcat agtccgtatt gtaatttagc aaaagatgat tttctaaagc atggactgaa
    28201 actaagacac catttcccat tcccgcaacc aatactaaat gtaataccgt tttattctta
    28261 acctttttct tggaaacagc aaaaattaaa attcccagag cagctaagct agcaccagca
    28321 actagggctt gcctctcatt cttgcttcca gtatttggta attccgccag ttgattttga
    28381 gaatttaact tataaacaag ataataagtt tcattatcat tctccacgta tgtcggaata
    28441 tcatagacaa gctgcttctt ttcttctgat gatagctctg aatctgccac atatttatag
    28501 tgaactcccg cagtttcttg agcatccaca gatgaactag ctaatacaga cataaaaaat
    28561 aaacttgaaa tcgttgcaga tacaagtcct actgataatt ttctaaatga aaaacgctct
    28621 tgtttttcac caaaatactt ttccattatt cctccttgaa ataaaattta tatatgttac
    28681 aaagaccttt attatattag tgtattatct attatctata gaaaaggcag tataccttaa
    28741 ttatactctt aatttacaaa aaagtcttaa aattgagatg cgctttcata ctttgtttta
    28801 tattatttgg gggtacaata acacctacca tgaaatttac acggtaggtg ttactcatat
    28861 cactaatcgt tctaaaaatg gtttgaggca gttgaggaga attccttcta tccagcttcc
    28921 ttgtgctgat gagcgatggt cttcctgcag gctttttttt agaaaatctc ggacttgttc
    28981 tggtgcgatt tcaaattcaa aggctttcat tttatagaaa aagtcgatga gatgatcgga
    29041 caggtattca gttgaaaagg gtacttcacc actttttcga tattctaata agagcctaga
    29101 aaatcgagct ttttcttcag gaagctcacg aaaataggaa ttgaggagcc aagtctgctt
    29161 ctgttttctt tcaattggat cctgactggc aattcgttgg tctttttcca gctctttttg
    29221 gtattgtttg gccttgatag cccgttctgc tctattttta ccaaaaagaa ttttttccca
    29281 cttgcgttct tcttgagtca gggtctctgt aaagccaaag taatcttgat aagcacgctc
    29341 tgcgggtccc atggctagaa ccagattgtc tgcatattgc ttggcgattt tatccctctt
    29401 cttgcgttct ttctctgcct ggatacggag ttcttgttcg tagtcaattt tctccttgcc
    29461 tagcttgaca aggtagagtt ggtcatccga tttcccaagt aaaaagggtt tgatacactt
    29521 ttcaaggact tcttccatcc gagccttttt ctttggttcc gccttggtcc aacttcctcc
    29581 ctgaaagact tctaggaaaa gctggtagtc tctctcaggc gcaaattgat tgccacgatt
    29641 gggtttgaaa acaccttttt cccagagcca ttttagaagt cgctcgtcaa agtcactttt
    29701 attgaccttg attttttctt ttttctgagc ttttctggtt agattttcaa cctttctgag
    29761 cagtttttct tcctcttcca attgctggtc aagggacaat cgatgaaaat gacgaacaca
    29821 gtcgctacca attggaaaga ggcgttggcc tgtgacaccg ttaaagagtt cataagcgta
    29881 tttgatggca tttccacaga cacaattgct acggccgata ccgttaaaaa tcaaggaaac
    29941 ttcattccat tccttggtag cttgttccca agtatccgct ttcgaagcct gtaaaactgc
    30001 atcgtgcagg gattttctaa ctggaagtgt catgaggtct cctttctaat actcaataaa
    30061 aatcaaagag caaactagaa agctagccgc a
//
LOCUS       DAVBNN010000021        29868 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBNN010000021 DAVBNN010000000
VERSION     DAVBNN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.021"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..661
                     /locus_tag="VQ847_001011"
     CDS             <1..661
                     /locus_tag="VQ847_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050362.1"
                     /translation="GFSWTHFETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIY
                     IYQSRKKYQEAFLSLNNILMVAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPI
                     VVLMVLPRLKEMNGDMIHAAYDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDF
                     AVTFFVTGNGFSTLSVEIYSRARKGISLEINALSALVFLFSIILVVGYYFISREKEEQ
                     A"
     gene            658..1728
                     /locus_tag="VQ847_001012"
     CDS             658..1728
                     /locus_tag="VQ847_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3050363.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            1989..2228
                     /locus_tag="VQ847_001013"
     CDS             1989..2228
                     /locus_tag="VQ847_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050364.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            2503..2988
                     /locus_tag="VQ847_001014"
     CDS             2503..2988
                     /locus_tag="VQ847_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3050365.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            3010..5628
                     /gene="alaS"
                     /locus_tag="VQ847_001015"
     CDS             3010..5628
                     /gene="alaS"
                     /locus_tag="VQ847_001015"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3050366.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(5717..7171)
                     /locus_tag="VQ847_001016"
     CDS             complement(5717..7171)
                     /locus_tag="VQ847_001016"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3050367.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            7350..8099
                     /locus_tag="VQ847_001017"
     CDS             7350..8099
                     /locus_tag="VQ847_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050368.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            8080..9714
                     /locus_tag="VQ847_001018"
     CDS             8080..9714
                     /locus_tag="VQ847_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050369.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            10401..11564
                     /locus_tag="VQ847_001019"
     CDS             10401..11564
                     /locus_tag="VQ847_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3050370.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            11561..12238
                     /locus_tag="VQ847_001020"
     CDS             11561..12238
                     /locus_tag="VQ847_001020"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3050371.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            12228..13082
                     /locus_tag="VQ847_001021"
     CDS             12228..13082
                     /locus_tag="VQ847_001021"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3050372.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            13101..14168
                     /locus_tag="VQ847_001022"
     CDS             13101..14168
                     /locus_tag="VQ847_001022"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3050373.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            14178..15344
                     /gene="aroC"
                     /locus_tag="VQ847_001023"
     CDS             14178..15344
                     /gene="aroC"
                     /locus_tag="VQ847_001023"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3050374.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            15354..16457
                     /locus_tag="VQ847_001024"
     CDS             15354..16457
                     /locus_tag="VQ847_001024"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3050375.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            16468..16806
                     /locus_tag="VQ847_001025"
     CDS             16468..16806
                     /locus_tag="VQ847_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3050376.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            16898..18181
                     /gene="aroA"
                     /locus_tag="VQ847_001026"
     CDS             16898..18181
                     /gene="aroA"
                     /locus_tag="VQ847_001026"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3050377.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMLGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            18174..18650
                     /locus_tag="VQ847_001027"
     CDS             18174..18650
                     /locus_tag="VQ847_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3050378.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            18647..19495
                     /gene="pheA"
                     /locus_tag="VQ847_001028"
     CDS             18647..19495
                     /gene="pheA"
                     /locus_tag="VQ847_001028"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3050379.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            19492..20766
                     /gene="psr"
                     /locus_tag="VQ847_001029"
     CDS             19492..20766
                     /gene="psr"
                     /locus_tag="VQ847_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3050380.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            21045..21890
                     /locus_tag="VQ847_001030"
     CDS             21045..21890
                     /locus_tag="VQ847_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3050381.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            21880..22983
                     /locus_tag="VQ847_001031"
     CDS             21880..22983
                     /locus_tag="VQ847_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3050382.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            22985..23971
                     /locus_tag="VQ847_001032"
     CDS             22985..23971
                     /locus_tag="VQ847_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3050383.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            23987..25420
                     /locus_tag="VQ847_001033"
     CDS             23987..25420
                     /locus_tag="VQ847_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3050384.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            25449..26483
                     /locus_tag="VQ847_001034"
     CDS             25449..26483
                     /locus_tag="VQ847_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3050385.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            26683..27420
                     /gene="mecA"
                     /locus_tag="VQ847_001035"
     CDS             26683..27420
                     /gene="mecA"
                     /locus_tag="VQ847_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3050386.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            27571..28857
                     /locus_tag="VQ847_001036"
     CDS             27571..28857
                     /locus_tag="VQ847_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3050387.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            28859..29728
                     /locus_tag="VQ847_001037"
     CDS             28859..29728
                     /locus_tag="VQ847_001037"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3050388.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
BASE COUNT         8717 a         5589 c         6691 g         8871 t
ORIGIN      
        1 aggttttagc tggactcact ttgaaaccat gtttggagat gggagactca tgctgatttt
       61 ggctcagaca tttttcttgg ccttcctatc agccttgata gcgaccatta tcgggacttt
      121 tggtgccatt tacatctacc agtctcgtaa gaaataccaa gaagcctttc tatcactcaa
      181 taatatcctc atggttgcgc ctgacgttat gattggtgct agcttcttga ttctctttac
      241 ccaactcaag ttttcacttg gctttttgac cgttctatct agtcacgtgg ccttctccat
      301 tcctatcgtg gtcttgatgg tcttgcctcg actcaaggaa atgaatggcg acatgattca
      361 tgcggcctat gacttgggag ctagtcaatt tcagatgttt aaggaaatca tgcttcctta
      421 cctgactccg tctatcattg caggttactt catggccttc acctattcgc tggatgattt
      481 tgccgtgacc ttctttgtaa caggaaatgg cttttcaacc ctatcagtcg agatttactc
      541 tcgtgctcgc aaggggattt ccttagaaat caatgccctg tctgctctag tctttctctt
      601 tagtattatc ctagttgtag gttattactt tatctctcgt gagaaggagg agcaagcatg
      661 aaaaaaatct attcattttt agcaggaatt gcagcgatta tccttgtctt gtggggaatt
      721 gcgactcatt tagatagtaa aatcaatagt cgagatagtc aaaaattggt tatctataac
      781 tggggagact atatcgatcc tgaactcttg actcagttta cagaagaaac aggaattcaa
      841 gttcagtacg agacttttga ctccaacgaa gccatgtaca ctaagataaa gcagggtgga
      901 acgacctacg atattgccat tccaagtgaa tacatgatta acaagatgaa ggacgaagac
      961 ctcttggttc cgcttgatta ttcaaaaatt aaaggaatcg aaaatatcgg accagagttt
     1021 ctcaaccagt cctttgaccc aggtaataaa ttctccatcc cttacttctg gggaacctta
     1081 ggaattgtct acaacgaaac catggtagat gaagcgcctg agcattggga tgacctttgg
     1141 aagccggagt ataagaattc tatcatgctc tttgatgggg cgcgtgaggt gctgggacta
     1201 ggactcaatt ccctcggcta cagcctcaac tccaaggatc tgcagcagtt ggaagagaca
     1261 gtggataagc tctacaaact gactccaaat atcaaggcta tcgttgcgga cgagatgaag
     1321 ggctatatga ttcagaataa tgttgcaatc ggcgtgacct tctctggtga agccagccaa
     1381 atgttagaaa aaaatgaaaa tctacgttat gtggtaccga cagaggccag caatctttgg
     1441 tttgacaata tggtcattcc caaaacagtt aaaaaccaaa actcagccta tgcctttatc
     1501 aactttatgt tgaaacctga aaatgctctc caaaatgcgg agtatgtcgg ctattcaaca
     1561 ccaaacctac cagcgaagga attgctccca gaggaaacaa aggaagataa ggccttctat
     1621 cccgatgttg aaaccatgaa acacctagaa gtttatgaga aatttgacca taaatggaca
     1681 gggaaatata gcgacctctt cctacagttt aaaatgtatc ggaagtagga gataaacgta
     1741 agaagacgaa tcagtcaagc tggttcgttt ttaaggaata gaagtcagtt tttagagccc
     1801 tatctttttc tattctagtt gtttatttgt ttatttgctt atttgcttgc ctagtagtat
     1861 actaagccta tactcttcaa accacgtcag cgttgccttg ccgtactcaa gtacagcttg
     1921 aggctagctt cctagtttgc tttttgattt ttattgagta ttaaccttac agaaagcggc
     1981 aacaaataat gaaaatgtct acttttttca aaaaaagttt ctggccaacc tttatgattg
     2041 ttaaccaaac tgctatacta ttccatttaa aggatggctt ggatcgacaa tacctaacaa
     2101 ctgagtccat atattgggtg ataggcacct ttatatttgg aaatattcta gtagctgtgt
     2161 ttagtaatat gaaaatttgg gataaaaaga aaaatggcag taagaaaaaa tatatcctga
     2221 aaaagtaatc agagatgtag ggaattggtc taattcaacg gagatcattt ccagttgacg
     2281 caagcttaaa aaaacgttat aataagaaag ttgagaattg attttcactt gtcttagtcc
     2341 agagaaatgg cggtgctgcg agccatctaa gctaggaagt catgctactc aatcatacaa
     2401 ttgcataaga acaagagaat gacaagttca ttgaatgaag gtggtaccgc ggtttttcgc
     2461 ccttcgtgat atgagcttgt cttttgattt ttggaggtgt tgatgaaaac atttcttgtc
     2521 aaacaaaagt ttcgtcttgg aggcgaacgc ttcgctatca aggatgacag gggagaaatt
     2581 gcctatcagg tggagggatc attttttaag attcccaaaa cttttaccat ctatgatgcg
     2641 gctggtgaac aagtcagtca gatcagtaaa gaaatcttga ccttgcttcc tcgttttgag
     2701 attcagcttc gggatggctc gagttttgtc attcgtaaga agttgacctt ctggcgagat
     2761 aagtatgagt ttgataatct aggtcttcgt atcgagggca atatctggga tttgaatttc
     2821 aaattgctgg atgatcgcga tcagttgatt gcggaaatta agaaggaact cttccatctg
     2881 acctctacct ataccgtaac ggttcttgaa gacgcttatg cagacctagt catttccctc
     2941 tgtgtcgcga ttgactatgt ggaaatgctg gaaagccaat cacattaaac aagtgaataa
     3001 ggagacaata tgaaacaact atctagtgca caagtacgcc aaatgtggct tgatttctgg
     3061 gcgaccaaag gtcactcagt agaaccatca gtaagtttgg ttcctgtaaa tgacccaact
     3121 cttttgtgga tcaactctgg ggtagcaacc cttaagaaat actttgacgg gaccattatc
     3181 cctgaaaatc cacgtattac caatgcccaa aaggctatcc gtaccaacga catcgaaaac
     3241 gtagggaaga ccgcgcgtca ccataccatg tttgaaatgc tggggaactt ctctatcggg
     3301 gattacttcc gtgacgaagc tatcacttgg gcttatgagc ttttgacaag ccctgaatgg
     3361 tttgatttcc ctgctgaaaa actttacatg acctactatc cagacgataa agattcttac
     3421 aaccgctgga ttgaagtggg agtggatcca agtcacttga ttccaattga ggacaacttc
     3481 tgggaaatcg gtgcgggacc ttctggacca gatacagaaa tcttctttga ccgtggggaa
     3541 gcctttgacc cagaaaatat cggtcttcgc ctgcttgcag aagatattga aaacgaccgt
     3601 tatattgaaa tctggaacat cgttttgtca caatttaacg cagaccctgc tgttcctcgt
     3661 agcgaataca aggaattgcc acataagaac attgatacgg gcgctggttt ggagcgtttg
     3721 gtggctgtta tccaaggggc taagaccaac tttgaaacgg acctcttcat gccgattatc
     3781 cgtgaagtcg agaaattgtc tggtaaggtt tatgaccaag atggcgacaa catgagcttc
     3841 aaggttatcg cagaccacat tcgttctctt tcatttgcta tcggtgatgg tgcccttcca
     3901 ggaaatgaag gtcgtggtta tgttcttcgt cgtcttctcc gtcgtgcttc tatgcatggt
     3961 caaaaattgg gtatcaacga acctttcctt tacaaattgg ttccaactgt tggaaaaatc
     4021 atggaaagct actacccaga agtgcttgag aaacgtgact ttattgagaa aatcgttaag
     4081 agcgaagaag aatcatttgc ccgtaccctt cactcaggtc aacactttgc ccaaggcatt
     4141 gtagcagact tgaaagaaaa aggtcaatct gttatcgctg gttcagatgt cttcaaactc
     4201 tatgatactt atgggttccc agttgaattg actgaagaaa tcgctgaaga agctggtatg
     4261 actgtagacc gtgaaggttt tgaagcagcc atgaaagaac agcaagaacg cgcgcgtgcc
     4321 tcagctgtca agggtggctc aatgggtatg caaaatgaaa ctcttcaaaa catcactgta
     4381 gaaagtgtct tcaactacaa tgctagccaa ttgtcttcta aattggtagc tatcgtggcg
     4441 gacaatgcag aagtagaagc tgtttcagaa ggaactgcct ctcttatctt tgcggaaacg
     4501 tcattttatg ctgaaatggg tggacaggta gctgactacg gacaaatctt ggatgagtca
     4561 ggtaaggttg tggctactgt gaccaatgtt cagaaagccc caaatggtca agcccttcat
     4621 acagttgaag tccttgcacc gcttgccttg aaccaagaat ataccttggt aattgatagc
     4681 aatcgccgtc accgtgtcat gaaaaaccac actgcgactc atttgcttca cgctgccctt
     4741 cacaatatcc ttggaaacca cgcaacacag gcaggatctc ttaacgaagt tgaattcctt
     4801 cgctttgact ttacccactt ccaagcagta actgctgagg aacttcgtgc gattgaacag
     4861 caagttaacg agaaaatttg ggaagcactt gaagtgaaga cagttgaaac ggatattgac
     4921 actgctaaag aaatgggagc tatggccctc tttggtgaga aatacggcaa ggaagttcgt
     4981 gtcgtgacta tcggtgacta ctctattgaa ctttgtggtg gtactcatgt tggcaacact
     5041 tctgagattg gtctcttcaa aattgtcaaa gaagaaggaa tcggttcagg aactcgccgt
     5101 atcttggcag tgactggtaa ggaagccttt gaagcctatc gtgaacaaga ggatgctctt
     5161 aaagctgtcg cagcaacctt gaaagcacct caagtcaagg aagtacctca caaggtagaa
     5221 ggacttcaag aacaacttcg tcaacttcaa aaagaaaatg ctgagttgaa agaaaaagcc
     5281 gcagctgcag ccgcaggcga tatcttcaaa gatgctaagg aagtcaacgg tcatcgttac
     5341 attgctagtc aagtgtctgt atccgatgcc ggtgcccttc gtacttttgc agataactgg
     5401 aaacaaaaag actactctga tcttcttgtc ctagttgccg ctatcggtga caaagtcaat
     5461 gtccttgtag caagcaagac aaaagacctt catgcaggaa accttgtcaa agaattagca
     5521 ccaatcatcg atggacgtgg tggtggtaaa ccagacatgg ccatggcagg aggaagcaac
     5581 caagctaaga tccaagaatt attggatgta gtagcaggta aattgtaatc aagtaaagat
     5641 ctatccattt gggtaggtct tttttgacta caaaaaagcc aaatccgctt ggacctagct
     5701 tggttattat gagctattag atggtattga ctgcccagac acttacggat ctagctgaga
     5761 cagggaattg tccataacct tcctcatcaa ttgtaacttg accttggtgg ttaccaagta
     5821 aatctacaaa ggtttgatta gtccattctt gaccgacaaa cattgacttg ctgttttctt
     5881 ggtcatttga aatcaagact gcgattgggg attgattttc agcacctgaa cgtacccaac
     5941 cgatacagtt agcatggtca aagtagtcat tttgttctcc ataggccaaa tcttttcgga
     6001 tggctaggag gcggtcaagg atttctttga aatcttgttg agcatactgg cctgaaatcc
     6061 catagtagtc tccgtaaaag acacatggaa ggccgtcttg gcgtaacaaa atgagggcat
     6121 aggctgctgg cttgaaccat tcttcaacgg tagactcaag ggcttgtcct cgttgggtat
     6181 cgtggttgtc gacaaaagtc acagacttgt caggcttgag ttcaaccagg ctatctgtga
     6241 aaatgccacg aaggtcatag tttgcgccag cttgactggc ttcaaagaga ttctggtgga
     6301 gacgaacatc gacaaggtca aagtgttctt ccgttttttc gagatagtcc agattggctt
     6361 ccttgtctgg gttccaaaat tcaccaaaaa catagaaatc gtcaccgtat ttttccttca
     6421 tatcgcggat gaagttgcgc ataaagaaag agtcaatatg cttaacggca tccaaacgga
     6481 aaccagctac accagtcgtt tccatgaacc aatcagccca gtcatagatg ttttggatga
     6541 cttcaggatg tttaaagtct aggtcggcat acatgaggta gtcgtagttt ccgttttcgt
     6601 tatcgaccaa ttcctcgtta gcccagccct tgttgtcccc ttggatgaga taaatcccag
     6661 acttacggcg ttttgcatcg tagtctgtac cggtgaagtg gtaccaatgc cagtggaagt
     6721 cattgtaggt atcttggcga ccatagaagg taaagctagt ccagccattg atggtgaagg
     6781 gttctccaag ttcaaccgta cggtctacag gatccacttc gataacctga aaggcttcca
     6841 tgtgatcggc tgcagccttg tgattgagaa ccacatcggc cataggttga attccctgtg
     6901 cttttagggc ttgaatggct tgaagatagt cttctttgaa accatactta gtgcggacag
     6961 tccctttttg gttaaactct cctaggtcaa ataagtcata gacaccatag ccgacatctt
     7021 tttcattggt tgccttaaaa gctggtggca tccagacgtg gctaatcccc agatgagcta
     7081 ggtgtggagc atcttcagcc agacgcgtcc agtgctgacc gtcgtggggc agataccatt
     7141 caaagtattg catgagcgtt tgattttgca tgatttttcc tcttacttgt caatcttgtt
     7201 ctttattcta tcataaagta ttggttagcg caaacgtttg cgtaagaata gaaggaaact
     7261 gttttaacta cttaaaataa agtattgatt ttttgtatca aagtgatagt atagcgatat
     7321 ataatacaga taaagatagg agttgtccca tgattgaatt tcaaaatgtt agtaagttgt
     7381 atggtgataa agaggccttg agtaatctca atttgcagat tgaaaatgga gagattatgg
     7441 gcttgattgg tcataatggg gctggaaaat cgaccactat aaaatcccta gtcagtatca
     7501 tttcacccag cagtggtcgt attttggtag acggtcagga gttatcggaa aatcgcttgg
     7561 ctattaaacg aaagattggc tacgtagcag actcgcctga cttattttta cgcttaacgg
     7621 ccaatgaatt ttgggaattg atcgcctcat cctatgatct gagtagatct gacttggagg
     7681 ctagtctagc taggctattg aacgtttttg attttgctga aaatcgctat caggttattg
     7741 aaactctttc tcacggaatg cgtcagaaag tctttgtcat cggggcactc ttgtctgatc
     7801 ctgatatttg ggttttggac gaacccttga ctggtttgga tccccaggcc gcctttgatt
     7861 tgaagcaaat gatgaaggag catgcgcaaa aaggtaagac agttttgttt tcaactcatg
     7921 tgctagaggt agctgagcaa gtctgtgatc ggattgctat tttgaaaaag gggcatttga
     7981 tttattgtgg taaggtagag gacttgagaa aagacaaccc agaccagtct ttggaaagta
     8041 tctaccttag ccttgctggt agaaaagagg aggtttcaga tgcgtctcaa ggtcattaaa
     8101 aaattagttg atatcaatat cctctattca tctcaagacg ctaatctggc taacccacga
     8161 aagaagcaag ctaaaaatac tggaaaaaaa gtaaatgttt ccgctagagt cctaagttct
     8221 tacatttttt ccagtctctt gatgctcatc ttttttagta ctatagccat tcattttcct
     8281 tttgaggaaa tgcctgttta ttttagtttc atggttgcta ttttactagt gattgccttt
     8341 tcaacttctt taactgcatt ttacaatgtc ttttatgaga gtaaggattt ggcctcctat
     8401 agtccctatg cttttaaaga atcagagatt ataattgcta aaggactgtc tgtcctcttg
     8461 ccagctctaa ctggaattgt accaatccta gcttattttc tagccctcta tattagtcta
     8521 gctccttctc tttggctggg tttgcctttg atgctactgt ccttgacctt attatttgtc
     8581 tctgttactt tagtgacggt agtggcagta catttcttgg ctcagactag ggtcttcaga
     8641 aagtatcagt ctattttttc gaatgtgatg attgggatag gagttctcat acctttaata
     8701 tttatcttct ttcttcagtc gacttttgga agtattgttg acaaagttag agacattcca
     8761 tttctccttt atcctcttca tatcttttac aaaatagcag tggagccttt ttcaatagaa
     8821 gccatattgg gtctgctcgc ttggatagga ctaactctct tcctgcttta tctgaccaaa
     8881 aagaaggtcc ttcctcgttt ttatgacgtg atcctgctta atagtgagga gaaggtcaaa
     8941 aaagaacgtc gcagcaagga gagaatttca accactaaaa agggattttt ccgcatggtt
     9001 ttacgctacc acctcaccct cttgggacag gggactggcg tggttacagt gctttttaca
     9061 agtgctttcc ttccttatct catgatgatc ggtctgattt ccaaaatccg agattctcag
     9121 atagttccag acattcatcc tccatactgg ttacccttgt tttttatagc tctctttata
     9181 gcagttgtca ataacaatat caccagcctg ccttcaattg ccttgtcctt ggagagggaa
     9241 aatgttgatt ttctgaagag tttacccttt gactttgctc gttatgtgaa agtgaaattt
     9301 tggattatct ttgctgttca gtccttttta ccaattctga ctttacttgg tctttctcta
     9361 tatctaggct tgcccatcat ttcgatgatt taccttattg tggcatggat ccttgccagt
     9421 gtcatccttt cttgtcacca ttattttaag gatgtgaaaa atctgtcaac caattggagt
     9481 agcattacgg acctggtgaa tcgttcaaat ggcatagtcg ccatagtttt attgtttatt
     9541 tatagtgcaa tcctgatggc ccttgtaatt gggagtatat tcttggttca gtctctctcc
     9601 cctatccttg ccatcagctt gggagtagga gctcttatcc tcctgcttgc tcttgctatt
     9661 tttggctatc attattacct gtcacgcata ttggcagaaa tagaaaaaag atgagctggt
     9721 tggtcgcttg cttgataaat tcagttcgac aaacgctttt atagtttgtt agaatgtagt
     9781 tgtaaatgat taagattggt aatcaaaaat atatagggag gaatgttttg aataagaaat
     9841 ataacatagt tctatttttg ttgtttatag tttatttatt gggatatttt tcaatttcaa
     9901 aaacgttaat tcctataatg tgtgtgatcc aagtattttt gatagaacat atatttagag
     9961 ttcgaaatag aatgatgcag ataggtgaaa ttataattat tgttgcttct ataatattat
    10021 ttattgatag tatattgagt ttgtaacaaa aggcttctct ataaaatcaa attttccaga
    10081 tacctattga agcagattta tttcttcatc tttcttctac tacctttgtc actaaatttg
    10141 acagacacat attgctgatt caacctctct acctataatc tcacagttaa cctgaggcta
    10201 gtttcatagt ttgctatttg attttcgttg ataaaaagaa atgctcctcc aagacggaag
    10261 agcatttttt attgtgattc ttacacattt acttcctagt tttgcaggaa gtctagtata
    10321 ccatttttta aaagaagagt aaaaaagcaa gggtagtttc ttttttgaga attgtctaaa
    10381 agtttgatat aatggtagtt atgaatagaa taagagtcag caaaagggtt gaaaagaagc
    10441 ttgctaaggg gctagtttta ctagaagcca gtgatcttga gaatgtcaat cttaaggatc
    10501 aggaagtaga ggtgcagggt caggaaggaa actttcttgg gactgcctac ctttctcagc
    10561 aaaacaaggg cttgggctgg tttgtcagca aagacaaggt ggccttcaat caaactttct
    10621 ttgaaacgtt gtttagaaaa gccaaagaaa agagaaacgc ctactatcaa gatgatttga
    10681 caactgcctt tcgtctcttt aatcaagagg gagatggctt tggaggtctg acagtggacc
    10741 tttatggcga ctacgccgtc ttttcttggt ataactctta tgtttatcag attcgtcaga
    10801 ctatatcaga agcctttaga caggttttcc ctgaggtttt aggagcttat gagaaaatcc
    10861 gctttaaggg tttggactat gaatctgccc atgtttatgg tcaagaagca cctgactttt
    10921 tcactgtttt agaaaatggt gtcctgtatc aagtctttat gaatgatggc ttgatgacag
    10981 gcattttcct agaccagcat gaggttcgcg gtagtttagt tgacggcttg gctatgggta
    11041 aatccttgct caatatgttt tcctacacag cggctttttc agtagctgcg gccatgggag
    11101 gagctagcca gacaacttct gttgatctag ccaaacgttc acgagaattg tctcaagcgc
    11161 attttcaggc aaatgggctc agcacagacg agcatcattt tatagtcatg gatgtctttg
    11221 agtatttcaa atatgccaaa cgcaaagact tgacctacga tgtgattgtc ctagatccgc
    11281 ctagctttgc tcggaataaa aaacaaactt tctctgtggc caaggattat cacaagttga
    11341 tttcccagag tcttgagatt ttaaatccgg gagggattat cattgccagt accaatgctg
    11401 ccaatgtttc ccgtcagaaa tttacagaac aaattgataa aggttttgca ggaagaagtt
    11461 accagatttt aaacaaatat ggtcttccag cagattttgc ctataataaa aaagatgaaa
    11521 gtagtaatta cctcaaggtg attagtatga aggttagtaa atgaaattaa tcgtttcagt
    11581 aatgccaaga agtttagagg aggctcaggc tctggatgac acgaggtacc tggatgccga
    11641 catcattgaa tggcgtgccg actatctgcc taaagaagcg attttgcagg tagctccagc
    11701 catttttgaa aaattcgcag gccgtgagtt ggttttcacg ctacgaactc gctccgaagg
    11761 tggagaaatc gacctttctc cagaagagta tatccatcta atcaaggaag ttgcgcaact
    11821 ctatcaacca gactatattg attttgagta ctatagctac aaggatgttt ttgaggaaat
    11881 gctggacttc ccaaatcttg ttttgagtta ccataatttc caagaaacac ctgagaacat
    11941 gatggaaatc ttgtcagagt tgacgatcct aaatccaaaa cttgttaagg ttgcggtgat
    12001 ggctcacacg gagcaggatg tcttagactt gatgaactat acacgaggct ttaaaaccct
    12061 caatcctgaa caggaatatg tgaccatttc tatgggtaag gtgggcaagg tctctcgtat
    12121 cactgcggat gtgactggtt cgagttggtc ttttgccagt ctggatgagg ttagtgcccc
    12181 tgggcagatt tctctagcta gcatgaaaaa aatcagggag attttggatg aagcttgatg
    12241 gctatacacg tttagctgca gttgttgcca atcctattaa gcattctatt tctcccttca
    12301 tccacaatag agcctttgag gcgacagata ccaacggtgc ttatgtggct tgggagattg
    12361 aagcgagtga cttggtagaa acagtggcca atattcgtcg ctaccagatg tttggcatca
    12421 atctgtccat gccctataag gagcaggtga ttccttattt ggataagctg agcgatgaag
    12481 cgcgcttgat tggtgcggtt aatacggttg tcaatgagaa tggcaattta attggatata
    12541 atacagatgg caagggattt tttaagtgct tgccttcttt tacaatttca ggtaaaaaga
    12601 tgaccctgct gggtgcaggt ggtgcggcta aatcaatctt ggcacaggct attttggatg
    12661 gcgtcagtca gatttcggtc tttgttcgtt ccgtttctat ggaaaaaaca agaccttacc
    12721 tagacaagtt acaggagcag acaggtttta aagtggattt gtgtgcttta gaatatgttt
    12781 ctgaactgca agcaaggatt gccgagtcgg atttgctagt taatgccacc agtgtgggca
    12841 tggatggcca atcctctcct gttcctgaaa acatagtctt accagaaact cttttagttg
    12901 cagatatcat ataccaaccc tttgaaacac cgtttttgaa atgggctaga agtcagggca
    12961 atccagcagt caatggtctg ggaatgttac tctatcaagc tgcagaagct tttcaactgt
    13021 ggacaggcaa ggaaatgccg acagaagaga tttggcagtc tttaacagaa aaataccaat
    13081 aaagaaaggg aaactctcct atgaaaatca gaatcgatat tcctcatcat ccttatgata
    13141 ttcagattga aaaaggttgt atggcccagg ctggtcagtg gttgcgagaa ctctggcaac
    13201 cgcaaaaggt agtcattgtg acagataacc atgtagcctc tctctatgca gagaaggtca
    13261 agctcagcct agaagatgct ggttttcagg tagctgtttt tgatttctta gaaggtgaag
    13321 aaagaaagaa tttaactact gttcagaaag tctatgaatt tctagtcaag caaggtctga
    13381 ctcgtagcga tggaatcgtt gctcttggtg gtggcgttgt tggggacctg gctggatttg
    13441 tagcctctac ctatatgcgg ggtattcact ttgttcagat tccgactagt ttgacagctc
    13501 aggttgattc ttctatcggt ggaaagacag gcgttaacac accatttgct aaaaatatgg
    13561 tggggacctt tgcccaacca gatggggttc tgattgatcc acttgttctt gaaaccctcg
    13621 gaaaaagaga gttgattgaa gggatgggtg aagttatcaa gtatggcttg attgaggatc
    13681 cagaactgtg ggctctcttg acgggactga atggttctgt tgagagtatt ttggaacatg
    13741 cagagacctt gattgaacat tcttgtcagg tgaagcgcaa gatggtggtt gaagatgagt
    13801 tggacaatgg tattcgtctt tacctcaatt ttggccacac tattggccat gccatcgaag
    13861 cgactgccgg ttatggcaag gtcatgcatg gagaggctgt tgccatggga atggtacaga
    13921 tttccaaggt tgctgaggaa aaaggcctca tgccagctgg cattacccaa tctatcacag
    13981 agatgtgtca gaaattcggc ttgcctgttg actatgaaaa ttgggaagtt gacaagcttt
    14041 atcaggctct tactcatgac aagaaagcgc gtggtaacac cttgaaattg gtcttggtgc
    14101 cagagcttgg ttcagcgatc attcacccag tttctctgga agagatgaaa gactacttgg
    14161 taaaataagg agagtgtatg agatatttaa ctgcaggaga atcacacggc ccccgtctaa
    14221 cagctattat tgagggaatt ccagctggac ttccattgac agctgaggat atcaatgagg
    14281 accttagacg ccgtcagggt ggctacggtc gtggtggtcg tatgaagatt gagagtgacc
    14341 aggttgtctt tacttcgggc gttcgccacg ggaagacgac aggggcgcct attactatgg
    14401 atgtcatcaa taaggaccac cagaaatggc tggacatcat gtctgcggag gacattgaag
    14461 accgccttaa aagcaagcgg aaaattactc atcctcgccc aggtcatgcc gatttggttg
    14521 gggggattaa gtaccgtttt gatgatttgc gaaattcttt ggagcgttca tcagctcgtg
    14581 aaaccaccat gcgggtggca gttggtgcag tagccaaacg cctcttggct gagctggata
    14641 tggagattgc caaccatgtc gtggtctttg gtggcaagga aatcgatgtt cctgaaaatc
    14701 tgacagtcgc tgaaattaag caaagagctg cccagtctga agtttctatt gttaaccaag
    14761 aacgagaaca ggaaatcaag gactatattg accaaatcaa acgtgatggt gataccatcg
    14821 gtggggttgt ggagacagtc gtcggaggcg ttccagttgg tcttggttcc tatgtccaat
    14881 gggatagaaa attggatgca agattggctc aagctgttgt ctctatcaat gcctttaaag
    14941 gggtggaatt tggtcttggc tttgaggctg gttatcgtaa aggcagccaa gttatggatg
    15001 aaattctctg gtctaaagaa gacggttata ctcgccgtac caataatcta ggtggttttg
    15061 aaggtggtat gactaatggg caacccatcg ttgttcgtgg ggtcatgaaa cccattccta
    15121 ctctttataa acctcttatg agtgtggata tcgaaaccca cgaaccttac aaggcaaccg
    15181 tggagagaag tgatccgact gctcttccag ctgcaggaat ggtcatggaa gcagttgtag
    15241 caacggttct ggcgcaagaa atcctcgaaa aattctcatc agataatctt gaggaactaa
    15301 aagaagcggt agccaaacac cgagactata caaagaacta ttaaggagtt cctatggcaa
    15361 aaacaatcta tatcgcaggt cttgggttga ttggagcctc tatggcactt ggtatcaaac
    15421 gcgatcatcc agattatgaa attttaggtt ataatcgtag tcaagcttcg agagatatcg
    15481 ccttgaaaga aggcatgatt gaccgtgcaa cggatgattt tgctagtttt gctcctttgg
    15541 cagatgtcat tatcctcagc ttgccaatca aacaaactat tgctttcatt aaggagttgg
    15601 ccaatttgga tttgcgagaa ggcgttatta tttcagatgc tggttcgacc aagtcaacca
    15661 ttgtggatgc ggcggagcag tatttggctg gcaagtctgt tcgctttgtc ggggcccatc
    15721 ccatggctgg tagtcacaag acaggggctg cttcggcaga tgtcaatctt tttgaaaatg
    15781 cctattatat ctttacacct tcaagcctga caagtcagga cacgcttaag gaaatgaagg
    15841 atctgctttc aggtcttcat gctcgtttta tcgagattga tgccaaggag catgatcgtg
    15901 tcacttctca gattagccat tttcctcata ttttggcttc tagtctcatg gagcagactg
    15961 cggtctatgc tcaagagcat gagatggcaa ggcgctttgc ggcaggtggt tttcgagata
    16021 tgacccgaat tgcggaaagc gagccaggaa tgtggacctc cattctcttg tccaatagcg
    16081 agaccattct ggatagaatt gaggatttca aggaacgttt ggaagtgatt ggtcaggcca
    16141 ttagtaaggg agatgaagag caaatttgga acttttttaa ccaagcgcgt gaacaacgcc
    16201 agaccatgga aatccataag cgtggtggtg tggatagctc ttacgacctc tatgttgacg
    16261 ttcctgatga agaagatgtc atcctgcgga ttttggaact gctacgtggg acttccttgg
    16321 ttaacatcca catcaacgag gaaaatcgtg aggatattca cggaatccta caaatttcat
    16381 ttaaaaatgc tcaagacttg gaaagagctg agcatctcat aacagaaaat accgactata
    16441 cagtcgtcat caaataagga gaagaacatg tcaaatattt acgatagtgc aaacgaactc
    16501 agtcgcggtc tacgcggatt accagaatac aaggctgtta aagcagctaa agatgcgatt
    16561 gcagcagatg ctgaggcaag caaaatcttt acagaatatc ttgcctttca agaggaaatt
    16621 caaaaactag cacatacagg tcaaatgcca gatgcgtcct tccaagctaa gatggaaggc
    16681 tttggtaaac agattcaagg aaatagcctc ttgtcagaat tctttaccaa gcaacaacaa
    16741 ttggccattt acctttctga cattgaaaaa attgtttttg aaccagtttc agaattgctg
    16801 aaataagaaa agaacgatcc taaagtcagg aatttttaag gaatttctgg ctttttatga
    16861 taaaataggt aaaagtattg caagtatgag gtccagtatg aaactaaaaa caaacattcg
    16921 ccatttacat ggtagtatcc gcgtcccagg tgacaagtct atcagccacc gttccattat
    16981 ctttggaagt ttggctgagg gtgagaccaa ggtttatgat attctgcgag gtgaagacgt
    17041 tctttcgacc atgcaggttt ttcgtgacct tggtgttgaa attgaggata aagatggggt
    17101 tattaccatt caaggtgtag gcatggctgg cttaaaagcg ccacaaaatg cccttaatat
    17161 gggaaattct ggcacctcga ttcgcctgat ttcaggtgtc cttgctggtg cagatttcga
    17221 agtagagatg cttggagatg atagtctttc caaacgtcct atggaccgtg tgacccttcc
    17281 actgaaaaaa atgggcgtca gcatttcagg gcaaactgaa cgagacttgc ctccccttcg
    17341 cttaaaaggg acgaaaaacc taagacctat tcattatgag ttgccaattg cctctgccca
    17401 agtcaagtca gccttgatgt ttgcagcctt acaagctaag ggggagtcag ttattatcga
    17461 aaaagagtgc acccgtaatc atactgaaga tatgttgaaa caatttggtg gtcatttaag
    17521 tgtggacggt aagaaaatca cagtccaagg gccacaaaaa ttgacaggac agaaggtggt
    17581 cgtaccagga gatatttcca gtgcagcctt ttggttagtc gcaggtttga ttgttccaaa
    17641 ttctcgtcta gtgctgcaga atgtggggat caacgaaact cgcaccggta ttattgatgt
    17701 cattcgtgcc atgggtggaa aattggaaat aactgaaatc gatccagtcg ctaaatcttc
    17761 taccttgact gttgagtctt ctgacttgaa aggaacagag attggtggcg ctttgattcc
    17821 acgattgatt gatgaattgc ccattattgc cctgcttgcg actcaagccc aaggtgtaac
    17881 agttatcaag gatgctgagg agctcaaggt caaggaaaca gaccgtattc aggttgtggc
    17941 agacgcctta aatagtatgg gagcagatat tactcctacg gcagatggga tgattatcaa
    18001 agggaaatca gctcttcacg gtgctagagt caatacgttt ggtgaccacc gtatcggcat
    18061 gatgacagct atcgcagccc tcttggttgc agatggagag gtggagcttg accgtgcaga
    18121 agccatcaat accagctatc ctagtttctt tgatgatttg gagagcttga ttcatggcta
    18181 aggtgttatt agggtttatg ggggctggaa aatcgactat tgcaagaggc ttggacccta
    18241 attaccttga tatggatgct ctgattgaga agcgcctagg tatgtccatt gcgaattttt
    18301 tcgctgaaaa gggagaagca gcctttcgtc aggtagaatc agaagtccta gctgatttac
    18361 tacaaacaga ccaagtcgtg tcaactggag gaggagtggt tatttctcag agaaatcgtg
    18421 acttactcaa gactaataca gataacatct acctgaaagc agattttgaa accctctacc
    18481 aacgtatcgc agctgataag gacaatcagc gaccgctttt tctaaataat agcaaggaag
    18541 aactagtagc tatttttcaa gaaagacagg cttggtatga ggaagtggct agtcgggttt
    18601 tggatgtgac caagctaagc ccagaggaaa ttatagagga actaagatga aaattgctta
    18661 tctaggtccc aagggatcat tttcacacca cgttgtgcag atagcttttc ctcatgagga
    18721 attgcaggct tttgctaaca ttacagatgt catcaaggct tatgagcaag gattagtgga
    18781 ctattctgtg gtgccagttg aaaattctat tgagggtagt gttcatgaaa ccttggacta
    18841 tctttttcat caggctcaca tccaagcagt agcagaaatc gttcagccta ttcatcagca
    18901 gttgatggtg gttccaggcc atactaagat tgaaaagatt ttttcacatc cacaggcctt
    18961 ggctcaagga aagaaattca tcgatgaaca atatccagag gctcaaatcg aggtaacagc
    19021 tagtacagct tatgcggccc gttttatttc cgaacatcca gaccagccct ttgcagcagt
    19081 tgcacctaga agttctgctg aagaatatgg attggaactg attgccgagg atattcagga
    19141 aatggaagcc aatttcacac gtttctgggt tctaggagct gaaaagccta gtattccctt
    19201 gcaagcacaa actgaaaaga tgagtttggc cttgacatta cctgacaacc ttccaggtgc
    19261 actttataag gccctgtcga cctttgcttg gcgaggaatt gacttgacaa aaattgaaag
    19321 tcgtccactc aagacagcac tgggtgaata ctttttcatt atcgatgtgg attataccga
    19381 taaggacttg gtccactttg cccaaaaaga attagaagcg attggaatcc agtataaaat
    19441 tctgggtgcc tatcctattt atccaatatc agaccatgga aaggagagaa gatgagtaaa
    19501 gaaaatccct taagtcatca tgagcagttg cgttatgatt atttgctaaa aaatattcac
    19561 tatctcaatg agagagaaaa aaatgagttt gcctatttgc aagaaaagct aactcttgct
    19621 aggggaaata gtagctctag cttggaacaa gaaagagaag agcaggttga cttaccaagc
    19681 tatgcgaacc ggagtcgctc acaatccaaa tcacaagcac tctctttccc tccaaaaaag
    19741 aaaagacgga agctccgtct taaacgaatt tttatggtga ttttttcact tttggtctgt
    19801 gtggctttgg ccatggtatt catgtttttg cgtggttacc aagatgctag cgcaaagaaa
    19861 actgctgatg cccgggcagc tcaagtagaa gtctttaatg gtcaggacac tagagatgga
    19921 gttaatattt taatcatggg tactgatggt cgaatcggcc agaacagtgt tgagacacga
    19981 actgactcta ttatggtatt aaatgtcggg ggctcagata agaaaatgaa gctagtcagt
    20041 ttcatgcgtg ataatttggt ctatatagat ggttatagtc aagtgattaa cggtagaaaa
    20101 cagacagata acaagttaaa cgtagcctac gagttaggag aacaagaggg gcaaaaaggg
    20161 gcagaaatgg ttcgccaagt cttgaaagat aattttgact tggacattaa gtactacgcc
    20221 ttggttgatt tccaggcctt tgccacagcg attgacacgc ttttccctga tggggtgacg
    20281 attgatgctc aattttcaac attgaatggg cgtcccctaa cagaagctac agtcggagat
    20341 gatttatacg ctaccgagac tgagtctcca acccaaacca ttaaagtcgg aaaacagcag
    20401 atgaatggct cgaccctgct caattatgct cgtttccgtg atgatgatga ggcggattac
    20461 ggccgtacaa aaagacagca acaagtttta acagcaattt tagagcaaat taaagatccc
    20521 actaaacttt tcactggttc tgaagctctt ggaaaggttt ttgctatgac ctcaaccaac
    20581 gtaccctata ctttcctcct aacaaacggt ttatctgttt tggatggagc aaaaaatggt
    20641 attgaaaaat tgacgattcc agaactgggt gactgggtag atgcctatga tgtttatgga
    20701 ggcttgggct tgctggttga tcaaaacaaa tatcaaacca agctcgctca aatgggcttg
    20761 agataagata atactcaatg aaaatcaaag tgcaaactag gaagctagcc gcaggctgct
    20821 aaaaacacag ttttgaggtt gtagataaga ctgacgaagt cagttaccta tacctacggc
    20881 aaggtgaagc tgacgtggtt tgaagagatt ttcgaagagt ataagacaga aaaatcaaag
    20941 tttgatagct atttggatag cagtcaggct ttgatttttt acagtctgca atagattttc
    21001 accccttgtt tgtggtataa tgaaacgata cgatagaaag aataatgaac aatatgactg
    21061 atttaaaagc aattcaggct cgtagtctgg agatggctga atattttgtg gccttttgta
    21121 aagaacatga tttgctctgt tatctctgtg gcggaggcgc tattggtgcc cttcgaaaca
    21181 agggatttat tccttgggac gacgacctag acttttttat gcctcgtaaa gattatgaga
    21241 aattagcaga attatggcct cgttatgcag atgaacgtta tttcttgtca aagagtcaca
    21301 aggattttgt tgatcgtaat ctttttatta ccattcgtga caaggaaacc acctgtatca
    21361 agccttatca gcaggatttg gatttgccac atggtctggc cttggatgtt ttgcctttgg
    21421 attattatcc gaaaaatcca gctgagcgga aaaaacaggt tcgttgggcc ttgatttatt
    21481 cactcttttg tgcgcaaact attccagaaa agcatggtgc tctcatgaaa tggggaagtc
    21541 gcattttact gggtttgact ccaaaatctc tccgttatcg catctggaaa aaagctgaga
    21601 aagaaatgac taagtatgat ttggctgatt gtgatggcat tacagaatta tgctcaggtc
    21661 ctggctacat gagaaacaag tacccaatca cgtcttttga agacaatctt ttcttgccat
    21721 ttgaaggaac agagatgcct attccaatcg gctatgatgt ctatctcaga actgcttttg
    21781 gggattatat gacgcctcca ccagcagaca agaaggtacc gcatcatgat gctgtcatcg
    21841 ctgatatgga taagtcttat acagaataca agggagaata tggtggctaa gaaaaaaatc
    21901 ttatttttta tgtggtcttt ttctcttgga ggtggtgcag agaagattct atcaaccatt
    21961 gtttcaaatc tggatccaga aaagtatgat attgatattc ttgaaatgga gcactttgac
    22021 aagggatatg aatctgttcc aaagcatgta cgcattttaa aatcccttca agattatcgc
    22081 caaaccagat ggttacgagc ttttttgtgg agaatgagaa tttattttcc aagactgact
    22141 cgtcgtttgc ttgtaaaaga tgattatgat gttgaagttt cttttaccat tatgaatcca
    22201 ccactgttgt tctctaaaag aagagaagtc aagaagatat cttggattca tggaagtatt
    22261 gaagaacttc ttaaggatag ctctaaaaga gaatcacata gaagccagtt ggatgctgcg
    22321 aatacaattg tagggatttc aaaaaagacc agcaattcta tcaaggaagt ttatccagat
    22381 tatgcttcta aattacagac aatctacaat ggatatgatt ttcagactat tctagaaaaa
    22441 tctcaagaga agatcgatat cgagattgct cctcaaagta tctgtactat cggacggatt
    22501 gaggaaaata agggttctga ccgtgtagtg gaagtgatac gattattaca ccaagaggga
    22561 aaaaactatc atctctattt tatcggggct ggtgatatgg aagaggaact gaaaaaacga
    22621 gtcaaagagt atgagattga ggactatgta catttccttg gttatcaaaa aaatccttat
    22681 cagtatttat ctcagacgaa agttctcttg tctatgtcta aacaagaagg ctttcctgga
    22741 gtgtatgtgg aggccttgag tctgggactc ccttttatct ctacggacgt tggaggggct
    22801 gaggaattat cccaagaagg acgatttgga caaatcattg agagcaatca agaggcagct
    22861 caggcgatta ctaattacat gacttctgcc tcaaacttta atgtcgatga ggctagccaa
    22921 ttcattcaac aatttacaat tacaaaacaa atcgaacaag tagaaaaact attagaggag
    22981 tagcatggaa actgcattaa ttagtgtgat tgtgccagtc tataatgtgg cgcagtacct
    23041 agaaaaatcg atagcttcca ttcagaagca gacctatcaa aatctggaaa ttattcttgt
    23101 tgatgatggt gcaacagatg aaagtggtcg cttgtgtgat tcaatcgctg aacaagatga
    23161 cagggtgtca gtgcttcata aaaagaacga aggattgtcg caagcacgaa atgatgggat
    23221 gaagcaggct cacggggatt atctgatttt tattgactca gatgattata tccatccaga
    23281 aatgattcag agcttatatg agcaattagt tcaagaagat gcggatgttt caagctgtgg
    23341 tgtcatgaat gtctatgcta atgatgaaag cccacagtca gccaatcagg atgactattt
    23401 tgtctgtgat tctcaaacat ttctaaagga atacctcata ggtgaaaaaa tacctgggac
    23461 gatttgcaat aagctaatca agagacaaat tgcaactgcc ctatcctttc ctaaggggtt
    23521 gatttacgaa gatgcctatt accattttga tttaatcaag ttggccaaga agtatgtggt
    23581 taatactaaa ccctattatt actatttcca tagaggggat agtattacga ccaaacccta
    23641 tgcaaagaag gatttagcct atattgatat ctaccaaaag ttttataatg aagttgtgaa
    23701 aaactatcct gacttgaaag aggtcgcttt tttcagattg gcctatgctc acttctttat
    23761 tctggataag atgttgctag atgatcagta taaacagttt gaagcctatt ctcagattca
    23821 tcgtttttta aaaggctatg cttttgctat ttctaggaat ccaattttcc gtaaggggag
    23881 aagaattagt gctttggccc tattcataaa tatttcctta taccgattct tattactgaa
    23941 aaatattgaa aaatctaaaa aattacatta gaacgggggt gaccaagtga ttgatgggaa
    24001 acgattatta tttagtttga ccatagtcag ttataccttg acgctagtaa gtggaattgt
    24061 gtatctgttt aataataata atgttagctt actttctact ttattgttct tgttggttag
    24121 tagcttaatt gcttgttgga atgatatcaa gtattactta atccatttta ttttctattt
    24181 aaccattttt gtatttctgg tatcaagacc gaccattgat tattttaggg atggtgcttt
    24241 ggatacctat catccaatag cctatcgttt tgcctttata gttgtcatgg tttcgattct
    24301 gggcttgacc acaggaggcg tcctggctcg ttacttcata gctaggaaga aaataaaagt
    24361 agcaaatata ggaaattctc taaaagaggt ttatatcaag cggttacgct ttgtatcact
    24421 aggagttttt cttctaacct atcctttcta tttcattcgg ttatttgaac ggctcttgta
    24481 tcgtttgcag acttcctact atgcctacta tgcaaatttt gaaagtaaac tgccttattt
    24541 tacctacatt ttgtctacct ttacggtcta tgcaatgtgt atgtatctgg caaccaagcc
    24601 aaagaaattg caggccacag cagtgcttgt ctcctttatt gcagctaata ctattcattt
    24661 ggcaattggg acacgaaatc cctttatttt aagtatttta tttgcttttg tttattactt
    24721 tatgcgggag caaactgaaa aaggaaaatg gattgggttt aaagaaaagt tagcgatttt
    24781 tgtaggttct cctattctca tgttagcgat gggagtactt aattatgtac gggataatgt
    24841 ccaagtttcc catacaggtt tctgggatat cttacttgac tttatctata aacaaggaac
    24901 tagttttggt gttctggctc gaggttttct atttaacagt agcctccctt accgagattt
    24961 ccgtaatttt acttttggtc ctgttcttga ttattttgca agggggagtt tgggagccat
    25021 tttcggagga aaagcctttg aacatacaac caatagtgtg gaactagcta ttgatagtaa
    25081 tagttatgcc cacaatctat cctatcttgt cttgaacaag gaatacttga aagggcatgg
    25141 tatcggaagt agttatatca tggagttgta taccgactat ggtatgattg gagtctttct
    25201 gcttagtttc ttactcggcg tattatttat agccatgctg caagtagcct atcgctcaag
    25261 gacaatccta tttgctttat ccctactcat cttgaataat ctattcttta tgccaagaag
    25321 cagcttttca gaaagtttct tcaatttatt tacaatgcaa ttctggggaa ttgttcttgt
    25381 gattatattt gtagcaaaaa tgcttacaaa ggaaaactag tatctactaa acaaaggaga
    25441 aaaaaatcat gtttgaacat tattcagtag ctgatttgtt tgcaaatctt tataaaaagc
    25501 gaaaagcaaa tattttagct ctcatcgctt tatttgctct cattgctgta ccatttacaa
    25561 ttaaagcagt taggaataaa aacactgtca aagatacaac aagttattca acttatctta
    25621 tctataaaat cactcctcca aaagagtcgg ccaaaacgat tttgaatcat caaattggtg
    25681 gttatagtga tttttatggg aaattgattg atggtaattt gaatggagct tatcttttca
    25741 atgatgtaga acccagtgag ttgaaaaaaa ttgccagtga attagacacg acagaaacaa
    25801 ccttgaaaaa ttcaacgaat gactattggt ggaaaaaatt gaccgtctac tatatgattg
    25861 acgatgcagg ggttggtgtg aaaattttga catcaagtaa agatgccaat gacttgttag
    25921 agaaaaaaat tgatgggttg atcgagaaat ttaaacatgc ctatgcaaat gtgaaaattg
    25981 aaaaactgga aaccatcaac tctaaagaat tgaacgcaaa tggtgaaaca gcgcttggct
    26041 taaatgtgaa aaatctgatt cttcgtttag ttgttattgg agtggtttgt gtgattttgg
    26101 ttgtgatggg aaatgtgtta gtttatctct ttaatccaac aatcaataga gtaggtgatt
    26161 tttctcagta tcaaattgat tttgtaacag agattacaac aattgctaac ctagcagatg
    26221 ttttgtcata caaaaatact ggacaggaat tgaccatcgt tagctcaaat aaagctatcc
    26281 tagataaatt gaaacagagt caagaagctt taaaaggaat gcattttgta gatttacagg
    26341 atgtatcatc tcttttggaa agagatacag tccttcttgt tgaagagtac ggagtgactc
    26401 gttataagaa atttgagcaa agtcttcaaa ttctcagaaa cttaaatcgt tctatcctcg
    26461 gtgtagcaac ctttaaatta taagtattct gatgtataag gtcttcaaaa tcggctaaga
    26521 gccgattttg aaggcttttt ctatctgtct gcagaaattt tcttttggag tctcctatag
    26581 aaagacccta gggaaaatct atccgtatag aggagccttc ttttgataaa atcgtaaaaa
    26641 tctagtataa tagatagaac tgaaagtatg aggttactag caatgaaaat gaaacaaatt
    26701 agtgatacaa ctttaaaaat cacgatgtct ttagaggatt tgatggatcg tggaatggag
    26761 attgctgact ttctcgttcc tcaagaaaaa acagaagagt tcttttatgc tatcttggat
    26821 gagctagaga tgcctgatag ctttctggat acaggcatgt tgagcttccg tgtgactcca
    26881 aaacctgata aggtagatgt ctttgtgacc aagtcaaaga ttgaccaaaa tctagatttt
    26941 gaagacttat cggatttgcc agatatggaa gaattggctc aaatgtctcc agatgaattt
    27001 atcaaaaccc tggaaaaaag catagcagac aaaaccaagg atgatatcga agccattcaa
    27061 tctcttgagc aagttgaagc caaggaagaa gagcaagagc aggctgaaca agaagctgag
    27121 agtaagaaag aaccttacat ctactacatc ctttcttttg ctaagttggc tgacttggta
    27181 gcttttgcca agacagtgac ttttgaaatg gaaacttctg aactctacaa aatgaacgag
    27241 cgctattatt tgaccatttt agtggatatt gaaaatcatc caagcccata tccagcttgg
    27301 ctgttggccc gtatgcgcga gtttgcagac gatagtgata tcagtcgctc agtcttacaa
    27361 gagtatggtc aagtcttgat gagtcacgat gcagtgctca atctgcaaaa aatcggctaa
    27421 tcctttctgg aaagctattt tcagatttta agaagagcga atcgtctgat tcgttttttc
    27481 tttttatact gaaatagtga tttactataa taggaatttt cacaaaattc tgttataatg
    27541 gctatattag aaaatttcga ggagataaag atgacagtta aaattgcttt actaggattt
    27601 ggtaccgttg caagtggtgt gcctttcctc ctaaaggaaa atggaggaaa aattaatcaa
    27661 tcagcacatt cagatatcaa agttgctaag gtattggtca aggatgaaga tgaaaaaaat
    27721 cgcttgcttg cagcagggaa tgactttaac tttgtaacca atgtggatga tattttatca
    27781 gaccaggata ttactatcgt agtggaattg atggggcgta ttgagcctgc taaaaccttt
    27841 atcactcgtg ccttggaagc tggaaaacac gttgttactg ctaacaagga ccttttagct
    27901 gtccatggcg cagaattgct agaaatcgct caagctaaca aggtagcact ttactacgaa
    27961 gcagcagttg ctggtgggat tccaattctt cgtactttag caaattcctt ggcttctgat
    28021 aaaattacgc gcgtgcttgg agtagtcaac ggaacttcca acttcatggt gaccaagatg
    28081 gtggaagaag gctggtctta cgatgatgct cttgcggaag cacaacgtct aggatttgca
    28141 gaaagcgatc cgacgaatga cgtagatggg attgatgcag cctacaagat ggttattttg
    28201 agccaatttg cctttggcat gaagattgcc tttgatgatg tagcccacaa gggaatccgc
    28261 aatatcacac cagaagacgt agctgtagct caagagcttg gttacgtagt gaaattggtt
    28321 ggttctattg aggaaacttc ttcaggtatt gctgcagaag tgactccaac cttcctacct
    28381 aaagcgcacc cacttgctag tgtgaatggc gtaatgaacg ctgtctttgt agaatctatc
    28441 ggtattggtg agtctatgta ctacggacca ggtgctggtc aaaaaccaac tgcaacaagt
    28501 gttgtagctg atattgtccg tatcgttcgt cgtttgaatg atggtactat tggcaaagac
    28561 ttcaacgaat atagccgtga cttggtcttg gcaaatcctg aagatgtcaa agcaaactac
    28621 tatttctcaa tcttggctct agactcaaaa ggtcaggtct tgaagttggc tgaaatcttc
    28681 aatgctcaag atatttcctt taagcaaatc cttcaagatg gcaaagaggg tgacaaggcg
    28741 cgtgtcgtta tcatcacaca caagattaat aaagcccagc ttgaaaatgt ctcagctgaa
    28801 ttgaagaagg tttcagaatt cgacctcttg aataccttca aggtgctagg agaataagat
    28861 gaagattatt gtacctgcaa ccagtgccaa tatcgggcca ggttttgact cggtcggtgt
    28921 agctgtaacc aagtatcttc aaattgaggt ctgcgaagaa cgagatgagt ggctgattga
    28981 acaccagatt ggcaaatgga ttccacatga tgagcgtaat ctcttgctca aaatcgcttt
    29041 gcaaattgta ccagacttgc aaccaagacg cttgaaaatg accagtgatg tccctttggc
    29101 gcgcggtttg ggttcttcca gctcggttat cgttgctggg attgaactag ccaaccaact
    29161 gggtcaactc aacttatcag accatgaaaa attgcagtta gcgaccaaga ttgaagggca
    29221 tcctgacaat gtggctccag ccatttatgg taatctcgtt attgcaagtt ctgttgaagg
    29281 gcaagtctct gctatcgtag cagactttcc agagtgtgat tttctagctt acattccaaa
    29341 ctatgaatta cgtactcgcg acagccgtag tgtcttgcct aaaaaattgt cttataagga
    29401 agctgttgct gcaagttcta tcgccaatgt agcggttgct gccttgttgg caggagacat
    29461 ggtgaccgct gggcaagcaa tcgagggaga cctcttccat gagcgctatc gtcaggactt
    29521 ggtaagagaa tttgcgatga ttaagcaagt gaccaaagaa aatggggcct atgcaaccta
    29581 cctttctggt gctgggccga cagttatggt tctggcttct catgacaaga tgccaacaat
    29641 taaggcagaa ttggaaaagc aacctttcaa aggaaaactg catgacttga gagttgatac
    29701 ccaaggtgtc cgtgtagaag caaaataaag aatagaagat aggatgggga aactcttgac
    29761 cagagggttt catatccttt ttgtgaaaag aagtttatac tcaatgaaaa tcaaagagca
    29821 aactaggaag ctagccgcag gctgctcaaa acagtgtttt gaggttgt
//
LOCUS       DAVBNN010000022        27949 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBNN010000022 DAVBNN010000000
VERSION     DAVBNN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.022"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ847_001038"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ847_001038"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3050389.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ847_001039"
     CDS             complement(1995..2927)
                     /locus_tag="VQ847_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3050390.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ847_001040"
     CDS             complement(2924..3781)
                     /locus_tag="VQ847_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3050391.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ847_001041"
     CDS             complement(3785..5131)
                     /locus_tag="VQ847_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3050392.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ847_001042"
     CDS             complement(5144..5428)
                     /locus_tag="VQ847_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3050393.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ847_001043"
     CDS             complement(5432..7462)
                     /locus_tag="VQ847_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3050394.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ847_001044"
     CDS             7653..8660
                     /locus_tag="VQ847_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3050395.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ847_001045"
     CDS             8663..8863
                     /locus_tag="VQ847_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3050396.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ847_001046"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ847_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3050397.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ847_001047"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ847_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3050398.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ847_001048"
     CDS             complement(9784..11664)
                     /locus_tag="VQ847_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3050399.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ847_001049"
     CDS             complement(11658..12527)
                     /locus_tag="VQ847_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3050400.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ847_001050"
     CDS             complement(12611..15256)
                     /locus_tag="VQ847_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3050401.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ847_001051"
     CDS             complement(15347..16627)
                     /locus_tag="VQ847_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3050402.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ847_001052"
     CDS             16798..18882
                     /locus_tag="VQ847_001052"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3050403.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ847_001053"
     CDS             complement(18922..20601)
                     /locus_tag="VQ847_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3050404.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ847_001054"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ847_001054"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3050405.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ847_001055"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ847_001055"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3050406.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ847_001056"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ847_001056"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3050407.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ847_001057"
     CDS             24983..26494
                     /locus_tag="VQ847_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3050408.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ847_001058"
     CDS             26516..27847
                     /locus_tag="VQ847_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3050409.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         8235 a         6218 c         5365 g         8131 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaatt
//
LOCUS       DAVBNN010000023        27332 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBNN010000023 DAVBNN010000000
VERSION     DAVBNN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.023"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(1..362)
                     /locus_tag="VQ847_001059"
                     /pseudo
     CDS             complement(1..362)
                     /locus_tag="VQ847_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(438..1214)
                     /locus_tag="VQ847_001060"
                     /pseudo
     CDS             complement(438..1214)
                     /locus_tag="VQ847_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1138..1332)
                     /locus_tag="VQ847_001061"
     CDS             complement(1138..1332)
                     /locus_tag="VQ847_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050410.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1502..1852)
                     /gene="tnpB"
                     /locus_tag="VQ847_001062"
                     /pseudo
     CDS             complement(1502..1852)
                     /gene="tnpB"
                     /locus_tag="VQ847_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1833..2018)
                     /locus_tag="VQ847_001063"
     CDS             complement(1833..2018)
                     /locus_tag="VQ847_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050411.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2322..3884)
                     /gene="guaA"
                     /locus_tag="VQ847_001064"
     CDS             complement(2322..3884)
                     /gene="guaA"
                     /locus_tag="VQ847_001064"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3050412.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4026..4724
                     /locus_tag="VQ847_001065"
     CDS             4026..4724
                     /locus_tag="VQ847_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3050413.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4767..5663)
                     /locus_tag="VQ847_001066"
     CDS             complement(4767..5663)
                     /locus_tag="VQ847_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3050414.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5672..6607)
                     /locus_tag="VQ847_001067"
     CDS             complement(5672..6607)
                     /locus_tag="VQ847_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3050415.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6604..7329)
                     /locus_tag="VQ847_001068"
     CDS             complement(6604..7329)
                     /locus_tag="VQ847_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3050416.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7413..8048)
                     /locus_tag="VQ847_001069"
     CDS             complement(7413..8048)
                     /locus_tag="VQ847_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3050417.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8050..8877)
                     /locus_tag="VQ847_001070"
     CDS             complement(8050..8877)
                     /locus_tag="VQ847_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3050418.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8899..9234)
                     /locus_tag="VQ847_001071"
     CDS             complement(8899..9234)
                     /locus_tag="VQ847_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3050419.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9235..9766)
                     /locus_tag="VQ847_001072"
                     /pseudo
     CDS             complement(9235..9766)
                     /locus_tag="VQ847_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10397..11008
                     /locus_tag="VQ847_001073"
     CDS             10397..11008
                     /locus_tag="VQ847_001073"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3050420.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11053..11781
                     /gene="rlmB"
                     /locus_tag="VQ847_001074"
     CDS             11053..11781
                     /gene="rlmB"
                     /locus_tag="VQ847_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3050421.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11820..12731)
                     /gene="trxB"
                     /locus_tag="VQ847_001075"
     CDS             complement(11820..12731)
                     /gene="trxB"
                     /locus_tag="VQ847_001075"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3050422.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12797..13021)
                     /locus_tag="VQ847_001076"
     CDS             complement(12797..13021)
                     /locus_tag="VQ847_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3050423.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13099..13842)
                     /locus_tag="VQ847_001077"
     CDS             complement(13099..13842)
                     /locus_tag="VQ847_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3050424.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13842..14642)
                     /locus_tag="VQ847_001078"
     CDS             complement(13842..14642)
                     /locus_tag="VQ847_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3050425.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14800..15156)
                     /locus_tag="VQ847_001079"
     CDS             complement(14800..15156)
                     /locus_tag="VQ847_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3050426.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15169..15681)
                     /locus_tag="VQ847_001080"
     CDS             complement(15169..15681)
                     /locus_tag="VQ847_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3050427.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15681..16175)
                     /locus_tag="VQ847_001081"
     CDS             complement(15681..16175)
                     /locus_tag="VQ847_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050428.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16310..16756
                     /locus_tag="VQ847_001082"
     CDS             16310..16756
                     /locus_tag="VQ847_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3050429.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16753..17400
                     /locus_tag="VQ847_001083"
     CDS             16753..17400
                     /locus_tag="VQ847_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3050430.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17421..18002)
                     /gene="pdxT"
                     /locus_tag="VQ847_001084"
     CDS             complement(17421..18002)
                     /gene="pdxT"
                     /locus_tag="VQ847_001084"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3050431.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18003..18878)
                     /gene="pdxS"
                     /locus_tag="VQ847_001085"
     CDS             complement(18003..18878)
                     /gene="pdxS"
                     /locus_tag="VQ847_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3050432.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19030..20409)
                     /locus_tag="VQ847_001086"
     CDS             complement(19030..20409)
                     /locus_tag="VQ847_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3050433.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20703..21626
                     /locus_tag="VQ847_001087"
     CDS             20703..21626
                     /locus_tag="VQ847_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3050434.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21686..22291
                     /locus_tag="VQ847_001088"
     CDS             21686..22291
                     /locus_tag="VQ847_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3050435.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22310..23554
                     /locus_tag="VQ847_001089"
     CDS             22310..23554
                     /locus_tag="VQ847_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3050436.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23777..24034)
                     /locus_tag="VQ847_001090"
     CDS             complement(23777..24034)
                     /locus_tag="VQ847_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3050437.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24076..26112)
                     /locus_tag="VQ847_001091"
     CDS             complement(24076..26112)
                     /locus_tag="VQ847_001091"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3050438.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26372..27289)
                     /gene="glyQ"
                     /locus_tag="VQ847_001092"
     CDS             complement(26372..27289)
                     /gene="glyQ"
                     /locus_tag="VQ847_001092"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3050439.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         8058 a         6130 c         4986 g         8158 t
ORIGIN      
        1 tattggaaag gaccagatgt ccgtctttta aaatggtctt aaaggtttct ttatacttga
       61 ggctgtattc aattgccctt cctagttttg aacctgctaa aactgactga cggcggcacc
      121 aagcaaagaa gtcttccatt aggggctgga cgtttctgta gtcgttcatc agctggcaaa
      181 gcctcccagt ctctttccaa ggcaaataac tggtcacgat aggctaaacc tttagctcct
      241 aaggatgatt tatctgcttg cttgggggtc gcttcaaaaa atttccttct cacatgcgcc
      301 caacatccaa caagttcagc ttcttccagt tgacgataag cttctagcgg ttcgcagttt
      361 accaagctta gcgtcgcctt gctcctaaac cttagactgc tatcgcatag gcagaactag
      421 aggactaaag ttctaagtta ctgccgcaac atatcacaat gcatatagcc agaataattt
      481 cctaggaatt cttgcactac cgaaccactc cgacgctgat catggtggta cagcgtaatc
      541 ccttgtttct cagctttccc agacaaaaaa gtccaatagt aagtcagctg actatcactt
      601 tctaagaccc gataagaggt ttcatctgca tgaagaagag cttgttctaa caacttttct
      661 cgtaaaaggt tataaaggga ctctaaatag tattgactcg ccttgatatg ccaattagca
      721 atttccttac gtgtgattgg taaacccatc ttagcccaat cttcttctta gcgataattg
      781 ggtaccttca gaataaactt ctgatggatg gtgtgagcga taatagaagc tgagccaagg
      841 ctatgcgcca aaggggcttt aggaatagga gctttcacga ttttatcact tggattattc
      901 ttactgcatg tttggcattt gtaagcgtgt tggatatgat tcactctttt taattgcgca
      961 agaataaaga ccaattcttg tcgttgaagg ctcgctccaa tctcttttag ctctccctga
     1021 cagtcagggc aaatgcagtt ctctaagcga tgatgaactt cttctgaatc aaattgggca
     1081 agaatagctt gacgtttccc tttagctttc ttacgtttat aggtgatttc ttctctttca
     1141 actgggtaag tcagagtctt cttccatatt ttgttcctct tcaaaaagac tgagttgtcc
     1201 agatgggcaa acacttttct cagaggattt tccatagagc ttttgcgtta gataagccac
     1261 ttgttcacga agaagggcaa gttcattggt gagactatca attgtagcac tctgttgttg
     1321 aatgattttc aatcttctcc catagacttt cctccttatt tcctaacttt attatatagt
     1381 gtattgaatc tataacagta caccttgact gctaaaatat ttctataaat taatttgact
     1441 ttcctgatag agatgttcat atcttatttc aattcactat actaaaaaga aagtcctcat
     1501 ttcaatagaa atcacgactt tctgatgaat ttatttttgg agtgatagaa aagcccttca
     1561 taagccagtc tacttgttca ggtgtgagag ctttgacatc cttttctgta ctgggtcaag
     1621 tcagtctgcc gttctcaaag cgtttatata gtagccaaaa tccttgacca tcccagtaaa
     1681 gggctttaaa gcggtcttta cgtccaccac aaaagagaaa aacttgaccg gagaaaggat
     1741 ctaattcaaa gtgggtttta accagataag ccagtgaatc aatgccttgc ctcatatccg
     1801 ttttcccaca tacgagatag acctgcccta ggctagatag atgaattgtc atagagcaac
     1861 accttatcca aaagctgttc taccatttcg agattgagag attgaaaaaa acttacttca
     1921 agcttgccaa tacgaatttt aagcagaata tcatttctct ttttagaatc aaaaggacga
     1981 gattgtggaa tctctacagg aacaataggt tgtggcatta aaatatcctc caatagtttt
     2041 actttactaa tagtatacag gaggagctcc atgaatgata gataccttgt tatgacgcgc
     2101 ttaccatatt agaaagttgg ctctctaatt aaattaattc tcattatata tatcaaaaga
     2161 ccgcagtttg aaaactacgg tctaattttt tgtccaaatg taaaccactt ggaactatta
     2221 ttcaatttat tctttttagc aaatgttccc gttttaatcc cagttacagt ttttaatcct
     2281 ttgtaaccgt tgattttaca aagcttttaa tttttttgcg attactccca ctcaactgtt
     2341 gcaggtggtt tacttgtaat atcgtagacg atacggttaa catgatccac ttcatttacg
     2401 atacgtactg agattttttg aagtacttcc catggaattt tggcaaaatc agcagtcata
     2461 ccatcgatag aagtgatagc acggattgca atcgtgtagt catacgtacg accgtcaccc
     2521 ataacaccga ctgaacgaac gcctgtgtta acagtgaagt attgccaaat atcgcggtca
     2581 agtccagctt tagcgatttc ttcacgaaga atagcgtctg attcacgaac ggtttcaagt
     2641 ttctcttcag tgatttcacc catgacacgg atagcaagtc ctggtcctgg gaatggttgg
     2701 cgccatacga tatggtctgg cataccaagc tctgtaccaa gagcacgaac ttcatccttg
     2761 taaagagtat tgagtggttc aatcaattca aactgcatat cttctggaag accacccacg
     2821 ttgtggtgtg acttgatagt ttgagctgta tccgtaccag actcgataac atctgtatat
     2881 aaagtacctt gagcaaggaa tttcacatct ttgagcttgc ttgcttcgtc atcgaataca
     2941 tagacaaact cgttaccgat gattttacgt ttttgttcag gatcagaaac gccagcaagt
     3001 ttgtcaagga aacgtttagc agcgtctgct ttgacgatat tcaaaccaaa cttaccaccg
     3061 agcatgtcca taacttgatc agcttcgcct ttacgaagaa gaccgtggtc cacgaagata
     3121 cagatcaatt gatcgccaat cgctttttgg agaagaaccc caacgacaga tgagtcaaca
     3181 ccacctgata gaccaagaag gacacgttta tcaccgacgg tttcacgaat ttttttgatc
     3241 tgcatgtcaa tgaaattatc cattgaccag tcacctttag ccttacaaat gttaagggca
     3301 aagttacgaa ggatatcatt tccgtataca gaatgacgaa cttctgggtg gaattggata
     3361 ccgtaaatgt gtttatctgg gttttcgatg gctgcgtatg ggcagtcagc tgatgtacct
     3421 gtacgaacaa agtcagcagg aatctcagta accgcatcac catggctcat caaaacagtc
     3481 tgttcatcag gtgttgattc aaaaagcgct gatggtgtgt gagttagggt tgattgaccg
     3541 tattcacgat ttccagcatc acctgcagga acaacttttc ctccaagttt atgggtcaat
     3601 aactgcatac cataacagat tcccaaaatt ggaattccga gttcgaagat ttctgggtca
     3661 atatcaaatg aaccatcttc atatacagaa tttggaccac ctgatagaat aattcctaca
     3721 ggattgactt cacgaacttc agcagctgaa attttatggc tttttagttc tgaaaaaaca
     3781 ccaatatcac ggatacggcg tgaaatcagc tggttgtact ggctaccata gtccaatacg
     3841 atgatttttt ctacatcttg caaatcagtt gaaatgttgc tcatcttttt cctttctcaa
     3901 aagaaatatc ttttctcaat attctatcac aaataagggc gaattaccaa ctaaacaagg
     3961 cgaagtttga ctttttctag tttattgggg tacaatagag aaaagataga aatgaagtga
     4021 aaaatatgct acctgcttat atgaaaatcc atgatcagat aaaaaaggat attgacgagc
     4081 accgttgggc tattggtgag aggcttccca gtgaaagaga tttagctgag cagtttgcgg
     4141 tcagtcgcat gaccctccgc caagccgtat ctctattagt cgaagaaggc gtcttagagc
     4201 gccatgtagg aagcggcacc tttgtttcca gtactcgagt acaagaaaag atgcgaggga
     4261 caaccagttt tactgaaatt gtcaaatccc aaggtaaagt tccctctagc cagctcattt
     4321 cctacaaaaa aaccattccc aatgagcaag aagttgccaa gctaggaatt tttccaacgg
     4381 acaatattat ccgaatggag cgggtccgct atgccgacca agttccccta gtttatgaag
     4441 ttgcttctat tcctgaaaaa ttcattaagg actttaaaaa agaagaaatc accagtcatt
     4501 tcttccaaac cttgcaaaaa catggctatc gtatcggcaa atctcaacag accatctatg
     4561 ctcgccttgc taaagaaaag attgcccact atttggaagt tgaaaaagga catgctattc
     4621 ttggattgac ccaggtttcc tacctagaag atggtactgc ttttgaatac gtaaaaagtc
     4681 aatatgtagg cgaacgcttt gaattttatc ttgaaaataa ttagattacc acgcaaaaac
     4741 tctctgtcac ggacaaagag tcttttttat ttttctaaga ataaatcttt caaagaaatc
     4801 aaagttacag caaacaatat cattgccata ccaagaaaat caatgggata aaattgttca
     4861 ttcattatta agaaggcaaa gaaaatcgcc gatattggct caattgaagc caacaagctt
     4921 gacttgaccg gtcctatcag actggctcct ttaaggaaag ctgtataggc aaagacagtc
     4981 ccgataagga taatgcctgc aaacgcaagg agaaaatcaa gactagtcgg gatatcggcc
     5041 tgtagaaccc ctgtaaaagg aagagcgacc aaacctgcta tgaccattcc cacaccaatg
     5101 accaagctgc tcccccactt tttaatcaag gctatgggta aaatgatata cagagcataa
     5161 gtaaaggcag aaaagagacc ccagaacaga ccagcaggtg tcatggataa ctggtccaac
     5221 tgcccatgtg ttgcgatcag gaaggttcct ccgatggcga atatgatgga aactatctct
     5281 cccagtgtcg gtgccaccct atccttgata cagctataaa ttaaaattcc gacaggacaa
     5341 acatactgaa gcaccgtcgc tgttcccgca ttggtctcct gaatagcaga cagataggcg
     5401 aattggttga gaaaaagacc aatcagagca aaaataagaa gagacagcaa actctttcta
     5461 tcctttaaaa agaccagtat tttatccttt gcagtagcat aagccaagag catgagaatt
     5521 ccaccagcga ttaaaagacg caagttggtc aagaccagag ccgaaattcc gtgtgccatt
     5581 aggtattggc cactcgttcc tgacaacccc caagcaatac cagccacaac tgttagtaaa
     5641 gtccctttta aactatttga catgtctctc cttactcttc tttgcgaatc aagttcatca
     5701 cttgattgcg gtctaatatc cattgagctc tctcgtcctt ttcataggta cgattcgata
     5761 ggaaaatagt ggcttcttgc ttctgacgat tccacatgat aaaggtacct gtatagcccg
     5821 tatggtctag ccaatctcct tccaaattcc atgctaaaga acgttccttg tcatccaaag
     5881 gagaaaaatt ttgacttaag tctcttgcaa aatcatctgc taaatagtgt tctaaaaaga
     5941 tttgtaaatc ctttatagtc gaaaataaac cagcactccc agcatgtcta cccaggagac
     6001 gagccttggg atcatgcact atgcctgcct ctacacctct aactgttgga acagcaagct
     6061 caactgaccc aaacttggtt tccgtcattc cccaaggttt ccagacttga tcctttaaaa
     6121 tcacatccaa atcttgatta aaaattcttt ccaaaataaa gcccaacagc aaaaaatgga
     6181 catccgaata aagaaaggct ggctgacttc gtctgttgag atgaaacatc gcttccttta
     6241 attcaggggc tgttaaaaga tcacgattag gaataaaagg atcaaggtct gttgcatgag
     6301 tcaagagctg gcgaatagtg atgtctggat aatcactctc aggtaaaaaa tctattacca
     6361 gtctatcaat atctaattga cctatttccc acaagaaggt acaaactgtg ccaaccccaa
     6421 caaccttgct gacactagct aggtcataaa ctagtcctgc ctcagtctgc aagccatgct
     6481 ctgggtcact ctggcctaaa tagaactctg tccattgatt gtccttaaaa tacgcaaaag
     6541 aggctccggg ataaattcct gcctcgattt gttcttctat ttttttaata atcttggtcc
     6601 acttcatact tcttcaaacc acaattcaac attatttcta tctttacaaa ggaagaattt
     6661 ttcagactta ggaataaaat attcagtaga ctcaaacttc tggcgaagac ttgctatgtc
     6721 taattcattg accaagaact tgagcataga taagtcccag gtaaccgtat tgtccacagt
     6781 caaatcctgc ccctgagctg gaataaaatc aagggatgcc ccaatttcag atgattccaa
     6841 gaaactttcg atatcagttg ggagatgtaa ttccatagaa atctcaaatt tacttaaaga
     6901 aattgatacc aaatctgttt gaaattcagg cttttctcct acttctacta gacttgctct
     6961 gtcatcttcc gcatgaatca aaatcaaatc atcttctggt gagaaaattt caaaagcgta
     7021 gccattttga cctttatata atcgatgaat cgaatctgtt ttagataaga ttccttcaat
     7081 ttctaaggga ttttccacct tgacaatcaa tctagctagt ttttttcttc cctctacctt
     7141 acgagtacgc atactgggag cttcttctaa aaccagcttt tcaagacccg tttggtcacc
     7201 tagtgacaga aaggccgatt cttctaacaa ggccttcatt ccaagggttt caatataaaa
     7261 tgtttcattt aattttctat tattagcttt taaagtagga ataatccgta caatctgatt
     7321 tacattcata aattcctccg tcacttttta ttttaaagga ttttagaatt ttttacaaga
     7381 tattatgctc aaatttaaca ttatttagct atttagtaaa gatagtcttt caaggctttt
     7441 gacaaagcct gataaccagc aatactgagg tgcagtccat cagttgtata ttcttttttg
     7501 agttggcctg cttggtctgt caaacaatca aatactggca caaattccac ctgcatatag
     7561 gcagatgcaa gctcttgata ggcttgattc cagttctgaa ttttttcatt cgagcggata
     7621 tagactgcct gctggtactc ctctccctca ttgacaggca aaatggaaag caatttaatc
     7681 tctgtcaatg gataatcgcg agcaacggat tgaatgatag cttcgagatt attgagagcc
     7741 tcattcacag gaacatcctt tccgatatca tttgtcccaa tcagaagaaa aattttatct
     7801 actgctccac catatagatg agcatcaagg ttctctagta acagtcctgt ctgatagcca
     7861 cgaattcctc gattgacaat cgtctttgaa gtcccaaata gctcctgtag aggataatac
     7921 tcgacaatgg aatccccaat aaaaagaatg tttggttcta caacagaaat gtgatttagg
     7981 tgacgatact tagtttgaat tttttcttgt tcctttagga gccaattttc taataactgt
     8041 actgccactt cattctcctt tttctaacca gttttccaag acttgataaa ctcctccttg
     8101 gctgttggct ggtgctagag cagtcgccac agctttggct ttctcatcag cattttccat
     8161 cgcataggca attccagcca tttcaagcat ttcaacatca ttttcactat caccaaaagc
     8221 catgatttct tgggatttca agtcccagcg cttgagtaat tcctccaagc cccatgcttt
     8281 atgaatccca gcttggagga tatcaatgca accatagcca ctggatacag ctcggacacg
     8341 gccatcaaag agagcattga tttcttccaa aaccgaactc aaacgttcct caccaacaac
     8401 catgctcatc ttgagcacac caccaaagag gtcagatgtt aattcatcca caaattgcat
     8461 ccgttggtag aatttttcaa tcatttctgg agtcataaaa ctttcaagat ctgtaaaaat
     8521 cgtaccttcc ttgacaaaat cacccttcat ccccgttaca acaaactggt cctgacacgc
     8581 tcgacccttg aaatgagtca aagccttgtt gacaatggcg tcatcccatg tctgagcctg
     8641 aatcaattca ttgttttcaa aaatacgagc gccattagca acaaccagaa ccactcgatc
     8701 caccaaggga ctcagtagtt gtctcatgcg gtgaatttca ttgcccgtcg caatgacaaa
     8761 acgaatgccc ctttgatcca actgatctaa aatcttttcc aatcgtggga gatcaagctg
     8821 acctctagca tccagcaagg tcccatccat atctgtcgca attaccttaa tcatcattta
     8881 ctttcctctg gattcaagct aataccactt caatcccaca tgttcattca tttctttata
     8941 ggctgtatca attcgttcct tagtcgcttc atctaactgg tcacgatgac tgccatcctc
     9001 tataaaatct tccaaaatat aagtttggta atgatacaag ggatatcctt ctggtgaaaa
     9061 ggttcccttt ggtgttcgat tgacccaagt aggatgagct ttagctgttc cgatagttgt
     9121 ttttccatcc ttcttcttga tggtgacatc catgagaaca ccacgttcag tccacttagc
     9181 attctcttca tctcccatag attcaatccg ttgattggaa atgaagttcc ccatttaata
     9241 gacaatgagc ttcttatctc catctttttc caccgtttca gatggttcaa caacgtgagg
     9301 atgccctcca aagataatat ccgctcccca atcgatcatc ttgtgataaa gagctttttg
     9361 ttcttcagtt ggttccaatc gatactcaac acccatctga agcatgataa tggtgatatc
     9421 tgcttccttc tctgcccgtt caatttcaac cttcatctta tcttcgttta aatctgaaag
     9481 ataacgatta tagtcttcct gagaaatata ctgctcaatt ccattgaaac cataggaata
     9541 ggctaacaat gcaaccttga taccattcac ttccttaatg accagcggag cctgaacacg
     9601 tggttcgtgc gtataaactc cgattggagt gattccagct ttctcaataa tatcggccgt
     9661 tgaaataact ccctcaagtt gaaataactc cctcaagttg cgaatccaaa atatgattat
     9721 gagctaaatc cagcacatga taacctgcct ccttaatagc atccataact tcagcaggag
     9781 cattaaagag aagataaccc gctaaataat gatccttatt aatggttcct tcaaaatcac
     9841 caatagctaa atctgcttgc ttgagccaag gagtcacata ctcaaaattt tcatgaaagt
     9901 cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc
     9961 cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt tgcttagtcc
    10021 cctcttgaga aatagtatct cgtttttgac tagtcaaggg attccttgga agctttcaaa
    10081 caacaagacc aagcccttca taaaacgaaa agctaaacca ccctgatttc gattttatct
    10141 tctttgtatc ttcattctcc ctactttctt atgcaagcct tttcttttta ttatatcaca
    10201 gataagtatt tctttcacaa ttgaattgaa cttcccatct attttctata aatcctaaat
    10261 gccataatgc tttcaattct tgtcattttg tgatatcatg tagaggaaat gaactaatcc
    10321 acagtggctt atttcaagta taccacttgg gctttggcag tagctaactg cactaaatat
    10381 aatataagga gagaaaatgt ctgcaataga acgtattaca aaagctgctc acttaattga
    10441 tatgaacgat attatccgtg aagggaatcc tactctacgc gcgattgctg aggaagtcac
    10501 tttcccccta tctgaccagg aaatcatcct aggcgaaaag atgatgcaat tccttaaaca
    10561 ttcccaagac cctgtcatgg ctgaaaaaat gggactccgc ggtggtgttg gactggctgc
    10621 tccccagtta gatatctcaa aacgcattat cgctgttttg gtacctaata ttgttgaaga
    10681 aggcgaaact ccacaggaag cctacgattt ggaagccatt atgtacaatc caaaaatcgt
    10741 ctctcactct gttcaagatg ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg
    10801 taacgtgcct ggctatgttg ttcgccatgc ccgcgttact gttgactact ttgacaaaga
    10861 tggagaaaaa caccgtatca aactcaaagg ctacaactcc attgttgttc agcatgaaat
    10921 tgaccacatt aacggtatca tgttttacga tcgcatcaat gaaaaagacc catttgcagt
    10981 taaagatggt ttactgattc ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt
    11041 tataatagag gcatgaaaac aaatgatatt gtctatggcg tccacgccgt taccgaagcc
    11101 ctccttgcaa atacaggaaa caaactctac ctccaagaag atctccgagg taagaatgtt
    11161 gagaaagtca aggaactagc tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa
    11221 tctctctctg agattactga aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa
    11281 tttgcctata gcgagctaga ttacatcctt gcaaaaacac gccaagaaga aaatccactt
    11341 ctattgattc tagatggtct aaccgatccc cataatctgg gttctatctt gcgaacagcc
    11401 gatgcgacca atgtttcagg tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct
    11461 gtcgttgcca aaacagccac aggtgctatt gaacacgttc caattgcccg agtgacaaac
    11521 ctcagtcaaa ccttagataa actcaaggat gaaggcttct ggacctttgg aacggatatg
    11581 aacggtactc cttgccacaa gtggaataca aaagggaaaa tcgccctcat catcggaaat
    11641 gaaggaaaag gcatctctag caacatcaaa aaacaggtcg atgaaatgat taccattccg
    11701 atgaatggac atgttcaaag cctcaatgcc agtgttgctg cggccattct catgtacgaa
    11761 gtttttctaa atagactata aaaaagtttc cagtcatctg attggaaact tttttataat
    11821 taactatgtt ctgtgataaa cttgtaggct tcttgaccag cgatagctcc atctccaact
    11881 gctgttgtta cttggcgaag gtctttcaag cgaacatctc caactgcaaa gataccgtcg
    11941 actgcagtct tcatgtggct atctgtcaca atccagcctg cctgatcttg gatattcaat
    12001 tctttaacaa aatcgctaag agggtccaaa ccaacataga taaagacacc accgaaggct
    12061 tgctctgtca cttgacctgt tttcacattt tcaaaaacga cagattctac tctgttttca
    12121 cccttgattt ccttcactac agaatcccag ataaagctga ttttttcatt cgcaaaggcg
    12181 cgatcttgta aaaccttttg ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc
    12241 ttagcaaaac gagtcaagaa gagggcttct tcaacagctg aatctccacc accaactacc
    12301 aataaatctt ggtcacggaa gaaagcacca tcacacacag cacagtaaga aacaccacga
    12361 ctgttcagtt cttcttctcc aggcactccc aaaggacggt gtttagaacc agttgctacg
    12421 ataactgtac gtgtttcata tgtttggtca tcagtcatca ctttcttaaa atcaccatgg
    12481 tcttcgacat tttcaacata accataaatg tgctcaacac caagattttc aagtggttca
    12541 aacatctttt cagccaattc aggtccacta atattagcgt atcctgggta attttcgata
    12601 tcagatgtat tattcatctg accacctggc agaccacctt caatcaaagc tacttttaga
    12661 ttgcttcgag cagcatacaa ggccgcagtc atccctgcag gtccagcacc gataataata
    12721 gtatcgtaca tatagattcc ttctttcttg ttgtaactat ctttattcta actctttctt
    12781 gtcaatcacg caaggattat gccttgaaaa caagaattaa actcataacc gcaaaggata
    12841 atactgggac aaccaagact ccaatcataa tcatatcata gagatgggct tggcgagccc
    12901 tggctgtctt atcaactccc gacatggctc tcagaccaat ccaaatccct aaaaaaatca
    12961 gaacaaggat ggtggtcaag atcaaactct cgaaatataa agaaaatagt tgcagtagca
    13021 tgatttctct catttctatc ttttttaaag agtaaactca gctagtccaa ctaactgagt
    13081 tttcctttat ctattatatc aaatataagt ccgtttgtaa ctagcgaaga attcttttgt
    13141 ccgctcttct ttaggggtgt ggataatctc atccggagtt ccagactcga tgattttccc
    13201 cttatctaag aagagaattt tatccgcaac ttgggctaca aaggacatgt catgactgac
    13261 caaaatcatg gtctgacctg acttagcagc atctgcaata gacttttcta cttcaccgac
    13321 caattctggg tcaagggctg aagttggttc gtctaagagc aaaacatctg gtttcatagc
    13381 aagcgcacgc gctagggcaa cccgttgctt ctgtccacct gataaatggc gaggataatg
    13441 gttttcacgg tccgaaagcc caaccttagc caactcttcc ttggcaatct tagtcgcttc
    13501 ttggtcagat aatttcttga caacaaccaa gccttctttc acattatcaa gtgctgttcg
    13561 acgttcaaat aaattaaact gttggaaaac catagacaac ttacggcgta gggcaaggat
    13621 ttcttcttga gtgattttag aaaaatcaac tgaaaaacca tcaatctgaa tagagccact
    13681 gtcaggtgtt tcaagataat tgagactgcg aagaaaggtt gattttccag ctcctgaaga
    13741 accaatcaag gctacaactt cccctttttg aatatccaag ttcagatgat ccaagacagt
    13801 ctgtcctgaa aaggatttgc ttaaattcga aatcttaatc attaacgaag gtctcctttc
    13861 acatctgttt gcactgtatc aggtgcagaa atagccattt ttctctcgat gaaacgaccg
    13921 aggctttcaa ttccgatatt gactacccaa taaacaaggg caacagagat gaagcgttca
    13981 aaatagcgat aatcagctcc acctagaatc tgagcttggg caaagacttc cacaacaccc
    14041 gcactaaaag ctagagatgt tcccttggtc aaaccgatga gggaattaat caaggttgga
    14101 gtagctacca ccgctgcatt aggaataatc actcgtcgat aaacttgcgc tcgggtcata
    14161 cccagactgc gcgccgcctc aatctcacca ggattaactg agagaatggc tgcacgaatg
    14221 gtttcactag cataagctgc ctcattaaag gcaaaagcga caatcgcaaa agctgcagct
    14281 ggaatcgcat tgatattgag accagttccc cattgctgat tgagggcttt caaagccaaa
    14341 ggaattccgt agtaggtcaa catgagttgc accaaaatcg gtgtcccttt taagaaacta
    14401 acaaagaagg cctgcaaggg atataaaatc ttgacacgat tgatcttcac aatggcaaaa
    14461 agaagcgcca aaaccaagcc aaaaagggca ccaccaattg tcaacataat tgttgttgga
    14521 agttgttgga caattctagg gattccatca aagaccgaac gtaggctaaa cagcttgcca
    14581 tccggaatca attgcatcaa gttttggtac caatctgatg ctaaaatcgt tgtaacattc
    14641 ataaaaacat cctcttctga taatgattca ttctaccatg cttctgccgt caatgaaatt
    14701 atttgctacg gtcagataca gactttgtct acctactagt ttatcatact ttgaaacagg
    14761 gaagttatat attttatcta tcaaagagat agataaaaac tatttcagtc ccagttcttc
    14821 ataagatttt cgataaccga tttgcttaac agttccattt tctactaaaa tgggccgttt
    14881 taacaacata ccgtcacttg ctagcaactc agccgcttct tggtttgaca aacttcctac
    14941 cttatctttt agccctaatt cacggtattt gataccactg gtgttgaaaa attgcttcaa
    15001 ttcaaatcct gaggtttcta gccaattcaa aatgacttct tggctaggtg tttcttccac
    15061 gatatggacg gctttatagt ccacacctaa ttgatttaat tcttgttttg cttttttaca
    15121 agttgaacat ttggggtatt cgataaattc taacatgtgc ttctccttct atttgtttat
    15181 atctttaaaa tctacgcctt catgctccaa gagccaagct ttcttttcca ctcctgcagc
    15241 atagcctgtc agacgcttgc ctgctcccaa cacacgatga caaggtacta ggatagacca
    15301 aggattgcgt cccactgctc caccaattgc ttgagcagaa gccacttgca ggtcttgagc
    15361 aatttgtcca taggtcactg tctgaccata aggaatgccc tgtaaatagt cccaaactct
    15421 cttttcaaaa ttcgttccga ttggcgccaa gagcaagttg gataaatcct gaggcttgcc
    15481 tttaaagtaa tcatctaagc aagcaataac tgggtctaaa ataggatgac taacaacttc
    15541 ttctatcgtt tcatctccta gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc
    15601 atacaaataa tggtcatcag ctacaagtga tagaatacca attggtgagg agtagaggat
    15661 ttttacatac ttcttttgca ttatttcttt aatttttgat aggccaagcg ttcgccatct
    15721 actggcacct taccaacttg tttaaaacca agtttttcaa aaatatgttg cataaccttg
    15781 ttttcagcat gcgtatctga gcgaaaatca agataatcaa aaccttcaat caagccctct
    15841 aagaaggttt gagcaactcc ttttccctgc acatctgctg ccacagcaat acggtgaaag
    15901 actagatact ctgactctcc agcttgccag tttccctcat aaatagcttc ataggcctcc
    15961 tctggactct tggtcacagc agcataggct agcagttctc cctcttccaa ggctacgtag
    16021 gcttgccctg agatgatatc atcgataata acatctgcat ttggatagcc attttgccac
    16081 tggttactac cagcatctgc taaacatttt ttggcatcct ctatcacctg catgatggca
    16141 tctacttcat ttggaaaagc taaacgaatt tccatctttt ttcctcattt ctgactagtt
    16201 tctcccatca tagcataatt taagtctttc tacaagcagt taaaacttga ctttgtattt
    16261 ttgttatttt ataatctagt tatcaaaact atataaaaag gagttgaaaa tgaaaactac
    16321 cttttcctac ccaaaatggg cagaaattcc aaacattaac ctctatctgg accaggtttt
    16381 gctctatgtc aatcaggtct gcgcccctat ctctcctaat aaagacaaag gcctaacagc
    16441 atctatggtc aacaattatg tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata
    16501 ccaacgccaa cagattgccc gtttgattgc tatcacaacc ctcaagtctg tattttctat
    16561 tcaagaaata gcccagacac ttaatactct acaaactcaa gcaagttcag accaactcta
    16621 cgatgctttt gtggactaca tgaaccaagg aattgaccca gctaacccta ttatccaaac
    16681 cagctgccaa accgttaaac tctatcatca aactctagac ttaatcgatc atactcaaga
    16741 ggaggtaatc caatgaacac tagtcttaaa ctcagcaaac aactcagttt tggagaggag
    16801 attgctaata gcgtgaccca tgctgtgggt gcagtcatca tgcttatctt gctgcctatt
    16861 tcatccatct atagttatga agcacacgga tttttatcct ctatcggcgt ttccattttc
    16921 gtcatcagtc tctttctcat gttcctatca tccaccattt atcactctat ggcctatggt
    16981 tcgacccaca aatatgtttt gcgaatcatt gaccattcta tgatttacgt tgccattgcc
    17041 ggctcataca cgcccgttgt cttgaccttg atgaataact ggtttggcta tctgattatt
    17101 gtcatccaat ggggaacgac catctttggt attctctata aaatctttgc taaaaaggtc
    17161 aatgagaaat ttagccttgc tctttacctg attatgggct ggttggttct ggctatcatt
    17221 cctgccatta tcagtcaaac gacacccgtt ttctggagtc tcatggtaac tggcgggctc
    17281 tgttatacag ttggagctgg attttatgcc aagaaaaaac cttatttcca catgatttgg
    17341 catctcttta tcctagctgc gtccgcactt caatacatcg ctattgttta ttacatgtaa
    17401 aaaagttgag aaattcaatc tcaacttttt tctttacaca tattgataaa gtactggtgc
    17461 aagcgcacat catcagtcaa ttctggatga aaagaactta ccaacatatt tttttcttgg
    17521 gctgcaacaa tttgattgtt cactgttgct aaaatttcta caccctcacc aacactactg
    17581 ataatcggac cacggataaa ggtcattgga atcttgccaa ctcccttaca ttctgcttcc
    17641 gtgtagaaac ttcctaattg gcgcccataa gcattacgct cgaccaccat atccatagtt
    17701 cctagatgac tctctttctg agaagtgatt tccttagcca gcaaaattaa gcccgcacag
    17761 gtcccaaaca ctggtaagcc agatagaatg gcttctcgga tgggaagtag catgttctgg
    17821 tcacgtaaga gcttgcccat ggttgtagac tcaccaccag gcaaaatcaa acccgacaag
    17881 tcactctgat cttgctgaaa atcatctaga tttctgagtt ctacactctc gacacctaat
    17941 tgatctagca cttttgcatg ttctgcaaag gccccttgca aggccaatat tccgattttc
    18001 atctattttc ctcgttcagc catgagaatt tggatttcat tttcattaat accaaccatg
    18061 gcttctccta aatcttcaga gatttgagct aggatttgag gattacggaa gttagtcaca
    18121 gccttaacaa tggcactcgc tcgtttaaca ggatctcctg acttgaaaat acctgaaccg
    18181 acaaagaccc cctctgcccc taattgcatc attaacgcag catctgctgg cgttgcaaca
    18241 cctccagcag cgaaatttac aactggcaat tttccatgtt catgaacata ttggaccaat
    18301 tctacaggga cttgcaaatc cttggcagca acataaagct cgtcctcacg taagttttga
    18361 atgcggcgaa tttcctgatt catcatacgc atatgacgaa cagcttggac tatatcccct
    18421 gtccctggtt ctcctttggt acgaatcatg gaagcacctt cagcgatacg acgcaaggct
    18481 tcacccaaat ccttagcacc acagacaaaa ggaacttgga attctttctt gtccacatgg
    18541 aaacggtcat cagctggaga tagaacttca ctctcgtcga tataatcaat ttcaatagcc
    18601 tctaaaatct gagcttcaac aaaatgcccg attctgacct tagccattac tggaatacta
    18661 accgcttctt ggatttcctt aatcatcttt gggtcgctca tgcgggaaac tcctccagct
    18721 gcacgaatat cagccggaat tcgttccaag gccatcacag ctgccgcacc agcagcttct
    18781 gcgatacgag cctgttcagg attctgcaca tccataataa caccaccctt gagcatctgt
    18841 gccaagtttt tatttagttc ataacgattt tcagtcattt gttttatcct catcatttgt
    18901 attggtagct accttttcat tttaagtcag aacagaatga agcacaagat aaaaaaacta
    18961 taattgtatg gggacagatt agctaaaaac tatctgacct taacttaagg ccagatagct
    19021 cattcatttt tatttttcag ccgtaagggc agccattgtg atgtagttgt atggtttgtt
    19081 gaagtgtggc aagaagaaga ggtctgtcaa tgccaattta tcaattgtca catgctcttg
    19141 gatagcaagt gagaacatgt ggattcccat gctaattgca atatcatgtg aaaccatttg
    19201 ggcaccaaga atttcacggc tatctttgtc aaagacaatc ttaattgcta cttcatggtt
    19261 gtcatgtttc atgaattctg gtttttgaag atcgttaaag cctgtttcag ttgcgttgta
    19321 accagcagct ttcgcttttt caagagtcaa accagttgaa accatgtgaa gaccgtagat
    19381 tgagatacca tttgaacctt gaacaccgat tccttccaat tcatgtccac aagcattgta
    19441 ggcaccaacg ataccagtgc gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt
    19501 acgagcattg tcataaacag tcgcacagtc accaacagcg taaacgcctg ggatagatgt
    19561 ttcttgtttc ttgtctacaa ggaaggcacc gttgcggaag agttcgatct taccatctgc
    19621 aagggctgtg tttggacgga aaccaactgc aaggataacc atatccacgt caaagctttc
    19681 tttgtcagta atcaagcgtt caactttacc gtcaccttcg attgctttaa cagtttgacc
    19741 tagagccaag cggatgttgt gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt
    19801 gtcatagtaa ccgttcaaga cagtatcaac gatatcaaca aggacaactt cttttccaag
    19861 acgttcaaag gcttcagcaa gttcaacacc gatgtaacca ccaccaacaa cggcgatacg
    19921 gtcgaggtgt tggctcttgt cagaaagttt attgataact tcttcagcat tttggtacaa
    19981 tttcacgaat tgtacgtttt caagagttgc tttaaattcg cggtttcctt taacaatttc
    20041 aacaccttcg attggtggca agattggtgt agaacctgta gcgaaaatca atttttcgta
    20101 tgattctttg tgctcttttc cttcaacttc cgctgtaact actttgttat catagtcgat
    20161 tgaaagaaca ggtgagttca tgtaaacttt agcaccttta gcttccaatt tttctttatc
    20221 agaatagaac aagccttcag caccgtcaat ttgttcacca atccaaagag ccattccaca
    20281 tcctaggaaa gagatgttag agttttggtc aaatacaaca atttcgttct catttccaaa
    20341 attatccaac atggtattga tacatgctgt accagcgtgg ttagcaccga ctacaacgat
    20401 tttactcata aaaatttcct gccttcattc taaatttacc ttactagtat accatttacc
    20461 gttagcgttt acaagggggg tactattatt tcagcatttt ttatcaaaaa taattcccca
    20521 tttatcctgt tttcaagcct cataaatttt atgagcatat ttcttgactt tttccaaatt
    20581 ttgtttgtga aaattctaac tttatggtat tataataaca tgaaaatgaa atgtaagggc
    20641 ttcaatttag atgattattt gatattacaa cttattttct ataagagaaa ggagttggta
    20701 gcttgactct tcgttcacat tctgaacggc taatggggac tactatcact atttcattag
    20761 tggatgagca agccgatatc tttctccaaa aatcctttga cttgctcaaa gaacttgaat
    20821 accgcttcaa cgccaatagt caagaatctg agttgatgga aatcaattat caagcaggaa
    20881 tagcccccgt cacggttcat ccagacctgt ttgagctgat ttcacttggg ttagagcata
    20941 gcctagcgct ctctagccac ctcaatatca gcattggtcc cttaattcaa acctggcgta
    21001 tcggtttttc agatgccaag gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa
    21061 tcaatcctca tggtatcgag ttagattctt ctacttctac tgtgttttta aaacagaaag
    21121 gaatgaagat cgatctaggt tgtttagcca aaggatacag tgcggataag gttgcccaat
    21181 ttcttaggaa agagggggtg acttctgcct tgatcaatct gggagggaat atcctgacca
    21241 ttggaaaaaa tcaggcaaga ggggataacc catggcaaat cgggattcaa gacccagcca
    21301 atcctagggg aaatcattta atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag
    21361 gcatttatga acgtcacctg accgtcgatg gacaagatta ccatcacatt tttgacagtc
    21421 aaacaggata tcctgttgaa acggaactag cgagtctaac aatcatctct gataaatcag
    21481 tcgatggcga aatctggacg actcgactct ttggagaaag acctgcttct atcctctggc
    21541 aagtcgaaag tttggagggc atcgaagtca tcctcatcga taaagaaggc cacctaagct
    21601 gttcttcagg aattcctact ctatagagac aactgtttca atggaatttt aaaattgtat
    21661 tatgtaaaaa gagaaaggaa atctcatgtt aaaacttatt gctattgttg gaacaaattc
    21721 aaaacgttct acaaaccgtc aattgcttca atacatgcaa aaacactttt ctgacaaagc
    21781 tgaaattgag cttgttgaaa tcaaggccat tcctgtcttc aacaaaccag ctgacaagca
    21841 agtacctgct gaaatattgg aaattgctgc taaaatcgaa gaggcagatg gcgttattat
    21901 cggtactcct gagtatgatc actctattcc agctgttttg atgagcgctc ttgcttggtt
    21961 gtcttatggt atttacccac ttttgaacaa accaatcatg attacaggtg cttcttacgg
    22021 tacgcttggt tcatctcgtg cccaattgca acttcgtcaa atcttgaatg ctcctgaaat
    22081 caaggcaaat gttcttccag atgaattctt gctctcacac tctcttcaag catttaaccc
    22141 aagtggcgac ttggttgacc ttgatgttat caagaaattg gatgccatct ttgatgactt
    22201 ccgtatcttt gtaaaaatca cagaaaaatt acgtaatgca caagaattac ttcgcaaaga
    22261 tgctgaagac tttgactggg aaaatttgta agataggaga ccaaaaagaa tgaaatttgt
    22321 tggacttgtt ggatcaaact acgatcaatc atataaccgt aagctcttgg aatttatccg
    22381 tcgctacttc aaactcaaat ttgaattaga agttcttgaa attgacgaag ttccaatgtt
    22441 taaccaagat gaaaaatggg atgaaagttt ccaattacgt tatttatata acaaaattac
    22501 tcgtgcagat ggtgttatca ttgctactcc tgagcataac cacactatct cagcttcact
    22561 caaatctgta cttgaatggc tttcatacga agttcatcca tttgaaaaca agcctgttat
    22621 gattgtgggt gcatcatact atgaccaagg aacatcacgt gctcaagttc accttcgtaa
    22681 aatccttgat gctccaggtg ttaatgccta cacgcttcca ggtaacgaat tccttcttgg
    22741 taaagctaag gaagcttttg ataacaacgg aaatatcacc aacgaaggca ctgttaaatt
    22801 ccttgaaact tgcttagata actttgttaa atacgtagga gtcgtttcga aattgaaaaa
    22861 accaaaacca atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta caaccatcac
    22921 agaagttgac cctgacgatc cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt
    22981 ttctggtgat acctatgtca aattggacca cggtatccta acagttaacc aaattgatat
    23041 gttcttgaaa gctatgccat ttgaattgac atacgctgac gacaacaacc aattcctcta
    23101 ctacaacaac gctcaccaag atccagacac tatgttcgct aaacgtgtac cacctcaatc
    23161 aggtagccgt atgtcgactg ttcatggttc tcttccacca gcacgtatga agaacgtaga
    23221 gtgggttatc ggaacacttc gcaacggaaa ccaagaatac gtccgtacga tcgttccagg
    23281 ttctcctgca ggtgttatca acactcacaa ctaccaagca atgtactatc ctgatggatc
    23341 atacgctggt atcaatgaaa tcgtctttaa cttccaacca tggcttgact ggtacctaaa
    23401 agagactggt caacgtttgg tgggtggtag cggaccattt gctcctgctg ccggaggtca
    23461 tggagacgcc gatgctactt ctggcgcttc tgattcaggg gatgctggag gccacggtgg
    23521 tgacgcagac gctacagccg gtgcaagtta ctaatgatag tttttaggaa ccattatggt
    23581 tcctttttta gcgaaaaaag actagcaaac acaaactgct agtctctttg ttatcgtttc
    23641 atctatcttt gttaaaagaa agagtactta tactcaatga aaatcaaaga gcaaactagg
    23701 aagctagccg caggctgtac ttaagtacgg caaggtgaag ctgacgtggt ttgaatttga
    23761 ttttcgaaga gtattattat gaatttgggt catcaagact acggccatgt aatccttttt
    23821 cacgttgtac ttggcgtagt ttttctggtg taacatcgtt tccttcttcg tccacaattt
    23881 tgattccttc aatgtggtga cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta
    23941 gtttggcttg ttccactttt tcttctgatg ttaagccttc tgtttttttc tttttagcaa
    24001 gctcattgat acgagcaatt tttttcggat ccatttcttc tcctttgtaa taagataaag
    24061 tccgtttatc aaattttatt tagtgttaat ttggttaaaa caagcaaact tagctgcttt
    24121 cttggttagt tgtgacaaga ttgccaaacg attttgacgg acagcctgat cttcagccat
    24181 taccatagta ttttcaaaga aagcatcaat gactgggcta agcgcaaaga gttgtttcaa
    24241 ttgctgactt gcaggtcctg ataaaacgag tgtttctact gcttctgcca aagctttttc
    24301 ttggtcattc tcaaatagtg ctgaatcaac tgtagcaacc ccttctgcct tctcagccag
    24361 gttaaaggca cgagaaagtg attcaacaga tggtttaaaa tattcttcct tgcttacttc
    24421 tacgagagca cttgctgctt ccaacatatc tgccacaaca aagtttgaac ctgcaagaac
    24481 tgcttccttg atatcttttg gagtagagcc catcatctta tcaacacgag ccttgataaa
    24541 gtccataacc tctgctttat tttcataagt caaactgtca aatttcaatg cataaaggct
    24601 atcaatcagc tcatccatag caatgtgcca accaaaggca tccaagatac gaaccacacc
    24661 ttgagttgca cgacgaaggg cataagggtc attagaacct gatggaatca atcctactga
    24721 gaagaaactc aaaatcgtat ccaatttgtc tgcaatggct agaactgcgc cgaccttgct
    24781 ctctggaagt tctccttcag ctgatgtagg catgtagtgt tcacgaatag cagctgccac
    24841 cgctggagtt tcaccagcaa gaagggtgta tttttcaccc ataattcctt ggagttcgtc
    24901 aaattcacca accatacctg tcaataagtc aaacttgtaa atggctgctg cacgagcaag
    24961 gtcaactgtt tcatccactg acaaaccagc tttttctgcc aaaagtacag tgatttgacc
    25021 cgtacgaatc atgtgttcac gaagggaacc aatcttctca tggaaggtga cattgtttaa
    25081 tttttcaaca agatctgaaa tcaccaattt ttggtcttca cgccagaaga attctccgtc
    25141 ttccaagcgg gctaccaaga ctttttcatt tcctttaatg acatttttca aacgctctgc
    25201 gtttccgtta cgaacagaaa tgaagtttgg caagagtttt ccatcttgat cacgaacaac
    25261 aaagtaacgc tggtgttcct tcatagaagt caccaagact tcttctggaa cttcaaggta
    25321 tttagcatca aaacttccca tgaaggcagt tgggtattca accaaattca agacttcatt
    25381 cagcaaatcc gcatcaattt cgatacgtac accatgtttt gcctcaattt ccttgatttg
    25441 gtcaacaatc atttgctcac gttcacatgg atctgcgatt acaaactgct tacgaaggtc
    25501 ttcttcatag ctcaatgctg actgaatttt ggtttctttc cccaagaaac gatggccacg
    25561 gctcacacga cttcccttga tatcaaggaa atccaagtca aactcttgct catccaagag
    25621 aacagttaaa gtgtggacag gacgaatgta ttcaaagcta tttccagccc agtgcatgct
    25681 gacagggaaa gtcaatgact tcaagacatc tacaacacca ggaacaatgg cttcaactgc
    25741 ttgaccaact tcttccttag tgacatagac atattcttca cccttgattt cacggaattc
    25801 gatatcttca acagtcaagc cttttccacg gacaaatcct tgagctgctt tggtaaagtt
    25861 tccatcacta tccaaggcaa ttttctttgc tggtcccttg aaatcttctg tcaaatcaga
    25921 ctgtttgtct gataaaccag tcacacgaac agccaaacga cgtggtgttg agaaggtttg
    25981 aatggcttca aaagacaggc ggttttcctt gaggaaggct gccatttttt cgcctagttg
    26041 tttttcactt ggtgtgacaa cataggctgg taattcttca agaccgagtt ctactaataa
    26101 gttttttgtc atgttttttc ctttacattt tcttcaatct tttttgatat gcaccttagg
    26161 tactggggac gtcgctaact aactctgtga gtctgtatgg aaatccaatg ctaaatttat
    26221 caagatttcc aacaatctca tcaaagtgga tttagctgac tgatttttga acctaaggtt
    26281 tcaaaaatcc ccacataaca gtacggcggt gcatatccct ctagcaagtc ttcgacttgc
    26341 ctctaacgat tttagagtac agtattactc actattctgc gtcttctgct aaaagtttaa
    26401 ctcgtgtttc ttcatccaaa agtgggtaac ctaggcgttt gcgttctgca acaaaggttt
    26461 tggctacaac acgggccaag ttacggatac gagcgatata gcctgcacgc tctgttacag
    26521 atacggcacc acgcgcgtca agcagattaa aggtatgtga acatttgaga acatagtcat
    26581 aggcagggtg taccaagcct tcttctaatg cacgaccagc ttctttttca aacttatcaa
    26641 agttttcaag caaaatttct tggtccgaaa tttcaaatga atattttgag tgctcatact
    26701 caggctggat aaagatttct ccgtatttta caccatcagc ccactcgata tcatagacag
    26761 agtctacttc ttgaatgtaa gaagccaagc gctccaaacc ataggtaact tccgcagtca
    26821 cagggccagt tgccaatcca ccgacttgtt ggaaataagt gaactgagtg atttccattc
    26881 cgtcaagcca aacttcccaa ccaagaccag ctgaaccagt tgatgggttt tcccagttgt
    26941 cctcaacaaa acgaatatcg tgctccaaag gattgattcc caatttttcc aaagactcaa
    27001 ggtaaagttc ttggatattt gatggagaag gcttcatgac cacctggaat tggtggtgtt
    27061 ggtagagacg gttagggttt tccccataac gaccgtcagc aggacgacgt gatggctcta
    27121 cataagctgc attccatggc tcaggtccga tagcacgaag gaaagtgtaa ggactcattg
    27181 tccccgcacc tttttcattg tcataagcct gcataagcat acaaccttgg tcattccaaa
    27241 attgttgcaa agtcaaaata atttcttgaa atgttaattt cttagacatt gtttactcct
    27301 taataaaaaa tgatttcttg cgacacgagt ct
//
LOCUS       DAVBNN010000024        26827 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBNN010000024 DAVBNN010000000
VERSION     DAVBNN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.024"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            393..1571
                     /locus_tag="VQ847_001093"
     CDS             393..1571
                     /locus_tag="VQ847_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3050440.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1885..2016
                     /locus_tag="VQ847_001094"
     CDS             1885..2016
                     /locus_tag="VQ847_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3050441.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2037..3587
                     /gene="dltA"
                     /locus_tag="VQ847_001095"
     CDS             2037..3587
                     /gene="dltA"
                     /locus_tag="VQ847_001095"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3050442.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3584..4828
                     /gene="dltB"
                     /locus_tag="VQ847_001096"
     CDS             3584..4828
                     /gene="dltB"
                     /locus_tag="VQ847_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3050443.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4842..5081
                     /gene="dltC"
                     /locus_tag="VQ847_001097"
     CDS             4842..5081
                     /gene="dltC"
                     /locus_tag="VQ847_001097"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3050444.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5074..6342
                     /gene="dltD"
                     /locus_tag="VQ847_001098"
     CDS             5074..6342
                     /gene="dltD"
                     /locus_tag="VQ847_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3050445.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6497..6937
                     /gene="adcR"
                     /locus_tag="VQ847_001099"
     CDS             6497..6937
                     /gene="adcR"
                     /locus_tag="VQ847_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3050446.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6937..7641
                     /locus_tag="VQ847_001100"
     CDS             6937..7641
                     /locus_tag="VQ847_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3050447.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7634..8440
                     /locus_tag="VQ847_001101"
     CDS             7634..8440
                     /locus_tag="VQ847_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3050448.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8450..9955
                     /gene="adcA"
                     /locus_tag="VQ847_001102"
     CDS             8450..9955
                     /gene="adcA"
                     /locus_tag="VQ847_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3050449.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11117..11890)
                     /locus_tag="VQ847_001103"
     CDS             complement(11117..11890)
                     /locus_tag="VQ847_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3050450.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            12066..13469
                     /locus_tag="VQ847_001104"
     CDS             12066..13469
                     /locus_tag="VQ847_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3050451.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13584..14222
                     /locus_tag="VQ847_001105"
     CDS             13584..14222
                     /locus_tag="VQ847_001105"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3050452.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14234..14674
                     /locus_tag="VQ847_001106"
     CDS             14234..14674
                     /locus_tag="VQ847_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3050453.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14667..15098
                     /locus_tag="VQ847_001107"
     CDS             14667..15098
                     /locus_tag="VQ847_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3050454.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15089..15559
                     /locus_tag="VQ847_001108"
     CDS             15089..15559
                     /locus_tag="VQ847_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3050455.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15584..16357
                     /locus_tag="VQ847_001109"
     CDS             15584..16357
                     /locus_tag="VQ847_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3050456.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16354..17154
                     /locus_tag="VQ847_001110"
     CDS             16354..17154
                     /locus_tag="VQ847_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3050457.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17213..19507
                     /locus_tag="VQ847_001111"
     CDS             17213..19507
                     /locus_tag="VQ847_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3050458.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19517..22633
                     /locus_tag="VQ847_001112"
     CDS             19517..22633
                     /locus_tag="VQ847_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3050459.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            22690..24456
                     /locus_tag="VQ847_001113"
     CDS             22690..24456
                     /locus_tag="VQ847_001113"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3050460.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            24602..25753
                     /locus_tag="VQ847_001114"
     CDS             24602..25753
                     /locus_tag="VQ847_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3050461.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            25898..26782
                     /locus_tag="VQ847_001115"
     CDS             25898..26782
                     /locus_tag="VQ847_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3050462.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
BASE COUNT         8384 a         4418 c         5704 g         8321 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aactaacttc ttagtactag ccaacaacga
      241 taatcataat tcctcctaaa attaggaata ataaaggcaa tagtttttgt tttttcatgt
      301 aaaaaacctc acttttgttt tctgctattt tatgctaaaa tattaaaaat caaatttaat
      361 tccaaagttt gtaactaaag ggggagcgct acatgtctaa ttcatttgtc aagttgttag
      421 tctctcaatt atttgcaaat ttagcagata ttttctttag agtaacaatc attgctaaca
      481 tatacattat ttcaaaatca gtaattgcca catcactagt tcctatctta ataggaatat
      541 cctcttttgt tgcgagtctt ttagttccgt tggttactaa aaggttagcg ctaaataggg
      601 ttttatcttt atctcaattt ggaaagacta tattattggc gatactggta ggaatgttta
      661 ccgtaatgca atccgtagcg cctttggtga cctatctatt tgttgttgca atttccatac
      721 tagatggttt tgcagcaccc gtttcctatg ctattgtgcc acgctatgcg accgatttgg
      781 gtaaggctaa ttcagcctta tcaatgactg gtgaagctgt tcaattgata ggttggggat
      841 taggtggact cttgtttgca acaattggtc tgttacctac cacgtttatc attttagtct
      901 tgtatatcat ttctagcttt ctgatgttat ttcttcctaa cgctgaagtg gaggtgttag
      961 agtcagaaac taatcttgaa attttgctca aaggttggaa gttagttgct agaaatccta
     1021 gattaagact ttttgtatca gcaaatttat tggaaatttt ttcaaatacg atttgggttt
     1081 cttccattat acttgttttt gtaacggagt tattaaataa aacggaaagt tactggggat
     1141 attctaatac agcatactct attggtatta taattagtgg cttaattgct tttaggctat
     1201 ctgaaaagtt ccttgctgct aaatgggaaa gtattctttt tcctcttgta gctatggcaa
     1261 tagtgacact gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt
     1321 tagttggtat gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag
     1381 tagaggaaaa tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat
     1441 tttcagtatt tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt
     1501 tttggctatc agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt
     1561 attttaaatg agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg
     1621 tgttgaaaaa acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg
     1681 aaatggagtt ttgaggcagg atcactctat ttgaaaatat acatagaaaa actgtataat
     1741 ccttaaaata agctgaaatc tattggaaac atacggtaaa caattgaaaa gatactatat
     1801 aaagtggtac aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat
     1861 tacagaaatg aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt
     1921 cggacagcct tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt
     1981 cagggtcaag gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt
     2041 caaataaacc aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta
     2101 gctatcctgt ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt
     2161 cggatagttt ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg
     2221 tttttggtgg ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc
     2281 atgcctacat tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag
     2341 tagcagagcc aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac
     2401 caatgataaa tctagctcag gttcaagaag cctttgccca agggaataac tatgaaatca
     2461 cgcatccagt caagggagat gataattact acattatctt tacttctggt acgactggta
     2521 agcctaaggg agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta
     2581 cggataagga atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt
     2641 ttgacttgtc tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc
     2701 ttccttcagt catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa
     2761 tcgctatctg gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca
     2821 acagtgagaa aatgcctgga atcacgcatt tctactttga tggtgaagaa ttgacggtca
     2881 aaacagctca aaaactgcgc gagcgtttcc caaatgcccg tatcatcaat gcttacggcc
     2941 caacagaagc gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc
     3001 tcaaacgcct accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg
     3061 aaggaaataa actgccaaat ggtgagcagg gagaaatcat tgtttctggg ccagctgttt
     3121 caaaaggtta tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaagatc
     3181 tgccagccta tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg
     3241 gcggacgcat ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct
     3301 ctcaaaacct caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca
     3361 aggaccacaa ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc
     3421 agtttgagcg agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga
     3481 tgtcctatat gatgccatct aaattccttt accgagacag tttgccacta actccaaatg
     3541 gaaagattga catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca
     3601 acagcttcct catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc
     3661 aaccttgccc atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt
     3721 ggtaagtctc ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc
     3781 cttgggtatt tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa
     3841 aagcaaggat ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat
     3901 ctttgtcaag gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat
     3961 ttcttacctt acctttcgtt cggttgggat tgtcatcgag ctgagagatg gagtgattaa
     4021 ggattttacc ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg
     4081 tccaatcgat cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga
     4141 gttgatggat atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt
     4201 tatcctagct catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca
     4261 gtcaggtggc ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggaact
     4321 cttctttgac tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat
     4381 ccgtagccct atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa
     4441 tcgctggcat atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat
     4501 ggtgttaacc agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat
     4561 tgtaaatatg ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg
     4621 actctttcat ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacgct
     4681 caataaggaa cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt
     4741 gcttggcatg gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt
     4801 cttgaataat ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag
     4861 ttattgaaat tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc
     4921 tttttgatgc aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga
     4981 accgttttga cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta
     5041 ataaaatcat agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc
     5101 ggaccggtct tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag
     5161 atgcatcata atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt
     5221 aaggagcgaa gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc
     5281 tttggctcta gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa
     5341 tacaatcgtt cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa
     5401 tattttggaa tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc
     5461 tcacctcagt ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat
     5521 ggagaccagt tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca
     5581 gcgactcgct tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg
     5641 gcaagtaaag aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt
     5701 aatgaacgcc aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat
     5761 aagcatgtag ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa
     5821 gatgttgtca aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat
     5881 tatttctata atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc
     5941 tttacctatc tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct
     6001 aaatctaagg taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat
     6061 gctggtctac gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttggaa
     6121 agtcaaggtt ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg
     6181 aaggacacca ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct
     6241 ttcctatcca atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa
     6301 gattgggcga cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga
     6361 gttcaagaat gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa
     6421 ttaactggta aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa
     6481 aggaaaggag tcagatatga gacagctagc aaaggatatc gatgcttttt tgaatgaggt
     6541 gattttgcag gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc
     6601 cctgaccaat actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc
     6661 agaattggcc cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt
     6721 ggtcaaggaa gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta
     6781 tcagttgact gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac
     6841 acttttaacc tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca
     6901 gcggtttttg actgctttag taggagaaat caaataatga gatatattac ggtagaggat
     6961 ttgtccttct attatgataa ggagcctgtt cttgaacata tcaattattg tgttgatagt
     7021 ggggaatttg ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggct
     7081 agtcttggaa ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa
     7141 ggtaagaaat tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt
     7201 ccaagtacgg tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt
     7261 cgtttgaatg ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg
     7321 gaacatcgag acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtgatt
     7381 gcgcgtatgt ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg
     7441 gatgcaggaa gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc
     7501 aaggctgttt tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat
     7561 attcatctag tccgtaacca agactcgcca tggcgttgtt tcaatgttca tgagaatggc
     7621 caggaggtgg gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc
     7681 ggttattgct atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca
     7741 gagtttgatg agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt
     7801 tttggggatt tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct
     7861 ggagtatctc cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc
     7921 aacaggtctg gctgtttctc tgattgtcat gagcaagggt aaaagctcga gttcaatgag
     7981 tttggaccaa tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct
     8041 ctttgtcatt gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat
     8101 cttaactttt gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat
     8161 tctttttaac atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct
     8221 tctggtatcg accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt
     8281 taaatcggtt atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta
     8341 catttcctac tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt
     8401 ctttatacta atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat
     8461 tagcttatta ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca
     8521 ggcagatggt aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca
     8581 agtcgcagga gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga
     8641 atacgaacca tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga
     8701 aaatgaaaac atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt
     8761 gaaaaccatc aaggcgacag gcgatatgtt gctcttgcca ggtggcaagg aagaagaggg
     8821 agaccatgac catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc
     8881 accagttcgt gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc
     8941 tgataaaaaa gagacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt
     9001 ggataaggct tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca
     9061 cgcagccttt aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact
     9121 ttctccagat gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa
     9181 aaataaaatc gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact
     9241 ttcaaaagaa gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga
     9301 ggacaccaag gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa
     9361 acaaacaaca gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac
     9421 agtccaaaat ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc
     9481 aggtaactgg caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga
     9541 ctacaaggct aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa
     9601 aggctatcag acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca
     9661 aggtggacaa agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa
     9721 gaaaggcaat cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt
     9781 caagtatgtt cagtttagtg accacaatgt tgccccagtt aaggcagaac atttccatat
     9841 cttctttgga ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta
     9901 ctacccagat aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga
     9961 aatcgactag ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata
    10021 gacctttcag aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag
    10081 aatgtagtta gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta
    10141 agggcttttt tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct
    10201 acttcttacc atctagccat ttgcagacga aatacaagat aattccagct ataacatctg
    10261 ctataatagt aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac
    10321 ccataggaac gtaatcggta accgatgaca aaagtattat atcacactaa atttagatca
    10381 tcaacctcac ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata
    10441 aggttcatta gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta
    10501 tcttagcgat ttaacgggtg tttataggct agtcactcgg tctacttctt actatctagc
    10561 catctgcaga cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg
    10621 agctctatga taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg
    10681 gtaaccgatg acaaaaatag tataccacaa tacatttaga tcatcaaggt cacttaattc
    10741 ttgaaatata gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt
    10801 gtgcaaaaac ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa
    10861 attgagtttt tgtccagcct ctgtttttag ggttgctgag aaaataatgt catgtggtga
    10921 atatttgtaa atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg
    10981 tcagcttcgt ctttccgtat atatgtgact gacttcatca gttctatcta caacctcaaa
    11041 acagtgtttc gagctgactt catcagtttt caaatctgta ctttgagcaa gctgagacta
    11101 gcttcctatt tgattttcat tgaatatcag aaacccattc tccatcaaat aattcgactg
    11161 cgtctaataa tttttgatct ggcacggtgt ctgaaataaa ggttgtgtat ttggagaggg
    11221 gattaatttt aaaaaatcca gtcttgtaaa atttagaact atcaatcagt aagatggttt
    11281 catgggcttt gtcaataata ttcttttttg aaatagcttg gctgagagaa gcttcataaa
    11341 catattggtc atcaatacct cttgctgaac aaaatgctaa atcgatatta aaatgatcta
    11401 ataaagaatt ttccttatca tagttgacca cggaacagga ttgatgtttg acctcgccag
    11461 atgtgataaa gattttggag ctatctttaa cagtttcaga tagggtttgt gcagtatgta
    11521 aaccatttgt aaaaataatc aaattatcaa gttcagaaag atagggacaa agttcgtaga
    11581 cagtagtact ggaatccaga taaacacaca taccagaccg aataaagtct ttagcgagac
    11641 tagcgattag tcttttttgc ctagtacttt ctccttcccg tatttgatga gaaagttcaa
    11701 ttgtgttcat agaggacagg gtcacgtatc cgtgctttct tttgataaga ccttgatttt
    11761 ctaagaaaat taaatcacga cgtaaggtac ttgtgctgga gaaagtgatt tctgccagct
    11821 cttttacggc aattcttttt ttctttttaa taatttcaat caattcaagt acacgttcat
    11881 cttttatcat aagctcctcc taatttatca tttcaactat attatagcac aaattggagg
    11941 aatttgaatt atttttatga atattgggtt aacatttgaa cattattcaa gtaagcgttc
    12001 acatattgaa aaaataaaac gtggggatta taataaagtt aatcaaggac gaagagagaa
    12061 gaaaaatgga agcggtttta gcaatagatt taggtgcgac ttctggaaga gcaatcgttg
    12121 gttacctttc tgaaaataaa ctagtaatgg aagaaataaa tcgcttttct aatctaccta
    12181 ttagagtaaa agggcattta tcttgggata ttgactttct actagctaaa attcttgaaa
    12241 gtatccgctt ggctaatact agttacaaga ttttatctat cggtattgac acatggggag
    12301 ttgattttgg actgattgat aatgaaggta agctgttatt acaacctgtt cattatcgtg
    12361 atgaaagaac aaagggagtg ttaaaggaaa tatctgaaat gactgaatta gaaaaactgt
    12421 attcagagac aggaaatcag attatggaga taaatacctt gtttcaactc tttaaggcac
    12481 gtcaagaatc tcctgactct ttctataaga ccaataagat tcttttaatg ccagatttgt
    12541 ttaattatct cttgacaggt aagtttgcta cagaaaaaag cattgcttca acaactcaat
    12601 tatttgatcc taggagtcaa aactggaatc agaatatctt aaaactattt gaattggatt
    12661 catctttact tcctgagatt gtttcagagg gaaatgttct tggaaggata aaaaaggagt
    12721 atggtttagg cgatattcct gttgtgaatg tttgtagtca tgatacagca agcgcgattg
    12781 tctcagtacc taagacagaa ggtagtttat ttatttcatc aggtacttgg tctttggttg
    12841 gagtggaact tacttcaccg cttcttacta ccgaatcctt cagttatgga tttacaaatg
    12901 aagtcggtaa agatggagtg attacatttc tgaagaattg tacagggttg tggatcatag
    12961 aggaactaag acgttcattt gaacgaagag ggaaagccta ttcttttgat gatattagga
    13021 caatggtgga gaaagaaaaa gaaaatcttc ctctgattga tactgaatca actgaatttg
    13081 caacagaatc tgatatgcac aagactttga cagaatatct agcttatcat catgaaacta
    13141 gagagtggac agatggacaa ctatttaaga ttgtttatga aagcctagct gaaacgtata
    13201 ggaaagcgat agagttacta gaagaactaa ctcataaggt ttataagagg atatatgtga
    13261 ttggaggagg tgctagagcc agttacttta accaaatgat tgctgataga actggtaaag
    13321 aggttcttac aggtttgact gaggctacag ctgtggggaa tattgttgtg cagctcatag
    13381 ctatgggaca attaaaaggg atggaagagg ctcaccatgt tattgaggag tttctacaat
    13441 tagagagtta ttactcccaa aagaattaaa aagattgaga gtttgtaaat ttgcctccct
    13501 cccccttctt agcttttgtg caggaagggg ggataattgg tgaattgaaa aatatttagt
    13561 gttttgatat gaggaggaca aggatgtcag atgtaaaaca agaattaatt aaatatggta
    13621 agaagctagt agaaacagat ttgacgaaag gaacaggtgg gaatctcagc gttttcgatc
    13681 gtgaaaaaca attgatggca attaccccgt cgggtattga tttctttgaa atcaaagaat
    13741 ccgatattgt agtgatggat attaatggaa atgttgtaga gggagaacgc ttgccatcta
    13801 gcgaatggta tatgcatttg attcaatatc aaactcgtga tgatatcgat gcaattatcc
    13861 atgctcatac aacttatgca acagtattag cttgtctcag agaaccactt ccagcgagtc
    13921 attatatgat tgcagtggca gggaaagatg ttcgggtagc tgagtatgca acatatggca
    13981 cgaaagaatt ggctgtgaat gcagctaaag caatggaagg tcgtagagca gttttactag
    14041 cgaatcatgg aattttagca ggtgcacaaa atttattgaa tgcatttaat attgttgaag
    14101 aagttgaata ttgtgcaaaa atttattgtt tagctaagaa ttttggagag ccagtagttc
    14161 ttcctgatga ggagatggaa ttgatggcag aaaaatttaa aacatacggt cagagaaaat
    14221 agggaggata ttaatgttaa aacatatacc gaaaaatatt tctccagatt tattgaagac
    14281 tttaatggaa atgggacatg gagatgaaat agtattagct gacgcgaatt atccttctgc
    14341 ctcatgtgca aataagctaa ttcgttgtga tggtgtaaat attccagaat tattagattc
    14401 cattctgtat ttaatgccat tagatagtta cgtcgatagt tcaattcagt ttatgaacgt
    14461 tgtttcgggt gatgatattc ctaagatatg gggtacctat agacagatga ttgaaggtca
    14521 tggtacagat cttaaaacga ttacttatct tagaagagaa gacttttatg aacgtagtaa
    14581 gaaagcttat gctattgttg ctacaggaga aacttcactt tatgctaata ttatccttaa
    14641 gaaaggagta gttgttgaaa gagaaaatgt ttaatagagg aattttagtt gccagtcatg
    14701 gtaattttgc tagcggagct ctcatgaccg cagaaatgtt tgttggtgag acaacaaatg
    14761 atagagttag gacattaggt ttgatgcctg gagagaatat tgtagagttt gaacattatt
    14821 ttaaaaatca agtaaatgaa ctgttagact caaatcaaga ggttatcgtt ttgactgact
    14881 tgattggagg aagtcctaat aatgtggctt tgtcacggtt tttaaatttg gattcagttg
    14941 atattgtaac agggtttaat atccctctcc tagtggaatt aatatcaagt tatgattcaa
    15001 aaatcaattt agaagaaatt gttcaaaatg ctcaaaatag tttgtttaat gttaaacaac
    15061 aacttaacgt agaggaggaa gaggatttat gtctatagag tttgttcgta ttgatgaccg
    15121 tctggtacat ggtcaagttg tcactacgtg gctaaaaaag tatgatattg agcaagttat
    15181 cattgttaat gatcgcatct cagaagataa aacacgacaa tctattttaa agatttctgc
    15241 accggtaggt ttaaaaattg ttttctttag tgtaaaacgg tttgtggaag ttttaaactc
    15301 tgtgccaata aaaaagagaa caatgctgat atatacaaat ccaaaagatg tgtatgattc
    15361 tattgaagga aatttaaaat tggagtacct caatgtagga cagatgagta aaacggagga
    15421 aaatgaaaag gtaacgggag gtgtagctct aggtgaagaa gacaaatatt attttaagaa
    15481 aatagttgat aagggaacga gagttgaaat tcaaatggtt cctaatgata aagttacaat
    15541 gttggaaaaa tttttataaa aataatttaa ggaggtacag tatatgctat tcacacaagc
    15601 attactggtg acattagttg ggattattgc cactattgac tataatggac cgttatttat
    15661 gattcaccgt cccttagtta caagtgcaat ggttggctta gtcttaggag atttcaccca
    15721 aggtgttctt attggttcag ctcttgaatt aacttggctc ggtgtaacag gtattggagg
    15781 ttacactcca ccagatacta tttcaggtgc gattattggt actgcatttg gtattttatc
    15841 tggtcaagga gaaactgctg gtatcgctat agcagttcca attgcagttg ctacccaaca
    15901 gttggatgtt cttgcaaaaa ctttagatgt ttattttgtg aaaaaagctg ataatgatgc
    15961 taaaaacgga gattattcaa agatcggttt ttatcattat tcaagtttgg ttttaatcac
    16021 gttatttaaa attgtaccaa ttttcctagc tattatgctt ggaggggaat atgtggcaga
    16081 cttgtttgct aaggttccac caatcgttat gcagggactt aactctgcag gtgctttact
    16141 accttcaatt ggttttggta tgcttttaaa tatgatgctc aagaaaaata tgtgggtatt
    16201 cttgttgatt ggattcattt gttctgtgta tggaggaatg tcaaccattg ggatctcact
    16261 agttggtatt gcggtagcat acttctacga tatgattgga agtaaaccac aagaaacaac
    16321 ttcaagtagt gatgttgagg aggatcttga tctatgatga ataataaagt aactaaagtt
    16381 gaacttaaaa aagttttcaa acgaagtttt atgtatggtt cttcatggaa ctatgagaga
    16441 atgcagaacc taggttttct atatacaatt cttccagtat tgaaaaaact atacccagac
    16501 aaagattcag cttctcctgc aatgaaacgt caccttgagt ttttcaatac tcatcaaaca
    16561 gcggcaccat ttattcttgg agttacttcc gctatggaag aacaagaagg aaatgaaggt
    16621 gcagcttcaa ttactggtat taaagttggc ttgatggggc cactggctgg tctaggagat
    16681 agtttgttct ggctgacact agttcctatc tgttttagta ttggtgcgtc ttattctaaa
    16741 gacggcggtg ctttaggtat ctttatcgcc ttaatattgt ttaatattat taatattcct
    16801 gttaaatatt tcggtttgaa atatgggtat actaagggtt ctagtcttat ccaagaaaat
    16861 aatacaaaag gaacattgaa tcgcgttacg agtatggcga cagcattagg gctagtacta
    16921 gtgggtggtt tgattccatc aatggttggt attaattttg gattagaatt taagcagggg
    16981 gaacttgtta tttctgttca agaaatgatt acaaaattaa ttccaggatt tatccctatg
    17041 gctttgactt tattaatgtg taaattaatt agaaaaggaa agaatccggt tgtactaatc
    17101 tttagtgtta tggctattgg agttatccta gttgttttag gaattttgaa gtagtagaaa
    17161 gtgtggaggt ggtatttggg atatcacctc cattttggaa gagaggtaaa gagtgaaatt
    17221 atggtataag aaagctgccg caaattggaa tgaagccttg ccgattggga acggtcattt
    17281 aggtggtatg atttatggtt cagctacaaa agaatgtatt caactaaacg atgagactat
    17341 ttggtataga ggaaagtcag atagaaataa tccagactca ctattgcatc ttaaaaaaat
    17401 tcgggaatat cttttagatg gagaaattca gaaagccgaa gaattgataa agttaacaat
    17461 gtttgctacc ccaagagatc aaagccacta tgaattactt ggggaacttt acattgagca
    17521 tatagatatt cagtcttgtg ctctttcatt gtatgaaaga gagctagatt tagatacagc
    17581 tatttctaat gttgtgtttg agcctaatag ttgtaattta caaataaaaa gagaatattt
    17641 tacgagtttt aataagaata ttttatgttg ccgtatagtg tcatcagttc aaaacacatt
    17701 aaatttaaac attaatttgg gtagaaataa acggtttaat gacgaagtat ctaaactgga
    17761 ttcaagtaca attttaatgt cggcctctgc tggaggtaga aaaggtgttc agtttaaagt
    17821 agtatgtcat tctaaggtta cggatggtga agtaagtgta ttgggagaga caatagttat
    17881 tcggaatgct acagaggtat ttctttatct caaatcaatg acggattatt ggggaaatat
    17941 agatatttct tctcttcagg gagaatttag tagtattgat tactttacag aaaaagatga
    18001 acatgtaaaa aaatatcagg agcaatttaa tagagttgat tttaaactag actatagtaa
    18061 aggttgtctt agcattccaa cgaatctact tcttgaaaac actaaaaagt atagtaacta
    18121 cttgactaac ttgttatttc attatggaag atatctgtta atatcgtcta gtcaaccgaa
    18181 tggtttacct gccaatcttc aaggaatatg gtgtgatgaa ttaaatccaa tttggggttc
    18241 taaatatacg attaatatta atactcaaat gaattattgg atggtaggtc catgtgattt
    18301 accagaagta gaatatccat tatttgatat gctcgaaaga atgagagaac cgggaagact
    18361 aaccgctaag aaaatgtatg gagctagagg ttttacagca catcataata cggatggttt
    18421 tggcgatacg gctccccaat ctcatgccat gggggctgca atttgggtat taactattcc
    18481 atggttatgt actcatattt gggaacacta tttatatttc caagatgagc gtattcttac
    18541 ggaacatttt gaaatgataa aagaagcatt tcttttcttt gaagattatt tatttgaggt
    18601 ggatggctac ttgatgacag gtccaagtgt ctcaccggaa aataaatatc gcttaaaaaa
    18661 tggtattgaa ggaaatgctt gtctatcatc tacaattgat aatcaaattt taagatattt
    18721 ttgtgattca tgcattggaa ttgcaaaaca attaggagac aattcggatt ttattagtcg
    18781 tgtgaaggag ttaaaaaaga aactacctaa aacaaaaata ggtagtaatg ggcaaatcca
    18841 agaatggtta gaagattatg aagaagtaga gcctgggcat agacacattt cacctctatt
    18901 tgggctttat ccttataatg agattgatat tcataaaact ccggaattag cagaagcagc
    18961 taaaatcact atcaatagga gattatcaaa cgctaacttt ttatcttcac aggagaggga
    19021 gcaagcgatt aataattggt tagtaagtgg tttgcatgct agtacacaaa caggttggag
    19081 tgctgcatgg ctgattcatt tttttgcgag actatatcaa ggtgaacctg cttataacca
    19141 gattaatggt ttgttaaata atgcgactct tggcaattta tttcttgacc atccaccatt
    19201 tcaaattgat ggtaatttag gtttggtgag tggaatttgt gaattattag tacagagcca
    19261 tcataattgg ttatcactaa ttccagcttt accttctgct tggtcagaag gagaagtgaa
    19321 aggtttcaga gtaagaggag gatataaggt atcgtttgct tggaaaaatg gggatataac
    19381 attcctaaaa ttggaaggag gaaacaaaga tcaaaaagta agagtaagaa tatatggcaa
    19441 aaatactgat gtacaaaata ttgaattggt atttaattca gaaaaaatta ttgagttaaa
    19501 tttttaggta taagtcatga ataaagaaaa aataaaaaga aaattaatca caatactgtt
    19561 tgtatgtatt gggatgttat gttttggatt gttagcagga gttaaggctg ataatcgtgt
    19621 tcaaatgaga acgacgatta ataatgaatc gccattgttg ctttctccgt tgtatggcaa
    19681 tgataatggt aacggattat ggtgggggaa cacattgaag ggagcatggg aagctattcc
    19741 tgaagatgta aaaccatatg cagcgattga acttcatcct gcaaaagtct gtaaaccaac
    19801 aagttgtatt ccacgagata cgaaagaatt gagagaatgg tatgtcaaga tgttggagga
    19861 agctcaaagt ctaaacattc cagttttctt ggttattatg tcggctggag agcgtaatac
    19921 agttcctcca gagtggttag atgaacaatt ccaaaagtat agtgtgttaa aaggtgtttt
    19981 aaatattgag aattattgga tttacaataa ccagttagct ccgcatagtg ctaaatattt
    20041 ggaagtttgt gccaaatatg gagcgcattt tatctggcat gatcatgaaa aatggttctg
    20101 ggaaactatt atgaatgatc cgacattctt tgaagcgagt caaaaatatc ataaaaattt
    20161 ggtgttggca actaaaaata cgccaataag agatgatgcg ggtacagatt ctatcgttag
    20221 tggattttgg ttgagtggct tatgtgataa ctggggctca tcaacagata catggaaatg
    20281 gtgggaaaaa cattatacaa acacatttga aactggaaga gctagggata tgagatccta
    20341 tgcatcggaa ccagaatcaa tgattgctat ggaaatgatg aatgtatata ctgggggagg
    20401 cacagtttat aattttgaat gtgccgcgta tacatttatg acaaatgatg taccaactcc
    20461 agcatttact aaaggtatta ttcctttctt tagacatgct atacaaaatc cagctccaag
    20521 taaggaagaa gttgtaaata gaacaaaagc tgtattttgg aatggagaag gtaggattag
    20581 ttcattaaac ggattttatc aaggacttta ttcgaatgat gaaacaatgc ctttatataa
    20641 taatgggaga tatcatattc ttcctgtaat acatgagaaa attgataagg aaaagatttc
    20701 atctatattc cctaatgcaa aaattttgac taaaaatagt gaggaattgt ctagtaaagt
    20761 caactattta aactcgcttt atccaaaact ttatgaagga gatgggtatg ctcagcgtgt
    20821 aggtaattcc tggtatattt ataatagtaa tgctaatatc aataaaaatc agcaagtaat
    20881 gttgcctatg tatactaata atacaaagtc gttatcgtta gatttgacgc cacatactta
    20941 cgctgttgtt aaagaaaatc caaataattt acatatttta ttgaacaatt acaggacaga
    21001 taagacagct atgtgggcat tatcaggaaa ttttgatgca tcaaaaagtt ggaagaaaga
    21061 agaattagag ttagcgaact ggataagcaa aaattattcc atcaatcctg tagataatga
    21121 ctttaggaca acaacactta cattaaaagg gcatactggt cataaacctc agataaatat
    21181 aagtggcgat aaaaatcatt atacttatac agaaaattgg gatgagaata cccatgttta
    21241 taccattacg gttaatcata atggaatggt agagatgtct ataaatactg aagggacagg
    21301 cccagtccct ttcccaacac cagataaatt taatgatggt aatttgaata tagcatatgc
    21361 aaaaccaaca acacaaagtt ctgtagatta caatggagac cctaatagag ctgtggatgg
    21421 taacagaaat ggtaatttta actctggttc ggtaacacac actagggcag ataatccctc
    21481 ttggtgggaa gtcgatttga aaaaaatgga taaagttggg cttgttaaaa tttataatcg
    21541 cacagatgct gagactcaac gtctatctaa ttttgatgtg attctatatg acaataatag
    21601 aaacgaagtt gctaagaaac atgttaataa tttgtcgggt gaatctgtta gtctagattt
    21661 caaagaaaaa ggagcaaggt atattaaagt taaattacta acgagtggag tgcctttgag
    21721 tttagcagaa gtagaggttt ttagagaatc agatggtaag caatctgaag aggatataga
    21781 taaaataaca gaagataaag tagtctctac aaataaggta gctactcaaa gttcaaccaa
    21841 ttatgagggt gtagctgctt tagcagttga tggtaataaa gatggagatt acggacatca
    21901 ttcggtgact catactaagg cagattctaa cgcttggtgg caggtcgatc tgggagaaga
    21961 gtttacggtt tctaaagttg atatttataa tagaacagat gccgaacctc agcgtttatc
    22021 taattttgat gttatttttc tatcttcatc aggagaagaa gtttttagaa gacattttga
    22081 taaagtagtt gatggtttgt tatctttaaa agtaccttct gtaggggcta agctagtcaa
    22141 aatagaatta aaatcagcag ctattccgtt aagtttagcg gaagttgaag tctatggttc
    22201 aaagagaact ccgaagaaac tttctaatat tgcattaacc aaagaaactc gacagagttc
    22261 aacggattac aatggttttt ctcgtctagc agttgatgga aataaaaacg gagattatgg
    22321 tcatcattca gtgactcata ccaaaggaga ttctccttca tggtgggaga tagatttagc
    22381 acaaaccgaa gaattagaaa agttaattat ttataataga acagatgctg aaattcagag
    22441 attatcaaat tttgatatta ttatatatga ttcaaataat catgaagttt ttaaacaaca
    22501 tattgacagt ttagaaagca ataatctatc catagactta aaagggctga agggaaaaaa
    22561 ggttagaatt tctttgagaa acgcaggaat tcctttaagt ttggcagagg tagaggttta
    22621 tacttataag taattttaaa aattatcatc ggtagtatga aagaaacaga aaaataagag
    22681 gaaaatagta tgattcaaca tccacgtatt gggattcgtc cgactattga tggtcgtcgt
    22741 caaggtgtac gcgaatcact tgaagtacaa acaatgaaca tggctaaaag tgtggcagat
    22801 ttgatttcaa gcacattgaa atatccagat ggggaacctg tggaatgcgt gatttctcca
    22861 tctactattg gccgtgtacc agaggctgca gcttcccatg agttgttcaa aaaatcaaat
    22921 gtttgcgcaa caattacagt tacaccatgc tggtgttatg gtagtgaaac tatggatatg
    22981 tctccagata ttcctcatgc tatttgggga tttaatggga cagaacgccc aggagctgtc
    23041 tatcttgcag ctgtactagc ttcacatact caaaaaggga ttccagcctt tgggatttat
    23101 ggtagagatg ttcaggaagc taatgataca gctattccag aagatgtcaa agaaaaactt
    23161 ttacgttatg cgcgggcagc tcttgcaact ggcttgatga gagacactgc ttacctatca
    23221 atgggtagtg tttcgatggg gattggtggt tctattgtaa atccggattt cttccaagaa
    23281 tacttaggaa tgcgaaatga atcggtagat atgacggagt tcacacgccg tatggaccgt
    23341 ggtatttacg accctgaaga gttcgaacgt gcgctcaaat gggtgaaaga aaacgtaaaa
    23401 gaaggattcg accataaccg tgaagacctt gttttaagcc gtgaagaaaa agatagacaa
    23461 tgggaatttg ttattaagat gttcatgatt ggacgtgact taatggttgg taacccaaga
    23521 cttgctgaac ttggttttga ggaagaagca gttggtcacc atgctttagt agctggtttc
    23581 caaggtcaac gtcagtggac agaccatttt ccaaatggag attttatgga aactttcctc
    23641 aatactcagt ttgactggaa tggtattcga aaaccatttg tatttgcgac agagaatgat
    23701 tcactaaatg gtgtgtctat gctctttaat tatctattaa caaatactcc acaaatcttt
    23761 gctgatgtgc gtacttattg gagtccagag gctgttgaac gtgtaacagg atatacttta
    23821 gagggtcgtg ctgcagctgg cttcttacat ctaatcaact ctggttcttg tacattagat
    23881 ggtacaggtc aagctactcg agatggcaaa cctgttatga aaccattctg ggagttggat
    23941 gaaagtgaag tgcaggctat gcttgaaaat acagacttcc caccagcaaa ccgcgaatac
    24001 ttccgtggag gaggattctc aactcgtttc ttgacgaagg gggatatgcc agtaacaatg
    24061 gtacgtctca atcttctaaa aggggttggt ccagtgctac aaattgcaga aggttataca
    24121 cttgaacttc ctgaagatgt tcaccatact ttagataatc gtacagatcc aggatggcca
    24181 actacttggt ttgctccacg tttgacagga aaaggtgctt tcaagtctgt ctatgacgtc
    24241 atgaataatt ggggagctaa tcacggagcc ataacatatg gacacattgg agcagacttg
    24301 attaccttgg cttctatgtt gagaattcct gtcaatatgc ataatgtacc tgaggaagat
    24361 atctttagac ctaaaaattg gtccttattt ggaacagaag atctagaatc agcagactat
    24421 cgtgcatgtc agttgttggg accactacat aaataaaact tgtttatata ggaggtgaac
    24481 ttacgtccct cctatccttt taaaaagatt tgttaaacaa ttcacaaata attgaaaacg
    24541 aatacaaaaa gtaatataat gatgttaaat agatagcgcg gaggcgcagg aggaaaatta
    24601 tatggctaca ttttatgttc cggcagtcaa ccttattgga aaaggtgttg taaatgaagt
    24661 gggtccttat atcaaggaac ttggctataa aaaggcactt ttggtgacag ataagtacat
    24721 cgaaggcagt gatattttac ctaagacttt aaaaccactg gatacagaag gaatcgaata
    24781 tgtcatcttt agcgatgtag agccaaaccc tacttgtaag aatgtcacag atggggtagc
    24841 tgctttgcaa gaacatggat gtgattttat catcagtctt ggcgggggtt ctccacagga
    24901 tgcagctagt tgtatttcta tcatggctac aaatggtgga aaaccacagg attatgaagg
    24961 gcttcataag tctgctaaaa aaggcttgcc agttgtggct atcaatacaa cggcaggaac
    25021 ttctgcagaa atcactatta actatgtgat tactgatgaa gaacgcaagg ttaagatggt
    25081 aatggttgac aagaatagcc ttgctcttat ctctgttaat gacccggaac tcatgctttc
    25141 caaacctaaa ggtctgactg ctgctactgg tatggatgct ctgactcacg ctgttgaagc
    25201 tttggtaaca cctggtgctt atgatgtaac caagaaactg tctattggtg ctattgagct
    25261 tatcaaggaa tatcttcctc gtgctgtaga aaatggacat gatattgaag cgcgtgaagg
    25321 tatggtcaat gccatcttcc ttggtggtat gagctttaat aatgctggtc ttggttatgt
    25381 tcactcaatg gctcaccaac tcggtgcagt atataatttg ccacatggtg tttgctgtgc
    25441 catgttgcta ccagttatag aacgtgaaaa tgctaaacgt gtaccagaag ctttccgcaa
    25501 tgttgccaaa gccttgggcc ttcatgtgga aggtaaatca gatcaagagt gtgccgatta
    25561 tgcgattgct gagattgaga agctttctga gacagtaggt attcctaaga aattgactga
    25621 acttggtatt gaagaaaaag atttcgactt tgaatacctt tctaagaatg ccttgattga
    25681 tgcctgcgca ccaggaaatc catttatgcc aaccttagaa gaaacgattg ccttttataa
    25741 agagttattt tagcaagaga ttagacgaca ataggacaat tcacctctaa ttattgacat
    25801 ttcaggaaaa atcgcagtaa aaacggcaca gccttcttta aatgtgctat aatactagaa
    25861 aaatacttgt ggaggttcca ttatggcaat atttttcatg atttttctga ttgtttgtgt
    25921 gctcctattg gtgatagtca cactgagtac agtttatgtg gttcgtcagc agtcggtggc
    25981 gattattgaa cgctttggga aataccaaaa ggttgctaat agcggtattc atattcgctt
    26041 gccttttggg attgactcga ttgcagcacg gattcagttg cgcttgttgc aaagtgatat
    26101 tgtggttgag actaagacca aggacaatgt gttcgttatg atgaatgtag cgactcagta
    26161 ccgtgtcaac gagcagagcg tgacagatgc ttactataaa ctcatacgtc cagaatctca
    26221 gattaaatct tatatcgaag atgctcttcg ctcttctgtt ccaaaattaa ccttggatga
    26281 attgtttgag aaaaaagatg agattgccct tgaggttcaa caccaagtag cagaagaaat
    26341 gaccacttac ggctacatta tcgtgaaaac cttgattacc aaggtcgaac cagatgcaga
    26401 agttaagcaa tctatgaatg aaatcaatgc ggcgcaacgt aagcgggtcg cagcacaaga
    26461 attggcggaa gctgacaaga ttaaaattgt cactgcagct gaagccgaag cagaaaaaga
    26521 ccgccttcat ggtgtgggga ttgcccaaca acgtaaggcg attgtggatg gattggcaga
    26581 gtctatcacc gaactcaagg aagccaatgt tggcatgaca gaagaacaaa tcatgtctat
    26641 cctcttgacc aaccagtatt tggatacctt gaataccttt gcctctaaag gaaatcaaac
    26701 catcttttta ccaaatactc caaatggtgt ggatgatatc cgtacacaaa tcttgtcagc
    26761 ccttcgcgct gagaagaaat aatagactaa tactcttcga aaatctcttc aaactacgtc
    26821 agcgtcg
//
LOCUS       DAVBNN010000025        26014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBNN010000025 DAVBNN010000000
VERSION     DAVBNN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.025"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ847_001116"
     CDS             complement(15..311)
                     /locus_tag="VQ847_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050463.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ847_001117"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ847_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3050464.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ847_001118"
     CDS             complement(3584..4810)
                     /locus_tag="VQ847_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3050465.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ847_001119"
     CDS             complement(4853..5545)
                     /locus_tag="VQ847_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3050466.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ847_001120"
     CDS             complement(5731..7482)
                     /locus_tag="VQ847_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050467.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ847_001121"
     CDS             complement(7472..9217)
                     /locus_tag="VQ847_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3050468.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ847_001122"
     CDS             complement(9423..9719)
                     /locus_tag="VQ847_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3050469.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ847_001123"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ847_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ847_001124"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ847_001124"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3050470.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ847_001125"
     CDS             11300..11443
                     /locus_tag="VQ847_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3050471.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ847_001126"
     CDS             11443..11682
                     /locus_tag="VQ847_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3050472.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ847_001127"
     CDS             12560..13141
                     /locus_tag="VQ847_001127"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3050473.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ847_001128"
     CDS             13141..14403
                     /locus_tag="VQ847_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3050474.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ847_001129"
     CDS             complement(14490..15356)
                     /locus_tag="VQ847_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3050475.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ847_001130"
     CDS             complement(15343..16113)
                     /locus_tag="VQ847_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3050476.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ847_001131"
     CDS             complement(16139..16993)
                     /locus_tag="VQ847_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3050477.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ847_001132"
     CDS             complement(17150..17554)
                     /locus_tag="VQ847_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3050478.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ847_001133"
     CDS             complement(17624..19105)
                     /locus_tag="VQ847_001133"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3050479.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ847_001134"
     CDS             complement(19124..20302)
                     /locus_tag="VQ847_001134"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3050480.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ847_001135"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ847_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3050481.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ847_001136"
     CDS             complement(21519..22556)
                     /locus_tag="VQ847_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3050482.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ847_001137"
     CDS             complement(22557..22910)
                     /locus_tag="VQ847_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3050483.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ847_001138"
     CDS             complement(23154..24044)
                     /locus_tag="VQ847_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3050484.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ847_001139"
     CDS             24177..24713
                     /locus_tag="VQ847_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3050485.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ847_001140"
     CDS             complement(24879..25685)
                     /locus_tag="VQ847_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3050486.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7804 a         5737 c         4613 g         7860 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagacc
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaatgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgagc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gttt
//
LOCUS       DAVBNN010000026        23842 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBNN010000026 DAVBNN010000000
VERSION     DAVBNN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.026"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(98..2356)
                     /locus_tag="VQ847_001141"
     CDS             complement(98..2356)
                     /locus_tag="VQ847_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3050487.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VQ847_001142"
     CDS             complement(2585..2815)
                     /locus_tag="VQ847_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3050488.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VQ847_001143"
     CDS             3005..3688
                     /locus_tag="VQ847_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3050489.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VQ847_001144"
     CDS             3688..4422
                     /locus_tag="VQ847_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3050490.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VQ847_001145"
     CDS             4576..5433
                     /locus_tag="VQ847_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3050491.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VQ847_001146"
     CDS             5575..6447
                     /locus_tag="VQ847_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3050492.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ847_001147"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ847_001147"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3050493.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VQ847_001148"
     CDS             7426..8637
                     /locus_tag="VQ847_001148"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3050494.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VQ847_001149"
                     /pseudo
     CDS             8639..9181
                     /locus_tag="VQ847_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9197..10006
                     /locus_tag="VQ847_001150"
     CDS             9197..10006
                     /locus_tag="VQ847_001150"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3050495.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..11213
                     /locus_tag="VQ847_001151"
     CDS             10482..11213
                     /locus_tag="VQ847_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050496.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11259..11462
                     /locus_tag="VQ847_001152"
     CDS             11259..11462
                     /locus_tag="VQ847_001152"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3050497.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11999
                     /locus_tag="VQ847_001153"
     CDS             11487..11999
                     /locus_tag="VQ847_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3050498.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12657..13367
                     /gene="deoD"
                     /locus_tag="VQ847_001154"
     CDS             12657..13367
                     /gene="deoD"
                     /locus_tag="VQ847_001154"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3050499.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13390..13914)
                     /locus_tag="VQ847_001155"
     CDS             complement(13390..13914)
                     /locus_tag="VQ847_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3050500.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13967..14203)
                     /locus_tag="VQ847_001156"
     CDS             complement(13967..14203)
                     /locus_tag="VQ847_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3050501.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14271..15191)
                     /locus_tag="VQ847_001157"
     CDS             complement(14271..15191)
                     /locus_tag="VQ847_001157"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3050502.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15389..15793
                     /locus_tag="VQ847_001158"
     CDS             15389..15793
                     /locus_tag="VQ847_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050503.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16009..16590
                     /locus_tag="VQ847_001159"
     CDS             16009..16590
                     /locus_tag="VQ847_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3050504.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16587..17864
                     /locus_tag="VQ847_001160"
     CDS             16587..17864
                     /locus_tag="VQ847_001160"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3050505.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17882..18544
                     /gene="deoC"
                     /locus_tag="VQ847_001161"
     CDS             17882..18544
                     /gene="deoC"
                     /locus_tag="VQ847_001161"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3050506.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18531..18920
                     /locus_tag="VQ847_001162"
     CDS             18531..18920
                     /locus_tag="VQ847_001162"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3050507.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19011..20063
                     /locus_tag="VQ847_001163"
     CDS             19011..20063
                     /locus_tag="VQ847_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3050508.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20207..21742
                     /locus_tag="VQ847_001164"
     CDS             20207..21742
                     /locus_tag="VQ847_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050509.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21735..22793
                     /locus_tag="VQ847_001165"
     CDS             21735..22793
                     /locus_tag="VQ847_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050510.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22796..23752
                     /locus_tag="VQ847_001166"
     CDS             22796..23752
                     /locus_tag="VQ847_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050511.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6918 a         4300 c         5437 g         7187 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttcgtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggaatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acttgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaatga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa ttatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggaactt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctagg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggatgctacc
    10741 tagctcagat tgcagaggtt gaagcttacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttggaatg
    10861 ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aatgatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa taggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa actttcaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaggataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgatagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 taggactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca gtgggaaaaa
    12421 gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc ttcgcttttt
    12481 gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag agcgtgtgtt
    12541 ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa aatcaggatt
    12601 tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca taaattatgt
    12661 ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt cctggggatc
    12721 ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt tttaacgaag
    12781 tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct gtcatgggaa
    12841 ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta gactacggtg
    12901 tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt catgttcgtg
    12961 aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat gactggccac
    13021 agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac catatcgcca
    13081 aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc ttttactcaa
    13141 attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg gaaatggaag
    13201 cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct atcatgacca
    13261 tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt caaaatacct
    13321 tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta tagccaaaaa
    13381 ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat ctagctctct
    13441 ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt ggtaattttc
    13501 tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc agtcaaagcg
    13561 ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa gataacgctt
    13621 aaaggctcta aagagacagg tcaatggcaa aaaattgaga aagatgattt ggtcagcttc
    13681 ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc aagctttatg
    13741 cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt cttgccaacc
    13801 aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt tagataactt
    13861 ttctgctaga gttgacttac cagaaccaga atatccgata attgtgattt tcattttcta
    13921 ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat ttagcaagtt
    13981 tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa cctttagttt
    14041 ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg tttgcttcga
    14101 aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg ttttgtttaa
    14161 cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt acctccatat
    14221 ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa ttattttttt
    14281 aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc tgcacgattt
    14341 ctggttggtt caatataatt ttgtagattt gtgagattga tactggtcca gacctgatgg
    14401 gcaaaggctt ccacttcccc aatcggcatc tgagtaaaac gataatagta gctatcaggg
    14461 tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact ttcaatatca
    14521 tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata gagacgatcg
    14581 ttttgtggat tttgaaagac attgattccc tcaacaatta caaaatcagc agctttgaca
    14641 ctttgtttct cttcgggtac gatgtcgtaa acttcatgag aatagacagg aatatctaca
    14701 tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc atagctttca
    14761 ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg atagagaaaa
    14821 ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag taggatttga
    14881 agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc aataataaaa
    14941 ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa atcttcctta
    15001 gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt aacgtcttgg
    15061 agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt caaaggaggt
    15121 gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa atgtaaaaat
    15181 tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa atctaaaaaa
    15241 ataaagcggt ttcttgaatg tggtaagtca atggtatata gtataagtga tcaatttatt
    15301 gatgaaatag gagatagatt ctactgattt ataagtttat aagcttataa agggggcttt
    15361 ttagttcaca acttatagga ggtgtactat gaaaatctta aaacgttaca tattggaact
    15421 ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag ataatggtat
    15481 atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc
    15541 tgtctttatc tattcgtttt taattgcttt cttactaaaa aaacgatggg cgaaatggat
    15601 tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg
    15661 catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta
    15721 tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa agtattttaa
    15781 ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc
    15841 tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga aagagattga
    15901 agaaaatggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc aatttgtaaa
    15961 cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca
    16021 gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa
    16081 atgacctttt taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa
    16141 ctattgctca agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt
    16201 tacggacctt tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat
    16261 atcaacactc gtgccttgga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg
    16321 acgattttcc agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc
    16381 aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat
    16441 ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt
    16501 gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaggga
    16561 tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag
    16621 acggtcaaga actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa
    16681 ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga
    16741 ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt
    16801 cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa
    16861 ccttgattct agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc
    16921 gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag
    16981 tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg
    17041 ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg
    17101 caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag
    17161 gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg
    17221 atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga
    17281 cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg
    17341 aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta
    17401 tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaagact gttgaagaag
    17461 ttcgccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc
    17521 aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc
    17581 ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca
    17641 tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg
    17701 tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca
    17761 caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg
    17821 atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga
    17881 aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca
    17941 aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc
    18001 gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt
    18061 agtaggtttc cctttgggag caacaacttc agccgtgaaa gcatttgaga caaaagaagc
    18121 tatccaaaat ggtgcagatg agattgatat ggtgatcaat gttggagctc tcaaatcagg
    18181 taatttagcc ttggttgagt cagatattcg cgcagtagtg gaagcaagtg gtgataagtt
    18241 agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaaattg ttgtttgcca
    18301 attggcccaa aaagctgggg ctgactttgt taaaacatct actggttttt caactggtgg
    18361 tgctacgata gcagatgtta cattaatgcg tgaaacagtt ggatctgata tgggagtcaa
    18421 ggctgctggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac
    18481 ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta
    18541 ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact
    18601 ttcctatcgg agcagtttta gtagccaaag acggaaatgt ttacacggga gtgaatatcg
    18661 aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat
    18721 ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgattt
    18781 caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat ttaaaagtga
    18841 ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta cttccatatt
    18901 cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct ttgtgaccaa
    18961 tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatctttg
    19321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    19381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    19681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    19741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    19801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    19861 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    19921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    19981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20341 gtccacgcta atgaacatgt tagcagggct tcttgaacca actagtggtg aaatcgcggt
    20401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    20641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    20701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    20761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    20821 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    20881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtagggcgtt ctgtttcctt
    20941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21241 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21481 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    21661 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    21721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    21781 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    21841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    21901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    21961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22021 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22261 atgcaactta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    22681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    22741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    22801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    22861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    22921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    22981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23401 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    23641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    23701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    23761 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    23821 ttggggtgtt tttattatga aa
//
LOCUS       DAVBNN010000027        23291 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBNN010000027 DAVBNN010000000
VERSION     DAVBNN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.027"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            60..929
                     /locus_tag="VQ847_001167"
     CDS             60..929
                     /locus_tag="VQ847_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3050512.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VQ847_001168"
     CDS             933..1889
                     /locus_tag="VQ847_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3050513.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VQ847_001169"
     CDS             1889..2653
                     /locus_tag="VQ847_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050514.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VQ847_001170"
     CDS             2653..3363
                     /locus_tag="VQ847_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050515.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3671..4327
                     /locus_tag="VQ847_001171"
     CDS             3671..4327
                     /locus_tag="VQ847_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3050516.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4435..5530
                     /gene="prfB"
                     /locus_tag="VQ847_001172"
     CDS             join(4435..4506,4508..5530)
                     /gene="prfB"
                     /locus_tag="VQ847_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3050517.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5548..6240
                     /gene="ftsE"
                     /locus_tag="VQ847_001173"
     CDS             5548..6240
                     /gene="ftsE"
                     /locus_tag="VQ847_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3050518.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6233..7159
                     /locus_tag="VQ847_001174"
     CDS             6233..7159
                     /locus_tag="VQ847_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050519.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            7445..9625
                     /locus_tag="VQ847_001175"
     CDS             7445..9625
                     /locus_tag="VQ847_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3050520.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9677..10492
                     /locus_tag="VQ847_001176"
     CDS             9677..10492
                     /locus_tag="VQ847_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3050521.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            10632..11975
                     /locus_tag="VQ847_001177"
     CDS             10632..11975
                     /locus_tag="VQ847_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3050522.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            12352..13542
                     /locus_tag="VQ847_001178"
     CDS             12352..13542
                     /locus_tag="VQ847_001178"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3050523.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            14095..15030
                     /locus_tag="VQ847_001179"
     CDS             14095..15030
                     /locus_tag="VQ847_001179"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3050524.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            15064..16101
                     /locus_tag="VQ847_001180"
     CDS             15064..16101
                     /locus_tag="VQ847_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3050525.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            16274..16879
                     /locus_tag="VQ847_001181"
     CDS             16274..16879
                     /locus_tag="VQ847_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3050526.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            17035..17565
                     /locus_tag="VQ847_001182"
     CDS             17035..17565
                     /locus_tag="VQ847_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3050527.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            17586..18671
                     /gene="rlmN"
                     /locus_tag="VQ847_001183"
     CDS             17586..18671
                     /gene="rlmN"
                     /locus_tag="VQ847_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3050528.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            18671..19153
                     /locus_tag="VQ847_001184"
     CDS             18671..19153
                     /locus_tag="VQ847_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3050529.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            19155..20696
                     /locus_tag="VQ847_001185"
     CDS             19155..20696
                     /locus_tag="VQ847_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3050530.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(20752..21555)
                     /locus_tag="VQ847_001186"
     CDS             complement(20752..21555)
                     /locus_tag="VQ847_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3050531.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(21638..21859)
                     /locus_tag="VQ847_001187"
     CDS             complement(21638..21859)
                     /locus_tag="VQ847_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050532.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(22338..22547)
                     /locus_tag="VQ847_001188"
     CDS             complement(22338..22547)
                     /locus_tag="VQ847_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050533.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            22717..22989
                     /gene="rpsP"
                     /locus_tag="VQ847_001189"
     CDS             22717..22989
                     /gene="rpsP"
                     /locus_tag="VQ847_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3050534.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            23009..23248
                     /locus_tag="VQ847_001190"
     CDS             23009..23248
                     /locus_tag="VQ847_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3050535.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT         6969 a         4224 c         5092 g         7006 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaacccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttgggcat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa atcaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctaggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gccttacaaa tggtgcggca ggtattttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gtcgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc atcaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttaaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttggccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa tgccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agcaaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagaa acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac tcgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcagggacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gaccttttta gtcggtagat tgagattgca aacaaatatg catctacatt
     3481 gaaagcttaa tttctaataa ttgaaaaaat cgaatgaaaa atttcttacc ttcattcaca
     3541 gagctctatt tcagagctct ttttgctagc ttattcatac ttttctgaat ttcgaaaaag
     3601 aaatgtaagc gtttgataga tttacaaaaa gattgtataa tagggataag aatagaaaag
     3661 gagaagtctc atggcagtta aagattttat gacccgcaag gtagtttata ttagtccaga
     3721 tacaacagta tctcatgcag cagatttgat gagagagcaa ggtttgcacc gtctgcctgt
     3781 tatcgaaaat gatcaattag ttggtttggt gactgaggga accattgcac aagcaagtcc
     3841 atctaaagca acaagtcttt ctatctatga gatgaattat cttctgaata agacaaaagt
     3901 aaaagatgtc atgattcgcg atgttgtcac tgtctcaggc tatgctagtc tagaagatgc
     3961 aacttatctg atgttgaaaa ataagattag tattctccct gtcgtagata accatcaagt
     4021 atacggagtt attactgacc gtgacgtttt ccaagccttt cttgaaattg caggttatgg
     4081 cgaagaaggg attcgtgtac gctttgttac agaagatgaa gttggtgttc ttggaaaaat
     4141 tgtttctttg attgtagaag aaaatttgaa tatctcccat acagtcaata ttccgcgtaa
     4201 ggatggtaag gtgattatcg aagtgcaaat cgatggatca attgatttac cagccttgaa
     4261 agaaaaattt gaagcaaatg gtattcaagt ggaagaaatc gctcgcactt cagcaaaagt
     4321 cttgtaagaa gggaagccca aaggcttctt ttttcatgaa aaggggatta gagcaaaaga
     4381 tggaaagaaa tgataaaata tgctataatg aaataatgta aaaaaggagt atttatggac
     4441 atttcagtaa ttcgtcagaa aattgacgca aatcgtgaaa aattagcttc tttcaggggg
     4501 tctctttgac ctcgaagggc tagaggaaga gattgccatc ttggaaaaca agatgacaga
     4561 acctgatttt tggaacgata atattgcggc ccaaaaaacg tcgcaagaat tgaatgaatt
     4621 aaaaaacact tacaatacct tccataagat ggaagagttg caggatgaag tcgaaatttt
     4681 attggatttt ttggctgaag acgagtcagt gcatgatgaa ctggtagcgc agttagccga
     4741 acttgataag ataatgacca gctacgagat gactctacta ttgtcagaac cttatgacca
     4801 caacaatgcc atcttggaaa tccatccagg ttctggtggt actgaggcgc aggactgggg
     4861 tgatatgttg cttcgtatgt atactcgtta tggtaatgct aaaggcttta aagtggaagt
     4921 gttggattac caagcaggtg atgaggctgg tattaagtcg gtaactttat catttgaagg
     4981 gcctaatgcc tatggtctcc tcaagtcaga aatgggtgtt catcgcttag tgcgaatctc
     5041 accatttgac tctgccaaac gtcgccatac ctctttcaca tctgtagaag tgatgccaga
     5101 attggatgat actattgaag tggaaatccg tgaagatgat atcaagatgg ataccttccg
     5161 ttcaggtggt gccggtggac aaaacgtcaa taaggtttca acaggtgtac gtttaaccca
     5221 cattccaact ggaattgttg tccaatcaac agtggatcgt acccagtatg gaaatagaga
     5281 tcgtgccatg aagatgttgc aggctaagct ctatcaaatg gagcaagata agaaggctgc
     5341 ggaggtagat tctctcaaag gtgagaaaaa ggagatcact tggggaagcc aaatccgttc
     5401 ttatgtcttc acgccttata ctatggtaaa agatcaccga actagctttg aggttgctca
     5461 ggtagataag gttatggatg gggacctaga tggttttatc gatgcttatc tcaagtggcg
     5521 aattagctaa gatagaaagg aactcacatg tcaattattg aaatgagaga tgtcgttaaa
     5581 aaatacgaca acggaacgac tgctctacgc ggtgtttcgg ttagcgttca accgggggaa
     5641 tttgcttaca tcgtaggacc ttcaggagca gggaagtcaa cttttattcg ttctctgtat
     5701 cgtgaagtaa aaatcgataa aggaagtcta tcagttgctg gttttaatct ggttaagatc
     5761 aaaaagaaag atgtcccgct tctacgtcgt agtgttgggg ttgtcttcca agattataaa
     5821 ttgttaccaa agaaaactgt ctatgaaaat attgcttacg ctatggaagt aatcggggaa
     5881 aatcgccgta atatcaaaag acgagtgatg gaagttttgg acttggttgg attgaagcat
     5941 aaggttcgtt ctttcccaaa tgaactctca ggtggggagc agcagcgaat tgcgattgcg
     6001 cgtgcaattg taaataatcc caaagtattg atagctgatg agccaacagg aaatctggat
     6061 ccggataatt catgggaaat tatgaatctc ttggaacgga ttaacctaca agggacaact
     6121 attttgatgg cgactcataa tagccagatt gtaaatacct tgcgccaccg tgtcattgcc
     6181 attgaaaatg gccgtgtcgt tcgtgacgaa tcaaaaggag agtatggata cgatgattag
     6241 tagatttttt cgccatttat ttgaagcctt aaaaagtttg aaacgaaatg gttggatgac
     6301 agtagctgct gtcagttcag tcatgattac tttgaccttg gtggcaatat ttgcatctgt
     6361 tattttcaat acagcgaaat tagctacaga tattgaaaat aatgtccgtg tagtagttta
     6421 tatccgaaag gatgtggaag ataatagtca gacaattgaa aaagaaggtc aaactgttac
     6481 aaataatgac taccacaagg tatatgattc tttgaagaac atgtctacgg ttaaaagtgt
     6541 taccttttca agtaaagaag aacaatatga aaaattaacc gagataatgg gagataactg
     6601 gaaaatcttt gaaggagatg ccaatcctct ctatgatgcc tatattgtag aggcaaacac
     6661 tccaaatgat gtaaaaacta tagccgaaga tgctaaaaaa attgaaggtg tctctgaggt
     6721 tcaagatggc ggtgccaata cagaaagact cttcaagtta gcttcattta tccgtgtttg
     6781 gggactaggg attgctgctt tgttaatttt tatcgcagtt ttcttgattt caaataccat
     6841 tcgtattacc attatttccc gcagtcgcga aattcaaatc atgcgcttgg ttggagctaa
     6901 aaacagttat atccgtggac cgttcttgtt agaaggagcc tttatcggtt tattgggagc
     6961 tatcgcacca tctgttttgg tctttattgt ttatcaaatt gtttaccaat ctgtcaacaa
     7021 atcgttggta gggcaaaatc tatccatgat tagtccagat ttatttagtc cgttgatgat
     7081 tgccctacta tttgtgattg gggttttcat tggttcattg ggatcaggaa tatccatgcg
     7141 ccgattcttg aagatttagg taaaatagct gcttttatga ggagattgta aaatctcctt
     7201 ttttgctaca agagtttttg aaaagagatg cgtagaagaa aagagcttcc aaagaagtcc
     7261 cccagagaag acttcttgat ggctaatttg aacttgaaat ttggcgcact agaaattttt
     7321 tagaaaaaag tgtaattttt ttataaaagc ctttacaaaa aaaattaaag tggtataatt
     7381 aaatcataga aggtgcaaac gttttcgtaa aacgtttgcc taaataaaaa taaaggagat
     7441 ttgaatgatg aaagatacat tcaaaaatgt cttgtctttc gaattttggc aaaaattcgg
     7501 taaggctttg atggtagtta tcgcggttat gccggctgct ggtttgatga tttcaatcgg
     7561 taagtctatc gtgatgatta acccaacctt tacaccactt gtcatcacag gtggaattct
     7621 tgagcaaatc ggttgggggg ttatcggtaa ccttcacatt ttgtttgccc tagccattgg
     7681 aggaagctgg gctaaagaac gtgctggtgg tgctttcgcc gctggtcttg ccttcatctt
     7741 gattaaccgt atcactggta caatttttgg tgtatcaggc gatatgttga aaaatccaga
     7801 tgctatggta actactttct ttggtggttc aatcaaagtt gctgattact ttatcagtgt
     7861 tcttgaagct ccagccttga acatgggggt attcgtaggg attatctcag gttttgtagg
     7921 ggcaactgct tacaacaaat actacaactt ccgtaaactt cctgatgcac tttcattctt
     7981 caacgggaaa cgtttcgtac catttgtagt tattcttcgt tcagcaatcg ctgcaattct
     8041 acttgctgct ttctggccag tagttcaaac aggtatcaat aacttcggta tctggattgc
     8101 caactcacaa gaaactgctc caattcttgc accattcttg tatggtactt tggaacgttt
     8161 gctcttgcca tttggtcttc accacatgtt gactatccca atgaactaca cagctcttgg
     8221 tggtacttat gacattttaa ctggtgcagc taaaggtact caagtattcg gtcaagaccc
     8281 actatggctt gcatgggtaa cagaccttgt aaaccttaaa ggtactgata ctagtcaata
     8341 tcaacacttg ttagatacag tacatccagc tcgtttcaaa gttggacaaa tgatcggttc
     8401 attcggtatc ttgatgggtg tgattgttgc tatctaccgt aatgttgatg ctgacaagaa
     8461 acataaatac aaaggtatga tgattgcaac agctcttgca acattcttga caggggttac
     8521 tgaaccaatc gaatacatgt tcatgttcat cgcaacacct atgtatcttg tttactcact
     8581 tgttcaaggt gctgccttcg ctatggctga cgtcgtaaac ctacgtatgc actcattcgg
     8641 ttcaatcgag ttcttgactc gtacacctat tgcaatcagt gctggtattg gtatggatat
     8701 cgttaacttc gtttgggtaa ctgttctctt tgctgtaatc atgtacttta tcgcaaactt
     8761 catgattcaa aaattcaact acgcaactcc agggcgcaac ggaaactacg aaactgctga
     8821 aggttcagaa gaaaccagca gcgaagtgaa agttgcagca ggctctcaag ctgtaaacat
     8881 tatcaacctt cttggtggac gtgtaaacat cgttgatgtt gatgcatgta tgactcgtct
     8941 tcgtgtaact gttaaagatg cagataaagt aggaaatgca gagcaatgga aagcagaagg
     9001 agctatgggt cttgtgatga aaggacaagg ggttcaagct atctacggtc caaaagctga
     9061 cattttgaaa tctgatatcc aagatatcct tgattcaggt gaaatcattc ctgaaactct
     9121 tccaagccaa atgactgaag cacaacaaaa cactgttcac ttcaaaaatc ttactgagga
     9181 agtttactca gtagcagacg gtcaagttgt tggtttggaa caagtaaagg atccagtatt
     9241 tgctcaaaaa atgatgggtg atggatttgc agtagaacct gcaaatggaa acattgtatc
     9301 tccagtttca ggtactgtgt caagcatctt cccaacaaaa catgcttttg gtattgtgac
     9361 ggaagcaggt cttgaagtat tggttcacat tggtttggac acagtaagtc ttgaaggtaa
     9421 accatttaca gttcatgttg ctgaaggaca aaaagttgca gcaggagatc tccttgtcac
     9481 agctgacttg gatgctatcc gtgcagcagg acgtgaaact tcaacagtag ttgtcttcac
     9541 aaatggtgat gcaattaaat cagttaaatt agaaaaaaca ggttctcttg cagctaaaac
     9601 agcagttgct aaagtagaat tgtaatatac ttgaggttgg aagctgtatt ccaacctctt
     9661 attttgggag aaaagaatga aatttttaac actcaatact cacagttgga tggagaaaga
     9721 agcagaggaa aaattccaga ttttgcttga agatattctt gaaaaggact atgatttgat
     9781 ttgtttccaa gaaatcaatc aggagatgac ctcgtcagag gtggaggtta atgaccttta
     9841 tcaagctttg ccagcagctg agcctattca ccaagaccat tatgttagac tcttggttga
     9901 aaagttgtta gagcaaggga aaaattacta ctggacctgg gcttataacc atatcggcta
     9961 tgaccgctac cacgaaggtg tggctatctt gtctaaaaca cctattgaag ccagagaaat
    10021 tttggtttca gatgtggatg atccaacaga ctatcatact cgccgtgttg ccctagctga
    10081 aactgtagtc gatggcaagg agctagcagt tgccagtgtt catctctctt ggtgggataa
    10141 aggttttcaa gaagaatggg cacgatttga ggctgtcttg aaaaaattga acaagccact
    10201 tttactagct ggagatttta acaacccagc aggtcaggaa ggttaccaag ctattttagc
    10261 tagtccatta ggcttacaag acgcatttga agttgctcaa gagaaaagtg gtagctatac
    10321 tgttccgcct gaaattgatg gctggaaagg gaacactgaa ccccttcgaa tcgattatgt
    10381 ctttactacc aaagagttag cggtggaaaa tttacatgtc gtatttgatg gtaacaagag
    10441 tccacaagtg agtgatcact atggcttgaa tgctatatta aactggaaat aataactgaa
    10501 aagaggttgg aactataaaa ttccagcctt ttcttactag agaagctact ggaaatagcc
    10561 taaataagtg agactactgt aatggaataa aatatggtat aattgataag atagatagaa
    10621 tcgaggatgt tatgtcattt acgaaatttc aatttaaaaa ctatattaga gaagccttga
    10681 aggagttaaa atttacaact ccaacagagg tgcaagacaa gttgattcct attgttttgg
    10741 caggtcgtga cctagtagga gaatcaaaaa caggttcagg taagactcat actttcttgt
    10801 taccgatttt tcagcaatta gatgaagcta gcgatagtgt acaagcagtg attactgcac
    10861 cgagtcgtga gttggctact caaatttacc aagtagcgcg tcagatttca gctcactcag
    10921 atgtcgaagt tcgtgtggtt aattatgtgg gtggtacgga taaggctcgc cagattgaga
    10981 aattggcaag caatcagcct catattgtta ttggaacacc aggccgtatc tacgacttgg
    11041 ttaaatctgg tgatttagct attcataaag ccaagacatt tgttgttgat gaagcagata
    11101 tgaccttgga tatgggattc ttggaaactg ttgataagat tgctgacagt cttccaaaag
    11161 acttgcaatt catggtcttc tcagcgacta tcccacaaaa actgcaacca ttcttgaaaa
    11221 aatacttatc aaatcctgtt atggagaaaa ttaagaccaa aacggttatt tctgacacca
    11281 ttgataattg gttgatttcg accaagggac atgataagaa tgctcaaatt taccagttga
    11341 ctcagtcgat gcagccgtat ttggcaatga tttttgttaa cactaaaacg cgtgctgatg
    11401 aattgcattc atatctgact gctcaaggct tgaaggttgc aaaaatccat ggcgatattg
    11461 cccctcgtga acgcaagcga atcatgaatc aggtgcaaaa tctggatttt gagtatattg
    11521 tcgcaacaga tttggcagca cgtgggattg acattgaagg tgtcagccat gtcatcaatg
    11581 atgccattcc gcaagactta tctttttttg ttcaccgtgt tggtcgtact ggacgaaatg
    11641 gcctaccagg tacagctatt accctttatc agccaagtga tgactcggat atccgtgagt
    11701 tggagaaatt gggaatcaag tttagtccta agatggtcaa agacggggaa tttcaagata
    11761 cctatgaccg tgatcgtcgt gccaaccgtg agaaaaaaca agataaactt gatatcgaaa
    11821 tgattggttt ggttaaaaag aaaaagaaaa aagtcaaacc gggttataag aagaaaattc
    11881 aatgggcggt tgatgaaaag cgccgtaaaa ccaagcgtgc tgaaaatcgc gctcgcggtc
    11941 gtgcagagcg taaagctaaa cgccaaacat tttaatagaa attgttggag tactgagctc
    12001 caactttttt atttatgaga acgaactatc taaaccgaaa cactacatta aagactgcaa
    12061 attgcgatta aaaatggtat aatgataaag ttatatagtc ccgataagat ggtaggtatt
    12121 tattacgaag agttttccta tcagtagttt gcaattcgca aagaatgacg gcttcgaggt
    12181 cgctcgtctt tctacggttg ccgccatact gcggtcaccc tatgcgcctt actagcttca
    12241 gaaataaaaa agtatcgttt ttatttctga agctagtaac tcttagataa tggaaattcc
    12301 tatcagtact ttgtaactct ataacaatat tttttaaggg gggacatttt tatgtcagaa
    12361 cgtaaattat tcacgtctga atctgtatct gaggggcatc cggataagat tgcagaccaa
    12421 atttcagatg cgattttgga tgctatttta gcaaaggatc cagaggcgca cgttgctgct
    12481 gaaacagctg tatatactgg ttctgtccac gtttttggtg aaatttctac aaatgcctat
    12541 gtggatatta accgtgtggt tcgtgatacc attgcagaga ttggttatac caatacagaa
    12601 tatggatttt ctgctgagac ggtgggagta cacccatctt tggtggaaca atctcctgac
    12661 atcgctcaag gtgttaacga agccttggag gttcgtggaa atgctgatca agatccactg
    12721 gacttgattg gagcaggtga ccaagggctc atgtttggat ttgcagtaga tgaaacagaa
    12781 gagctcatgc cattgccaat tgcactcagt cataaattgg ttcgtcgtct ggcagaactt
    12841 cgtaagtctg gagaaattag ctatctccgt ccagatgcaa aatcacaagt tacagttgag
    12901 tacgatgaaa atgaccgtcc ggtacgtgta gatacagtcg ttatttctac tcagcatgat
    12961 ccagaggcca ctaatgaaca aatccatcaa gatgtgattg acaaggtcat caaagaagtt
    13021 attccatctt cttatcttga tgataaggca aaattcttta tcaatccgac aggtcgtttt
    13081 gtaatcggtg gtcctcaagg ggactcaggt ttgactggtc gtaagattat tgtagatact
    13141 tatggtggct actctcgtca tggtggtggt gccttctctg gtaaagatgc gactaaggtg
    13201 gatcgttcag cctcttatgc ggctcgctat attgccaaga atatcgttgc agcaggcctt
    13261 gctaagaagg cagaagtgca gttggcctat gctatcggtg ttgcgcaacc tgtttctgtt
    13321 cgtatcgata ctttcggtac aggaacagta gctgaaagtc aacttgaaaa agcggctcgt
    13381 caaatctttg accttcgccc tgcagggatt atccaaatgc tggacctcaa gcgtccaatt
    13441 taccgtcaaa catcggctta cggtcacatg ggacgtacag atattgatct tccatgggaa
    13501 cgtttggata aggtagatgc tttgaaagaa gcagtaaaat aagattttaa gaggggaacg
    13561 tcctctcttt tttatagttt ttaactatac tgggatactg ttctgaaaat ccattttgcg
    13621 aaagtagaga tttacatgta taatggattg aaactagaat agtacacctc aacttctaaa
    13681 acattgttag aaatcgattt gactgtcctg atcgatttct cctgttcttg tttcatttta
    13741 ctatatttct ttaaaaatga taaaggttga gatttctcct cgtaatagat aatcatgggg
    13801 atatttcaag ccaaagtttt attcgttatc acttgactat tgcaaggttt tctagatcaa
    13861 cagagtcatg gaatggactc atggttgaga tttctccttg ttgcttggac ttcattcaaa
    13921 agtctgttac ccaagccttg ttcaaacttc caatacacta gctgtttcca tagcatgact
    13981 tctgtactag actttctttt ccgaataaat agatagaacc acagaatcta gtaaacctag
    14041 aattaaaatt atggtataat attagcaata aaagaaatct ggaggattag aatcatggta
    14101 tcaacgaaaa cacaaattgc tggttttgag tttgacaatt gcttgatgaa tgcagcaggt
    14161 gtggcttgta tgacgataga ggagttagaa gaggtcaaaa actcagcggc aggaaccttt
    14221 gttactaaga cagcgacctt ggacttccgt caggggaatc ctgagccacg ctaccaagat
    14281 gttccacttg gttccatcaa ctctatgggc ttgccaaata atggcttaga ctattatttg
    14341 gattatcttt tagatttgca ggaaaaagag tcgaaccgaa ctttcttctt atctctggtc
    14401 ggcatgtctc cagaggaaac ccatactatt ttgaaaaaag tccaagagag tgattttcgt
    14461 ggtctgactg agctaaatct ttcctgtcca aatgttccag gtaaacctca gattgcctat
    14521 gattttgaga caacagaccg gattttggca gaagtgtttg cttacttcac caaacctctt
    14581 ggaattaaat tgccacctta ttttgatatt gttcactttg atcaagcggc agctattttc
    14641 aacaaatatc cgctcaagtt tgtcaactgc gttaactcta tcggaaacgg cctctatata
    14701 gaagacgaat ctgtcgttat tcggcctaag aatggttttg gtggaattgg tggagaatac
    14761 atcaaaccga ctgctctagc caatgttcac gccttttatc aacgtttaaa tcctcaaatc
    14821 caaattatcg gaacaggtgg cgttctgact ggtcgagatg cctttgaaca catcctctgt
    14881 ggagcaagta tggtgcaggt gggaacgacc cttcacaaag aaggcgtcag tgcttttgac
    14941 cgcattacca atgaactgaa agcaatcatg gtggaaaaag gctacgagag cttagaagat
    15001 ttccgtggga aattgcgcta tattgactaa attaaatcaa aaaatctgaa gaaaggagag
    15061 acgatgctag ccattgaaga aagtcagaag ttgactttat caaatttacc gagcctgagc
    15121 ctatttacag ggacagatca gggtcagttt gaagtgatga agagtcaaat gttgaaacag
    15181 attgggtatg attctgctga cctcaacttt gcctactttg atatgaaaga agtagtttac
    15241 aaggatgtgg aactggagtt ggtcagcctt cctttctttg cggatgagaa aatcgtgata
    15301 ttagattatt ttatggatat cacgactgct aagaaacgct ttttgacaga tgatgagctt
    15361 aagtcatttg aggaatacct tgacaatcct tctccaacaa ccaagttgat aatctttgca
    15421 gaaggaaagc tggatagcaa aagacggtta gtcaaattac ttaagcgtga tgccaaggtc
    15481 ttcgatgcag tagaagtaaa agaacaagaa ttgcgccagt atttccaaaa gtggagtcag
    15541 aaacaaggtc tgcagtttac caatcattct tttgaaaatc tcctcatcaa gtcggggttt
    15601 caatttagcg aaatccagaa aaatcttctc tttttacagt cctataaggc gaattctgtt
    15661 attgaggaag aggatattgt taacgcaatt cccaagacct tgcaggacaa tatttttgat
    15721 ttaactcagt ttattctgac taaaaagatg gatcaggcgc gcgatttggt gagagacttg
    15781 accttgcaag gggaagatga aatcaaactg attgcagtca tgctgggaca atttcggact
    15841 tttactcagg tgaagatttt ggcggagtct ggccaaacag aatcgcagat tgcaagtagt
    15901 ttaggtagtt atctgggacg taacccaaat ccttatcaaa tcaagtttgc attaagagat
    15961 tcgagaggac tttctttgag ctttctgaag caagctattt cctatttgat tgagacagac
    16021 tatcagatta agacaggtct ttatgaaaaa ggtttccttt ttgaaaaggc actcttacag
    16081 attgctagtc aggtcaattg acatttgttg aaactacaac ccgcgtcagg attatcttgt
    16141 cgtgggtttc ttgctgattt gcttatttta ttagaaagta tgtcagtgat ttccttatct
    16201 ataagcaaaa aacttgaaaa aagtgaatgt ttgcgttatc attttcatat agaaagaaaa
    16261 agaggtatta cagatggcta ttatcttacc agaacttcca tatgcatacg acgctttgga
    16321 accatacatc gatgcggaaa caatgcattt gcaccatgac aaacaccatc aaacttatgt
    16381 caacaatgcc aatgcagctt tagaaaaaca ccctgaaatc ggtgaagacc ttgaagcctt
    16441 gcttgctgat gtagaatcta tcccagctga tatccgtcaa gcacttatca acaatggtgg
    16501 cggacacttg aaccacgctc ttttctggga attgatgact cccgagaaaa cagctccttc
    16561 agcagaactg gcagcagcaa tcgatgcaac atttggttca tttgaagaat tccaagcagc
    16621 cttcactgca gcagcaacaa ctcgttttgg ttcaggttgg gcatggttgg ttgtcaacaa
    16681 agaagggaaa cttgaagtga cttcaacagc aaaccaagac acaccaatct cagaaggtaa
    16741 aaaaccaatc ttgggcttgg acgtttggga acatgcttac tacgtgaaat accgcaacgt
    16801 gcgtcctgac tacatcaaag ctttcttttc agtaatcaac tggaataaag tagatgaatt
    16861 gtacgcagct gctaaataat gatagttgga gggaagaatt gttcttctct ttttaggtta
    16921 taagattctg gtctgacaaa atcgtcagac ttttttcatt tttatgagaa acgtgctaac
    16981 tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat atctatgcga
    17041 aaagaaattg cacctgaatt atacaactat aacaagtttc ctggtccgga gttccattta
    17101 cacggggata aggtcgaaac ggaagggata gctttttcct tggttgaaaa tatcaaggat
    17161 gcctttgatg tgacgacttt taatcagcgt ttttcagaag tcttaaccaa gtttgattat
    17221 atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa ggatgaccga
    17281 acagaagaaa aacttgaaaa aatcagtcgt ttacaagact accttttaga gtattgtagt
    17341 tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc atttgacaag
    17401 aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc gactcaaact
    17461 aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca gcattctcag
    17521 aaagaggaca aggaacaacg tcattttgtc attcgtcaga agtgagtaga gaataaggag
    17581 aagaaatgaa accctcaatt catagtttga cacatcaaac catgcaggaa tgggtattgg
    17641 agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac cgtaaacgtg
    17701 tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag ctcaatgacc
    17761 agtttgtggt caatcccttg aaacaaggta ttgtgcaaga gtctgctgat ggtacagtca
    17821 aatatctctt tgaattgcct gacggtatgt taattgagac tgtactcatg tgtcaacact
    17881 atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt accttctgtg
    17941 cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta gcgcaaatca
    18001 tgctggttca gaaatacttt gatgagcgtg gtcaggatga acgcatcagc catatcgttg
    18061 tcatgggaat cggtgagccc tttgataatt acaacaatgt cttgaatttc tttcgtacta
    18121 tcaatgatga taaaggaatg gctatcggtg ctcgtcacat cacggtttca atctcaggtt
    18181 tggctcataa aattcgtgac tttgctgatg aaggggttca ggtcaatctt gccgtgtctc
    18241 ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa gattaaccgt gcctttccga
    18301 ttgaaaaact ctttgctgct attgaatact acattgagac aacaaaccgt cgtgtaacct
    18361 ttgaatatat catgcttaat gaagtcaacg acggtgtgga acaagccttg gaattggctg
    18421 aattgctcaa gaacatcaag aaatcgtctt atgtaaactt gattccttat aacccagtta
    18481 gtgagcatga ccaatatagc cgtagtccca aagagcgcgt gttggctttc tatgatacgc
    18541 ttaagaaaaa agggggcaac tgtgtggttc gtcaagagca tggtacagat attgacgcag
    18601 cttgtggaca attgctcttt aacacaatga aacgtgaccg ccagaaggca gtcgcagcgg
    18661 taaatcctta atgatgaaga agacttataa tcatattttg gtctggggag tcattttcta
    18721 tagcatttgc attgtctatt tttgctttac tcctcaagaa caatctaccg tgggagtggg
    18781 aactccagat attcagcatc ttggacgcct ggtttttctt ttgactcctt tcaattctct
    18841 ctggaaactg ggcgaagtga gtgacattgg acaattatgt tggatttttt tacaaaatat
    18901 cctcaatgtc ttcttgtttt ttcctctgat tttccaactc ctttatctat ttccaaattt
    18961 gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg agtcttggaa tcgagtgtac
    19021 gcaattaatc ttggactttt tctttgattt caatcgcgtc tttgagattg atgatttgtg
    19081 gaccaacact ttgggtggct atctggcttg gctcctttat aaacgattac ataaaaacaa
    19141 gataaggaat taaaatgagt attttagaag ttaaaaatct gagtcacggt tttggtgacc
    19201 gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg ggaacatatc ggcctggtcg
    19261 gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt gactggtaaa atgctgccag
    19321 atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg ttacttggat cagcactctg
    19381 tccttgctga aagacagtcg gtgcgtgatg ttctccgtac ggcttttgat gagcttttca
    19441 aagctgaagc tcgtatcaat gacctctata tggaaatggc tgaagacggt gcggatgttg
    19501 atgctctcat ggaagaagta ggagaacttc aagaccgtct ggagagtcgt gatttctata
    19561 ccttggatgc taagattgac gaagtagcgc gtgctcttgg tgttatggac tttggcatgg
    19621 atacggatgt aacttctttg tcaggtgggc aaagaaccaa ggtgcttttg gcaaaacttc
    19681 tccttgaaaa gcctgatatc ttgctgttgg acgagccgac caactacttg gatgctgagc
    19741 atattgattg gctcaagcgc tatctccaaa actatgagaa tgcctttgtt ctcatttcgc
    19801 acgatattcc attcctcaat gacgttatca atattgtcta tcatgtggaa aatcaacagc
    19861 tgacgcgtta ctctggtgac tactaccagt tccaagaagt ttatgctatg aagaaatctc
    19921 agctagaggc agcctacgaa cgccagcaga aagagattgc agacctcaag gactttgtgg
    19981 ctcgtaataa agcccgtgtt gcaactcgta atatggctat gtctcgtcaa aagaaattgg
    20041 ataagatgga tattatcgaa ctccaaagtg agaaaccaaa accatccttt gatttcaaac
    20101 cagctcgtac accagggcgc tttatcttcc aaaccaagaa cttgcaaatt ggttacgacc
    20161 ttcctcttac taagccttta aatcttacct tcgaacgcaa tcaaaaggtt gcgattattg
    20221 gtgctaatgg tattggaaaa acaactctct tgaagagtct cttgggcatt atctcgccaa
    20281 tcgctgggga agtggagcgt ggagattatt tagaacttgg ttattttgag caggaagtag
    20341 aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa tgcctttcct gcccttaatc
    20401 aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac aaccaaacat attgaaagcc
    20461 agattcaagt attatcaggg ggagagcaag ccaaggttcg tttctgtctc ttgatgaatc
    20521 gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca tttggatgtg gatgcaaagg
    20581 atgagctcaa acgcgctctc aaagaatata ggggatctat ccttatggtc tgccacgagc
    20641 cagactttta tgaaggctgg atagaccaaa tatgggattt taataattta acttaagaat
    20701 gagagtaaaa gaaatacagt accgaatgtg gatactgtat ttttttggtt tttaagattt
    20761 aaaatcgtag tctttcacca cttcgatgct gtcgattgtg atagcagtag ttggcttgtc
    20821 tttttcatct ttttcggcct tagcaatctt atccacaaca tccataccgt caatcacttg
    20881 accaaagact gggtgtttgc catctagact agggtttcca ccttctttgt aggcttcgat
    20941 aattttctgt ggatacttgc ttgtagggag tttagaagag gtatctgtag agctttggtt
    21001 gatgaagaac tggctgccat tggtgtttgg ttgaccagta ttagccatag caagagcacc
    21061 acggatgtta tacaaataag gagtaatctc gttcttgaaa ccagttcctt tgtctttagt
    21121 cttatccttg tcatgccaga tggactgacc acctgtaccg tccccttttg gatctccagt
    21181 ttggaccata aagccatcga tgacacggtg gaaggtaata ccgttatagt agccttcttt
    21241 ggcgtgagtg aggaaatttt caaccgctag aggagcgagt ttagggaaga gtttaatgcg
    21301 aatatcacct tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa cttccttaga
    21361 tagttgtggg aaattggcgt tttcgtttgt taaagcatcg tttaactcct tggcagattg
    21421 ggcagctact ttggaacttt cttcagcagc aagactggaa tcaacataat catcaccacg
    21481 cagactgcgt tggacgctgc tacacccagc tagggctaca gtagacagta aaagaagggt
    21541 tgctagtttt ttcattctga tcctctcaaa aattcattta taccattgta ccctaaaaag
    21601 aagtggattt caaatattag tagtttacag aactggctta gataatagtt gggatttcat
    21661 catcatcttg aaaatcttca acttcttcaa cttcttcccc agtaaatggt ttctgaaaag
    21721 aacttagtat aaaacgggca attggttcaa caattaggaa atttagagga agagctgcaa
    21781 taaagtttac gaaccaggcg cttagatagg tattgggtgt gatagcaatg ccattgtaaa
    21841 aaagtccata gaaggacatg aaagtgacca gctaattctt cttctgaaaa atgctcatga
    21901 agggcttgat ccaggtcgca agatttcatt ttagaaagtc cagtaactcc cttcttcttc
    21961 aggatattct ttttcatggt attatttaga tggtcaagtg agtcaaaaga agtttcgaca
    22021 agagcatacc ctttttctat cagagttttt agatgtttag gggcatcaat accataagtg
    22081 tactcaaagt attttggaaa ccagatctta agaaagctcg taaagctagc cagttctcta
    22141 aacgctaaga actagctaca acacagcatt tacaacactt catggttcac accatggggt
    22201 gctttttaat gattttaagc aaaattcaca cttaattgaa agttatttaa attagatgaa
    22261 aatttatttt ttgaaaaagc gggaaaacat tgattctaag cgaattttga atcatattcg
    22321 aatgggagtt tttaaaatca tgtttcagtg gtaaaagtac caaactggat tctccatagt
    22381 aaaatgatat ctcctgctag tgaatcatct actaataagt ccatatttcg cttgggaacg
    22441 ggcttgggac ttagaagcca agtatccaac tctcgttcag gcgatatgaa gggtttgact
    22501 tggtgttctt tataaaattt ttctaaaata gtattcacgg atagcatctt tcaaacattt
    22561 atttcctatt ctaacaaatt tctaaatact ttaagaaatt tatagtctgt caagtttttt
    22621 tcttgacaca tgccagaaat ctgctataat agaacatgtg ctaaatagct cagctatttc
    22681 accgaaataa aaaattaaag aaatgagact ttaaaaatgg cagttaaaat ccgtttgact
    22741 cgtatgggtt ctaagaaaaa acctttctac cgtatcaacg tagcagattc acgttcacca
    22801 cgtgacggac gtttcatcga aacagttgga acttacaacc cacttgttgc tgaaaaccaa
    22861 gtaactttga aagaagaccg cgttcttgca tggttggcta atggagctca accttcagac
    22921 acagtacgta acatcctttc aaaagaaggc gtattgaaaa aattccacga ttctaaattc
    22981 tcaaaataag tttaaagtag gttgacagat ggatacgatt gaaaatctca ttattgcgat
    23041 tgtgaaaccc ttaatttcac aaccagatgc cttaactatc aagattgagg atacaccaga
    23101 atttttggaa tatcatttga atcttgatca aagcgatgtg ggtcgtgtaa tcggtcgtaa
    23161 gggtcgcact atttctgcga taagaacgat tgtctactct gtcccaactg aatacaaaaa
    23221 agtaagaatc gttattgacg aaaaataaga agggcgggac ggatgtctcg cttttttgtg
    23281 tggaatagaa g
//
LOCUS       DAVBNN010000028        22797 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBNN010000028 DAVBNN010000000
VERSION     DAVBNN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.028"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(112..909)
                     /locus_tag="VQ847_001191"
     CDS             complement(112..909)
                     /locus_tag="VQ847_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3050536.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(899..2743)
                     /gene="uvrC"
                     /locus_tag="VQ847_001192"
     CDS             complement(899..2743)
                     /gene="uvrC"
                     /locus_tag="VQ847_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3050537.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(2783..3484)
                     /locus_tag="VQ847_001193"
     CDS             complement(2783..3484)
                     /locus_tag="VQ847_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3050538.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(3563..4795)
                     /gene="murN"
                     /locus_tag="VQ847_001194"
     CDS             complement(3563..4795)
                     /gene="murN"
                     /locus_tag="VQ847_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3050539.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(4800..6020)
                     /gene="murM"
                     /locus_tag="VQ847_001195"
     CDS             complement(4800..6020)
                     /gene="murM"
                     /locus_tag="VQ847_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3050540.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(6132..6911)
                     /locus_tag="VQ847_001196"
     CDS             complement(6132..6911)
                     /locus_tag="VQ847_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3050541.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(6980..8641)
                     /locus_tag="VQ847_001197"
     CDS             complement(6980..8641)
                     /locus_tag="VQ847_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3050542.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(8816..11038)
                     /gene="recJ"
                     /locus_tag="VQ847_001198"
     CDS             complement(8816..11038)
                     /gene="recJ"
                     /locus_tag="VQ847_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3050543.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            11315..12073
                     /locus_tag="VQ847_001199"
     CDS             11315..12073
                     /locus_tag="VQ847_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3050544.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            12084..12878
                     /locus_tag="VQ847_001200"
     CDS             12084..12878
                     /locus_tag="VQ847_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3050545.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            12891..13568
                     /locus_tag="VQ847_001201"
     CDS             12891..13568
                     /locus_tag="VQ847_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3050546.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            13578..14237
                     /locus_tag="VQ847_001202"
     CDS             13578..14237
                     /locus_tag="VQ847_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3050547.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            14474..15598
                     /locus_tag="VQ847_001203"
     CDS             14474..15598
                     /locus_tag="VQ847_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3050548.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(15996..16877)
                     /locus_tag="VQ847_001204"
     CDS             complement(15996..16877)
                     /locus_tag="VQ847_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3050549.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(17018..18346)
                     /gene="vncS"
                     /locus_tag="VQ847_001205"
     CDS             complement(17018..18346)
                     /gene="vncS"
                     /locus_tag="VQ847_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3050550.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(18343..18999)
                     /gene="vncR"
                     /locus_tag="VQ847_001206"
     CDS             complement(18343..18999)
                     /gene="vncR"
                     /locus_tag="VQ847_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3050551.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(19048..19131)
                     /gene="pep27"
                     /locus_tag="VQ847_001207"
     CDS             complement(19048..19131)
                     /gene="pep27"
                     /locus_tag="VQ847_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3050552.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(19312..20691)
                     /gene="vex3"
                     /locus_tag="VQ847_001208"
     CDS             complement(19312..20691)
                     /gene="vex3"
                     /locus_tag="VQ847_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3050553.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(20743..21390)
                     /gene="vex2"
                     /locus_tag="VQ847_001209"
     CDS             complement(20743..21390)
                     /gene="vex2"
                     /locus_tag="VQ847_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3050554.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(21403..22680)
                     /locus_tag="VQ847_001210"
     CDS             complement(21403..22680)
                     /locus_tag="VQ847_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050555.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         6469 a         5274 c         4141 g         6913 t
ORIGIN      
        1 acggctagct tcctagtttg ctctttgatt ttcattgagt ataagatata ctaaaagcga
       61 ttggaccagc caatcgcttt tttagtttgc attggctatt ttaggaaact cttacaaaaa
      121 atcaaaaaaa ttcttcacat cctctacata cccatgcttt tctattaagc tggctaataa
      181 ttccagattg tgcccctgat agttatcgtc acgacgcagt tcttcataca tttcgataaa
      241 gggaagcccc ttggacttgg ccaattctaa ctcagcttcg taatcataag caactttacg
      301 aaattggata ttgagtaatt ccccatcttc aacttctatc acggcatact gggcacggtg
      361 attttttaac gcctcccaat taaaataggg catgccaatc gaccctggat tgatgatttg
      421 ttgcccttga cttccataac gaagcaactg cttgtgaaca tgaccataaa ctgccacgtc
      481 cgtttccgca tctagcaagt caccaccata gtttttgtca ggtaaattat gagagataga
      541 aaagcgcaat ccgtcaattt ctttcttttc cagcaaaggc aagcttcgta gccagacaat
      601 cgttgcagga tccattcgct ccatcaaata ctgtgtcata cgcaagagct gaacttcctg
      661 tgggtcttct aagccatatt gcccatctaa agcctcaagg acacgatcat cccaattgcc
      721 tcgaacactt gctgtgatag gaaggtcctt tagcagggcg actaagtcat ttgcgcctgg
      781 accaggaaga aaaatatctc ccagaagcca atattcactg gccccttgat ttttagcatc
      841 tgcaatcact gcttctagcg ccgtcgcatt gccatgaaca tctgataaaa ttgcgatttt
      901 atggttcatt gtggtttcct tccgtttggt aatctactct ttcttctgct acttgaggca
      961 aggcttctcc ctgcgggttc aactttcttt gcacagcctc tgcaacgact ctaggtaccc
     1021 caacttcgac aatctcatcc acactggctt ccttgatttt ggtcaaagac ttgaaatgcc
     1081 tcatgagatt ttgcttgcgt ttaggtccca gaccatcaat cccatccaat tgagatgaga
     1141 aagaattttt ggagcgcagt tggcggtgga aagtgatagc aaagcggtgc acctcatctt
     1201 ggatgcgttg gaggaggaaa aattcctgag aattgcgaga caagtccacc acctcaagcg
     1261 gatctccaaa gagcaattca tgggtttggt gcttatcatt cttttgcagc ccagcaattg
     1321 gaatatccaa gcccagttcc tcttggataa cctgcttagc gatattgact tgaccttgcc
     1381 ccccatcaat cacaatcaaa tctggaggag tcaaagcctc acgctgtact cgaccatagc
     1441 gtctgcgaat gacctctctc atgctggcat agtcgtctgg tccaacaacc gtttttatct
     1501 tgtacttacg gtaatccttc ttactcggtt taccgttgac aaagaccacc atagccgaaa
     1561 cagggctagt tcccatgata ttagagttat cgaaggactc gatacgtact ggggtcggga
     1621 tttggagcaa acgccctaga ttttcaatag ctccttgagt cttttcgaca gatttttcta
     1681 gcagattgaa cttctgctct agactaacac gagcattttt tatggctaga ttgaccagtt
     1741 gttttttctc tccacgttga ggcttaagaa tcttggaatc caccaaggcc ttgacagcct
     1801 cttcgtcaat atcctgcgga atcagtacct cattgggaac tagatgagat ttttcttgat
     1861 agaattgtcc tacataggtc aaaaaatcct catctggatc attgaagtag gggaagagat
     1921 tgacatcgcg ctcgataagc ttaccctgac ggacaaagaa aacctgcaca cacatccagc
     1981 ccttatccac atagtagcca aagacatcgc gattttgcaa atctttcgcc atgacccgtt
     2041 gcttggttcg aagcgttcca atagcctgaa tcaggtcacg gtattccgcc gcacgttcaa
     2101 actccatact ttgtgctgct actgccattt tactcttgag atcatcgatg attttgtcat
     2161 cctgaccttt cagaaaatca gacacctcct gagccataga cttgaaataa gcctcatcct
     2221 tcttacagat ggtgtgggcc atacactggc cgatatggta ataaaaacag accttagagg
     2281 gcgggttggt acattttcga aaagggaaaa tcctatctag aagtcgcttg atttcattgg
     2341 ctgcccccac atctggataa gggccaaaat aaagaccacc gtcctttttg acctgacgag
     2401 taatgataag ccgtggatag cgctcattgg tgattttgat gaaaggatag gacttgtcat
     2461 ccttgagcat gatattgtac ttgggcttgt tttccttgat caggttgatt tctaggagaa
     2521 gtgcctcaat attagactcc gtaacaataa attcaaaatc cacaatttca gacaccagag
     2581 cctctgtctt ggtatcatga cttccacgaa aataggaccg tactcgatta cgcagatttt
     2641 tagcctttcc tacatagata atggtgccat ttttatcctt atgaatgtag caaccagggc
     2701 tggtcggcaa gagctctagt tttgatttaa tcaagttgtt catagttcca ttatagcaaa
     2761 aaaagtaggg aaagatagta ccctactcac tagtctcata tatttttcgg aggtttgcaa
     2821 catcctcttc ctggatacca taaaaggaac ctgctggttg catgacagac ttctcatctg
     2881 tatggtccaa gccaatcgca tgacctaact catgttctgc cgtatggaca aggcgttcat
     2941 aggagtagcc atagtatgga ttggacaaat aataatgatt caaccgcacc gttacggaca
     3001 agaattgccc tgttaagaga ttagtttgac tttccgcctc tcctgccaca ggagtgcctc
     3061 cgtcgttcat ctccgtagcc gtaatatccg ccttactaga ctcagtcacg agttcaaagt
     3121 taaaagcacc agtttgattc cagttctgga ttgcttctaa ataagcctct tgaaagcgtg
     3181 aatccatctg cggatccagg taaatacgag cagaggcctg tgcccacctt ccttcagaat
     3241 gctggtgact atctgtctgg cttaacttag gcagttgccc tgttttctcc cattggtcaa
     3301 tactttgttg accaattttt actgaccgtt ctgcttgctt tagcgctcct tgaaaatccc
     3361 cgttcagata ccagagaagt ccgaaagcaa gcacacataa gagcacaact atccaaacca
     3421 gacgccaaaa caaacgccac acaaaagaaa agaaagcccc tatcaaacga aaaagccagc
     3481 gcatgtctct ccacctttct agcaaataag aattatttta ctaaaagaag ctaaaagaaa
     3541 tctaaatact gactttttca tcttaacgtc ctactatttt tttgagtaac tggatagctt
     3601 tgtattttaa aggcgatgga tggtaacgga aagtacccgc tttgcgtaca atatagccat
     3661 taaaattctg tttaaaacgc aaaacaccat cacttccatc aaaaatccct tgaatgccta
     3721 ggaagttgta tttaggtatt ccacgtttta tgctttccaa cataacatat ttttgaagca
     3781 gggcaggggc atagaactta ttaaactcag tgtaggaacc actaaagaga taagtcgttt
     3841 cctgaggcat ataaacaaat aaactcccag ctaaaacaat atcttcttct ccatattttt
     3901 caatcaagtc tcgcgcttct gcttttcgaa cttcaaacgt ttcaaattga ctagaatatt
     3961 ctctcagttg attttgtttt ttctcagaat gaggattttt actcaaatca agtcgcaact
     4021 tgtccaagtt ttcttctagt ttactttgtt caccttgcaa tttgctcata tagtccgaaa
     4081 aatttaagct tgctatgaga aactccgctt gttctccaaa agtatcataa aaatgctcat
     4141 aatattctaa acttttatca ctatattctc tacgttcaga ggtttctttt gttatattct
     4201 taaaaatcga tagttcttca cgttttaact ttttcaaccg aatgccaaag gtttcagcct
     4261 ttttcaccaa gggtttaccc tttttgctaa aacttttaag caaactcttt tcagttaatt
     4321 cagttaaatc tttatagtat aaccaatctg gttctccacc tgggtaacct gttgttaagc
     4381 catcaaattg ataacctaaa tcagtcaaac cttgaataat actttttttc tcagcatcta
     4441 ttggattacc ttggctatca aaagtttgat aagtttcata aggttttaca agcaactcta
     4501 atacaccatt ttgcttggca tattctttta actctgcata aaaaactgga agagcatctt
     4561 gttgggtata aatcggcccc gaattgagtt ccatatgcag accacccagc atgggcaagc
     4621 tataaaccag agctgcaact tgaatttctc cttcttgttt caaagcaaga taaacaattc
     4681 gagcccctct tttttctagc aaatccccca tctggacaga ttgcataaag gaacgagaag
     4741 aaacctgatc agaataagtc tgaaactctt ctttcgtgag tgttgttagt gccatatact
     4801 tactttctat gtttttttct taatgtttta cggaaatcaa gagcaagtct taacagagga
     4861 tagagaggat gagtgggcat tgtaaattca cccaagtatt cttcaatcgt tggattaaat
     4921 ttttccttaa aatgataaag tccaccattg agagagtttt caacaccacc taaattttgc
     4981 caaaccatac ctcgctcaaa ggcatagcga gccgtttcat accatgttaa aattggtgca
     5041 ttgtaacgtt taaaatcatc atccatacca gcatatatat tgacagaggt agtaccaaat
     5101 tccaaactca aagtagccgc taaaggaact ctcgcttgac ctacatctat atattcctgc
     5161 aagaaggtca attcctctaa caaacgttct ttttccttct tctgcgcttc tacttttgaa
     5221 attcgagtcg actcagtaaa ggtctcttcc aaggctctat tttttgctaa ctgttcttct
     5281 aattcttgcg aacgtttaga aacatccaag gtggccaagg tgatataggc cttgtcctta
     5341 aaattatcta acaatttttt ataataggct tcattcctca aatgaatctc ttttcgcttc
     5401 tcagtttttt tcatcaactc cgaaaatgaa tctaatagtt ccagtccacc atattgaatc
     5461 tcaagccctt tgtttcgtgc tgttcgaata gcctgttttg ttgacttgga aagtttatct
     5521 tcttcaaaat tttccttgta tattttcgcc tgaatacgag gttgaatggt gtctcccatt
     5581 tcctccgttt ttcctgacca ccttactccc atttgttgca aactatcaat aatagccaga
     5641 ttttcaggaa attctgtctt ttcctgattg attaaacttt gagataggca aatacttggg
     5701 tcaaaagtca caaaaaccgc tctcttactg cgagcatagg acttaataga ctgaatgaca
     5761 aaattcaaga gttctttatc cccataatcc aatataggtc ctcttgggat gtaaaacatt
     5821 ttatagccta gcggaagagt tctaatcaaa atactagctg tcgccagtaa tttttcttcc
     5881 ctgtaaacac caaacttctc atgttgccaa ttagacttaa cttcctccca agcactactt
     5941 tgtaatacat tggctaattc atgttctttg acaaactgat catattctaa tgtgggaatg
     6001 ccaatttgat aacggtacat ttcctactct ctttcctcca gtattttatt actattctac
     6061 tactttcgtt tgaaaagtct agtgaaaaca tattttattt tagttctact ccccctatgc
     6121 tgaagttcaa actaagtcag tctctcttct aatttgaaat caattggtag ggttgttaaa
     6181 aaaacttcca attgtttttc ccagtagtac cactcgtgag ttccagcgct atggctatag
     6241 gtcacatcaa aacctagttt tttgagattt ttcactgcga gattattggc ttcgtacaag
     6301 aaatcctgtt cgccacacca cgcccaaagt ttggtctttt tatccgattt tttagccaga
     6361 ctttcaagag aatagggact agttgtccag tctttaatct ctccaaaaac acctctccag
     6421 taggctggac ttcccagatt ttgactttca ggagaaaagt tttgaaaact gagggcacct
     6481 gaaaagctag ctgcatgaga aaaacgattt gtcgcaagag ccagtttgaa gcagccgtag
     6541 cctcccatag aaagaccagc gataaaggtc ttttcacgct tgctagtcat attagggaag
     6601 aagcgtttca gaacctgtgg caattcctct gctagagccg tgtagtagtc aaaaccatac
     6661 tgggtatcgg tgtaccaacc attgctggta ttgggcataa caacgatgag attagttcct
     6721 cgaagcaagc gttctacatt ggtccgctta agccaactat tatgatttcc agacatcccg
     6781 tgcaaaaggt acaagacggg aatatcttca cactctggtt cttccactcg attggcatca
     6841 gggtagagga cattcacccc ccactccata tccaatactt gtgagtaata ctcgattttc
     6901 attactgcca tgattttctc cttctatttt tctataagaa aaagccgaaa ctcgactttc
     6961 tctctgttta tttcaacgat tattttgctt ccatgactac tggtaaaata gctggacgac
     7021 gcttggtttg gtcaaagaga tacttggtca aattatctcg aaccttccct ttaagatctg
     7081 cccagtcaaa gtcatctcct tgaagatact cttctaccgt ttggttaatc aattctgaac
     7141 tttcatggag aatatcgcga ctcttcttga gataaacaaa tccgcgcgta tgaacacgag
     7201 ccctagccac aattttcttc tcacgacggt tgactgtaat agccacgatg aaaattccat
     7261 cctctgacaa gaccttacgg tcacgaagaa caacatttcc aacatcacca atggcattcc
     7321 catcaatcaa gatatctcct gctgaaaccg atccagctgg aacaaagtct ccattctcgt
     7381 aagccatggt cgtccccttt ttaggaatga agatgtgttc tggcaacatc ccaactgcca
     7441 tggcagcctt agcgtgagca tccaactcac gatactcccc ttggacaggg aagaggtact
     7501 taggttgcaa aagattgatc atcagctgca aatcacgcac atttccgtgc cctgatacat
     7561 gtaaactttg ggtaatcaat ttgacaaccc cacctgcctg ataaatcata ttttccacac
     7621 gcgcaacaaa ggcttcttta gcaatagacg gagccgtagc aatatagacc aggtccccat
     7681 ccttgatttc tacataacga tggcgaccaa tcgacatctt acgaagtcca ttgataggtt
     7741 cacccatacg acctgtctca agaataatca actcatggtc ttcaaagcga gacatatctt
     7801 taggcttaat caagagaatt tcgttggcta aagacaactt cttaagacga atcgctgtgc
     7861 ggacgatatt ttcaatatca aatcctgtca agacgatacg tcgacctgtt ttatccgcag
     7921 cgtcaaaaat ctgctgaata cgagaaagat tactggaaac agctgcaacg atgatacgac
     7981 cttcccagtc agcaatagtt tgggtaattt catccctaac ttcactttca ctagccacct
     8041 gaatattgct gtctgcattg gccgaatcac tgaggagagc caggacgccg tcacgaccaa
     8101 tctctgccaa acgagcaaaa tcagttgcat aagattcact agccgtttgg tcaaatttga
     8161 aatcacctgt ataaacgatg cttccttccg atgtcttcaa gacaattccc agactctctg
     8221 gaacggagta agtcgtaggg aagaaggaaa ccactgtccc accaaaatca atctccgtat
     8281 tctcatcaat gacatggaaa tcattaaatt tcttaacggc atcatttcct ttgacaaaga
     8341 gctttgccaa ctcaatggtc aactcagacc caaatacagg aactttagcc tctgccaaga
     8401 gataaggtag agcaccaatg gcatccgcat gcccgtgggt caagaaaacc ccagcaatac
     8461 ggtcgctatt ttcaaaaagg taatccatgt ttggaatcac cacatcgacc cctaattgtt
     8521 cattttcagg atattttaac cctacattca aaacaaaaat ggactctcca atttcagcaa
     8581 tgtacatatt ttttccattc tcacgcacac caccaagtgt tgttaaactg atattactca
     8641 tttttcctcc aaaatcttag tttatcttga ttatagggca actctaccct cttattctaa
     8701 aagttctaat actttcagcc gaatcttttc ctaccattat accatttttt tgatgatttt
     8761 caaaatgaag gtctgttttc aaaaaagagt tgatttccca actctttcct aacttctact
     8821 ctttttccat caaaaaatca taaatttctt gcaccgtacc cagcgccatc atttcttggt
     8881 ctttaacggt ttgtttgaga ttttggtaaa tttgactttc tcctatctcc cgctttggcg
     8941 cctctttatt gactgtcatc acaccatctt ttatcgtcac aaagcctagt tcttcaaata
     9001 cttgaatcat cttgaccagc aagatttgtt gaatattaag atatgcagcc aaatctttca
     9061 gcttgtagcg aatatcaaac tctgggaact ggtaaatagt cttgtacaat ttggcaaact
     9121 gatctctagt cccataacct gtcagataat aggccttgtc aatatcattt ttgaaataga
     9181 cagcagagaa atgctgttcc tgaaaaatgg tcttcagctg agtaatatcc tctggaatgt
     9241 tttttacgac aatagcttca ctagccgcaa gatttggcag ttctccagga aaatccaaga
     9301 ctggaacacc ttctggcaag actgcatttt ttccacgaat gttaaaaagt tgaacacctt
     9361 ccactcgcgc atccaccatc atcaactgga gggcagtttg gccattccat tggttgacag
     9421 acaatttaac cgctaactct agattcttgg tttgagaaaa ctctgtcgcc catctgcctt
     9481 gaccaaaggc taccacttca aaactcgcct cacccttgga aattttcagc tttagatggg
     9541 cattacctgc ccccatagta cgagcacttt cgacctgaaa attcttgata taaaaaatag
     9601 gtttctgatt atccattcca aaaggagcta aacgttcaaa acttttgacc gtttccaagc
     9661 taagtgcctc caaatccaac tcttcatcta ggtttaactt attcttgcca ccagcatctg
     9721 cacctttttc acgaacataa tcttccaaaa cctgagataa atctgagagt tgctcaactt
     9781 ccagcgtcat acccgctgca cctgcatgac ctccaaaggc gatgaagagg tctcgatggg
     9841 gatccagagc ttcaaaaata tcgaccgctt ccacactacg agcactgccc ttggcacgac
     9901 cgtcttctat attaagaaca atgactgtct gtcccaattc ttccaataaa cgaccagcca
     9961 cgattcctag aaccccagga ttccagcctt ccttggccaa gacctgaacc ttcttctcag
    10021 gatccaccat ggtcttggct tcttcataga tagactgaac gatttccttg cgctcttcgt
    10081 ttttctggtg aatcataagg gcaatctcat gcgcttcctc atcatcaaat ccagtcaaca
    10141 aatcaatggc aggattggga tcatccaagc gacccaaggc attcaaacga ggagcaatct
    10201 ggaaaccaac cgtttcttct gttacttcgt tggcagcaat cccagccatg tccagcattt
    10261 cttgcagacc aatgcgctgg gtatgaccca acatttccag accatattga actaagatac
    10321 gattttcatc cgtcagactc accatatctg caatagttcc aatagcgacc aaatcaagca
    10381 attccacttg cacttcttct aacagggcac aagccaactt gaaagcaact ccacaaccag
    10441 ccaaatattt aaaaggataa tccgcatctg gatgttcagg atggacaata gcataagcat
    10501 ctggcagggt ttcaggcatg gaatgatggt ctgtcacaat gacatctact cccatagact
    10561 gagccaatgc aatagcctca tgaccagcaa ccccattgtc caccgtcaca atcaaggaaa
    10621 ttccttcttg ctcgataaag tatttataaa cactagcatt agggccatag ccatcggtaa
    10681 aacgatttgg caggtaaact cggcactccg caccaagttg ttccaaactt tccttcacaa
    10741 tagaagccga agtcatgcca tccgcatcat agtctccata aacgagaata ttttcccctt
    10801 cttcaatagc ctgacgaatc cgctccactg ccttgtccat atcatggagc agataagcat
    10861 catgtaagtc ctccaaggaa ggttctaaaa acttcttcag actttcttgg tcctgaatcc
    10921 ctctctcaaa caataaccga gccacctcag gacccagtcc agccttcttg gctatctttg
    10981 taaaatccgc atcttctacc tgcagggcaa actgccattc ataagtaggt gttatcaaaa
    11041 agacatccac tctttctaag aattctattg cttcattata acatgattta gacgttttct
    11101 ctatccagat tgctttttta taacatttta tagtatattg aaactagaat agtacacctc
    11161 tacttataaa atattgttag aaatcgattt gactgtcccg atcgatttgt ccttttctta
    11221 tttcactata gtgaattttt tcagatacgg tttgacaaga acattctttt attgtagaat
    11281 tgtgttataa aatctaacat aaaggagatc tctcatggct ttagtagaat ttaaaaacgt
    11341 cgaaaaatat tacggagact accacgcact ccgcaacatc aatctccgtt ttgaaaaagg
    11401 acaagttgtt gtcctgcttg gaccttctgg ctctgggaag tccactctta tccgtacgat
    11461 caatggttta gaggctgttg acaaaggaag tctcctagtc aatgggcacc aagttgctgg
    11521 tgccagccag aaagatttgg tacctcttcg caaggaagtc ggcatggttt ttcaacattt
    11581 taacctttat ccacacaaaa cggtgttaga aaacgtgaca cttgcgccca ttaaagttct
    11641 aggaattgat aaaaaagaag ctgaaaaaac cgcccaaaaa tatctggaat ttgtaaatat
    11701 gtgggacaag aaagattcct atcccgccat actatctggt ggacaaaaac agcggatcgc
    11761 catcgctcgt ggtcttgcta tgcatccgga actcctcctc tttgatgaac caacatctgc
    11821 tcttgatcct gagactatcg gagatgttct agcagttatg cagaaactgg cgcatgatgg
    11881 gatgaacatg atcatcgtta cccacgaaat gggctttgct cgagaggttg cggaccgcat
    11941 tatctttatg gccgacggag aagttttatt agatacgaca gatgtcgata acttttttga
    12001 caatccaagc aaacctcgtg cccaacaatt cctcagcaaa attatcaacc acgaaagtga
    12061 caaagtcaaa taaggaggcg cctatgaaaa aaaaattctt tttatcagca ttattgatta
    12121 gccttttcgg ccttgctgct gccaaaccag tccaggctga tactagtatc gcagacattc
    12181 aaaaaagagg cgaactggtt gtcggtgtca aacaagacgt tcccaatttt ggttacaaag
    12241 atcccaagac cggtacttat tctggtatcg aaaccgactt ggccaagatg gtagctgatg
    12301 aactcaaggt caagattcgc tatgtgccgg ttacagcaca aacccgcggc ccccttctag
    12361 acaatgaaca ggtcgatatg gatatcgcga cctttaccat cacggacgaa cgcaaaaaac
    12421 tctacaactt taccagtccc tactacacag acgcttctgg atttttggtc aataaatctg
    12481 ccaaaatcaa aaagattgag gacctaaacg gcaaaaccat cggagtcgcc caaggttcta
    12541 tcacccaacg cctgattact gaactgggta aaaagaaagg tctgaagttt aaattcgtcg
    12601 aacttggttc ctacccagaa ttgattactt ccctgcacgc tcatcgtatc gatgcctttt
    12661 ccgttgacca ctctattcta tctggctaca ctagtaaacg gacagcacta ctagatgata
    12721 gtttcaagcc atctgactac agtattgtta ccaagaaatc aaatacagag ctcaacgact
    12781 atcttgataa cttggttact aaatggagca aggatggtag tttgcagaaa ctttatgacc
    12841 gttacaagct caaaccatct agtcataccg cagattaagg aggataccct atgacagatt
    12901 tatcatcttg gacagcctat tttcaggatt ttggacaatt tttcaatggt ttcctcttta
    12961 ctcttgccct agcgattgga tcctttatcc tcgccatggt cttaggaatc ttctttggtg
    13021 ccatgtcaac cagtaaacgt ccaattttac gcattttagc tcgcatcttc gtggaatttt
    13081 accaaaacac tcccctcttg gtgcagtttg ttattgtttt ttatggccta cctcttatca
    13141 gtgaccacat catcatgatt ccaatttatt ggacagccgt tctctgcgtg ggactctatc
    13201 acggcgctta tatcgctgag gttattcgtt cagggattca gtctattcct agtggtcaga
    13261 tggaggccgc cttgtcgcaa ggttttacct atatcagtgc catgcgcttg attatcttgc
    13321 ctcaggcctt ccgcatcatt ctccctccat tgaccaacca aattgttaac ctcatcaaga
    13381 acacatctac tgtagctatc atctctggag tagacttgat gtttgtgact aagtcttggt
    13441 cggctctcaa cggaaactat atcccagcct ttttaggtgc tgctcttctc tactttgccc
    13501 tatgcttccc tgttgcccag tttggtcgca agatggagca agccaataaa aaagcctatt
    13561 cactttagga ggttactatg gaatctattt tagaaatttt aaccccagat aacctagtct
    13621 ttatctttaa aggatttggc ttgaccctct atatttctct gattgccatc atcctctcta
    13681 ctatcatcgg taccgtgctt gccgtcatgc gaaatggaaa aaatcctatc ttacgcatta
    13741 tttccagtat ttatatcgag tttgtgcgca acgttcccaa ccttctctgg atttttacta
    13801 tctttttggt gttcaaaatg aaatccacac cagcaggtat tacagccttt actctcttta
    13861 catcagcagc cttggctgag attattcgag gcggtctcaa tgccgtagac aagggacaat
    13921 acgaagcagg aatgtcacaa ggcttcacct cagcccaaat cctctactac atcattctcc
    13981 cacaagccat ccgcaaaatg ctaccagcca tcatttctca gtttgttacc gtgattaagg
    14041 ataccagtct cctctactct gttatcgccc tacaagaact ctttggagcc agccaaattc
    14101 tcatgggccg ttatttcgaa ccagagcagg tcttcagtct ttacatcctg attgccctca
    14161 tctacttcag ctttaaccta gcgatttcta gcctgtctca tatgctagcc aaacgttggc
    14221 aacaagctgc agaataatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
    14281 cgtactcaag tacagcctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
    14341 aaacagccac tctccagttc aattggagag ttttttgatg agagtagata tttatagacc
    14401 tcaatttgac accatacatt ttctatgata aaatgtaaca aattcattta caacaaatcg
    14461 aaatctaaat gaaatggaat tttctatgaa atcagtcaaa ggactactct ttatcatagc
    14521 tagttttatc ttgactcttt tgacttggat gaacacttct ccccaattca tgattccagg
    14581 actagcttta acaagcctat ctctgacttt tatcctagcc actcgtctcc cactactaga
    14641 aagctggttt cacggtttgg agaaggtcta caccgtccac aaattcacag cctttctctc
    14701 catcatccta ctaatctttc ataactttag tatgggcggt ttgtggggct ctcgcttagc
    14761 tgctcagttt ggcaatcttg ccatctatat ctttgccagc atcatccttg tcgcctattt
    14821 aggcaaatac atccaatacg aagcttggcg atggattcac cgcctggttt acctagccta
    14881 tattttagga ctctttcaca tctacatgat aatgggcaat cgtctcctta catttaatct
    14941 tctaagtttt cttgttggta gctatgccct tttaggctta ctagctggtt tttatatcat
    15001 ttttctatat caaaagattt ccttccccta tctaggaaaa attacccatc tcaaacgctt
    15061 aaatcacgat actagagaaa ttcaaatcca tcttagcaga cctttcaact atcaatcagg
    15121 acaatttgcc tttctaaaga ttttccaaga aggctttgaa agtgctccgc atcccttttc
    15181 tatctcagga ggtcatggtc aaactcttta ctttactgtt aaaaattcag gcgaccatac
    15241 caataatatc tatgataatc ttcaagccgg cagcaaagta accctagaca gagcttacgg
    15301 acacatgatc atagaagaag gacgagaaaa tcaggtttgg attgctggag gtattgggat
    15361 cacccccttc atctcttaca tccgtgaaca tcctatttta gataaacagg ttcacttcta
    15421 ctataacttc cgtggagatg aaaatgcagt ctacctagat ttactccgta actatgctca
    15481 gaaaaatcct aattttgaac tccatctaat cgacagtacg aaagacggct atcttaattt
    15541 tgaacaaaaa aagtgcccga acatgcaacc gtctatatgt gtggtcctat ttctatgatg
    15601 aaggcacttg ccaaacagat taagaaacaa aatccaaaaa cagagcttat ttacgaagga
    15661 ttcaagttca aataagtaat catactctcc tgggatttcc caggagagtt ttttatagcc
    15721 aaatgaaata agacctgaac gatggaattt tggcattcaa atcaattgat aagaatattt
    15781 tatagtggag tgaaatagga tacgaacaaa ttgattagga aaatcaaatg aatttataga
    15841 aatcttttag cagttatgtt gtcctattct agtttcgaaa cgctatagaa gcagcattgt
    15901 gctagtctag attcagttta ctatactaaa acgagtagct tggaatcaaa aaacccaccc
    15961 tcacaggcag gttttatctg tattattcag ctagattatg ctttaccttc tgaaccgaat
    16021 acgtcgatac gttcttcaac cgatgcttgg atagctttta caccgtcagc caagaattta
    16081 cgtgggtcga agagtttttt cttgtcgtat tctgcttcgt ttgcttcgta gtcacgagca
    16141 aatttacgag ttgcgttagc gaatgcgatt tggcattctg tgttaacgtt aactttggca
    16201 acaccaagtt tgatagctgc ttggatttgc tcatcaggaa tacctgatcc accgtgcaat
    16261 acgattggga atcctggaag agcttctgtc aatttttgca agtggtcaag gtcaagacct
    16321 tcccagttta ctgggtaagg gccgtggatg ttaccgatac cagctgccaa gaagtcgata
    16381 ccagtttcaa ccattgcttt agcgtcttcg attggagcca attcaccttt accgatgatt
    16441 ccgtcttctt caccaccgat agtaccaact tcagcttcta ctgagatacc tttagcgtgt
    16501 gctttttcaa caacttcttt agccaattta aggttttctt caactggaag gtgtgaaccg
    16561 tcaaacatga ttgaagtata accaacttcg atacactcaa gtgcatcttc gtagtgaccg
    16621 tggtcaaggt ggatagctac tggtacagtg atacccattg attcaacaag gttagcgatc
    16681 aagttgcgag caactttgta accacccatg tatttagcag cacccattga agtttggatc
    16741 aaaactggag cttttttagc ttctgctgcg cgcaagatag cttgagtcca ctcaaggttg
    16801 tttgtgttaa atccaccaac tgcataaccg ttgtcacggg ctgcttggac aaatttttct
    16861 gctgaaacga ttgccatttt atcaggcctc ctgtatattt ttatgggtca tcccatttac
    16921 attgttcatt ttatcacttt ttgccaaaaa aatctagttt ttcccgcagt ttcgattgat
    16981 tttcttctaa ctccatctat gtaaaccctt tctctcccta gtcttggacg acttttggaa
    17041 aatctataaa gaaggttaaa cgattctcct ccatctcgaa acgataagct aatttttcat
    17101 gttctaatag actcttaacc acaaagagcc ccataccaga ccccttgacc ttgcgactgg
    17161 cattgtcaga aaaagactgg gctagttttt cttgttcctc tgagctacag ctattttcga
    17221 taaaaagttc tccttctctt tctccaattc gaactaagcc acctggaaca gagtgcttaa
    17281 tggcattgct gatgagatta gaaagaatca acttcataac tgatgggttt agataagcct
    17341 gctgatgggt caaactattg tctatctgga gctctctttc cttggctagc aaggcataat
    17401 ctttgaccag attttgcgtc atctggagga ggtcaattgt ttccctatca tctcgcaatt
    17461 cctgcacaga agagagggaa agtatctgca gaacatggtg attgagttca tccacaatcc
    17521 ccaaggcaac tcccagatac tggtctctat tcttataacg accgatattc tctctcatat
    17581 tttcgattag gattttcaaa ctagccagcg gtgttttcaa ttcatgagaa gctcctcgta
    17641 ggaattcgac cttcatcttc tccagctgga gaatggcttc attcttttca tgcaagtccg
    17701 caataacagt caagagatgc tggtagaggc tattgatttg ttccttgaga ttgcctatct
    17761 catccttaga atccacgcgc aatcgcactt gggaatccag gtccatcatc cgacgggtca
    17821 cccgcttgat ttccaaaatc ggtgcaacaa tagtccgagc gtagatgtag gccaccaaga
    17881 gggaaatcag aaaggaggcc agcaaggtat agggaagaaa ctggagactg atttgctccg
    17941 cttccttttg taaatccatg gaagctagaa actggagaat catagtacca ccgtcttgcg
    18001 ttttcacctc gcgctcctca ataaagagag aggttgtctg gcggtctgtg tccagaggaa
    18061 gactgtcctt gacttctaac ttgtcctcgg tcatctcacc tttgacggtc cccttgatat
    18121 cactagtctg ggaatacaag tctaacactt gctcgatact ctgcctatct ttcccttcta
    18181 gggactgggc aatggctgtt gccttttgac caatggtttc ctgacgatga ctcagataag
    18241 tcgaaggaaa aagaaaataa atagctaaat gaaggcagat aaccagaaca ctaaatatcg
    18301 agaaggtata gataaatatc tttgtaaata aacctgttcg tttcattttc gctccaattt
    18361 ataaccaaca ttgcgcacag tgaggataca atccaagtct agctttttcc gcaattcctt
    18421 gatataaaca tcaataacac ggtcaaaggg aacctcatct gtcgctttcc agacggcatc
    18481 gataatctga gaccgagtca aggcccggcc ttcatttttc actagatagt ccagaatttc
    18541 caactctttg gcattgatag gcacttcttg acctgcgagg cttgcactgt agctttcaaa
    18601 gtccaccttg gtatccttgt aagaaaagat tcgtcctgta tcgtagtagc gcttgaaaat
    18661 cgcgtccacc ctcactttta agagggagag ggagaaaggt ttttccagat agccatctgc
    18721 caaagaggca aaggcactca tcttgtattc ctcatcctga aaagctgtca acatcaagac
    18781 aggaacctga ctggttttac gaatctcagc taggacttct aagccgttaa gcttgggcat
    18841 ctggatatcc agtaaaacca gggccacctc atagctagaa aattgctcca gagcttcctg
    18901 accgtccgct gcctcaatag tttcatagcc acaatccgtc aaataatcac tgaccccctc
    18961 acggatcatc tcttcatctt ctacaattaa aattttcata ctttaactgc tctctatttt
    19021 ttatttttct tagaataaat acctactcta ttttctatta tagtctcttg ctggcctttt
    19081 gtctgtaagc aactgaccac tagataaaac gttgtgaaat tcctttctca taaattccat
    19141 aactttagta tattatattt aagcactaaa gtacaaagaa agcaactgaa agcaatgatt
    19201 ttcaccactg ctttcagatt tattttgaat tgttaaatag ctattcctat ccactattct
    19261 tgaatagaaa cacaagatgc aatctttatt ccagactcat ttttttcaaa tttattcacc
    19321 atccagcaag agctcttttg gttgttttct aaggagattg cttgaagcaa gcgccataac
    19381 gagaaccact agaaccaagg caaggacaaa aatgatgata aagtctgatg tctgaatgga
    19441 aatgtctagg ctcgacaagg tcttgctaaa gccatctact tctgcaccgc caccaaggtt
    19501 agaggcttga gccgccttac tagcctgttt ggcaacacct gaagtcacat tggcaaggac
    19561 agtgtttcca attgcacggg cagtgtaatt agctaggaag taagcagaaa ctagagcagg
    19621 gatagcaatc aagatagatt cggtgatgaa ttgacccaag atacttgcct gcttgagacc
    19681 aatagagagg aggattccca cttccttgcg acgggcattg atccaaagac tgagcaagag
    19741 ggcaaggaga aggactgaga agctcaagct accccagaag aggaggttgg ccatcttgta
    19801 cataccagag atagattgct caagagctgg gtagttagag gagctcttga cgagtgtgta
    19861 gctcttccag ttgataccac tgatgccatt caactctttc ataacatcat ccaagttctt
    19921 gtctgctgtt acaaagaagg ttgcgtcccc ataaatggct gtgtcttctg tgtatccata
    19981 aagttttgca gcagtgtgaa tgtctgtaat agctgtgttt tcgtaaagtt cttgtgagta
    20041 ggttactgct gacttattat gaccatcaaa gagtcccttg attgtcactt caactgtttc
    20101 cttggctcct ttttcattat ctgcatcgta gatattagag tccagtttaa ccttgtcccc
    20161 tactttccag ccgtgtttgg ctgccaagtc cttgtgcaag aggattttat ccttgtcgtc
    20221 gttggttaag tgctctcctt cgactagttt ataagaacca gagacaaact tatcttcttt
    20281 agaggagtca ttgacacctg taatcatcaa gctacttcca aaacgtttgg cacgatcagc
    20341 agtgagattc ttcttggttt ctggcgtttc aatcaggtca tatccagtca aatctccgat
    20401 agcgttgata cgtttgacat aagactcaat ggccttgttt tcggtgattt ttttgatgtc
    20461 ttcacccttg atattcccag caccacgagg cgttccttgg ttgacgcgac gattgatttg
    20521 catggagaag ctattggtga tatttttaaa ggtctcctga gaagccttgg cagtagctcc
    20581 cttgattgac aagccgacca aactcaagct cgccataagg agaataatca ggaagatgac
    20641 aatcgatttg aaaaacttcc ttgtaacata ggcaaatgcg ttgtgtaaca tagattccct
    20701 ttctagattt tgttttaatc attctatcaa aataagctca aattatttac tagtattgcg
    20761 cgtttcagtc agtttcttat cctttaattc aagtgtaata tctgacgctt gtgccacttc
    20821 tttactgtga gttacgacaa tcacacattt acctgttttc tgggcaagtg atttgagtag
    20881 ttcgacaata tctccagcag ttttaggatc cagatttcct gttggctcat cagctagaat
    20941 aactggagct tctgagacca aactgcgagc aatggcaaca cgttgctgtt gaccacctga
    21001 taactggaga acattccgct taatctggct ttcatccaaa ccaagctcaa gaagtgtatt
    21061 cttgcttgcc tttttgttga ccaattggat attttccagc ggagaaagat aatctatcaa
    21121 gttataattt tgaaagacca gggaaatatg gtgcatgcga tggtaagaat agcccttctt
    21181 acgaatatcc tctccttgaa aaaggataga accttcaaca ggactatcta gaccagcaag
    21241 tagggacaag agtgtggatt ttcctgctcc tgactcccca ataatactgt aaaattttcc
    21301 gggttcaaaa ttataattga tctgatatag gactgcttca gcagtattct tataacggta
    21361 ggtaacatct tgtaattgta ataaagtcat gatttctcct tcttaactaa tagatgataa
    21421 aatttctttc ggtgattttc taaataagaa taggaaacaa agggctacag ataagcaact
    21481 aagcagaact agaaaaacat aggattctgc aaaagataag atgctagttg ataaactgct
    21541 tgctttggct agtgtatctt gtaagcttac ctgatctcca cttgctagta gagtttggag
    21601 taggtaagtt gtgattccgt ttcctgcaac aaatgctgga agcaaagctc caagagatac
    21661 caaaactacc tctaaacaga attgtaggaa gatcgagctc ttgccttttc caagtgcaag
    21721 taaaatcccc acttcataga cccgttctct caaccagaga gacaaaacca gaattaaggc
    21781 tccagctcct gctatcaaca tcccataaag gaagatggtc aggaaggttt ggaaagttgc
    21841 aactgagtct ttgatttgtt caaaagcctt gttttccttt tcgacttggt agccttgatt
    21901 ttccaaggcc aagttttcta cctgcttcat gagtccgtcc atttccttag gattttctac
    21961 atagaagcgt gctgcactga cttgagcttc actattgccc aaaagggttt ggctactttc
    22021 ataatctgta aagacttgat tttcactgaa gtcagaagac aagcctgtga atttctcttg
    22081 ttttttacca gaaaagatgc cgataatctc aaactctact gtttgtcctt ttccagattc
    22141 agactgacca gcatccaagc caatcttgtc atgaagtgaa agaccgttct tcttagccaa
    22201 ttcttcgtgg ataaggattt tcttggaatc ccctttttga aggtgtcgcc cttcttttag
    22261 attgaaagcc gaactggtaa aggttacatc cttggatgaa tcctcaagag ccgttaagct
    22321 aaccaagtta ttgtctgcag ctgataaatc atcacgctcc acgctctgct cgccagtcac
    22381 tgcttccttg tcttttagtt ttgcgaccgt ctcaagttca ggagagacat tttccagccc
    22441 cttaatcttg cttacagatg ctaggtctga caacttgaat gtctgaccat tctctatctt
    22501 cttaatagaa aaagatgtat tgagtgattt ataaagattg ctttctactg ttttgttgga
    22561 cttcatcaga gtcaaacagg ctgaaattcc ggccaataag accaataaaa tcagaaataa
    22621 aataaaactt ctcagtcgct ttctgctgac ataagcccaa gatctttgga ttggattcat
    22681 ttgtcacctc catatttgta agactattat aaaacccaaa tatgaaatgt ttatgaaata
    22741 cgaaaaaaaa tatcgagtag gggataatct ctagcccctc tcacaccacc gtacgtg
//
LOCUS       DAVBNN010000029        22634 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBNN010000029 DAVBNN010000000
VERSION     DAVBNN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.029"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ847_001211"
     CDS             complement(339..1319)
                     /locus_tag="VQ847_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3050556.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ847_001212"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ847_001212"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3050557.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ847_001213"
     CDS             complement(3669..4772)
                     /locus_tag="VQ847_001213"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3050558.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ847_001214"
     CDS             complement(4762..5130)
                     /locus_tag="VQ847_001214"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3050559.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ847_001215"
     CDS             complement(5169..6200)
                     /locus_tag="VQ847_001215"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3050560.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ847_001216"
     CDS             complement(6202..7233)
                     /locus_tag="VQ847_001216"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3050561.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ847_001217"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ847_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3050562.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10262)
                     /locus_tag="VQ847_001218"
                     /pseudo
     CDS             complement(9973..10262)
                     /locus_tag="VQ847_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10290..10922)
                     /locus_tag="VQ847_001219"
     CDS             complement(10290..10922)
                     /locus_tag="VQ847_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3050563.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10926..11567)
                     /locus_tag="VQ847_001220"
     CDS             complement(10926..11567)
                     /locus_tag="VQ847_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050564.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11560..12351)
                     /locus_tag="VQ847_001221"
     CDS             complement(11560..12351)
                     /locus_tag="VQ847_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050565.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12536..12871)
                     /locus_tag="VQ847_001222"
     CDS             complement(12536..12871)
                     /locus_tag="VQ847_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050566.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13011..13346)
                     /locus_tag="VQ847_001223"
     CDS             complement(13011..13346)
                     /locus_tag="VQ847_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050567.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ847_001224"
     CDS             complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ847_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3050568.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14761..15474)
                     /locus_tag="VQ847_001225"
     CDS             complement(14761..15474)
                     /locus_tag="VQ847_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET3050569.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ847_001226"
     CDS             complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ847_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3050570.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16368..17537)
                     /locus_tag="VQ847_001227"
     CDS             complement(16368..17537)
                     /locus_tag="VQ847_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3050571.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ847_001228"
     CDS             complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ847_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3050572.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18151..18516
                     /locus_tag="VQ847_001229"
     CDS             18151..18516
                     /locus_tag="VQ847_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3050573.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18521..19216
                     /locus_tag="VQ847_001230"
     CDS             18521..19216
                     /locus_tag="VQ847_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050574.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19233..20000
                     /locus_tag="VQ847_001231"
     CDS             19233..20000
                     /locus_tag="VQ847_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050575.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20353..21552)
                     /locus_tag="VQ847_001232"
     CDS             complement(20353..21552)
                     /locus_tag="VQ847_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050576.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21549..22442)
                     /locus_tag="VQ847_001233"
     CDS             complement(21549..22442)
                     /locus_tag="VQ847_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050577.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
BASE COUNT         6646 a         5106 c         4192 g         6690 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatcctttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctga ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc cccccagaat cggactgccc caaggaagaa agaagaaagc aatccagatc
    10201 aacagaacta aaccaatata gaccttagaa tagcgtgtaa taaatgattt tagatgtgcc
    10261 ataagccatc tcctaggatt gtatatcctt tacatttgta tatgtccatt ttcgacaact
    10321 aatacatctg tacaaaggtc tgaaatatct tccgatatgt gcgacgtcag gataaccaga
    10381 ccattttctt ttttcaggta agataaaatg acctgtttgg ttaacctcac acttttctca
    10441 tccaaagcat tcataggttc atcgagaaag agtatagaag gagaggaaat aaaggcttga
    10501 atcaaggcca ttttttgctt tgttcccaag gataaatgcc ggtattcaac gtcttcaaat
    10561 tcctgtaaat catagtattg aatccaatag gcaattcttt tttccgtaac tttagatgaa
    10621 aaatacctta acagttccaa attttctctc agggataaat gagataaaaa ctcgactttt
    10681 tcaattaaaa ttcctgcatc ctgaatataa tgatttttta tcccgtaaac tttaccatct
    10741 tgaagaactt ttcctttgtc aagcttaata taaccagcaa gtatctttaa aagaaccgtc
    10801 ttgccagatc cattatcacc tttaagtcca taaatttttc ctgattgaaa caccaaattc
    10861 aactgattta aaataggtct tttcccataa attttctgtc catttataat ttcaagtctc
    10921 atcgtttatc ctttcttaaa tttctcttcc aagcgactaa gaatcaacat aactaataag
    10981 cttaagagta ctaaatacac tgttacaata tgatccatca tccattcttg tcccacaaat
    11041 gccaaaaaat agagaaaaaa agaaaaacca gcgcccgcac taatcagtgc tatcagataa
    11101 gacagtagta agtacaacat cattaactga gcaagtaaaa agaaaagtgc gactgttttg
    11161 aaatgaattc ctagcggaag taaaccaaga aaccagacaa acaaatcttg agtaaaaaat
    11221 ttagaaatga caaccaatcg tttccttgta taatcgaaaa aggagcttga ttgatagcga
    11281 atcaagtgat ggtaatggtc tgccaaatca ctttcaagta aaatgacaga gagccatcct
    11341 accatgaaaa gcgaaaggtt taacaagagt ttggggattt ctaaattcgc ttcagaatag
    11401 tcattatagg aaaaaattga aatcaattct ctcttgaaaa agataacagc atcctgcttt
    11461 tgaaccgctg ttgacaatag atagtttatc aaaatcatca tcagaactat acgaagtagt
    11521 aaaacgatct ttctctttag ccaaatattg ttaaaattct taaacattat cttcatattt
    11581 tttaagtacc atataaggga caacataaag gatataagga gtaaagagtt tcatcaaact
    11641 tacatcccca tagctagctt gcatcaaact cgtcatagga accatatagt aaggcaaggc
    11701 actatagagc agcatagaac caagccaaag aaacatcaaa taggtgattg ccgaacgagt
    11761 cacattcccc acataatcaa ctatttgtaa aaaatagatt gcattgatga aaataccgat
    11821 tagtaggaca caagtaaaga acaaatagct ttttatctct ccatctagga gtctttgtaa
    11881 accactccca tcagaaaata gagaattcca ttcaagagga gaaaaagtcc caaagaaata
    11941 ggttataatt gcaattatca gcacagtcac taaatatatc aaacaaggga tacttgcaac
    12001 ttgcaaagtc aactttcttt ttaacccttg atagctcact tctcttccaa tactcaatcg
    12061 taaaacttta tttttcagct caatatattg aaaacctagc aaaacaatga tgattggaat
    12121 aataaatgat tgataaaaac ctagattgaa ctggagaata cgaaaatcta atgctgattt
    12181 taataagtca tttttaattg cttgtccatc gaatttagct agatcgggcg catgaatatc
    12241 aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag
    12301 caagacataa acaaatttat gccttgccaa agttaagaga ggaatcttca taagccacct
    12361 cctacaaata gaaagtaata taatactcaa tgaaaatcaa agagcaaact aggaaactag
    12421 ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagttaca
    12481 tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat
    12541 gccttccgcc tttagacttc cctagttccc gtctcaagtc aagcattttt ttgaaacaga
    12601 tatagtctaa ccagtcacta gcaaaagcga taagtagtaa taatagccaa ataccccata
    12661 acttgatatc tgtcaaattt ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc
    12721 aagcaaggct aaaaagagca tagagggtga tgtaaatcca gtaaaaatag taaaaaattg
    12781 ggaaaatctt actatctctg tttgcctttt caatccagct gaaaaagtaa aaacagggca
    12841 ataagattat cattttaaac aagtattcca tcacaaacct cctcttttaa attgttttct
    12901 ttagtttcgt tctattaaat gttattacca atataaacct tggaatagcg tgtaataaat
    12961 gattttagag gtaccataag ccacctccta caaatagaaa ccgatataaa tcaatgcctt
    13021 ccacccttag acttccctag ttcctgtctc aagcgaaaca tttctttgaa acaggaataa
    13081 gttaaccaat tcataccaat agctagcaga ataaaaagaa accaaatgcc ccataacttg
    13141 atatctgtca catttctcaa gacggtattg aaaaacagaa ctgaaacaac tgtccaagca
    13201 aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa aataataaaa aattggaaaa
    13261 aacttactat ttctgttggc cttctcaatc cagttatcaa aataaaagta cggtgctaaa
    13321 agtaagaatt taaacaaatg ttccatcacc gacatcaccc tccttctttt gatagcgttt
    13381 tctattattt tattatatca aaaaaatccg gaactgtcat tccagattct acttttttat
    13441 ttgcgttttc ttgcgatgag atgaatcggt gttccctcaa aaacaaaggc cttgcggatt
    13501 tgattttcca agaaacgcag gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg
    13561 acaaaggttg gtggtttggt tgccacttgg gtcgcataga aaatcttgag acgttttcct
    13621 ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga tgacatcgtt caagacagct
    13681 gatggaatac gtgtattttg actttcgctg atttgcttaa tcatctcagg aagtttgtgg
    13741 agacgttgct tagtcaaagc tgatacaaaa ataatcggtg cataaggcag gtattggaac
    13801 tgctcacgga tatcttcttc ccagtttttc atggtatggt tgtctttttc aagcgtatcc
    13861 cacttgttga ctacgataat cattccttta ccagcttcat gggcaaatcc tgcgatacgc
    13921 ttgtcgtact cacgaatgcc ttcttccgca ttgatgacca tcaagaccac atctgaacgg
    13981 tcaatagcac gcatggcacg cataacagag tatttctcag tattttcata aaccttacca
    14041 gacttacgca taccagccgt atcaatcatg gtaaactctt gaccatctgt atctgtaaag
    14101 tgggtatcaa tagcgtcacg agttgttcca gcaacaggac tggcaatgac acggtcttct
    14161 cccaagatag cattaatcaa gcttgatttt ccaacgttag gacgaccaat caagctaaac
    14221 ttaatgacat ctggattttc ttcttcatat tcatttggaa ggttttccac aatcgcatct
    14281 agtacatccc ctgtaccgat accatggaca gatgagatag gcagtggttc acccaaaccg
    14341 agagcataga aatcatagat atcatttctc atctcagggt tatccacctt gttgactgcg
    14401 aggataactg gtttgtgggt cttataaagc ttgcgggcta cgtattcgtc tgcatcggta
    14461 attccttcct taccggacac gacaaagacg ataacatctg cttcttccat ggcaatttct
    14521 gcctggtgct tgatttgttc catgaaagga gcatcgacat catcaattcc tcctgtatca
    14581 atcatgctaa aagaacgatt gagccactca cccgttgcat aaatacggtc acgtgtcact
    14641 ccttcgacat cttctacaat ggagattcgc tcaccagcga tccgattaaa tagggttgat
    14701 ttcccaacat tgggacgtcc tacaatggca atagttggta gggccataat ttctcacttt
    14761 ctacaataat ttcttctgtt caagattttt tctagttgag cttggttcag cttgaccaaa
    14821 ctgttctgct aggcgctgac tccagcttgt ggtcgcacgc cccccagcat agtcagcctg
    14881 cacacggtca taagcttgga ttgtctcagt tgactgttct tggtattctt cctcaaagac
    14941 aacattctct agtggcagtc tcggtttcac atcatgatgt tgatttggca cacccagtgc
    15001 catcccaaag acagaatagg tgtagtcagg taggttaaag agctctgcca cttcttcaga
    15061 cttgtatcga accaaaccga taatcacacc accatagccc aagctttcag ctgccaacaa
    15121 ggcgttttgt ccagcaagag ctgcatcgac cgaactaatc aagagacctt ccacaccttg
    15181 gggttggaag gtgtcggtat gaagtcgggc tcccttttct gctcggttca aatctccgac
    15241 aaagagaagg aaaacagcag actggcgaat ggcttcttga ggtaccaatt catacaaggc
    15301 atctttcttc tcttgacttc gtaccacaat cacagagtag gattggaaat tcttccaaga
    15361 tgatgccatc tgggctgctg tcaaaatctc atttaagtct acttggggaa tttcttgctc
    15421 tttaaacctg cgcactgaag tatgagcctt catcaattta atggtttctg tcatcgacgg
    15481 tttactcctt ctaaacgagt ctcctcagcc aaataacgga tgcgttccat gacccgtctg
    15541 gcttcccagg tttcgtcatt tccatgtttc actttcgcaa aatgcttctc caaatcttca
    15601 aagttgaagt tggatgtgaa aaaggtcggt aaattttcct gcatccgata ttggagaatg
    15661 acctgcagga tttcgtcacg tacccaaacg gttgattgct cggcgccaat atcatctaaa
    15721 atcaggacct cagacagctt aatctcatcc accaaggtct taacattgcc atcactgata
    15781 gcatttttga catcaatgac aaagctagga tagtggagga gagttgatga aacaccacgt
    15841 ttttctgata aatcatgagc taaggccgcc accatgaaac ttttacccac accaaagtct
    15901 ccatataagt aaagaccttt tcgaatagct ggatattgct ccacgaaggc tagtagcttt
    15961 tcaaaaactg gtaagcgccc caaatcatcc aagtcaactt gagccaaact agctttcttg
    16021 agactggctg gtagattgat taacttgaga cggttcttaa tagccgcttc tttttcagcc
    16081 gcgattagct caggagtttc ttcatatgaa acatctgcat agccatgatt cttaaccaaa
    16141 atcggcttgt agcctttggc aatataatcc gtatccccac ggagaaactt gtcacgctcg
    16201 gtgatgtact gattaaactt ggagatactg cgatttaatt cctctggagt caaggattct
    16261 tgctggataa aagccgcaac atcagggtcc ttcatgattt tctggaccaa atcttgataa
    16321 taaaaacggc tgggttgacg tttgagtacg tctccgacac tttccatcta atctcctcct
    16381 ttttctaatc gagctaatag ttcttgcttc ttacgttcta gttccagacg agtttcctcg
    16441 ctggtttcat tcttatattc aggattactc catttaggaa cattggtttt tactggggca
    16501 gtctgattct gtttttgtgt ttttgctttc tgtcctcgct cacggatgcg caagactgcc
    16561 ttttctgccg aatgaatctt ttgataggca tagtcattgg ctaccttcat ggcatatttc
    16621 tcattgatat ttgccgaatc gaccttatta aaggtcaata aaagaatgat attgatgact
    16681 tcgtccagca agcccaagcc agccatctgt tgcaagagtt ctctttctgt ttgggtaatg
    16741 gttcccttgc gtgtttgctt gatttctgcc aagaactgca gggcagtttt acttttggct
    16801 tctttgataa tggttgtttc cttaagacta aagtcagagg aaactggttt ttgagcaatt
    16861 ttttcacgca tgcgtttggt tgaaataacc tgagaaacag ctgttgactt ggccaattga
    16921 taggtttcaa accaagtcca tttcttctcc tcggcaatag caaagaggtt taagacatcg
    16981 gactgctcat ccgcaaaacg aagtccatct cgagccatca gctggcgaaa atgttccaag
    17041 tcaaaatcat tggccacttt cttcttgaga ccaaggtctt cttgactgcc tagttctgcc
    17101 aattctggaa agacttgatt gagtgagaca ggtatttctt caccatcagc actttcaact
    17161 ttcaaatcct ccacagcaga gtcgccaatc tttttctcta agagtctgcg ataaacagga
    17221 tgctccaaga agtcttgact agatagagga gcatggaggg ctagctgata aacatccccc
    17281 ttttgataga gggtcaagag attaaaagca gataagattt tcaatgattt tatcagtcta
    17341 tccatcccaa agttgagatg attgaggata cttgaaaaaa gatattcctt tctaccatta
    17401 tcccaaaaac tgattgtata aagataaagg ctcagtgcct cctgaccgat aatcgggagg
    17461 tagcactgta ccagagatga ggtatcttgc gacacccgat tattctttag ataagaaaaa
    17521 cggtcaattg gcttcattta tctttccttt ttctttttag aggactgggt gatttgttgg
    17581 agcaagctct ctaactcact gacatcctta aaactacgat agacactagc aaaacgtaca
    17641 taggtaatct cgtccaattc agccaactcc tccatgacga gtgaaccaat gtcctcactt
    17701 tgaatttcat tttcatttcg accacggagt ttctgttcga tacgattgac taccatgttg
    17761 atttcatcac ttgacacagg acgtttctgg gctgagcgga taatcccatt aaagatttta
    17821 tctctggaga attgttcccg tgtaccatct tttttaacaa ccactaaggt tctttcttct
    17881 actcgttcgt aggttgtaaa acggtgttgg cattcgtcgc actcacgtct tctacgaatg
    17941 gtgttccctt cttctgcttg gcgactatcg ataacacttg acttggtagc cccacatttt
    18001 ggacaacgca tcctttccct ccttatcgtt ttcttttcat tataccattt tttaagcgat
    18061 tcccaaaaca attcttcttt ttgcttgaca agttttttgt tttgttgtat tatttaatta
    18121 agacaaaagg ataagagaaa ggagactaag atgtcctgga catttgacaa caaaaaaccc
    18181 atctatttac agattatgga gaaaatcaag cttcagattg tttcccatac actggaaccc
    18241 aatcaacaac ttccaaccgt gagggagcta gctagcgagg ctggtgtcaa tcccaatacc
    18301 atccaaagag ccttatcaga ccttgaacga gaaggatttg tctacagcaa gcgaacaact
    18361 ggacgatttg tgactaagga taaggagcta atcgcccagt cacgcaaaca attatcagaa
    18421 gaagaattgg aacacttcgt ttcctccatg acccattttg gctatgaaaa agaagaacta
    18481 ccaggcgtag tcagtgatta tattaaagga gtttaagcct atgtcattac tagtatttga
    18541 aaatgtatcc aaatcatatg gagcaacacc agcccttgaa aatgtttctc ttgacattcc
    18601 agctggaaaa attgtcggcc ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa
    18661 actaattaat ggcctcttac aaccagatca aggacgtgtc ctcatcaacg acatggaccc
    18721 aagcccagca accaaggccg ttgtagctta tttgcctgat acgacctatc tcaatgagca
    18781 aatgaaggtc aaagaagccc taacctactt caagaccttc tataaagatt tcaatcttga
    18841 acgcgcccat catctacttg cagacctggg cattgatgaa aatagtcgtc tcaagaaact
    18901 atcaaaagga aacaaagaaa aggttcaact gattttggtt atgagccgtg atgctcgtct
    18961 ctatgttttg gacgaaccca ttggtggggt ggatccagca gcccgtgctt atatcctcaa
    19021 taccattatc aacaactact caccaacttc taccgttttg atttctaccc acttgatttc
    19081 tgatatcgag ccaatcttgg atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca
    19141 aggaaatgta gatgatattc gctacgagtc aggtgaatcc attgaccaac tcttccgtca
    19201 ggaatttaag gcctaagcaa aggagattat ttatgttttg gaatttagtt cgctacgaat
    19261 ttaaaaatgt taacaagtgg tatttagccc tctacgcagc cgtgctagtc ctttctgccc
    19321 tcatcggaat acagacacaa ggctttaaaa atctacctta ccaagaaagt caggctacta
    19381 tgctactttt tctagctaca gtctttggtg gcttgatgct tacacttggg atttcaacca
    19441 ttttcttgat tattaaacgc ttcaaaggta gtgtctacga ccgacaaggc tatctgactt
    19501 tgaccttgcc agtttctgaa caccatatca tcacagccaa actaatcggt gcctttatct
    19561 ggtcattgat tagcaccgct gtattggctc taagtgctgt tattattctg gctttaacag
    19621 ctccagaatg gattcctctt tcttatgtga ttacatttgt agaaacacat ctccctcaga
    19681 tctttcttac aggtatatcc ttcctactaa atactatttc aggaatcctc tgcatctacc
    19741 tggctatttc cattggacag cttttcaatg aataccgtac agcactcgct gttgcagtct
    19801 acattggtat ccaaatcgtc attggattta ttgaactttt cttcaatctt agttctaatt
    19861 tctatgtcaa ttcactggta ggactcaatg accatttcta tatgggagca ggtatagcca
    19921 ttgttgaaga actcatattc atagctatct tttatctcgg aacctactac atcttgagaa
    19981 ataaggttaa tttgctttaa ataattttta cctagatatg taacatactc atagaacaaa
    20041 agagaccagg caaaaagtct ttacaattag aaaacgcata gtatcaagtg ttaaaaatcc
    20101 ttgatattat gcgttttttg tgagctgact tatttccttt cactatatcg caaaatgaaa
    20161 taagaacgga acgatgggat tttggaattc aaatcaattt ataagaatgt tttagaagta
    20221 atattatcct attccagatt cagttcacta tacaattgag ttttcaagca acctgtttac
    20281 ataatgtgta cataattagg ttcgtgattc cacccttttc acctttaaaa acctcgcttt
    20341 cgcaaggctc ttctatttat aagataaggc acgtttaaag gttttccaaa tccctaaatc
    20401 atccgtttga agaacgagac tagcatacat gcgtccgata aatcctgttg ctaccaccgc
    20461 aaaaatcact gtaatagcaa gtgaaatcca tgcttccgct ccctccgcat agccattaat
    20521 cgttcgaaac ggcataaaga aggtcgaaat aaagggaata taagaaccaa tcttcaagag
    20581 gagattgtca ccagctgcac ctagagctgt cactccaaaa aaaccaccca taatcaaaat
    20641 catcaaaggc gacaaggctt tccctgagtc ttcaggacga gaaaccatag atcctaggaa
    20701 ggctgccaag actacgtaca tgaaaagact gatcaaaata aagagcaagg tattcagtga
    20761 gatagcatct cccaagtgat ccaaaatacc agactgagcc aagaatggca aatctttaaa
    20821 gagcaaaacg gcagccagac cacctacaac atagatccca atatgcgtta aaatcactag
    20881 aaacagagcc atcatccgcg catagaaata gtgacttgcc cttatgctag aaaagacgac
    20941 ttccataatt ttggtgcctt tttcactggc aacttcctga gctgttacac ccgcataggt
    21001 aatcagaatc atataaagaa agaatcctaa ggcacctgct gcaattgttt gaataaactt
    21061 tttattttcc ttggcttcat caatcttttc tgtgaattga attgtctgcg ctaagcgttt
    21121 ttcctgctct tgagacaagg aagcagttga acgattaagc tgattttgca gttcattgag
    21181 tgtacctgta acctcaaatt taattccatt ttcaagcgat gtttcgccat gataaactgc
    21241 ctttagaaca ctatcttctt gatcaatggt caaataacct tttaattttt cttctttaat
    21301 tgcttctttg gcacttgctt cgtctttata gtcgaagtta acaccattta cattcttcag
    21361 tccttctgct acagatggca ctgttgtcac tactgccact ttattatttt tagccataga
    21421 agaaccttgg agatgcccaa ttcctacaga gattcctaaa aagaggaacg gcgaaatcac
    21481 cataaagaag aaactccatg actcgacatg tcgaagatag gtttccttga ttacaaccca
    21541 catatttctc atacttccac tcctgattct agtttaaaga tttcatcgat agttggcgct
    21601 tgttggtcaa atgttgcgat atattgacct tgagtcaaga ttgggaagag ttcccttcca
    21661 gcgctctcat cctccaaaat caatttccaa ctgccttgtt tggtcaagct cacctgtttg
    21721 acatgaggaa gattttccaa ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt
    21781 ttcccgtatt gattgcggac atcctgaact ggtccgtgca agaccacacg gccatctcga
    21841 atcatcagaa tatcgtcaca aagttcctca acattggtca tgacatggtc agaaaagata
    21901 atggttgctc cgcgctcttt ttcctgaaaa atgacttgtt tgagcaattc tgtattaact
    21961 gggtccaatc cactaaaagg ctcatccaag ataatcaggt ctggttcatg aatcagagta
    22021 ataatgagct gaatcttctg ctgatttcct tttgacagac tcttgatttt atctgtcagc
    22081 tttcctttta cttccaacct cttcatccat tgagggagtt tttctttgac ttctttggca
    22141 tccatgcctt ttagagtcgc caagtagcga acttgttcaa gaactgtcaa tttaggcatg
    22201 agactgcgtt cttcaggcag ataaccaatc cgagcataga tctcctgacg aatatcctga
    22261 ccatccagac cgatttctcc ctgatattct aggaatttta aaatactatg gaaaatcgtt
    22321 gtttttccag caccattttt tccgactagt cccaaaatac gacctggtcg cgcttgaaag
    22381 tcaataccaa acaaaacttg cttggatcca aaacttttct ctagacttct tacttctagc
    22441 atctttcacc tccgaaattt cttgcactca ttatactcct ttttgatagc ctttacaatg
    22501 ttttttgtcc atttttagaa gactattgct gtgtaaaata tggcctggag cacttttata
    22561 ctcaatgaaa atcaaagagc aaactaggaa gccagccgta gactgctcaa agtacagctt
    22621 tgaggttgca gata
//
LOCUS       DAVBNN010000030        22335 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBNN010000030 DAVBNN010000000
VERSION     DAVBNN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.030"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(307..594)
                     /locus_tag="VQ847_001234"
     CDS             complement(307..594)
                     /locus_tag="VQ847_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050578.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(604..1014)
                     /locus_tag="VQ847_001235"
     CDS             complement(604..1014)
                     /locus_tag="VQ847_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3050579.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1082..1813
                     /locus_tag="VQ847_001236"
     CDS             1082..1813
                     /locus_tag="VQ847_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050580.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1810..2859
                     /locus_tag="VQ847_001237"
     CDS             1810..2859
                     /locus_tag="VQ847_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050581.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(3027..3356)
                     /locus_tag="VQ847_001238"
     CDS             complement(3027..3356)
                     /locus_tag="VQ847_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3050582.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3633..3971
                     /locus_tag="VQ847_001239"
     CDS             3633..3971
                     /locus_tag="VQ847_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3050583.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3976..4713
                     /locus_tag="VQ847_001240"
     CDS             3976..4713
                     /locus_tag="VQ847_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3050584.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4727..6067
                     /locus_tag="VQ847_001241"
     CDS             4727..6067
                     /locus_tag="VQ847_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3050585.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6111..6266)
                     /gene="blpC"
                     /locus_tag="VQ847_001242"
     CDS             complement(6111..6266)
                     /gene="blpC"
                     /locus_tag="VQ847_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3050586.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6323..7684)
                     /locus_tag="VQ847_001243"
     CDS             complement(6323..7684)
                     /locus_tag="VQ847_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3050587.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPFSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7695..9848)
                     /gene="blpA"
                     /locus_tag="VQ847_001244"
     CDS             complement(7695..9848)
                     /gene="blpA"
                     /locus_tag="VQ847_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3050588.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10130..10384
                     /gene="blpM"
                     /locus_tag="VQ847_001245"
     CDS             10130..10384
                     /gene="blpM"
                     /locus_tag="VQ847_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3050589.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10400..10603
                     /gene="blpN"
                     /locus_tag="VQ847_001246"
     CDS             10400..10603
                     /gene="blpN"
                     /locus_tag="VQ847_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3050590.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10847..10996
                     /gene="blpO"
                     /locus_tag="VQ847_001247"
     CDS             10847..10996
                     /gene="blpO"
                     /locus_tag="VQ847_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3050591.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11100..11219
                     /locus_tag="VQ847_001248"
     CDS             11100..11219
                     /locus_tag="VQ847_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3050592.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11687..12058
                     /locus_tag="VQ847_001249"
     CDS             11687..12058
                     /locus_tag="VQ847_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050593.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12687..13070
                     /locus_tag="VQ847_001250"
     CDS             12687..13070
                     /locus_tag="VQ847_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3050594.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13122..13811
                     /locus_tag="VQ847_001251"
     CDS             13122..13811
                     /locus_tag="VQ847_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3050595.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13853..14086
                     /locus_tag="VQ847_001252"
     CDS             13853..14086
                     /locus_tag="VQ847_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050596.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14237..14848
                     /locus_tag="VQ847_001253"
     CDS             14237..14848
                     /locus_tag="VQ847_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3050597.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            15009..15803
                     /locus_tag="VQ847_001254"
     CDS             15009..15803
                     /locus_tag="VQ847_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3050598.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15800..16435
                     /gene="trmB"
                     /locus_tag="VQ847_001255"
     CDS             15800..16435
                     /gene="trmB"
                     /locus_tag="VQ847_001255"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3050599.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16561..17040
                     /gene="rimP"
                     /locus_tag="VQ847_001256"
     CDS             16561..17040
                     /gene="rimP"
                     /locus_tag="VQ847_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3050600.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17084..18220
                     /gene="nusA"
                     /locus_tag="VQ847_001257"
     CDS             17084..18220
                     /gene="nusA"
                     /locus_tag="VQ847_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3050601.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18242..18535
                     /locus_tag="VQ847_001258"
     CDS             18242..18535
                     /locus_tag="VQ847_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3050602.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18528..18827
                     /locus_tag="VQ847_001259"
     CDS             18528..18827
                     /locus_tag="VQ847_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3050603.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18844..21636
                     /gene="infB"
                     /locus_tag="VQ847_001260"
     CDS             18844..21636
                     /gene="infB"
                     /locus_tag="VQ847_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3050604.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21887..22237
                     /gene="rbfA"
                     /locus_tag="VQ847_001261"
     CDS             21887..22237
                     /gene="rbfA"
                     /locus_tag="VQ847_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3050605.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         6598 a         3881 c         4889 g         6967 t
ORIGIN      
        1 tatctacaac ctcaaaacag tgttttgagc tgacttcgtc agttctatcc acaaccttaa
       61 aacggtgttt tgagcagtct gtgcctagct ttctagtttg ctttttgatt tttattgagt
      121 atgagttacc taaattatga tgcatagttg atgggatata tataatagat tgaaatagaa
      181 tatgaacaaa ttgataagag gattttaaag taatctctaa caatgcttta gaaactatag
      241 tgtgctattc taaattcaat tcactataac ttgtttacgt tttaaaaaag agccgggggg
      301 ctctttttac ttatcttcag ttccctgcat ttcttttatc acagctagtc tagtctggat
      361 atccttttcc aagaccttaa acttgtaagt caagtcttct tggtattcct tgataagttc
      421 tttttgctgg ttaatgattt gcaggctgtt ttggataata tccacatcgt ccttgatagc
      481 ttgaacgcgg tcagtggtat tcaagacttc atctgtgatg gtttggcgat tttttgtaac
      541 cagataactt ccggctgcag ctcctgcaaa tagcagtagg ttggataatt tcatagcaac
      601 tccttaagcg tttttgatgg tttcagcgac ttgagcaagt ttgtcaaagt ctggttcgtg
      661 ggcgataaaa tcaatcttga ggtcatcgtc agcactgtag cgaggcacaa ggtgaacgtg
      721 agtatgaaaa actgtttgac cagcgacttc ttcacagttg gaaatgatat tcataccagc
      781 agccttagtg actttcatga ctttttgagc tacttttggt acttgggcaa agagttggct
      841 ggcgctcgta gcatccatct ccaaaagatt gcgatagtgt tcttttggca cgaccaaggt
      901 gtgtcctagt gttacttgag agatatcaag aaaggcaagg acctgctcat cttcatatac
      961 ttttgaagca ggaatttccc ctgcgatgat tttacaaaaa atgcaatctg acataaaatc
     1021 tacctctact gtactgaatt ttgatataat atagctacat tataccagat ttggagaaaa
     1081 tatgttagaa attaaaaacc tgacaggtgg ctatgttcat gttcctgttt tgaaagatgt
     1141 gtcctttact gttgaaagtg ggcagttggt cggtttgatt ggtctcaatg gtgctgggaa
     1201 atcaacgacg atcaatgaga ttatcggtct gttggcacct tatagtggct ccatcaatat
     1261 caatggcctg actctgcaag gagatgcgac tagctaccgc aagcagattg gctacattcc
     1321 tgagacgcct agtctgtatg aggaattgac cctcagagag catatcgaaa cggttgctat
     1381 ggcttacggt attgagcaaa aagtggcttt cgaacgagta gagcccttgt taaaaatgtt
     1441 ccgtttggaa cagaaattag actggttccc tgttcatttt tcaaaaggga tgaagcagaa
     1501 ggtcatgatt atctgtgctt ttgtggtgga tccaagtctt ttcatcgtgg atgagccttt
     1561 ccttggtctt gatccgctgg ctatttctga tttgattcag cttttggaag tggagaagca
     1621 aaagggcaag tctattctca tgagtaccca cgtgctggat tcggcggaga agatgtgtga
     1681 tgcctttgtc attcttcaca agggagaggt gcgtgccaaa ggcaatctcc tgcaactacg
     1741 tgaagccttt gatatgcctg aggctagttt gaatgatatt tacttggctc tgaccaaaga
     1801 ggaggatcta tgaaagactt gtttttaaag agaaagcagg cctttcgtaa ggagtgtctt
     1861 ggttatctgc gctatgtgct caatgaccac tttgtcttgt tcctgcttgt cctgttgggc
     1921 tttctagcct accagtacag tcaactctta caacattttc ctgaaaatca ttggcctatc
     1981 cttttgtttg taggaattac gtctgtttta cttttacttt ggggaggaat tgccacctat
     2041 atggaggctc cagacaagct ctttctctta gttggagaag aggaaatcaa gctccatctc
     2101 aagcgtcaaa ctggcatttc cctagtcttt tggctctttg tacagaccct tttcttgctg
     2161 ttatttgcgc ccttgttttt agcaatgggt tatggcttgc cagtttttct gctctatgtg
     2221 cttttattgg gggtaggaaa atatttccac tttcgtcaaa aggccagcaa atttttcact
     2281 gaaactggac tggactggga ctatcttatt tctcaagaaa gcaagcgtaa gcaagtcttg
     2341 cttcgtttct ttgccctctt tacgcaggtc aagggaattt caaacagtgt caagcgtcgt
     2401 gcctatctgg actttatctt aaaggctgtt cagaaggtgc ctgggaagat ttggcaaaat
     2461 ctctatctgc gttcttatct gcgaaatggc gacctctttg ctctcagtct tcgtcttctc
     2521 ttactttccg tactggcgca ggtttttatc gagcaagctt ggattgcgac agcagtggta
     2581 gttctcttta actacctctt gctcttccag ttgctggccc tctatcatgc ctttgactac
     2641 cagtatttga cccaactctt tccgctggac aaggggcaaa aggaaaaagg cttacaggag
     2701 gtagttcgag gattgaccag ttttgtttta cttgtggaag tagttgttgg gttgattacc
     2761 ttccaagaaa aactagccct tctagcctta ctaggagctg gtttggtttt actagtcttg
     2821 tatttgcctt atcaggtaaa acgtcagatg caggactaac attgctgata cgacactaaa
     2881 aaagaagttg agttcagtct gtctcaactt cttttttgtt actacaggat aatggttggt
     2941 ccgtagagac ttatactctt cgaaaatctc ttcaaaccac gtcagcgtcg tcttaccgta
     3001 ctcaagtaca gcttgcggct agcttcctag tttgctcttt gattctcatt gagtattaac
     3061 ttggtcttga cttggtcaaa gtggaagcgg tcataggccc gccaagcggc gcgagttgga
     3121 gcatctggat caagagcgct gagtcccatg agaagactgg aagtctggta aaatttttcc
     3181 aattcaatca agaatcgatt atccactgtt tcagccttgg ctagaaaacc aagaatagag
     3241 tttaattgct cctgaaagcg gacgtcgtca gcggttgcct gtttgcatgc ttgataggct
     3301 ttgtttaagt cagtaatcaa agtctgagct cttttgatag ggtctgtatc tgtcatgaga
     3361 attcctcctc taatctgggt gccagtcttg attctagcaa ctgtgttttg atactgtcag
     3421 tctatcactt ttatctcctt tttcgccttt aaatctttaa ttgtcattga aatgtcttga
     3481 attgcgctga gtgaatttta tgataaaata gtggtaagct catcatgata ttgtagaaaa
     3541 ataattcttt taggagcttt caaagactgt ttaggattgg gtgtgcttgt gttagatttt
     3601 ttctgttatt cttttcttag gaggagaatc caatgaaaca tatgattatt cagacacaga
     3661 aaacagtcta taaagtaaac gtcgacgatg tctactatat ccaaacacat ccaactaaag
     3721 cccatactgt aaagattgtt acagaagagg ctagttttaa tatggttcaa aatttaagta
     3781 atcttgagaa ccaatatggg gaaaccttga tgagatgtca tcgaaattgt ttggtcaatc
     3841 ttgataaagt aaaatcgatt gattttcaag aaagaatcct ttttcttgga gaagaaggtc
     3901 aatacgctgt caagtatgcc agacgtcgct atagagaaat tcgtcaaaaa tggttgaaag
     3961 aaggagagta agaagatgag aatatttgtt ttagaagatg atttttccca acagactaga
     4021 attgaaacga cgattgagaa actcttgaag gaacatcata tcactctgag ttcttttgaa
     4081 gtttttggta agccagatca attgctggca gaggtgcatg agaagggggc ccatcagcta
     4141 ttctttttgg atattgagat tcgaaatgag gagatgaagg gtctggaagt ggctagaaag
     4201 attcgggatc gggatccgta tgccctgatt gtctttgtga cgactcactc ggagtttatg
     4261 cccctgtcct ttcgctacca agtgtctgct ctggattata ttgataaggc cctttcggca
     4321 gaggagtttg aatctcgtat cgagacagcc ctcctctatg ccaatggtca agacagtaaa
     4381 agtctagcgg aagattgctt ttactttaaa tcaaaatttg ctcaattcca gtatcctttt
     4441 aaagaggttt actatctcga aacgtccaca agaccccatc gtgttattct ctataccaag
     4501 acagacaggc tggaatttac agcgagtcta gaggaggttc tcaagcagga gcctcgtctc
     4561 ttgcagtgcc atcgctcttt tctcatcaat cctgccaatg tggtgcattt agataagaaa
     4621 gaaaaactgc ttttctttcc caatggtgga agttgtctaa tcgcgcgtta taaggtcagg
     4681 gaagtgtctg aggctattaa taacttacac tgagctagga gagtttatga atgttgcttg
     4741 gatattgttg tatacacttg ttactcacgg attaaaaatt gtcatattct ttaaggtaga
     4801 tggaattagt ctcacttttg agaggatttt taaggccttt ctttttaaga tactgttggc
     4861 cgttgttttt ggaatgcttg gctatatggt aggaaatgtt tacctatctt attttatgga
     4921 acccttgtac ggcataggct tatctttctt attgttaaga gaacttccta aaaaactcct
     4981 tctcttttat ggtctctttc caatgatatt agtgaatctc ttttatagag gtgtttccta
     5041 ttttgtgctt ccatttttgg gacaagggca agtatatgat gactactcat ttatttggtt
     5101 atgtataata attttcaatt tcttcatttc tctagctttt ttgaaatggt tggactatga
     5161 tttcactagc ttgagaaagg ggattctcga taaagatttt caaaagtccc tgactcagat
     5221 taactggata atgggggctt actatttggt gatacaaaat ctgtcttact ttgaatatga
     5281 acaggggatt caatcaacga ctgttcgcca tctcatccta gtcttttacc tgctcttttt
     5341 tatggggatt atcaagaaat tggataccta tttgaaggac aaactccatg agagactgaa
     5401 ccaagagcag gacttgcgct acagagagat ggagcggtat agtcggcata tagaggagct
     5461 ttataaggaa gtacggagtt ttcgccatga ctacaccaac ctcttgacta gcttacgtct
     5521 gggcattgaa gaggaggata tggagcagat aaaagagatc tacgactcgg tcttaaagga
     5581 ttctagtgaa aaattgcagg acaataaata tgaccttggc cgattggtga atgttcggga
     5641 tcgtgccctc aaaagtctcc tagctggaaa atttataaaa gctagagata agaacattgt
     5701 ctttaatgtc gaagttccag aggagattca ggtagagggg gtgagtctac ttgattttct
     5761 aaccgttgtg tctatccttt gtgacaacgc tattgaagct agtgtagaag cctgtcaacc
     5821 tcatgtttca attgcctttt ttaaaaatgg agcacaggag acctttatca ttgaaaattc
     5881 catcaaagaa gagggaatcg atatttctga aatcttctcc tttggagcaa gttctaaagg
     5941 ggaggagaga ggagttggtc tctataccgt tatgaaaatt gtggaaagtc atcccaatac
     6001 cagtctcaat accacctgcc aagatcacgt ttttcgtcag gtacttactg taatacatat
     6061 agaatgaaga aaaaataaga ccgagagtgc gttctcttgg tcttgttttt ttatagttgt
     6121 attggctgat aaaatccttt tgtatttttt tgttcaatta tattaaatct atataagaaa
     6181 tcttcccacc atcctccacc tataatttgg ttgagttcgg tagttgttag ttcttgaaat
     6241 gaagttaggt tttgtttctt atccatgtta tgattctcct ttttgataag ataataaata
     6301 gttatagagt gttatctgaa aattaatcag aatgggttaa aattttatct ttgaaataat
     6361 caaaatatgt tttctttgta gttacactag tgacgcgacc ttgtaagcca tattggatga
     6421 gtttactatc ctcgttagat agttttgcaa gagcggttaa tttaaagaga ttgccttgct
     6481 ctgttctggt aggagtttga tcaatactct gaagttggcc gatgatggtg gtgccgtgat
     6541 ttccaatctt ctccagtttt aatcttacag tttgtccttt atctagtaag gggagatagt
     6601 cagatgatac gtagtaagtg attagtactt ctcttgtatc tgtgatgaca gggaatattt
     6661 gagcaatttc tgtaccagtt ggaattctat ttttaccttc aaattcgctg ttcagatgaa
     6721 cgataccttt acttggagcg gttaaggtat tattttctaa gcgctgtgtc gcttgatcta
     6781 gttgtacttt taattctgtt aattgattct ccacggttag ttgttgctgt gaggctgttt
     6841 gtaaaaactg agtgcggagt acttcaattt tggttgctaa actattatca taagttgcta
     6901 cacttccgat accagcttgc tgaattttga tgcttgcgat agatgattca agacttgcaa
     6961 tactttgatt aatttgagat aaaaatggct cctctgccgt tccttgtgtt tgtccttgag
     7021 aggctataag ataacgattt aaaattgact ggtgcggatt gccagttggt aagcgtgctc
     7081 tgttatttat gatagcatct ctcaactctt gatattctcc aatttgttgt tgaacttttg
     7141 taatttcttg ttcgatggct gatgaactgc tattggtaag attagcttga tttgaaactt
     7201 cagtgttagt ctttgagata cccagttcaa tatcatggga ttgtttagta aaattcataa
     7261 aggtattatg gtagccaaac tcatcctcgc tagaaaaaag atcagtcgct ttttctaagc
     7321 tttgtttcaa gattccaagt ccttcttttt gcttctcaag tctttgtaat tgagttgcta
     7381 aggcagtttt ctgactttct tccattgttt cagagtattt gatgagtaag tcacctttct
     7441 caactacttg atttgccact aaatgattag caaggatagg attatcactg gtcgactgaa
     7501 tagatgcaat gacacttgta ggggcgattt ctccttggga agtaacagta atttcttttg
     7561 tggcaacaag ggagaaaatc aagatgaaag taaatagtaa tgaaaaaggt ataatgaaca
     7621 ctgtcgcata gttatggtaa cgtctctgat aaaactcgac acttctaaaa agattaggat
     7681 tcatgacatt ctccttattt attgaataga tgatggtaga agccttgcgc ctgcattaac
     7741 tcttggtgac taccaacttc aatgattttc ccctggtcaa gaacaatgac acggttagtt
     7801 cgttcggcta tactgagacg atgggctaca aagagaatgg ttttatcagt tagggatata
     7861 agattatcta taaccttttt ctcagtcaag acatcaagac cgctagtagc ttcatctagt
     7921 attaaaacag gagctttagt taaaagagca cgagcgagag cgattcgttg cttttgtcct
     7981 cctgatagac cagctccatc agagagctga gtttgatagc ccataggcat tctttcaatg
     8041 tcttgacgga tttcagctaa ttcacaagct cttagaatat cttcttggct aatcatatga
     8101 ttaccgccca aggttaaatt ttccaagata gagccattaa agatataggc ttgttggggt
     8161 aggtaattaa tatgacggcg caagactttt ttatcaatgt ttttaatatc ctgataattg
     8221 atggaaatat gccctttgta gggttcaaag aaattgacaa tcattttggc taaagttgtt
     8281 ttaccagaac cactaactcc aactaggcta accttatctc cttgtttaat cgtgagatta
     8341 atatctgtta aggtatctcg tccaaaacca tacttataag aaaggtcatc aaattcaata
     8401 tcgcccatca aaaaatgtga atgaacaggg ttttcttgaa cttgaaattc agattcgact
     8461 agatagactt cgttcaaacg gttattagcg accttcgcag attggagttt ggtttggagg
     8521 ttgataatat tttccatagg agttgtaaag taagaaaaaa gtgtgttaaa ggtaatcagc
     8581 tgaccgatag aaattttact cgacatgact aattgagcgc caaaccatag gataaggata
     8641 ttcagaacta attttgttcc ctgctttaaa ctcgtttgta aaatagaata tttactgagc
     8701 ttaaaggatt tttccaaata atctacaaat tcgctgtcta tattttgata gcgattttct
     8761 tcactcgtga gcgactttat agtttcaatc ccgttgatat cttcgataat ggcagagcta
     8821 accatagaat tactttgcat gacatcatgg ttcatttttt cgaaaggttt cataaaagaa
     8881 aagatgatga acatgtatat aggaatggaa agaagagaaa ggaggaagag attagggttt
     8941 tgtgccagta agacgccccc tacaagaatc agaatagaaa catccagaaa aagagaaaga
     9001 atggtagaag ccaaggcatc tataatagag ttagcatctg tgaaccgtga aatgatttct
     9061 cctgtacgac gtgtcgcaaa gaaagacatg ggaagttcaa aaatatggcg aatataggat
     9121 aaaatcacat caatgcttaa tctctggctc agaacggtta ggagataatc tctggaaaag
     9181 ctcatgactt gttggaggat ataggtgata accagaccaa ctgagatgat tcctaaagtt
     9241 gatttcatct gatttgggat gtattcatcc aagattcctt ggagataata agaaccaccg
     9301 atattgataa tagtgaccaa taagcttgag agaacaatgt aagcaatgag agatttttgt
     9361 ttgaaaatca gaggaaggaa gcttagtaga ccattctttt tatctttatg gggttgatag
     9421 ctgggtttgg gagctagaaa aatagctact ccagtccatt cagagaaaaa gcgttctttt
     9481 gacattttag tgatttttac agaagggtca ggatcaccaa taatcagata gtctttcttt
     9541 gtttgataga caacatagta atgttggagt tttccttctt tgttaacgtg aacgataaat
     9601 ggatagggga catcactcat gtcaaagaga gttttatctg cttgaacagg ccttgtttca
     9661 aagcccattt catcagcggc ttttacaatg ccaagagcag tcgtcccttc tttattggtc
     9721 tttgcaagtt ctctcaagtg agctagagaa aaatctgaac catagaattt agcaatcgag
     9781 gctaaggcag caacaccgca gtctctagca tctatttgag gaacaaatgt acgtttataa
     9841 gaagtcattg gcaattcctt tcatatagtg gatagctcta ttatgacata aaaacaattt
     9901 cgtgctttat aaaatcttga atagtcattg aaatttcctg aatggtaaaa aagtgattag
     9961 aaattatctt ttaaaaaaaa tttagaggta gttttaaata aaaaagctaa tttaagacgt
    10021 ttcgatgaca attcaagatt tggatgaaaa actttaacaa atagtgctat actaaacttg
    10081 tcaaagttgc aacaagacaa aaattaaaaa taaaaaagga gtatttgtta tgaatacaaa
    10141 aatgatggaa caatttcatg aaatggatat agctatgtta tctagtattg aaggaggcaa
    10201 gaataattgg caaactaatg ttttcgaagg tggtagtgct gcttttggtg gctgggggtt
    10261 agggacagct atttgtgctg cgagtggtgt tggagcgcca tttatgggag catgtggata
    10321 cataggagct aaatttggtg tggctctttg ggcaggagta acaggggcaa cgggtggatt
    10381 ttaacaaaag gagacttgta tgaatactta ttgtaatata aatgaaacaa tgctgagtga
    10441 ggtttacgga ggtaattccg gaggagcagc tgtagttgct gctttaggtt gtgcagcggg
    10501 tggagtgaaa tatgggaaaa ttctaggacc atggggcgct gcaataggag gaattggagg
    10561 agcagtggtt tgtggatatt tagcctatac cgctacatca taaaaatgaa agctaaattt
    10621 tatgaaggct atattcttta ttattctctt cgcttttcaa acctatctta tttatctatc
    10681 cataagtatc tctgataaaa aacaaaagac tattgaatta acatcattga attgttttgt
    10741 catattattt ctaatctatg ataaattaat ttttctcttt attgcctatg tttttttgat
    10801 aatttttata ttaaacttgt tccgtaactg aaaagtgaca tactatatga atacaaaaat
    10861 gatgtcacaa ttttctgtta tggataatga aatgcttgct tgcgttgaag gtggagatat
    10921 tgattgggga agaaaaatta gttgtgcagc aggggttgca tatggcgcaa ttgatgggtg
    10981 tgcaacaacg gtttgacatt tctattggga ccatttgcta taggaatagg tgtaactggt
    11041 gctgcaggtg gagctatact tggaggtgta gcctatgcag caacatgttg gtggtaatta
    11101 tggattttaa aagttttatt attggtttag tagttggtat atttggtcct tatatggatg
    11161 acttaattag aaaaatattt tcaaaatctt ccaaaaagga tacggatagt actctctaaa
    11221 aaataaattt ctcccctgta tttgctagct taatttacag gggagtttct ttaatattgt
    11281 ttcgcctgtc aaaatgatat gtgatagcag gatgaaaagt ctacaaacaa gttggtatca
    11341 atacaatata aagaggaaag tatgtttttc atgcttgctt ttttaatttt tacaattcaa
    11401 gaggttttga tgaccattta tgatttgagt gatccaaggt caaaataagt gctatactag
    11461 cagtgtaaat gttcttgctc aactaagata aatcgcacat ttaggaggaa atcttatgaa
    11521 gaaaaaaata ctgattattt tcgttctgta tctgatcatg tccatctttc tttatccgct
    11581 tagggagagt atttggtata atctatttta taccatagcc tatatgattg cggttatgat
    11641 ctatttttct ttaattaaaa agaaagaaaa gaaatgaaag attttcttga ttaaaaagaa
    11701 tcatattctt tgtgagattg ttcctgggtc agttgccttt gcttgtttct acttatctat
    11761 ttctatttcg tcagttttcc aatttctttt agtggttatt aacttagctt ctattttggt
    11821 cactgtttac ctcactaggg aaatgcggat aaaagagttt gaagatgatg atttggttag
    11881 tcctagaacc aatcaactta tgttcatcgg cttgacaggc tttatgtcta ttatttgttt
    11941 gtatagaggg atcacagcag gagaatccta ccaacaaata atcgcttata ttggcgctat
    12001 tctctgcttg accatcatgc ttctgctcat ttggggattg aagtattata aaaagtagag
    12061 gctaatgcag tttttgcaat ttaagatgtc ttgatgacaa ttcaagattt ggatgaaaaa
    12121 ctttgacaaa tagtgctata ctgaaattgt caaagttgca acgggtgctg ctacattatg
    12181 ttaaaaatcg ctcttgattg ataagttgga tttgttagga aaggagtaaa taattatgga
    12241 taagaaaaag atagtttcga ctataatatg tatagtattt cttgtagtgt cagtagataa
    12301 tttttttaga gacttaaccc cgttactgtt cattttaaat attattggcc tgtcttgctt
    12361 ttcagtgcta acatacatta acataaaaga gatactctta aatataagta aatgatgatt
    12421 tggttagtcc tagaaccaat caacttatgt ttatcggctt ggcagatttt atgtttgtca
    12481 tttgtttgta tagaggtatt tcagaaacag aattctatca acaactaatc gcttatatag
    12541 gtgtattctc tgcttgttta tcacgcttct gctcatgtgg ggcttgaagt attataaaaa
    12601 gtagctttct atccttttct gacaggatat ttgagtagaa ggctctatta aattgttagt
    12661 gaaataaatg aatggaggta tttaatatga aatacagatt attttttgtt attttcttga
    12721 gtagtgtgtt ggatattctt ttagggacat ttttacaaat ctctatcgta tctattgggt
    12781 ggcttgttct ttacagtggt ttgtttgaag caggagtttt ccttcttgct aataaagggg
    12841 tggcggtaaa aatcaaggaa gtagatattc gaaatcgctt taaatttatt tttggaaaaa
    12901 ccttatggtt tcaaattctt ttgctcatct ttttgataat caaactttat cttggtttgg
    12961 atgcgaggtt gattttattc tatggacata ttttcattgt ctttaatgcc ttaatgtatc
    13021 tattatctag tagtcaggtt agccttaaaa aaaacaaact gtcttcttaa tcttacagca
    13081 gtagagcctg acaaggtgag gtcatagtag ggaggatttc tatgaaaaag tatcaacttc
    13141 tattcaaaat aagtgcagtt ttctcttact tatttttcgt atttggtctt tctcagatga
    13201 cgcttattat tcaaaattat tggcaatttt cttcccagat tggcaatttc gtctggattc
    13261 aaaatttctt gagtttgcta tttagcggag tcatgatttg gattctggtt aagacaggtc
    13321 atggttatct ctttcacatt ccaagaaaaa aatggctttg gtattcgatt ttgacagtat
    13381 tagtggtagt gctccagatc tcttttaacg ttcagacagc taaacatgtt cagtcaactg
    13441 ctgaaggttg ggctgtattg atcggttata gtgggaccaa ctttgctgag ctaggtatct
    13501 atataacttt gttctttctg actccactta tggaagagct aatctataga ggattactgc
    13561 aacacgcctt ttttaagcat tcgagatttg gccttgattt gcttcttccg tcaattttat
    13621 ttgctcttcc tcatttttca agcctgccta gtttgttaga tatcttcatc tttgcaacat
    13681 ctggcatcat ctttgctagt ttgacccgct ataccaagag catttatcct tcctatgcgg
    13741 tgcatgtgat caataatatt ttcgcaacat taccattttt gctgactttt ttacataggg
    13801 tcttggggta aaaaaacaaa aggcttgctt ttcagccata gaggagatta tcatgtataa
    13861 acacttattt ttcctagatt ccaaaacttt agatcggttg acaccctata ttctagtctt
    13921 ggcttctgac accattgctt ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt
    13981 taatttccta aattccatgc tagctttaat ggctatattc ataggggctg gctatgtggt
    14041 cggattttgg ttactaatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
    14101 gctgtacttg agtacggcaa ggcgacgttg acgtggtttg aatttgattt tcgaagagta
    14161 taaaatggtt tgttttggaa aggctagaac taaagaatga cgcgtaggaa gtctgtttgg
    14221 tgaggaggat agttttatgg agttttttga taaatttcat gccttgtgtt ttggattttt
    14281 agtactaata attgtcatta cagttcctta tacgattaac catggggttt tttttcaaaa
    14341 tgaatctgca ttgattcttg taagtcttct tgtaacctcg ctgagtgttg cttatgctag
    14401 aaagtttgaa atgatttctt ttgggatgtt aagcaagaaa caacttttgc ttttcattgc
    14461 aatctttctt ctaagtgtac ttgagacgct ggtttatatt catttcttcg ctgtttcttc
    14521 tggctcaggg gtccaacact tggcggaagt cagcagagga atttccctgt ctttgatttt
    14581 gactacctca gtttttggcc ccatccagga ggaactcatt ttcagaggac ttcttcaagg
    14641 tgcggttttt gacaattctt ggttagggct tgtgctaact tcctctctct tttctttcat
    14701 gcatggacct tctaatgtcc cttcgtttat tttttatcta cttgggggtt tgttgctggg
    14761 ctttgcttat aaaaagagtc aaaacctatg ggtttctact ctagtccaca tgttttacaa
    14821 cagttggcca ctcctatatt atttataaaa attatgaaaa ggtaagcaga agatggtgct
    14881 tacctttttc aagctataat gatacccaag ccaatccaga ggcttttctt tgagaatcgg
    14941 gttagagtgg ttgacgaata ggccaaaaac tagtagaata gtaaggaaac tttatacgga
    15001 ggaaagaaat ggatttgggt gataatgagc taacactgac tcccatacct gggaaaagtg
    15061 gcaaggctta tatgggtagc tatcctgacg ggaagcgcat ctttgtaaaa atgaacacct
    15121 ctccaatcct acctggtcta gctagagaac aaattgctcc acaattatta tggagtcgtc
    15181 gtttggcaga tgggcgtgat atgtgtgctc aagaatggtt gacaggcaag atattgaccc
    15241 cctatgatat gaatcgtaag caaatcgtca atattttaac ccgtcttcat cgctcacgtc
    15301 cgttgatgac acaattgagt cgtttgggct atgccatgga aacacctgta gatttactac
    15361 agtcttggca ggaaacggct ccagatgctt tgcgtaaaaa tcattttatc agtgaagtga
    15421 tggctgattt acgtcagact attccaggat ttagagagga ccatgcgacc attgtccatg
    15481 gagatgtacg acatagtaat tggattgaga cagatagtgg cttgatttat ttagtagatt
    15541 gggattcggt tcgcttgacc gatcgcatgt ttgatgtggc ccatatgctc tgccattata
    15601 tttcagaaca tcagtggaag gaatggttga cctactacgg ttacaagtac aatcaaacgg
    15661 tattaagtaa attgtattgg tatggtcaat tgtcttattt gagtcagatt tccaagtatt
    15721 atatgaacca agatttagaa aatgtcaatc gggagattca tggtttgcgt catttccgag
    15781 acaagtatgg aaagagaaga tgagagttag aaatcgtaaa ggggcaacag aattactaga
    15841 ggcaaatccc cagtatgtgg tcctcaatcc cttggaagcc aaggcaaaat ggcgggactt
    15901 gtttggcaat gataatccca ttcatgtgga agttggaagt ggaaagggtg cctttgtttc
    15961 aggtatggcc aagcaaaacc ctgacatcaa ctatatcggg attgatattc aaaagtctgt
    16021 tttgagctac gctttggaca aggtgcttga agttggagtg cctaacatca agctcttgtg
    16081 ggtagatggt tctgacttaa ctgactactt tgaagacggt gagattgatc gcttgtatct
    16141 gaacttttca gatccatggc cgaaaaaacg ccatgaaaag cgtcgtttga cctacaagac
    16201 cttcttggat accttcaaac gtatcttgcc tgaaaatgga gaaattcatt tcaagacgga
    16261 taaccgtggc ttgtttgagt acagtttagt gagcttttct caatatggca tgaaactcaa
    16321 tggtgtctgg ttagatttgc atgccagtga ttttgaaggc aatgtcatga cagaatacga
    16381 gcaaaaattc tcaaacaagg ggcaagttat ctaccgagtt gaggcagaat tttaagagat
    16441 agcctaaaat taggctgtac aagtgctttt gctttacata agttggcaaa cgtgctatac
    16501 tgatagtaag aatatgaaaa gtgaggcggg gaaatatctt cgcctcttgc ttatgaggag
    16561 gtggacgcaa tcgcaacaat cgtagaatta gtcagagaag ttgtagaacc tgtcatagaa
    16621 gctccttttg aactcgtgga tatcgagtat ggaaagattg gcagtgacat gattctcagt
    16681 atttttgtag ataaacccga aggaattacc ttgaacgaca cggcagactt gacagaaatg
    16741 atcagtcctg tcctagacac catcaagcca gatcccttcc cagaacaata tttcctagaa
    16801 attaccagtc caggtttgga acgtcctttg aaaaccaagg atgccgtcgc tggagcggtt
    16861 ggaaaataca tccatgtcgg gctctaccaa gccatcgata agcaaaaggt ctttgaagga
    16921 accttgttgg ccttcgaaga ggacgagttg actatggaat atatggacaa gacgcgtaag
    16981 aaaaccgtcc aaattccata cagtttagta tcaaaagcac gtttagcagt taaattatag
    17041 aaaaagaaag gatagctttt gaggattcaa aagtgaagaa aacatgagta aagaaatgct
    17101 agaggccttc cgcattttgg aagaagacaa gggaatcaaa aaagaagata tcatcgacgc
    17161 agtagtagag tcgcttcgtt ccgcttatcg cagacgctat ggtcagtcag acagcgtagc
    17221 tattgacttc aacgaaaaaa caggtgactt tacagtttat actgtccgtg aagttgttga
    17281 tgaagtattt gatagccgtt tggaaatcag cttgaaagat gctcttgcca ttaattcagc
    17341 ttatgaactt ggagacaaaa tcaagtttga agaagcacca gctgagtttg gtcgtgtagc
    17401 agcccaatct gccaaacaaa ccatcatgga aaaaatgcgc aagcaaacac gtgccatcac
    17461 ttacaatact tacaaagaac atgagcaaga aatcatgtct ggtacagtag aacgctttga
    17521 caaccgcttt atctatgtca accttggtag catcgaagcc caattgtcaa aacaagacca
    17581 aattcctgga gaagtttttg cttctcatga tcgtatcgaa gtttatgttt acaaggttga
    17641 agacaaccct cgtggtgtga acgtctttgt tagccgtagc catccagaaa tgatcaaacg
    17701 tttgatggag caagaaattc cagaagttta tgatggaact gttgaaatca tgagcgtggc
    17761 tcgtgaagca ggtgaccgta cgaaggttgc tgttcgtagc cacaatccaa acgtggatgc
    17821 tatcggtaca atcgttggac gtggtggtgc taatatcaag aagattacta gcaaattcca
    17881 cccagctcgt tacgatgcta aaaatgaccg catggtacca atcgaagaaa atatcgatgt
    17941 tatcgagtgg gtagcagatc cagctgaatt tatctacaat gccatcgctc ctgctgaggt
    18001 tgaccaagtt atctttgatg aaaacgacag caaacgtgcc ttggtggttg ttccagataa
    18061 caagctttct cttgccattg gtcgtcgtgg acaaaacgtg cgcttggcgg ctcacttgac
    18121 tggttaccgt atcgatatca agtctgctag cgaatttgaa gccatggaag acgctgcttc
    18181 agtagagttg gaagtagaaa acgatactgt agaagaataa aagctgctag aggagggaaa
    18241 gatgaaaaca agaaaaatcc ctttgcgcaa gtctgttgtg tctaacgaag tgattgataa
    18301 gcgtgatttg ctccgcattg tcaagaacaa ggaaggacaa gtctttattg atcctacggg
    18361 caaggccaat ggccgcggcg cttatatcaa actagacaat gcagaagccc tagaggcgaa
    18421 aaagaagaag gtctttaacc gcagttttag catggaagtg gaagaaagct tttatgacga
    18481 gttgatcgct tatgtggatc acaaagtgaa aagaagagag ttgggacttg aataagcaaa
    18541 agataagtaa tctcttgggg cttgctcagc gagcagggcg catcatatcg ggtgaagaat
    18601 tggtggtcaa ggccattcaa gacggcaagg ccaagttggt ctttctagct catgatgctg
    18661 gacccaatct gaccaagaag attcaagata aaagtcatta ttatcaagta gaaattgtaa
    18721 ccgtgttttc aacactggaa ttaagcatag cagtcgggaa atcgagaaag gttttggctg
    18781 taacagatgc tggatttaca aagaaaatga ggtctcttat ggaatagaag aggaggacat
    18841 gatttgtcta agaaaagatt gtacgaaatc gcaaaagaac ttggaaaaga aagtaaagaa
    18901 gttgtagcgc gtgcaaaaga gttgggcttg gatgtgaaaa gccactcatc aagtgtggaa
    18961 gaagctgtcg ctgcaaaaat tgctgccagc tttaagcctg cagctgctcc gaaagtagaa
    19021 gcaaaacctg cagcaccaaa agtaagtgca gaaaagaaag ccgaaaaatc tgagccagct
    19081 aaaccagctg tagctaagga agaggcaaaa ccggctgagc cagttgctcc gaaaacagaa
    19141 aaagtagcag cgaaaccgca aagccgtaat ttcaaggctg agcgtgaagc ccgtgctaaa
    19201 gagcaggcag aacgacgcaa gcaaaataag ggcaataacc gtgaccaaca acaaaacgga
    19261 aaccgtcaga aaaacgacgg ccgtaatggt ggaaaacaag gtcaaagcaa ccgcgacaat
    19321 cgtcgcttta atgaccaagc taagaagcag caaggtcagc aaaaacgtag aaatgagcgc
    19381 cgtcagcaag aggacaaacg ttcaaatcaa gtggctccac gtattgactt taaagcccgt
    19441 gcagcagccc taaaagcaga gcaaaatgca gagtacgctc gttcaagtga ggaacgcttc
    19501 aagcagtatc aggctgctaa agaagccttg gctcaagcta acaaacgcaa ggaaccagag
    19561 gaaatctttg aagaagcggc taagttagct gaacaagcac agcaagttca agcagtggtt
    19621 gaagtcgtcc ctgagaaaaa agaacctgca gtggatacac gtcgtaaaaa acaagctcga
    19681 ccagacaaaa atcgtgacga ttatgatcat gaagaagatg gtcctagaaa acaacaaaag
    19741 aatcgaagta gtcaaaatca agtgagaaat caaaagaata gtaactggaa taacaacaaa
    19801 aagaacaaaa aaggcaataa caagaacaac cgtaatcaga ctccaaaacc tgttacggag
    19861 cgtaaattcc atgaattgcc aacagaattt gaatatacag atggtatgac cgttgcggaa
    19921 atcgcaaaac gtatcaaacg tgaaccagct gaaatcgtta agaaactttt catgatgggt
    19981 gtcatggcca cacaaaacca atccttggat ggggaaacaa ttgaactcct catggtggat
    20041 tacggtatcg aagccaaaca aaaggttgaa gtggataatg ctgacatcga acgtttcttt
    20101 gtcgaagatg gttatctcaa tgaagatgaa ttggttgagc gtccaccagt tgttactatc
    20161 atgggacacg ttgaccacgg taaaacaacc cttttggata ctcttcgtaa ctcacgtgtt
    20221 gcgacaggtg aagcaggtgg tattactcag catatcggtg cctaccaaat cgtggaaaat
    20281 ggtaagaaga ttaccttcct tgatacacca ggacacgcgg cctttacatc aatgcgtgcg
    20341 cgtggtgctt ctgttaccga tattacgatc ttggtcgtag cggcagatga cggggttatg
    20401 cctcagacta ttgaagccat caaccactca aaagcagcta acgttccaat catcgtagcc
    20461 attaacaaga ttgataaacc aggtgctaac ccagaacgcg ttatcggtga attggcagag
    20521 catggtgtga tgtcaaccgc ttggggtgga gattctgaat ttgttgaaat ctcagctaaa
    20581 ttcaaccaaa atatcgaaga attgttggaa acagtccttc ttgtagctga aatccaagaa
    20641 ctcaaggcag acccaacagt gcgtgcaatc ggtacggtta tcgaagcgcg cttggataaa
    20701 ggaaaaggtg cggtcgcaac ccttcttgta caacaaggta ccttgaatgt tcaagaccca
    20761 atcgttgtcg gaaatacctt cggtcgtgtc cgtgctatga ccaacgacct tggtcgtcgt
    20821 gttaaagttg ctggaccatc aacaccagtc tctatcacag gtttgaacga agcaccgatg
    20881 gcgggtgacc actttgccgt ttacgaggat gaaaaatctg cgcgtgcagc aggtgaagag
    20941 cgtgccaaac gtgccctcat gaaacaacgt caagctaccc aacgtgttag ccttgaaaac
    21001 ctctttgata cccttaaagc tggggaactc aaatctgtta atgttatcat caaggctgat
    21061 gtacaaggtt ctgttgaagc cctttctgcc tcacttcaaa agattgacgt ggaaggtgtc
    21121 aaagtgacta tcgtccactc agcggtcggt gctatcaacg aatcagacgt gacccttgcc
    21181 gaagcttcaa atgcctttat cgttggtttc aacgtacgcc ctacaccaca agctcgtcaa
    21241 caagcagaag ctgacgatgt ggaaatccgt cttcacagca ttatctacaa ggttatcgaa
    21301 gagatggaag aagctatgaa agggatgctt gatccagaat ttgaagaaaa agttattggt
    21361 gaagcggtta tccgtgaaac cttcaaggtg tctaaagtgg gaactatcgg tggatttatg
    21421 gttatcaacg gtaaggttgc ccgtgactct aaagtccgtg ttatccgtga tggtgtcgtt
    21481 atctatgatg gtgaactcgc aagcttgaaa cactataaag acgacgttaa ggaagttaca
    21541 aacggccgtg aaggtggatt gatgatcgac tgctacaatg atattaagat ggatgatgtg
    21601 attgaggcgt atgtcatgga agaaatcaag agataagatt ttttgctcct ttcttaggtg
    21661 gtgagggacg caagcaaacc gatggtttca ttgcttattt ttgagcctag ggtctcaaaa
    21721 atcccctgtg atgggactga taaatcagtt ccatcacttt caccacggcg aaagaagcag
    21781 atgacttcaa attgaacttc gtttcaattt aaactgaaaa tcaagaagtt taaaatagct
    21841 aggtctgctg gcctagcttt tggttcaaag tagagaaagg aatatcatgg caaatcattt
    21901 ccgtacagat cgtgtgggca tggaaatcaa gcgtgaagtc aatgagattt tgcaaaagaa
    21961 agtccgtgat ccacgtgtcc aaggtgtgac catcacagat gttcagatgc tgggtgactt
    22021 gtctgttgcc aaggtttatt acaccatttt gagtaacctt gcttcggata accaaaaagc
    22081 ccaaatcggg cttgaaaaag caactggtac catcaaacgt gaacttggtc gcaatttgaa
    22141 attgtacaaa atcccagatt tgaccttcgt caaagacgag tccatcgagt atggaaacaa
    22201 gattgacgag atgctacgca atctggataa gaactaaaga agaggggttg cccctctttt
    22261 ttggtggagg aaaataggtt gaatttgaaa tggaaaaata ttcttttata atagtttgaa
    22321 actagaatag tacgc
//
LOCUS       DAVBNN010000031        21874 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBNN010000031 DAVBNN010000000
VERSION     DAVBNN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.031"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(408..1604)
                     /gene="tuf"
                     /locus_tag="VQ847_001262"
     CDS             complement(408..1604)
                     /gene="tuf"
                     /locus_tag="VQ847_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3050606.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2480..3349)
                     /locus_tag="VQ847_001263"
     CDS             complement(2480..3349)
                     /locus_tag="VQ847_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3050607.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3572..4252)
                     /locus_tag="VQ847_001264"
     CDS             complement(3572..4252)
                     /locus_tag="VQ847_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3050608.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4210..5316)
                     /locus_tag="VQ847_001265"
     CDS             complement(4210..5316)
                     /locus_tag="VQ847_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3050609.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5427..5681)
                     /locus_tag="VQ847_001266"
     CDS             complement(5427..5681)
                     /locus_tag="VQ847_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050610.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6039..6572)
                     /locus_tag="VQ847_001267"
     CDS             complement(6039..6572)
                     /locus_tag="VQ847_001267"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3050611.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6559..6774)
                     /locus_tag="VQ847_001268"
     CDS             complement(6559..6774)
                     /locus_tag="VQ847_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050612.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6741..6884)
                     /locus_tag="VQ847_001269"
     CDS             complement(6741..6884)
                     /locus_tag="VQ847_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3050613.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7118..8836
                     /locus_tag="VQ847_001270"
     CDS             7118..8836
                     /locus_tag="VQ847_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3050614.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8947..9294
                     /locus_tag="VQ847_001271"
     CDS             8947..9294
                     /locus_tag="VQ847_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3050615.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9572..10408)
                     /locus_tag="VQ847_001272"
     CDS             complement(9572..10408)
                     /locus_tag="VQ847_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3050616.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10421..11050)
                     /locus_tag="VQ847_001273"
     CDS             complement(10421..11050)
                     /locus_tag="VQ847_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3050617.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11060..11701)
                     /locus_tag="VQ847_001274"
     CDS             complement(11060..11701)
                     /locus_tag="VQ847_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3050618.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11847..13076)
                     /locus_tag="VQ847_001275"
     CDS             complement(11847..13076)
                     /locus_tag="VQ847_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3050619.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13066..14232)
                     /locus_tag="VQ847_001276"
     CDS             complement(13066..14232)
                     /locus_tag="VQ847_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3050620.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14376..15389
                     /locus_tag="VQ847_001277"
     CDS             14376..15389
                     /locus_tag="VQ847_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3050621.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15434..15853)
                     /locus_tag="VQ847_001278"
     CDS             complement(15434..15853)
                     /locus_tag="VQ847_001278"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3050622.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15864..17270)
                     /gene="atpD"
                     /locus_tag="VQ847_001279"
     CDS             complement(15864..17270)
                     /gene="atpD"
                     /locus_tag="VQ847_001279"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3050623.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17356..18234)
                     /locus_tag="VQ847_001280"
     CDS             complement(17356..18234)
                     /locus_tag="VQ847_001280"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3050624.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18250..19755)
                     /locus_tag="VQ847_001281"
     CDS             complement(18250..19755)
                     /locus_tag="VQ847_001281"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3050625.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19770..20306)
                     /locus_tag="VQ847_001282"
     CDS             complement(19770..20306)
                     /locus_tag="VQ847_001282"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3050626.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20306..20800)
                     /gene="atpF"
                     /locus_tag="VQ847_001283"
     CDS             complement(20306..20800)
                     /gene="atpF"
                     /locus_tag="VQ847_001283"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3050627.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20814..21530)
                     /gene="atpB"
                     /locus_tag="VQ847_001284"
     CDS             complement(20814..21530)
                     /gene="atpB"
                     /locus_tag="VQ847_001284"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3050628.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21565..21765)
                     /locus_tag="VQ847_001285"
     CDS             complement(21565..21765)
                     /locus_tag="VQ847_001285"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3050629.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6509 a         4701 c         3988 g         6676 t
ORIGIN      
        1 gatttcttct ttagttgatt tcatattact attgtataat gctttttgat ttgagtctag
       61 tattatactc ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgtcg tatagatgtt
      121 actgacttcg tcagttctat ctacaaccta aaaacagtgt tttgaacagt ctgcagctaa
      181 ctttctataa caaaatgaaa taagaacaag acaaatcaat caagacaatc aaatcgattt
      241 ctaacaatgt tttagaagta gatgtgtact attctagttt caatatatta tagtttgctc
      301 tttgattttc attgagtatt agttcaatat ctaaaaaaag aaccttgcca agcaagattc
      361 ttttagtgtc taacttaaat aattgttctt ctgggaacta aatcgaatta agcttcgatt
      421 tctgtaacca tacctgaacc aacagtacgt ccaccctcac ggatagagaa tgtagtacct
      481 tgttctacgg cgattgggtg aatcaactca acgtcgattg tcacgttatc accaggcatt
      541 accatttcag tacctgctgg aagttcgatt gaacctgtaa cgtcagtagt acggaagtag
      601 aattgtggac ggtagttgtt gaagaatgga gtgtgacgtc caccttcttc tttagtaagg
      661 atgtagactt cacctttgaa tttagtgtgt gggttgattg aacctggttt agcgataact
      721 tgtccacgtt cgatttcatc acgttgaaca ccacgaagaa ggacacctac gttatctcca
      781 gcaagacctt cgtcaagttg tttacggaac atttcaacac cagtaacaac tgctttttga
      841 gtttcttctt tgataccaac gatttcgatt tcgtcgttga ctttaacgat accacggtcg
      901 atacgtcctg aagcaactgt accacgtcca gtaattgaga atacgtcctc gactggaaga
      961 agcaatggtt tgtcagtgtc acgttctggt tctgggatat actcatcaac tgtgttcatc
     1021 aattccataa cgatgtcttc gtatttagag tcaccttcaa gagctttaag tgctgaacct
     1081 tggataactg gaagatcgtc acctgggaag tcgtattctg acaataggtc acggatttcc
     1141 atttcaacca attcaagcaa ttcttcgtcg tcaaccaagt caactttgtt catgaagacg
     1201 ataaggtgtt taacaccaac ctgacgtgaa agaaggatgt gctcacgagt ttgtggcatt
     1261 ggtccgtcag ttgaagctac tacaaggata gctccgtcca tttgagcagc accagtgatc
     1321 atatttttaa cgtagtccgc gtgtcctgga gcgtcgatgt gagcgtagtg acgtttttca
     1381 gtttcgtact caacgtgcgc agtgttgata gtgataccgc gttcgcgttc ttctggagca
     1441 gcatcgatag acgcatagtc tttaggttgg ttaactgatg aaggcaagcg acgtgccaaa
     1501 acagttgtga tagctgcagt tagggtagtt ttaccgtggt caacgtgtcc gatagtacca
     1561 atgttaacgt gtggtttact acgatcgtat ttttcttttg ccatttgagt aaaagcctcc
     1621 aataaaatat attttataga tagacagtag gcaatacagt ctaactttcc ttactatttt
     1681 atcaaatttc agctaaattg caagtgtttt acaacgtttt tgtgaattat tcttggtaaa
     1741 aatttaacta actaatagaa agtactaaat agacttatcc ttcaaggagt tttcagcatt
     1801 atccatccac tcacttgctg aaaatgtaaa cagtctctgg tttatatagt aaaatgaaac
     1861 aagaataggg caaatcgatc aggacaatca aatcgatttc taaaaatgtt ttagaagtag
     1921 aggtgtacta ttctagtttc aatctactat acaacctcaa aactgtgttt tgaacaacct
     1981 gcggctagct tcttagtttg ccctttgatt ttcattgagt ataaaattgc agataaaacg
     2041 ataacaatca taggactcag cagagtcaat gtaggtcgaa gaatagcccc cctaatcgct
     2101 tattttatag caaaatgaaa tagaaactga acattttgtt gaggaaggta aatcaattcc
     2161 tcacaatgtt tgagaaagaa gggaggacta ttccaacttc aacccactat taatatataa
     2221 tagaatgaaa actgcacaat ttgattggag aattcaaacc aatttctaac aatgttttag
     2281 aaacaagggt ctattatttc aactgcaacc tactatagcc cattgaagct ggaatagccc
     2341 actgagactt ctaaaccact gctggagagg agtttgttta gagtttcttt catttcccta
     2401 aaaaatcaaa aagagagaac cagtctgatc ctctcttact tatagatggt gctcactcaa
     2461 atgttaaagg agctatttct tagagataaa ggaatttgaa tacagctact gccgcaattg
     2521 ctgctgcgat aggtgctact actggtaccc aagaatacca ccattttgaa tcgcctttat
     2581 gctcaccaag aactgatttt ggaaggaaag catgaaggag acgtggtccc aagtcacggg
     2641 ctgggttcaa ggcgggtcct gtaggtcctc caagtgatgt taccaaagcc ataacgagga
     2701 atccaagtgc caagtgagcc acagaaagtc ctgaagcagt gtgtggagcc acctgtgctt
     2761 taatagccaa gtcagaaaaa tcaactgttt gtcctgcttc tattgccttt tgtttcatga
     2821 attgaagcac ttcagcacca aagaagtttt tagtcaaacc aagagctgca aagaacaaaa
     2881 caaatgaacc aacaaactca ttaatcaaac cattgacagt tgctgcatag cgactttctt
     2941 ttgtaccatg gtcaatactt gaaatagttg agaaagttcc caagatgtta tttggttttt
     3001 cagttttcaa gtagaatgga cggtatgttg ccacaactaa ggcttggcca aagatagccc
     3061 ccaagacttg cgcgataatg taaggtacca cttgtgccca agggaaaaga ccgctaactg
     3121 caagccctag agtgaaagca gggttgatgt gattcccaga tacgttacca aacatcaagg
     3181 ctgggatcat aacccccata ccataaccaa cagcgatgac gatccagcca ctttggtgac
     3241 ctttcgtacc tttaagttca acgttggcaa ctgcaccatt cccaagaatg atcaaaatgg
     3301 cagttcccaa aaattcagtg gcatacttca gtgcccatgt gaaatccatt tgctagattc
     3361 tccttaaaat tttttagata ttccttattt tatcaatttt taccctattt agcaactgat
     3421 ttctggaaat atttttaaaa aaataggatt catagtttcc tagttcaacg tacttgtaag
     3481 cgtttttatt cttcacgaaa gacctcattc tcaaaaccag gaaaaagccc acatctgtga
     3541 tcttttcctt gttcctagat tctaaaatct attatttttc atcttctttt ttcttgaaga
     3601 atcctaatcc tagaccagct aacaaggtca tgataccagc actagccaag gtagcattag
     3661 cttctgtacc tgtgtttggc aattcctctc tcttacctgt ctcataagtc ggaacttctg
     3721 ggtctggatt cactggagtt tcagtttttg gagtacctgg ttctggagtt ggtttatctg
     3781 gtgttggagt ctcttgattt ggtagttctg ggtttggtgt cggaacactt ggatgctctg
     3841 gatttggttg tgggattggt ttttctggag tcggttcacc tggagtacct ggttcctgag
     3901 gacttggaat ttctggtttt tctggagttg gtttatctgg tgttgataaa cggtcatacc
     3961 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     4021 tatctggatc tttgtacttg tcaatcttac cagatataac ctcgtcccag tttcctgttg
     4081 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     4141 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     4201 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     4261 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     4321 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     4381 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     4441 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     4501 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     4561 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     4621 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     4681 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     4741 atcatttttc aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc
     4801 taagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     4861 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     4921 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     4981 acggtgactt tgagtgttta ctcctactct ttcattattc tctgaaaata cttgtacggt
     5041 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     5101 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     5161 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     5221 ctcttcagaa ccagatctaa cccaaccatt attaagggca tttgcttttg tatttgtatt
     5281 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     5341 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     5401 ctgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     5461 gtcttcagta gtttatatac tctgtcatca tctttagctt tagaagcagc tgagtttagc
     5521 caagttgggg tattaggagt atctttatca acctgtttca agacattatt caagtcattt
     5581 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     5641 ggcttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     5701 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     5761 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     5821 tacgattttt aaattctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     5881 tcaaaccttt cttatacaag tcttcattct gatacaagtc ttcattctga acgatttcgg
     5941 ctacacggtg aatggtttga ttgtataccg tcttctctta accagcagta tccttagttt
     6001 taatgactac tcgataggtt cctttagaac cgttatagtc atctagtttt aaaaaagcat
     6061 tccaaacatt caaaaatagt tggaacttcc cttaataaat ccgtcacttt ctttttcaag
     6121 atagcccaag cttgctcaat aggattcaaa tccggtgaat aaggtggtag aggtaagaaa
     6181 aagtgtttat cttggatgca gagttcatcc aaaatgttct tgggatgaaa actagcattg
     6241 cccatgacaa taacatgagg tgtcttcaaa gcaggtagga gttgcgtttt gaaccactcc
     6301 acaaagaaat cgcttgtcat gcttttcttg taaatcatgg gagctataaa ctctccgtct
     6361 acttgtcctg caacaattga agttcgctca aaacgacgtc cgctaatctt ttcatagact
     6421 ttctcccctc taggagcccg tgcataagga cgatagaggt agcggtcgat tcctgtttca
     6481 tcaatatata cgattggtaa atcttttagg ttatccaaaa tatcaagaaa ctcagcgact
     6541 ttctctggct cttgttcctt aaagctcgtc atcttttttt aaagtgacct taatatactt
     6601 taaagctgcc catacggagg gcagagcaca atcaaaatgt gccgcaattt cccgtaaaaa
     6661 agcatctgga tgagcctcta caaaggcttt caattcctct aaaggaatct ttcggttttt
     6721 gacgactcgc tttttcctct ctatgtgtcc ttgttcacat ctttcttttc ccacgtgaag
     6781 agagttctga cgccaacacc aaaaaacttg gctgcctcga catggctgtg cccctctttg
     6841 atggaatcta atgctcgctg tttaaaatca gtactatatg ccatagcttt attataatat
     6901 gcttgtttaa aactaagcaa ctatatcaat gttttgttat tagaagactt acttttttta
     6961 ctgaaatcga atttttccta acctcaacat catataaccc caaaattcaa tctgacctgg
     7021 tttgaagaga tgttcgaagc agataaggtt ttactaaaac taaaaaaaat gatataatca
     7081 aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca
     7141 gaaatgggtt gattttgtgg agcttcctga ctaccttcgt caagatttgg aaaatatgga
     7201 cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg
     7261 tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga
     7321 aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtagcaat
     7381 tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc
     7441 taaacacggc atcaaatctt acgtatttga aagccttcgt ccaactccag aactatcatt
     7501 tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc
     7561 tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc
     7621 ggacgctttg actacttata tccgtgcaat cgaaaaccca tttgcagttg aagttgctga
     7681 tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagctg ttgacgtaga
     7741 ataccttaaa gaggttaagg acgtaaacat caacccagcc ttgattgaag aatttggtaa
     7801 agacatgaag attgtctaca caccacttca tggtactggt gaaatgttgg ctcgtcgtgc
     7861 tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc
     7921 agacttctca actgtaacat ctccaaaccc agaaagccaa gcagcctttg cccttgctga
     7981 agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg
     8041 tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat
     8101 cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga
     8161 aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag
     8221 ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca
     8281 agaattcgaa gaaaaacaca accacactta catgatggga tttgaagaaa gcttcggtta
     8341 cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga
     8401 acttgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta
     8461 taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg
     8521 tgctgaacaa atcaaagcga ttatggctaa attccgcaac aatgctccaa cagaatggaa
     8581 cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg
     8641 tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg
     8701 ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt
     8761 tgtaggggaa accaacgaag aatcacaagc taagattgct aacatcgaag cagaaatcaa
     8821 tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta
     8881 tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt
     8941 aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt
     9001 gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc
     9061 ccttactgcc gtaaattttc aggtacattg tcaggtgtcg tagctgaaac caaagctcac
     9121 atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca
     9181 cgctatggaa tcccaactgt accaggtttt gttcatatta cagatggaca aatcaacgtc
     9241 cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgcaggatt gtaaaaaatc
     9301 agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta
     9361 tgcgttttat tgttcctaaa acagttacat cagcatttca ttacagaaca ttttaatttt
     9421 ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattcaa
     9481 ttatccagat tcaatcgcta ttatcgtttt cctagattac aaaaaaacta cgttttgcta
     9541 atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact tctttggttg
     9601 ctacatcttc tccaaaccat ttttgactga tttcttggaa cttgccgtcc ttgtaaagac
     9661 tagaaaaagc ttcatttatc ttcttaacca agtttgtatc ttccttacgg gctccaaccg
     9721 caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg
     9781 cttctaaata ataatttgca tagacacggt caatcaatag accatcaatt cgatcgtttt
     9841 tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa
     9901 tattcttcaa aatttctgga tttgcttcaa agtccgcata accagatgaa ccagcttgag
     9961 ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa
    10021 ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt
    10081 ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt
    10141 tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg
    10201 tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa
    10261 caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat
    10321 ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac
    10381 tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca
    10441 ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca
    10501 tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca
    10561 gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca
    10621 aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggcctct gcgtgtcctc
    10681 ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc
    10741 ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt
    10801 gaaaatcttg gaagacaaat cccagtaggt tgcgcttctg caattcatct agctctaaag
    10861 gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca agcatacgta
    10921 aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa
    10981 tacttagact gaaatcagac aggatttgtt tgtctccaaa gactttattg atatttcgta
    11041 attctaacat agctgccccc tatctataat aactgtactt tttctcaact tttttggaaa
    11101 taattgtcac aatcccaatt aaaatcaagt aaatggctcc tgccaagaac ataggaacca
    11161 gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag
    11221 catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa
    11281 cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttca
    11341 agaccttggc agcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt
    11401 ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga aggcgatcta
    11461 aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg
    11521 ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt
    11581 gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga
    11641 cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca
    11701 tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt
    11761 atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa
    11821 ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca
    11881 tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc
    11941 aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct
    12001 gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga
    12061 gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc
    12121 tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc
    12181 tcagcgtctt cttttgcagt aaggagataa ttttctgcac cactagcatc atgcaattca
    12241 taagaaaatt gtgaagcagc tagcaagagg cgagtttcaa agggattttt ctctaatcct
    12301 tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac
    12361 ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg
    12421 gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca
    12481 tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa tttccctaac
    12541 tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag
    12601 cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc
    12661 aactctgcca aacccaatat caagagagaa tcctctgagt aggtcaaggc ctccaataat
    12721 ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt cagagccaaa
    12781 gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct
    12841 atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg aaaatcctct
    12901 acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt
    12961 gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatgctca
    13021 gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt
    13081 gacttcctca ccctctaatt catatagacc actgactacc ttataccatt cgaaaatggc
    13141 tgaaatgaca accttagcag aggcataaac cggaatacca agtaaaactc cccagatacc
    13201 aaacatagat cctgaagtta acaaaacaaa gagaacatta ataggatgga tgtttaattg
    13261 acttcccaaa atcaatggag agacaaaacg gccttcaata gtttgttcta caataaagac
    13321 aatcactact ttcaaaagca tgactggacc agcaatcaaa cccaatacta gggcaggaag
    13381 catggctaga aagctaccaa gataagggac cagatttaaa ataccagcag taacccccag
    13441 cgtaaccgca tagcgtagac caataatctt gaagaagatg ataaacatta ctgctacaat
    13501 aatagccact gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgatag
    13561 aacttgtcca acaggttcct tcaattttct tggaatgaat tgggtcaaat agttacgcaa
    13621 gcctttccca tcacgcaaga gataaaagag catgaaagga acgataatca aggcaacaat
    13681 cacttgagaa gctccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt
    13741 acttgccaaa actgtagcct ggctagaaaa attggtcaaa acttgctcta attgaggtct
    13801 gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa
    13861 gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac
    13921 tgccaagccc caaatgataa agagagcgat gataacaaag acaatagtga tagctataac
    13981 acgattaacc ttatgcttct ccatccaatc aacaatagga ttcaacaaat aatataacaa
    14041 accagacaaa atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag
    14101 aaaactaatc ttacttaaaa taaaaagatt cagtcccaat aataaggtta ctaaaaatac
    14161 cgtaattgcc ttgttatcta aaaaccactt gaaaaaccaa gataggctaa aatgtttctc
    14221 tttttgctcc ataaatactt cctttctatt gtcctctcat tataccattt ttgaaacaaa
    14281 ataactcttt tttaaagtgc ttacatctaa ttggatatct ttaatttact tgtttttgtg
    14341 atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa
    14401 cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc
    14461 agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc
    14521 agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt gcagcctatc
    14581 aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg
    14641 ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga caagtccttg
    14701 tttataaacg ccaggaagat ggtagtcttc tacttagtga tatggatcaa cacagtggcc
    14761 aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc
    14821 actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag
    14881 aaggaaaatt atctaagctc tatacctatc acagcaagcc aggagcaggc tcacgccata
    14941 tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg
    15001 aagttttaat ctacgatggc gttggcgaat ttgtacgtat gcaggttatt tcaactttac
    15061 cagaagctta cgaaggcttt aatggaaccg ctgctattca tctctctaaa gacggtaaat
    15121 acctctacgc ttctaaccgt ggccatgatt ctatcgcagt atataccatc cttgcggacg
    15181 gtagcttaga gttattagaa atcgttccaa cgcatggtca gactccacgt gattttgatt
    15241 tgacacccaa ccaaaaattt ctcattgttg tccatcaaga ctctgacaat gcaactgtct
    15301 ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc catgttcccg
    15361 aagcagtctg catccgtttt gctccttaaa acaccataaa aaatgaactt ggtattttca
    15421 agttcatttt ttcttatagt ctatttccga cattaatacg gttaatggca cgttgcaaag
    15481 caatcttagc acgacgttct tggtcaatca aatgtttgtc ttgtgcttct tcaattgcac
    15541 gttctgcacg aagtttggca cgttctgcac gactgatatc gatatcacga gcacgttctg
    15601 cagagtcagc gacgattgtg atcatatcat tggcaatttc aataacgcca ccgtttactg
    15661 caatccagtt cacgtgatct ttatcatcga tacgttttac ctttacttca tcaactgcta
    15721 aaaccgcaat catattttca tgtcgtggca agatccccat ctcaccatcc agagttcgaa
    15781 ccgatacata gctggcatgg tgatcataga cgagaccatc tggtgtcacg atctggacag
    15841 ttaactgagc cataggtcac ctcttaaaat cccatttttt cagcttttgc aatcacatct
    15901 tcgatagaac ctacaccacg gaaggcatct tctggcaagt ggtcgtattt accatcaagg
    15961 atttccttaa agccacgtac agtttcagca actggaacat aagaacctgg ctgaccagta
    16021 aattgttccg caacgttgaa gttttgtgac aagaagaact ggatacgacg ggcgcgagca
    16081 accaaggtct tttcttcatc agaaagctca tccataccaa ggatagcaat gatatcttgc
    16141 aattcatggt aacgttgaag gacacgtttt acttcagcag caactgcata gtgctcttct
    16201 ccaacgattt caggtgccaa ggcacgtgag cttgaagcaa gtgggtcaac ggctgggtag
    16261 atacccaatt gtaccaactt acgttccaag tttgttgttg aatccaagtg agcgaaggct
    16321 gttgctggcg ctgggtcagt atagtcatcc gctggcacat agatagcctg gatagaggtt
    16381 acagaaccct tcttggttga tgtgatacgt tcttgcaatt gacccatttc cgtagcaagt
    16441 gttggttggt aaccaacggc tgatggcata cgacccaaaa gggcagatac ttctgaacca
    16501 gcctgagtga aacggaagat attatcgata aagagaagca cgtcttggcc ttccacatca
    16561 cggaagtatt cagcgattgt caaaccagta agggcaacac gcatacgtgc tcctggtggc
    16621 tcattcatct gaccaaagac catggctgtt ttctcgataa cgcctgattc tttcatttcc
    16681 cagtaaaggt cattcccctc acgagtacgt tccccaacac cagtaaatac tgaaatacca
    16741 ccgtgctctt gggcaatgtt gtgaatcaat tcttggatta agacggtttt accaactccg
    16801 gcaccaccga aaagtccaac tttaccacct ttaaggtaag gggcaagaag gtcaataacc
    16861 ttgatccctg tttcaaggat ttcagaagag gtagacaact catcaaaagt tggagctttt
    16921 ttatgaattg gctgacgctc tgcgtcttct gtaaaaggag cttccaaatc aatggtatct
    16981 cccaaaacgt tgaagacacg tcccaaagtt tctttaccta ctggtacaga gattggacga
    17041 cccgtgtcca atacttccat tccacgagtc aacccatctg ttgattccat ggcgatagta
    17101 cgaaccatac catctcctaa ctccaaggct acttcaagga cgatttttgt ttttctttcg
    17161 tcatttttgt agacgacaag tgcattgtta atctcaggaa gtttttcccc tgctgcaaac
    17221 aaaacgtcta caacgggacc gataacctga gcaattttac ctgaactcat ctccttctcc
    17281 tattctatat aagatactgt cggttcctag ctcaactagg tcctaagttc attttcatac
    17341 gagctggact agagcctatt ctaaggcact agcacctgct acgatttctg taatttcttg
    17401 tgtaatcgcc gcctgtctgg cacggttata ctgaattgtc aaatcattga tgactttctt
    17461 agcattatct gtcgctgttt gcatggctgt catacccgca gcattctcag ctgtcttggc
    17521 atcgataatg gcaccgtaaa tcatactttc tgcaaactga ggcaacaact gctccagaat
    17581 ttcttctcgg ctggtttcca attcaaaagt caagctgtac tcttcatccg cttcatttgg
    17641 atccaagtca acaatcggaa gcatttgttc cacacgcatt tgactggtta gcgtattgac
    17701 atggtggttg tagcaaacat aaagctcatc aaagagttca ttttggtaca tttcaacagt
    17761 ttttgaaata atcttacgaa cttgatcaaa gctaggttgg tctgccaagc cacgtaattc
    17821 ataaagtggt tgaataccgc gagccttaaa gaaatcagct cccatcccac cgatacagat
    17881 catttcaaaa cctttaccgt ctgggtggta ttcttctttc aactccataa cagctttcaa
    17941 aatagaggaa ttataacctc caaccaaacc gcggtctgaa gtgataacga tatagcctgt
    18001 cttcttcaca gaacggctaa tcaacatcgg attagttgaa gcaccagctc cattaccatg
    18061 aaggatatct gtcaaaagtt tacgcacttt ctgagcgtaa acttggaagt tgcgagcagc
    18121 ttcttcagaa cgacctagct tagcagccga taccatttgc atggcattag tgatttgact
    18181 cgtatttttt gttgaggcga tttttgtttt aatatcattt agagatactg ccatctgaca
    18241 cctctattct tattggaagc tagattgatt gagaaactct gtaatcgcag catccaagac
    18301 tgcttcttct ggcaagtctt ttgtatcacg aatggtttcc aaaatctctg gatgttgagc
    18361 atcaaagaag gtatggaact cttcctcgaa acgaacaata tcatctactg gaacagtatc
    18421 caagaaacca tgtgtcaaag cataaagaat ggttacttgt ttctcaacag gtaatggttt
    18481 gtgaacaggt tgtttcaaga cctcaacggt acgacgtcca cggttcaact tagcctgtgt
    18541 tgctgcgtcc aagtcagaac caaacttagt aaaggcttcc aactcacggt atgaagcaag
    18601 gtcgatacga agtgtaccag caaccttctt catggctttg atttgtgcag aaccacctac
    18661 acgagataca gatgaacccg catcgatggc tggacgaata cctgcattga agaggccatc
    18721 gccaaggaag atttgtccat cagtgataga aatcacgttg gttgcgatat aggctgagat
    18781 atctcctgct tgtgtctcga taaatggtag ggctgtaatt gatccaccac caagttcatc
    18841 agaaacttta gctgagcgct caagcaaacg gctgtggaga tagaaaacat cccctgggaa
    18901 ggcttcacga cctggaggac gacgaagcaa gagcgatagt tcacgataag ctaccgcttg
    18961 ttttgataga tcatcgtata caatcaaaac atgcttacct tgatacataa attcttccgc
    19021 catagcaacc ccagtataag gagctaggaa gagcaatgga gatggttgtg aagcagaggc
    19081 tgtcacaacg attgtgtagt ccaaggcacc gtactgacga agtgtttcta cttgcgtacg
    19141 aactgttgat tctttttgtc caatcgcgac gtagatacag atcatatctt gatctttttg
    19201 gttcaagatt gtatcaatcg caatggttgt tttccctgtc tgacggtcac cgataatcaa
    19261 ctcacgttga ccacgaccaa tcggtacaag ggcgtcaata gctttcaaac cagtttgcaa
    19321 tggttctgaa acagacttac gttgcataac accaggagct ggtgcttcta ctggacgagt
    19381 tttatcagtg tggatttctc caagaccgtc aactggacga ccaagcggat ccacaacacg
    19441 accaatcaga ctttcaccta cagggacttc catgattttc cctgtacggc ggattgtatc
    19501 gccttcacgg atatctgtaa agtcacctag gatgataata ccaacgtctg ttgactccaa
    19561 gttttgagcc ataccataag agccgttttc aaaattcaac aactctccac tcatgacatt
    19621 ttcaaggcca tgagcacgcg cgataccgtc cccgatatag gttacaacac ctgtttcagt
    19681 cacatcaaaa ttgggtttga aattttcaat ttgttgctta attaaagcgc tgatttcttg
    19741 tgcgttaatt gccaaaagaa caccactttc tatttcaaat tttctttaac aactttaagt
    19801 tgttgtttaa tactcacatc aattgtcttg tgattggcaa aaatgacaaa accaccaatg
    19861 agactttcat cgatttgttc ttttacactc cttactttca gagacatttt tttctcaatc
    19921 aaagggagca aacgagtctt ctgttcatca gttagaggat gagcagacgt aatcgtcact
    19981 tcaaatcgat ttgtttcttt ttcaagtcgg ttcaagcaat ctacaagcac atcataaaaa
    20041 agatttgctc tgtgattgta ggccagaacc tggataaagt tttgtaataa aggcgacaca
    20101 gaatcttgga aaaaagcaat tgttttttcc ttatccgact cgtctactgc cacttgtttt
    20161 aaaaaagaag gcagacctgt tttttcaaca acttgcttga tttgagtcaa gtctgaaaag
    20221 atacggtctt cttctccttt ttcaagtacc aattggacaa aaggcatgct gtatttttca
    20281 attaccttta ctgttttctt gtccattaag cttctcctag ctgatcgata tactgatcaa
    20341 tgagtgcttt atgggcatga ctgtcaaggt tttgtgagat gattttacca gctaagctga
    20401 tggtcaaatc tgcgacctca cccttaacac tctgtaaagc ttctacttta ttttgagcaa
    20461 tttcttgatt ggctttttct tttaagtgtc ctgcttctag tttagcatct gctaagatat
    20521 tagccttact ttgctcagct gtttcctttg cattttcaat gattgtctta gcttctttac
    20581 ggctaccagc caattcatct tcgcgttttt gagccaatac ttctgctttt tgacgggctt
    20641 cttcagctct gtcaatatct gaagcaattt tttcagctct ttcttcgaaa atgcctgtaa
    20701 tattagacca tgcaaatttt ttaatcaaga ctagcaaaag aataaaagag ccagtgatta
    20761 aaataaaatt accaattaat tcacctactg ttacgtgcat cagttactcc tttctattcc
    20821 tcttcaatat taatcttatt ccctaaatac acagatgtca aaagagtaaa aacataagct
    20881 tggatgcagg aaataaagac agaaaatgca gtccaagcca aattagctcc aaaggctact
    20941 ggataccaat aaatagcttg gtgggaaaga agaagtaaca aactcgtcat gacctctcct
    21001 gcaaagatat tcccaaaaat ccgcaaagcc aaagataaga agtttgtaaa ttcttccaag
    21061 atattcatcg gtatgacaaa aacaggactc ataaaagatt ttatactttt tttaaatcca
    21121 cgacgacgaa cgctttctat atgtgtcaac aaaatgacaa gaaaagataa ggttaagtca
    21181 tactgtaaat tagcggttgg cgaactccac cagttagtcc catcgatcgt ttgaagcttt
    21241 gtcattaagc caaggttatt ggcaatcacc atgaaaagga ataaacaaag gaaaaagagt
    21301 gagtaatctt tcatgtagcg cgaaccaatg ttaggttctg taaatccaat aacaaagtca
    21361 tagacatact caagtacatt ttgctttcct ttgggtttca aggtcatatt gcggcttgcc
    21421 caataaataa agacaaaaat aactcccaca atcaacaaag tcatggctaa catagttaga
    21481 ttgaagataa caggaccaat agagatgatt ggattaatac tttcttccat ctaaaatcct
    21541 cccttttctt ctcgttccat gtatttattt gataataaat gagaagacaa gagttacaaa
    21601 gaaagttcct tcaataaagg caacacctaa aaacatcaaa ctacgaaact cagaaagcat
    21661 atctggttgg cgtgctactg atttaaacag tccattcatc aataaacctt caccgacaga
    21721 tacgcccata caggcaatac ataagcctaa aaatgttaaa ttcataacaa attctccttt
    21781 aaaataaaat ttacttactt agtgtagtcc taaaatttaa atttgtcaac ttttaaccgc
    21841 tattggaagc gtttaataaa aattatttcc attt
//
LOCUS       DAVBNN010000032        20759 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBNN010000032 DAVBNN010000000
VERSION     DAVBNN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.032"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..232
                     /locus_tag="VQ847_001286"
     CDS             <1..232
                     /locus_tag="VQ847_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050630.1"
                     /translation="HPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLIKLIKRN
                     AFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
     gene            complement(625..2352)
                     /gene="ezrA"
                     /locus_tag="VQ847_001287"
     CDS             complement(625..2352)
                     /gene="ezrA"
                     /locus_tag="VQ847_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3050631.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2434..4380)
                     /gene="gyrB"
                     /locus_tag="VQ847_001288"
     CDS             complement(2434..4380)
                     /gene="gyrB"
                     /locus_tag="VQ847_001288"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3050632.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4395..4958)
                     /locus_tag="VQ847_001289"
     CDS             complement(4395..4958)
                     /locus_tag="VQ847_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3050633.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5043..5597)
                     /locus_tag="VQ847_001290"
     CDS             complement(5043..5597)
                     /locus_tag="VQ847_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3050634.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5608..6831)
                     /locus_tag="VQ847_001291"
     CDS             complement(5608..6831)
                     /locus_tag="VQ847_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3050635.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6868..9318)
                     /locus_tag="VQ847_001292"
     CDS             complement(6868..9318)
                     /locus_tag="VQ847_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3050636.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9518..10447)
                     /locus_tag="VQ847_001293"
     CDS             complement(9518..10447)
                     /locus_tag="VQ847_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3050637.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10587..10874
                     /locus_tag="VQ847_001294"
     CDS             10587..10874
                     /locus_tag="VQ847_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3050638.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10908..12242)
                     /gene="ciaH"
                     /locus_tag="VQ847_001295"
     CDS             complement(10908..12242)
                     /gene="ciaH"
                     /locus_tag="VQ847_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3050639.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12232..12906)
                     /gene="ciaR"
                     /locus_tag="VQ847_001296"
     CDS             complement(12232..12906)
                     /gene="ciaR"
                     /locus_tag="VQ847_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3050640.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13015..15561)
                     /locus_tag="VQ847_001297"
     CDS             complement(13015..15561)
                     /locus_tag="VQ847_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3050641.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15684..16124)
                     /locus_tag="VQ847_001298"
     CDS             complement(15684..16124)
                     /locus_tag="VQ847_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3050642.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16099..16968)
                     /locus_tag="VQ847_001299"
     CDS             complement(16099..16968)
                     /locus_tag="VQ847_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3050643.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16946..17446)
                     /locus_tag="VQ847_001300"
     CDS             complement(16946..17446)
                     /locus_tag="VQ847_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3050644.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17457..18155)
                     /locus_tag="VQ847_001301"
     CDS             complement(17457..18155)
                     /locus_tag="VQ847_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3050645.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18148..18384)
                     /locus_tag="VQ847_001302"
     CDS             complement(18148..18384)
                     /locus_tag="VQ847_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3050646.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18484..19410)
                     /locus_tag="VQ847_001303"
     CDS             complement(18484..19410)
                     /locus_tag="VQ847_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3050647.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19485..20300)
                     /locus_tag="VQ847_001304"
     CDS             complement(19485..20300)
                     /locus_tag="VQ847_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050648.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20304..20624)
                     /locus_tag="VQ847_001305"
     CDS             complement(20304..20624)
                     /locus_tag="VQ847_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3050649.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6259 a         4550 c         3666 g         6284 t
ORIGIN      
        1 tcatcctatt tttcagactg tctttaaaac cttcctcaaa gataaagaaa agattatcaa
       61 cgcccttcaa ctacactatt ctaatgccaa actggaagcg accaataatc tcatcaaact
      121 tatcaagcgc aatgcctttg gttttcgaaa ctttgaaaac ttcaaaaaac ggatttttat
      181 cgctttgaac atcaaaaaag aaaggacgaa atttgtcctt tctcaagctt agctgacttc
      241 aacccactac agttgacaaa gagcccagat taggaactat ccgtgagttc tctagtctgg
      301 agatttttca atagacttcg ttattgaacg gttaccaagt tactcaaagt acagatttga
      361 agctgcagat aagactgacg aaatcacttt aatactaaat gaaaatcaaa aagcaaacta
      421 agagcctcag gctgtacttg agtacggtaa ggcgacgctg acgtgatttg aagagatttt
      481 cgaagagtat aaaacactgt tttgaggtgg tggataaatc ggctgggcaa aaactcaatc
      541 tcaggagaaa atgaagtaaa tctccccaca actatagaaa aagatttgat tctgctcctc
      601 acacaataaa atctttttct tttattaaaa acgaatcgtt tcacgtgttt tctcatatga
      661 ggtaacaaag cgattggtta caccaggctc tgccacttcc aatgcttgag aaatcttgtc
      721 aaatgaagcg tgataatcaa attctttttc aaaaatatct aaagcttcgt taaatgcttc
      781 ttgaatgcgt tcatcaaatg agcgatagcg gttagaatat tgcaagagtt gctctgtcaa
      841 agttgcatat tgtacaatat tataagtttc cgtttctaaa gcttccatat cattcgttgc
      901 aatttcaaga actcgggtaa cagattcaat gttaatcatt ttttgttcta actcaaccat
      961 taaatcctcg gtattattgc ttgccgtaaa gaataacttc aagaaagttt gtggaatacc
     1021 tggcagattg cgtttttcca tgtatcgctt gatagtatgg agacgattga cataaacatt
     1081 ggccttttga cgtgcattaa tatcatcttt ctcaatttgt gtcaggcgct cactaactga
     1141 aatttgctca tcttcaatat cttttagttg agtttgtaaa tcctcaagat tttcttcaag
     1201 aactgaataa gcttgggttg gttcttcttg atttgaagtt acctcaacaa tagctgcctc
     1261 aaaactctct aattctgtct gaatacgacg aacatggctt gcagctgtct caggaagtaa
     1321 ataggtcttg ttcaaacgtg caatatcttc tcccaataaa gtattattct ctttcatatg
     1381 ttgaaggtaa gttggaagag ttgcaagtag attttccact actttctgag cagcaatttc
     1441 tcgagtaaaa atatcataca aggcattgat ttcctcttgt gcctgtccat tctcatattc
     1501 ggcattatcc aattccaact gacgaatatt ctcttggttt ttcttgaatg cttcataaag
     1561 caagtggaaa cgcgcttcaa tatccgtttc aacaaaatga taattagcat caattagttt
     1621 acgataaccg gcttccaaat cctgtaattg atctggcaat tctgtagaaa gcgtagtaac
     1681 caaggctgga acacgatcca caatatgact taaggccaaa atgtgatttt ctgtattatc
     1741 caaaatcact gcggcttcca cagggtcacc cgatgaattc aaggttacaa attgtgaaaa
     1801 ttcagattgg atattttcta attgtttttc aatttcatcc aaggcttgac catactgttc
     1861 tgaattttca gcaactctat gctgaagttc ctcaaataaa tccaaagcat gaagaacacg
     1921 accactattt ttagattctt gcttctctaa gtctgccaaa gcattgcgaa ttgccgcaat
     1981 atcttcttca atcaaagtaa tttgactctc aatttggtca atttgatgac tggccttgag
     2041 aaaacgaaat gaatggttat agccctctgc ttcaaagaga ttattttcaa tatcggcaaa
     2101 agagttgaga gataaatcga cccatttttg attccattca cggaaagcca cttgactttg
     2161 tccaatcaag tgcatatttt ttacagcttc tacttcatca tttactggaa gattgtatag
     2221 ttcttctttt ctttcttcta gtgcctctaa tctcccctcg tttcgcttac gtagaaagat
     2281 tgccactaca taagccagaa ctaaaatgac tgcaattgca accattaaat aaattagttg
     2341 tccattagac atatcaaact ccttttttac ttgaaacaat cgtaacgatt atatcatatt
     2401 ttttagacca agggaactac ttctccctat tttttagaca tcaagtgtac tatagacagc
     2461 attttcttcg ataaactcac gacgaggctc tactcgatcc cccatcaaca tatcaaagat
     2521 tttatctgct tctgcagcat catctacaga aactctagcc atcaagcgat gttcgggatc
     2581 catggttgtt tcccacagct gatgatcgtc catttcacct agccccttat aacgctgaat
     2641 agtcggtttg gtacgacctt cactataacg ggctaaagct tcttggagtt tgatttcttg
     2701 atctgcaccc ggctggatat attctttaat ctcgcttcca accttgacac catagattgg
     2761 tggttgggca atataaacat aaccagcttc taggattggt ttcatataac gataaatcaa
     2821 ggttaaaaga agggtacgaa tatgggctcc atcgacatcg gcatcggtca tcaaaacgag
     2881 tttttggtaa cgggctttcg aaacatcaaa ttctgcgcca aatcctgttc ccatggctgt
     2941 gaaaagacta cgaatttctt cgttagctag aatcttatcc atacttgctt tttcaacgtt
     3001 caaaatctta ccgcgaattg gaaggatagc ctgaaactca cggttacgac cagatttggc
     3061 tgatccacca gctgagtctc cttcgacgat gaagagttct gtttcagcag ggttattaga
     3121 agaacagtct gctagtttcc ctggaaggtt ggaaatttcc aaaccagatt ttttacgtgt
     3181 gacttcacgc gcacgcttgg cagccacacg agccttggca gccaaaattc ctttttctac
     3241 gatacgtttg gcaatctgtg gattttccat gaggaaatcg gagaaggctt cactgaagag
     3301 gcgattggta atcttgacca cttcgctatt tcccaatttg gtcttggttt gtccttcaaa
     3361 ctgtggattt gggtgtttaa ctgagataac tgcagttaat ccttcgcgaa catcttcccc
     3421 tgttaaatta tcttcattgt ctttcagtaa cttattctta cgagcataat cattgataac
     3481 acgagtcagt gccgtacgga aaccttgttc atgcgttcca ccttcatggg tatgaatatt
     3541 attggcgaaa ctcatgacat tttcatggta acctgttgtg tactgcatgg ctacctcaac
     3601 tgtgatatca tccatctcac cgtctgtata gattggtgta tcaaagatta catccttgtt
     3661 ctcgttgata tattcaacgt aactagcaat cccaccttca taatgataat gcttggtttg
     3721 ttccaaacct tggcgcttat ctgtaattga aatttgaaga ccgcgattta gaaaggccaa
     3781 ctcttgaatc cgtttattta atttatcaaa atcaaagatt gttgtttcag tgaagatttt
     3841 tgggtccggt gtgaagtgaa cagttgttcc tgttttatcc gtatctccaa ctatttcaag
     3901 atctgcgaca acatgaccac gacggtattc ttggtaatga atcttaccat ttttgtgaac
     3961 atgaacgtct aattgagtgg aaagggcatt aactactgac gaccccaccc cgtgaagacc
     4021 acctgaaacc ttgtatccac caccgccgaa ctttcctcca gcgtgaagga ctgtaaagac
     4081 ggtctcaaca gcaggacggc ctgttttttc ctgaatatcg actgggatac cacgcccatc
     4141 atccacaaca gtaatcgaat catctggctc aataaaaact tgaatatggc tggcaaatcc
     4201 tgccaaggcc tcgtcaattg agttatcaac aatttcccag actagatggt gaagaccttc
     4261 ttttgaggtt gatccaatgt acatccctgg acgcatacga acagcctcta agccctctaa
     4321 aacttgaatt tgactggcat cataatcctg tgcctgcaga tttttgattt cttctgtcat
     4381 cttattcctt tttcttatat gtctaatact tgtcttaaat tcacgatact ggtaaacaag
     4441 tgggtatcaa gtcctgcagc ttgacctgct tcgatatcaa tcggccgatc accaatgaca
     4501 agaccagagc taatctgata cttttctctt aaataaagca tggattcggg atttggcttt
     4561 ctcttaaagc ctgagctaga agtcaccact tctgtaaaat aagctgctat agaggttttt
     4621 tctaaaattt ccaaaacctg atcatttcga tgagagacca aaaaatgacg gccaccttga
     4681 tttgaaatga cttccaatag gtcagaaact ccttcaaata aaatcgggtg ttcaagctct
     4741 ctggcttcat tttccttgta cttttctaaa aaattctcta aattgggagc gaatgtctca
     4801 atcgcaaaag gagtagaaac ctttaaagct tgatagacac tgtcatggtc ttgtgtgata
     4861 ccatacagtg ccaatgtttc aacaaatgca gctgttgaag tttcataatt atccagtaaa
     4921 gttccaccta aatcccagat gtaatcgtga tatttcatat ccttcattat agcatttttt
     4981 tatgaaaaaa gcgatgattt ccctgagttt tccacataaa aaacgagaga ataactcccg
     5041 ttttactgat ttttaccaaa gacatcttga tagagcattc ctgttcgtaa actctctgcg
     5101 tcccctccta gttgctccac caactcgtag gcaaaggcaa gggctgttga aggaccccga
     5161 ctggttgtca actgaccatc taccactact gtttccttga cgtagtgacc atcaaggatt
     5221 tgctcttgaa cgccgtcata acaagtgtat cgcttatttt tcaatatctc tgcttgattg
     5281 agggcaattg gtgccgcaca aatggctgct agtttcttcc cttcttgctc gaagctttgc
     5341 aattcttgaa tcaaggtctg attatcacgt aaatgtgcag aaccaggcat acctccagga
     5401 agaacaatca tatcatagtc tgataaatct ccatcaaaga catgatctgc tcttacttgg
     5461 attgcatgcg aacccgttac ttgctcttca aaaccaacca tatcacatgt gatattggct
     5521 cgacgcaaga catctacaac tgtcaaggct tcaatttctt caaagccctg agctaacata
     5581 actgctactt ttaccatgat tttctcctta tttaatttgt tttaatacaa cctttttccg
     5641 tttgaatggg acttttccgc tcttttcttc agctagatta gtctggtagc tcatcgataa
     5701 aagcaaacca acaccaatca gattactgat aatagctgat cccccttgcg aaataaaagg
     5761 caagggaatc cccgtcaaag gaagtagtcc agtcacagca ccgatattct caaagatgtg
     5821 gaagagcaac atcataatca aacctgtgga aatataagtg tagaactggt tatttgattt
     5881 aagagtaatc ttcaacatac ggtaaatcaa catgagatag agggcaataa ccaggacaga
     5941 gccaataaag ccaaaatctt ctgcaataac cgtaaaaatc atatctgact ctcgaactgg
     6001 gataagcaga ttcgaagcat taaatccctg accaaataag ccaccactcc caatggcaat
     6061 ctgtccttga gcctgctggt aagtcgttgt ttgggcaaac tcaaagggat tgagccaagc
     6121 caaaatccga ttaatttggt aggtcggcat tccaatctgg tgaagaaaag ctcgtccgtc
     6181 cttgctaata aagatagcta agaaaccagc aactcctgtt acagcagtca caaatactgg
     6241 gataataatt ttccaagaaa cccctgataa taaaacgatt cctgagaaaa tggctacaaa
     6301 aaccaaagcc gtccccaagt cactttgaag tgctaaaaga actaggactg gaatggtaaa
     6361 gagaatcatc cagaaaatta acaaaaagtc cagcggaacc gtgcgtctcc attccttatg
     6421 tttctttgta aattggacaa tgacacgagc caacatgagg atataggata tcttcataaa
     6481 ttctgacggt tggaataggg taattccatt tattgatacc cagtttttgg cacccgttga
     6541 tgcaactaag cttggattat aaaatacaat cggcaagatc ataagtccca agcctaaaat
     6601 atatagaaag ggggtcacct tccaaagaaa ttctgtatta aagagcatga ccacaaaacc
     6661 aatcacaagc cccaaggcaa tccaggcgac ctgctgccct aaaatgggca gaatattatt
     6721 gggataatca tgactaacgg ctatatagat agccaccaca ccgatgacca gtagaaaaaa
     6781 tactggcaag agcaaactgt aatcgactct tgagtcgaga gaacgtttca tatatactaa
     6841 ccttatactt tcatacaata ctatttatca aagttcatta aaaaatctat caatagcctc
     6901 gtcaacttcg gatcgagaga tggttttaac agtcgcttct tctgctagag atgctactat
     6961 ttgtttgccg tatcgttttc cgacgattct cctatccaaa ataagagtta aggaacgttg
     7021 gtattcacgt ctcatacttc ttcccaaagc ctgttttaaa cgaataatgg ccattggcaa
     7081 ttgataatca taaaaggcat ttttcccttc ttgattcagt tcttgattaa tctttttcgt
     7141 caagggttct tgaggatttt ggaaaggaag cctcggtaca acttgaatca caaaaggatg
     7201 gcttgaaaaa tcaactccct cccagaaact tgctgcacca agcaagattt gttgttcacc
     7261 tttttcaaag cgtttcttta gctgatgaac atccccattt ttatactggg ccaagtggct
     7321 aactgtaagt aaatccgata ctgctagaag catgtcttta gcggtaaaga gaaccaaaat
     7381 cggttgctgg aaagcttgaa tttccactag taaagcagct acctctctgg catagacttc
     7441 taaggaggtt tctgttacca gagggaaatc tttgaccata accacttctt gttcctgttt
     7501 tccccgagat tcaatcttga caaatttgac ttcaggatag cctaaaaggt ctgccaaaga
     7561 aaccctctga ctaatctcaa gagtagctga tactcccaag acttggcaac tctcaggaag
     7621 taaagaggac agaagagtac ggcctgattt tgtagaagaa atctgaattt tcttttgact
     7681 cgtttcagtt acttcaagcc agtaatcacc ttcagctgta aaatagcgaa ccagctcatc
     7741 aaagccttct acttctaatt ctgaaaaata ctgatggaga ttgtccagag aatctaagat
     7801 atttttccta gatttaccag actgaaattg ttctatcaag tagagacact caaagcgaat
     7861 actttctagt atccgttgtt gaaccctgtt ttcttctcct actaaagcct tatcaattaa
     7921 atcgataata gattgtatat cgtaggtctc ttgaagcaga ttttctagag ctaacaaaat
     7981 cttttggact tcatcaataa tcagtaaacg gtcactgaca aattcaggat tatcttcaag
     8041 tctggttacg agataggcat gattagtcac taaaagcttg caagtctctg ccctttcttg
     8101 actacgtttc caaaaatctt ccgtcacaaa taagttctgg gatgataaat tcccatcatg
     8161 acgaaggtct gctagaaaat gttggtaacg gtagagttgc ccgatttcat ccaaatctcc
     8221 tgtctctgtc tcagtaagcc agaccaagac ttgcatttta aagcgtctaa ataagcgatt
     8281 ttcatcattt tcctgcaagg aatgataaaa ggcatccaac ttcagataat tttgtggtcc
     8341 ctttaagcta tgaatatctg tatggaacac ttccttgagg cgtttacctt cttcttccat
     8401 gatttgattt tgaagaatct ttgtcggaac actaagaaca atttgtcgct ctttggattg
     8461 agataaagcg ggtaagagat agccataggt tttcccaatc cctgtcggcg cttgaatcag
     8521 agagacaggt tcatctttca atagcaagcc aacctcttta gcaaaacttt cttgttcctc
     8581 cctcacttca aggttcaaca gagaaatatt tttagaaaag tcttgagata gttttcgtgg
     8641 ctccagagaa gctgccattt tcttaaaata cagaccttga acttggacca agtctggaga
     8701 actcaggata gattggttgc gataagtttc ctcaataacc aggtaggact catataggag
     8761 agcgtcagcc atttccagca agcgttccaa gagaccttta ggaagctggg tcatcttttc
     8821 ccgtaaaaaa agaagtaatt ctgctgtagc ttgggcatct gaaagggctg tgtgtgcgtg
     8881 tttaagagga attcctaatt ctcgacacaa aatcggcaag ctatattttt ccagttcagg
     8941 gaaaaagacc tgggccaatt cgaccgtatc aacacgaggg tttcttagct catagccttc
     9001 aaaaaataaa ttttccgcca agagattagc atcaaactga acattatggg ctacaaaaat
     9061 cccatcctcc accaagtcaa atatttttct ggcaacttgc gaaaaatcag gtgcttgcgc
     9121 cagacgttgg tctgtcaatc ctgtcagttc tttgatatga gcatccaagg gttcatgtgg
     9181 attgacatcc gtcgtatagt gatcgacgat ttctccatcc tcaatcacga caattcccac
     9241 ttggataatt ttagccttac tacctgtgct agttgcctct aaatccacca caacatagcg
     9301 attaccaatc gttttcatta taaaaaatta taccaaaaaa agggccattt ggcacctaca
     9361 aacataggat aattttcaaa ctcaagaaca ctacttttct taaaaatccc atcgaataga
     9421 gcattctagc ctgctgattt ttgtaaaata gtgaagaaat acgaaaaatt gagagaagaa
     9481 atgtttgcat cttccttctc tcaacgaatc atgtatttta tttaaccatg tcaggatcgt
     9541 agtcataaaa tcctgtatca aggaaacggt ttttagggtg aagtttacga acttcttcat
     9601 ccagcaagaa ggcttgatca tggctaaagt tgccctcttg aatcaagtta cgcgcttgga
     9661 taaagagttt tgcaatctca acaaagttct gaccaggagt gtagagccct tctagtttcc
     9721 agcgagtaaa gccatgctcc accaattctg ttaatttgat catcaaatca aggtcattgt
     9781 tggcaaagat atgggtccca tgattatctt caaaaatgga atagtggctc tctggatcac
     9841 ttggctcagc caagaagagg tcacgtttat gcgtcttttc atcatcgata tgtgtaaagt
     9901 tatagtagtt ttgcaagagt ggacgtttag aatgatggat gacgctagca ccgtaaacca
     9961 aaacttcagc aggaatttcc aaaatctctg gcattttgaa aagttcagct gatggaattt
    10021 cacgcgccaa aacagcctca gatgcgccag ccttttgtcc ccagaagtta atctgacgac
    10081 tgctagttac catggttgaa gcatcgtaga tggtcttaaa tgaataacca tcgcggttaa
    10141 ctacgtaaaa gacgcctgca tccccaatcg taatatagtc tgtcttgatt tcttccaaga
    10201 agtctaagaa aggcttgata cggtccatca tatcttggtg catgagagca ttgaccgcaa
    10261 cgatcaattc cttaccagca tcatgaacca acttagcgat ttcacgtaat tggtcataac
    10321 taaaggtcgt tggcagacga aggccaaaat ctttctcacc gacatagata cggtctacgc
    10381 cagcttcgag tagttgttca acttgttcaa tactttcagc agttgctgta atgacaatct
    10441 tttccataag aaaaattata ccacatttct ccaaaatcat ccatgctttg aaaatgaaaa
    10501 gggactttat tctttttgta acctttctgt aataattctc tgccgaaaaa atgataaaat
    10561 aggtatgtac tgttaaggag agaattatgc ccgtaagaaa attacaatcc tatgaggtag
    10621 actatcaaga agaattaaac cagcagcttc ctcattacca agcttataca cctgaagcgc
    10681 aatctgatgc caatctcaag gaaatcctat tttttattaa tatcgctgtt ttttgtatct
    10741 gtattgctat ctttagtttt atctttttag cattaaaatt atcaactgct cttgcctttg
    10801 ccgcagcaat cggattcagc ttacttgttt taaaagttca acggtctatt atcaaacgaa
    10861 aacgtagaag ataaatccaa aatatcgccc cagttggagc gatattttta ttttttcttt
    10921 ttagatggtg tctgaatggc aatcttcact tcaaagattg ttcccttggg tttattatct
    10981 ttgacagtaa cagttccttt tagagcatct acaatttgct tggctaggga taatcctaaa
    11041 ccaaaaccac ctttttgccg ggttctagcc ttgtctactc gataaaaacg gtcaaaaatt
    11101 ttctttttat cttctgtcga aataccgatt ccattatcag aaacaagtaa ataaagattg
    11161 cgatcggtcg ccgagataag aaaatcaatt tcaccatcct cctcagtata cttgacggca
    11221 ttatcgaaaa gaatggtcat cagttgtttc agaagaagct gatctgtgac aattgttcga
    11281 tggatacgat tttcaaaacg gaagacacga ttattttccg aagcaatcat ctcatagttt
    11341 gtgaaagttg tattaaaaaa gctagttgga acttctgcaa gctctggctt aatcccatca
    11401 tctctccgag ctaagttcag caagcttgtc gttaaaaaac gcatatttcg gacttcttcc
    11461 aaactcgatg caatgctttc actcacatcc ataatggtag cttctggctt acgaaaaagg
    11521 gtctctaagc gattttgcaa aactgcgagt ggagttcgta actcatgact ggcattttcc
    11581 acaaaagact gttgcttctg catactctca agcaggggcc taacactgac cctagctaga
    11641 tagagactgg caagtaaaga caaaatccag aaactagcca tcacgaccac aatcaattgc
    11701 tcatgctttt gactagcctg ctccaactga ctggtattaa tcaagacagc agcatacttg
    11761 atattggttg aaaccgaact aatattggtc tccatcaaaa tcacacgata gatttcttcc
    11821 tgcccatagc tattaaaaac ctgaatctgg tagatatgtc ctagttcttt cttttctaac
    11881 ttaatcttat ccaagcccaa aaatcgattt ccagaaagaa gttgagtaaa gtccttatca
    11941 aagagaatga cttccgtatt ggaactgaca ttaggtttta tttctacttt actagcgtcc
    12001 gccctagcat tttctaaatc tttaatctct tctgttgccc tatttatagc cagctgaata
    12061 actgcttgag gattttcact cagtccatga agcttatcgt ccaccgaagt ataaagactc
    12121 gaatgcatga cttgtaaaat aatcagagtc attgtagaaa aaatcagggt gaagacaccg
    12181 aagttgcgga taaaataact aaagtcatcc gcataccatg tttttttaag tttactgaac
    12241 atcttttaaa agatacccaa cactacgcaa ggtttgcaaa ttctctgcaa aagtggttcc
    12301 ctttaatttc ttacggactt ttgaaacata gacttcgaca accgaaatcg ttgtatcact
    12361 atcaaatccc catagacggt caaaaatctg cgtcttaggc aaaatcacat tttgattttg
    12421 aaggaaataa actagtaaat cgaactcttt ccccagcaat tcgacaggag tatcttcaac
    12481 tttaacggta ttggttgata aattaaccac gatattccca taagtcaagg tgttttcatt
    12541 aaacttccct gaacgtttga gaagggcctg aatccgcatt ttaagttctt ctaggtagaa
    12601 aggtttggtc agataatcat ccgctcccag ttcaaatcca tgtcccttgt catccaaact
    12661 ttccttggca gtcataatca gaactggtgt cgtaattccc ttttcacgca attcttttaa
    12721 gacttggaaa ccattttttt ctggcaacat caaatccagc aaaatcaagt catagacacc
    12781 actctcagct tcgtagagac cttcttctcc atcaaatacc tgcataacat ccgcaaaatc
    12841 gtctaaaaag tcaaatactg aatttgacag acctaggtca tcctcaacca ataagatttt
    12901 tatcatgaga aactcctcct tattaaaact attataccaa atttgcctta aaaaaaactc
    12961 aactctctgc attttacatg agatagctga gttttctttt tattttaggc ttatttatgc
    13021 atttccgtat tgaagaacaa ctgcttcgac tgcagctttt tcacggctaa tcaagtcaac
    13081 acgtgctgca atttccttga ttcccatacc gatgttacgg ctaagagcaa ggtcagaaag
    13141 ttgcggctca aagaactcct tgtattccgc caagcgttgc tgagtcttaa atacatgagc
    13201 aggaaggata acaaagctat caaagctcat atctcctcca agggctgcct taatccaagc
    13261 ccagttttca cgcgcccaag accaagctgt tttctgagtt gcttgatgag ctaggaattg
    13321 gtaataccaa gcagacaagt cctgtggttt gaccacaaat ttgtccttcc aagaagtaat
    13381 caagttttgg atattatccg catctgtact gtatgcaaga gctgctgcca actggcgttt
    13441 aaagacagca tctgttgcgt gagtataagt atcaagataa agtgctaaca agtctttagt
    13501 ctcatgatgt ttcatctcat taatcagaac ttgtgaacga atagctgctg ggagtcctgc
    13561 aagattctcc ttgtgtgttg cgaagatttg gctagcgact tgactagctt ctgcatcatt
    13621 tgagcgaatc atcatcgaaa cagccagctg acgaaccaat tcatcctcat ctgattctcc
    13681 gtctttagct tcaaaaccaa gacggtcata gttatgacga gccaatttag caaccagtcc
    13741 tttgaaggct gtttcagcat ccgttccttc atcaataaag cgctcaagag ctgaaatcac
    13801 ttgagaaaca gctgaaacca ccagataaga ctcttcctta gcaagtttat caagaactgg
    13861 aagcaagtct gcataagaaa tgtgccctgc ctcagccaac aaacgacgtt cttgaacaat
    13921 ttgcagtttg cttgtgttat caagtgtctc tagctcagca agaacagctt ctaacaagtc
    13981 tccttgatag tcggtaatat agtgggcagt attttcagtg ttgagacgaa gagctccttc
    14041 attttcagca agaagagctg cgtagccagg gatttcgata ctttcagttt cgagtgtatc
    14101 aggcaagcct ttccagttgc tattgagggg caccacccag agacggttct tgtcttcgtt
    14161 ctcaccgatg aagaattgtt tttgtgaaat cttcaagaca tcattttcaa ctttgacagt
    14221 aagaactggg taaccaggct gttccaacca agaatccatg aaggctgcga catcacgtcc
    14281 tgacgcttga ccaagggcat cccaaaggtc actaccaatg gtgttgctgt attggtgttt
    14341 ttcaaagtag gcgtgcaaac ctttagcaaa atcagcatct cctagccaac ggcgaagcat
    14401 gtgcatgaga cggcttcctt tggcatagac gatagcgccg tcaaagagtg tattgatttc
    14461 atctggatgt ttaacttcga cgtggacaga ctgaacgcca tcagtagcgt cacgttcaag
    14521 agcaagaggt actccacctg tttggaaatc ttcaaagata ttccagcttg gttcgatggt
    14581 atccacacag acgtattcca tcatattagc gaaactttca ttgagccaaa ggtcatccca
    14641 ccatttcata gtcacgaggt tcccaaacca ttggtgagcc aattcatgag ccacaacaag
    14701 ggcaacttgt tgacggctag caaatgtaga gttttcatcg acaaccaagt aaacttcacg
    14761 gtaggtcaca agaccccagt tttccatagc accagctgag aagtcaggaa gggcgatgtg
    14821 gagagattga ggaattgggt acttaactcc atagtaatct tcgtaaaact cgatagagcg
    14881 aacagcgata tccagtgaga aatcaagatt tgaaagtgga tgtgctttgg ttgagtagac
    14941 acctaccagg gtaccatttt tagttttagc ggtcacccct tgcaaatcac cagcaacaaa
    15001 ggccaacaag taagaagaca tgcgaggtgt tgtctcaaac ttccagatac ctgtttcctt
    15061 acggttttca acatcgattt ctggcatgtt tgacaaggcc aattcacctt ctgcttggtc
    15121 aaagcgaaga gagaggtcaa aagttgcttt ggcttcaggc tcatccacac atgggaaagc
    15181 ttcgcgcgca aaatggctct cgaactgagt agacaagacc tccttcttga ctccatcaac
    15241 tgtataataa gaagggtaaa tccctgtcat gttgtctgta attttaccag aaaaggcaag
    15301 aaccaattca acttgaccag cctcagccaa ttcgatatga agggcttcat tgtcatggtc
    15361 aactgtaaat ggacgagctt gacctgcaac ttctacagag gtgatttcca agtctttttg
    15421 gtggagggag atgcggtcac tctgtgcttg accagtgatg gtcactttcc cagaaaaagt
    15481 cttggtctca cgactcaaat ctaaaaataa atcataatgt tcaggaacaa attgcttaat
    15541 aaaatgttca actgcttgca tagttttctc ctattctaag tttaagagct gctgctcttc
    15601 ttcaaacaaa cttattatat catattttgc ttgagaaaaa aggattggac agcgatttcc
    15661 aaaactttct tccttctaat agtctacagt gggtagacct tgcgaaattc ttctaaaaca
    15721 accttgcttt caggtgtaaa agtcagccct acttcaccca aacagtctgt gaaaaagtcc
    15781 tcatgaacct ggcgccaata ggcaagtgat ttgtctccct caccttcctt aaaggcatgt
    15841 tgcgcagaaa cttgattgaa gagttcaaca gaaacctttg taatttcgac aatgcagaca
    15901 gcctgatttt gactatctaa aatgacatcg aaggtcccta cttggggaag tggttcgtct
    15961 tctagtacat agaggtcata ggctgatgct gttgctgtct tttctccttt aaacaccaaa
    16021 tccgctaaaa ggtctggttc aactccaaaa gcccaagcat cgatttcatc tccgatcaaa
    16081 ggattgattt gcttgtattt attccacatt tcttgcggtg tcatgggtac tcctttgtaa
    16141 ttttttactt tcttctttta tgtgtttaag atgatctgga tggtcaatct ctaaatcaaa
    16201 aatctctgga atagaactgt agtggataat gcacttgata cccaactgat tcattttttg
    16261 tatgaaagaa gtattcagat agcctgctac agcaaaatta atcttgttct ttcttgcttt
    16321 atcctgcata tctcttagca tatctaacat tattggactt tccatatcat gccattgact
    16381 gtttctcata gtcgcaaaaa caaaggaagt caaatcattc attccaacta caatctttga
    16441 aatgcccgtt tccagtatac tagataagtc aaaatacgct gacggtaatt caatcatcgt
    16501 tccgactttc ccagtaaagc catactgacg caatactgta atagcttgtt ttaattggtc
    16561 ggcatcattg acaaaaggaa agataacaga tagattgggg ttggtttgat aaacttctgt
    16621 aacgacatgt gcttcagcct gaaattcatc caaacacgcc agtaaacgcc tagttcctct
    16681 atagccaaac aagggatgcc cttcgtcaaa aaactcttta gtccccacta aacaattggc
    16741 ttctgtattc gttaattcag taaaacgata ccaaacttct tcatctgagt acagggagca
    16801 gatagtctct agataatctt ttacaaattg ctgacaactt gctaatatga tgttttgatt
    16861 aagctctctc aacaaatatt ccccacgaat catgccgacg tggtgaaata gttgaggata
    16921 aattttttca agaatttttt cgccactaag ggcaagttga tttctcatca ttcaccttcc
    16981 aattcatgta agaagtcttg tccagttctg gaaatcctaa taattcagac ttaaccttaa
    17041 agactaatgg cgatgcattt tcttctgtaa tctcttgaat atccatccaa atatatccaa
    17101 gtgaatcatt cgcaccatca gacacagctt ccgaaatcgt aacttgaggt gcactctcat
    17161 tcatttcaac atcatacaag gccatgacat ggtgaaccat aaaatttttt aactcttctc
    17221 tgacgaaaac atcgtagatt cgaggattag agtagcttct aacagtaaat cccgtctctt
    17281 ccataacttc tctagtcagc gtttccgtca gtccttcacc aagttgctga ctgcctccag
    17341 gtagatcata ccgatgttga taagggcctc tcgttttttc aatgcagagt aacttcccat
    17401 tttctaagca aacagcgtag actccaaagt gttttttgat ttccatccaa ctcctcctac
    17461 ttcaaagacc agccaccatc tattgtcaag atttgtcctt gcatggcgct cgcttttcca
    17521 cttgctaaaa aaagactaag ctctgctatt tcctctggct caatccagcg cttgattggg
    17581 gtttcactag ccacccagtc agccaaacca cctggttcaa aatccgcagc ggtcatagct
    17641 gtcttgactg ctcctggagc gataccaaag acctgaatcc cagcttcagc atagtctaga
    17701 gccaactgct tggtgaagcc agccaaggca tgcttggatg aagtataggc gtgaccacct
    17761 ccacctgcta ggctagaagc aatggaacac atattgatga tgattccctt tttattttcc
    17821 agcatttgtg tcaaataata ccgagtcaac tctactggaa taatgtagtt gatttcaaaa
    17881 atctcttgaa tgtcctgcgc cgtttgttcc aacagtggtt tgtaatcatc caaaactccg
    17941 gcagtattac acaaaacatc cacctgaggg caccagtcaa aaataggttc caagtccaag
    18001 gtcaaatctc tctgtaaaaa gtgaaaatca ccctctaaga gtggcttttc accttggtca
    18061 actccataaa cttgatagcc cttctctaaa aagaggcgag cttgagccaa tccgatccct
    18121 gaactcactc ctgtaatgag tacacgttta gtcatgcact tctacccaat ccgttgccaa
    18181 aacatcacaa gctgtcgggc tccacatgga aaaaccttct ccttctccag acacgttgat
    18241 taagaaataa ggtgtcactt caagtgcaag cccattttgc tcgatggtat caaagagttg
    18301 gacatagttt tcagcacctc cccaaccagt tcgtacatat tttttcttag cctttaagcc
    18361 aggtagaatt tcttcaaatg tcatgttttt ctcctttaat gtcaataatt ctccccttca
    18421 ttataacaaa aaaaccgctt taaaacggct ttttgactgt gatttattta catcttcttc
    18481 tacttacggc aaattattcc ctgcagcaag ataaatttca taccattctt ttcttgttaa
    18541 gctaaagttt gccgcttggc taacttctct caagtgctta ggatttgtgg tacctacaac
    18601 tgcctgcatt tttgctggat aacgcaatat ccaagaaatg gcaatagttg aagaggttac
    18661 tccatattta atagctaaac gatcaagtac ttgatttaaa gcttgaaatt tctcatttcc
    18721 aacaaaattc cctttaaaat acccgaattg taagacagac catgcttgaa tgaccacatc
    18781 gtgtaattgg caatattcaa aaatgctgcc atctcgcata gctgcttgac tatcttccat
    18841 attaacatga aaagctgatt caaatcctgg agtaaaagcc gcactcaatt gtagctgatt
    18901 aacagctaac ggctgcttga catctttttt aagcaactcc atcatcatag gattttgatt
    18961 agaaactcca aaatctcgaa ctttaccttg tttataaagg agatcaaagg cttctgctac
    19021 ttggtcagat tccatcaaag catctggtcg atgaaggagc aagctatcta gatgatcaat
    19081 cttcaatctt tgcaaaatac cgtctactga ttttataata tagtccttag aaaaatcaaa
    19141 ataggtaaat tcttcaatgc gaatgccaca tttggactga atccacatct tttctcttaa
    19201 atctggacga ttttttagga caagacctaa cagttcttca caacgaccac gaccataaat
    19261 atcagccaag tcgaaggcat tgattccaac agaaagtgct gtttctacaa gctcttcaac
    19321 ttcttttaca gacttatctt ttattctcat cattccgaga acaatttctg ataattcttt
    19381 gtcatcttga ccaagagtta tgtatctcat caaatttttc tcctttaatt tctaacattc
    19441 ttcccttcat tataacaaaa aaccgctttg caacggcttt ttgactatac ttcactccat
    19501 tttatcttct taaacccacg gaacaagaca aagattccaa taaagaggac agctaaagga
    19561 ataacttttg taaggaaaac atttgaaatt cccatccact cataataacg gagcagagaa
    19621 cccaccacaa gatgggcaat aatcatactg acaaatggac gaaagaccgc ttctttccaa
    19681 ttccaaatac agataactag cgaaatcgta aagacagaca aactatccca gggagccgga
    19741 atataaaagg ctccttcttg tatgaagctt gccattccta catatcctaa aacaactaaa
    19801 agaactatag tcccaacaac aatgtaagtg ccaattttca ttttaggaga atcttggact
    19861 aaacttcttc gtaaaattgt ggccacaagt ccaaatccaa tcagaaaaat aagaagttgc
    19921 cctaaaaatg tgagcaaatt gactgttaag agaggacctt tagaaaaatc acttagtagt
    19981 tgataataac gtaataccgc caggacaaga attggcgtca aaagggactc tttgatagaa
    20041 ctgcgaggtg ctcccttgag aatctctttc attatttttt taggattctt acctagataa
    20101 tcctctgcac tcatgccatc tcgttctgct tctgagaaat ctagcatcat caaatagatc
    20161 tgctctctga gatagtcttc atcatagaga aatccagcaa gattaaaact ttcccacaac
    20221 tcctcaaaat acttttgatt ctcctcagaa aactcatgta gcaaagcgct tgtttcttcg
    20281 taatacttca ttttcttcat ggtttaaccc ccattcttaa tcccttctac tttttgactc
    20341 aaatcgtccc attgttgcca aaagactgag acacgctctt ctccttcttt cattaatgaa
    20401 aaatacttcc gatctggacc atctggcgac gggcgcatgt cgcctcttat ccattgattt
    20461 ttttctaact tttgcaacaa aggataaata gttcctggaa cgatagtatc aaatccagcc
    20521 tctcgcaaag tctgaaccaa ctcataacca taccgctctt tttgaccaat catatccaag
    20581 acacaacctt caagaacacc ttttaatagc tgagtttctt tcatcacttc tcccttctaa
    20641 tctattttgt aatacctact agtaacttca cctatagtat atcacttcta cactagtttg
    20701 taaagcataa tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgcccta
//
LOCUS       DAVBNN010000033        20672 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBNN010000033 DAVBNN010000000
VERSION     DAVBNN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.033"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(4..1683)
                     /locus_tag="VQ847_001306"
     CDS             complement(4..1683)
                     /locus_tag="VQ847_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3050650.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1685..1918)
                     /locus_tag="VQ847_001307"
     CDS             complement(1685..1918)
                     /locus_tag="VQ847_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3050651.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2724..2876)
                     /gene="cibB"
                     /locus_tag="VQ847_001308"
     CDS             complement(2724..2876)
                     /gene="cibB"
                     /locus_tag="VQ847_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3050652.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2878..3063)
                     /gene="cibA"
                     /locus_tag="VQ847_001309"
     CDS             complement(2878..3063)
                     /gene="cibA"
                     /locus_tag="VQ847_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3050653.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3241..3924
                     /gene="tsaB"
                     /locus_tag="VQ847_001310"
     CDS             3241..3924
                     /gene="tsaB"
                     /locus_tag="VQ847_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3050654.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVAPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3921..4358
                     /gene="rimI"
                     /locus_tag="VQ847_001311"
     CDS             3921..4358
                     /gene="rimI"
                     /locus_tag="VQ847_001311"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3050655.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4348..5358
                     /gene="tsaD"
                     /locus_tag="VQ847_001312"
     CDS             4348..5358
                     /gene="tsaD"
                     /locus_tag="VQ847_001312"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3050656.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5398..6704)
                     /locus_tag="VQ847_001313"
                     /pseudo
     CDS             complement(5398..6704)
                     /locus_tag="VQ847_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7038..7332)
                     /locus_tag="VQ847_001314"
                     /pseudo
     CDS             complement(7038..7332)
                     /locus_tag="VQ847_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7439..7732)
                     /locus_tag="VQ847_001315"
                     /pseudo
     CDS             complement(7439..7732)
                     /locus_tag="VQ847_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            7975..9179
                     /locus_tag="VQ847_001316"
                     /pseudo
     CDS             7975..9179
                     /locus_tag="VQ847_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9172..10048
                     /locus_tag="VQ847_001317"
                     /pseudo
     CDS             9172..10048
                     /locus_tag="VQ847_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10135..11751
                     /locus_tag="VQ847_001318"
     CDS             10135..11751
                     /locus_tag="VQ847_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050657.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11771..12614
                     /locus_tag="VQ847_001319"
                     /pseudo
     CDS             11771..12614
                     /locus_tag="VQ847_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12682..14183
                     /locus_tag="VQ847_001320"
                     /pseudo
     CDS             12682..14183
                     /locus_tag="VQ847_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14195..14944
                     /locus_tag="VQ847_001321"
     CDS             14195..14944
                     /locus_tag="VQ847_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3050658.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            14957..16129
                     /locus_tag="VQ847_001322"
     CDS             14957..16129
                     /locus_tag="VQ847_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3050659.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16524..17387
                     /locus_tag="VQ847_001323"
     CDS             16524..17387
                     /locus_tag="VQ847_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3050660.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17673..17906
                     /locus_tag="VQ847_001324"
     CDS             17673..17906
                     /locus_tag="VQ847_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050661.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            17928..18605
                     /locus_tag="VQ847_001325"
     CDS             17928..18605
                     /locus_tag="VQ847_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3050662.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18617..19282
                     /locus_tag="VQ847_001326"
     CDS             18617..19282
                     /locus_tag="VQ847_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3050663.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19354..20580
                     /locus_tag="VQ847_001327"
     CDS             19354..20580
                     /locus_tag="VQ847_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3050664.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         6466 a         3226 c         4172 g         6808 t
ORIGIN      
        1 gtattattct tcatctggtg tgaggatcat cgggatgatg atcggttcac gttcggtatt
       61 ttcatagagg aaggggcgaa tagcgttgac aatggcacca ttgacagatt gcacgctagc
      121 atccttattt ttcagtgcga tacgaatggc attgaagagg atacgctggc tttggcgaat
      181 caagtcgcca gactctctca tgtagacaaa gcctcggctg aggatgtctg gaccagatag
      241 aatcatctgc gatttgaagt caacagttgc gactgccaga acgacaccgt cttcagatag
      301 atcgcgacga tctttgagga cagctgcgcc aatttcaccg atacgatttc catcgacata
      361 gatatcttgg gcgttgaaat gacctgcgat acgagctgag tcagcagtaa gggcaagcac
      421 atcgccattg ctcatgataa agatattgtc cttctcaaca ccagtatcca ctgctagtcc
      481 agcgtggact ttttgcatgc ggtattcacc gtggacaggc atgaagtatt ttggcttaat
      541 caagcggagc atgagttttt gctcttgctg accaccgtgt ccagatgtat ggatattgtt
      601 cactttaccg tggataactt cgacaccagc ttcagaaata atgttaatca gcttgttgac
      661 gctagtagtg tttccaggga tgggactaga agagaagata acggtatcgc ctggttggag
      721 ttgtacctga cggtgggttc cgttggcgat acgagagagg gctgccatag gttcaccttg
      781 actacctgta cagaggatca gaatctcacc tgcaggatag tctttgattt catttggctc
      841 aataaaggtt cccttaggag ctttgatgta gccaagatcg attccgttga caatggcctt
      901 ttccatagag cgaccaaaga ccgcaatctt gcgcccagtc ttaacagcag cttccgttgc
      961 ttgttggaga cggaagatat ttgaggcgaa ggatgcaaag atgatacgtc cctcgatacc
     1021 ttggataatc ttcatgatgg actggccgac aaccttttca gagttggtaa aggttggaac
     1081 ctcagcattg gtcgagtcag agagcaagca aagcactcca tcttcaccta gggctgccat
     1141 acggtgcaag tccgcaggtt ctccaactgg agtaaagtcg aacttaaagt cacctgtaca
     1201 gatgattttc ccttgaggag tatggatgac aattcccaaa ggttctggaa tagagtgagt
     1261 cgttctaaag aaagttgcct tgagattttt aaaggtcaac tcggtgttgt ggttgatttc
     1321 gtaaagtttg gcgttgcgca agaggccgtg ttcttcgagt ttcccacgga tcaaagccaa
     1381 ggcaagcggt ccagcataaa tagggacatt tgcttgcttg agtaggaacg gaatcccacc
     1441 aatgtggtcc tcgtgtccgt gtgtgattaa aacagccttg acgcggtcga tattgtctac
     1501 gatgtaagag tagtcaggaa tgacatagtc gataccaagc aagtcatctt ctgggaattt
     1561 aatcccagca tcgacgatga taatctcgtc ttggtattca attccgtaag tgtttttccc
     1621 gatttctcct agaccaccga tggcaaaaac gccgacttct tcaggtttaa gagtgtaggc
     1681 catattagaa ctccgtaatt ttgaaggcgc cagtttcttt ttcgtaatcg agcaatttgt
     1741 cagacaagag ttcgatatat tcgatattgt actctgggcg attttcttcg acaagttggc
     1801 gagcagcgat acgaccctca agttctgagc tggcatcgat gtctaggtaa agcgcgcgtg
     1861 ttgtttcacg acgtgggcta cgttcttttg tttcttgata aaaaactttg taaatcatat
     1921 agttcctttc tatttacagg tcagcttatt ccaaactttt agcagagatt tgcttgattt
     1981 cattccattt tgtgtctaga ttgaccttga ttcgttacaa ttatttcaat tataccacaa
     2041 aatgaaaaat tagtaaaaga cggaaacgag aaagttaggg gacgatttct ttggtaagcg
     2101 tttgcaaaaa caaagaaaat gtattatgtt gataacggaa gtgaaattta ttgcttgtca
     2161 taattccata tagattttaa gtcaaggagg ttgccctatg tataacttat ttgcttttgc
     2221 tatcggagtt cgtttgctag cttttatcgt ttttgttgct tgcgtttatg gaggaaatct
     2281 tctatttgcc aaactggaac gatgacaaac caagttcttg aggaaaatta cctttgtgac
     2341 tctctactcg ctttttctcc tcctcgtgac ctatgtcgtt tggtttgtat tttactttgg
     2401 attgccctgc ttatgctggg gttttttgtt tggggatgta gagatagtag atttacgaca
     2461 cgaaaattcc accccatcta tcaagatgag gtggtctttg catttttcta acatgacatg
     2521 acaatggaat tttcaaagct tattattttt atgggagtca ttgttctgct caaaaataga
     2581 gttgaagcat aaaaataaaa caatacaaac agataaatcg aatggtaaag ggatagtagt
     2641 aatgttcaaa tcattgagaa tgctgagcaa actgtaagag atgaagacaa taaaatttat
     2701 ccttctaaaa atgtgtttct tatctagcat gacttaccaa actttttacg aaggtctttt
     2761 ccaatggtat aacctgccat aaataaagcg ataccaacac ctacaccaaa gccacccttg
     2821 atttcttgca attccttatt agaaatttca cgatagttgt tcaaattttt catcatatta
     2881 atctcctcct aaaaaataac cagctgccaa accagaacct ataagtgctg ttccacctgc
     2941 aatagctttc caagatactg ctactccaaa gataaccaag ggagcgagac cgccatcaat
     3001 atctgataat tcattttcag ataaggataa aaattgattg tcaagaatgt caaaatttgt
     3061 cattgaattt tcctcctttt ttcttgttca cttttatatt cggaaaagaa aaggaaaagt
     3121 gagcattttt ttaaattatt tttagttaag tgagggcact cttgtctggg ggcaaagaaa
     3181 attcccatgt gccagctttt gtagtataat agtaagcaga caaaaagata ggaatgtgtt
     3241 atgaaagtat tagcttttga tacgtccagc aaggctcttt ctctcgctat tttagaggat
     3301 aagcagattc ttgccgagat gacgattaat attaagaaaa atcacagtat taccctcatg
     3361 cctgccatcg attttttgat ggcaagtttg gactggacac ccaaggattt ggaccgaatc
     3421 gtggtggctg aagggccagg tagctacaca ggcttgcgaa ttgcggtagc cactgccaag
     3481 actttggctc atactctgaa catcgagtta gttggtatgt ctagcctctt ggctctggta
     3541 ccctaccaac aagaaggctt gttcgtctct ttgatggatg cgcgtcgcaa caatgtttat
     3601 gcaggatttt atgaaaatgc taaacccgtc atgccagaag ctcacttacc ctttgagcga
     3661 gtgattgagt taatcaaggg tgctagtcag gttacctttg tcggagaagt tgcccccttt
     3721 gtggagcaga ttcaagaaca cttgccaagg actaattata aagaaacctt acctaatgca
     3781 gccaatcttg ctcttttagc ttgggacaag gaagcagact ccttgcatga ttttgtgccg
     3841 aattacctca aacgagtcga ggctgaggaa aactggctca agaaccatac cgagtctggt
     3901 gagtcctaca ttaaacgcct atgatagaaa tcaagcgaat tcaacaacag cctgacctag
     3961 ctcaagccat ctacgctgtt atggcagctg tttacctagt cagtccttgg actctggagc
     4021 aaatccaagc agatctgtcc caagaccaga cttggtatgc attggcttat gatggggcag
     4081 aagtgattgg atttctagct gtgcaggaga atctttttga agcagaagtc ctgcaaatcg
     4141 ctgtcaaagg agcttatcag ggtcagggaa ttgcgtcagc cttgtttgct caattgccga
     4201 cagacaagga aattttcctc gaagtcagac agtcaaatca acgagcgcaa gcattttaca
     4261 agaaagaaaa gatggcagtt atcgctgagc gaaaggccta ctaccatgac ccagtcgagg
     4321 acgccattat catgaagaga gaaatagatg aaggatagat atattttagc atttgagaca
     4381 tcctgtgatg agaccagtgt cgccgtcttg aaaaacgacg atgagctctt gtccaatgtc
     4441 attgctagtc aaattgagag tcacaaacgt tttggtggcg tagtgcccga agtagccagt
     4501 cgtcaccatg tcgaggtcat tacagcctgt atcgaggagg cattggcaga agcagggatt
     4561 accgaagagg acgtgacagc tgttgcggtt acctacggac caggcttggt cggagccttg
     4621 ctagttggtt tgtcagctgc caaggccttt gcttgggctc acggacttcc actgattcct
     4681 gttaatcaca tggctgggca cctcatggca gctcagagtg tggagccttt ggagtttccc
     4741 ttgctagccc ttttagtcag tggtgggcac acagagttgg tctatgtttc tgaggctggc
     4801 gattacaaga ttgttgggga gacacgagac gatgcagttg gggaggctta tgacaaggtc
     4861 ggtcgtgtca tgggcttgac ctatcctgca ggtcgtgaga ttgacgatct ggctcatcag
     4921 gggcaggata tttatgattt cccccgtgcc atgattaagg aagataatct ggagttctcc
     4981 ttctcaggtt tgaaatctgc ctttatcaat cttcatcaca atgccgagca aaagggagaa
     5041 agcctgtcta cagaagattt gtgtgcttcc ttccaagcag cagttatgga cattctcatg
     5101 gcaaaaacca agaaggcttt ggagaaatat cctgttaaaa ccctagttgt ggcaggtggt
     5161 gtggcagcca ataaaggtct cagagaacgc ctagcagccg aaatcacaga tgtcaaggtt
     5221 atcatccccc ctctgcgact ctgcggagac aatgcaggta tgattgccta tgccagcgtc
     5281 agcgagtgga acaaagaaaa cttcgcaggc tgggacctca atgccaaacc aagtcttgcc
     5341 tttgatacca tggaataaag agtggctctt tgtcaagtgt agtgggtagg cgaaaagcta
     5401 caatctggag agtacgaaat tcgtactctc ttttttgatg ttcaaagtca tcaaaatccg
     5461 ttttttaaaa ttgttaaagt tccggaaacc aaaggctttg cgcttgataa ccttaatcaa
     5521 attattggtc gcttcaagtt tagcgttgga ataaggcagc ttaagtgcgt tgataatctt
     5581 atctctatcc cttaaaaaag tccaaaagac cgtttgaaaa agcggatgaa ccgttggcag
     5641 ttcttgctca atcaatccaa agaaatggtc ggcattcttc tcttgaaaat gaaagagcag
     5701 gagttgatag agttcgtagt gaacctgtaa tccctcagag taagaaagca gcttatctcg
     5761 tacttcccga tgggttaagt gcattcgaaa cgtgggctga tagaatcgtt tctgacagag
     5821 cttgaagcta tcctggtgta gtaaatcagt ccagtggact gatttagccc gagcctagaa
     5881 acgaaaaagc gagggttcca aaagcgcttg agcgcccgat actccaagga ttttcggtca
     5941 aattggttca tgatttggat tcgtactcgg ttcatagctc ggctcagatg ttggacaatg
     6001 tggaagcggt caagaacaat cttcgccttt ggaaagagtt gcttagcgag ccgataataa
     6061 gggctgtaca tgtccatggt gatgacctcg accagctccc gaacctctct ctgatagcgt
     6121 tggaaatggt ttcgaatcac cgcatgagtt cgtccgtcta aaattgcgag gatggatttg
     6181 gactcaaaat cttgggcaat gaagctcatt ttgctctttt tgaagctata ctcatcccaa
     6241 ctcataactt ttggcaactt ggtccaatcg gtttcaaact taaattccct cagttttcgg
     6301 atgacggtgg aagttgagcc cgccaatctg tgggcaatct cagtcataga ctgcttttca
     6361 aggaggagct gagcgatttt ttgtctcacc atgttggaaa tctggcaatt tttcttgaca
     6421 atggatgttt gagaaacgac caccttaagg caattcttgc actgaaagcg gcgctttttg
     6481 agatgcagta ccgtgggtaa accctgacag tcgagaagcg gaattttaga ggctttctgg
     6541 aagtcgtatt tgatcatctt cccttgacaa tgaggacaag gaggagcggg ggaatccaac
     6601 tttgcctgaa cgactagatg ggtttggtat ttcagaacag acaagatttt gatatttttg
     6661 tcttccaatc cgagcaaatc tgtggtattc ttaagttgtt ccatatgaac cctttctaat
     6721 gagttggtta gacgcttttc attataggtc atatggggct ttttttctac aagaaacgac
     6781 cctataattc ctggggtggg attacccact acagaaatta tagagccaaa gcattccaaa
     6841 gtcttgtctg actctggaat gttttctgtt cacagttgtt ttgtaactgc ctaataagta
     6901 accgcgctat aacgaggtat ctaccgagat tgtcaattct ccagtatact gttataaaaa
     6961 acaaaactgg aggatttttt tatgtccccc ccatcgtccc atcgactgtt ccgtagctgc
     7021 ccaataacgg agtataatca gctgaaacaa gaataggaca aaagtgcctc aagaaaagca
     7081 tcgtaatttg acaatattat tctgagatgt ttttgatgta agcccatatt ttctcaatgg
     7141 gattatactc gggtgaatag gtaggaagtg gtaacagtct atgccctgct ccttacacat
     7201 gttcattctg tgaaaccttg cattgtccat aatgataagg gatggtgtat ctaaagtagg
     7261 tagtaagaat ttttggaagc aagcttcgaa aaagtcactc gtcatcgtat ctttataggt
     7321 catcggagcc atagtatatt gaaacaaaaa agggcattag tacttctata acagtatcgc
     7381 aatctctggt gtgcgttgtc tcgatcttaa ttcaaataat tatatcttct tccagagaga
     7441 ctaactgcct gctcaaggct cgatcatatt cgagataaaa ataggtctca acccctgtct
     7501 cataaatata aataggagtc aggtagctta agtgattcaa ttctttaagg aaccgattta
     7561 ctttttctgg gtcttgttcg cagtaggtac ggctcttttt tagactatat cccatagcct
     7621 ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt tcagtcaaat
     7681 aagcatcggg atgagtttca atatagattt ttaatttatc tctatcaatt ttttcaatta
     7741 atagtggaag tttttttgaa gttagtgtat tgaaacgttt ttatacagtg ctaaaatttg
     7801 aagtgtagtg cagatgtatt tgtaatagta ttatagcaat tctttggaga aggtcgagac
     7861 aagataaaat aggtatcttt gagatataag catgatttac tataaaatta ttgagttatt
     7921 cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt tacaatgcaa
     7981 tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat taaggatata
     8041 gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg tatagatccg
     8101 catataattg gactttgtaa aaagcagatc agaaggatgt ctctatatcc tattttgata
     8161 atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat tgcctatgtt
     8221 gattgtactc aatgttcaaa taattttgaa actgccttac acgttaaaaa tattttaaaa
     8281 ttattaaaaa tccaacttat acactgtcat ggctactcaa ctaattattt tttatatatg
     8341 ttaaaaaaac ttgacaagaa tggatttgga aaggttaaga cagtgataac atgccatgga
     8401 tgggttgaat ataacttaaa aaagaaattc ttgacttatt ttgatttttg gacatattct
     8461 atgggagatg cttttatttg tgtatctgaa actatgaaaa aaagattgga gagtataata
     8521 aaaaaataag aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga
     8581 tgtagtaggt gttcaagact ttaaaaaaga attttgtatt ccaaataaca aaaaatcatt
     8641 tgttatgttg gaaggttgga tccagaaaaa aggccggata gattccttga atttgcagaa
     8701 aaattatttt tagtcagaga agatgtgatt tttattatgg ctggaaatgg tagtatgtgg
     8761 gctgctttga aagaaaaaat ttgctatttg aaatgtagag ataatttcag gttacttggt
     8821 gaaatctatc cagtactata gtttaccaaa tatcggattt attgtatatt ccttctgata
     8881 cagaaggaat atctatgtgt gttttagagt caatgtcaca aggaactccg gttttagcta
     8941 gtaatgttgg cgggttaagt gaaattattg aacatagggt tgatggattt ttatttgaga
     9001 aggaagatgt tgagggagtg tgtgcttgtg ctaatttttt actcaatgat tctgagtatt
     9061 tgaaatatgt aggtgagaat agtaaatcaa aaataagaaa acatttttct gtgcaaaaaa
     9121 tgtttgtaga aaccatgaga gtatatgatg aattattaga gaagagtagt catggatagg
     9181 aatatagatc aagaattagt aagtattata ataccaacac ataataggta tgaatctctg
     9241 attagagctg tgaaaagttg tttacatcaa agttataaaa atatcgaagt tataattatt
     9301 gatgataatt atagtaatgt aaatttaaga aataaaatta tccatcaatt tggctatacc
     9361 aatcatagaa ttaagttaat tttaagtaat gaagatttag gtgcaactaa tgccagaaac
     9421 ataggtatca aaaattctag aggtaagtat atatcatttt tagacgatga tgatgaatat
     9481 atgccagatc gaattttaaa gttgatggct tgttttaaaa agagtagaat gaagaattta
     9541 gctttagttt atagttatgg aataataatt tatccaaatg gtacacgaga agaggagaag
     9601 accgattttg ttggaaatcc cttgtttgtt caaatggttc acaatatagc aggtacgtca
     9661 ttttggttgt gtaaaaaaga ggtgctagaa ttaattaatg gttttgagaa aatagattca
     9721 catcaggacg gtgttgtttt attaaaacta cttgctcaag gataccaaat tgatatagtg
     9781 cgagaattct tggtgaatta ctacgctcac agtaaagaaa acggtatcac tggagtgaca
     9841 caaaaaacaa ttaatgcaga tgaagaatat tataattact gtaggaaata ttttaattta
     9901 ttgagtttca acgagagaat attggttaca aagaaatatt attctttaaa cataaagcgg
     9961 ttactattta ataggagaca aatgcaaggc tttaaaagta atcaagaagg caagagaaga
    10021 aaaaattttt aacgaatttc ttttttaaaa tatatgttat tatatcattt tggttttttc
    10081 tattgtatat atgacaacta tgttcaatta aaatttagaa agtgagaaac tattgtgtat
    10141 actattataa aatcaaatat aaaaaaattt agtttattaa cgatatttat tgttgctggt
    10201 caattattgc taatttatgc agcaactatt aatgctctgg tgttgaatga attaattgcg
    10261 atgaatttag agcggttttt gaaattgtca atctaccaaa tgattgtctg gtgtgggata
    10321 atattccttg actgggtagt gaaaaattat caggttgaag tgatccaaga gtttaatcta
    10381 gagattcgaa atagagttgc cacagacatc tctaactcta cctatcaaga atttcatagt
    10441 aaatcatcag gaacatatct ttcgtggcta aataatgatg ttcagacttt aaatgatcag
    10501 gcttttaaac aacttttttt agtaataaaa ggaatttctg gtactatatt tgcagttgtg
    10561 actcttaatc actatcattg gtcattgact gtagccacct tgttttcatt aatgattatg
    10621 ctacttgtac caaaaatctt tgcatcgaaa atgcgagaag ttagtctaaa tttaactaac
    10681 caaaatgaag cttttttaaa atctagtgag actatattga atggatttga tgtgttagcg
    10741 tccttgaatc ttttatatgt attgcctaag aaaattaaag aagcaggaat tttattaaag
    10801 atggttatac aaagaaagac aactgtagaa acgttagcag gcgctattag cttctttctc
    10861 aatatttttt ttcagatatc tctcgttttt ttaacaggct atcttgcaat aaaaggaata
    10921 gtgaaaattg gtactattga agcaatagga gcactaacag gtgttatttt tacagcgcta
    10981 ggtgaattag gaggtcaatt atcctctatt attggtacga agcctatttt tttaaaattg
    11041 tattcaatta atccaattga gtcaaataaa atgaatgata tcgaaccaaa tgaggtgaat
    11101 agagattttc cgttatatga agcaaaaaat atttgctata agtatggaga taaagaaata
    11161 ttaaaaaact taaatttttg ttttcaacgt aatgaaaagt atttaatttt aggtgaaagt
    11221 ggaagcggga aatctacatt attaaaatta ttgaatggct ttttgagaga ttatagtgga
    11281 gaattgcgat tctgcgggga tgatataaaa aaaacctcct atttaaatat ggtttcgaat
    11341 gttctatatg tagatcaaaa agcttatttg tttgaaggta cgattagaga taatatttta
    11401 ttggaagaaa attatactga tgaagaaata ctacagtctt tagagcaagt tggtttgagt
    11461 gtaaaagatt ttcctaataa cattttagat tattatgttg gtgatgatgg gagattactg
    11521 tcaggagggc agaaacaaaa aattacttta gctagagggc taattagaaa taagaaaata
    11581 gtattaattg acgagggaac ttctgctatc gataggagaa cttcgttagc gattgaacgt
    11641 aagatattag atagagagga tttgactgtc attattgtta cccatgctcc gcatccggaa
    11701 cttaaacaat attttactaa gatatatcaa tttccaaagg attttattta agaatatagg
    11761 ggagggaaac atgagattct attgtgaagc ttatgaggta attactgaag agaaaaaagt
    11821 atactttaat gatattgagt tagaagttaa gtattcctct gtcgaagaat tgtttataat
    11881 atgtgagaaa ttattagata agaaaaaagt atcatttttt tatgtatatg agaaaccctt
    11941 aaggtatctg ttatttgact atatatttct actagttcta gctaaaaaaa tatcccaatc
    12001 ttagatggag tttccaataa gcaagttgat ccaacgttgc tgcatcactt ttctttggaa
    12061 attgaaaaga attttatcga tttttgctat aaaaatatgg atctcatcct aaaaactcaa
    12121 agtatatctt tgtgtcatag agaagagctt attattgtag atgtttcaga tgactctaaa
    12181 tttggtgttt tttacaagcg ttttagaaca ctggttgata aaaataacgg aaaatatgtt
    12241 tgtgtttata atttcagtcg tgtttcagat atactgcaaa actggaaaaa ttattgcaat
    12301 cgaaaatttt cggttacgtt tactgaaagc caatttgaat tatttaagct tttatataat
    12361 caaaaaaatt ttaaaacaat ttcgttgcta tttggaaaaa aattgttgct ggaggaatta
    12421 tctattatag cgatcttact aatatagaat acttttgtat tttttggtgg gatagtatgt
    12481 ttgggaaaga ttctattgga aaatacgtat atgtagaaga gattagtaga tgtcattttt
    12541 tagatagaaa ttattctttt tgttatggtt tacaagatta taaaagtaaa cttattaaat
    12601 attttttaga atagttaatc tattcgagag agataaagaa atatggaaaa tactttattg
    12661 aatatcacag gaagcttcga tatggaaact aggaatctaa ttagttattc tttaactgat
    12721 atctttgaaa cagataaaat aagaattgaa cttcttggag aaatttatta taaaaatata
    12781 aagttggaat tgcatgaatt cgctggattg tataagattt atggaattag cttaataaag
    12841 aatattaccg gaatgttttt aattataatt tttgatacga agacaaaaga attaaaaatt
    12901 tttcaagata taacgacttc atactttaat ttatactata ctgtttatgg aggtgtgttc
    12961 tatatatagt acatctttaa agaaagtgat gaagttatct catgttcccg ttaccttaaa
    13021 taacaaaaaa atacaagaat ttatgagaaa tggatttatt ttagattcaa atactttagt
    13081 aaccgaaatt aataaattag aatatttctc ttacatttct gtaaataata ctcttcgtat
    13141 atgtggtatt gattataatg attcaaacaa ttttactaaa gaacaagtat taaagaattg
    13201 ggactctatg ctacgtgaat ctatattaag agtgtatagt gaagcaggag aggctaatat
    13261 tacactatca tctggttttg attcaaatta tatattatat acattagcga attatacgaa
    13321 ttcttcaatt aatgcatttt gcataggagg agaaaaagga attaatgaga ttcctgaagt
    13381 aactaaaatt gcaaaatttt atggtataaa tttattagtt gatactgtaa tgagcccaag
    13441 atttagaata ttttcccgat atagtatgga gattggaagg aagtctcttt gaatgtggtg
    13501 tcatactgca gtactattta ggcaggttgt tgttccaaaa agggaacaca agtattcttt
    13561 gtggcgagtc agcggatgaa ataatgactt ttaagtatca ttctgtgaac tacaatcaat
    13621 tttgtaatga taaacagaag tcagtatatt ttagttattc cgactatcca ttttatgtta
    13681 caaattcaat tgttttaaag aaaaatagcc tacttttgca tagttttggc attcatccta
    13741 gatatccata taaaatgtct gagattgttg aaatgtctaa aaaaatatca gatctaaacg
    13801 ataaaaaaga atttcacaaa aagaactgtg agttgaggtt tcaagatagt gttcttgata
    13861 acataaatag tgtcccgggt acaactcatt tatttagttg tttaaatatt caaacattag
    13921 taaaaattat tttatatatt tttcgataca acagttgtat gaaaatattt aattttagag
    13981 ataaagagct tatctttttt aataagattg taaatgggct gatacaaaat attgaggaga
    14041 atttagagga tgatattgaa aggatattga aatatttata tatatgttta tttaacgaaa
    14101 tattcattat taagaataag gtgaattttt ttgatgatgt ggaatttaat cagacactta
    14161 gtgagttttt agataaattg tagagggaat ggttatgagt gacaatacta agtatatctt
    14221 tttatctcca catttagatg acgcaatttt ttcctgtggt gattatattt caaaattaac
    14281 ttcagaagga gaaattgtac ttgttattac tatattttct ggttaccctt tgagccaaca
    14341 gctacagccc tctgctaagc aatttcataa gttgtgtaac cttgggaaat atccgattga
    14401 agaaaggaag aaagaagaca ggttagcttg tgaacgtcta caatgtgatt ttagacactt
    14461 atcgtactat gaatgtctct ataggaaaga tagaaatggc aattttctat accgtcatat
    14521 ctatagtaaa ttaaaaaatg aggacacatt aaagaatgat atcataaaag agctgttaat
    14581 gcatttagac gacaaatgtg tcgtatattg tccgctttca cttggtgacc atgttgatca
    14641 tgtttttgtg aatagtattg gaagggcgct tgaatttatg cgttataaag taatatatta
    14701 tgaggacttc ccatatgtaa gtgatagtag tatggttagt tatatgggaa aaactaaaga
    14761 attaaaaatg tatcaagagg aacttgatga aaaacattat attgatagaa tatcatcaat
    14821 attgtgctat aaatctcaga ttttgataat ctggaaatca gttgaaaaac ttttaaacaa
    14881 tattaaagag ttgtatttaa ggaatggggc agcttattct attagatttt ggattaagaa
    14941 ataaggaagt agttttatga atatagcagt aattggtttg gggcatgttg ggctggccta
    15001 cgcgttacta tttgcatcta aatataaagt tgttgcatat gatatagatt ctgtaaaaat
    15061 aaataattta aaaaagggca ctcttccatc taaaaatgaa gagcttatga agtttttttg
    15121 cgagaataac ttaaatatta ctttttttga tacattttct gaaattaaaa ataatattga
    15181 ttattatatt attgcgcttc cgacagatta tgatgagaaa attggtagtt ttaatacata
    15241 tgaaatcgaa caaacggtat cgaagattct gagggtaaaa cctaatggaa agattatttt
    15301 aaagtcaaca gttccgatcg gcttttcaaa caaattaaaa aggctgtttg atacaaaaaa
    15361 tatcattttt gtccctgaat ttttgagaga aggttgttct atatatgata atttatatcc
    15421 aagtcgcata gttgttggag atgagacagt tgaaggaaga aaaattgcag agttgttcct
    15481 ttcgattagt actcatagta ctgccaatat taaaaatgtt atgttagttt ctcctactga
    15541 agcagaagca attaagcttt tttctaacac attcttagct ctccgtgttg ctttttttaa
    15601 tgaactagat tcttttgctg agaggagaag tttaaatgct gaagttgtaa taaaaggtgt
    15661 ttgtttagat ccaagaattg gaaattttta taataatcct tcttttggat ttggaggata
    15721 ttgtcttccc aaagatacta aacaattaaa aaaagaattt atagaaataa atgccccagt
    15781 gatagaagcg attgatattt caaacacaaa tagaaaacag ttcatagtta aacaaatatt
    15841 ggaacgaaag ccaaagatag taggaatata taaattgggg atgaaatata attcagataa
    15901 ttacaaagag tcagctattt taagtataat taatgaacta ttgattgtcg gtataaaaat
    15961 tttagtatat gaaccaaatt taaacgttag tatagataac gtaatttttg aaaagaattt
    16021 tgaactattt ataaaacaaa gtgatctaat tgttgcaaat agatgggata gggaccttga
    16081 agcttataaa gataaagttt acacaagggg gatctggata agagattaac tattgatatt
    16141 aaaaaggcaa taatttataa aatttgtaca aaaaaatgtt aaattttcac attttcatag
    16201 tatactgttt aatagaaagt aggttctttg taaccgctcc attataaaat cctttcactc
    16261 ttccggtata ctattaggaa aaacataact ggaggatatt ttgagctcac acctcatcgt
    16321 tccagtggct gttccccaag ctcgtgtact gcccaaaaaa gttagacatt ctatttagaa
    16381 cgaggattga gttctgtatt gtacaaggct cggtcctttt agagtcagct taaggctggc
    16441 tttttcaatc accaaagtgt cagaatgttt tgacaaatga acacaaataa tgatataata
    16501 tgcaaaagct aggaggtggt aggatgattg aaaaaatgga actgggggaa ttttacaagg
    16561 aattgcgctt ggcgagaaag ctcaagcagt cagatgtggc ttgtgctgga ctaacagcct
    16621 ctcagttgtc caagtttgaa ctaggacagt ctatgctgtc tgcagacaag ctgatcctag
    16681 ccatccaagg gatcaatatg aattttgatg agtttgggca caaactcaac aactatcaag
    16741 aatctccaca tatgcgaatt ggtagaaggg ttgtggattg cttttcccat caggatatag
    16801 ctgctttaga gcagctattg gaggaagtcg atcaagaaca gatggcgcag acctatcgtc
    16861 gtttgaatgc cattgtgatt aaaaatgcac tccattcctt agataaaagc tacccgctaa
    16921 cagaggagga tagcgagttt ttgactacct acctctacgc tattgagtct tggacctggt
    16981 ttgaactcta tcttttttgc aatactatgc ccttcttgag caatcaagat ctgatctttt
    17041 tatcaacctc cttactcgaa aaatccaagg aatttaaaga gttagtacac aatcgatggt
    17101 atatgaaaag tggttatctt aatatcatct cagaacttat ggagcgcaag ctattttctt
    17161 atattccaat ctttgaagct gagctggagc gcatgctccg tccatacgat gtttttgaaa
    17221 aagtattgtg gcagttttta aagaaaatgc agatttttct tcaaaccaaa ggaagcaatc
    17281 aaaaagagat tgaacacttt atccaatctc tgcaagtatt agaaaatcca caattgacag
    17341 ccctttttga attgcgtttg cagcaataca aagagcttat cgattagtta gaaatgggaa
    17401 aaagataata atatcagcaa cgatcgtcaa taatgttaaa acttgtttct tcatattact
    17461 tccctcctca ttagtaataa ctttattata ccagggaaat aatcaaatct accaaaatcg
    17521 caaatctgaa atttctataa gaaaaaatat caaatatgcg attttctaaa ataagccaat
    17581 ttccgtgtta tactgtcctt gtaaaacatt tgaagcaaat cctaggtcgc agaagtggtt
    17641 tacaaatgaa gataattgaa ggagtgtaaa agatgttaaa tttacaattt gcagaaacaa
    17701 tggaattgac agaagctgag ttgcaagatg ttagaggagg caacctcgta aattctatgg
    17761 gaggtggtgg aagaagtggt atatctggtt ggggcgtccc aggaatttac cctggttggg
    17821 gcaatcaagg gatgagtcct aatcgtggag cttttgattg gactatagat ttagcagatg
    17881 gattgtttgg ccgccgtaga agataggctc ttataggaga taataggatg aagaaaatga
    17941 aagaagtgaa atttcaccta gcaactggct tgttgatttt gacttattac ctcattttta
    18001 atgtcacatc agacttagat tttatggttg ctttgtctga taatatgtac tatgtgttcc
    18061 aagttttatt ggtacttatt ctgggaacta tagctacaat tgcttttgtc aaaagtgaac
    18121 attggaaaga gtgtggtcgt ttccagtttc gttggtctta cctgggtgtt ttccttcttt
    18181 cttttttctt attgttcgtg tgggcaaatc taacaaccta tatctttcct cgtacccaga
    18241 atggaagtac agtcgtagaa gtagccacca gtttaacagg aattagctat tttgttacgc
    18301 gaatacttta tactagtatt atcgcacctg tatcagaaga ggttgtttgt cgtggtcttt
    18361 tgatgacaag tttatctaaa gttaatagat actatcttga tgttcttgtt tccgctgcca
    18421 tatttggcgc tatgcatgtt ttgcagtatg gttggataac gacagatttc ataaagtatt
    18481 ttggaatggg cttgatattt tgtatgatgt ttcgctacac ccgatccatc tattgggcta
    18541 tagctctgca tgcttcatgg aatagcttct tactcattgt tactttattg gtatttggat
    18601 attagaaagg tgatatatga aaaagataat ctcacaccgc tactttatta tagtttttct
    18661 actagttatt gctgaccaga agttcagtgt tttagtttta cgcagcgacc ttgttgctgg
    18721 gctatctgac tttgcctatt atctgtcgga tatgatgttg aattttcttg tggttttatt
    18781 tgctcttatt gctatgattt ggtcggggaa atggcagaaa atcaatagta gaaagtttaa
    18841 aggatcctat cttttctatt ccttcctagc tctgcttgct tttgttgctt ggaattttgt
    18901 cacctttttt cttttcccac ctactcgaaa tgaaatttct tatcaacatg ctgctcctac
    18961 ttttacagga gctacggcat ttttgatgta ttttttttat cctgtgattg caggtcccat
    19021 ttttgaagac atgatttatc gtggattagt gatgactgct ctggaaaaag gaaagaaatg
    19081 ggggctagat gtacttggtt ccgctgtttt atttggggtc tcgcacatta gtaatcacgg
    19141 ttgggtcttg acagactttg tcttctatat gggtggaggt cttatatttg cagtcttatt
    19201 tagaatgaca aagtcaattt attggcctat tggactgcat atagtctaca atggtattgg
    19261 tcagcttttg atgttactgt aattttggtt gttagtagta tcgcggtcta ttcttgggga
    19321 aagattccca tttgaattta aaaaggagtt gtaatgaaag tatttcttca aaatagagat
    19381 tttaggcaat taactatcaa ccagtggatt tcaacgcttg gggatacgat tttttatctg
    19441 gccttcctga attatgtggc agatgcgtct tttgcccctt tggcgatttt acttatcacg
    19501 atttcagaaa cccttcccca agttctacaa atctttctgg gagttttggc ggattttcaa
    19561 catcatcgtg tcttgaaata cacagtcatt agttttacaa aatttttgct ttactctata
    19621 gtgtccctat cgctttcagg gcagtctttt tccttgttgc tagtaacctt tatttgtctg
    19681 attaacctct tgtctgacac attgagttat ttttcaggcg ccatgctcac tccgattttc
    19741 attagaatta ttgggcaaga tcatctggca gaagctattg gatttaaaca gtcaactgtt
    19801 agtttagtga aaacaatcag taatatccta ggaggagtct tactaggtat tctatccatc
    19861 cagtttattt ccttactgaa cgctcttacc tttttaatcg catttttagg tatcctcttc
    19921 ataaaaactg acctcttgaa agtagaaaaa acgattagct atcaagaagg actctctgta
    19981 aaatcctttt gccagcattt gctccaatca tcgaaattga tatggaatat gaataaggtg
    20041 ctcttggttt tgtttattat ctctactagt caagcagtga taaatgttac agttcctgtc
    20101 tctactctat ttttgaggaa tcaacccttt ttgaatttac aaacaggtca atctcttgcc
    20161 ttgctatcca cttttgaact gtcagccctg attgtcggaa gccttgtaag tggctatctg
    20221 caacatacca tttccataaa aacagctctc tatgcctcac ttgtcatcca gttgcttctt
    20281 ctagtaggat ttgccacagt tcgttttgac tggattctca tctttagtac cttggatgcc
    20341 tttttcgcag gtgttctctc tcctagattg caagaactcg tctttaaaca aatacctgag
    20401 gagtcaatgg gagcagttca atcttctatc agtgccatta cggttgtttt acctagctta
    20461 tttacaatat ctttggtaac cattgctact agctttggaa ctctggcagt tagctttgtt
    20521 ttattgctat ttcttctagt tgcctttgtt atgcttctga atattcgtga aagtatttag
    20581 tggagaattt ctataatata tgtttgagac tggattgcca gtctttttat gatggtcaaa
    20641 atcaacagac ttttttctct tttctgaatg tg
//
LOCUS       DAVBNN010000034        20670 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBNN010000034 DAVBNN010000000
VERSION     DAVBNN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.034"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            175..2157
                     /locus_tag="VQ847_001328"
     CDS             175..2157
                     /locus_tag="VQ847_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3050665.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2457..7760
                     /locus_tag="VQ847_001329"
     CDS             2457..7760
                     /locus_tag="VQ847_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3050666.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7927..10086)
                     /locus_tag="VQ847_001330"
     CDS             complement(7927..10086)
                     /locus_tag="VQ847_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3050667.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10083..10679)
                     /gene="recU"
                     /locus_tag="VQ847_001331"
     CDS             complement(10083..10679)
                     /gene="recU"
                     /locus_tag="VQ847_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3050668.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10745..11272
                     /locus_tag="VQ847_001332"
     CDS             10745..11272
                     /locus_tag="VQ847_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3050669.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11342..11671
                     /gene="gpsB"
                     /locus_tag="VQ847_001333"
     CDS             11342..11671
                     /gene="gpsB"
                     /locus_tag="VQ847_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3050670.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11692..12072
                     /gene="rnpB"
                     /locus_tag="VQ847_001334"
     ncRNA           11692..12072
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ847_001334"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12157..13314
                     /locus_tag="VQ847_001335"
     CDS             12157..13314
                     /locus_tag="VQ847_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3050671.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13327..14721
                     /gene="mapZ"
                     /locus_tag="VQ847_001336"
     CDS             13327..14721
                     /gene="mapZ"
                     /locus_tag="VQ847_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3050672.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14797..16221
                     /gene="gndA"
                     /locus_tag="VQ847_001337"
     CDS             14797..16221
                     /gene="gndA"
                     /locus_tag="VQ847_001337"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3050673.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16233..16922
                     /locus_tag="VQ847_001338"
     CDS             16233..16922
                     /locus_tag="VQ847_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3050674.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17020..18039
                     /gene="cbpC"
                     /locus_tag="VQ847_001339"
     CDS             17020..18039
                     /gene="cbpC"
                     /locus_tag="VQ847_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3050675.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18157..19389)
                     /locus_tag="VQ847_001340"
     CDS             complement(18157..19389)
                     /locus_tag="VQ847_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3050676.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19549..20019)
                     /locus_tag="VQ847_001341"
     CDS             complement(19549..20019)
                     /locus_tag="VQ847_001341"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050677.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20186..20596)
                     /locus_tag="VQ847_001342"
     CDS             complement(20186..20596)
                     /locus_tag="VQ847_001342"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050678.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6424 a         3743 c         4636 g         5867 t
ORIGIN      
        1 cgtgagttct ctagtctgga gatttttcaa tagacttcgt tattgggcgg ttacgatatt
       61 catatttttt gcaaagatgt tgtttgaaaa ataattttca aaaattctga aaattctgtt
      121 gacatctttc tgaaaagagt ctataatgga gagaaagttt taaaggagaa aatgatgaaa
      181 agttcaaaac tatttgccct tgcgggcgtg acattattgg cggcgactac tttagctgca
      241 tgctctggat caggttcaag tactaaaggt gagaagacat tctcatacat ttatgagaca
      301 gaccctgata acctcaacta tttgacaact gctaaggctg cgacagcaaa tattaccagt
      361 aacgtggttg atggtttgct agaaaatgat cgctacggga actttgtgcc gtctatggct
      421 gaggattggt ctgtatccaa ggatggattg acttacactt atactatccg taaggatgca
      481 aaatggtata cttctgaagg tgaagaatac gcggcagtca aagctcaaga ctttgtaaca
      541 ggactaaaat atgctgctga taaaaaatca gatgctcttt accttgttca agaatcaatc
      601 aaagggttgg atgcctatgt aaaaggggaa atcaaagatt tctcacaagt aggaattaag
      661 gctctggatg aacagacagt tcagtacact ttgaacaaac cagaaagctt ctggaattct
      721 aagacaacca tgggtgtgct tgcgccagtt aatgaagagt ttttgaattc aaaaggagat
      781 gattttgcca aagctacgga tccaagtagt ctcttgtata acggtcctta tttgttgaaa
      841 tccattgtga ccaaatcctc tgttgaattt gcgaaaaatc cgaactactg ggataaggac
      901 aatgtgcatg ttgacaaagt taaattgtca ttctgggatg gtcaagatac cagcaaacct
      961 gcagaaaact ttaaagatgg tagccttaca gcagctcgtc tctatccaac aagtgcaagt
     1021 ttcgcagagc ttgagaagag tatgaaggac aatattgtct atactcaaca agactctatt
     1081 acgtatctag ttggtacaaa tattgaccgt cagtcctata aatacacatc taagaccagc
     1141 gacgaacaaa aggcatcgac taaaaaggct ctcttaaaca aggatttccg tcaggctatt
     1201 gcctttggat ttgaccgtac agcctatgcc tctcagttga atggacaaac tggagcaagt
     1261 aaaatcttgc gtaatctctt tgtgccacca acatttgttc aagcagatgg taaaaacttt
     1321 ggcgatatgg tcaaagagaa attggtcact tatggggatg aatggaagga tgttaatctt
     1381 gcagattctc aggatggtct ttacaatcca gaaaaagcca aggctgaatt tgctaaagct
     1441 aaatcagcct tacaagcaga aggagtccaa ttcccaattc atttggatat gccagttgac
     1501 cagacagcaa ctacaaaagt tcagcgcgtc caatctatga aacaatcctt ggaagcaact
     1561 ttaggagctg ataatgtcat tattgatatc caacaactac aaaaagacga agtaaacaat
     1621 attacatatt ttgctgaaaa tgctgctggc gaagattggg atttatcaga taatgtcggt
     1681 tggggtccag actttgccga tccatcaacc taccttgata tcatcaaacc atctgtagga
     1741 gaaagtacta aaacatattt agggtttgac tcaggggaag ataatgtagc tgctaaaaaa
     1801 gtaggtctat atgactacga aaaattggtt actgaggctg gtgatgaggc tacagatgtt
     1861 gctaaacgct atgataaata cgctgcagcc caagcttggt tgacagatag tgctttgatt
     1921 attccaacta catctcgtac agggcgtcca atcttgtcta agatggtacc atttacaata
     1981 ccatttgcat tgtcaggaaa taaaggtaca agtgaaccag tcttgtataa atacttggaa
     2041 cttcaagaca aggcagtcac tgtagatgaa taccaaaaag ctcaggaaaa atggatgaaa
     2101 gaaaaagaag agtctaataa aaaggctcaa gaagatctcg caaaacatgt gaaataactg
     2161 ttgcaaaata taagaaagga tttagtattt ctcttgaatg ctgaatcctt ttttacattt
     2221 gtaaagaaag cttctaaatg tactgacccc caaaagttgg agcctctttt tgtcagaata
     2281 gagaaaattt ttgttaattt tacttgtttc ctattgcttt ctcagttatt atttgttata
     2341 ttaaaagtat aattattttt tatttatcag ggttaagcat tgcactttca gaggaaggag
     2401 tattttttaa aaaggaaatg taaacgcttg ctaaaaatga aaggatttag aagtttatga
     2461 ataaaggatt atttgaaaaa cgttgtaaat atagtattcg gaaattttca ttaggtgttg
     2521 cttctgttat gattggagct gcattctttg ggacaagtcc ggttcttgca gatagcgtgc
     2581 agtctggttc cacggcgaac ttaccagctg atttagctac tgctcttgca acagcaaaag
     2641 agaatgatgg acgtgatttt gaagcgccta aggtgggaga agaccaaggt tctccagaag
     2701 ttacagatgg acctaagaca gaagaagaac tattagcact tgaaaaagaa aaaccggctg
     2761 aagaaaaacc aaaagaggat aaacctgcag ctgctaaacc tgaaacacct aagacggtaa
     2821 cccctgaatg gaaaacggta gagaaaaaag aacaaaaggg aacagtcact atccgagaag
     2881 aaaaaggtgt ccgctacaac caactatcct caactgctca aaatgataac gcaggtaaac
     2941 cagccctgtt tgaaaagaag ggcttgaccg ttgatgccaa tggaaatgca actgttgatt
     3001 taaccttcaa agatgattct gaaaagggca aatcacgctt tggtgtcttc ttgaaattta
     3061 aagataccaa taataatgtt tttgtcggtt atgacaagga tggctggttc tgggagtata
     3121 aatctccaac aactagcact tggtatagag gtagtcgtgt tgctgctcct gaaacaggat
     3181 caacaaaccg tctctctatc actctcaagt cagacggtca gctaaatgcc agcaataacg
     3241 atgtcaatct ctttgacaca gtgactctac cagctgcggt caatgaccat cttaaaaatg
     3301 agaagaagat ccttctcaag gcgggctctt atgacgatga gcgaacagtt gttagcgtta
     3361 aaacggataa ccaagagggg gtaaaaacag aggatacccc tgctgaaaaa gaaacaggtc
     3421 ctgaagttga tgatagcaag gtgacttatg acacgattca gtctaaggtc ctcaaagcag
     3481 tgattgacca agccttccct cgtgtcaagg aatacacctt gaatggacat actttgccag
     3541 gacaggtgca acagttcaac caagtcttta tcaataacca ccgaatcacc cctgaagtca
     3601 cttataagaa aatcaatgag acaacagcag agtacttgat gaagcttcgc gatgatgctc
     3661 acttaatcaa tgcggaaatg acagtacgct tgcaagttgt ggacaatcaa ttgcactttg
     3721 atgtgaccaa gattgtcaac cacaatcaag tcactccagg tcaaaagatt gatgacgaaa
     3781 gaaaactact ttcttctatt agtttcctcg gcaatgcttt agtctctgtt tctagtgatc
     3841 aaactggtgc taagtttgat ggggcaacca tgtcaaacaa tacgcatgtc agcggagatg
     3901 atcatatcga tgtaaccaat ccaatgaagg atttggctaa gggttacatg tatggatttg
     3961 tttctacaga taagcttgct gctggtgttt ggagtaactc tcaaaacagc tatggtggtg
     4021 gttcgaatga ctggactcgt ttgacagctt ataaagaaac agtcggaaat gccaactatg
     4081 taggaatcca cagctctgaa tggcaatggg aaaaagctta taagggcatt gttttcccag
     4141 aatacacgaa ggaacttcca agtgctaagg ttgttatcac tgaagatgcc aatgcagaca
     4201 agaacgttga ttggcaagat ggtgccattg cttatcgtag cattatgaac aatcctcaag
     4261 gttgggaaaa agttaaggat atcacagctt accgtatcgc gatgaacttt ggttctcaag
     4321 cacaaaaccc attccttatg accttggatg gtatcaagaa aatcaatctc catacagatg
     4381 gtcttgggca aggtgttctc cttaaaggat atggtagcga aggccatgac tctggtcact
     4441 tgaactatgc tgatattggt aagcgtatcg gtggtgtcga agacttcaag accctaattg
     4501 agaaggctaa gaaatatgga gctcatctag gtatccacgt taacgcttca gaaacttatc
     4561 ctgagtctaa atacttcaat gaaaaaattc tccgtaagaa tccagatgga agctatagct
     4621 atggttggaa ctggctagat caaggtatca acattgatgc tgcctatgac ctagctcatg
     4681 gtcgtttggc acgttgggaa gatttgaaga aaaaacttgg tgacggtctc gactttatct
     4741 atgtggacgt ttggggtaat ggtcaatcag gtgataacgg tgcctgggct acccacgttc
     4801 ttgctaaaga aattaacaaa caaggctggc gctttgcgat cgagtggggc catggtggtg
     4861 agtacgactc taccttccat cactgggcag ctgacttgac ctacggtggc tacaccaata
     4921 aaggtatcaa cagtgccatc acccgcttta tccgtaacca ccaaaaagat gcttgggtag
     4981 gggactacag aagttatggt ggtgcagcca actatccact gctaggtggc tacagcatga
     5041 aagactttga aggctggcaa ggaagaagtg actacaatgg ctatgtgact aacctctttg
     5101 ctcatgacgt catgactaag tacttccaac acttcactgt aagtaaatgg gaaaatggta
     5161 caccggtgac tatgaccgat aacggtagca cctataaatg gactccagaa atgcgagtgg
     5221 agttggtaga tgctgacaat aataaagtag ttgtaactcg taagtcaaat gatgtcaata
     5281 gcccacaata tcgcgaacgt acagtaacgc tcaacggacg tgtcatccaa gatggttcag
     5341 cttacttgac tccttggaac tgggatgcaa atggtaagaa actttctact gagaaggaaa
     5401 agatgtacta cttcaatacg caggccggta caacaacttg gacccttcca agcgattggg
     5461 caaagagcaa ggtttacctt tacaagctaa ctgaccaagg taagacagaa gagcaagaac
     5521 taactgtaaa agatggtaaa attaccctag atcttctagc aaatcaacca tacgttctct
     5581 atcgttcgaa acaaaccaat cctgaaatgt catggagtga aggcatgcac atctatgacc
     5641 aaggatttaa tagcggtacc ttgaaacatt ggaccatttc aggcgatgct tctaaggcag
     5701 aaattgtcaa gtctcaaggg gcaaacgata tgcttcgtat tcaaggaaac aaagaaaaag
     5761 ttagtctcac tcagaaatta actggcttga aaccaaatac caagtatgcc gtttatgtcg
     5821 gtgtcgataa ccgtagtaat gccaaggcga tcatcactgt aaacactggt gaaaaagaag
     5881 tgactactta taccaataag tctctcgctc tcaactatgt taaggcctac gcccacaata
     5941 cacgtcgtga caatgctaca gttgacgata caagttactt ccaaaacatg tacgccttct
     6001 ttacaactgg atcggacgtc tcaaatgtta ctctgacatt gagtcgtgaa gctggtgatg
     6061 aagcaactta ctttgatgaa attcgtacct ttgaaaacaa ttcaagcatg tacggagaca
     6121 agcatgatac aggtcaagga accttcaagc aagactttga aaatgttgct cagggtatct
     6181 tcccatttgt agtgggtggt gtcgaaggtg tcgaagacaa ccgcactcac ttgtctgaaa
     6241 aacacgatcc atatacacaa cgtggttgga acggtaagaa agttgatgat gttatcgaag
     6301 gaaattggtc actcaagaca aatggactag tgagccgtcg taacttggtt taccaaacta
     6361 ttccgcaaaa cttccgtttt gaagcaggta agacctaccg tgtaaccttt gaatacgaag
     6421 caggttcaga caatacctat gcttttgtag tcggtaaggg agaattccag tcaggtcgtc
     6481 gtggtactca agcaagcaac ttggaaatgc atgaattgcc aaatacttgg acagattcta
     6541 agaaagccaa gaaggcaacc ttcctcgtga caggtgcaga aacaggggat acttgggtag
     6601 gtatctactc aactggaaat gcaagtaata ctcgtggtga ttctggtgga aatgccaact
     6661 tccgtggtta taacgacttc atgatggata atcttcaaat cgaagaaatt accctaacag
     6721 gtaatatgtt gacagaaaat gctctgaaga actacttgcc aacggttgcc atgactaact
     6781 acaccaaaga gtctatggat gctttgaaag aggcggtctt taaccttagt caggccgatg
     6841 atgatatcag tgtggaagaa gcgcgtgcag agattgccaa gattgaaacc ttgaagaatg
     6901 ctttggttca gaagaaaacg gctttggtag cagatgactt tgcaagtctt acagctcctg
     6961 ctcaggctca agaaggtctt gcaaatgcct ttgatggaaa cttatctagt ctatggcata
     7021 catcttggaa tggtggagat gtaggcaagc ctgcaaccat ggtcttgaaa gaaccaactg
     7081 aaatcactgg acttcgttat gttccacgtg gatcaggttc aaatggtaac ttgcgtgatg
     7141 tgaaacttgt tgtgacagat gagtctggca aggagcatac ctttactgca actgattggc
     7201 cagataacaa taagccaaaa gacattgatt ttggtaagac aattaaggct aagaaaattg
     7261 tccttacagg tactaagact tacggagatg gtggcgataa ataccaatct gcagcggaac
     7321 tcatctttac tcgtccacag gtagcagaaa cacctcttga cttgtcaggc tatgaagcag
     7381 ctttgactaa ggctcagaaa ttaacagaca aagacaatca agaggaagta gctagcgttc
     7441 aggcaagcat gaaatatgcg acggataacc atctcttgac ggaaagaatg gtggaatact
     7501 ttgcagatta tctcaaccaa ttaaaagatt ctgctacgaa accagatgct ccaactgtag
     7561 agaaacctga gtttaaactt agctctttag cttccgagca aggtaagacg ccagattata
     7621 agcaagaaat agctagacca gaaacacctg aacaaatctt gccagcaaca ggtgagagtc
     7681 aatctgacac agccctcttc ctagcaggtg ttagcctagc cctatctgct ctctttgtag
     7741 taaaaacgaa gaaagactag tatttagtaa aacctcttaa caagattacg gaagcagtct
     7801 ctatcttttc caatgaggtt tatagtacag aaaaagcctg agaagatgtc ttctcaggct
     7861 tttgttaagc acataaatac aatagtgcta tgaaaaaatc acccagaaaa atctgggtga
     7921 taaatgttat ggttgtgctg attgaggatt ctgattttgt tgatcagggg ttgtatttga
     7981 ttgttgcgta ttattgttag gattggtagt cgtactatta tttgtgcttg gagtggttga
     8041 gctagactgt gaagttgaac tatctgatga tgagcttgaa ctttcagttg atgggggttg
     8101 ttgtggagca ggtgagctcc acgtagaacg agcaccattt ttaaatacga attctccatt
     8161 tctgtagagc ccctctggta tattccaatc ctctggattg cttccttcag acaggtaggt
     8221 catcatagag cggtaaactt tggcagcgac cgtaaggcca ttgcctacaa gtggtgtcag
     8281 acggttagaa tagcctgtcc atacagccat tgaatattta cgcgtatagc cagcaaatag
     8341 ttcatcaggt gctacaaatt gagaggtctt gatgtggttt tcaatttcct cgtctgtata
     8401 gttagaggtt cctgttttac cagcctgagg gagccaagca agataggcat ttcgtccagt
     8461 tccataactc aagactgttt tcatcatgtc ggtcatcata taggctgtcg tttccttcat
     8521 ggcacgagtt ccgacattag agaactcttt ttcactccca tcactaaaga cgactttatg
     8581 gatatacatt ggtttatagt aagttccacc atttgcaaag gcagcgtaag cagcagccat
     8641 cttttcacta cttgctccat attttttgtc tgattcggtt gtgttacttg aaatggcatt
     8701 tgagtagtga atacttgggt agtcgattcc gagaccattt aggaaagtct tggcgcggtt
     8761 gagtccgacc ttgtttagag tttccacggc tgggacgttt cgcgattgtt gcagggcgta
     8821 ttgcaaggtg atgttgccaa agtagcccct atcccagtta taaacaggag tatttgtccc
     8881 agggtagtta tagggctcat cgtgaacgat agtagcagtt gaatcgtaga caccgtactc
     8941 caaggcagga gcatagtctg tgatcggttt catagttgat ccccagtcgc ggtttgtttc
     9001 tactgcttgg ttaattccga aggaaacatt acttgactga tggcgtgctc ctagctgggc
     9061 aatgacttta ccgttagaaa catcaacaat ggtagaagcg acttgcaatt catcgtctgg
     9121 ataggcaacg tattcgtctg tattgtaaat atcccacaga tgtttttgag cttcttggtc
     9181 tacatttgtg tagacatcca tcccagttgt gagcaggtta tagcctgttt cttcttcaac
     9241 ttgattgatg acttccttga ggtaattatc catgtaagca gggtaattac ttgctgattt
     9301 gagactttgt agtccatcag taattggtgt attgactgct ttctcatact gttcagcaga
     9361 gatgtagcct tgatttttca tttcagataa gaccaagttt cggcggtctt gggctgcttc
     9421 tggatgtgaa taggggtcat attggtttgg tgcctgaggc attccagcca gcaaggctaa
     9481 ctgaggtaaa cttaaattat tgaggtcttt accatagtag ttttgagctg ctgtctgcat
     9541 tccatagttc ccattagaca tgtagacctt atttatatag taggtcaaga tttcttgctt
     9601 ggttgctttt tgttctaact gaatcgctaa ccaagcttcc tgagccttac gagaaatagt
     9661 ctggtcggaa gtcgaagttg aaaagtaagt caacttaatc aactgttgag tgagagttga
     9721 tccaccttgg agggaattgc tttgcagatt gcgcaagaaa gctcccagga tacggatggt
     9781 atcaatcccc ctgtggtcga agaagcgatg gtcttcgata gaaacgattg ccttaaccaa
     9841 atctgtggga atatcattag cttgggcatt gacgcggcgt tcagaaccca agtcagcaat
     9901 gagttgattt ttattgtcgt agattttact agaagttgtt gcaactagtt tactctcgga
     9961 taggctagga gccttgctaa cgtagtagaa aaaaactcct ccgcctaaga caatggctgc
    10021 gataaccaag cttaagaagc taatgctcag atacttgatt aggcgcagaa tcgttggttt
    10081 gttcatcttg ttttaccacc taataaatgt tctttgataa cattgagata aggaatttga
    10141 gggaaggcac cagccttgat ttcatatcca tattctcgaa tatattcaag tggcattgat
    10201 ttttgtctct tatcttgatg atagaagcga atcaaatcga atgccggcaa taagtaggtt
    10261 tcttgctgag aagaaaagtg aagaaggaca aagcagattc cttgttgggc aaggacttgt
    10321 tccatatgct gaatctgatg tggatgaaaa tttttcatcg gaatcgcacg tttttgtttt
    10381 gtttccttga cttcaaagtc gatgtaatat ccattataaa cgccagaata gtccgtcgtt
    10441 gaagcttgtc gaaaataggc ttcaacaatc ttggcacgac ttcgttgtgg atagtccact
    10501 tgtacgattt gaataggagt tggtttctta tgtataacag ccaagccctg agacaaatag
    10561 tagtcgttgg tagcattgat catcttttca aaagacattc ctcgatttgc gaaatttttg
    10621 ggttgagaaa gagatgtttg tcttttttgt gatgaaactt tatgtggata gttgaccata
    10681 attctcctta ttggtacaat aacatcactt tattatacca taatttgcac agaaagggtt
    10741 aaaaatggct acagctttgg ttttaggcta ttctgctttt gatttgggtt tattttctga
    10801 taaggatcct cgtcttaaat tgattaaaaa agcgatacgt aaagatttag aggctatggc
    10861 agcagatggg gtgtcttggc ttgtgtttac agggagtttg ggttttgaat attgggtttt
    10921 agaggttgct caggagatga aaaccgaata cggtttccag ttggccacca tttttgcttt
    10981 tgaaacccat ggggaaaatt ggaatgaagg caatcagatg aaactgagtc gctttaagca
    11041 ggtagacttt gtcaaatatg cttatcctcg ctatgaacac aaggggcagt taagagatta
    11101 ccagcagttt ttgctggaaa acacgactag ttcctatctt ttttatgatg aagaaaatga
    11161 aacaaaacta gcttattttt accaaaagat gaaaaatcaa gaggactatt ttataaagag
    11221 attaacattt gatgaattaa atgaacttgc tgaaaatttt tccgaaaatt gaagctttga
    11281 ccttgatttt tgtttgcctt tttttatata ataatactag caagcgagaa tggagagaga
    11341 catggcaagt attatttttt cagcgaaaga tatttttgaa caagagtttg gacgtgaagt
    11401 ccgtggctat aataaagtag aagttgacga gtttttagac gatgtcatca aggactatga
    11461 aacctatgct gccttggtca agtcacttcg tcaggaaatt gcggatttga aggaagaatt
    11521 aactcgtaaa ccgaaacctt caccagttca agcagaaccc cttgaagcgg caattacaag
    11581 ttctatgacg aattttgata ttttgaaacg cctgaataga ttggaaaaag aagtttttgg
    11641 taaacaaatt ttagataact cagattttta agtagttatt tgagatgtgc aatttttgga
    11701 taatcgcgtg aggagaattg cttctcatga ggaaagtcca tgctagcaca ggctgtgatg
    11761 cctgtagtgt ttgtgctagg cgaaaccata agcctaggga cgagaaatcg ttacggcagt
    11821 tgaaatggct aagtccttgg ataggccaga gtaggcttga aagtgccaca gtgacggagt
    11881 ctttctggaa acagagagag tggaacgcgg taaacccctc aagctagcaa cccaaatttt
    11941 ggtcggggca tggagtacgc ggaaacgaac gtagtattct gactgctatc agctagagct
    12001 gttagtggta gacagatgat tatcgaagga agtggtccta gtcacttctg gaacaaaaca
    12061 tggcttatag aaaattgcat ataggttggg gctgagaaat tttctcaacc tcatttttta
    12121 aagtggacat atagaaaggt cttgcaagac tgtaacatga aaaaagaatt taatttaatt
    12181 gcaactgtgg cagcagggct tgaggctgtc gttggtcgtg aagtgcgaga gttgggctac
    12241 gattgtcagg ttgaaaatgg acgtgttcgt tttcaaggag acgtgagagc tattatcgaa
    12301 accaaccttt ggcttcgggc agcagatcgt atcaaaatta tcgtaggaac gttcccagct
    12361 aagacttttg aagagctatt tcagggagtt ttcgctttag attgggaaaa ttatttacca
    12421 cttggagctc ggttcccgat ttcaaaagct aaatgtgtta agtccaaact tcacaatgag
    12481 cccagtgttc aggctatttc taagaaagct gttgtcaaga aattgcagaa acactatgct
    12541 cgcccagaag gggttcctct gatggagaat ggcccagagt ttaagattga ggtctctatt
    12601 ctcaaagatg tggcaactgt catgattgat acgaccgggt ctagcctctt taaacgtggt
    12661 tatcgtaccg aaaaaggtgg cgctcctatc aaggaaaata tggcagcagc cattttacaa
    12721 ctttctaact ggtatccaga caagcctttg attgatccga cctgtggttc ggggactttc
    12781 tgtattgagg cagttatgat tgctagaaag atggcgccag gtcttcgtcg ctcttttgca
    12841 tttgaggaat ggaactggat cagcgatcgc ttgattcaag aagtgcgcac agaagcggct
    12901 aaaaaagtag aacgtgagct tgagttggat atcatgggct gtgatattga tgctcgcatg
    12961 gtggaaattg ctaaggccaa tgctcaggca gctggtgttg caggagacat tacttttaag
    13021 cagatgcgcg tgcaggattt acgttccgat aaaatcaatg gagtaatcat ttccaatccg
    13081 ccttatggtg aacgtttgtc agatgatgca ggggtgacca agctctatgc tgagatgggg
    13141 caagtatttg caccgctgaa aacttggagc aaatttatcc tgactagtga tgaagctttt
    13201 gaaagcaagt atggtagcca agcagataag aagcgtaagt tatacaacgg aaccttgaaa
    13261 gtggatctat atcaatattt tggtcagcgt gtcaaacggc aagaggtaaa atagaaaggg
    13321 atactcatga gtaaaaaaag acgaaatcgt cataaaaaag aaggtcaaga accgcaattt
    13381 gattttgatg aagcaaaaga gctaacagtt ggtcaagcta ttcgtaaaaa tgaagaagtg
    13441 gaagcaggag tcttgcctga ggattccatt ttggacaagt atgttaagca acacagagat
    13501 gaaattgagg cggataagtt tgcgactcgt caatacaaaa aagaggagtt cgttgaaact
    13561 cagagtctgg atgatttaat tcaagagatg cgtgaggctg tagagaagtc agaagcttct
    13621 tcggaggaag ttccatcttc tgaagacatc ttactaccct tgcctctgga cgatgaggag
    13681 caaggcttgg atcctctatt gctagatgat gaaaatccaa cagaaatgac tgaagaagtg
    13741 gaagaggagc aaaacctttc tcgtctggat caagaggact cagaaaagaa aagtaaaaaa
    13801 ggctttattt tgaccgtttt ggcgcttgta tcagtaatta tttgtgtcag tgcttattat
    13861 gtctaccgtc aagtggctcg ttcgaccaag gaaattgaaa cttctcaatc aactacagcc
    13921 aatcaatcag atgtggatga ttttaataca ctttatgacg ccttttacac agatagcaat
    13981 aaaacggctt tgaaaaatag ccagtttgat aaactgagtc aactcaaaac cttgcttgat
    14041 aaactggaag gtagtcgtga acatacgctt gccaaatcta aatatgatag tctagcaacg
    14101 caaatcaagg ctattcaaga tgtcaatgca caatttgaaa aaccagctat tgtggatggt
    14161 gtgttggata ccaatgccaa agccaaatcg gatgctaaat ttacggatat taaaactgga
    14221 aatacggagc ttgataaagt gctagataag gctatcagtc ttggtaagag ccagcaaaca
    14281 agtacttcta gctcaagttc aagtcaaact agcagctcaa gctctagtca agcaagttca
    14341 aatacgacta gtgagccaaa accaagtagt tcaaatgaga ctagaagtag tcgcagtgaa
    14401 gtcaatatgg gtctctcgag tgcaggggtt gctgttcaaa gaagtgccag tcgtgttgcc
    14461 tataatcagt ctgctattga tgatagtaat aactctgcct gggattttgc ggatggtgtc
    14521 ttggaacaaa ttctagcgac ttcacgttca cgtggctata tcactggaga ccaatatatc
    14581 cttgaacgtg tcaatatcgt taacggcaat ggttattaca acctctataa gccagatgga
    14641 acctatctct ttacccttaa ctgtaagaca ggctactttg tcggaaatgg cgctggtcat
    14701 gcggatgact tggactacta agcagtcgtt acaaaattct ttcttttcaa aagtaaaaat
    14761 gataaaataa aacaaatgaa acaagaggag tgtcaaatga caaaagctaa ctttggtgtc
    14821 gtaggtatgg ccgtaatggg tcgtaacctt gcccttaata ttgaatcacg tggttacaca
    14881 gttgctatct acaaccgtag taaagaaaaa acggaagatg tgattgcttg ccatcctgaa
    14941 aagaactttg taccaagcta tgacgttgaa agttttgtaa actcaatcga aaaacctcgt
    15001 cgtatcatgc tgatggttca agctggacct ggtacagatg ctactatcca agcccttctt
    15061 ccacaccttg acaagggtga tatcttgatt gacggtggaa atactttcta caaagatacc
    15121 atccgtcgta atgaagaatt ggcaaactca ggtatcaact ttatcggtac tggagtttct
    15181 ggtggtgaaa aaggtgccct tgaaggtcct tctatcatgc ctggtggaca aaaagaggcc
    15241 tacgaattgg ttgcggatgt tcttgaagaa atctcagcta aagcaccaga agatggcaag
    15301 ccatgtgtga cttacatcgg tcctgatgga gctggtcact atgtgaaaat ggttcacaat
    15361 ggtattgagt acggtgatat gcaattgatc gcagaaagct atgacttgat gcaacacttg
    15421 ctaggccttt ctgcagagga tatggctgaa atctttactg agtggaacaa gggtgaatta
    15481 gacagctact tgatcgaaat cacagctgat atcttgagcc gtaaagacga tgaaggccaa
    15541 gatggaccaa tcgtagacta catccttgat gctgcaggta acaagggaac tggtaaatgg
    15601 acgagccaat catctcttga ccttggtgta ccattgtcac tgattactga gtcagtgttt
    15661 gcacgctaca tttcaactta caaggaagaa cgtgtacatg ctagcaaggt gcttccaaaa
    15721 ccagctgcct tcaactttga aggagacaag gctgaattga ttgaaaaaat ccgtcaagcc
    15781 ctttacttct caaaaatcat ttcatacgca caaggatttg ctcaattgcg tgtagcctct
    15841 aaagaaaaca actggaactt gccatttgca gatatcgcat ctatctggcg tgatggctgt
    15901 atcatccgtt ctcgtttctt gcaaaagatt acagatgctt acaaccgcga tgcagatctt
    15961 gccaaccttc ttttggacga gtacttcttg gatgttactg ctaagtatca acaagcagtg
    16021 cgtgatatcg tagctcttgc ggttcaagct ggtgtgccag tgccaacttt ctcagcagct
    16081 attacttact ttgatagcta ccgttcagct gaccttccag ctaacttgat ccaagcacaa
    16141 cgtgactact ttggtgctca cacttaccaa cgtaaagaca aagaaggaac cttccactac
    16201 tcttggtatg acgaaaaata agtaggtcag ccatggggaa acggatttta ttacttgaga
    16261 aagaacgaaa tctagctcat tttttaagtt tggaactcca gaaagagcag tatcgggttg
    16321 atctggtaga ggaggggcaa aaagccctct ccatggctct tcagacagac tatgatttga
    16381 tgttattgaa cgttaatctg ggagatatga tggctcagga ttttgcagaa aaattgagtc
    16441 gaactaaacc tgcctcagtc atcatgattt tagatcattg ggaagacttg caagaagagc
    16501 tggaagttgt tcagcgtttt gcagtttcat acatttataa gccagtcctt atcgaaaatc
    16561 tggtagcgcg tatttcggcg atcttccgag gtcgggactt cattgatcaa cactgcagtc
    16621 tgatgaaagt tccaaggacc taccgcaatc ttaggataga tgttgaacat cacacggttt
    16681 atcgtggtga agagatgatt gctctgaccc gccgtgagta tgaccttttg gcgacactta
    16741 tgggaagcaa gaaagtattg actcgtgagc aattgttgga aagtgtttgg aagtatgaaa
    16801 gtgcgaccga gacaaatatc gtagatgtct atatccgcta tctacggagc aagcttgatg
    16861 ttaaaggcca aaaaagctac attaaaaccg tgcgtggtgt tggatatacc atgcaagaat
    16921 agataagcag ttgcagttgt gtaactgctt ttttgaggag tttttatata ttgacatgca
    16981 gtcgggtctt tgctacaatc gttttaggag gatatataga tgaaactttt gaaaaaaatg
    17041 atgcaagttc tactagcagt ctttttcttt ggtttgctag ctacaaatac ggtatttgcg
    17101 aataccacag gtggccgatt tgttgataag gataatagaa aatattatgt aaaagatgat
    17161 cataaagcaa tctattggca taaaatagac ggtaaaactt actattttgg tgatattgga
    17221 gagatggttg tcggttggca atacttagaa attcctggaa caggttatcg tgataattta
    17281 ttcgataacc aaccagttaa tgaaattggc cttcaggaga agtggtacta ttttggacaa
    17341 gatggtgctt tgctagaaca aacagataaa caagtactag aggcaaaaac gtctgaaaat
    17401 acaggaaaag tatacggtga acaatatcct ctatctgctg aaaagagaac ttattatttt
    17461 gataataatt atgctgtaaa gacaggctgg atttatgaag acggcaattg gtattattta
    17521 aataagctag gaaattttgg cgatgattct tacaatccac taccaattag tgaagttgct
    17581 aagggttgga ctcaagattt tcatgttact attgacattg atagaagcaa acctgctcca
    17641 tggtactacc tagacccaga aactggcatt atgcgaacag gatggcaata tctaggtaat
    17701 aactggtact acctccgttc atcaggagca atggccactg gctggtatca ggaaggtacc
    17761 acttggtatt atttagacca gccaaatggc gatatgaaaa caggttggca aaaccttggg
    17821 aacaaatggt actatctccg ttcatcagga gctatggcaa ctggttggta tcaagatggt
    17881 tcaacttggt actacctaaa tgcaggtaat ggagacatga agacaggttg gttccaggtc
    17941 aatggcaact ggtactatgc ttatagctca ggtgctttgg cagtgaatac gaccgtagat
    18001 ggctattctg tcaactataa tggcgaatgg gttcggtaat gacagggcgc ttataattat
    18061 attagaacac tcgcttaatc aaagaagtga ctttgttgta cttgacctga cgattgggga
    18121 gattaaaagc atgtgaaatc tacacatgct ttttcgttag ttatgagtgt tgaacttgac
    18181 taaccattga caaaagataa gagcaattaa aataagatac aaaaatatca atgctaactg
    18241 caccgaaacg cccgatgcta tggatagggc taatagggag agcagggacg gggcgagaat
    18301 gtccactgtg ctcagagcag agcccaccgt ccccatcttg tcactgggga tataggcaaa
    18361 gacagctgct tgtaggcgag ggctgagaat gccgataatc gtagaactga tgaaactggt
    18421 catgaaaatt acgatatagg cttgacaaag gatactagtt attagagcca atagggaaat
    18481 ctcacagaaa accaagaggt gcgtgaaacg gatattttta aatagattac tgctggtcat
    18541 attgccaagg atagctccac aagacatgat gatggagagc agggcgagga gttgcccaat
    18601 gctcagttgt gctagtgtct gttggatgaa gcggagggca atcagccgag gggacacatc
    18661 caagatggca atcatactgg tcgtcagaaa cagtagtatg acggtatctt ttaacttcag
    18721 tagcacagcc agcgactgtt taagatgttg aaaatatttc ttaaaactca gtgctgtatg
    18781 tgacatttca atcctttttt caacctcata caaggtatgt cgaataacat acaggcccaa
    18841 aaaggcaatg acaaaagtca gagtgttgat aagggaaata gtttgaatac ttataacatt
    18901 gataaggaat gcgccagcca gattggcgac aatgcggaca accctcatca gagactgcct
    18961 gaaccccatg gcatcatgca ggtcgtcctt aattacactg atgtagaggg cgttcatcat
    19021 gtaggcagac aggtagctca aggtgtcaga gatgaggttg atgatgacaa tcataatgac
    19081 tgaaactaat gaaaagggcg acaagacgag aaatactgtc aaaatagcgt agagcaggat
    19141 tttgattttg gcaatacaga gtgcgtgttt gactctattt tcttgaaaat ctcctagaat
    19201 cccgagaaag agttgcgata gtaggggaac catctctgaa atggaaatca gtaaaatcgc
    19261 tagcggagcg aaattgtact gagccacata attgataatg gcgaggtaga aaatactgtc
    19321 gccgaatgat gaaaaacagc tgtttagcag caactgtcta tatatgttgt ttgtccaaaa
    19381 taatttcata catttctcct tatgtctgca catcgaatgg gaatttatta tttaatagac
    19441 accaatatac ccccatgctt cctattccga agtcaaacaa atctgcttta ccactatctc
    19501 cttgaaacat cagtaaaccg tgatcatctc gttcagaaca tgctaaaatt acctgttgga
    19561 ttttttcatc agtaatttgt tttgattgta gacagtggtt tgtagtaagc tagttattcc
    19621 gtggcaatat cctgtcatca tttttagatg atggttaaaa acaaattctt gatatttact
    19681 aataatatct ttgtttccgt cacaatcgta catacaaaga tataagatta ttccggaaat
    19741 tcctttgcac caagaaagtt gtaaatttcc taaattttca gtattagaag taactttttc
    19801 taataatttt tttaattcag tatggaatgt atggagatca ttatagaaca tagaaggttc
    19861 taagacttta gaataggcaa ataaagcata tgcaattcca caatatccat gagcaaagct
    19921 atagtctaaa atgctttctt tggctgtatc tctttgtagg aaataatgat aaatttcccc
    19981 atatactatt gtggatgaaa gttttaagag tattgtcatt ggtaacttga tagtatttta
    20041 ttaatgataa taggacacca gattttccca atgcaaagtc tatttcctct agagtatcat
    20101 aattctctat taatttctta gcggtgacgt ttgctaattg tagatagtat tgatttttac
    20161 tgatagaaaa taaatgtagg agtaactata gatagcctgc accaccaaat agcagtgagt
    20221 attgatattc atatgtgtgt gacgttctaa ttgtcactgc cttcttgatg atagagagta
    20281 ttttagaatc cagttctggg tggtacaatt tatttagagg aaacagtagt ccagctattc
    20341 cgtgttggaa tgataaatta cttacgaaat ttccaaattc tgttgaagaa gtgatccttc
    20401 cttcagaatt tacagtttta tctagtaaaa atcgtagaac actattacat tctgttttgt
    20461 aatcatattt atgttcctct atttttttaa ttttgactaa attatttgtt tgacttaaat
    20521 ttagtagaca ttgtaaccaa aatagttgct catctgtgag ctgaccttga gtatgtgata
    20581 gttctagtaa ttgaatagga tcctttagtt agattcaatc aatctataac acaacaacat
    20641 aataatactt ttaggataac ttgtcaaata
//
LOCUS       DAVBNN010000035        19723 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBNN010000035 DAVBNN010000000
VERSION     DAVBNN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19723
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.035"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ847_001343"
     CDS             complement(181..1359)
                     /locus_tag="VQ847_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3050679.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ847_001344"
     CDS             1639..2901
                     /locus_tag="VQ847_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3050680.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ847_001345"
     CDS             2904..3800
                     /locus_tag="VQ847_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3050681.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ847_001346"
     CDS             3815..4132
                     /locus_tag="VQ847_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3050682.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ847_001347"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ847_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ847_001348"
     CDS             4475..5077
                     /locus_tag="VQ847_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3050683.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ847_001349"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ847_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ847_001350"
     CDS             5624..6394
                     /locus_tag="VQ847_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3050684.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ847_001351"
     CDS             complement(6672..6959)
                     /locus_tag="VQ847_001351"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3050685.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ847_001352"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ847_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7748)
                     /locus_tag="VQ847_001353"
     CDS             complement(7545..7748)
                     /locus_tag="VQ847_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3050686.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7779..8387)
                     /locus_tag="VQ847_001354"
     CDS             complement(7779..8387)
                     /locus_tag="VQ847_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3050687.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8426..8596)
                     /locus_tag="VQ847_001355"
     CDS             complement(8426..8596)
                     /locus_tag="VQ847_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3050688.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ847_001356"
     CDS             complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ847_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3050689.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9258..9422)
                     /locus_tag="VQ847_001357"
     CDS             complement(9258..9422)
                     /locus_tag="VQ847_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3050690.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9865..11346
                     /locus_tag="VQ847_001358"
     CDS             9865..11346
                     /locus_tag="VQ847_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3050691.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11708..12703
                     /locus_tag="VQ847_001359"
     CDS             11708..12703
                     /locus_tag="VQ847_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3050692.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12830..14140
                     /locus_tag="VQ847_001360"
     CDS             12830..14140
                     /locus_tag="VQ847_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3050693.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14236..15138
                     /locus_tag="VQ847_001361"
     CDS             14236..15138
                     /locus_tag="VQ847_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3050694.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15140..15985
                     /locus_tag="VQ847_001362"
     CDS             15140..15985
                     /locus_tag="VQ847_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3050695.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            15995..17314
                     /locus_tag="VQ847_001363"
     CDS             15995..17314
                     /locus_tag="VQ847_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3050696.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17524..17596)
                     /locus_tag="VQ847_001364"
     tRNA            complement(17524..17596)
                     /locus_tag="VQ847_001364"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17561..17563),aa:Lys,seq:ctt)
     gene            complement(17861..19132)
                     /locus_tag="VQ847_001365"
     CDS             complement(17861..19132)
                     /locus_tag="VQ847_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3050697.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19402..19641
                     /locus_tag="VQ847_001366"
     CDS             19402..19641
                     /locus_tag="VQ847_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050698.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
BASE COUNT         6215 a         3054 c         3852 g         6602 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataattcc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgggag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttggc atcttcggcg
     7621 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
     7681 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
     7741 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
     7801 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
     7861 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
     7921 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
     7981 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
     8041 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     8101 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     8161 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     8221 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     8281 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     8341 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     8401 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     8461 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     8521 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     8581 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     8641 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     8701 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     8761 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     8821 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     8881 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     8941 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     9001 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     9061 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     9121 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     9181 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     9241 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     9301 gctgcaccta taatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     9361 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     9421 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     9481 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     9541 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     9601 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     9661 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     9721 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     9781 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     9841 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     9901 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     9961 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
    10021 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
    10081 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
    10141 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
    10201 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
    10261 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
    10321 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
    10381 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
    10441 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
    10501 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
    10561 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
    10621 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
    10681 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
    10741 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
    10801 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
    10861 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
    10921 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
    10981 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
    11041 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
    11101 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
    11161 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
    11221 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
    11281 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
    11341 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
    11401 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
    11461 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
    11521 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
    11581 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
    11641 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
    11701 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
    11761 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
    11821 tttaaggaaa gttcaaaggg ctataaaaac attggactat atccctgata attatgctcg
    11881 aggtatgaaa aagaatagaa cagaaactat cgctttgatt attccgagca tatggcatcc
    11941 atttttttcg gagtttgcct atcatgttga gaaagagtta ttaaaatata attataaatt
    12001 atttatttgt aacgctgata gcgattcaca aaatgaaatc gaatatatcg aaatgttgaa
    12061 acaaaataaa gtggatggaa ttattggtat tacatattct gatattgaca aatatatttt
    12121 atctgattta ccgtttgtaa gtatagatag acatttttcg gaaaatgtat gctatgttac
    12181 ttcagcaaat tacaaaggag gacaaactgc agcagaggaa ctggttagaa gggataataa
    12241 gcaccttgct tttattggtt caattaatat gtatgagaat gagactatac tcagaagtaa
    12301 aggattcaga gaaaaagcta aggaattagg agtagatgtc tataattttg aaatgaaaga
    12361 acctttaata aatcctgaag atcagataag aatttttttg caatctcata aagaaattga
    12421 tggtatattt acaataaatg atatgatggc tctgagagtt attagtgtta tgaaagaact
    12481 ggggaaaata gcacctgatg attaccagat aattgggttt gatggtttaa aaacttctgt
    12541 cgatcaatct tatctagtgt ctacaatagt tcaagatatt ggtatgatgg caaaagaatc
    12601 tgttgcaatg atactgaaaa tgattaagcg agaagagatt ctagaaaaac gaatcgtaat
    12661 tcccacatat ttttggggag ataaaacaac aaaaaaaatt taaaaagcgc ttgacaatta
    12721 atgaaagcgc tgttataata taatcaacaa atgaaacgtt tcaaaaatag gctagaagct
    12781 tgtttaaaaa ataaataaaa aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg
    12841 tacaatgtta tctgttgttg cggggctatc gttagctata cttgcaggtt gtagtggagg
    12901 aactaactca aaacaagcga gttcttcaaa tgatattaaa gtctgggtac aattctctga
    12961 cgaaacaaat gaaggaaaag cttggcaaaa agttgttgat aactttaatc aatcaggaaa
    13021 aagtaagtac aaggttgtaa ctgagtatat tcctcgtagt ggtagtggtg gaggatatga
    13081 agacaaggtt aatgctgcta ttacgactaa tagtcttcca gatgttatta cccttgatgg
    13141 accaaatacg gcagcttatg caaaatctaa agtaattact ccgctagatg attatctaaa
    13201 agataataat atggatgatg ttttggacag tattaaacaa cagggaactt ataatgggaa
    13261 attctatgca tttggatttt ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt
    13321 caaagaggcc ggaattgcgg aatcagagct tccaacgcta gaaaagccat ggacatggga
    13381 cgaatttaat acgattgcta aaaaattgaa agatcattat aacaaaccag caattgattt
    13441 tcgtattaat tcaaacgatg aaatgttgcc atatgcttat atgccgttga tttggtcaaa
    13501 taatggttct gtcgtaaacg aagatggaac aaaggcagaa ggatacttca actccaaaga
    13561 gagtgtagaa gcagttcaat tcattcaaaa tcttgtaaaa gaaggctata caactgttag
    13621 tccagtcgaa aaaggttttg aaacaggaga gtatccaatg cttttgagtg gttcttggac
    13681 gattgctgac atgaatacaa actacaaaga tattgatttt ggtatccttc cttacccagt
    13741 atctagtaag acgaaaaaat tagtatcccc ttcaggtagt tggcaattag ctgtgacgac
    13801 aaaatctgat aaaaaagagg ccgcatctga atttgttaaa tttgctacaa atacagaatc
    13861 aagtgaaatt attagcttgg ggaattcggt ccttccaatt cgtaaatcta caattgaaaa
    13921 tatcaaagat aaagtatccg aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc
    13981 tcatgctcgc ccagttgttg tagcatatcc tcaggtttct cgagcttttc aacaagcaat
    14041 gcaagatatt agctattatg aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac
    14101 aaaagaaatg caaactgcta ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga
    14161 aggaaaatgt ttggaactac cttccccttt cttgttaata gcctagtttg atatatatga
    14221 ttaaaggaga tggatatgag taaagaaact gttgtggata caaaaagacg tgaaaaaata
    14281 aaggataaca tattaggtta tagtttttta gctccagctt taattttatt aggtatcttt
    14341 ttagtaattc cagttggaat ggtcatttat tacgctttta cagattatta tttgttgaca
    14401 ccagatgaaa gaaaatttgt tggacttgaa aattttattc gattaacaaa agatccgatt
    14461 ttcttaaaga gcttcttgaa tactttgaaa tttgttgttt ggattattcc agttcaattg
    14521 ggagcggcct taggaatggc tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt
    14581 aaagtggctt tttttgctcc agttgtcatg tccttggtag ttatttctat tctttggctt
    14641 tatcttttaa atccaaatag tggcttattg aatgctattt taaataaggt aggtattgct
    14701 tctcaacctt tcttgactag tcctaaacaa gctatgtatg caattgtttt tgtttctgct
    14761 tggcagggtg caggttatca gatgctttta tttttaggag gaatgcagaa tattccacaa
    14821 gatgtctatg aagctgctga attagatgga ttctcaaaat gggctcagtt tcgttatatc
    14881 acgatgcccc tactaaaacc aacagccctg tttgtattgt taacaacttt aatttctgct
    14941 tttaagctga ttgtacaacc aatggttatg acgcaaggtg ggccattaaa ctcaacaatt
    15001 actatggtgt actatattta tcaacaaggt tttactgatc gtcttgtagg atattctagc
    15061 tcaatcgctt tagtatttac aacgttaatt ggtatgatta acttagtaca acgtcgcgtt
    15121 ctgaaggagg atgactaaga tgaaacgatt taaaccaaca acaatcttag aatatattct
    15181 gttaacttta ttggcaggac tcttcctttt tcctatggtt tggatggtag tttcagctat
    15241 gaagccagaa gcggatgttt ataaaaattt gactagttgg caagccttct taccaagttt
    15301 aaatcccgct gattggttta aaccttatca ggaagtattt gagcgcttta gtatttttac
    15361 atatctaggg aacagcattt tttatgctgg aacgtttgct attggttcta ttattgtcaa
    15421 tgcactggcc ggtttcgctt ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg
    15481 tttcttactt gctttactta ttattccagt ggaaactgtg ttaattccac aatttaccat
    15541 tatcaattcc ttaggtttgg tcaataatcg tcttgcagtt attattccag gattggcgag
    15601 tgtatttaat atttacttat ttaggaattt ctttattgca attccagaag agattcttga
    15661 gtctgcaaag atggacggag caagtatcgt tagaattttc tttagaatta tgcttccaat
    15721 gtctaaacct gcagttgcta cagttggtgt tttatcattt atttcaagct ggaatgatta
    15781 tatctggcca ttgatggttt tgacagattc ttctaaattt tcaatgcagg ttgcaattac
    15841 aactattaat acaactcaac cagtttatat caatcaggta atggctgtat taactatttc
    15901 aacgattccg ttgattttgg tctatgtagt cgctcagaaa tatattgttc aaggtctggg
    15961 tggttccgga actggaataa aataggatat acttatgata aataaaacat ttacagtaga
    16021 aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat ataagcctga
    16081 agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg tctattttcg
    16141 tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg ggcctatgca
    16201 ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag tggcacttgc
    16261 tcctgatcaa gattatgacc gaaatggttg tttctcaggc tctgccattg tcaaggatga
    16321 tcgcctctgg ctcatgtaca ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca
    16381 aaatatggca ttttcagatg acgggattca ctttgaaaag atttcccaaa atccagttgc
    16441 aactggatca gacttgccag atgagttgat tgctgctgat ttccgtgatc caaaactctt
    16501 tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaagaata atgtgggctg
    16561 tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca tctttttaaa
    16621 aggggtagaa caccaaggct ttatgtggga atgcccagat tacttcgagt tagatgggaa
    16681 agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat atcataacat
    16741 caactcatcg cttttgttca cgggtaaggt agattgggga gaaaaatgtt ttatcccaga
    16801 atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat tgttggacga
    16861 tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc ttccaaccca
    16921 tgaccaagaa cacaagtggg catgtgccat gactttacct agaattctaa gattggaaga
    16981 tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa tagataaaga
    17041 ttgtcattac cacttaggaa atgatacaga ttatcttgaa tttggttatg acagtaatgt
    17101 gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg aagaagaaca
    17161 ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg ttctagataa
    17221 aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa cttattactt
    17281 aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct cctaaagaaa
    17341 aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat ataagcttag
    17401 tttatggtat ttgtaaaatt ggtgttggat tatgatttaa actagttttc taaagaattt
    17461 gaaaaaaatt ttatttaagc aaaaaaagcc ctatattata agacttttcc tgttgtattt
    17521 atatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca
    17581 gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt
    17641 gaacccgcgc aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga
    17701 cggcctacat gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa
    17761 cacttaagtg tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttta
    17821 aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt
    17881 cgatagcttc ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga
    17941 aatagtgatg attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat
    18001 agttgtgtgg atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc
    18061 catcacgtag gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct
    18121 tatccatagc tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat
    18181 tggcaatgag aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca
    18241 cggtatgaat ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca
    18301 agcgacgagc gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac
    18361 tggcatccac atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac
    18421 cgtctccatc cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta
    18481 aggtgatgtg gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg
    18541 agttaaaggc agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct
    18601 catctagttc tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg
    18661 cctctttgac gtcttggtta gacagaggtt ccaactcgaa aatttgaaca cggctacgaa
    18721 tggcaggagt gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc
    18781 cactttccaa gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt
    18841 ctagcaatag gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct
    18901 ttttactatc aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg
    18961 cagaggcaat actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc
    19021 ggttggcttc caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga
    19081 tgacctggtc gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc
    19141 tttctaacgt ggatttgagt agaatgactc atctactata tcttactatg tccattctag
    19201 cctattagtt gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt
    19261 ttactattta atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct
    19321 caaaatagga tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg
    19381 aatgtcattg tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca
    19441 agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt
    19501 atttcaggga aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg
    19561 tacgaaaaca ttaaatctaa acttgatttt gcttaccaag aagttcattc taataatggg
    19621 ttgaaaaaat atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcctccttgt
    19681 aataactgtt gaaaatcctg atttcgaaga cttgagagtt aat
//
LOCUS       DAVBNN010000036        19393 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBNN010000036 DAVBNN010000000
VERSION     DAVBNN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.036"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(10..1071)
                     /gene="dinB"
                     /locus_tag="VQ847_001367"
     CDS             complement(10..1071)
                     /gene="dinB"
                     /locus_tag="VQ847_001367"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3050699.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            1466..3790
                     /gene="pflB"
                     /locus_tag="VQ847_001368"
     CDS             1466..3790
                     /gene="pflB"
                     /locus_tag="VQ847_001368"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3050700.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(4162..4380)
                     /locus_tag="VQ847_001369"
     CDS             complement(4162..4380)
                     /locus_tag="VQ847_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050701.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(4476..4714)
                     /locus_tag="VQ847_001370"
                     /pseudo
     CDS             complement(4476..4714)
                     /locus_tag="VQ847_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4707..4991)
                     /locus_tag="VQ847_001371"
     CDS             complement(4707..4991)
                     /locus_tag="VQ847_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050702.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(5603..5773)
                     /locus_tag="VQ847_001372"
     CDS             complement(5603..5773)
                     /locus_tag="VQ847_001372"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050703.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEEAG"
     gene            complement(6596..7819)
                     /locus_tag="VQ847_001373"
     CDS             complement(6596..7819)
                     /locus_tag="VQ847_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3050704.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            7988..9310
                     /locus_tag="VQ847_001374"
     CDS             7988..9310
                     /locus_tag="VQ847_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3050705.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            9312..11198
                     /locus_tag="VQ847_001375"
     CDS             9312..11198
                     /locus_tag="VQ847_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3050706.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            11366..11710
                     /locus_tag="VQ847_001376"
     CDS             11366..11710
                     /locus_tag="VQ847_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3050707.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            11720..13132
                     /gene="lacG"
                     /locus_tag="VQ847_001377"
     CDS             11720..13132
                     /gene="lacG"
                     /locus_tag="VQ847_001377"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3050708.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            13202..14881
                     /locus_tag="VQ847_001378"
     CDS             13202..14881
                     /locus_tag="VQ847_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3050709.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(15007..16446)
                     /locus_tag="VQ847_001379"
     CDS             complement(15007..16446)
                     /locus_tag="VQ847_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3050710.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(16450..17799)
                     /gene="trkA"
                     /locus_tag="VQ847_001380"
     CDS             complement(16450..17799)
                     /gene="trkA"
                     /locus_tag="VQ847_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3050711.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            17987..18835
                     /locus_tag="VQ847_001381"
     CDS             17987..18835
                     /locus_tag="VQ847_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3050712.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            18850..>19393
                     /locus_tag="VQ847_001382"
     CDS             18850..>19393
                     /locus_tag="VQ847_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3050713.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKK"
BASE COUNT         5911 a         3292 c         3951 g         6239 t
ORIGIN      
        1 cattgagctt taaaatccag tcagggtaat ccccaatagg cggacacctc tttctttctc
       61 gcttaattct tcatagagtt gcagggctat ttggcttatc tgactagcat cttgtgtttt
      121 ttgagcaaga ctttttcgtt tggtaagagt tgaaaagtcc tcgtagcgga ttttcaaaat
      181 gacaattttt ccagcttttt cttgttgatg tagattgaga gcgacttttt ctgatagaag
      241 agtcagctct tttttgatat cttcctcagc acggagaatc ttcccgtagg ttttctcctt
      301 gccgattgat ttacggatgc gattggattt gactggagag ttgtgaatgc cacgagcctt
      361 tcgatacaga tcatagccta gtctaccaaa acggtctatt agggtcacct caggaacttc
      421 aagtaaatca gcaccagtaa aaacgcccat ttgatgaaga cgttctactg tcttttttcc
      481 tactccatga aatttggaaa tatccatttg tttgagaaaa ttctcagcct gttcaggtag
      541 aatcactgtc aaaccatgag gtttttgata atcactcgcc attttagcta agaacttgtt
      601 gtaggaaata ccggcagaag cagttagatg gagttcttgc cagatatctt tttgaatgag
      661 gcgagcaatt ttgaccgctg acttgatacc gagtttattt tctgtcacat ccaaataggc
      721 ttcgtcaatg ctcatgggtt caatcaaatc tgtatagcgc ttaaaaatag ctcgaatctg
      781 gagtcccaca gctttgtatt tctcataatt tcctgagata aagacggcct ggggacaacg
      841 ttcataagct tccttggaac tcatggcaga atggacacca aaagctcgag cctcatagct
      901 acaggtagaa acgactcccc gtccacctgt ttgccgaggg tcgcttccaa taatgacagg
      961 ttttcctctg agtttaggat tatccttgat ttccaccgca gcaaaaaagg catccatgtc
     1021 aatatggatg atttttcttg acaaatcatt taacaaagga aaaatcaaca tgcctagcac
     1081 ctttttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttccatctgc aacctcaaaa
     1141 cagtattttg agctgacttc gtcagttcta tttacaacct caaagcagtg ctttgagcag
     1201 cctgcggcta gcttcctagt ttgcttttcg atttccattg agtgttactg cttattttct
     1261 tttattatac ccttttttct gaaaaaaaga aaaaaggact ttattttttt caaaaatata
     1321 atacagtttg aaataaaata tagactgttt tagaaaagaa agtgtaaaaa tagggatttt
     1381 gcacttgttg aaatcgatta ctttatggta tacttgtctt atgaatgtaa cagatgactg
     1441 ttactagaaa aaagaggaca ttaatatggt tgttaagacg gttgttgaag cacaagatat
     1501 ttttgacaaa gcttgggaag gcttcaaagg cgtagattgg aaagaaaaag caagtgtatc
     1561 acgctttgta caagctaact acacacctta tgatggagac gaaagcttcc ttgcaggacc
     1621 aacagagcgt tcacttcaca tcaagaaaat tgtagaagaa actaaagcac actacgaaga
     1681 aactcgtttc ccaatggaca ctcgtccaac atctatcgct gatatccctg ctggatttat
     1741 cgacaaagaa aatgaagtta tctttggtat ccaaaatgat gaactcttca aattgaactt
     1801 catgccaaaa ggtggtatcc gtatggctga aactacttta aaagaaaatg gatacgaacc
     1861 agacccagct gttcacgaaa tcttcactaa atatgtaaca acagttaacg acggtatttt
     1921 ccgtgcctac acttcaaata ttcgtcgcgc tcgtcatgca cacactgtaa ctggtcttcc
     1981 agatgcatac tcacgcggac gtatcatcgg tgtttacgca cgtcttgctc tttacggtgc
     2041 agactacttg atgcaagaaa aagtaaacga ctggaatgca atcaaagaaa tcgatgaaga
     2101 aacaatccgt cttcgtgaag aagtaaacct tcaataccaa gcattgcaac aagttgttcg
     2161 cctgggtgac ctttacgggg ttgatgttcg caaaccagcg atgaacgtga aagaagcaat
     2221 ccaatgggtt aacattgctt tcatggctgt ctgccgtgtg attaacggtg ctgctacatc
     2281 tctaggtcgt gtaccaatcg tattggacat ctttgcagaa cgtgaccttg ctcgtggtac
     2341 atttactgaa tcagaaatcc aagaattcgt tgatgatttc gttatgaaac ttcgtacagt
     2401 taaatttgct cgtacaaaag cttatgacca attgtactca ggtgacccaa cctttatcac
     2461 aacttctatg gctggtatgg gtaacgacgg tcgtcaccgt gttactaaga tggactaccg
     2521 tttcttgaac actcttgaca acatcggtaa ctcaccagaa ccaaacttga cagttctttg
     2581 gactgacaaa ttgccataca acttccgtcg ctactgtatg cacatgagcc acaaacactc
     2641 ttctatccaa tacgaaggtg taacaacaat ggctaaagac ggatatggtg aaatgagctg
     2701 tatctcatgc tgtgtgtctc cacttgatcc agaaaatgaa gaacaacgcc acaacatcca
     2761 gtacttcggt gctcgtgtaa acgttcttaa agcccttctt actggtttga atggtggtta
     2821 cgacgatgtt cacaaagact acaaagtatt tgacatcgat cctattcgtg acgaagttct
     2881 tgaattcgaa tcagttaaag cgaactttga aaaatctctt gactggttga ctgacactta
     2941 cgtagatgcc ttgaacatca tccactacat gactgatagg tacaactacg aagctgttca
     3001 aatggccttc ttgccaacta aacaacgtgc caacatggga ttcggtatct gtggatttgc
     3061 taacactgtt gatacattgt cagctatcaa atacgctaca gttaaaccaa tccgtgacga
     3121 agatggctac atctacgatt acgaaacaat cggtgactac ccacgctggg gtgaagatga
     3181 cccacgttca aacgaattgg cagaatggtt gatcgaagct tacacaactc gtctacgtag
     3241 ccacaaacta tacaaagacg cagaagctac agtatcactt ttgacaatca catctaacgt
     3301 tgcttactct aaacaaactg gtaactcacc agttcacaaa ggtgtatacc tcaacgaaga
     3361 tggttctgtg aacttgtcta aacttgaatt cttctcacca ggtgctaacc catctaacaa
     3421 agctaaaggt ggttggttgc aaaacttgaa ctcactttct agccttgact ttagttatgc
     3481 agctgacggt atctcattga ctacacaagt atcacctcgc gctcttggta agactcgtga
     3541 tgaacaagtt gataacttgg taacaatcct tgatggttac ttcgaaaacg gtggacaaca
     3601 cgttaacttg aacgttatgg acttgaacga tgtttacgaa aaaatcatgt caggcgaaga
     3661 cgttatcgta cgtatctctg gatactgtgt aaacactaaa tacctcactc cagaacaaaa
     3721 aactgaattg acacaacgtg tcttccacga agttctttca atggatgacg ccttggatgc
     3781 attgagctaa tcaagttctt gaataataaa aaggaaccct cggtcaaacg actgagggtt
     3841 ttgtgcttgg gatagtatga gcaattcctt cggcgcaata tgcaatgttt ttgggaagga
     3901 acagtggacc gaatctgaaa tataatagat tgaaactaga atagtacacc tttacttcta
     3961 aaacattctt agaaatcgat ttgactgtcc tgatcgattt gtcctattct tatttcattt
     4021 tactatagtc cgctgaaacg gctcaaacag tgctagaaat tgactggaat tctctaagtg
     4081 atttgttccg attttatttc atttcatttc atcataaaaa taagacgact ggctaattga
     4141 caatcatctt gtttgatact gttaataaaa ttcgcgaagt ttatcttgat tttctttaaa
     4201 aaatttttct aaccaatcca taccataagc ataactaaaa ccttctaata gaacagagag
     4261 gtcaatagta tcaaatccca tgtcttttaa atatttaaag gtatcgaatg gtgaatgaaa
     4321 gtttttgtat ttaataattg caccaatatc ttgcaaatcc tgctctctga tactcatcat
     4381 cttcattcct aacacatact caatagggac tactaaaacg gtcagattct caaatgagta
     4441 caaggattcg cataaactta agggaggttg tttgttcata tttgctttgc aacatgattg
     4501 ttgagccata actcttcgtg gatgttaaga ttaaactgtt ttcctacacg agcaataatt
     4561 tcattgattt tctgattttg gtcataaaaa gcatcaacat cttgtgtggc acgtaaacca
     4621 tgatattcta agacataacc ataattgtta aagtcagatt ttcctgaatt aatttcttat
     4681 ttagggcttg gaagaccggt ttcattttat ccatgtttgt atttctccat caatttttga
     4741 acattggtta acttagcagg tttatttaat gaaatcacat atttatgagt tggagtatgc
     4801 tcttgaaagg catacttcaa gctaattttt tgaaaacggg ttagttcttt ggagtctagc
     4861 aacttttcta catcttggtt tgttaaataa gaatagtctt caaaaataac ttttcgcaaa
     4921 tagcgaaacc aatggcttgc gttgaattgt gattgtttgg atgcctgtat catataatcg
     4981 taccaatcca ttgtcttcct cctataaaat ttagtttata ttattgtagt ttatattcaa
     5041 aaatgtagtt tttcttaatt agctcgtatc tataggatga tactgaaaat cttcttgttg
     5101 ctttaaatca caatcgaaaa attctgtttt tcatcttaga aaagaatgtt tagaaatgta
     5161 aaatgaacct tttttcttat ccgaaaacct tactaaagta tataatttag gcagtcaatt
     5221 ctgtatgata atgtttgtac tatcgtcgag tttttgcttg attgcctaac gagataaatt
     5281 ttagaagagt tttcggtgtg atttgacaag tttctgactg gaaggatagt tacactagta
     5341 ttgtttatta aaatgagcag atagagaaaa tttggaatct atttgcttat tatcaatcgt
     5401 ttttttagct tatttgtctt agattggtat agaactgatt tatggattaa tcctcttgta
     5461 tcttatcctg ttcctaaata tgttggtaga aaaatgaagc agttgttacg agtgtctgta
     5521 ttggaaaaaa ttttatctat acaattcttt aaatgatatt aaggctagga atgccaaaac
     5581 actgacatat ttcgtttaaa gcctatccag cctcttcaat tgtatttgta gaaatgctat
     5641 cagtaatata ttcgcgaaca ctatgattta caacagtgtg gtcgtacatc tttgtaactt
     5701 tattatacaa caaccattta caggtgtaaa gttgagcagt gtctttagta aatttaggga
     5761 cttgttttgt catagttttg atacctgtat tcgttgtttc atgagcattt aatgttaata
     5821 cccctgttta tatatccatt tcaacaatta gaatgatatt tttccgagga tgaacttata
     5881 tattgtgact ttttagagtt atgatgcctc ttgatttgac tatcgctatc aatttcatcc
     5941 acttttacag tttcatggtt ttatgaaccg aaacatctag gtacaggttt tagcatcaat
     6001 tgattgtttt tgagccatat gaagttgaaa cgtggagatg cttttcttgt gataacgccc
     6061 tattcaaaga ggcataaccg tttttggaga gagttcagta ctatgtggcg ctaaataata
     6121 tatgtaaaat agtatggtgt agagatatta aacaagattt aactaatact tttcgaaaat
     6181 ctcttcaaac cacgtcagcg tcgccttacc gtatagatgt tactgacttc gtcagttcta
     6241 tctacaacct caaaacagtg ttttgagcag cctgcagcta gcttcctagt ttgctctttg
     6301 attttcattg agtataagga gaattgtaaa aacaaaaatg gggatttcat ataaagttta
     6361 ttctaggagt atgtatcttg aataaaaatt gttatttaag ttctgggggt tatgatgaat
     6421 gtttttataa taataaaatg cagctagaag aaaagttatt ttaatataaa tcactcaaca
     6481 tagagagaag gcggtttcct atatggaagt cgtcttgttt tcatattgtc taaatacgag
     6541 atatttacta caggttatag ttgatttaaa caggtctata gatttctaat atatattaag
     6601 gtgaaataat atcttgtaat acattgctat gctctatgaa aaaagcaacg atagctaatg
     6661 cacaagctcc tatacttcca cgatgtttgt tgtaaggtaa aatttcaatt tctatattac
     6721 gagtaaaggg aacgaagtgg agctggtctt ggattttatc cctgacttca tgagtgaaag
     6781 gttgataatt aagcaattga ctgttgatat agattttatc agcaggattg atgaggagaa
     6841 gatttgcaat agaagtggct aataaattga ctcctttatc aatttgttga cgtaaagcgg
     6901 agtcgcctaa attataagcc gttaaaaggg tgtctaaatg aatgtctttt tcagtcttta
     6961 caaggctttt tagtacagtt agttgggaat ttttaaataa taattgggcg tgtttgatta
     7021 accaagcatc cgaaatatat gtttgtaaac aacctttttt tccgcattca caatattgcc
     7081 cattcaattc gacaatggtg tgtccaattt ctccgatata aggattttta gaggctccta
     7141 ttttttcttt tgtgaaaaag gaagtgtaaa tacctaatcc agcgtgtagg aaaataaagt
     7201 tatcgggggt attgtgtgga ttaaaaaggt attgtcctat agccatacaa tcgatattat
     7261 tttttacaat aaaaggaaaa ttgaatcttt taattacatt taataaatta aaagattccc
     7321 atatggggtt gtttgtaatg atacttccgg agtctttgtt ataatgtcca ggtattgata
     7381 agccaaatcc aagtaatttt gtttccaaag ggacgtactc tatagctgtt tttatcatat
     7441 tggtaatggt ggaattgatt tctgaaatag gataatcttc attcaaaatt tctgtctcga
     7501 aaagagtttt cccttgtaag tcacatagac tgagaaagat acctaggacg tttatttcaa
     7561 tacctccaac aacatacgga atattatctg tgatagaaat agtttttcta cgtcttccag
     7621 atccggaaaa ctcgctaaat tcatcaccag tttcgtatat gagggactgt tcgcttagct
     7681 cttttatgat gttagtcgtt gttgctggag taagtcctgt ttcattaaca atatctgtac
     7741 gggatgttgc tggatttcga tatagaaact ccagtatagt ggctctattt tgtaaaaagg
     7801 ctgattgttt tgtaatcatt tgtttcctcc tttggtttat tttatattaa acataagaaa
     7861 aaatcaatta aaattattat tctatacaaa gaaaaaaata ttgtaaaaac aacaaaaaaa
     7921 tatattgaca acgctttctg ttagtggtat atttaattta taaaaaataa aaaaaggagt
     7981 tccggtgatg aacaatattt tagcgttttt agaaacaaaa gtcgctccgt ttggtgaaaa
     8041 agttggcaac caacggcatt tgaaagctat tcgtgaagga tttatgatgg caatgccttt
     8101 gattttagtc ggatctttat ttcttattct aatcagttgg cctcaagagg attttacaaa
     8161 ttggctgaat agtgttggat tgctaagtat cttgacaact atgaatcagt caacagtagc
     8221 gattatctcc ttggtcgctt gtttcggtat tgcctacagg ttgtcggaag gatatggtac
     8281 agatggtccg tcggcaggga tcatagcctt atccagtttt gtattgatgg cacctcgttt
     8341 ttcgagtatg gtttatgata aaaatgggga gcaggtcaag cagttatttg gcggcgcaat
     8401 accattttct agcctgaatg catcttcttt gtttatggcg attactattg gattggttac
     8461 agcagagatt tatcgtatgt ttatccagcg cggaattacg ataaaaatgc caagtggtgt
     8521 cccagatgtg gtaagtaaat cattttcagc tcttttacct ggctttacta cttttgtttt
     8581 gtgggctctg gtcttaaaag gtcttgaagc ggcaggagtt gcaggaggtc tcaacggact
     8641 cctaggtgga attgttggaa caccgcttaa gttaattgca ggaacgcttc caggtatgat
     8701 tctatgtgtt attgtaaact cattcttttg gttctgtgga gttaatgggg gacaagtttt
     8761 aaatgctttt gtagatccag tttggttaca atttactata gaaaaccaag aagctgtggc
     8821 tgcaggacaa acactccaac acattattac attaccgttt aaagatttat ttgtatttat
     8881 tggtggcggt ggagcgacta ttggtcttgc gatttgtctc ttcctattta gtaagagtcg
     8941 tgcgaataaa acattaggta agctagctat tataccgtct atttttaata tcaatacagc
     9001 tattctattt acgtttccaa cagttttaaa tccgattatg ctgattccgt ttattgctac
     9061 tcctacaatc aatgccttga ttacctatgt atcaatggct gtaggattag taccctatac
     9121 aacaggtgta atccttccgt ggacaatgcc accgattata ggaggcttcc ttgcaacagg
     9181 ggctagttgg cgaggagctc tattacaagt tgttttgatt ttggtttctg tagcaattta
     9241 ttatccattc ttcaaaattg cagataaacg caatcttgaa aaagaaaaag ctactgttgg
     9301 agggaaataa gatggttatc agagtatttg atcaacagaa aaatacttat tctagctttg
     9361 ccttagagga attaagttac tatatgaatc gggtctttaa gactaacata gagcttgtcg
     9421 aggagaagga agcggatatt tttgtaggat tagtcaataa agaggacaga aaagaccatg
     9481 ttcttatctc attagacaag ggtaagggaa gaattgagtc taatacaatt gtaggtttac
     9541 ttattggaat ttaccgaatg tttcatgaat ttggggttgt gtatactaga ccagggcgca
     9601 gacatgactt tgttccagag ttacgatttg aagatttttt agataaacag ctatctatag
     9661 atgaaacagc cagttactat cataggggag tatgtataga gggagcggat tcatttgaaa
     9721 atatactaga tttcattgat tggctaccta agattgggat gaacagtttt ttcatccagt
     9781 ttgaaaatcc ttactctttt ttgaaacgtt ggtatgaaca tgaatttaat ccatatctaa
     9841 ataaagaaca attttcaaat gaattagtac aagaattgag tgataggttg gataaagaat
     9901 tgcaaaaaag aggtcttatt catcatcgtg ttggtcatgg atggacaggt gaagttttag
     9961 gttactcttc aaaatttggc tgggaatcag gtcttagtat ttcagaggag aagaaaccct
    10021 atgtcgctga aataaacggg aaacgagaat tgtttaatac ggctccgatt ttaaccagcc
    10081 tggatttttc aaatccagat gtagctgata agatggtaga aattatcaag gattatgcca
    10141 agaaaagacc tgatgttaac tacttacatg tatggttgtc ggatgctcgt aataatattt
    10201 gtgaatgcga aaactgtaga caagaattgg tttcggatca gtatattcgt attctcaatc
    10261 aattggatag ggctttaacg agtgagggat tagatacaaa gatttgtttt ctgctttacc
    10321 atgagttgct atgggcgcct cagaaagaaa aattagataa tcctgaacgc tttaccatga
    10381 tgtttgcacc gattacaaga acatttgaaa tgagttatgc agatgtagat tttgacaatt
    10441 ccatacctac gcctaaacct tatctgcgta ataaaattat acttccgaat tctcttgagg
    10501 aaaatttatc ttatcttttt gagtggcaaa aaacatttaa aggagatagt ttcgtatatg
    10561 actatccttt agggcgtgct cattatggcg atttaggcta tatgaaaatt agtcaaacca
    10621 tttacagaga tgtatcttat ctttctaacc tacatttgaa cggttacatt tcgtgtcaag
    10681 aattacgtgc cggattccct cataattttc ctaattatgt tatgggggaa atgctctgga
    10741 agaagacaag aagttatgaa gaattgattg aagaatactt ttctgctttg tatgggtcaa
    10801 attggcagtc tgttgttgaa tatttagaaa aattatccag ttattcctca tgtgattatt
    10861 ttaatgcaat tggcagtcgt caaaatgatg ttttagcgaa tcattattat atagcttaca
    10921 atctagctga taattttttg ccaattattg aggaaaatat ttctaagtta ttaaatagtc
    10981 aaaaggatga atggaaacag ctcagttatc atcgtgaata tgttgttaag atggcgaagg
    11041 ctttatatct tcaagcaacc ggaaaaacaa ggcaagctca agatgaatgg agaaatgtgt
    11101 tgaattatat ccgtgggcac gaactgctat tccaatctaa tttggatgtt tatcgtgtaa
    11161 ttgaagtagc aaaaaattac gctggtttcc acttataaat cataagtata gaaaatgaac
    11221 caaggtattc agagaagatt gatcctaaat attatgaaat ttaaggattt ttaagatatt
    11281 tagggtcgac tttctattta tatcgtagcg aagtcatttt aataatgatg tgtaaaagat
    11341 ggatcaagat tgaggaggaa gaaagatgaa atcaaaagaa gaaataaata tgcttggttt
    11401 tacaattgtc gcttacgcag gagatgcaag gtcagatttg atggatgctt tggcgtttgc
    11461 gagagatgga tattttgaac aggcaagaga attggttgag tctgcaaacg actcaatagt
    11521 gtctgcccat cgagaacaga ctaatttatt agcggaggag gcatctggag ataattttga
    11581 agtgagtttt atcatgattc atggtcaaga taccttgatg acaacgatgc tattgtatga
    11641 tcaggtcaag ttttttattg atgaatatga acgaattcga aagattgaag aacatattgg
    11701 tttgcaatga ggattagtca tggaaaattt acaggttaaa gccttaccga aggagttttt
    11761 attaggagct gctaccgctg cttatcaagt agagggtgca actagggtag atggcaaagg
    11821 aacaaatatg tgggatgttt atttgcaaga aaacagtccg tttttaccag atccggctag
    11881 tgatttttat tatcgttacg aagaggatat agctttggcg gcagaacatg gtttgcaggc
    11941 tttgcgttta tctatttctt gggttcgtat atttcctgat atagatgggg agcctaatat
    12001 attagctgtt cgttattacc atagagtctt tcagtcttgc ttaaaacata atgtgattcc
    12061 gtttgtttct ttacatcatt ttgattcgcc tcagaaaatg ttagaaacag gggattggtt
    12121 gaatagagag aatattgatc gtttcatacg atatgctcgc ttttgtttcc aagaatttac
    12181 agaagtcaag cattggttta caatcaatga actgatgtct cttgctgcag gtcaatatat
    12241 aggaggtcag tttcctccaa atcatcattt tcaattatct gaagcaattc aagcgaatca
    12301 taatatgttg ttggcgcatg ctcttgcagt ccgcgaattt catcaattag ggattgaggg
    12361 aaagataggt tgtattcatg ctttaaagcc aggctatcct attgatgggc aaaaagaaaa
    12421 tattttggca gctaaacggt atgatgttta taataataaa tttctattag atggaacttt
    12481 tttgggctac tacagtgagg acacgctttt tcacttgaat caaatattgg aagctaataa
    12541 ttctagcttt attattgaag atggtgattt agaaattatg aagagagctg cagctcttaa
    12601 tacgatgttt gggatgaatt attatcgttc agaatttatt cgtgaataca aaggtgaaaa
    12661 tagacaagaa tttaattcaa caggaataaa aggacagtct tcttttaaat taaatgctct
    12721 aggtgaattt gtaaaaaaac ctggtattcc gacaacagat tgggattgga atatttatcc
    12781 tcaagggtta tttgatatgt tgcttcgtat caaagaagaa tatcctcaac atccggtcat
    12841 ttatttaact gaaaatggta cagcccttaa agaagttaag ccagagggcg agaatgatat
    12901 tattgatgac agtaagagaa tccgttatat tgagcaacat ttacacaaag ttttagaggc
    12961 tcgagataga ggagtcaata ttcaaggcta ttttatatgg tctttgcaag atcaattttc
    13021 ttgggcgaat ggctacaata agcgatatgg tcttttcttt gttgattatg aaacacagaa
    13081 gagatatatt aagaaaagtg ctctttgggt aaaagggcta aaacggaatt aaggttagcg
    13141 atttgactga tgtttaatat attttaacta tgagcttaaa ttttttacag gaggagtttt
    13201 tatggataag ttagtcgctg ccattgaaaa gcaacaaggg aaatttgaaa aaatttctac
    13261 taataattat atgatggcta ttaaagatgg atttattgct actatgcctt taattatgtt
    13321 ttcaagcttt ttgatgatta ttattatgat tcctaaaaat ttcggagtag agttaccgag
    13381 tccagctatt gcctggatga ggaaagtgta tatgctaacc atgggagttt tgggtattat
    13441 tgtttcaggg acagttgcaa agtcattggc tggaaatgtt aatagaaaaa tgcctcctgg
    13501 aaaggtaata aatgatactt ctgcaatgtt ggcggccata tgtggctatc ttgtattaac
    13561 tgtaacgctt gtagttgatg agaaaacggg atctacaagt ttgtcgacaa actatttagg
    13621 atctcaagga ttgataactt cgtttgtcag tgcctttatt actgtaaatg tttaccgatt
    13681 ctgtattaag cgagacatta ctattcattt acctaaggaa gttcctgggg ctatatcaca
    13741 agcttttaga gatatttttc ctttttcttt tgttttactt attagtggtt tgttagatat
    13801 tgtatctcgt tttagtttag atgttccttt tgcccaagta tttcaacaac tattgactcc
    13861 tatttttaag ggggcagaat catatcctgc tatgatgttg atttggttta tgtgtgcttt
    13921 gctttggttt gttggaattc atggaccatc tattgtctta cctgctgtta cagctttaca
    13981 actgagcaat atggaagaga atgctcaact tcttgcaaat gggcagttcc cttatcattc
    14041 tttaacacct aatttcggga attatatcgc tgctattgga ggaacggggg ctacctttgt
    14101 tgtaccattt attttgattt tctttatgcg gtctaaacaa ttaaaatcgg taggtaaagc
    14161 tacaattact cctgttttat ttgcggtaaa tgaacctctt ctatttggta tgcctgttat
    14221 tttgaatccc tatctttttg tacctttttt gatgactcca ccagtgaatg tatttctagg
    14281 aaaggtattt attgatttct ttggaatgaa tggattttat atccagttac cttgggcctt
    14341 tcctggtccc ttgggattgt taattggaac gaattttcaa cttatctcct ttgtattttt
    14401 atctttgatg ttagttgtcg acatattgat ttatttgcca ttctgtagag cgtatgatag
    14461 acagttactg gtgaaagaag atattgcaag ctcaaatgat attattttag aggaggatac
    14521 aagtgaaata atgccttgtg agatagatgt aataaaaagt aaggagttga aagtactggt
    14581 tctttgtgca gggtctggaa caagtgcgca attagccaat gcaattaacg agggcgctca
    14641 attagcagaa gttagagtga ttgcgaattc aggagcgtac ggagctcatt atgatattat
    14701 gggtgtttat gatttaatta ttctggcccc acaagttcgg agttattata gagagatgaa
    14761 ggtggatgca gaaagattag gtattcagat agttgctacc agaggaatgg aatatattca
    14821 tttaacaaag agtccaagta aagccttaca atttgtattg gagcattacc aagctgtgta
    14881 gtaagttttt ccatctttta tttgagtaaa gattttgctt acagataggc ttggatttaa
    14941 aaacgttccc ccttttttaa tataagaatc cctctttcac aattgtaaaa agagggattt
    15001 tgtattttat ctcttagacc aagttctctt cataaagaga aggaggattg ggtaaatctc
    15061 caagcgccct gcaatcattg caaaggatag gagaattttt gagatgggac taaagattga
    15121 gaaactagaa gtggttccta gaataggccc gatattattg aaacagctaa agacagcgct
    15181 ggtcacgacc agaaaatcat tgctatctag gctgacaata aagataagcg ctagcaaaat
    15241 catagcatag atgacaaagt acttgagaat cttatgctgg gtatctttgt caatcaccgt
    15301 tttattaaca tggagggtca aaacacggtg gggcgatagg attgacaaaa tttggttttt
    15361 ggcaattttt gaaaggatga ggcctcgaat aatcttgagt ccacctgcag ttgatccagc
    15421 agagccaccg attgccatga ggaaaaggag gataaactgg gagaagaggg gccagttggt
    15481 aatatctcca tatccaaaac cagttgttgt aatgatgttg gaaacctgga agaaggtcat
    15541 ttcaaagctc tttgaaaacc ctgggtagag gtagagggtg ttgaggctaa tcaagcctgt
    15601 agaaaccagt acaatgacca agtaagcccg aagttcttcg tcaccaaaga aggccttgat
    15661 gcgacggagc atgaggtagt agtagaggtt gaaatttacc ccaaaaacca gaactccgat
    15721 actgaccaga taggtaatca gtgagctgcc atagtgggca attccgtcgt tatagacggt
    15781 aaagcctcca gttcccgctg tccccatagc aatgacaaaa ctatcgtaga gaggcatacc
    15841 agctagataa tagatgatga caaagaggga gaagagagct agataaagga gatagagaat
    15901 ctgggcagtg ttttttagtt tggatacaac cttgccaaaa acaggacctg gaacctcagc
    15961 cttcatcacc tctaggtggc tatttttggc attgtccata atagcaagtg caaaaacaag
    16021 cactcccatc cctccaatca agtgggtaaa acttcgccag aagaggaggg aacggctgag
    16081 aaccgaaatg tcgttcaaaa tacttgctcc agtagttgta aacccagaac taatttcaaa
    16141 aaaggcatca ataacgctag ggatttgccc agaaaagaca aaggggagac caccaaagaa
    16201 agaccaaagg atccaacaga gggcaacgat caagactccc tccttggcat aaatccgttg
    16261 attttttggc ttctgtaaac tccctgaacc gcctaacaat acgagaatcc ctatggtcga
    16321 aaagagggct gtaaagactt ggctcgattc acggtaatag acagcgatag ccacaggaac
    16381 caagaggaga acagcttcaa tcaaaagtaa ctttgaaagg aggtaacgaa tcatactttt
    16441 attcatttct tacctcgcaa tcaagtcata aatcttggtg atgtttggca acaaggttgt
    16501 tactaggagc ttgtctccaa cttccaacat atcctcccca gttgggaaaa tagtcttgcc
    16561 ctttcgaata atggctgcaa taagaacccc ttttttcaat ttcagttgag aaagaggttt
    16621 ggcagtcatt ttattggctt ccttgatatg gaattgcagg gtttcaattt ggccattggc
    16681 tagatggtgc atggcttgaa ggtctgaata ctgggcatta actcgaccac gaataaagtg
    16741 cataatcgta tctacagcga tgcttttagg tgtgatgata cttgaaaaat caggcgcatt
    16801 gataatctcg aggagactgg tacgattgac cttagtaata tttttctgta cacctaccct
    16861 gtcaaggaac atagatgtaa tcagattttc ctcatcgaca cctgttagag tcgcaacggc
    16921 atcatagtgt tgagcacttt cttccagcag gatatctttt gcggttccat ctccttgaac
    16981 gatgtagaga tttgggaatt tctcgctaaa gaagctggcg atttcaggat tgatttcaat
    17041 gacttttgta tcgatacgac tatctttgag aataccaagt agataatagg caattctacc
    17101 tgccccaacg atgagaaggc tcttcacggc gcgtgattta aaataattat ggaagagtat
    17161 catatcgaca cggttaccag tgacaaagat tctatcttta tcctgtacag tcatgtcacc
    17221 gcttggaatg ataatttgat gatccctctc tatcgcacag acaatgacat taccaaattt
    17281 tttacgaaaa tcagaaatgg gcatttggca aagaccgctg gtggacttga cgacaaattc
    17341 catgaggcta acgcgtccac cagcaaagcg ttcgacagac agggcgttgg ggaagtcaat
    17401 gatattcgcg atagcgcggg cagccaagag ctcaggatta acgataagag aaaaaccgag
    17461 aatattcttt tccttgaaat aagagttaga atattcaggg ttccgcaccc gaacgatagt
    17521 ttctttagct cccattttct tggctagaac tgctgcaatc atgttgactt catcgtgctc
    17581 agtcagggcg ataaagatat cacaatcttg gacgctggct tgctcaagaa tggcaaaatc
    17641 ggccccgtta ccaaggatac caatgatatc aaagcgattg acaatatgat tgagaacagc
    17701 ttcgtcttgc tcaatcagca aaacatcatg cttttctgca accaaggagc gacagagggc
    17761 aaaaccaact tttccccctc cgacaaggat aattttcata ataaaaccta ctttttcatg
    17821 atgtaactat catacccttt ttcaagaaaa aatgcaccta ctagctaata acaagagctt
    17881 ttagtgaaaa ttcgctataa ggtaaaacta taccctaacc aattgaaata gctattagcg
    17941 actttctctg aaatatggta tgataaagga tatacaagga gataaaatga ataataattt
    18001 actggtatta caatcagact ttggtctggt tgatggtgcg gtatcggcta tgattggagt
    18061 ggctttagaa gagtctccaa ccttaaaaat ccatcacttg acgcacgata tcacgcctta
    18121 taatattttt gaggggagct atcgtctctt tcagacggtg gattactggc ctgagggaac
    18181 gacgtttgta tcggttgtcg atccaggtgt cggttcgaaa cgtaagagtg tagttgccaa
    18241 gactgcaaaa aatcaataca ttgtcacgcc agataatggg acgctttcct ttatcaagaa
    18301 acacgttggc attgtagcca ttcgtgagat ttctgaggtg gccaataggc gtcaaaacac
    18361 agagcattct tataccttcc acggtcgtga tgtctatgcc tatactggtg ctaaactggc
    18421 cagtggtcac attacttttg aggaagtagg gccagagctc agtgtggaac agattgtaga
    18481 gcttccagtc gtagcgacca tcatagaaga tcatctggtg aagggagcca ttgatattct
    18541 ggatgtgcgt ttcggttcgc tttggacctc tatcacacgg gaagaatttt acaagctgga
    18601 accagaattt ggtgatcgtt ttgaagtgac catctatcat gctgatatgc tggtctatca
    18661 aaatcaggtt gtctatggca aatcatttgc agatgtgaga attgggcaac ccatccttta
    18721 catcaactct ctctatcgtt taggtttggc tatcaaccaa ggttcctttg ccaaggccta
    18781 taatgtaggt gtcggttcat cttggaccat tgaaataaag aaaatagaag gataaaatag
    18841 gagaatagta tggaaatcaa atttacaatt aaacaagttg ttgctgtcgg aattggcgct
    18901 gccctctttg tcgtcatcgg gatgatcaac attccaaccc ctgttccaaa tacaagcatc
    18961 cagcttcagt atgcggtaca agcgctactt tctattattt ttggaccgat tatcggtttg
    19021 cttgtcgggt tgattggtca tgcaatcaag gactctcttg ctggttatgg tctatggtgg
    19081 acttggatta tcgctagcgg actttttggt ctagttgtgg gactttttag aaagtacgtt
    19141 cgagtgatca atggtgtttt tgactggaaa gatattctta tttttaacct cattcaacta
    19201 cttgcaaatg cccttgtttg gggtgtcttg gcaccacttg gagatgttgt gatttatcaa
    19261 gaagcggcag aaaaagtatt tgcacaaggg attgttgcgg gaattgccaa tggtgtatct
    19321 gtagctattg caggaactct tctcttactt gcctatgcag gaacccaaac tcgtgcagga
    19381 agtttgaaaa agg
//
LOCUS       DAVBNN010000037        19119 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBNN010000037 DAVBNN010000000
VERSION     DAVBNN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.037"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(119..751)
                     /locus_tag="VQ847_001383"
     CDS             complement(119..751)
                     /locus_tag="VQ847_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3050714.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ847_001384"
     CDS             complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ847_001384"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3050715.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ847_001385"
     CDS             complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ847_001385"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3050716.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2567..3139
                     /locus_tag="VQ847_001386"
     CDS             2567..3139
                     /locus_tag="VQ847_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3050717.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3191..3511)
                     /locus_tag="VQ847_001387"
     CDS             complement(3191..3511)
                     /locus_tag="VQ847_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3050718.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            3936..4220
                     /locus_tag="VQ847_001388"
     CDS             3936..4220
                     /locus_tag="VQ847_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3050719.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            4275..6383
                     /locus_tag="VQ847_001389"
     CDS             4275..6383
                     /locus_tag="VQ847_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3050720.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            6380..7021
                     /locus_tag="VQ847_001390"
     CDS             6380..7021
                     /locus_tag="VQ847_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050721.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            7228..8034
                     /locus_tag="VQ847_001391"
     CDS             7228..8034
                     /locus_tag="VQ847_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3050722.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            8000..8470
                     /locus_tag="VQ847_001392"
     CDS             8000..8470
                     /locus_tag="VQ847_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3050723.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(8760..9080)
                     /locus_tag="VQ847_001393"
     CDS             complement(8760..9080)
                     /locus_tag="VQ847_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3050724.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            9844..10224
                     /locus_tag="VQ847_001394"
     CDS             9844..10224
                     /locus_tag="VQ847_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3050725.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            10598..11656
                     /locus_tag="VQ847_001395"
     CDS             10598..11656
                     /locus_tag="VQ847_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050726.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            11971..12947
                     /locus_tag="VQ847_001396"
                     /pseudo
     CDS             11971..12947
                     /locus_tag="VQ847_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13324..13698
                     /locus_tag="VQ847_001397"
     CDS             13324..13698
                     /locus_tag="VQ847_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3050727.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            13906..14808
                     /locus_tag="VQ847_001398"
     CDS             13906..14808
                     /locus_tag="VQ847_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050728.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSP
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            14864..15217
                     /locus_tag="VQ847_001399"
     CDS             14864..15217
                     /locus_tag="VQ847_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3050729.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            15214..15942
                     /locus_tag="VQ847_001400"
     CDS             15214..15942
                     /locus_tag="VQ847_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050730.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            17074..17313
                     /locus_tag="VQ847_001401"
     CDS             17074..17313
                     /locus_tag="VQ847_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050731.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYAGQTKPAIQAGVFILEDFRNILCTMM"
     gene            17863..>19119
                     /locus_tag="VQ847_001402"
     CDS             17863..>19119
                     /locus_tag="VQ847_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3050732.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATGWLQN"
BASE COUNT         6183 a         2932 c         3858 g         6146 t
ORIGIN      
        1 atctacaacc ttaaaacagt gttttgagca gcccgcagct agtttcctag tttgctcttt
       61 gattttcatt gagtattact tcattttctt ctgaaataga gttgtcgccc agtctatgct
      121 attgaaaata cgccaaaact tctaagggtt tgtgagcgat ataatcaggt tgatagttta
      181 gtagatctgc ttgctctcca aatccccaag tgacggccaa tttctgaata cctgtttctc
      241 gagctcccag catatcaaac ttggtatctc cgatgatgat ggcttgttct ggtgctagtt
      301 gatgtgtctg taaggcttgg tgaatgacat ctgccttatg gggtgcttca gggctagaac
      361 cataaatacc atcaaagaaa tgatggattt ccaagttttt ggccatgtct tgagcagtag
      421 atgtattctt tgtcgtggtg atgtagagtg gataactgct cgataactcc tcaagcaagt
      481 ctataatctg aggaaagagt tgagcttcat agatgccttt tgccttatag taagaacgat
      541 atatctgcat ggcttcagaa atttggtctt tggacaggca ggtcgcaaaa ctactttcga
      601 gaggtggtcc cataaaacca cgaatagttt tggcatcagg gctaggcacc cccagctctt
      661 taaaagtata ggtaaaggca ttgtgaatcc cgatagaact atcaacgagg gttccatcca
      721 aatcgaaaaa aatcgctgtg atagaggtca tggtttctcc tatttgataa gcttattctc
      781 cgaaaatctc tttttggagg cgacgaccag taggggtggt agcgagtcca ccttcagctg
      841 tttcacgaaa ggcagttggc atgcttgctc ctacttggta catggcatcg atcacttcat
      901 ccacagggat tttagattcg atacctgcca aggccatgtc tgctgcgatg aaagcaaagc
      961 tagctcccat ggcattacgt ttgacacagg gaacttcgac caaacctgca acagggtcac
     1021 agatgaggcc tagcatattt ttaatgacaa aggcaatagc ttgactggcc tgataaggtg
     1081 ttccacctgc agccagagtc aaggcggcag cactcatagc agaggctgaa ccaacttcag
     1141 cttgacaccc accctcagca cctgagatgg aggcattgtt tgcgatgact agtccaaagg
     1201 caccagcagc aaagaggaaa tccaattgtt gctcgtggct gaggtctaat ttttcaatag
     1261 cagcagtgag aacggaaggg agacaaccgg cacttcctgc ggtaggagta gcgcagacca
     1321 agcccatttt agcattgtgt tcattgactg cgatagcatt tcgggcagca gagagaatcg
     1381 tgtaatctga taaagttttt tcgtttttga tgtagtgatc caatttggca gcatctccac
     1441 ctgtcaggcc actacgagat ttattttcat tgaggccaag ttggacagag gctttcataa
     1501 cttccagatt gcgttccatg agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa
     1561 actctgttgt aatcatgagt tctgcgacat ttccttgaaa gtccagatct gcttgctcga
     1621 ccaattcttt gatagaataa aacatgcttc ctcctattta aagaaattga cattgtggag
     1681 atgagggatt tttcgaattt cttcgatagc ctcatcacag ttgcgactgt caacttcgat
     1741 aatcataatg gctttttcac cagctttttc acgagtgaca ttcatctggg cgatattgat
     1801 accatagcgg gaaagcgcct ctgtaacaag ggcaatcata cctggaatat cttgatgaac
     1861 gatgatgata gtcggtgtat tcatattgag agagacggca aaaccattga gttcggttac
     1921 ctgaatattt cctccaccga tagaaatacc agtcacgctg atggtcttgt gggcattttt
     1981 aacagtaatt ttagtggtgt tagggtgagg ggcattgctg tctttctgaa tggtccagac
     2041 aatcttgata ccacgcttgt gggcaatttc cagactattt ggaatttcag gatcatctgt
     2101 atccattcct aaaatacctg caacaagggc taggtctgtt ccgtgaccac gataggtctt
     2161 ggcaaatgag ttaaaaagtt ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga
     2221 gacaatcttc ccaatacgaa cagcaccagc ggtatggcta ctagatgggc caatcataac
     2281 tggtccgatg atatcaaaga cagattgaaa acgaagtgat ttcatcagtt tccccttata
     2341 aaaattctta tctctattat atcaaagaat gaggggcttg gctttaattg tggatgaaaa
     2401 cctttctaat acctcaaata gcataaaaat agtatctttt atgacaaaaa acaccttatt
     2461 tagggaaata aaaaataatt ttgtaatatt tctacataaa agtgtcaaga aacggtaata
     2521 tttaaagggt atgatagaac tatagaaaga aggagaattt tcgaatatga aatcaataac
     2581 taaaaagatt aaagcaactc ttgcaggagt agctgccttg tttgcagtat tttctccatc
     2641 atttgtatct gctcaagaat catcaactta cactgttaaa gaaggtgata cactttcaga
     2701 aatcgctgaa actcacaaca caacagttga aaaattggca gaaaacaacc acattgataa
     2761 cattcatttg atttatgttg atcaagagtt ggttatcgat ggccctgtag cgcctgttgc
     2821 aacaccagcg ccagctactt atgcggcacc agccgctcaa gatgaaactg tttcagctcc
     2881 agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag ccaaagaatg
     2941 gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt atatcggacg
     3001 ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc aagaacgtgt
     3061 agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa acttctggct
     3121 taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc gaggaaatcc
     3181 ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt ttgagatgag
     3241 acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg ataagtttag
     3301 aatcgtctgt acaaatccca atacggacat agcagatagc cagcctatcg tagcttttct
     3361 tattcttggc gtcctctagt aaagtgtagc agatttgctt acacatgttt ttatcttgat
     3421 tgtatagata gagtgtggaa aggttgagca ggattgctat ttgcaagtca tataaatgtt
     3481 gatagttttt atagacttct aagcgttgca agattttctc ggattattga caaataaacg
     3541 gacattctga tagacgattg ccctagcggc ttagtgtaaa ctttacaaat ttggcttgta
     3601 atttttttat aaaattcact tcagttactt gacagttatt atattttcac ttattatata
     3661 gataaaagga tgagatggga gtttaaaaat ttgaaagcgc tatccatatt gtttattgga
     3721 ctgattcttg agtaatagtt agagtgtgct taatactact ctggttgttc aaggacctga
     3781 tacagaagcg caccattctc tcggttaaga gtaagttcgt tgttaaaaaa tgaaatgaga
     3841 tagaaggaag gtgagtccaa tggactacga tacttgttga taaattacta tagctgtttt
     3901 tacggaagag ctctcgataa taggagaaat aaatcatgag aaaattagtt aaaattggtg
     3961 ttgcatcttt aatggtatgt agtatacttg cttctacaag tgttttggca gtatgggttg
     4021 atggtggtca atggaactat ggagtaggat ggtcaggaaa ttttggttat tctgattatt
     4081 tacattctac tcgctctcat acagcaactg ttaaagatgg aaataaattc tctaaggatc
     4141 gtgcagaagc tgaggcatgg gctcgggctt caatcttcaa attcccacca acgggaatgg
     4201 aatatttcta tggattttaa ttaaaattct ccctcccctt ttggagaggg agtttcttca
     4261 cgggaggtat ctctatgaaa aaaatcagtc atctttgtat gttactcctg cttctgtgta
     4321 ccactttttt tgtttttaat gtaaactata cacgagaagt ggttcggatt caagaaatgg
     4381 gaaagactgt agattctttg gatttgtatt tgaaagatat taacgaacct gcagcgtctg
     4441 ttcttcgatt ttttgaggat gtatcaaagg agtataaagt ctccatcatc aaaacagaca
     4501 gtggtgatga ggtggtcaag tctggtgttt ttgataaaga taccttcccc taccaagagt
     4561 ttgggatttc ttctcttgat tttaccacag atggtgaagg agtctatagt aataaagaaa
     4621 tttccaataa acttggtacg attccgacct ttctaaaagc caaacctatt cagcttatga
     4681 cttttcaaac ctatatcaag gatacatctc gtagtttaaa tggtcgctat acgataactt
     4741 ctacacaaga gatggacaag gataggattg tacagaaatg gagcgatttt ttcaagatag
     4801 accaggctac cttgctagag ccgacctaca aaagtgcagt ggaagtcata aatcgagatt
     4861 tgcttttatc tgccattgtt tttgtcttgg ctattttgct tcttgtgtta gtgacagtgt
     4921 atcaaccgat gatggagatg aaaagagttg gggtacaaaa attacttggt tttcaagata
     4981 gggctgtttt agctgatgtt gtaaaaggca acctttacct cctcctaggt ggggctcttg
     5041 tgatcaatct aggcgtgttt ttcttgcttg attataagcc aaaagatttg tttcctatgc
     5101 tgtggttgtc tcattttttg ctgttgcagc tttatctctt tatcagttgg ttgacttacc
     5161 tcttaatcca aaaaatgaca atcagctctc tgctgaaagg tttttcatct ttcaaatttg
     5221 gtctactctt taattatttg atgaaaattg gaactaccat tttactgaca gtcttgctag
     5281 ttggggtagg aaaaagtttg gagcaagaaa acaaagagtt ggattaccag aaacagtgga
     5341 tcagccaagg aaattatctg accttagaaa ctttccaact caatgataac ttgtggcaag
     5401 agcagttggc aggctcaggg aaggcattgg attatttcta tcgattttat caggatttgg
     5461 tagaaaaaac gcaggcgggc tatgtgcaga gtagcagtct tcctgtaaaa aattttgtcc
     5521 aatcagaaca gattcagcaa tatcagttaa cagatacggt ggatgtttac tatgccaatc
     5581 gcaattttct aaagagcaag ggattcaagc taccagatac cggtattaaa aaagttattt
     5641 tgatgccagc aagtacgaaa ggtgaagaag ataaaaatca gctcttgggg aagttaattg
     5701 cctttcattc gatgaagtat gaagagcagc aaaaacgaac gatagaggag atggatgtcg
     5761 agattgccta ttatgaagga gattggtcat ttttcccata tagtgataag cgaaaggaaa
     5821 atctctccaa tccaattatt agcttggtca atgattctga tatgatgtgg gatgagaaag
     5881 cctccctgtc aacaactggc ttaaataatc cgattaaaat tgaaaatacg gttcaacatc
     5941 aaaaagagat tacagagtta gttgagaaat tgtcagatgg aaattattta aaattttcat
     6001 ctattcaagc cattcaacaa gagaaagtgg attcttatcg agatgctgtt cggaatttta
     6061 acctactctt tgctttgttt ggtctcctta gcatgatgat ttcctacttc ttactagtaa
     6121 taactttctt attgaagcgc agggatatca ttaccaagaa gtttatgggg tggaaactgg
     6181 tcgatcgcta ccgtcctctc ctcgttctgc tcttgctggg ctatagtttc cctcttctag
     6241 tcttgatttt ctttgcccat gcgttcttgc cacttctgct gtttgcaggc tttacatgtt
     6301 tggatatact atttgtgcta gtcttggctt ctaggatgga gaaaagaagt ctagtagagt
     6361 tattgaaagg gggcatctta tgattgagtt ggaaaatatt accaaaacca ttgggggaaa
     6421 agtgattttg gatcacttgt ctctcaggat tgatcagggg gatttggtag ctattgttgg
     6481 aaaaagtggt agtgggaagt cgaccttgtt aaatttatta ggtttgatag atggtgatta
     6541 tagtggacgg tatgagattt ttggtcagac aaatctagcg gtcaattctg ctaagtcgca
     6601 aacaataatc cgtgaacata tctcttatct gtttcaaaat tttgccctga ttgatgatga
     6661 aacggtcgag tacaatctca tgctggcgct gaaatatgtg aaattgtcta agaaagacaa
     6721 gctcaaaaag gtggaagaga ttttagagag agtaggtttg tcatctactt tgcatcaaaa
     6781 ggtttccgag ttgtctggtg gcgaacaaca acgaattgca gttgctagag ccatcttaaa
     6841 acccagccag ctgattttag ccgatgaacc aacaggttcg ctagatcctg aaaatagaga
     6901 tttggtcttg aagtttctct tagagatgaa tcgcgagggg aaaacagtca ttattgtgac
     6961 ccacgatgct tatgtagccc aacaatgtca tcggatcatt gaattgggcg aggggaaatg
     7021 agtttgttca gctctttttg actgactgaa tactcatgtt tttcagagag gaatagcata
     7081 aatacgccta gaaatgacat ttttatgtag tatttctagg tttttttgtt tcaaattgaa
     7141 aatttttcca atttaggctt gacaaaggat gaagataggt gtattattta tacaaccaaa
     7201 aagaataaac ataaaggaga ctttgttatg aataagatga agaaggtgtt gatgacgatg
     7261 tttggtttag tgatgctccc cctactattt gcttgtagca acaatcaatc ggctggaatt
     7321 gaagccatca agtccaaagg aaaattggtt gtagccctca atccagattt tgctccattt
     7381 gaataccaaa aagtggttga tgggaaaaat cagattgtgg gttcagatat cgaattagcc
     7441 aaggctatcg caacagaact aggtgtcgaa ttggaactat ctcccatgag ttttgataat
     7501 gtactggcta gtgttcaatc aggaaaagcc gaccttgcca tatcaggtgt ttctaagaca
     7561 gatgaacgga gcaaggtgtt tgacttttcc attccctact atactgcaaa aaataaactc
     7621 attgtcaaaa aatctgactt gactacttat cagtctgtaa acgacttggc gcagaaaaag
     7681 gttggagcgc agaaaggttc gattcaagag acgatggcga aagatttgct acaaaattct
     7741 tccctcgtat ctctgcctaa aaatgggaat ttaatcacag atttaaaatc aggacaagtg
     7801 gatgccgtta tctttgaaga acctgtttcc aagggatttg tggaaaataa tcctgattta
     7861 gcaatcgcag acctcaattt tgaaaaagag caagatgatt cctacgcggt agccatgaaa
     7921 aaagatagca aggaattgaa agaggcagtc gataaaacca ttcaaaagtt gaaggagtct
     7981 ggggaattag acaaactcat tgaggatgcc tttaaagcat ccattgaaaa atagaaagaa
     8041 ggaaaagaac atgagtaaag aaaaagtaat tttggcctat tctggcggtt tggacacatc
     8101 agttgctatt acctggttaa agaaagacta tgatgttgtt tcagtttgta tggatgtggg
     8161 tgaagggaaa gacttagact tcatccatga taaggctctc aaggttgggg cagtcgaatc
     8221 ttatgtcatt gatgtcaagg acgaatttgc tacagattat gtgctagtgg ctcttcagtc
     8281 acatgcctat tatgaacaaa agtacccctt ggtatctgcc ttgagccgcc ctcttatttc
     8341 taaaaaatta gttgaaatag cgcatcagac aggagcgact acaattgctc atggctgtac
     8401 cggtaagggg aatgaccaag tcgaatacca gattgcagtc gctaagaaag cgaatgaagc
     8461 taaaaagtga tggagtgatg ggttcagaat aagaggttgg tcgattggta gcctctttct
     8521 tgtcgttgaa aaagtgagat atattgactt ttgaaaaaaa tgtcataatt gagttgggat
     8581 aaacgtaaaa gtcatacttt ctcgttaaat cgttcggcga ttcatggtga catggacaca
     8641 tagtagtaaa cacactatgt ggcttggcag agctaaaaac ttctggctta acaatggctg
     8701 gtattaagaa ctaacgaaca aataatatgt aaagagtcga ggaaatccct cgactttttt
     8761 tataatttct ttggttgata atgggtctct acttcttttt tgagatgaga cagcatagaa
     8821 gtttcctcgg tcagctctag gagtgagaac cctttttgga taagtttaga atcgtctgta
     8881 caaatcccaa tacggacata gcagatagcc agcctatcgt agcttttctt attcttggcg
     8941 tcctctagta aagtgtagca gatttgctta cacatgtttt tatcttgatt gtatagatag
     9001 agtgtggaaa ggttgagcag gattgctatt cgcaagtcat ataaatgttg atagttttta
     9061 tagacttcta agcgttgcaa gattttctcg gattattgac aaataaacgg acattctgat
     9121 agacgattgc cctagcggct tagtgtaaac tttacaaatt tggcttgtaa tttttttata
     9181 aaattcactt cagatacttg acagttatta tattttcgct tatgcttatt atatagataa
     9241 aaggacggga taggagttta aaaatttgaa agcgctatcc ataataataa cgcataattt
     9301 tctccttttc gtgaaaaaag ttaacgtaat tttaaaatga gcttaataag aggtactatg
     9361 taggtagaaa ataaagatag gagaaaaagt atgaataaaa aaatattttg tattctggta
     9421 tgtattatat cattgattag tctagctata atctttccat ggggctggtc gatataatgt
     9481 aagggagctt gagttgttag tggaggataa aatgttaaga gtaatagtag ttattcaatc
     9541 tttagtaata atactgcttg ctgttgcttt attattatct cggaaaaact ttgattcgtt
     9601 aaatgttgtt cttataatga tgatcgtatc acaattgttg ttattagtat atttgataaa
     9661 atcagggaat cagtgattag ctgttatttg aattaagtaa actgttaagc ttcaagcagt
     9721 aactggtttt aaatatttaa aataagataa aggaaggaag tctaatttag gtaactaaac
     9781 aaagcctgcg atcacttgtt aggaaactat cctaaccatg cttaataaaa aaggagaaaa
     9841 taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga gatgatgtat
     9901 cttgatgggg gtggtgttgg tcgtaactgg tggaatagta gaggtagttt tgcaacagtt
     9961 ttggatgtag gtttggccat ctatagtggt ggtgcaacaa tttattctgc ttatgcgata
    10021 aaaaaagcta tctcagctaa tagaggggct attacgagaa cattacgtag tttaataatt
    10081 aaacatgtag gtagtgcagc tggccattta gtcaatactg cactaaacgt tgcactaact
    10141 gttactggat tttcactagg tggagcaatc gcatatgggg ctgattgggc tgacggtagc
    10201 ttagatggtt atatttttgc ttaaaatgaa acattttttt gcaggaattg gtgaaattca
    10261 ttttttgtta tttttattat atctaagcat gtctgctagt ccaattattg gactagtgat
    10321 tggatatact aaaataaatc taataaattc tattattata gctcttggta tgatattggc
    10381 attaattttg gtattatcaa gagtgtatag aaaatatttt tatagagacg atgatgacta
    10441 aagtttttat caataatttg ggctccttgt caactgtagt gggttgaaga aaagctaacg
    10501 tctggggaag gggttaaagc tttgctttat caaatattga cttacagagt tgctctattg
    10561 tattgatgta ttcttagtaa ataatatggt gttttgaatg aaagatgatc agaaatattt
    10621 attagcggga ctttattcgc ttctagttgc aatattttat tttccattga ttgagtccaa
    10681 ggggattttt gtaagtatat tgatggcggt tttactttta tatttaatat acttcattgg
    10741 aacagtcatt catattgtga taattaagtt tataagaaaa aaatctttta agtatttggt
    10801 tctatatcca tttacttatg atgggagctg gagatttcaa cctataaact tactctactt
    10861 tccagaaatg gtgagagatg tcattccgat taatttagtt caagaatatt gccaaggaca
    10921 accttacggg ctgttaaaaa agatgctgaa aagaattcga ttgtcacgag agatagcttt
    10981 actcctggct accattatcg tctatttttt tacgcataga attctacctc tttcagtatt
    11041 tacgttcatg ttttcttaca tattgatatt tgcacaatct tatttgggtg gtaatactgc
    11101 ttggattgga aatagaagat taataataga tgatgaattt gaaaaaatct tgctttcaaa
    11161 aagttatata aaagaaatat catctgcacg atactcggaa tacttgacat gtgaatacaa
    11221 aaaccttaca ccaatcatat tgttagctat ttttgaaaat ttacttgact cctacttgct
    11281 tcagaatcag agtgaggttg acttagatat tttttataaa gttttacctt tgctttataa
    11341 agaaaaatat actatgggat tcaattactt tgtaagttta aattatttac tatataaggt
    11401 tggatttttg ggaatcattt acgataatga agcattagga gatttgtcaa aacaatattt
    11461 aaacagaaat atttcggaat tacaagatgg ttctttcgag ggcggtatac aagatgctgt
    11521 tgcctctaaa caaatagtag ttataaatga atttatagct tgtttaaatt ccagatgcat
    11581 gccatcccaa tatgatagat ttttttataa agatagacct tatatttttt ccagaaagag
    11641 tcctattaag aggtgaaaat ttgttacatt tggattaaca agtgtcctag ggattagaaa
    11701 taactctagt atagctagat atttttgagt aactagaaat atcattaggc tacccatatg
    11761 attgccagaa aagatggctg atgaatctta tttatactgt tgcagtaggc gttgtctagg
    11821 ataaataagc tatcttgatg ggggagattg gaataatttt agtagaaaca ttaaaggatt
    11881 atgggcaagt agcacaggat taggtgatgc aatgtgctaa gttggcttgg tgttagcagt
    11941 agtattattt aacaatggaa agtagactaa atgaaaaata aacgttattt ttttgacaca
    12001 attttaatga ttttactact tataagcacg atattttgtg tcagcccagt atttataaaa
    12061 ttggacatct taggaactcc ctctcatgcc atcttaacct ttgtattggc gataccgtta
    12121 ttctatattt tgtctcaatg cttacatact ttgctattac tagtttcctc aatcttttgt
    12181 aaattaagac caatttattt ttattttata tttgtgatca ttataggagc taggaaatac
    12241 tatcgaattc tctttcacca actaatggga tttagtccag gaatagcagt gttttataag
    12301 gagagtcaaa caactaagaa tctgtttaaa ttttactact tcttgtactt tacaacacta
    12361 atttcatact attttttctt tacttttgtg tatgacaaac cgttgctttt gcctcttatt
    12421 ccattttcta ttatcatagc attagtacaa aaactttata gaattgagaa tcagcaatta
    12481 tttctgttaa aatcaaaggt actaacaata ctggaatcta agaagaattg tgagtttaat
    12541 cttcaggatt atcatgaaat ttggaaattg caatcaaaat ctgagttgcc atgcgtggct
    12601 ttatcttata tcagtttgat caagccatat ctttcagaga gcgtgcgtga acaaattgat
    12661 ttattagaag ttaagcgatt taaaaaaata aatcatccaa tatcacttta tggtatgttg
    12721 gatgttataa aattaaatct atatttacgg cattataatg aaaaaataaa tatgaatcaa
    12781 tgttaaagaa aattttagag gtaagaccag actttgtttt aatcgagcag aatattgatg
    12841 atagtttaaa tagctcgcaa ccattatctt tatctttagc tatttcagaa atccaacttt
    12901 tgcttgaagt gtatataggg atcaaacatg tttcaattag gagataaaac tagaataaca
    12961 tttgctatta taggggcaag ttgcatatta gtcagtatgt atcttatacc tctcattaac
    13021 acggataata aattttggga aatactttta tttataatag gtgtattgct aattggaatt
    13081 gcgttactaa gtcaaaaaaa ataaattttg aaatagtatt agtgagttcg caatcattta
    13141 ttgctagtgg tttagaactg ttaagtttca agcaataatt ggttttaaac cttaggtaac
    13201 ctataaaaac aaataaggta gagaaaggat atcttattta ggtaactaag tactataaac
    13261 acagtcgaca atcacttgtt aggaaaccat cctaactatg cttaataaaa aaggagaaaa
    13321 taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga gatgatgtat
    13381 tttgatgggg gattttctat tccgagatgg cctgttgcaa cagccattaa tatagctttt
    13441 aatgatgtct taggtggagg agcaatcagt ctagttagaa attatattcg taattatggt
    13501 ttgcggcgag ttacaagcgc aattgctgga gcagctgcaa gatatgttgg ggtacgagtt
    13561 gcaaatagag tggcaggatt tgcactgtct gctattaatg gatttgcagc ttggatgtca
    13621 attggcaatg ctattacaac aatctgggcc aataatgatg taaataggag agacccaaat
    13681 ttaaacgcct tgtggtaact agatatgggt attaaaatgg aaaaaatttt tgttattatt
    13741 ttttttgtat gtctatttat atcatccata acttttttag cctatgattt tgttagcgaa
    13801 gaaataaaaa agttgattat ttggatgaat gtcgtttttt tgattttaat catagcaatg
    13861 ataatttatc caaaattaag aaaatgataa ggacactgta aaattatgat acgtaaacta
    13921 atcatttttt tattaatgct ccctcttttt gtcttgtggc tagagttgca tgtcctagtg
    13981 aataacttac tattgaatct agaatctccc cttgattttg tgattagtat gagtcctgct
    14041 ttctgtagtt tgattttatc aaaaatagtt ttagacatac tatacgcatt gaaagatttg
    14101 tacaagaaag aagctcttat tacgattttt ccttttattt ttataggcag gaagaaagta
    14161 aatgtgaggt tctcgcccta tttttcattc catcgtaaaa gtttgtcgcc tgatgattta
    14221 agatctagga ttatatggag ttttattctt gaaattgcta ttatcctagt atttatttta
    14281 aaaattcctt ttgcaatcat catgcttact acaatatttt tctggactat aatggatatc
    14341 aatcatctcg tttttaataa gacggaattt ctttttaatc aaaacaaatg gcaaaaagaa
    14401 gattcgtttg aaagtgattt gacgaaaacg ttaaaggata agatacaaaa atcagagcta
    14461 agttattctg acttaatgtc tcttcagctg tatgatgcga tgaaccaatc caccttttta
    14521 acggatagtg aactttttga ggatattttg aaaaaaatcg aagattctca taacaccctt
    14581 ctgtgtacag gtcttgtcga gttactgctg tatgaaattt ctattagtaa caataacaac
    14641 tggcaagaaa aggttgataa aattagaata cagctcatca gaatcaatca attagatttt
    14701 ttctattata caagttggtt aaggcaaaat tttgatttct gtatgaatag agagtatcat
    14761 aaaatgaaat ctcggaaatt attactgagt aataaaaaga tagtttaagt tcgtcctatt
    14821 tgtaaaacaa atgaaacaat ttcaactaag gaggagaaaa caaatggaac ttgtattacc
    14881 aaataattat gttgtgattg atgaagaaga aatgatgtat cttgatgggg aagcttattt
    14941 aagcaagcgt gcttgtcaag gaatttgcgc agctttagct atgagttcag gaacttttat
    15001 agcattagct ggagctgcag ttttaaccaa aaaactaata aactatatta aggttggagg
    15061 tcttggaggc tggcttattg gtgcagcagc aggtgtattg gctacagcag cagggaaaat
    15121 agcttactat attggatatg gtgttcttaa tagaggttgt gatattaacg ggaaccctta
    15181 tccttgggat ggattcatat ctgcgacagt aaaatgagta atgtagataa gattcgaaaa
    15241 atacacatta tcgtatgttg gatgtatata tttttatcat tcagggcgat tataaatgac
    15301 acggagtatt ttttgcttat ttttttagct tttatctact caatagtatc actacctcta
    15361 tattctgtga aaaataaaat agtatctatc tgtctagcca taaattcgat tctgttaatg
    15421 agtttcccca ttttaatcaa taagtttttc ccagaaagtt ttttgactta taccgtatta
    15481 ataagtgttt ttattacaga gttgataatt tttcatttaa ttgggaaaga ttttgatatt
    15541 aaattgacta acgaatataa gaaaattagt cagtttagaa gcaaggtgtc tcaatctcct
    15601 tggataaaat atttagagat ttctagtttt atattaacta tatttccatc tattctttat
    15661 ggtacagttg ataatcatgt actgactctt atctttttga taaaaatttg tgcagatacc
    15721 acgataaaat ttttattcat cagattattt gacacaagta ctttaatgaa gaggagaata
    15781 ttttttcttt tcgcattgga tgttatagct tacttatttt taggatatct tttagtgatt
    15841 caaaaagcag gctatttgtt ttcggtttta cttctttttt ctaatttttc agttccattt
    15901 atcaaagaaa aggaattcga attatttaaa aatagcaagt aatagaaaca taggttaaat
    15961 cttagaacgg cttaaaatca gatatgataa agggaaatag tcttatctag gtaactaagt
    16021 gctacaaaca caatcgagga tcacttgtta ggattacatt ttaatcatgc ttaataagaa
    16081 tggagaattc ctatggggat tgtattactc tgaagtttcg aataccttag ttctcgtgat
    16141 tttgagctat tctaggttta gaatccttca gaatgtaaaa ttttaagcag tcaaagactt
    16201 agaatagccc gaaaacattt attttatagc aattctaggc ttagaattgc tcatatatat
    16261 gtatttgagc tgctcgatag ttaggatagc tctattctga gaaatctgag ctatcaatgc
    16321 ttcagaatag tattcgccaa tggtttttat tgaagaggtg attgttttat gatagtctaa
    16381 aataaaactg atttaataga gtaaatggag aatcgttaca tgaaacattt ttttgcagga
    16441 attggtgaga taaaacttgt tggctactta ttgtatatat gtgtaggact agctcctctt
    16501 tttcatatat atgtcatagg ttcggaactg agttttgtga aaatagtgtt atctattttg
    16561 ggagttatat ttgtaagtat gttaactatt gctcgaattt atcggacttt tctataaaga
    16621 atagtttgga cttgaactgt atctaaaaac agaggttggt cgattatcag cctctttctt
    16681 gtcgttgaaa agagtgagat atattgactt ttgaaaaaag atgtcataat tgagttggga
    16741 taaatctaaa aataatatag tagattgaat ctggaatagt ccgttatgac tgttaaaata
    16801 tttctagaaa ttaatttgac tttcctaatc gatttgttca tatcttgttt caatctacta
    16861 tactttctcg ttaaaccgtt cggcaattca tggtgacatg gacacatagt agtaagcaca
    16921 ctatgtggct tggcagatct aaaaactgtt cccttgcgat aagcctaata agcacaacat
    16981 agggagttag agaagccgac tctaatcaac cactttgggc agtagtgaga actgccccgt
    17041 gctttttatt ttgagaaaat atggagtttg tcgttgaaat tacttgattg tattttggat
    17101 tatcaagaaa gattcaatgg aaaaacatgt caagtatcaa cgaattataa gtatttagag
    17161 actttcaaag tgaatttttg cttgactgat ttacatcatt tatttgactt acacaaaatc
    17221 acacgagatt atgctggtca aacaaaacct gctattcaag ctggtgtttt tattttagaa
    17281 gattttagaa atatcctatg tacaatgatg taatcgaaag gatatcttta tgtgagttta
    17341 tcggcgatat cttctatatc taagctagca agttgttgca tcgtagctaa ggatttatct
    17401 aaaaatacta tgaaattgga cgtcatattt tttgaggata aaaataaaag atccgcagtt
    17461 ttaggtttac gaagagacaa aagcggagta tttaaaccag ttactctaca ttttacaagc
    17521 gctaagaaat atgctaaagt tcgtaaaaca gatgtgaaag aaatgaaatg gctataaaga
    17581 ttgtccgcag gcttaagctt gcgttttttg ttgtttaacg aaattaaaaa acaagctctc
    17641 tcatcggaaa tgtttttata ggaatgaagg aagatgatgc tatgtttaaa aagagaatcg
    17701 aaaagggcaa aagtagtgtc tttatctttt tggagtagaa gcttatgata tagaaatttg
    17761 taataaaaat gtaatataaa acatttgaca aatatttacg gggggagtat acttaatata
    17821 agtatagtct aaaaatgact atcagaaaag aggtaaattt agatgaataa gaaaaaaatg
    17881 attttaacaa gtctagccag cgtcgctatc ttaggggctg gttttgttgc gtctcagcct
    17941 actgttgtaa gagcagaaga agcccccgta gctagtcagt ctaaagctga aaaagactat
    18001 gatgcagcga agagagacgc tgagaatgcg aaaaaagctt tagaagaagc aaaacgtgcg
    18061 cagaaaaaat atgaggatga tcagaagaaa actgaggaga aagcgaaaaa agagaaagaa
    18121 gcttctaaag aggaacaagc tgcaaatctg aaatatcaac aagagttggt taaatatgct
    18181 agtgaaaaag attcagtaaa aaaagctaaa attctgaaag aagtggagga agctgagaaa
    18241 gagcataaga aaaaacgagc agaatttgag aaagttagat cagaggtaat tcctagcgcg
    18301 gaagagttaa aaaagactag acaaaaagca gaagaggcta aagcaaaaga agcagaactt
    18361 attaaaaaag tagaagaagc tgagaaaaaa gttactgaag ccaaacaaaa attggatgct
    18421 gaacgtgcta aagaagttgc tcttcaagcc aaaatcgctg agttggaaaa tgaagtttat
    18481 agactagaaa cagaactcaa agggattgat gaatctgact cagaagatta tgttaaagaa
    18541 ggtctccgtg ctcctcttca atctgaattg gatgccaaac gaactaaact atcaacactt
    18601 gaagagttga gtgataagat tgatgagtta gacgctgaaa ttgcaaaact tgaaaaaaat
    18661 gtagaatatt tcaaaaaaac cgatgctgag caaactgaac aataccttgc tgcagctgaa
    18721 aaagacttag ctgataaaaa agctgaattg gagaaaactg aagctgacct taagaaagca
    18781 gttaatgagc cagaaaaacc agctgaagaa actccagctc cagcaccaaa accagagcaa
    18841 ccagctgaac aaccaaaacc agcgccggct cctcaaccag ctccagcacc aaaaccagaa
    18901 aaaacagatg atcaacaagc tgaagaagac tatgctcgta gatcagaaga agaatataac
    18961 cgcttgcccc aacagcaacc gccaaaagca gaaaaaccag ctccagcacc aaaaccagag
    19021 caaccagttc ctgcaccaaa aacaggctgg aaacaagaaa acggtatgtg gtacttctac
    19081 aatactgatg gttcaatggc gacaggatgg ctccaaaac
//
LOCUS       DAVBNN010000038        18303 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBNN010000038 DAVBNN010000000
VERSION     DAVBNN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18303
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.038"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            161..475
                     /locus_tag="VQ847_001403"
                     /pseudo
     CDS             161..475
                     /locus_tag="VQ847_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            652..1311
                     /locus_tag="VQ847_001404"
     CDS             652..1311
                     /locus_tag="VQ847_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3050733.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1336..2403
                     /locus_tag="VQ847_001405"
     CDS             1336..2403
                     /locus_tag="VQ847_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3050734.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2506..3516
                     /locus_tag="VQ847_001406"
     CDS             2506..3516
                     /locus_tag="VQ847_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050735.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3528..5219
                     /locus_tag="VQ847_001407"
     CDS             3528..5219
                     /locus_tag="VQ847_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3050736.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5222..5932
                     /locus_tag="VQ847_001408"
     CDS             5222..5932
                     /locus_tag="VQ847_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3050737.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6028..6219
                     /locus_tag="VQ847_001409"
     CDS             6028..6219
                     /locus_tag="VQ847_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050738.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6504..7505
                     /locus_tag="VQ847_001410"
     CDS             6504..7505
                     /locus_tag="VQ847_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3050739.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8646..10007
                     /gene="trpE"
                     /locus_tag="VQ847_001411"
     CDS             8646..10007
                     /gene="trpE"
                     /locus_tag="VQ847_001411"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3050740.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10004..10570
                     /locus_tag="VQ847_001412"
     CDS             10004..10570
                     /locus_tag="VQ847_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3050741.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10581..11585
                     /gene="trpD"
                     /locus_tag="VQ847_001413"
     CDS             10581..11585
                     /gene="trpD"
                     /locus_tag="VQ847_001413"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3050742.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11582..12349
                     /gene="trpC"
                     /locus_tag="VQ847_001414"
     CDS             11582..12349
                     /gene="trpC"
                     /locus_tag="VQ847_001414"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3050743.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12336..12935
                     /locus_tag="VQ847_001415"
     CDS             12336..12935
                     /locus_tag="VQ847_001415"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3050744.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12913..14136
                     /gene="trpB"
                     /locus_tag="VQ847_001416"
     CDS             12913..14136
                     /gene="trpB"
                     /locus_tag="VQ847_001416"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3050745.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14129..14905
                     /locus_tag="VQ847_001417"
     CDS             14129..14905
                     /locus_tag="VQ847_001417"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3050746.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14877..14978)
                     /locus_tag="VQ847_001418"
                     /pseudo
     CDS             complement(14877..14978)
                     /locus_tag="VQ847_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15207..15347
                     /locus_tag="VQ847_001419"
     CDS             15207..15347
                     /locus_tag="VQ847_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050747.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15384..15938
                     /locus_tag="VQ847_001420"
     CDS             15384..15938
                     /locus_tag="VQ847_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050748.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15953..17104
                     /locus_tag="VQ847_001421"
     CDS             15953..17104
                     /locus_tag="VQ847_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3050749.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17156..17815)
                     /locus_tag="VQ847_001422"
     CDS             complement(17156..17815)
                     /locus_tag="VQ847_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3050750.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17885..>18303
                     /locus_tag="VQ847_001423"
     CDS             17885..>18303
                     /locus_tag="VQ847_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050751.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5901 a         2958 c         3937 g         5507 t
ORIGIN      
        1 tattatcgct taccaatatt tgcttttata tttgctaaac tttcagaaaa aaagttggag
       61 tatatgatgc taggtgactg cgtcatgtta ataaacgaaa tggaaataac tgatcataga
      121 gtagataact tatttgaaaa agggaaaaat gagataaaag atccatgtag tagatttagc
      181 aataggacat ataaaagctt tagaaaaagt atctgaaaaa acagatgttt atatctataa
      241 cctaggctcg ggagaaggca ctagtgtatt acaacttgta aatacatttg aaagtgttaa
      301 taagatccct attccttata aaatagttcc aagacgttca ggagacgttg caatttgtta
      361 tgcaaatgca gacaaagcat ataaggaatt aaattggagg acaacaaaat cgattgaaga
      421 catgtgtaga gatacatgga attggcaatc aaaaaatccc aatgactata attgatgata
      481 ctgtctatat gagtgctgta ttttggaaaa attacttaac cttttaatga aatgcatatt
      541 taatgaaaga taaataaaaa aagtttgaca gcgcttgaca aaggaaacgg tttcattgta
      601 taatgtaaac atggtgacac cgatgtcaaa tataaaaaag aaggtcttta tatgaaaaac
      661 ttaacaaaaa ttaagttcaa agagaatggg gaatttaatc atttctctgg gaatacagtt
      721 gtagcaaatc tttatactaa acaagatttg atggaagttg ttgatattat tcaatcacgt
      781 tatagagaat taccatttat cgataagttt actttaactc caaggaattc tattcacatg
      841 actgtaattg aattgttgtg ccatgaaaat cgtgaaacgg agttttggag cagtaatctt
      901 cctctagata cacctttaca ggaaatacat gattactttg ctaaacaact tgaaattttt
      961 ccattgttgg atgaagaaat tcatatgcgt ataactgaaa tgggaaaaca aaacatacta
     1021 gttgaacctg cagatgaagc ttctgcaaag agattagaag aaattcgtac ttatgtctca
     1081 gaaaaagcag gtgtttgttt ccctaatcat gatagatatc aattccatat ttcaattggg
     1141 tatcttcgga ttcctctaac cgaagaggag gaagaagagt ttactaaagt cagagcagaa
     1201 ttaactgaaa ttttattaga gaagattcca actattactg taaaccgtat tgactatact
     1261 gtatttgaag atatgagaca atttgttcca tatcacgaaa aatttaaata aaataataaa
     1321 aaaggagaac ttatcatgaa aaaaatgaaa gtttggtcta ctgtacttgc aacgggagtt
     1381 gctcttacta cacttgctgc ttgctctgga ggttcaaatt ctacgactgc ttcttcatct
     1441 gaagaaaaag ctgataaaag tcaagaatta gtaatctatt cgaactcagt ctcaaatggt
     1501 cgtggtgatt ggttaactgc taaagcaaaa gaagctggtt ttaatataaa aatggttgat
     1561 atcgctggcg ctcaattagc agaccgtgtt attgctgaga agaataatgc agttgcagat
     1621 atggtatttg gaattggtgc tgttgactca aataaaatta gagatcaaaa attactagta
     1681 cagtacaagc ctaaatggtt agataaaatt gatcaatctt tatcagataa agataattat
     1741 tataatcctg tgattgttca accattagtt ttaattgggg cgcctgatgt aaaagaaatg
     1801 cctaaagatt ggactgaatt aggtagtaag tataaaggta aatattcaat ttatggtctt
     1861 caaggtggta caggacgggc aattctagca agtatcttag ttcgttacct tgatgaaaaa
     1921 ggagatttag gcgtatcaga aaaaggatgg gaagttgcaa aagaatactt tgcaaatgcc
     1981 tatactcttc aaaaaggtga aagctcagtt gttaaagcgt tagataaaga aagcccaatt
     2041 caatacggta tgatctgggg ttctggagcg ttaatcggac aaaaagaaca aaatgttgaa
     2101 ttcaaagtta tgactcctga gattggtgta ccatttgtaa ctgaacaaac tatggtttta
     2161 agcactagta aaaaacaagc gttagctaaa gaatttattg attggtttgg tcaatcagaa
     2221 attcaagtag aatatagtaa aaaatttggc tctatccctg ccaataaaga tgccctaaaa
     2281 gagttacctg aagatacgaa aaaatttgtt gatcaagtga aaccacaaaa tattgactgg
     2341 gaagctgttg gaaagcattt ggatgaatgg gtagaaaaag ctgaattaga atacgtacaa
     2401 taagaaataa gagttatttt ttatgtccaa gtctctctat tatttctaaa tttatggaag
     2461 aaataaagag aggcttttgg tttagtaata gagggagtta gtgagatgat taaatttgat
     2521 aatattcaaa ttaaatatgg tgattttgtt gcaattgata atctgaattt agatatacat
     2581 gaaggggaat tctttacatt tcttgggcct tcaggatgtg gtaaatcaac tactttgaga
     2641 gcattggtag gttttttaga tccatcatca ggaagtattg aagttaatgg aacagatgtc
     2701 actcatttgg aacctgaaaa gcgtggaatt ggtattgtat ttcaatctta tgcgctattt
     2761 ccaactatga ctgtttttga taatattgca tttggtttaa aagttaagaa ggtagctcca
     2821 gatgttatta aagctaaagt atcagcagtg gcagcaaaaa ttaagatctc tgatcaacag
     2881 ttacagcgta atgtatcaga attatctggg ggtcaacaac aaagggtagc attggctcgt
     2941 gctctggttc ttgaacctaa aattctttgt ctagatgaac cattgtcaaa ccttgacgca
     3001 aaattacgtg tagatttgag aaaagagttg aaaagacttc aaaaagagtt aggtattact
     3061 actttatatg ttactcatga tcaagaggaa gccttgactt tatctgatag aattgcagtc
     3121 tttaacaatg gatacatcga acaggtcggt acaccagtag agatttatca taattctcaa
     3181 actgaatttg tatgtgattt tattggagat attaatgttt tgaccgatga aacagtccac
     3241 gaagtattac tgaaaaatac aagcgttttc ttagaagata aaaaaggata cattcgatta
     3301 gagaaagttc gattcaatcg tgaaactgaa caagatttca ttctaaaagg gacaattatt
     3361 gatgttgagt tttctggagt tacaattcac tatacaataa aagtttctga aagtcagatt
     3421 cttaatgtaa caagtattga tagtcaggct gctattagat ctgtcggaga aagtgtggaa
     3481 ttatttatca caccatcaga cgttctgcaa ttttaaggag gtgcagtatg cgtcataaat
     3541 taaatttaaa agattggctt attcgtttag ggttaatctg gttcttagta acatttatta
     3601 tttatccaaa ctttgatcta gtagtgaatg tatttgtaaa aggaggagaa ttttcccttg
     3661 atgctgtaca tcgtgttcta aaatctcaga gggcacttca gagtattatg aacagtttta
     3721 agttagcatt ttcactcatt attacagtta atgtcgtagg tattctttgt gttctattta
     3781 cagagtactt tgatattaaa ggtgctaaaa ttttaaaatt aggttatatg acctctttaa
     3841 tttatggagg agtggtttta gcgactggat ataaatttgt ctatggtcct tatggattga
     3901 ttacaaaatt tttacaaaat gttatccctt ctttagactc taactggttt attgggtatg
     3961 gtgcagtctt attcattatg acattttcag gaactgctaa tcatacattg tttttaacaa
     4021 atacaattcg aagcgttgac tatcacacta ttgaggctgc tcgaaatatg ggagcaaaac
     4081 catttactgt tttccgaaaa gtagtgttac caaccttaat tccaactcta tttgcactta
     4141 ctattatggt ttttcttagt ggtttatctg cagtagcagc acccatgatt gttggtggta
     4201 aagaatttca aactataaat ccaatgatta ttacatttgc agggatgggg aattctcgtg
     4261 atttagctgc cttacttgca attattttag gtattgcaac tacaattttg cttactatca
     4321 tgaataagat agaaaaaggt ggaaattata tttctatctc taagactaaa gcgcctctta
     4381 aaaaacaaaa aattgcgtct aagccttgga atatcattgc tcacattgta gcatatggat
     4441 tgttcacagt tttcatgctt ccactaattt ttatagtatt atactcattt acagatccag
     4501 ttgcaattca aacaggtaac ttaacattat caaactttac tttagaaaat tatcgcttat
     4561 tctttagtaa tagtgcggca ttctctccat tcttggtcag ctttatttat tctattattg
     4621 ctgcgacaac agcaacaatt ctcgcagttg tatttgctcg tgttgtcaga aaacataaat
     4681 ctcgttttga tttcttattt gaatatggtg ctctacttcc ttggttacta ccaagtacac
     4741 ttttagcagt aagtttatta tttactttta atcagccaca atttcttgtc ttgaatcaga
     4801 ttttggtagg tagtttggta attctactta ttgcatatat agttgtaaaa atcccatttt
     4861 cttatagaat ggtacgtgct attttattta gtgttgatga tgagatggaa gatgcagcaa
     4921 gaagtatggg tgcttcacct ttttatacta tgatgaaggt tatcattcca tttattttac
     4981 cggttgttct ctctgttatt gctttaaact ttaactcttt attaactgac ttcgacttat
     5041 ctgtattcct ttaccatccc ctagctcaac cattaggtat tacgattcga tctgcaggtg
     5101 atgaaacagc aacatctaat gcacaagctc tggtatttgt ttatacaatt gttctgatga
     5161 ttatttctgg aacggtatta tacttcacac aaagaccggg gcgtaaagta aggaaataat
     5221 catgacagcc actagtcttg ggttatcaaa tattgaaata gttgtcagga ttgttttatc
     5281 agtagtcatt ggtagtataa ttggtttaga gagagggagc aaatcccagc ctgcaggcat
     5341 ccgaacttat agtattgttt gtctagctgc atgtttgatt atgatgacga atgaatacgt
     5401 atcttataaa tttgggacag gagatcctac acgattagga gctcaagtta tatcaggtgt
     5461 gggttttcta ggcgctggaa cgattcttat tacagataaa aagaaaatta caggtctgac
     5521 aactgcagca ggcatttggg cttcggcagg aattggatta gctattggag taggttttta
     5581 tgagggagct cttttagtag ctatttctgt ttggggtgtg atatccatgt tccaaccact
     5641 aaaaaaatat ctgcaaaatc gttctaaaat gattgaattg tatatagtgg ttaaatctac
     5701 agaagcctat aatcgtgtat tggtttattg tgcagaaaat ggtatcagaa tgaccgattc
     5761 aagaacagcg tttggagatg ttaattctga cagaattgaa tactttgatg ttccagataa
     5821 aaaaatagcg tcatttatta ctctggaatt atcaggtaga tttgaacatc ttcgactgat
     5881 ggaagaaatt gctaatattg taggtgttat ttatgtcgaa gaaattagct gaaatttagt
     5941 aaacaaaggg acagatgttt ttgtcctttt gttttttaga tgttttaatc atctaatttt
     6001 tgagtagatt tttgctcaga ggtttttatg aaagattata aaatcaattt tgatttaggt
     6061 aaaatagaat attttgataa taattgtttg atacaagtat acaaatttat ttctttttat
     6121 gatatttgtg aaatggtgtt tgcctttcat ttacctcctg atgagttgat aacaaatgtt
     6181 atctttaaag aaaaaattaa ctctatgtta aaatgttaaa ttgacaggct attatatgtt
     6241 tttataaatc ctacacattt tactgaaaaa gttaatctac aattttatgg tagttttttc
     6301 tcatatgaat ttatttgtcg tgaagttgga aacattctta aaaataaagg tgtgaaatgc
     6361 aatttaaact tttttgaagg gaaagaatat ttgtaaaatt aattttgtga atttgtggat
     6421 cttaaataat ttactaaatt ctcttgttaa aaaaaattaa atattgtata gtaatattag
     6481 aatgttcgta atggaggact gaaatgaaaa atataaatgg gaaaaaggta actatttatg
     6541 atattgcacg tttatcaggt ttttctccaa aaacagtttc acgagttatt aatggtggag
     6601 taaatgttaa agaagaaact tatcaagcga ttcaaaaagt tatagaggaa ttgtcgtata
     6661 ttccaaatgc gtatgcaaaa aatttaacta aaaaagaagc tataaatata ttgatttctg
     6721 taaaaaaaat cgactctttt cctttaattt ggtttcatac gctgttagat aaagtgttac
     6781 ggacgtgtaa agaatttggt gttaatgcta tagttgagta ctttggagag gaggatacaa
     6841 ttagtaattc aattatatca agcacaggta gcctagtaga tggtgttatt gttttttatg
     6901 aaagtgtaga tgatatcaga attcagtatt taaagaagaa ccatatgcct tttcttgttt
     6961 tcggtgaatc tcaaacgtct ggagtagtct atgtatctaa taataatttt caagctactt
     7021 atgatatgat gaaagctgta actgaagaaa aatttaaaaa tatgtggttg cttatgggag
     7081 gagaatccca tgttaataag gatcgtgaaa gaggtgtgcg ttcttttctg aatgataaaa
     7141 attactttat ggatttaaaa gtcatttatg gcttatctac aattgattca gtttattctt
     7201 atgcaatgca gcacttgact acccaaaatt atccggacat tatttttgtt tcaggagatg
     7261 aaaaggttca aggcttgatt cgtgcgtgct atgagaaagg aattcttatt ccagatgata
     7321 tttctatcat tggatttgat aatattccta tttctcagta ttatactcca gctttgtcta
     7381 caattgctcc caattatgtt aaattggcta aagaaatgat agaaggtgtt ttagcaatta
     7441 ttaaagggga aagtgtcaca tctgttgaag tttctcctaa atttgttagg agacagagtt
     7501 tctagtattg tttaattctt gaaaatccta gtggaaaaga tggagtgttc taaaataagt
     7561 tctgtttagc ctccattcag tttctattga gttggatcca atttctaacg agtgggacat
     7621 gttcatgttc gatctaagga agacatggtc acattcgaat gatattttca aaaaaatcgt
     7681 aaaaaagtct tgacaaagaa aaaacaaagt attaaaataa gttcaacaaa tcagaaaagt
     7741 aactattttt gatcttcagg gagcctgtgg tgattgtgaa taggtggttg gaagtagtga
     7801 aagtgggctg attttgaaaa tgaatttgaa acaatgaaaa ttcggtgcgc acaccttaca
     7861 gtgcagcttg ttgttaaaca aggcagagat gtaaagggat agtcccttta taattgaggt
     7921 ggcaccgcgt taccaacgcc ctcacacgga agtatattct gtgtgtgggc ttttttctat
     7981 ccgtcgtttg ctttatcttt tattagggcc ttaactcgct ttgatgaact tgagttctat
     8041 ctacagctcc ttgcctccta ctaaaagtaa acaaaaaggc tggactaata cgaaaaaagc
     8101 tagtaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg ttgctcaaaa
     8161 cactgttttg aggttgcaga tagaactgac gaagtcagta accataccta cgataaggcg
     8221 acgttgacgc ggtttgaaga gattttcgaa gagtataaag gtgtaccgag atgaacatct
     8281 cttcatcaat gtctctggtc gtggaggcaa ggacctagct gcgattgcag attactagaa
     8341 gctaaaaaat aatagatgga aaaattacag tcttttctct cacagagagc ttgtggttgc
     8401 tgaaaacaag cagagaaagc tgtaaagttg ggttcatctg aaacgagaga agaaaacatc
     8461 attctcaagg gagtgccctt tatcgcacag cctgttacag gaggtatctg agacaggaat
     8521 gagagatagg agaaatccta taattgaggt ggcaccgcga atttcgtcct cacgcaagtt
     8581 attttgcgtg gggatttttc atacagtcgc cacgaactag aattagaact gaaagggaaa
     8641 ttacaatgga acgaatcatt catggagatg tcttatcacc aatcttggct tatatgcgct
     8701 taaaggggca acataaggtt attttagaga gtattccgag agacaaggaa acggctcgtt
     8761 tttctatcct agcctataat ccagtttttg agattaagtt tgaaaatgga gttctctatc
     8821 aaaatggtca agtgattgat cgggatccct tggatttcct ttatgaagtg attcataaga
     8881 gtcagcacca ttcagagctc ccttttggtg gtggagccat tggttttgtg ggttacgata
     8941 tgatttcgct ttatgaagaa attggtcaaa tccctgagga tacaattggg acgccagaca
     9001 tgcatttctt tgtctatgag agctatatgg tctttgacca caagaaggag aagatacatg
     9061 tcatagagga tgcactttat agtgagcgca gtcaagaggc cttggaaaaa tccttgaacc
     9121 aagtgcttga ggaattacgc attcctgctc caaatgaatt tgaagacttg gatttatcac
     9181 cacttgactt caaaccgcat atcgctccac ataagtttga gggaatggta gaaacagctc
     9241 gtgacttgat tcgtaacggt gatatgttcc aatgcgtact cagccagcgc ttctcagcag
     9301 aggttactgg aaatccattt gacttctaca gaaatctccg cgtgactaat ccttctaatt
     9361 acctttattt ctatgatttt ggggattatc aaatcatcgg agccagtcca gaaagtttgg
     9421 tttctgtcaa aaatggcatc gtgacaacca atccgattgc agggacgcga ccaagagggg
     9481 ctacggatga agaagacaag gccttggcga ctgacctcct ctctgatgag aaggaaacag
     9541 cagagcatcg aatgttagta gacctgggtc gtaatgatat tggtcgcatc tctgaaacga
     9601 ccagtgtcca agtcactaag tatatggaag tggagctctt ccgttatgtt atgcatctga
     9661 ccagcgtggt caaggggcgt ttgcttccag aactcactgc catggatgcc ttgaaagcta
     9721 cacttcctgc tggaaccgtt tctggagcac caaagattcg tgctatgaga cgtatctatg
     9781 aactggaaac agaaaaacgg ggcgtatacg caggagcaat cggctacttg tctgcgacgg
     9841 gtgatatgga tttggccatt gccatccgaa ccatgattct caaaaatcaa agagcctatg
     9901 tgcaggctgg ggcagggatt gtctacgact ctatcgccca aaacgaatac caagaaacca
     9961 ttaacaaagc aaaatctatg actagaattg gagaactaag accatgattt tattgattga
    10021 caactatgat tcttttacct ataacttggc ccaatacatt gggaattttg cagaagttca
    10081 ggttctgaga aatgatgatt ccaagctgta tgaagaagct gaaaaagcag atggtctggt
    10141 cttttctcct ggtcctggtt ggccagttga tgctggaaag atggaagaca tgattcgtga
    10201 ctttgcaggc aagaagccga ttctagggat ttgtttaggc caccaagcca ttgcagaagt
    10261 ctttggtggt aagctaggtt tggctccaaa agtcatgcat gggaaacaga gcaatatcaa
    10321 ctttgaagcg ccatctgttt tgtatcaagg tattgaggat gaccgtgcgg tcatgcgtta
    10381 tcacagtatt ttgattgagg aaatgccaga agactttgaa gtgacagctc gttcgactga
    10441 tgaccaagcc atcatgggga ttcaacataa aaacctaccg atttatggct tccagtacca
    10501 tccagagagc attggaacgc cagacggctt gtcttctatt cggaatttta tcgagaaggt
    10561 tgtaaagtga ggaaactagg atgaaagaga ttattgaaaa actagcaaaa tttgaaaatt
    10621 tatcaggtgt ggaaatgacg gatgtcattg agcgtatcgt aactgggcgt gtaactgaag
    10681 cgcagattgc ttctctcctc ttagctctta agatgaaggg ggaaacacct gaagaacgca
    10741 cagccattgc ccgagtcatg agaggacatg cccagcatat tccaactgag attcatgatg
    10801 ctatggacaa ctgtggtaca ggtggggaca agtctttcag ttttaatatt tccacaactg
    10861 cagcctttgt cttggctggt ggcggtattc acatggccaa gcatggtaac cgctcgattt
    10921 cttctaaatc tggttccgca gatgtcctcg aagccttggg aatcaatctt gacctcaaac
    10981 cagctgaact aggtaaggtc tttgataaaa ctggcatcgt ctttctcttc gctaaaaata
    11041 tgcacccagc tatgaaatac atcatgccag ctcgtttgga attgggaatt ccaacgatta
    11101 tgaacttgac tggtccactg attcatccaa tggctttaga aacacagctt cttggaatta
    11161 gtcgtccaga actcctagaa agtacagctc aggttttgaa aaatatgggt cgcaaacgtg
    11221 ccatcgtggt tgctggacca gaagggttgg atgaagctgg cttgaacgga acaaccaaga
    11281 ttgcacttct tgaaaatggc gaaatcagct tgtcaagctt tactccagag gatttgggaa
    11341 tggaaggcta tgctatggaa gatattcgtg gtgggaatgc tcaggaaaat gcagaaattt
    11401 tgcttagcgt tctgaaaaac gaagcaagtc cattcttgga aacgacagtc ttgaatgctg
    11461 gtcttggttt ctatgctaat ggtaagattg atagcatcaa ggaaggagtt gccttggccc
    11521 gtcaagtgat tgctagaggc aaggcccttg aaaaactcag actgttacag gagtaccaaa
    11581 aatgagtcag gaatttttag cacgaatctt ggagcagaag gcgcgtgagg tggagcagat
    11641 gaagctggag caaatccagc ctctgcgcca gacctatcgc ttggcagaat ttttgaagaa
    11701 tcatcaggac cgcttgcagg taatcgctga ggtcaagaaa gctagcccta gtttgggaga
    11761 tatcaatctc gatgtggata ttgtgcaaca ggcccagact tatgaagaaa acggagcagt
    11821 gatgatttcg gtgttgacag atgaggtttt ctttaaaggg catttggatt atctacggga
    11881 aatttccagt caggtagaga ttccgacgct caacaaagac tttatcatag atgaaaagca
    11941 aatcatccgc gctcgcaatg caggtgcgac agttatcttg cttattgtgg cagccttgtc
    12001 cgaagaacgc ctcaaggaac tgtatgacta cgcgacagag cttggtctgg aagtcttagt
    12061 ggagactcac aatctagctg aactagaggt agcccacaga cttggtgctg agattatcgg
    12121 ggtcaacaac cgcaacttga ctacctttga ggtcgacttg cagaccagtg tagatttagc
    12181 cccttacttt gaggaaggtc gctattacat ttctgaatct gccattttca cagggcagga
    12241 tgcggaacga ctagccccat actttaacgg aattttggta gggacagctc ttatgcaggc
    12301 agaaaatgtg gcccagagaa tcaaggagtt gcagattgac aaaggttaaa atttgtggac
    12361 tatcgaccaa agaagcggtg gaaacagccg tttcagcagg agccgactat atcggttttg
    12421 tctttgcacc tagtaaaaga caggtgactt tagaagaggc agctgtgttg gcaaagctta
    12481 ttcctgcaga tgtgaaaaag gttggagtat ttgtttcacc aagtcgggta gaactgctgg
    12541 aagcgattga caaagttggc ttggacttgg ttcaagttca cggtcaggtg gcagatgatt
    12601 tatttgagaa tttgccttgt gccagtattc aggctgtgca ggtagatgga aatgggcatg
    12661 tccccaattc tcaggcagat tatctactct ttgatgcccc tgtggcagga agtggccagc
    12721 cctttgattg gggtcaactg gatacgactg gactagcaca gcccttcttt atcgcaggtg
    12781 gccttaatga agataatgta gtaaaagcaa ttcaacattt tactccctat gcagtagatg
    12841 tatcgagcgg agtggagaca gatggacaaa aagatcatga aaagattaga agatttatag
    12901 agagggtaaa gcatggcata tcaggaacca aataaagatg gattttacgg aaaattcggc
    12961 ggacgttttg tcccagaaac attgatgaca gcagttttgg agttggagaa ggcctaccgt
    13021 gaaagtcagg cagacccaag tttccaagag gaattaaacc agcttttgcg ccagtacgta
    13081 ggacgtgaaa ctcctcttta ttacgcaaaa aacttgaccc agcatatcgg cggagccaag
    13141 atttatctca aacgggaaga ccttaaccat acaggagccc acaagattaa caatgcctta
    13201 ggacaagttt ggcttgccaa acgcatgggt aaaaagaaaa ttatcgcaga aacgggtgct
    13261 ggtcagcacg gtgtggcaac tgcaactgct gcggccctct ttaacatgga atgtaccatc
    13321 tacatgggtg aggaagatgt caaacgccaa gccctcaatg tcttccgtat ggagcttttg
    13381 ggagctaagg tcgaggccgt gacagatggt tcgcgcgtgc tcaaggatgc ggtcaatgca
    13441 gcccttcgtt catgggtagc taatatcgat gatacccact atatccttgg ttctgccttg
    13501 gggcctcatc catttccaga aatcgttcgt gacttccaaa gtgtcatcgg tcgagaggct
    13561 aaacaacagt accgcgatat gacaggtcaa gatctgccag atgccctagt agcctgtgtt
    13621 ggtggtgggt cgaatgctat cgggctcttc catccctttg tagaagatga gtcagtagct
    13681 atgtatggaa ctgaagcagc agggcttggt gtggatacag agcaccacgc tgctaccttg
    13741 accaagggtc gtccgggtgt tcttcacggt tctctcatgg atgtgctcca agatgcccat
    13801 ggtcaaattc ttgaagcctt ctctatctca gcaggtttgg actatcctgg tattggtcca
    13861 gaacattctc actaccacga tatcaaacgt gccagctatg tccctgtgac agatgaagaa
    13921 gccttggaag gattccaact cttgtctcgt gtggaaggga ttatcccagc cttggaatct
    13981 agccatgcta tcgcttttgc ggtgaaattg gccaaagaac ttggaccaga aaagtctatg
    14041 attgtctgcc tatcaggtcg tggggacaag gatgtggttc aagtcaaaga ccgcttggaa
    14101 gcagatgcag caaagaaggg agaagctcat gcctaagaca ctaacagaaa aattgaatgc
    14161 tattaaagca gctggaaaag gaatttttgt tccctatatc atggctggtg accacgagaa
    14221 aggtttggac ggtcttgctg aaacaattca ctttttagaa gatttgggtg tctctgcaat
    14281 tgaagtgggt attccctttt cagaccctgt tgcagatgga cctgttatcg aagaagctgg
    14341 cttgcgcagt ttagcccacg ggacctctac ccaggcttta gttgaaacct tgaaaaccat
    14401 tgaaacagag attccactgg tcatcatgac ctacttcaac cccctctttc agtacggtgt
    14461 ggagaacttt gtcaaagatc tggctgatac agctgtgaag ggcttgatta tcccagactt
    14521 gcctcatgaa catgccaact ttgtagaacc atttttggca gatacagata tcgccttgat
    14581 tcctttagta agcttgacca caggaattga gcgccagaaa gagttgattg aaggcgcgga
    14641 gggattcgtc tatgccgttg ccatcaatgg ggtgacaggg aaatcaggca attaccgtgc
    14701 agatttggac aagcacttgg cgcaacttca tcaagtggcc gacatcccag tcttgacagg
    14761 ttttggtgta tctagtcaag ccgatctgga acgcttcaat gcggtgtcag atggtgttat
    14821 cgtcggttcg aaaatagtaa aagctctcca ccaaggagag ccgattcagg attttatcag
    14881 acaagcagta gcttaccaaa aataatcaaa caagtagcaa gtaagaggaa aggcacgaaa
    14941 ggaagtcttt cctttttctt ttgcaggcga aaggctagtt ttatagtgaa ttgaatctgg
    15001 aatattacac tacggttcct aaaatatttt aagaaagtga tttgaatttc ccaataaatt
    15061 tgttcagttt ttaattgatt ttactataga agatataatt ttctaaatta ctctgacaca
    15121 gaactttaag aaaaagctaa ttattgtagt aatttcttta agaaaatgat ataattcatt
    15181 aaaaagtatt tggaggagga agaattatgt tgaatcagga tctctttgat tcgcttgagg
    15241 cacaaaaaat tgtagatact ttgatgaaag ggcaaaaaga ttatgtagat gaacgtctag
    15301 aaaaaagaga gacaatgata gtgtcgaatg gttatgcatg gacgtgacct aatcatattg
    15361 atactgcatt tgcatcagca gatttgtttg agtataaatt acaattagca ggacagactt
    15421 ggggatattt agaatttgaa acaaatacag aaaaatatgg gaaagtattg ttaattataa
    15481 agggtaagaa gcgacttacg aaccaatttc ctttggtaca aaaaaataag agtggctact
    15541 tatttgaata tgctcagatg aatacacttt atcttaatca acattcttcc tacaaaaatg
    15601 atgaagatag tcattccttt ccaattcaga tggagttagt ttctgatgaa atgattcaag
    15661 aaattgaaca agctactaaa aattcgaata tcgaaaaatt tatgatttta acttatgagg
    15721 cggactcaga aaacaatatt atatctgtag atgttgttat gcctgatgca cgaactggtc
    15781 agttacactt gattcaagat ttgtctgagt atattcaatc aagttcgtac catttcgaag
    15841 aagctaaata tcaagatatt cctaattttt cagaattatc ggaaacagaa gattttgaaa
    15901 ttattccaag aatagaaaaa caagaaggtc aaaagtagta aggagtatgt aaatgtttaa
    15961 tggtcgggta ttgaaagaat tacggctgtt aaatggttta agtagagcag aattagctca
    16021 gagaattaat ttaacggaac aagccatttg gcagtttgag tccaacgaaa cgaaacctaa
    16081 attatcaacc aaaatgcatt tggccaacca atttcatgtt gatttaactt attttgaaca
    16141 ggaagaagag agcattcgat ttgattcttc tgtaattgcc tttagaaatg cagacctagc
    16201 aacacggaaa acaatagata ttcaaactat gtatttacat aaggtagata gtttgattga
    16261 ttattttgaa agttttgtaa ttatacctaa tattataatt catgacctaa gtaatgtagt
    16321 gagtgaatct tatcataagg gagaatccat tgaggaattg gctctttatg ccagggaaaa
    16381 attaggtatt tcaaaagata atcatgattt gctttataaa ttagaacgtt caggcatcta
    16441 tatcgtggaa cgattaatta atggccaagc tgatgcttat agcgcatggt caaaattggg
    16501 aagaccttat attgtgttgg gaacgaataa atcatctgta cgtcgaaatt ttgacttagc
    16561 tcatgagcta ggacatattc ttttacataa atataaagat atgaatgaag atggcgatcg
    16621 tttggagcaa gaagcaaatt attttgcatc atgtttttta ttgccaaaag aagagttttt
    16681 agtcaaattt gaagagaggg ttggcaagcg tgtcagcaat cctgatagtt atattttatt
    16741 gaagtcggat ttgaatgttt cgatacaggc tttagagtat cgagctttta agttaggatt
    16801 attgactcca aagcaacatt cttactttta tcgtcaaatt gcgcaaaaag gttacaaaat
    16861 gattgaacct ttggatgatc aaatttttgt taaaaaacca agcaaagtaa agagtattct
    16921 ggacgtcgtt ttgagtaatc atctagtcag tctagcgact ataatgtcta aacaaagtat
    16981 tcgtttacag tttataagcg aaatattttc agtcgaaatg aaattttttg atcagtatca
    17041 agaagataga agaacagatc gatttgataa catcatccct ttgtacaaaa gaaataattt
    17101 ataatttaac tgtgaaataa tttcatgaag gacatatggc agaaattgga ctttatcaaa
    17161 caagcagtag cttaccaaaa ataatcaaac aagtagcaag taagaggaaa ggcacgaaag
    17221 gaagtctttc ctttttcttt tgcaggagaa aggctaggat acccgtcgca gaagcaaact
    17281 gaatcaagat cagtaactcc gttatgctaa agacgagagc acaagaagct aaaaagagga
    17341 aatcccctgc gcccatgcgg atatcgataa aatgagccaa aattccaaga gcaaggaagg
    17401 agaccatgac cagattccag ccagaggaag ctattaggat taggtggaaa gtcatccaga
    17461 ccagtaaggg atattcctga tggcgaaagt catagatgct caaggtcaaa ccagcggtga
    17521 ttaggacgac ttgccccaag gaaagcaatt cccaagagta aagcagaaag aggagtccta
    17581 agcctagttc aaagagggca taccagacag gatagcggac cttgcagtag cgacagcgaa
    17641 agcgattgaa gacctgtgag agaatcggaa tcaaatctaa gggacgcaag ggagtctgac
    17701 aggaatcgca gtgactggct gaactgataa tggattgctc tggaaaacgg tcaatgacca
    17761 aaccaagaaa ggaagcgaga atgctcccga cgagaaaaaa ataaaaatca atcatactta
    17821 tctattcgta aaaaatggga gaaatagtat aatggagaaa catagataag atggtgagga
    17881 aaagatgaca attcgttttg aagaaaaggt gagtatagaa aacgctcaat ttgtatgcca
    17941 atggtccaac tccctaggca aatcctttca agaacaatgg atgggatcaa ggattccttt
    18001 tctactgacc cttcaagcct tggaagaagt cttttcaatc tttgatgaac aagagtttgt
    18061 gggacttatc cagaaaatca ggctagaaga cagcaatctt catatcggga gattttttat
    18121 caacccccag aaacaggggc aaggcttagg tagccaggct ttaaggaaat ttgttagttt
    18181 ggcctttgaa aatgaagata tagatagtat ttctctaaat gtcttcgagg caaatcaaag
    18241 agctcagaat ctttaccaaa aagaaggatt tgaaatcgtt caaatggttg aagcacctgt
    18301 acg
//
LOCUS       DAVBNN010000039        18176 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBNN010000039 DAVBNN010000000
VERSION     DAVBNN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.039"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ847_001424"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ847_001424"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3050752.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ847_001425"
     CDS             complement(863..2125)
                     /locus_tag="VQ847_001425"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3050753.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ847_001426"
     CDS             complement(2135..3265)
                     /locus_tag="VQ847_001426"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3050754.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ847_001427"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ847_001427"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3050755.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ847_001428"
     CDS             complement(5231..6118)
                     /locus_tag="VQ847_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3050756.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ847_001429"
     CDS             complement(6108..6569)
                     /locus_tag="VQ847_001429"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3050757.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ847_001430"
     CDS             complement(6566..7474)
                     /locus_tag="VQ847_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3050758.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFCRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ847_001431"
     CDS             7467..7664
                     /locus_tag="VQ847_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3050759.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ847_001432"
     CDS             complement(7716..8387)
                     /locus_tag="VQ847_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3050760.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ847_001433"
     CDS             complement(8441..8662)
                     /locus_tag="VQ847_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3050761.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ847_001434"
     CDS             8934..9743
                     /locus_tag="VQ847_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3050762.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ847_001435"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ847_001435"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3050763.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ847_001436"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ847_001436"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3050764.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ847_001437"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ847_001437"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3050765.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ847_001438"
     CDS             complement(13018..14277)
                     /locus_tag="VQ847_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3050766.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ847_001439"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ847_001439"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3050767.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15389..16104
                     /locus_tag="VQ847_001440"
                     /pseudo
     CDS             15389..16104
                     /locus_tag="VQ847_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16070..17545)
                     /locus_tag="VQ847_001441"
     CDS             complement(16070..17545)
                     /locus_tag="VQ847_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3050768.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         5330 a         4168 c         3325 g         5353 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgaca gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccagc acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaat tcgtggataa ccaagtagac
    15361 ttgaaatact acatctggag gtactcccat gctttatgtg ggcattgatg tcgctaaaaa
    15421 taaacacgat gttacagcct tgaatgttcc aggaaaaact gttcttaaac cactcacttt
    15481 ttcaaataat aaagctggtt ttgaactctt agatctgtct cttcgacaac tcaaccaaga
    15541 ctgtctcatc gctcttgaaa ataccggaca ttatgccttt aatctactga acttcctgca
    15601 tgaacaagga tataaagttt acacctgcaa tcctttgctc atcaaggaat ttgccaaatc
    15661 attatcactt cgcaagacta aaacggataa gaaagacgct catggcatcg ctcttaaact
    15721 tctttctgac cccaatcgtg aacaatttca acacgataat cggcaagtag aactaaaaat
    15781 actggctaga catattcatc gtctcaagaa aaacagtctg attggaaagt acaatacact
    15841 cgttgtcttg atatcatctt tcctgagttg gataaaatcg ttggaaagca ttcagaatat
    15901 acctaccaac tcttgacacg ctaccctaat cctcagaaaa ggattgaggc aggatttgat
    15961 aagctgatag aaattaagcg attgaccgct tctaattcaa gggctttttg ccgtgctcta
    16021 aaatcatcgc caaatcatca aattgaaata agaaatagtt tagataaaac tattgacttt
    16081 tcttatagtt tgtctttctc ttaataacgt tgatatgatt gacctctgga tcttccgtcc
    16141 cttggaggga gcaaccacgt tccttggcga attggatata gtctacaatt tctcgtgtaa
    16201 tgcgttcacc aggagccaag ataggaatcc ctggaggata gcacatgaca aattctccac
    16261 agacctgtcc aacagactca tctaaggtca aactttttct ctctgaatag aaggcttctt
    16321 gtggagacag caccaactcg ggctgaatat attctccagc tattaagtcc ttcccatctc
    16381 gtgaatagag tctcttaata tcagccagag caccaaccaa gcgctcgatg tcttggatgc
    16441 ggtcgccgat ggaaatatag gccaagatat tgccgatatc accaaactcg atctgaatgt
    16501 cgtattcgtc tcgcaagagg tcataaacct cgatacctgt taagcctatt ccctgagtgt
    16561 aaactgacaa cttggttaca tcaaaatcac agaccgacac accatctatt aactcttttg
    16621 agtaagcata gtaaccgcca atggcattga tttcatgacg agcgtactcg gatagctcaa
    16681 tgacttcctc aaacgactct ttaccacgaa gggccaagtt gcgacgtgaa atatccaaac
    16741 tagccatcaa taagtaagag gcagatgtag actgggtcag gtttataatc tgacgaacgt
    16801 actcgggatt catctgctcc ccgattaaaa gaagcgaact ttgtgtcaaa ctcccaccag
    16861 acttatgcat ggaaactgct gccatatcag ctcctgcatc catagcagaa attggaagtt
    16921 taccagtgaa atgcaaatgc gctccatggg cttcatctac taaaaccatc atgccagctt
    16981 catgagccat ttctgtcaac ccctttaggt ctgaacagat gccgtagtaa gtaggattgt
    17041 tgattaggat agccttagca tctggatggt cctttatggc ctgtgctact cggtcatttt
    17101 caagacctaa agcgatacca atcttaggat ctacactcat ctcgatatag atgggaatgg
    17161 caccacatag aaccaacgca ttgatagcag atttatggac atttcgtggc agaataatct
    17221 tatctcctgc cttgcaggtt gccagaatca tagtctgcac cgatgaagtt gttccaccaa
    17281 tcattagaaa ggcatggcta gctccaaaag catctgcagc cagctcctct gcatcacgaa
    17341 taatcgaaat aggatggcct aaattatcca agggtttcat cgaattgaca tcaatgccta
    17401 cacatttttc tcctaagagt tcgacaagtt ctggatttcc ccgtccacgc ttgtgacctg
    17461 gaacatcaaa gggaacaatc cttttcttgc gtaacttcac caaggcctca taaattgggg
    17521 cttggttttg atctacctct ttcaaaacat actcctttca atatttttag gaccttatga
    17581 aaactaagga actaaaggtt gactcatgaa aaaagagcag gttttcacct gctctgcaat
    17641 cttctgacgt gtttattttg gtttctgttg agtatgtctg ttcccgatgt ttcctaactc
    17701 tctagtagca aatattacgt actttattga tcgtttcaca agatgacgtg tgctttcacc
    17761 acactaaaaa tttatgaatt aggacaagtg tcctaacatc aacttataaa agtaggcttt
    17821 taaccctatc aataatgtgg cttttcaacc acgcttcggc attcaaccct gcctgtccgt
    17881 aggcattttt tactcgggtt tatatttgct agaaaacatc atctcatttt ctaagcttta
    17941 ttactatatc atgtttttaa gaacttgtaa agtatttttt gataaaaaac aaaaatataa
    18001 tagattgaaa ctagaatagt acacttctgc ttctaaaaca ttattagaaa tagattttac
    18061 tgtcctgatc gatttgttct gttcttgttt cattttacta tatgttcgta aatgaaagtt
    18121 ctataatgaa gttagccacc cagccctcct aaaaattaga tggttcaact agctga
//
LOCUS       DAVBNN010000040        18146 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBNN010000040 DAVBNN010000000
VERSION     DAVBNN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.040"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ847_001442"
     CDS             3..308
                     /locus_tag="VQ847_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3050769.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ847_001443"
     CDS             356..1831
                     /locus_tag="VQ847_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3050770.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1857..1934
                     /locus_tag="VQ847_001444"
                     /pseudo
     CDS             1857..1934
                     /locus_tag="VQ847_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2136..8837
                     /locus_tag="VQ847_001445"
     CDS             2136..8837
                     /locus_tag="VQ847_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3050771.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9085..9941)
                     /locus_tag="VQ847_001446"
                     /pseudo
     CDS             complement(9085..9941)
                     /locus_tag="VQ847_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10152..10511)
                     /locus_tag="VQ847_001447"
     CDS             complement(10152..10511)
                     /locus_tag="VQ847_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3050772.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10603..11559
                     /locus_tag="VQ847_001448"
                     /pseudo
     CDS             10603..11559
                     /locus_tag="VQ847_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11543..12100
                     /locus_tag="VQ847_001449"
     CDS             11543..12100
                     /locus_tag="VQ847_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3050773.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12093..12347
                     /locus_tag="VQ847_001450"
     CDS             12093..12347
                     /locus_tag="VQ847_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050774.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12359..14413
                     /locus_tag="VQ847_001451"
     CDS             12359..14413
                     /locus_tag="VQ847_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3050775.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14592..15452
                     /locus_tag="VQ847_001452"
     CDS             14592..15452
                     /locus_tag="VQ847_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3050776.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15671..16381
                     /gene="ccdA2"
                     /locus_tag="VQ847_001453"
     CDS             15671..16381
                     /gene="ccdA2"
                     /locus_tag="VQ847_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3050777.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16401..16967
                     /locus_tag="VQ847_001454"
     CDS             16401..16967
                     /locus_tag="VQ847_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3050778.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16978..18090
                     /gene="msrB"
                     /locus_tag="VQ847_001455"
     CDS             16978..18090
                     /gene="msrB"
                     /locus_tag="VQ847_001455"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3050779.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5462 a         3456 c         3989 g         5239 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tggaccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgtta atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatacaatt
      601 gagtattacc gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tctttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat tggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtacactt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aagctagccg caggttgctc aaaacacagt tttgaggttg
     1921 tagataagac tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg
     1981 aagtcagtaa tcatatctac ggcaaggcga cactgacgaa gtttgaattg gattttcgca
     2041 gagtgtaaat tgttgaaact aggttgtcat accatgtata ccacttgggc tttagtagta
     2101 gctaactgca ctaaatataa tataaggagg gttttatggg gaaaggccat tggaatcgga
     2161 aaagagttta tagcattcgt aagtttgctg tgggagcttg ctcagtaatg attgggactt
     2221 gtgcagttct attaggagga aatatagctg gagaatctgt agtttatgcg gatgaaacac
     2281 ttattactca tactgctgag aaacctaaag aggaaaaaat gatagtagaa gaaaaggctg
     2341 ataaagcttt ggaaactaaa aatgtagttg aaaggacaga acaaagtgaa cctagttcaa
     2401 ctgaggctat tgcatctgag aagaaagaag atgaagccgt aactccaaaa gaggaaaaag
     2461 tgtctgctaa accggaagaa aaagctccaa ggatagaatc acaagcttca agtcaagaaa
     2521 aaccgctcaa ggaagatgct aaagctgtaa caaatgaaga agtgaatcaa atgattgaag
     2581 acaggaaagt ggattttaat caaaattggt actttaaact caatgcaaat tctaaggaag
     2641 ccattaaacc tgatgtagac gtatctacgt ggaaaaaatt agatttaccg tatgactgga
     2701 gtatctttaa cgatttcgat catgaatctc ctgcacaaaa tgaaggtgga cagctcaacg
     2761 gtggggaagc ttggtatcgc aagactttca aactagatga aaaagacctc aagaaaaatg
     2821 ttcgccttac ttttgatggc gtctacatgg attctcaagt ttatgtcaat ggtcagttag
     2881 tggggcatta tccaaatggt tataaccagt tctcatatga tatcaccaaa taccttcaca
     2941 aagatggtcg tgagaatgtg attgctgtcc atgcagtcaa caaacagcca agtagccgtt
     3001 ggtattcagg aagtggtatc tatcgtgatg tgactttaca agtgacagat aaggtgcatg
     3061 ttgagaaaaa tgggacaact attttaacac caaaacttga agaacaacaa catggcaagg
     3121 ttgaaactca tgtgaccagc aaaatcgcca atacggacga caaagaccat gaacttgtag
     3181 ccgaatatca aatcgttgaa cgaggtggtc atgctgtaac aggcttagtt cgtacagcga
     3241 gtcgtacctt aaaagcacat gaatcaacaa gcctagatgc gattttagaa gttgaaagac
     3301 caaaactctg gaccgtttta aatgacaaac ctgccttgta cgaattgatt acgcgtgttt
     3361 accgtgacgg tcaattggtt gatgctaaga aggatttgtt tggttaccgt tactatcact
     3421 ggactccaaa tgaaggtttc tctttgaatg gtgaacgtat taaattccat ggagtatcct
     3481 tgcaccacga ccatggggcg cttggagcag aagaaaacta taaagcagaa tatcgccgtc
     3541 tcaaacaaat gaaggagatg ggagttaact ccatccgtac aacccacaac cctgctagtg
     3601 agcaaacctt gcaaatcgca gcagaactag gtttactcgt tcaggaagag gcttttgata
     3661 cttggtatgg tggcaagaaa ccttatgact atggacgttt ctttgaaaaa gatgccactc
     3721 acccagaagc tcgaaaaggt gaaaaatggt ctgattttga cctacgtacc atggtcgaaa
     3781 gaggcaaaaa caaccctgct atcttcatgt ggtcaattgg taatgaaata ggtgaagcta
     3841 atggtgatgc ccactcttta gtaactgtta aacgtttggt caaggttatc aaggatgttg
     3901 ataagactcg ctatgttacc atgggagcag ataaattccg tttcggtaat ggtagcggag
     3961 ggcatgagaa aattgctgat gaactcgatg ctgttggatt taactattct gaagataatt
     4021 acaaagccct tagagctaag catccaaaat ggttgattta tggatcagaa acatcttcag
     4081 ctacccgtac acgtggaagt tactatcgcc ctgaacgtga attgaaacat agcaatggac
     4141 ctgagcgtaa ttatgaacag tctgactatg ggaatgatcg tgtgggttgg gggaaaacag
     4201 caaccgcttc atggactttt gaccgtgaca acgctggcta tgctggacag tttatctgga
     4261 caggtacgga ctatattggt gaacctacac catggcacaa ccaaaatcaa actcctgtta
     4321 agagctctta ctttggtatc gtagatacag ccggcattcc aaaacatgac ttctatctct
     4381 accaaagcca atgggtttct gttaagaaga aaccgatggt acaccttctt cctcactgga
     4441 actgggaaaa caaagaatta gcatccaaag tagctgactc agaaggtaag attccagttc
     4501 gtgcttattc gaatgcttct agtgtagaat tgttcttgaa tggaaaatct cttggtctta
     4561 agactttcaa taaaaaacaa accagcgatg ggcggactta ccaagaaggt gcaaatgcta
     4621 atgaacttta tcttgaatgg aaagttgcct atcaaccagg taccttggaa gcaattgctc
     4681 gtgatgaatc tggcaaggaa attgctcgag ataagattac gactgctggt aagccagcgg
     4741 cagttcgtct tattaaggaa gaccatgcga ttgcagcaga tggaaaagac ttgacttaca
     4801 tctactatga aattgttgac agccagggga atgtggttcc aactgctaat aatctggttc
     4861 gcttccaatt gcatggtcaa ggtcaactgg tcggtgtaga taacggagaa caagccagcc
     4921 gtgaacgcta taaggcgcaa gcagatggtt cttggattcg taaagcattt aatggtaaag
     4981 gtgttgccat tgtcaaatca actgaacaag cagggaaatt cacccttact gcccactctg
     5041 atctcttgaa atcgaaccaa gtcactgtct ttactggtaa gaaagaagga caagagaaga
     5101 ctgttttggt gacagaagtg ccaaaagtac agaccattat tggagaggca cctgaaatgc
     5161 ctaccactgt tccgtttgta tacagtgatg gtagccgtgc agaacgtcct gtaacctggt
     5221 cttcagtaga tgtgagcaag cctggtattg taacggtgaa aggtatggct gacggacgag
     5281 aagtagaagc tcgtgtagaa gtgattgctc ttaaatcaga gctaccagtt gtgaaacgta
     5341 ttgctccaaa tactgacttg aattctgtag acaaatctgt ttcctatgtt ttgactgatg
     5401 gaagtgtaca agagtatgaa gtggacaagt gggagattgc cgaagaagat aaagctaagt
     5461 tagcaattcc aggttctcgt attcaagcga ccggttattt agaaggtcaa ccaattcatg
     5521 caacccttgt ggtagaagaa ggcaatcctg cggcacctgc agtaccaact gtaacggttg
     5581 gtggtgaagc tgtcacaggt cttactagtc aaaaaccaat gcaataccgc actcttgctt
     5641 atggagctaa gttgccagaa gtcacagcaa gtgctaaaaa tgcagctgtt acagttcttc
     5701 aagcaagcgc agcaaacggc atgcgtgcga gcatctttat tcagcctaaa gatggtggcc
     5761 ctcttcaaac ctatgcaatt caattccttg aagaagcgcc aaaaattgct cacttgagct
     5821 tgcaagtgga aaaagctgac agtctcaaag aagaccaaac tgtcaaattg tcggttcgag
     5881 ctcactatca agatggaacg caagctgtat taccagctga taaagtaacc ttctctacaa
     5941 gtggtgaagg ggaagtcgca attcgtaaag gaatgcttga gttacataag ccaggagcag
     6001 tcactctcaa agcggaatat gagggagcta aaggccaagt tgatctcact atccaggcca
     6061 atactgagaa gaagattgcg caatctatcc gtccagtaaa tgtagtgaca gatttacacc
     6121 aagaacctac tcttccgtca acagtaacgg ttgagtatga caaaggtttc cctaaagctc
     6181 acaaagtcac ttggcaagct attccgaaag aaaaactaga ctcctatcaa acctttgaag
     6241 tactaggtaa agttgaagga attgaccttg aagcgcgtgc aagagtctct gtagaaggta
     6301 tcgtttcagt tgaagaagtc agtgtgacaa ctccaatcgc agaagcacca caattaccag
     6361 aaagcgttcg gacatatgat tcaaatggtc acgtttcatc agctaaggtt gcatgggatg
     6421 cgattcgtat agagcaatac gctaaggaag gtgtctttac agttaatggt cgcttagaag
     6481 gtactcaatt aacaactaaa cttcatgttc gcgtatctgc tcaaactgag caaggtgcaa
     6541 atatttctga ccaatggacc ggttcagaat tgccacttgc ctttgcttca gactcaaatc
     6601 caagcgaccc agtttcaaat gttaatgaca agctcatttc ctacaataac caaccagcca
     6661 atcgttggac aaactggaat cgtagtaatc cagaagcttc agtcggtgtt ctgtttggag
     6721 attcaggtat cttgagcaaa cgctccgttg ataatctaag tgtcggattc cacgaagacc
     6781 atggagttgg tgcaccgaag tcttatgtga ttgagtatta tgttggtaag actgtcccaa
     6841 cagctcctaa aaaccctagt tttgttggta atgaggacca tgtctttaat gattctgcca
     6901 actggaaacc agttactaat ctaaaagccc ctgctcaact caaggctgga gaaatgaacc
     6961 actttagctt tgataaagtt gaaacctatg ctgttcgtat tcgcatggtt aaagcagata
     7021 acaagcgtgg aacgtctatc acagaggtac aaatctttgc gaaacaagtt gcggcagcca
     7081 aacaaggaca aacaagaatc caagttgacg gcaaagactt agcaaacttc aaccctgatt
     7141 tgacagacta ctaccttgag tctgtagatg gaaaagttac ggcggtcaca gcaagtgtta
     7201 gcaacaatgg tctcgctacc gtcgttccaa gcgttcgtga aggtgagcca gttcgtgtca
     7261 tcgcgaaagc tgaaaatggc gacatcttag gagaataccg tctgcacttc actaaggata
     7321 agagcttact ttctcataaa ccagttgctg cggttaaaca agctcgcttg ctacaagtag
     7381 gtcaagcact tgaattgccg actaaggttc cagtttactt cacaggtaaa gacggctacg
     7441 aaacaaaaga cctgacagtt gaatgggaag aagttccagc ggaaaatctg acaaaagcag
     7501 gtcaatttac tgttcgaggc cgtgtccttg gtagtaacct tgttgctgag atcactgtac
     7561 gagtgacaga caaacttggt gagactcttt cagataaccc taactatgat gaaaacagta
     7621 accaggcctt tgcttcagca accaatgata ttgacaaaaa ctctcatgac cgcgttgact
     7681 atctcaatga cggagatcat tcagaaaatc gtcgttggac aaactggtca ccaacaccat
     7741 cttctaatcc agaagtatca gcgggtgtga ttttccgtga aaatggtaag attgtagaac
     7801 ggactgttgc acaaggaaaa gttcagttct ttgcagatag tggtacggat gcaccatcta
     7861 aactcgtttt agaacgctat gtcggtccag agtttgaagt gccaacctac tattcaaact
     7921 accaagccta cgacgcagac catccattca acaatccaga aaattgggaa gctgttcctt
     7981 atcgtgcgga taaagacatt gcagctggtg atgaaatcaa cgtaacattt aaagatatca
     8041 aagccaaagc tatgagatgg cgtatggagc gtaaagcaga taagagcggt gttgcgatga
     8101 ttgagatgac cttccttgca ccaagtgaat tgcctcaaga aagcactcaa tcaaagattc
     8161 ttgtagatgg aaaagaactt gctgatttcg ctgaaaatcg tcaagactat caaattacct
     8221 ataaaggtca acggccaaaa gtctcagttg aagaaaacaa tcaagtagct tcaactgtgg
     8281 tagatagtgg agaagatagc cttccagtac ttgttcgcct cgtttcagaa agtggaaaac
     8341 aagtcaagga ataccgtatc cacttgacta aggaaaaacc agtttctgag aagacagttg
     8401 ctgctgtaca agaagatctt ccaaaactcg aatttgttga aaaagatttg gcctacaaga
     8461 cagttgagaa aaaagattca acactgtatc taggtgaaac tcgtgtagaa caagaaggaa
     8521 aaactggtaa agaacgtatc tttacagcga ttaatcctga tggaagtaag gaagaaaaac
     8581 tccgtgaagt ggtagaagct ccgacagacc gcatcgtctt ggttggaacc aaaccagtag
     8641 ctcaagaagc taaaaaacca caagtgtcag aaaaagcaga tacaaaacca attgattcaa
     8701 gtgaagctag tcaaactaat aaagcccagt taccaaatac aggtagtgcg tcaagccaag
     8761 cagcagtagc agcaggttta gctcttctag gtttgagtgc aggattagta gttactaaag
     8821 gtaaaaaaga agactagaaa ttttgatacc ttctttatca ttaaagacca aagaaaaact
     8881 cttgtcctaa atagaagata aagagtctgg aacaaaatag ttctcaacca caaaaaagct
     8941 agatatttcc aattgcggaa ctctagcttt ttaattttga gtcgttctct gattgtatag
     9001 tagattgaaa ctagagtagt acacttctac ttctaaaaca ttgttagaaa tcgatttgac
     9061 tgtccttatc gatttgtcct gttcttattt gatttcacta tgttttagga ggttattggc
     9121 cataagtacc aatcccatgt caattctcac ttgacgcttg cctctcagat tacatctctt
     9181 gtaacccaaa caagccttta tctgcccaaa gacaggttcc acatcaatct tgcgttgagc
     9241 gaaaatctgt ctatcttggg gagataaaag cgcctgacat tctttagctt tcaagttttg
     9301 atagcgttcg ttcatataca gtcccttttg aggggctgat tcaggttcat cagcgtagta
     9361 aaccttgatt tcctgttgaa agtctgtctg tgttttctgg tacttgatat ggtgaaaacg
     9421 atagcaccag ccatcaggat gtatgtagct atcctccttg tcattatagt gccaattcgc
     9481 taagttttta gctgactgtt tataccctct cttttgtttc ttatcaaaca tggcatattt
     9541 aatcagaagg ggagtgattt cttcttgaaa atagacttgt atctgttctt gaagtttggc
     9601 ggagaatttc tctgtcgttt tcttccacac aaaactatac ttgttggcat tggcttcaat
     9661 cttagttccg tcaataaaca aacaatctaa ggtcactaac tcttccattt ttcaattttt
     9721 cgaccagaga aaatcccttg tgaataggca aatagaagag tagatacaag cattttaagg
     9781 tgataagacg ggcgatcaaa ggcatgatag aaggcgtgga aatgacaatc ctccaaggta
     9841 ttcaccactt tttcaatagt aaaaacgaga tggtcttgtg gcaagaagga actgatttct
     9901 agtggtaaag ttgtttgatt tgtgttatag tgaatatgca tgggatagcc tttctaaatg
     9961 gtttattgtg caattctatt ttaccaagac tatcgcaacc atgcaaaaaa gcaacggcaa
    10021 atccgttgct ttttttggag ataagagact attgtcccag actcttttct ttgtataaaa
    10081 ttgtatagtg ttattgtcta tactattttg tagagaaagc aaaaatccct agaaaatgct
    10141 tagggattcg actatttcat taagaacaat tcaacaatca tttctacata catgataagg
    10201 gttaataaga atcctgcacg ccagaagaat ttgatgaatt taggatagta aaagctgcgt
    10261 tttttcaaaa ggaagaaaaa gacgagaata atggctagga tcgagagggt tagccccagt
    10321 ctagggagga aattatgggt aaaggtttta gctgtaatca agtaatactc aaataccaag
    10381 actggaaaag ccaaatccgc aaagtttcgt cctagttttt ttaatctaaa aagtttggtt
    10441 aggataatgc agatgactaa ggtcagtatc aataataaaa tagatgctaa tttcattaaa
    10501 atcataccca tattgtatca taaaaaaagg ctaatggaaa cgagaaacag aggaatttat
    10561 aagaaagtca ggcttttgag attgtgggtg atttttgtta taatgaaagt tataaaatct
    10621 tataatacct tgaatgatta ttatcgaaaa ctctttggag aaaagacttt taaagtccct
    10681 attgatgcgg gatttgactg tcccaatcgt gatggaactg tggctcatgg aggctgtact
    10741 ttttgtacgg tttcaggttc tggagatgct attgtagccc cagatgcgcc tatccgtgag
    10801 caattttata aggaaattga ctttatacac cgtaagtggc cggatgttca gaagtatctg
    10861 gtttattttc aaaattttac caacactcat gaaaaggtgg aagttattcg agagcgttat
    10921 gaacaggcta tcaatgagcc aggtgtggta ggaatcaata ttggaacgcg cccagactgt
    10981 ttaccagacg aaaccatcga atatttggct gagttatcgg agtgcatgca tgtgacgttt
    11041 gaattgggct tgcaaactac ttatgaagca acctctgacc tgattaaccg tgcgcattct
    11101 tatgaattgt aggtggaaac ggtcaagcgt ttgagaaagt atccaaaaat tgagattgtt
    11161 tcccatttga tcaatggttt gcctggtgaa acccatgaga tgatggttga aaatgtccgc
    11221 cgttgtgtca cggataacga tattcaaggg attaaactgc atttgctcca tcttatgaca
    11281 aatactcgta tgcaacgaga ttaccatgag gggcgtttac aattgatgag tcaggacgaa
    11341 tatgtcaggg tcatctgtga ccaactggaa attattccca aacatatcgt catccatcga
    11401 attacaggag atgcgcctag ggatatgctg cttgggccta tgtggagcct caataaatgg
    11461 gaagctctca acagcattga gatggagatg cgacgtcgtg gaagtgttca aggatgcaag
    11521 gctgtaaaac aggagtttga aaatgaaaag accacttgag atggcacatg attttttggc
    11581 tgaggtcgtg acaaaagagg atgtcgtagt ggatgcgact atgggaaatg gtcatgacac
    11641 gcttttttta gccaagctag ccaagcaagt ctatgccttt gatattcaga agcaagcctt
    11701 ggaaaagacc caagagcgtt tgcatcaggc tgacttgaca aatgcccagt taatcttgca
    11761 aggccatgag acactggacc agtttgtgat aaaagctaag gcagggattt ttaatctggg
    11821 ctatttgccg tcagctgata agtctgtcat cacccgaccg cagacaacga ttgaggcatt
    11881 agaaaagcta tgtggcttac ttgtcaaagg tggacgaatt gctattatga tttactatgg
    11941 tcatgaagga ggcgatctcg agagagatgc tgtcttggat tttgtgatcc agttgaacca
    12001 acaagagtac acagctgcca tttaccgaac tttaaaccaa gtcaacaacc cgccgttttt
    12061 agtgatgatt gaaaaattag agagatacag acatggataa acaatactta cacgaaaagc
    12121 tggatgccat gcgccagaat tttgttgaat caacccacca cgaacgagcg gtgggcgtgc
    12181 tagaccaagc gcatatgagc aaaaaaatgc ttaaaatcaa gaaaaaatta gttgctcttg
    12241 aaatggaacg gtgccagaga aaaattgagc acaaagactg ttccaagatt gaccaaaaaa
    12301 tcaaagagca gaaggagata tttgaatcct gttgtaaaaa agattaagga ggacgtgcgt
    12361 ggaattactg atttacctca tcctattttt actggttttg attgtctcaa gtacaaccaa
    12421 taagctcctg ccctttttgc ctctcccttt ggtgcaaatt cttttgggaa ttgtgattgg
    12481 tctcttttta cccaatactg actttcacct taatacggag ttgtttttgg cactggttat
    12541 cggacccttg cttttccgag aggctgaaga agcagatgtt acggctattt taaaacactg
    12601 gcgaatcatt gtttatctca tatttccagt gatttttatc tcgaccctga gtttgggtgg
    12661 cttggcccat cttctttggt tcagccttcc cttggcagct tgcttggctg ttggggcagc
    12721 ccttggtcct acggacttgg tggcctttgc ctctctttcg gagcgtttta gctttcctaa
    12781 gcgcgtgtcc aatattctta agggcgaagg actcttgaat gatgcttctg gtttggtggc
    12841 ttttcaggta gctttgacag cttggacaac tggagctttt tctctggggc aagctagcag
    12901 ttcgctcatc ttttcaatcc taggcggttt tttaattgga tttttaacag ccatgaccaa
    12961 ccgcttcctc cataccttct tgctaagtgt gcgcgcaacg gatattgcca gtgaactttt
    13021 attagaattg agtttgcctc tagtgacctt ctttctggca gaagaagtcc atgtttcagg
    13081 tattattgcc gtcgtagttg ctggaatttt aaaggcaagt cgcttcaaga aaatcacgct
    13141 cctcgaagcc caagtggata cggtgaccga gacggtctgg catacagtga cctttatgct
    13201 caacggttct gtctttgtga ttttagggat ggagttggaa atgatagcag aacctatctt
    13261 gaccaatcca atctataatc ctctactttt attgctatct ctcatcgccc ttacctttgt
    13321 cctctttgtc attcgtttta ttatgatcta tggctattat gcctatagaa cccgacgcct
    13381 caagaaaaag ctaaataagt atatgaagga catgtttctc ttgacctttt caggtgttaa
    13441 gggaacggtg tcgattgcta cgattctctt gataccaagt aatctagaac aggagtatcc
    13501 tcttttgctt ttccttgttg caggtgtgac gcttgtcagc tttttaacag gtctcttggt
    13561 cttgcctcat ctttctgatg aagaggaaaa aagcaaggat tatctcatgc atatcgccat
    13621 tttgaatgaa gtaacgctag agttggaaaa agagttggaa gacaccagaa ataaacttcc
    13681 cctctatgcg gctattgaca attatcatgg acgtattgaa aatctcattt taagccaaga
    13741 aaaccaggat gatcaagaag actgggctgc tttgaaactc ttgattctta gtattgaaag
    13801 tgatggtttg gaacaggcct atgaagaggg gaacattagc aatcgtgctt accgagttta
    13861 ccaacgttat ctgaaaaata tagaacaagg aatcaatcgt aaacttgcct caagactgac
    13921 ctattatttc cttgtttcct tgaggatttt acgttttctc cttcatgaag tttttactct
    13981 tggaaagacc ttccgtagct ggaaggacaa ggagcaaagc cgtctccgtg ctcttgatta
    14041 tgaccaaatt gcagagctct atcttgccaa tacggagatg attattgaaa gtttggaaaa
    14101 cctgaaggga gtctacagac gctctttgat tagttttatg caggagtctc gtcttcgaga
    14161 aacagctatt atcagcagtg gtgcctttgt cgaacgggtt atcaatcgtg tcaaacccaa
    14221 caatatcgat gaaatgctga gaggctatta tctggagcgc aagttgattt tcgaatacga
    14281 agaaaaacga ttaattacaa ctaagtatgc caagaaatta cgacaaaatg taaataactt
    14341 agagaactat tccttgaagg aagctgccaa taccctgccg tatgatatgg tggaattggt
    14401 aagaagaaat tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttgg
    14461 attatatatg tgactgactt cgtcagtttc atctacaacc tcaaagcagg gctttgagca
    14521 acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga ttataaatga
    14581 aggagtatga catgaaaaag tggtggaaag agctgataga caagccttta ttaaaagctt
    14641 ttttgcatta ttatcaagca tcagatagtg agttgaccag tgtcgcagta gcctactatt
    14701 ggttgatttc gattttcccc ctgcttttgg tggtggtcaa tatcctcccc tattttcaga
    14761 ttcctgtggg agaatttctg tgctttatga aagacgttct gcccccaagc ctctatgaag
    14821 gtgtggaaaa aatagccaga gaagttttga cgcaaccttc aacaggttta ttaagttttt
    14881 ctgttttatc ggcgttatgg agtttttcaa aatctatgaa tttcttgcaa aaagctttta
    14941 acaaggctta tggcgtcgaa aagagtcgtg gacttatttc ccatcagatg ctaagtctcc
    15001 tagtcagttt tggcttgcag ctcctctttg cgtttgcctt gtttttgatc ttatttggtc
    15061 agatgatttt ggctttactt gctcattatt ggacaaaaga tggcattatc tatcaggctt
    15121 tacaagggtt ggcaggtcct ctgatttacg ccctcctctt tgctatcttg gtcatgcttt
    15181 attattttct tcccaatata tctaacagga aaattagcta taccctacca ggcagtgcct
    15241 ttgttctctt agtgatttta ggtttactaa ctctgttctc tagttatctc aattactatg
    15301 tccatcattt ggtggatgtc cgaattttag gttccgttct tcttgttgtt atgatgtttt
    15361 ggtttatctt gattgctaaa attgttatcc taggcgcggt tatcaatgcc agtatgcaga
    15421 gtttgaaaga tccggtcttt aaaaaagact aactatttat ccattataaa agcgcatagt
    15481 atcaagactt tatagaacct tgatactatg cgcttttgcg cttttgtgct ttgacagttt
    15541 tttgtatagt ttttgtccaa gatttctaaa tcatctgatt aaattcctat tttcccctat
    15601 cattgtccct gttttttcga aaatggaagg agtataataa atctatcaat aaaatgatag
    15661 gaggaacttt atgggtcata ttttcttttt tctaagtgtc tttttggcag ggattctatc
    15721 cttcttttct ccttgtatct tacctttgtt accggtctat acaggagtgt tactagatga
    15781 taaggatggt gctcaggctt ctagcggcaa attttcaatc tcagttacta gtttattacg
    15841 aactctggcc tttatagcag gaatttcctt tatatttatt ttgttgggct atggagctgg
    15901 ttttttaggc gatttgcttt atgcttcttg gttccaatat cttactgggg caattattat
    15961 ccttcttggt ttgcaccaaa tggagattct acactttaag gggctttata aggaaaagag
    16021 gctacaactg caaggacagg ggcaaaatgg taagggctat agtcaggcat ttttattggg
    16081 cttgaccttt agttttgctt ggacgccttg cgtggggccg gttctggggt ctgttttggc
    16141 cttggcggct tcaggtggtt caggagcttg gcagggagct ggtctcatgt tggtgtatac
    16201 gctgggcttg gcgctaccat tcttgcttct agctctgacc tctagttatg ttttgaaaca
    16261 tttccgaaaa cttcatccct atctcggaat cctcaaaaaa gtgggtggtt ttctcattat
    16321 tgtgatggga ctcttggttc tgtttggaaa tgcttcaatt ttaagtcaat tatttgaata
    16381 aaatggaaag gaatatcaat atgaaaaaat ggcaaacatg tgttcttgga gcaggttcgc
    16441 tcctttggtt gacggcttgt tcaggcaagt ccgtgactag tgaacaccaa acgaaagatg
    16501 aaatgaagac ggagcagaca gctagtaaaa caagcgcagc taaagggaaa gaggtggctg
    16561 attttgaatt gatgggagta gatggcaaga cctaccgttt atctgattac aagggcaaga
    16621 aagtctatct caaattctgg gcttcttggt gttccatctg tctggctagt cttccagata
    16681 cggatgagat tgctaaagaa gctggtgatg actatgtggt cttgacagta gtgtcaccag
    16741 gacataaggg agagcaatct gaagcggact ttaagaattg gtataaggga ttggattata
    16801 aaaatctccc agtcctagtt gacccatcag gcaaactttt ggaaacttat ggtgtccgtt
    16861 cttacccaac ccaagccttt atagacaaag aaggcaagct ggtcaaaaca catccaggct
    16921 tcatggaaaa agatgcaatt ttgcaaactt tgaaggaatt agcctaggag gtgtcttatg
    16981 aatgataagt taaaaatctt cttgttgcta ggagtatttt ttctagccat aaccggtttc
    17041 tatgttctat tgatacgaaa tgcagggcag acagatgcct cgcaaattga aaaggcggca
    17101 gttagccaag gaggaaaagc agtgaaaaaa acagaaatta gtaaagacgc agacttgcac
    17161 gaaatttatc tagctggagg ttgtttctgg ggagtggagg aatatttctc acgcgttccc
    17221 ggggtgacgg atgccgtttc aggctatgca aatggtagag gagaaacaac caagtacgaa
    17281 ttgattaacc aaacaggtca tgcagaaacc gtccatgtca cctatgatgc caagcaaatt
    17341 tctctcaagg aaatcctgct tcactatttc cgcattatca atccaaccag caaaaataaa
    17401 caaggaaatg atgtggggac ccagtaccgt actggtgttt attacacaga tgacaaggat
    17461 ttggaagtga ttaaccaagt ctttgatgag gtggctaaga aatacgatca acctctagca
    17521 gttgaaaagg aaaacttgaa gaattttgtg gtggctgagg attaccatca agactatctc
    17581 aagaaaaatc caaatggcta ctgccatatc aatgttaatc aggcggccta tcctgtcatt
    17641 gatgccagca aatatccaaa accaagtgat gaggaattga aaaagaccct gtcacctgag
    17701 gagtatgcag ttacccagga aaatcaaaca gaacgagctt tctcaaaccg ttactgggat
    17761 aaatttgaat ccggtatcta tgtggatata gcaactgggg aacctctctt ttcatcaaaa
    17821 gacaaatttg agtctggttg tggctggcct agttttaccc aacccatcag tccagatgtt
    17881 gtcacctaca aggaagataa gtcctacaat atgacgcgta tggaagtgcg gagccgagta
    17941 ggagattctc accttgggca tgtctttacg gatggtccac aggacaaggg cggcttacgt
    18001 tactgtatca atagcctctc tatccgcttt attcccaaag accaaatgga agaaaaaggc
    18061 tacgcttatt tactagatta tgttgattaa tactcttcga aaatctcttc aaaccacgtc
    18121 agcgtcgcct taccgtatgt agggtt
//
LOCUS       DAVBNN010000041        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBNN010000041 DAVBNN010000000
VERSION     DAVBNN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.041"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ847_001456"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ847_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3050780.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ847_001457"
     CDS             complement(881..1867)
                     /locus_tag="VQ847_001457"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3050781.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ847_001458"
     CDS             complement(1830..2630)
                     /locus_tag="VQ847_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3050782.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ847_001459"
     CDS             complement(2880..3260)
                     /locus_tag="VQ847_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3050783.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ847_001460"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ847_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3050784.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ847_001461"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ847_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3050785.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ847_001462"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ847_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3050786.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ847_001463"
     CDS             complement(4805..5989)
                     /locus_tag="VQ847_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050787.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ847_001464"
     CDS             complement(5993..6580)
                     /locus_tag="VQ847_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050788.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ847_001465"
     CDS             complement(6613..6801)
                     /locus_tag="VQ847_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050789.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ847_001466"
     CDS             complement(6980..9220)
                     /locus_tag="VQ847_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3050790.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ847_001467"
     CDS             complement(9204..9854)
                     /locus_tag="VQ847_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3050791.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ847_001468"
     CDS             complement(9922..10491)
                     /locus_tag="VQ847_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050792.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ847_001469"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ847_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ847_001470"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ847_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ847_001471"
     CDS             complement(12409..12909)
                     /locus_tag="VQ847_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050793.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ847_001472"
     CDS             complement(13089..14057)
                     /locus_tag="VQ847_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3050794.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ847_001473"
     CDS             complement(14143..14358)
                     /locus_tag="VQ847_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3050795.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ847_001474"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ847_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3050796.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ847_001475"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ847_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3050797.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ847_001476"
     CDS             complement(15847..16584)
                     /locus_tag="VQ847_001476"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3050798.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ847_001477"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ847_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3050799.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5189 a         4136 c         3374 g         5439 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagtagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtaac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactt
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatatta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBNN010000042        17991 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBNN010000042 DAVBNN010000000
VERSION     DAVBNN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.042"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VQ847_001478"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VQ847_001478"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3050800.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VQ847_001479"
     CDS             1377..1886
                     /locus_tag="VQ847_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050801.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4365
                     /locus_tag="VQ847_001480"
     CDS             1963..4365
                     /locus_tag="VQ847_001480"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3050802.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(4433..5434)
                     /locus_tag="VQ847_001481"
     CDS             complement(4433..5434)
                     /locus_tag="VQ847_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3050803.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5590..6037
                     /locus_tag="VQ847_001482"
                     /pseudo
     CDS             5590..6037
                     /locus_tag="VQ847_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6163..6429
                     /locus_tag="VQ847_001483"
     CDS             6163..6429
                     /locus_tag="VQ847_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3050804.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            6689..8938
                     /gene="metE"
                     /locus_tag="VQ847_001484"
     CDS             6689..8938
                     /gene="metE"
                     /locus_tag="VQ847_001484"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3050805.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9002..9868
                     /gene="metF"
                     /locus_tag="VQ847_001485"
     CDS             9002..9868
                     /gene="metF"
                     /locus_tag="VQ847_001485"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3050806.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10427..12640
                     /gene="pnp"
                     /locus_tag="VQ847_001486"
     CDS             10427..12640
                     /gene="pnp"
                     /locus_tag="VQ847_001486"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3050807.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            12656..13273
                     /gene="cysE"
                     /locus_tag="VQ847_001487"
     CDS             12656..13273
                     /gene="cysE"
                     /locus_tag="VQ847_001487"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3050808.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13285..14169
                     /locus_tag="VQ847_001488"
     CDS             13285..14169
                     /locus_tag="VQ847_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3050809.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14251..15594
                     /locus_tag="VQ847_001489"
     CDS             14251..15594
                     /locus_tag="VQ847_001489"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3050810.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15587..15973
                     /locus_tag="VQ847_001490"
     CDS             15587..15973
                     /locus_tag="VQ847_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3050811.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            15977..16861
                     /locus_tag="VQ847_001491"
     CDS             15977..16861
                     /locus_tag="VQ847_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3050812.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            16998..17432
                     /locus_tag="VQ847_001492"
                     /pseudo
     CDS             16998..17432
                     /locus_tag="VQ847_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17740..17910
                     /locus_tag="VQ847_001493"
                     /pseudo
     CDS             17740..17910
                     /locus_tag="VQ847_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5428 a         3446 c         4088 g         5029 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagtg gtaattgaat agaaatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctgac tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga cagctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      781 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggagccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggtt ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaaggat
     1681 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttat atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca
     2041 actacaggaa tcgaggtcga aggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2161 aacgttggcg aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgctgggatc
     2221 aaggtcatgg tggctcttcc aggagctcgt atcgctgata actacaaaat caaaaaagga
     2281 aaaatccgtg gtttggagtc acttggaatg atctgttcac ttggtgaatt gggaatttct
     2341 gactcagttg tgcctaagga attcgcagat ggcatccaaa tcttgcctga agatgccgtg
     2401 ccaggtgagg aagtcttttc ttacctagac ttggatgatg aaatcatcga actttccatc
     2461 acaccaaacc gtgcagatgc cctttctatg tgtggagtgg ctcacgaagt ggcagccatc
     2521 tatgacaagg cagtcaactt taaagaattt actctaacag aaactaatga agctgcggca
     2581 gatgcccttt ctgtcagcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     2641 gacaatgtga ccatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaagga
     2701 atccgtccca tcaataacgt agtggacgtg accaactaca tcctgctcta ttttggtcaa
     2761 ccaatgcatg cctttgactt ggataacttt gaagggactg acatccgtgt gcgtgaagcg
     2821 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     2881 ctagtcatca ctgtcgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     2941 acagaaatct ctgaaaaatc tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa
     3001 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     3061 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     3121 gaacttgcag gtgcgacggt gcgtaagggc atcgtttcag cgggtgagct tgatacttca
     3181 gatgtagaag tttcttcaac ccttgctgat gttaaccgtg tcctcggaac tgagctgtct
     3241 tatgctgatg tagaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     3301 agctttacag tcagagtccc acgtcgtcgt tgggatatca caatcgaagc tgacctcttt
     3361 gaagaaattg ctcgtatcta tggttatgac cgcttgccaa ctagtctacc aaaagacgat
     3421 ggtacagcag gtgaattgac agccacacaa aaactccgcc gtcaagttcg tactattgct
     3481 gaaggagcag gtttgacaga aatcatcacc tatactctaa caactcctga aaaagcagtt
     3541 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     3601 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     3661 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     3721 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     3781 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taagggaatc
     3841 cttgaagccc tatttactcg tttgggactc caagtaacct atacagcaac atctgaaatc
     3901 gctagccttc atccaggtcg tacagccgtg atttcactcg gtgaccaagt tcttggtttc
     3961 cttggccaag tgcatccagt cactgccaag gcttacgata ttccagaaac gtatgtggct
     4021 gagcttaacc tttcagctat cgaagctgcg cttcagccag cgactccatt tgtagaaatc
     4081 accaaattcc cggcagtcag ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat
     4141 caagaagttg tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     4201 tttgacgtct tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     4261 accttccaaa atccagaaga tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa
     4321 atccaagcat cgctcgaaga aaaagtcaat gcagaagtgc gttaaacgat agtatgatac
     4381 aaattccccc tctagtttat gaacactaga ggggtgattt tatataaaat aattaaaatg
     4441 tgatttctgt aaaaatacat ctatgatcag agttttgaaa acttacaatg tctaaatctt
     4501 taacatagta gtggttttta ggcaataaaa tatgatctat tgttgcatta aaaagttttg
     4561 gactttggct attccaagtt cctctttcaa aaggtggcag tacatttaat gcgtccctat
     4621 gagagcttat ttttgcaagt gctccatgac gcatagttgc attaaaatca cctgcaataa
     4681 tagcctttgg atattttgaa gccaattgat tatgaatgat gtttaagtct tgcttccaga
     4741 tttccattaa acctggcaga ggaggagcag tatgcaaggc aatgatatct ggtatatttt
     4801 gttttctcga atgtaataca attgtcccga accgtgttgt atgaaaagtt ttagcttctg
     4861 tatagaaacc ataacttttc ttgacaatca cagtcacagg agctattcca ctattggtag
     4921 gtggagaagt gaaaatatca tagttggcca tagaaagtcc aacttgatga aacaatagtt
     4981 tgattctctg gttttcttgc tcacctctga tattggtagc tagttcaggg aatatagcca
     5041 tatcggcgtc aaaatggcta aaaattcgct caatatgttg tgcttctatt tgattagcga
     5101 cgttccaagt tactaatttt aaggttttag tcttatttga tgcagaagaa agggttttat
     5161 ctgttccgaa taatagtaat atgagcgata gtaagagcaa aatgccagag taaaaccgta
     5221 tttgtttatt tttcttgtaa aaagatagga aaaaaaataa gaaacttaaa atagcagcca
     5281 tagttgcagt agctaagggg aaggcataaa tctgtgccaa gataggttgg gtagatagcc
     5341 aaatgttaag attagaagat gggaaaaaag aataagttat gatagggata acaaagagaa
     5401 tgaccgaaag ggcagagaga aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg
     5461 ttgctcggag ctaatgtgac tttgtgactt tacttgattg atattctttt tcttgtcttc
     5521 ctcatagatt aagtacaacc caagtaaaaa aagtccaatt taagattgaa atgattaaaa
     5581 ggcacagaga tgcaagacaa ttatactaca aaaggtaaac atttgacaat cgatagccgt
     5641 cgcttaatcg aaagatggaa aaaagaagga aaatcaaata gagaagttgc ctctctactt
     5701 ggaaaagctc ctcaaactat ccacactgaa atcaagcgtg ggacagtccg aaaatgtctt
     5761 ggaaaagggc gcttcaaaga ggtttattct gccgactacg ctcaacagtc ttatgaaaac
     5821 aatcgcaagc gctcggtcaa gaaatcaagc ttgaccaagg aactaaagga aaagattctc
     5881 cactatacat aaccaaaaat tttcgcctga aatgatggtt atggctaaag gggttaacgt
     5941 gggaatttca accatttact attggattca tcgtggaaaa ttggggttaa gcaagcagga
     6001 tctgctttat cctagaaaag gaaaatcgct taagaaatag gctagcacca actttaaacc
     6061 cgctggtcaa tctatcgaat cataattcgc tcattttttt aaaaatacat agacgtaaaa
     6121 gaaagagggt taagtgatga agaatagtgc tattgggagt aattggaagg atgtccatct
     6181 gagctcttta gcaaggagga aatccttgaa agtgatatgc gagtagctat catgagcgag
     6241 ttgattgaag ccagaaataa gcaaggaatc agtcagaaaa agctagagga actcagtgga
     6301 gtgagtcagc ctgttatagc taggatggag acaggtaaga ctagtccaca gttggacaca
     6361 gtcttaaaag tcctagctag tctaggaaag atactagcag tcgtccgact tgaacagggg
     6421 aaaagttgac tagaatcagt tatagtcttt tctaataaca agccatagtc acttataaga
     6481 attactaata acgcgtttga gcattctaac taaaatacag ctaaaaacaa gttataaaag
     6541 ggatttgagg catgtgtctc aagtcttttt cttttgtcta aaatagaggt atagtttcaa
     6601 actatatcaa agcctaattt tttacaatta tacagatgct ttcttttctg ttaagatagt
     6661 ttcaacaaca aattttggag gacacatcat gtcaactaca atcatcggtt tccctcgttt
     6721 gggcgaattc cgtgaattaa aatttacaac tgaaaaatac tttagaaaag aaatctcaga
     6781 agaagaactt ttagcagcag caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga
     6841 aaaaggcatc actgaaattc catcaaatga cttttctcac tatgataact tcctagatgc
     6901 ggctttcctt ttcaacgtgg tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga
     6961 gcgctacttc gctttgggac gtggttacca gggagaaaaa ggggacgttc gcgcccttcc
     7021 aatgaagaaa tggttcaaca ctaactacca ctacatcgtt cctaaatttg aaaaagacac
     7081 tcaagtaaaa ttggctggtc acaagatttt cgatgagttc caagaagcaa aagaacttgg
     7141 attgaacact cgtcctgttc ttgtaggtcc attcactttc cttcaattgt cagactttga
     7201 agaaggcgtg aaagcagacg acttcgtaga tagcttagtg gctgcttacc aagaagtttt
     7261 tgctaaattg gctgaacttg gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa
     7321 agacttgaca gctgaagaaa aagctctctt cttgaacctt tacaacaaac tcttggctga
     7381 caaaaaaggt cttgaagtct tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc
     7441 tgaccttgta aacttgccag tagatgctat cggtcttgac tttgttgaag gtaagaaaac
     7501 tcttgaactc gttaaaggtg gcttcccagc tgacaagact ctctatgtag gtattgtcaa
     7561 tggtaaaaac atctggcgca acaactacga aaagagcttg gctgttcttg agcaaatccc
     7621 agctgaaaac atcgttttga caagctcttg ctcacttctt catgtgccat ttacaactgc
     7681 taatgaagaa tttgaaccag cactcttgaa ccactttgcc tttgcagttg aaaaattgga
     7741 tgaaatccgt gacttggatg ctatccgcaa tggtcaaggt tcagaagctc ttgcagccaa
     7801 caaagaactc tttgcgactg agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc
     7861 tggcttgaca gacgcagact acactcgttt gccagccttt gcagaacgtg aagctatcca
     7921 agaagaagct ttcaaacttc cagctcttcc aacaacaacg attggttcat tccctcaaac
     7981 aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt gaattgtctc aaaaagagta
     8041 cgatgctttc cttgctgaaa cgattgacga atggatcaag tggcaagaag atattgactt
     8101 tgatgtcctt gttcacggtg aatttgagcg taatgacatg gttgagtact tcggtcaaaa
     8161 cttgtcagga tacttcttct ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt
     8221 aaaaccacca atcatctggg gtgatgtcac tcgtcttaac cctatcactg ttaaatggtc
     8281 tagctatgca caaagtcgta caaacaaacc tgttaaaggt atgttgactg gacctgttac
     8341 catccttaac tggtcattcc cacgtgaaga catctctatc aaggattcta ctcttcaaat
     8401 cgcccttgct atcaaggatg aagtgcttga ccttgaagct gctggtgtga aaatcatcca
     8461 aattgatgag gctgctcttc gtgaaaaatt gccactccgt cgtagtgact ggtacgaaga
     8521 ttaccttgac tgggcaattc ctgccttccg cttggtacac tcaacagtag cgtcagacac
     8581 acaaatccac actcacatgt gttactcaga atttacagat atcatcccag ctatcgataa
     8641 catggatgca gacgttattt cctttgaagc cagccgttca aaccttgaaa tcttggacga
     8701 actcaaagcg aaaaacttcc aaacagaagt gggacctggg gtttacgata tccactcacc
     8761 tcgtgtacca aacgaaggcg aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc
     8821 aagcaagaaa gtttggatca accctgactg tggtttgaaa acacgtggta tcccagaaac
     8881 aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga
     8941 ttggatttct ctccatacag tggttgttca aaaagaaatc aactagaaaa ggttattaca
     9001 tatgtcacgc caaacaccgt cactctcatt tgaagtgttc cctccaaacc cagccgtggg
     9061 taatggtaac attatttcag ccttgcagga tatgcaggag ttggctcccc attttatcag
     9121 tgtaactgcc agcaataata aatttaatat caaggaaacg acggttcgtt tggctgactt
     9181 tatccaaaat gacttggcga ttccgaccat tgcccacttg ccagctattt atctaactaa
     9241 ggacaaggtt gctgaaacta ttgttgactt ggacaaagtt ggggttcaga aaatcttggc
     9301 tcttcgtggg gatattattc cagacgtaga accacaaaag gatttccgct atgcaaccga
     9361 cttgattgag tttatcaagg aacaagcccc tcactttgat attattggag cttgctatcc
     9421 agaagagcat ccagattcgc caaatcagat ttcagatatt caaaatctta agaagaaagt
     9481 ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt gacaatgagc gcttctatga
     9541 ttttcaggac aagtgtatct tggctgggat tgatgttccc attcatgcag gaattatgcc
     9601 aattctgaat cgaaatcagg ctctccgact cttgaagact tgtgagaata tccatcttcc
     9661 acgcaaattt aaagccatct tagacaagta tgagcatgac cctgagtcgc tcagagcagc
     9721 aggacttgcc tatgcagtgg accaaatcgt ggacttggta actcaggatg ttgccggtgt
     9781 gcatctctat acgatgaata atgctgatac agcaaaatac atccatcaag caacccatgc
     9841 cttgtttaat caccagtctc taggataata aaagcaaacc attcttctca ggtgagggga
     9901 atggttcctt tttaatggta aagacctcac tttttaagaa aaatatgata aaataaattc
     9961 tgtacgtact tgatacaaag atgaaggtat taaataatac aatgcattta aactgtaaga
    10021 tttaacgaca cgagtgagtc aaatcgatgt tatttgacga gagagttagt aaagcattta
    10081 gctaatcgcc cgatagcgat tagcgtgaaa gctttagata ctttagtatt aaacctttct
    10141 aatgatgtat cttgaaaact gaacttgcct acaactctgt ggaaaaagat aaatctccct
    10201 aggagtagtc gctccgtcgt tcgatttcct atcttccttt gagttgcttg acggcttggt
    10261 atcttgagta attgaacacg gccgaaaagc tgtgtaaaaa agataaactg tcttgtcttc
    10321 atcgaagact tcgtcagttt cctattttta ctttgctttt gacgtccttg gtatcttgat
    10381 ctttgtaggc aaggcgtata atttcatcaa tcaaaagggg attaaaatgg caaaacaagt
    10441 gtttcaaacg acttttgcgg gtcgtgagtt aattgtagag actggtcagg ttgctaagca
    10501 agcaaatgga tctgttgtcg tacgttacgg tgagtcaact gtcttgactg ctgccgttat
    10561 gtctaagaaa atggcaactg gggatttctt cccactccaa gtcaactacg aagaaaaaat
    10621 gtatgcggct gggaagtttc ctggtggctt tatgaaacgt gaaggacgtc cttcaacaga
    10681 tgcgaccttg acagcgcgtt tgattgaccg tccgattcgt cctatgtttg cggaaggttt
    10741 ccgtaatgaa gtccaagtca tcaatacagt gctttcttat gatgaaaatg catctgcacc
    10801 aatggctgct atgtttggtt catctttggc actgtctatt tcagatattc catttgacgg
    10861 accaattgct ggggtacaag tgggatatgt agatggccaa atcatcatca acccaagtca
    10921 agaacaagca gagcaatctc ttcttgaatt gacagtagct ggaaccaagc acgctatcaa
    10981 catggtagag tctggtgcca aagaattgtc agaagaaatc atgttggaag cgcttcttaa
    11041 agggcacgaa gctgtcaaag aattgattac cttccaagaa gaaatcgttg ctgctgtcgg
    11101 taaagaaaaa gcagaagtgg aattgcttca cgtggatgct gaattgcaag ctgaaatcat
    11161 tgcagcctac aacagtgacc tccaaaaggc agttcaagta gaagagaaat tggcccgtga
    11221 agctgcaact caagcagtga aagaccaagt gactgccgtt tacgaagaaa aatatgcgaa
    11281 ccacgaagaa tttgaccgta ttatgcgtga tgtggctgaa atcttggaac aaatggaaca
    11341 cgcagaagtg cgacgtttaa ttacagaaga caaggtgcgt cctgatggtc gtaaggtcga
    11401 tgaaatccgt cctttggatg cggttgttga cttccttcct cgtgtacatg gttcaggtct
    11461 ctttactcgt gggcaaactc aagctctttc agtcttgacc ttggctccga tgggagaaac
    11521 tcaaatcatt gatggtttgg atccagagta caagaaacgc tttatgcacc actataactt
    11581 ccctcaatat tctgtagggg aaacaggtcg ttacggtgcg ccaggtcgtc gtgaaatcgg
    11641 tcacggtgct cttggtgagc gtgctcttgc tcaagtcttg ccaagcttgg aagaattccc
    11701 atacgctatc cgtctagtag cagaagtttt ggaatcaaac ggttcttcat ctcaagcttc
    11761 tatctgtgcg ggaactcttg cccttatggc tggtggtgtg ccaatcaagg cgccagtagc
    11821 tggtattgct atgggactta tctcagatgg aaataactac acagtattga cagatatcca
    11881 aggtttggaa gatcactttg gagatatgga cttcaaggtt gcaggtactc gtgatgggat
    11941 tacagccctt caaatggata tcaagattca agggattact gcagaaatct tgacggaggc
    12001 tcttgctcaa gccaagaaag cgcgttttga aatccttgat gtcattgaag caaccattcc
    12061 agaagttcgt ccagaattgg ctccaactgc tccgaaaatt gatacgatca agattgatgt
    12121 ggacaagatt aagattgtca tcggtaaggg tggagaaacc atcgacaaga ttatcgctga
    12181 aacaggtgtt aagattgata tagacgaaga aggaaatgtg tctatctact ctagtgacca
    12241 agatgctatt aaccgtgcca aagaaattat tgctggtttg gttcgtgaag ccaaagtgga
    12301 tgaagtttac cgtgctaaag tcgttcgtat cgagaaattt ggtgcctttg ttaacctctt
    12361 tgataagaca gatgcccttg ttcatatctc tgagatggct tggactcgta ccaatcgtgt
    12421 agaggatttg gtagaaatcg gggatgaagt tgatgttaag gttatcaaga ttgatgaaaa
    12481 aggccgtatc gatgcctcta tgaaggctct tctacctcgt ccgccaaaac ctgagcatga
    12541 tgaaaaaggt gaaaagtctg agcgccctca ccgcccacgt catcaaaagg atcacaaacc
    12601 taagaaagaa tttacagaaa caccaaaaga ttcagaataa gaaaaggaga aatgtatggg
    12661 gtggtggcgc gaaaccattg atattgtaaa agaaaatgat ccagcggccc gcaccacttt
    12721 ggaggttttg ctgacttatc caggtgtcaa ggccttggcg gcccaccgtc tctcgcattt
    12781 tctctggaag cacggcttca aactattagc tcgtatgtac agtcagtttt ggcgcttttg
    12841 gactcagatt gagattcatc caggagccca gattgattca ggtgttttta ttgaccatgg
    12901 ttctggtctg gtgattggag agacagcgat tgttgaaaaa ggcgttcttc tctatcacgg
    12961 agtgactctc gggggaacag ggaaagactg tggcaaacgc catccgactg tacgaaaggg
    13021 agccctcata tcagcccatg cccaagttat cgggcctgtg gaaattggtg aaaatgccaa
    13081 ggtcggtgct gcagcagttg tcgtagcaga tgtacctagt gacgtgacgg ttgtcggtat
    13141 tccggccaag attgtccgtc ttcatggtaa gaaagatgag cctgtcattc acgaagtcga
    13201 agaaaaacga gagtattatg tcaataaact cgagcaggct aaagatgcca gtcacagatc
    13261 gtctggtttg tagaggatac ctatatgatt caagcaagaa acaagttaag ccaagaggag
    13321 ctatctgaag cgaaaaaagt aattaactgt tgccaaaact atgacggtac ctatcgcgat
    13381 ccctatctct ctaacatgct taattttgac ccaaacatgc ccgccttttt cctttattat
    13441 gaaaaaggcg aacttgttgg tttattaact gtctatgcag atgaccaaga tgtagaagta
    13501 acgatactgg ttcatccagg tcatcgccgt caggggattg cgcgtgcatt gtttactagt
    13561 tttgagagag aaatagcttc tttccccatt cggtcagtca cttttcagac agaacgtatt
    13621 tttttagaga atcatcctga ctttgccagt aactggggac taatcgagga tgaagagaca
    13681 gaaacttggt taggtaagga tagaagacct tatccgttag caaatgtttc ccatcttgaa
    13741 gttttgttag cagatagttc gtatcaggat caaattagtc aattaaaatt tcaggcattt
    13801 tcagaggaac atgaatcgag agaagttgtg gatagatatg tcgctgaagc tctgaaggat
    13861 ccagaaagtc gcttatatat tttattaaaa gacggtcagg ttattgggac ttgtacggtt
    13921 gatttatcga ctaatacgaa ttacttctac ggtttagcaa tattggaacc tgaacgtgga
    13981 aaaggctatg gaagctactt agcaaaatcc ctcgtcaacc aactaattga gcaaaatgac
    14041 aaggaatttc agattgcagt ggaagatagc aatgtaggtg ccaaacgttt gtatgaaaaa
    14101 attggctttg tcaaacagac tcaggtggtt tatctgaatg agaaaggagc aagggattcc
    14161 gaagtgtaga gatattcgga ctgaaattta cttgaacttt tagtgatgaa actaattgtt
    14221 cttggatttc agctttcctg attatgattt atgattaaaa tctatgacac catgtctcgt
    14281 gatttgcgag aatttgtccc gattgaggac ggcaagatca agatgtatgt ttgtgggcca
    14341 acggtgtaca actatatcca cgtgggaaac gcccgttcga cggtagcttt tgatacgatt
    14401 cgtcgctatt ttgagtaccg tgggtataag gttgcctata tttccaattt tacagatgtg
    14461 gatgataaga ttatcaaccg tgccagggaa gaaggcatca cgcctcagga ggttgcggat
    14521 aagtacatcg ctgcctttcg tgaggatgtg acggccttgg gcgtgaaacc tgcgactcgc
    14581 catccgcgtg tagtggagtt tatggcagac atcatccgtt ttgtggaaga cttgatcgag
    14641 aaaggctttg cctatgagag tcaaggggat gtctatttcc gtgtagaaaa atcccacaac
    14701 tatgctaaat tggctaataa aaccttggaa gatttggagc taggtgcttc aggtcgtacc
    14761 gatgaagaaa cggctcgtaa ggaaaatcct gtagactttg ctctatggaa atcttccaaa
    14821 ccaggtgaga tttcttggga tagtccttgg ggacctggac gtccgggttg gcatattgag
    14881 tgttcagtca tgtcgacaga gattttaggt gataccattg atatccacgg tggtggagct
    14941 gacctagagt ttccacacca caccaatgaa attgcccaat ctgaagctaa aacaggcaag
    15001 gcttttgcta actactggat gcacaatggc tttgtcaata tcgacaatgt caaaatgtct
    15061 aagtccttgg gtaacttcat tacggtacac gatgccctta aaactcttga tgggcaagta
    15121 cttcgtttct tctttgcgac ccagcactac cgtaagccta tcaacttcac ggaaaaggca
    15181 gttcgcgatg ccgagaccaa tctcaagtat ctgaagaata cttacgaaca accatttaca
    15241 ggaaacgtgg atgcccaaga gttacaaaac tttaaagata agtttgtagc agctatggat
    15301 gaagatttta atgctgccaa cggtatcaca gttgtctttg aaatggccaa atggatcaac
    15361 tcagggaact atgatgcaag tgtcaagcaa gctcttgcag atatgttaga aatttttgga
    15421 attgtctttg ttgaggaagt tttggatgca gagattgaag acttgattca aaaacgccaa
    15481 gaggcgcgtg ccaatcgaga ctttgagaca gcagaccaaa tccgtgacca attggttact
    15541 caaggaatta agctccttga taccaaggat ggagtgaggt ggacacgtga ttgatgtcaa
    15601 tctcattaac gggattgcgc tagcctttga gggggatgcg gtgtattcta tgtatattcg
    15661 ccgtcacctc atcctcaaag gtatgaccaa acccaataaa ctccatcaag aagcaaccaa
    15721 gtatgtgtca gccaaggctc aggctcgcct gattgctctc atgttggagg agcaggtcct
    15781 aacggaaaaa gaagaagaaa tctacaaacg tggccgcaat accaatagcc acacaaaggc
    15841 taaaaatgca gatgtcgtga cttatcgtat gtccacggga tttgaagcgg ttatgggcta
    15901 tctccatatg actgagaatc tggaacgtct tgagagtttg gtttcatggt gcatccaaaa
    15961 agtggagggc tagaacatga gggaaaaaga actacaagac tggtttcctg aggctcggat
    16021 ttcagaccaa ccagtagaga aagagggcta tctcacgctc cctttagctt ctcagcagtg
    16081 gattttgctg gaggaagctg ggctcagcga gcgtgaaaag cagttggttg cccttttgac
    16141 ccagcaggag caggctcgtt cgctaaaccc ttggtattcc tatctggttg aaggcaaggg
    16201 acaggcaccg caagttttta aaaagattca gttggtttat tgccatcttt cttattttca
    16261 gcaggaaaat ctggcttctt ggctagatat gatgcggact ctttttccga attgtcagac
    16321 agtgctacag gtcggatctc aggattatgt tttcgtgctt caacaagaca aatacactta
    16381 tgtaagagat attttaagtg atacgattga agcggttgag tatgactttg gacttcgtct
    16441 ttctatcatg ttgggtcagg tttggtctca gacgggacat caagccctat cagacttaat
    16501 caaagctgag cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag gtgttcatac
    16561 tttttctcag ctctatcttt ggagtatggg agaaagactc gtggacttga agccaatcaa
    16621 ggaatgtcta caccagatga ttttggatca agatcagatt caggaaatca ttctctctct
    16681 ttgggaaaat agtgctgttc tcactaaaac agcccagcaa ctctatctgc accgcaattc
    16741 tctccaatac aagattgata aatgggaaga gttgacaggg cttcagttga aagagttgac
    16801 cgacctgacc ttgtgttatc aattgatttt aggttctttg tcaactatag ttggtttgta
    16861 aagaagttaa tatttggaga agaggatggc catcttctcc atttttatgt gcagagttat
    16921 agtggcttga tgctgggaaa gtacactgtg actgctaaaa cattcctaga agttgctttg
    16981 atttccctaa tctatttatg tgaattttat gttattttac tataacagtt gttgctaagc
    17041 taaataatag tggggaagtt tatttagacg taagcattga agataatcag ggaggtagtg
    17101 ggtataattt cagttctgtt tcaagtagct cacaaacagc taaatatgaa ggaactggtt
    17161 ataataacaa ttcatcatta tatataacga ttgataaaac gtctgatgca acagctcttt
    17221 tgaaattaaa gttgaataat gttgataatc aacctgctac tgaagttcct agttcaggaa
    17281 ttactgtaaa attaaatgct aaagataatg ctggaaactg gacaagtgct tcgaataaaa
    17341 aagaagtaac agtaaaaatt gtttctgcta aaccgacata tccagacaaa attttagtga
    17401 aaaatcctga taatataaaa gatacagaaa aaaatgccat tattgaaaaa ttgaaagagg
    17461 caaataaaaa tcatccagca ggagctccaa cctttgctaa aggtgaagga gagcatgcaa
    17521 atgatattgt agcaacttat tcagatggta caacttatta tgtaccgtta aatgatgtga
    17581 caaaatatgc gaggtagtgg ctgtaccact cacttattca cctccccgtg atttgtagta
    17641 gtgataggct ttctcactat tattataaaa caaaataaag atcacaacac tttttcattc
    17701 tgtgttgtgc cttgagtgaa acgaaaggaa tgaattataa atatgaaaag tatagtcact
    17761 aacatagatg agcgcttgcg tactcgccta cgagtgatta tctggaagca atggaagaag
    17821 aaatcgagac gattatgggg attgcttaag ttaggggttc ctaaatggat agcagataag
    17881 gtatctggct ggggcgagca ctatcaatta tattaaaatg aaataagaat aggacgaatc
    17941 gatcagggaa gtcaaatcga tttctaacaa tattttagaa gtagaggtat a
//
LOCUS       DAVBNN010000043        16835 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBNN010000043 DAVBNN010000000
VERSION     DAVBNN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.043"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            49..537
                     /locus_tag="VQ847_001494"
     CDS             49..537
                     /locus_tag="VQ847_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3050813.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            534..1721
                     /locus_tag="VQ847_001495"
     CDS             534..1721
                     /locus_tag="VQ847_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3050814.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            1714..2079
                     /locus_tag="VQ847_001496"
     CDS             1714..2079
                     /locus_tag="VQ847_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3050815.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            2095..3441
                     /gene="asnS"
                     /locus_tag="VQ847_001497"
     CDS             2095..3441
                     /gene="asnS"
                     /locus_tag="VQ847_001497"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3050816.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMERTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            3594..3884
                     /locus_tag="VQ847_001498"
     CDS             3594..3884
                     /locus_tag="VQ847_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3050817.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            3896..4366
                     /gene="ssbA"
                     /locus_tag="VQ847_001499"
     CDS             3896..4366
                     /gene="ssbA"
                     /locus_tag="VQ847_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3050818.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            4398..4637
                     /locus_tag="VQ847_001500"
     CDS             4398..4637
                     /locus_tag="VQ847_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3050819.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            4932..6332
                     /locus_tag="VQ847_001501"
     CDS             4932..6332
                     /locus_tag="VQ847_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3050820.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            6334..6693
                     /locus_tag="VQ847_001502"
     CDS             6334..6693
                     /locus_tag="VQ847_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3050821.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            6747..7496
                     /locus_tag="VQ847_001503"
     CDS             6747..7496
                     /locus_tag="VQ847_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3050822.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            7486..7785
                     /locus_tag="VQ847_001504"
     CDS             7486..7785
                     /locus_tag="VQ847_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3050823.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            7856..8791
                     /locus_tag="VQ847_001505"
     CDS             7856..8791
                     /locus_tag="VQ847_001505"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3050824.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            8877..9389
                     /locus_tag="VQ847_001506"
     CDS             8877..9389
                     /locus_tag="VQ847_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3050825.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            9426..10021
                     /locus_tag="VQ847_001507"
                     /pseudo
     CDS             9426..10021
                     /locus_tag="VQ847_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            10122..10316
                     /locus_tag="VQ847_001508"
     CDS             10122..10316
                     /locus_tag="VQ847_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3050826.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(10362..11807)
                     /locus_tag="VQ847_001509"
     CDS             complement(10362..11807)
                     /locus_tag="VQ847_001509"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3050827.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            11913..13535
                     /locus_tag="VQ847_001510"
     CDS             11913..13535
                     /locus_tag="VQ847_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3050828.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            13738..15696
                     /locus_tag="VQ847_001511"
     CDS             13738..15696
                     /locus_tag="VQ847_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3050829.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            15868..16428
                     /locus_tag="VQ847_001512"
     CDS             15868..16428
                     /locus_tag="VQ847_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050830.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            16429..16803
                     /locus_tag="VQ847_001513"
     CDS             16429..16803
                     /locus_tag="VQ847_001513"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050831.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT         4992 a         3092 c         3753 g         4998 t
ORIGIN      
        1 ttcttatatt cacttgtaat aaagcttaat agatggtaaa atagacgagt gaaaaaaaga
       61 caaaacaaag caaaaaataa tctactgtgg cagtatggtc tagggatgac gattttgttt
      121 gtggttatca gtgcttcctt tctgtatatg gtttctctta gcatgaaacc ctatcaaaca
      181 gctaaaagtg aaggagaaaa attagctcag cagtatgcag gattagagca ggccgatcag
      241 gttgatttat acaatggctt ggaatcttat tacagcgttc ttggtcgtaa taaacagcaa
      301 gaagcacttg ctgttctgat tggaaaagat gatcataaga tttacgttta tcagctaaat
      361 cagggtgttt cacaagaaaa agcagaaacg gtttctaagg aaaagggagc tggcgaaatt
      421 gacaagatta tctttggtcg ttatcaagat aagccaatct gggaagtcaa gtcaggatct
      481 gatttttatc tagtagattt tgaaacagga gcattggtca acaaggaggg cctatgaaat
      541 tatccaaccg tgttttagaa atggaagaaa gtgtgacttt ggctgctgga gcccgtgcca
      601 aagcactgaa ggctgagggc agagatattt tgtctctaac cttgggtgag ccagatttca
      661 ctactcccaa aaatatccaa gatgccgcca ttgcatcgat tcgagatggg cgtgcttctt
      721 tttatacagt aacctcaggt ctgccagagc ttaaggcggc ggtcaatagc tactttgagc
      781 gcttttacgg ctattctgta gcgtcaaatc aagtgacagt cgctgcggga gccaaatatt
      841 ctctctatac cttctttatg gctgtggtca atccaggtga tgaagtcatc atcccaaccc
      901 catactgggt tagctatgga gatcaggtca agatggcaga aggcgttccc gtctttgttt
      961 ctactaagga agacaatcac tttaaggtga ccgtagatca gttagaagca gctcgcactg
     1021 acaagaccaa ggttttggtg ctgaattcgc catctaatcc cacaggtatg atttacaccc
     1081 gtgaggaact cttggcaatt ggaaactggg ctgtagaaaa tgatattctc atcctagcag
     1141 atgatatcta tggccgcttg gtttataatg gtcatgagtt cacaccgatt tctagcctat
     1201 cggaagcgat tcgcaagcaa acagtggtca tcaatggtgt gtctaaaacc tatgccatga
     1261 ctggttggcg gattggttat gccgttggag aagcagacat tatcgctgcc atgtccaaga
     1321 ttgcaggtca aacaacttcg aatccgtcag cagtagccca atatgcagca gttgaggctc
     1381 tatcaggtga gcaagatact gtagaaagca tgcgtcaggc ctttgaggaa cgtcttaata
     1441 ctatctatcc cctccttgca gaggtgccag gatttgaagt ggtcaaaccg caaggggcct
     1501 tctatctctt cccaaatgtc aaaaaggcca tggagatgaa aggctacacg gatgtgacag
     1561 actttacaac tgctatctta gaagaagccg aagtggcctt ggtaacagga gctggatttg
     1621 gagcaccaga aaatgtccgc ctcagctatg cgacagacct agacacgctt aaagaagcag
     1681 tcgaacgctt gaaagcattt atgggtagtg agaatgattg atcattttga gattaaggta
     1741 aaggatttac aaatttcaga aggattttat aggagttttc tcgctccttt ggactataaa
     1801 atggctttta agactagttc tctaattagt tttctatccc cgaacagccc tcatcctggt
     1861 ggtgattttt ggctgactca gggaacacaa gatcctgttc attttgcttt tttagcagaa
     1921 aataaggaag aagttcaggc ttgttatgag gctggcttag aggcaggtgg gcgagacaat
     1981 ggggttcctg gttatcgaag tgagcatccg atttattatg ctgcttttat gattgacctg
     2041 gatgggaaca atatagaggt ggtttgccat aaagaataaa aaagaaaagg aaaaataatg
     2101 acaaaacgtg taacgattat tgatgtaaaa gactatattg gtcaagaagt gacgattggc
     2161 gcttgggttg ccaacaaatc aggaaaaggg aaaatcgctt tcttacaatt gcgtgatgga
     2221 acagccttct ttcaaggtgt ggcttttaaa ccaaactttg tcgaaaaatt tggtgaagaa
     2281 gtgggacttg agaagtttga tgttatcaaa cgcttgagcc aagaaacgtc tgtttatgtg
     2341 acaggtattg tcaaagagga cgaacgttct aaatttggct atgagttgga catcacagac
     2401 atcgaagtga tcggtgaatc tcaagactac ccaatcacac caaaagaaca cggaacagac
     2461 tttttgatgg ataaccgtca cttgtggcta cgctctcgta agcaagtagc tgtgttgcaa
     2521 atccgtaacg ctattatcta tgcaacttat gagttctttg acaagaacgg ttttatgaag
     2581 tttgacagcc caattctttc aggaaatgcg gcagaagatt ctacagaact ctttgaaact
     2641 gactacttcg gaacgccagc ctacttgagc caatcaggtc aactttacct agaagcaggg
     2701 gctatggctc ttggtcgtgt ctttgacttt ggtccagttt tccgtgctga aaaatcaaaa
     2761 acacgccgtc acttgactga gttctggatg atggatgctg agtactcata cttgacacat
     2821 gatgagtcgc ttgacttgca agaagcttat gtgaaagctc ttctacaagg tgttcttgac
     2881 cgcgcgcctc aagccttgga aaccttggaa cgtgatacag aactcttgaa acgctacatt
     2941 gcagagccat tcaaacgtat cacttacgat caagccattg acctcttgca agagcatgaa
     3001 aatgatgaag atgctgacta cgagcatctt gagcatggtg atgactttgg gtcaccacac
     3061 gaaacttgga tttcaaacca ctttggtgtg ccaacatttg tcatgaacta tccagcagcc
     3121 atcaaggctt tctacatgaa accagttcct ggaaatccag agcgcgtgct ttgtgcagac
     3181 ttgcttgctc cagaaggcta tggagaaatt atcggtgggt ctatgcgtga ggaagattac
     3241 gatgcccttg tcgctaagat ggatgaactt ggcatggaac gtacagaata tgaattctac
     3301 cttgaccttc gtaaatacgg tacagttcca cacggaggat ttggtatcgg tatcgaacgt
     3361 atggtaacct tcgcagcagg aacaaaacat atccgtgaag ctattccatt cccacgtatg
     3421 ttgcaccgta tcaaaccata agaacaggaa aacgcccatg tggcgttttt tcgaattcta
     3481 gtgtttttac ttgcgtaaaa aaattttttc tagtataata gtttattgtg agcgaacctc
     3541 acttacccct tgcaaagtct tggggtcatt agaccaaaag gaggaacata tcaatggcta
     3601 aatacgaaat tctttatatc attcgtccaa acattgaaga agaagctaaa aacgctttgg
     3661 tagcacgttt tgactctatt ttgactgaca acggtgcaac tgttgttgaa tcaaaaactt
     3721 gggaaaaacg tcgtcttgca tacgaaatcc aagatttccg tgaaggactt taccacatcg
     3781 ttaacgttga agcaaatgac gatgcagctc ttaaagagtt tgaccgtctt tcaaaaatca
     3841 acgctgacat tcttcgtcac atgatcgtca aaattgacgc gtaagaaggt aaactatgat
     3901 taacaatgtt gtacttgtag ggcgtatgac acgtgacgct gagttgcgtt ataccccatc
     3961 aaatgtagca gttgcgactt ttactcttgc agtaaaccgt acatttaaga gtcaaaatgg
     4021 tgaacgtgag gctgatttta tcaatgtcgt tatgtggcgc caacaggctg aaaatcttgc
     4081 taactgggct aaaaaaggct cacttatcgg ggtgacaggt cgtatccaga ctcgtagtta
     4141 cgataaccag caaggacaac gtgtctacgt gacagaggtc gtggctgaga atttccaaat
     4201 gttggaaagc cgtagtgtgc gtgagggtca cacaggtgga gcttactctg caccaactgc
     4261 aaactattca gcacctacaa attcagtacc agacttttca cgtaatgaaa atccatttgg
     4321 agcaacaaac ccattggata tttcagatga tgatttacca ttctaatgga caactaaact
     4381 tataaaggag aaaaaacatg gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag
     4441 ttgattacat cgcagcaaac aaaattgaat atgttgatta caaagatact gagcttctta
     4501 gccgtttcgt ttcagaacgt gggaaaatcc ttcctcgtcg tgtaacagga acttcagcta
     4561 aaaaccaacg taaagtaaca acagctatca aacgcgctcg cgtaatggct ttgatgcctt
     4621 tcgtaaacga agattaaaga aaagacccgg ttgggtctct ttttcatgag cttgaaaaca
     4681 agaaagcgaa ttaagacccc aacgggtctt ttttcacaag ctttgaaatg agagagcgag
     4741 ttaggctcag tggcttcctt tttacgagtt tgaaaacaag agaacacatt aaaagcacga
     4801 tggagctttt tcataaatat gtctcttttc tcatccaaga aattaaaata aaaatgataa
     4861 actttttgaa aataggggat ttgcctactt tatgatataa tggaaagagt tagattgaaa
     4921 gaggtagtga gatggacgcg aaattaagat acaaggcaaa gaagatcaag attgtctttt
     4981 ttgatattga tgatacattg cggaattcaa agacagggtt tattccaact acaattccca
     5041 ctgtttttaa acagttgcgt gaaaaaggaa ttttaacagg aatcgcctct ggacgtggca
     5101 tttttggtgt tgttccagag attcgtgatc tcaagcctga cttttttgta actttgaatg
     5161 gggcttatat cgaagataaa aaaggtcagg tcatttatca gcatcagatt gaaaagtcag
     5221 atgttgagga gtatatctct tgggctaagc aagaaggaat tgagtatggc ttggttggga
     5281 gtcatgatgc caagttgtcg actcgcaccg atatgatgag tgaagctatc aatccaattt
     5341 atcccgactt agatgtagat cccgatttcc atgaaaaaga agatatctat cagatgtgga
     5401 cttttgaaga taagggagat gacttgcact tgcctgacag tctctcagac aaacttcgca
     5461 tggttcgttg gcatcaacat tcgtctgata ttgtgccgat ttcaggctcc aaagcgacgg
     5521 gggtggaaaa ggttgtggaa caccttggct tgaaaccaga gaaggtcatg gtttttggag
     5581 atggtctcaa tgacttggaa ctctttgatt atgctggaat cagcgttgcc atgggaattt
     5641 ctcatgataa aatcaaagaa aaagcagatt atattacaaa aacattagaa gaagatggca
     5701 tttttgatgc cttagaagta tttggtatgg tagaaaaaga attgcatttt ccacaagtag
     5761 acattgaaac agtagaaggt cttcttgcga ctattaagac caatcacgga gacttacgta
     5821 tcaagctttt ccctgaacat gctcctaaaa cagtggctaa ctttgtatct ctttcaaaag
     5881 atggctacta tgatggtgtc attttccacc gtattatcaa ggactttatg atccaaggtg
     5941 gagacccaac tggaactggt atgggtggcg agtcaatcta cggcgaatct tttgaggatg
     6001 aattctcaga agagctttac aatatccgtg gtgctctttc catggcaaat gctggtccaa
     6061 ataccaacgg cagccagttc tttatcgtgc aaaaccaaca cctaccttat tcgaagaaag
     6121 aaattactcg tggtggttgg ccagaaccga ttgcagaaat ctatgccaat caaggtggga
     6181 cacctcacct agaccgccgt cacacggttt ttggtcagtt agctgatgaa gcatcttacg
     6241 ctgtcttgga tgccattgct gctgttgaga caggagctat ggacaagcca gttgaagatg
     6301 ttgtaattga aactattgaa atcgaggact aagatgaaaa tcggtgataa gctaaagggg
     6361 cgtattacag ggattcagcc ctacggtgcc tttgttgagt tagagacggg tgatacgggg
     6421 ctgattcaca tttcagaaat tcggacagga tttattgaaa atattcatga aaccttgaaa
     6481 gtcgatgaag aggttcaagt tcaggtagtg gatttagatg aatttacggg gaaagccagt
     6541 ctttctatcc gcactttgga ggaagaaaag taccagtttc ctagacggag acgcttttca
     6601 agtgaccgct ttaactacgg ttttgctccc tttcgacgaa tgctaccaat ctggactgga
     6661 gaagctctgc accatttaaa aaagaagaag tagtttagag ttttatattt tttgtaatgt
     6721 taatataaat ttattataat aggaccatgg aagaagaaca attattaaaa tcaggagagc
     6781 gcattaacca gctcttttcg acagatatca aaatcattca aaatagagag gtttttagct
     6841 attcggtgga tagtgttctc ttatcacgat ttccacgttt tcctaagaag gggttgattg
     6901 tggatttctg tgctgggaat ggagcagtgg ggctttttgc tagcactcgt actcaagcac
     6961 agatattgtc tgttgagatt caggagcgtt tggcggatat ggctgaacgc tctgtccgtt
     7021 tgaatggatt agaggagcaa atgcaggtca tctgcgatga tttgaaaaat atgcctgctc
     7081 acattcaggg gagtaaggta gatatgattt tgtgtaatcc accctatttc aaggtggatc
     7141 cttattctaa tctgaacgag agtgaacatt atctcttggc tcgacacgaa atcacgacta
     7201 atttggaaga aatctgtcgt agtgcccaga gtattctcaa gtctaatggg cgtttggcca
     7261 tggttcatcg tcctgatcga cttctggata ttttggatac gttaaaacga cataatctag
     7321 cccctaagcg cctgcagttt gtttatccaa aaagagaaaa ggaagccaat atgcttttga
     7381 ttgaggcgat caaggatggc tcaacaagtg gctttaaggt cttacctcct ttgattgtcc
     7441 acaatgatga tggctcttat acgcccgaaa tcgaagagat ttattatgga tcataaggct
     7501 tatatgtacg ttctggagtg tcgtgatgga tcctactata taggctatac gactgatgtg
     7561 agaagacgcc tcgctatcca caatagtggg aagggagcca aatatacacg agcacgcttg
     7621 ccagtcaaac ttatctatgc tcaaggtttt gccagtaagg aagaagccat gtcggctgaa
     7681 gctcttctca agcgtaagaa gaggccacag aaggaagaat ttttatctga aaatcaagat
     7741 agaaatttac tcagttattt tgaagaatcg tggggagtcc tttgactcct cttacctttg
     7801 tcaaaaagcg aaaaaaatgc tacaataaag aaaataaaca aaatgaggta ttatcatgtc
     7861 caagattcta gtatttggtc accaaaatcc agactcagat gccatcgggt catctgtagc
     7921 ttttgcctac cttgcaaaag aagcttacgg tttggatacg gaagctgttg cccttggaac
     7981 tccaaatgaa gaaacagcct ttgtcttgaa ctattttggt gtggaagcac cacgtgttat
     8041 cacttctgcc aaagcagagg gggcagagca agttatcttg actgaccaca atgaattcca
     8101 acaatctgta tcagatatcg ctgaagtaga agtttacggt gttgtagacc accaccgtgt
     8161 ggctaacttt gaaactgcaa gcccacttta catgcgtttg gagccagttg gatcagcgtc
     8221 ttcaatcgtt taccgtatgt tcaaagaaca tggtgtagct gtgcctaaag agattgcagg
     8281 tttgatgctt tcaggtttga tttcagatac ccttcttttg aaatcaccaa caacacaccc
     8341 aacagataaa atcattgctc ctgaattggc tgaattggct ggtgtgaact tggaagaata
     8401 tggtttggca atgttgaaag ctggtaccaa cttggctagc aaatctgctg aagaattgat
     8461 tgatatcgat gctaagactt ttgaactcaa cggaaataat gtccgtgttg cccaagtgaa
     8521 cacagttgac atcgctgaag ttttggaacg ccaagcagaa attgaagctg caatgcaagc
     8581 tgcaaacgaa tcaaacggct actctgactt tgtcttgatg attacagata tcgtcaactc
     8641 aaactcagaa atcttggctc ttggtgccaa tatggacaag gtcgaagcgg ctttcaactt
     8701 caaacttgaa aacaatcatg ccttccttgc tggtgccgtt tcacgtaaga aacaagtggt
     8761 acctcaattg actgaaagct ttaatgcgta agattttggg tgtcagctca aaatcggaaa
     8821 gtctagtttg ccttatatcg aaaggagttt cggctccttt tttctaggag tgaagtatgt
     8881 tagaaaatgg cgatttgatt tttgtgagag atgggtcaga catgggacag gccatccaga
     8941 cttccacagg taactatagc catgttgcca tttatttgga tgggatgatt tatcatgcta
     9001 gtggacaggc tggtgttgtc tgtcaagaac cggcagactt ctttgagtcc aatcatttgt
     9061 acgacctcta tgtttaccca gaaatggata tccagtcggt gaaggaaaga gcttgcagac
     9121 atcttggagc accctacaat gcttctttct atccagatgc agctggtttc tactgctccc
     9181 agtatatagc agaaatccta cctatttttg aaactattcc tatgaaattt ggagatgggg
     9241 aacaggagat tagtgatttt tggagggagt attacataga actaggtctg cctgttcctc
     9301 tgaaccaagc tgggaccaat cctagtcagt tggcagcatc gcctctgtta caatgtaaag
     9361 aaaggaatct tcatgattca gatttttaat ccatctcgtt tgacgagaca gccatttttg
     9421 gagaattgat ccgctatctg gaccagtatg aggatgtgat tctacgggaa attaaggctc
     9481 aatttccaga tgttgcagtt gataaactca tggaagagta tataaaggca agcttgattc
     9541 tacgtgaaaa taagcgctat tacctcaatt ttcctacgct tgaatcactt gatagtcttg
     9601 aactggatca agagattttt gtcagagaag ctagtccggt ctatcaagcc ttgttggagc
     9661 agagttttga gacggaattg cgcaatcaaa tcaatgcagc tattttagtt gaaagacgga
     9721 ctttgcgcgc attaaaatga ccctgtccaa ttatttttac aaggtcaaac agcagtatcc
     9781 tttgacagaa aaacagcagg agctctatga cattttagga gatgttaatc ctgagtatgc
     9841 actcaagtat atgacggctt ttttgttgaa atttctcaaa aaagaccagc ttatgcagaa
     9901 atgccgtgat atctttgtgg acagtttggt tgtcttaggc tatattgtgc aaaatgaaga
     9961 tagaaagtat gagttggcta tcgattttga taaggagaga ttaactttct acttagcgtg
    10021 atttcttgtt tctgagcaca ttgtttgact ttccttagta ttcggtataa actatatgta
    10081 accggtaaca catatcggaa taaactaaag gagacaatca tatgtcactt gaaaacaaat
    10141 tggaacaagc aacaggcgct gtcaaagaag gttttggtaa agttactgga gacagcaaga
    10201 cagaacttga aggagctgtt gaaaaaacag ttgctaaggc aaaagacgtt gtagaagacg
    10261 caaaaggtgc tgtagaaggt gccgttgaag gtttgaaaaa cgtttttact aaataatagg
    10321 aaaaaatcaa gggtttcatt ttcccttgat tttttctatt cttataaata attttctgcg
    10381 acggctgtat ctcctgggta ggattctttc ttgccctgga tgatttggta acaatcggct
    10441 cccttacccg caataataac tgcatctaat tcgtgatttg tgatagccat tgccgccttg
    10501 atggcttctt ggcgatccgc aatcttttca acaggatgat tgatgtagct actaatttca
    10561 tctgcaatgg ccattgggtc ttcatagtta gggtcatcag cagtcagaaa gacttgaatc
    10621 tcagggtgtt gattgaggag gaggccaaag tccttacgac gactttctcc cttgtttcct
    10681 gttgatccca gaaccagagc aatctttccg gtttgatgag tttcaaccac attgatgagt
    10741 tttttcagac tatccccatt gtgggcatag tcgatgaaga ccttggctcc atttttctga
    10801 gtgaggactt ccatacgacc aggaacgcgg gttgcagcga tgcctttttt gatgtcctca
    10861 agacttgctc cgagacggag acaagcaagt ccagcagcaa ctgcattttc ttggttgaag
    10921 ttgccaatga gttggatatc ataatctcca gcgagtttac ccgtagctga aaagctaaag
    10981 gctttggaat tctcgatttg gttatcaaat tggctaccat agaaatcatg gtcttgatct
    11041 tcaacctgtt ctttcaagac tgagaagtgg tccatgtcac tgttaatgat gactgctcgg
    11101 ctattttcca tcaagagacg cttgtggtag aaatagtctt caaagctaga gtgttcaatc
    11161 gggccgatat ggtcaggagt gatgttaaga aagactccta catcaaaggt cagtccatag
    11221 actcgatgga ctagataggc ttgactggag acttccatga tgaggtgggt acggtcattt
    11281 tgcacagcct gattcatcat gtcaaagagg tcaatactct caggggttgt caacgctgac
    11341 ttaaaaaaag tctcgccatc aagagttgtg ttcatggtcg acaacatagc aggtctatgc
    11401 ccttgagata agatgttata ggcgaaatag gttgctgttg tcttaccctt agtaccagta
    11461 aaggcaagga gtttgagttt ctcttgtgga ttaccataga actccatggc aatcaaactc
    11521 atggctttct ttatatcgtt cacaatgatg acagggatat cgacttcgta gtccttttca
    11581 gctacatacc aagctaaacc ttgtgttata gcagaaagaa ggtattcttt tttaaaggca
    11641 gcgccttttg caaaaaaaag agtgtcttct gttacttttc ggctgtcgta gctgatgcta
    11701 tcaaaaataa ctttgctgta gttgtagtgg taatgacctt ggtcaataat ttcgcgaaaa
    11761 aggccatctt tctttaaaat atctaatacg gtttcaatct taatcatact ttctattgta
    11821 aaccgaaagt cgtaaattta caagtaacaa ggaaaagttt ataatggaag ataaggagtt
    11881 tttcctagtt atcaaaattg aatgaggaat ctatgtcgca cgaaaacaat caccagcagg
    11941 cccagatgtt acgggggact gcttggctaa cggctagtaa ctttatcagt cgcctactcg
    12001 gggctgttta cattatccct tggtacatct ggatgggggc ttatgcagct aaggcaaatg
    12061 gtctctttac catgggttac aatatctatg cttggttctt gttggtttca acagcgggga
    12121 ttccagttgc ggtggccaag caagttgcca agtataatac catgcgagaa gaagagcata
    12181 gctttgccct gattcggagc ttcttaggct ttatgacagg actaggtctg gtttttgctt
    12241 tagtcttgta tgtctttgct ccttggctag cagacttgtc tggcgtgggc aaagacttga
    12301 tcccaatcat gcaaagcttg gcttggggag tcttgatttt cccgtctatg agtgttatcc
    12361 gaggattttt ccaagggatg aataacctca aaccctatgc tatgagccaa attgctgagc
    12421 aggtcattcg tgttatctgg atgctcctag caacctttat cattatgaag ctcggttcag
    12481 gagattatct agcagccgtt acccaatcaa cctttgctgc ctttgtcggt atggtagcca
    12541 gttttgcagt cttgatttat ttccttgccc aagaaggttc actcaaaaga gtctttgaaa
    12601 caggagataa gattaacagt aagcgtctct tggttgatac cattaaggaa gccattcctt
    12661 ttatcctgac agggtctgcc atccagctct tccagatttt ggatcagctg acctttatca
    12721 atagtatgag ctggtttacc aactacagca atgaggactt ggttgtcatg ttttcttatt
    12781 tctcagccaa tcctaataaa atcacgatga ttttgatttc tgtaggggtt tcgattggga
    12841 gtgttggttt gccacttttg acggaaaact atgtcaaggg ggacttgaaa gcagcttctc
    12901 gtctcgttca ggacagtctc accctactct ttatgttctt gctaccagca acggttggag
    12961 tggttatggt aggagaacct ctttatacgg tcttctatgg taagccagat agtttggctc
    13021 tggtcttatt tgtctttgca gttttgcagt ctattatttt aggcttgtac atggtcttgt
    13081 ctccaatgct tcaggccatg ttccgcaacc gcaaggccgt tctctatttt atctatggtt
    13141 ctattgccaa gctagtcttg caactaccta ccatcgccct cttccacagt tatggtcctt
    13201 tgatttcaac aaccattgct ctcatcattc ctaacgtctt gatgtatcgg gatatttgta
    13261 aagtaactgg tgtcaagcgc aaggtgattt tgaagcgaac cattttaatc agtttgctga
    13321 ccctagtcat gtttctgtta ataggaacca tccagtggct gttaggattt ttcttccaac
    13381 caagtggacg tttgtggagc ttcttttatg tagctcttgt cggtgccatg gggggtggac
    13441 tttatatggt tatgagtctg cgtacctatt tattagataa ggtaatagga aaagcccaag
    13501 cagatcgcct gcgagcaaaa tttaagcttt cgtaaggtag catttataaa taaaaggaat
    13561 aagttgaaca atcttttagg agaacttgaa acttattcct tttttagcgt caaaatagct
    13621 aaaattatct ttcaaaaata gaaaatgagg tttttttgat tttttggaaa aaacaattga
    13681 ctaaacaaac ccagagttgt ataataaaac aaatatttaa agcaggaggt tctggaaatg
    13741 aaaaagtcta agagcaaata tctaaccttg gcaggtcttg tcctgggtac aggagtttta
    13801 ttgagcgcgt gtggaaattc tagcactgca tcaaaaacct ataactatgt ttattcaagt
    13861 gatccatcta gtttgaacta tctagcagaa aaccgcgcag caacatccga tattgttgca
    13921 aatttggtag acgggttatt agaaaatgac caatatggga atattattcc atcattagca
    13981 gaggattgga ctgtttctca ggacggtttg acctatacct acaaacttcg taaggatgcc
    14041 aagtggttta cttctgaggg agaagaatat gcgcctgtaa ctgcccagga ttttgtgaca
    14101 ggtttgcaat atgcagctga taaaaaatca gaagctttgt atctagtgca ggactctgtt
    14161 gctggtttgg atgactatat cactggtaaa acaagcgact tttcaactgt cggtgtcaag
    14221 gcacttgatg accaaacggt tcaatatact ttggttaaac cagaacttta ctggaattca
    14281 aaaacacttg caacgatact ttttcctgtt aatgcagatt tcctgaaatc aaaaggggat
    14341 gattttggga aggcggatcc atctagtatt ttgtacaatg gacctttctt gatgaaagca
    14401 cttgtctcaa aatctgctat tgaatataag aaaaacccta attactggga tgctaagaat
    14461 gtctttgtag acgatgtgaa attgacctac tatgatggta gcgaccaaga atcactggaa
    14521 cgtaatttta cagctggtgc ttatactacg gctcgtcttt ttcctaacag ctccagctat
    14581 gaagggatta aagaaaaata caaaaacaat atcatatata gtatgcaaaa ttcaacttca
    14641 tatttcttta attttaacct agataggaag tcttacaatt atacttctaa aacaagtgac
    14701 attgaaaaga aatcgactca ggaagcagtt ctcaataaaa acttccgtca ggctatcaat
    14761 tttgcttttg acagaacatc ttatggggct cagtctgaag ggaaagaagg tgcaacaaag
    14821 attttgcgta acctagtggt tcctccaaac tttgtcagta tcaagggaaa agactttggt
    14881 gaagttgtag tctctaagat ggtcaactat ggtaaggaat ggcaaggtat caactttgcg
    14941 gatggtcaag acccttacta caatcctgag aaagccaagg ctaagtttgc ggaagctaag
    15001 aaagaactcg aagcaaaggg tgttcaattc ccaatccact tggataagac tgtggaagta
    15061 acagataaag taggcataca aggagttagt tctatcaaac aatcaattga atctgtttta
    15121 ggttctgata atgtagtgat tgacattcag caattaacat cagatgagtt tgacagttca
    15181 ggctactttg ctcaaacagc tgctcagaaa gactatgatt tatatcatgg cggttgggga
    15241 cctgattatc aagacccgtc aacctatctc gatattttta atactaatag tggaggagtt
    15301 ctacaaaatc ttggactaga gcctggagaa gccaatgaca aggctaagga agttggactg
    15361 gatgtctata ctcaaatgtt ggaagaagct aataaagagc aagatccagc caaacgttat
    15421 gagaaatatg ctgatattca agcttggttg attgatagtt ctttagttct tccaagtgtt
    15481 tcgcgtgggg gaacaccatc attgagaaga accgtaccat ttgctgctgc ctatggttta
    15541 accggtacaa aagggattga atcatataaa tacctcaaag tacaagataa gattgtcaca
    15601 acagacgaat atgcaaaagc tagagaaaaa tggttgaaag aaaaagaaga atccaataaa
    15661 aaagcccaag aagaattggc aaaacatgtc aaataaaatc taattgtaga taagtttgtg
    15721 taagaagtct ttgtgcttaa aaacgcataa tatcaggtat ataaaatcct agatgttatg
    15781 cgttttgtta taggaagatt tattagattt tatcctcaaa ttgagttatt cccgacttta
    15841 tccgttgaaa tattataagg agtatttatg aaattaaaat tattaagagt agatactaag
    15901 gtgattatgg ggagtttctt acttgttctg tctagtctac ttgctttgtt gcttcccctt
    15961 atcttaaagg gtttaataga tgggagttct attgaaaata taggttccaa agtatttcaa
    16021 tcgtttttga tttttattgg tcaagccttg ttttcttcta ttggttacta tctgtttagt
    16081 caatcgggtg aaaaaaagat agcaaaaatc aggaaaaaag tgatagaggg gttgatttat
    16141 gcagagaaat ccttctttga taagagccaa agtggggagt tgacttctgc cattgtcaat
    16201 gacacgagtg tcattcgtga gtttttaatt acgactttcc caaatattat tctgagttta
    16261 gttatggtac ttggttccat tgtagtctta tttagtcttg attggaatct ttctctactt
    16321 ttattcatca ctcttccttg tatgatgttt attatcttgc tcctttccaa tatcagtgaa
    16381 aagtatagtc gtcgtttaca ggaggaaatc ggatttttaa cagggtaatt gactgaaaag
    16441 attcaagaac atgaattaat taagactaac caagcagaga aaagtgtaca ggatgttttg
    16501 gataattgta ttgaaagggt acaaaacaat tcactgaaat cagatagggt tacttctttt
    16561 gagaccccgt ttgctctctt atttatcttt gcgactatag ctgtgatgct aacctatggg
    16621 ggttatcggg tcagcgcagg atatatatct gtgggaacct tggtttcgtt tttgatttac
    16681 ctctttcaat tacttaatcc tattagtaat atagctaatt ttgtaactgt ttattctagg
    16741 agcaagggat cttcagttgc actggagaac ttgcttgcag ttcctaaaga aaaatttgag
    16801 tgaggaaaat cggtatcagg acaagggttg aattt
//
LOCUS       DAVBNN010000044        16747 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBNN010000044 DAVBNN010000000
VERSION     DAVBNN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.044"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            74..538
                     /locus_tag="VQ847_001514"
     CDS             74..538
                     /locus_tag="VQ847_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3050832.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            696..1121
                     /gene="lacA"
                     /locus_tag="VQ847_001515"
     CDS             696..1121
                     /gene="lacA"
                     /locus_tag="VQ847_001515"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3050833.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1152..1667
                     /gene="lacB"
                     /locus_tag="VQ847_001516"
     CDS             1152..1667
                     /gene="lacB"
                     /locus_tag="VQ847_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3050834.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1678..2607
                     /locus_tag="VQ847_001517"
     CDS             1678..2607
                     /locus_tag="VQ847_001517"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3050835.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2609..3589
                     /gene="lacD"
                     /locus_tag="VQ847_001518"
     CDS             2609..3589
                     /gene="lacD"
                     /locus_tag="VQ847_001518"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3050836.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3823..4659
                     /locus_tag="VQ847_001519"
     CDS             3823..4659
                     /locus_tag="VQ847_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3050837.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4695..5012
                     /locus_tag="VQ847_001520"
     CDS             4695..5012
                     /locus_tag="VQ847_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3050838.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5012..6703
                     /locus_tag="VQ847_001521"
     CDS             5012..6703
                     /locus_tag="VQ847_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3050839.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6918..8324
                     /gene="lacG"
                     /locus_tag="VQ847_001522"
     CDS             6918..8324
                     /gene="lacG"
                     /locus_tag="VQ847_001522"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3050840.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8414..8626
                     /locus_tag="VQ847_001523"
     CDS             8414..8626
                     /locus_tag="VQ847_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3050841.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(8905..9666)
                     /locus_tag="VQ847_001524"
     CDS             complement(8905..9666)
                     /locus_tag="VQ847_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3050842.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9848..10810)
                     /gene="nrdF"
                     /locus_tag="VQ847_001525"
     CDS             complement(9848..10810)
                     /gene="nrdF"
                     /locus_tag="VQ847_001525"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3050843.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10998..13157)
                     /gene="nrdE"
                     /locus_tag="VQ847_001526"
     CDS             complement(10998..13157)
                     /gene="nrdE"
                     /locus_tag="VQ847_001526"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3050844.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13238..13456)
                     /gene="nrdH"
                     /locus_tag="VQ847_001527"
     CDS             complement(13238..13456)
                     /gene="nrdH"
                     /locus_tag="VQ847_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3050845.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13807..14070
                     /locus_tag="VQ847_001528"
     CDS             13807..14070
                     /locus_tag="VQ847_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3050846.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14076..15809
                     /gene="ptsP"
                     /locus_tag="VQ847_001529"
     CDS             14076..15809
                     /gene="ptsP"
                     /locus_tag="VQ847_001529"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3050847.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16064..>16747
                     /gene="phtA"
                     /locus_tag="VQ847_001530"
     CDS             16064..>16747
                     /gene="phtA"
                     /locus_tag="VQ847_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3050848.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5214 a         3020 c         3475 g         5038 t
ORIGIN      
        1 tatcaatcat gaactaggat tctagttttg caggaagtct aataaagaaa ctagcaaggt
       61 caggccttac tttattggtg gacatccagg atttaattgt cttctacttg atgatgaagt
      121 ctatgaagat tattatctag agtttgagaa agaagagatt tgctctgttc cacgtccttt
      181 cccagaaaca ggtatgttgg atttccaaga tagaagtcca tggctagagg gacaaaaaga
      241 aatagatctt agttatgatc ttttcagcac agatgcagtg actttggatg aattgcaatc
      301 tcgaacaatt gcccttcgtt ctcttaaaca tgataaggga ttgaaagtgc attttgcaga
      361 atttccaaac ctcatcatct ggtcaacttt gaacaaggga cctttcatta cctttgaacc
      421 atggtctggc ttgtcaacat tccttgaaga aggagatcat ttagaagata agaagaatgt
      481 ttgtctctta gaagccaatc aggttgaaga attagggttt gagatagaag ttttataaaa
      541 aaagtaaaaa ataaataaca aaaacaaaca caaactgttg acttcttcaa acaatagtag
      601 tatattatgt ttgtgaggac taattgactg ttttttaaag acagccaata cactgctgga
      661 atccagcata gaaaaaataa aaaggagtat acaatatgtc tattgttatc ggtgcagatg
      721 ctgcaggttt gagattgaaa gaagttgtga aagacttctt agaaaaagaa aacttccacc
      781 ttgtggatgt tacagctgaa ggtcaagact ttgttgatgt gactctcgct gttgctgcag
      841 aagtaaacaa agaagaacaa aaccttggta tcgtgattga tgcttatgga gctggtccat
      901 ttatggttgc aactaagatc aaaggaatgg ttgctgcaga agtatctgac gaacgttcag
      961 cttatatgac tcgtggccac aacaactcac gtatgatcac tatgggggca caacttgttg
     1021 gtgatgaatt ggctaaaaac atcgctaaag gatttgttaa tggtaaatac gacggtggtc
     1081 gtcaccaaat ccgggttgac atgttgaaca aaatgtgcta attagattat agtaagaaag
     1141 gtaagttaaa aatgagaatt gcaattggat gtgaccacat cgtaacagat gaaaaaatgg
     1201 cggtttcaga atttttgaaa tcaaaaggat atgaagtcat tgactttggt acctatgacc
     1261 atacacgtac tcactaccca atctttggta aaaaagtagg ggaagcagta actagtggtc
     1321 aagctgatct cggggtatgt atctgtggta ctggtgttgg tatcaacaac gctgtaaata
     1381 aagttccagg tgttcgttct gccttggttc gtgatatgac aacagccctt tatgctaaag
     1441 aacaattgaa cgccaacgtt atcggttttg gtggtaagat tactggtgaa ttgcttatgt
     1501 gtgatatcat cgaagctttc attcatgctg aatacaaacc atctgaagaa aacaaaaaat
     1561 tgattgcgaa aattgaacac cttgaaagtc acaatgctca acaaacagac gcaaacttct
     1621 tcactgaatt ccttgaaaaa tgggatcgtg gagaatacca cgactaagag gtaacctatg
     1681 attttaacag ttacaatgaa cccatccatt gatatttcct atcccttgga tgagttgaag
     1741 attgatactg tcaatcgtgt ggtggatgta accaaaacgg ctggtggtaa gggactcaat
     1801 gttacccgag tactttcaga atttggcgat tctgttcttg ctactggttt agtgggtggc
     1861 aaacttggtg agtttttggt tgaacatatc gataatcaag taaagaaaga tttcttctca
     1921 attcagggag aaactcgtaa ctgtatcgct attctccacg gagacaacca aacagaagtt
     1981 cttgaaaaag gtcctgaagt attggaacag gaaggtcaag actttttgga acatttcaaa
     2041 aaactcttgg agtcagttga agtagtggcc atctcaggta gtctgccagc tggccttcca
     2101 gttgattact gtgcgagctt ggtagaactt gctaatcaag ctggcaagcc tgtagtcttg
     2161 gactgctcag gtgcagcact tcaggctgtt cttgaatcac cccataaacc aacagtcatc
     2221 aaaccaaata atgaagaatt gtctcagctt cttggaagag aagtttctga ggatttggat
     2281 gaattaaaag aagtacttca agaacctttg tttgcaggga ttgaatggat tatcgtttca
     2341 cttggtgcca acggtacttt taccaaacat ggtgacactt tctacaaggt agatattcct
     2401 agaattcagg cggtaaatcc tgttggatct ggagactcta ctgtggcagg aatttcttca
     2461 ggacttcttc acaaagaatc ggatgcagaa ttactcatca aggcaaatgt ccttggtatg
     2521 ctcaatgctc aagaaaaaat gactggtcat gtcaacatgg ccaactatca agctctatat
     2581 gatcaattaa tagtaaaaga ggtataaaat ggctttaaca gaacaaaaac gtgtacgctt
     2641 agaaaaactt tctgatgaaa atggtatcat ctcagctctt gcatttgacc aacgtggtgc
     2701 tttgaaacgc ctcatggctc aacaccaaac agaagaacca actgtggccc aaatggaaga
     2761 acttaaagtt ttggtagcag atgaattgac taaatacgct tcatctatgc ttcttgaccc
     2821 tgagtatgga cttccagcaa ctaaagctct tgatgaaaaa gctggtcttc tccttgctta
     2881 tgaaaaaaca ggttatgaca caacaagcac aaaacgcttg ccagactgct tggatgtttg
     2941 gtctgcaaaa cgtattaaag aagaaggtgc agatgcagtt aaattcttgc tttactatga
     3001 tgtagatagc tcagacgaac tcaatcaaga aaaacaagcc tacatcgaac gcatcggttc
     3061 tgagtgtgtg gctgaagata tcccattctt ccttgaaatc cttgcttacg atgaaaaaat
     3121 tgcagacgca ggttctgtag aatacgctaa agtaaaacca cacaaagtta tcggtgctat
     3181 gaaagtcttt tcagacccac gctttaacat tgatgtcttg aaagttgaag ttcctgttaa
     3241 cattaaatat gttgaaggct tcgctgaggg tgaagtggtt tacacacgtg aagaagcagc
     3301 agccttcttc aaagcgcaag atgaagcaac gaacttgcca tacatctact tgagtgctgg
     3361 tgtatcagct aaactcttcc aagatactct tgtatttgct catgaatcag gtgcaaactt
     3421 taacggagtt ctttgtggcc gtgctacatg ggcagggtca gttgaagctt acatcaaaga
     3481 tggtgaagca gcagctcgcg aatggcttcg cacaactgga tttgaaaaca ttgatgagct
     3541 caataaagtt cttcaaacaa cagcgacttc atggaaagaa cgtgtgtaag aaagtcctcc
     3601 tagtttagga acatgaatct aaaaaaattt aaaaaaagtt gtatgtaaag gtttacaaaa
     3661 taacttactt gtgctatact taaatcacaa gttaatacaa ggtgagtgtt actaagtaat
     3721 attaggcatg atcacaggtg aattagaaat cagctgattt tctagttcat ttgtggtcat
     3781 tttttgtact catatacctt taaaatataa aaggaggttg acatgtatcg aattctaaat
     3841 ccaatgaatc acaatgtctc gcttgtcaga aatgataagg gagaagaggt gattgtaatt
     3901 ggtaagggga ttgcattcgg aaagaagaag ggggatttga ttgctgaaaa tcaggttgag
     3961 aaaatctttc ggatgaagac cgaagagtcc agagaaaact ttatggctct tctcaaagat
     4021 gttccgcttg attttatcac agtgacctat gaaattattg ataagctatc aaagaaatat
     4081 cattatccga ttcaagagta tctctatgta accttgacag atcatattta ctgttcttat
     4141 caagctctaa ctcaaggaag gtacaaggat agtaatctgc cagatatttc cgctaagtat
     4201 cctgtcgctt ttcaaatcgc aaatgaagct tttgaaattt accgtcagaa gctagcagat
     4261 cattttcctg aggacgaaat tattcggatt gcttatcatt tcattaatgc tgaaggtgaa
     4321 aatgaagtgg aacttgtgga gtcgattgat aagaggaaag aaattctcag gaatgttgaa
     4381 gaagttttaa cggactatgc aattcaacga actaaaaaga ataaccattt ctatgatcgc
     4441 tttatgatcc atttgaatta tttcttggat tatttagaca gatctagaga tgataaccaa
     4501 tcacttctgg atatggaaga tcatattaaa caatcctatc caaaagcctt cgagattggt
     4561 tccaagatct atgatgtgat tacgcaacat acgggtcttg atttgtataa aagtgaacga
     4621 gtttatctag ttctacatat ccaacgttta ttgtcataaa aatttattta aaactatata
     4681 aggagaattc tatcatgaat agagaagaag taacattgtt aggttttgaa atcgtagcct
     4741 atgctggcga tgctcgttca aaactattgg aagccttgaa ggctgctgaa gctggtgatt
     4801 ttgaaaaagc ggacgctctg gtagaggaag ctggtagctg tattgcagag gctcaccacg
     4861 cgcaaacaag tctattgact aaggaagctt ctggtgagga cttagcgtat agtgtgacca
     4921 tgatgcatgg tcaagatcac ttgatgacaa ctatcttgtt aaaagaccta atgcaccatt
     4981 taattgaact ttacaagaga ggagttaaat aatgaataaa ctaattgcat ttatcgagaa
     5041 aggaaagcct ttctttgaaa aactatctcg taatatctat cttcgtgcta ttcgtgatgg
     5101 tttcattgca ggtatgcctg ttattctctt ctcaagtatc tttatcttga ttgcctttgt
     5161 accaaactca tggggcttta aatggtctga tgaagttgta gcctttctga tgaaacctta
     5221 tagctattct atgggtattc tggctctctt ggtagctggt acaacagcta agtcattgac
     5281 tgactcagta aaccggagca tggaaaaaac caatcaaatc aactatatgt caacattgtt
     5341 ggcagcaatt gttggtttgt tgatgttggc agctgatcct atcgaaagtg gtctagctac
     5401 tggattcttg ggaacaaaag gtttgctttc agccttcctt gctgccttcg ttactgtagc
     5461 catctataag gtctgtgtta agaacaacgt cactattcgt atgcctgacg aagttccacc
     5521 aaatatctca caagtcttta aagatgtgat tccattcact ctatcagtgg tttctcttta
     5581 tgctcttgat ttactagctc gtcattttgt tggttctagt gtggcagaat caatcggtaa
     5641 attcttcgca ccactcttct cagcagcaga cggatacctt ggtattacca ttatctttgg
     5701 tgcctttgcc ttcttctggt ttgttgggat tcatggtcca tctatcgttg aacctgctat
     5761 cgcagcgatt acctatgcaa atgctgaagt caacttgaac cttctccaac aagggatgca
     5821 tgcagacaag attcttactt ctggtacaca aatgtttatc gttaccatgg gtggtacagg
     5881 tgcgacattg gtcgttccat ttatgttcat gtggttgaca aaatcgaaac gtaaccgtgc
     5941 aatcggacgt gcttcagtag ttcctacctt cttcggtgta aatgaaccaa tcttgtttgg
     6001 tgcacctctt gttttgaatc caatcttctt cattccattt atctttgctc caattgcaaa
     6061 cgtatggatt ttcaaattct ttattgaaac tcttggaatg aactcattca ctgctaatct
     6121 accatggaca actccagctc cactaggtct agttcttgga actaacttcc aagtgctatc
     6181 attcattctt gctgcccttc taattgtggt tgacgtagtt atttattacc cattccttaa
     6241 agtctatgat gaacaaattc ttgaagaaga acgttcaggt aagtctaatg atgaattgaa
     6301 agaaaaagtt gctgcaaact tcaacactgc aaaagcggat gctattcttg aaaaagcggg
     6361 tgtcgatgca gcacaaaata ccatcactga agaaacaaat gtcctcgttc tctgtgctgg
     6421 tggaggtaca agtggactcc ttgcaaatgc tttgaataag gcagcagcag aatacaatgt
     6481 ccctgtgaaa gcagcagcag gcggctatgg tgctcaccgt gaaatgttgc cagagtttga
     6541 tttggttatc cttgctcctc aagttgcttc aaactttgaa gatatgaagg cagaaacaga
     6601 taagctcggt attaaacttg ctaagacaga aggcgctcaa tacatcaaat taactcgtga
     6661 tggaaaaggt gccctagcat tcgtacaaga gcaattcgat taaggctagg aactgtgaaa
     6721 cagtctccca tcgttacgga aatcgctatg gcgaatttcc taatcgcctt attaattcgt
     6781 cggtaaaaag atatcgtttt tacctcctca tgtcacaatt cagtgacttg gtacaagaag
     6841 tgagatggag aagcatggct cactgactcc tctcctctca cttttacttt atttaaatca
     6901 agaaataggt gaaaaaaatg acaaaaacac ttccaaaaga ctttattttc ggtggcgcaa
     6961 cagctgctta tcaagcagaa ggtgctacac atactgatgg aaaaggacca gttgcttggg
     7021 ataaatatct tgaggataac tactggtaca ctgccgaacc agctagtgat ttttacaatc
     7081 gatatccagt tgacctcaag ctagcagaag agtatggtgt caatggtatt cgaatttcta
     7141 ttgcctggtc acgtattttc ccgactggtt acggccaagt aaatgttaaa ggtgttgagt
     7201 tttatcataa tttatttgca gagtgtcaca aacgtcatgt tgagcccttt gtaactcttc
     7261 atcactttga cacgccagaa gctctccatt caaatggaga cttcttaaac cgtgaaaata
     7321 tcgaacattt tgtagactac gctgccttct gttttgaaga atttccagaa gtaaactatt
     7381 ggacaacctt taatgaaatt ggaccaatcg gtgatggtca atatttggtt gggaaattcc
     7441 ctccaggtat ccagtacgac cttgccaaag tctttcaatc acaccacaat atgatggtgt
     7501 ctcatgcgcg tgcagtcaag ctatataaag ataaaggcta taaaggggaa attggtgttg
     7561 ttcacgctct gccaaccaag tatcctttgg atcctaaaaa tccagcagat gttcgtgcag
     7621 ctgagttgga agatatcatc cacaataaat tcatcttaga cgcaacttat ctaggtcgct
     7681 attcagctga aaccatggaa ggtgtcaacc atatcttatc agtcaatggt ggtagtttgg
     7741 atcttcgtga agaagatttt acaacattag aagctgcaaa agacttgaat gatttcctag
     7801 gaatcaacta ctatatgagt gactggatgg aagcctttga tggagaaact gaaattatcc
     7861 ataatggtaa aggtgaaaaa ggaagctcta agtatcaaat caaaggtgtt ggtcgtcgtg
     7921 tagctcctga ctatgtacca cgcacggatt gggattggat tatctaccct caaggtttgt
     7981 atgaccaaat catacgtgtg aagaaagatt atcctaacta caagaagatt tacatcactg
     8041 aaaatggtct cggctataaa gatgagttcg ttgataacac tgtttacgat gatggtcgta
     8101 ttgattacgt gaaacaacac ttggagatct tgtctgatgc gattgcagat ggagctaatg
     8161 taaaaggtta cttcatttgg tcattaatgg atgtcttctc atggtcaaac ggttatgaaa
     8221 aacgttacgg tctcttctac gtagattttg aaactcaaga acgttatcct aagaaatcag
     8281 ctcactggta taagaaagta gcggaaactc agattataga ctagtagaat tagtcattag
     8341 atatagaatt ttagtgagtc aaaaagatgt tcaaagattt tatccaatct atttatgaaa
     8401 aaaagtttat attataaatt tcgaaaaatg ctctcaaata ccgtgtttga cgagtgaaga
     8461 attgaaaagt cttggaaaat ggtatgtctc gactggtaaa gaatggattt gtcattcaga
     8521 tgatgagctg gaagaattta aaaatctatt tttaaatttt atcaatcctg aagaatggga
     8581 tactatctcc tttgattcag attttatgcc gtttcaacaa tcgtaaccaa tttctcaaaa
     8641 aagttaaatc ttatatttag tactctgtaa aactcttatc taatcacgtt gcttatactc
     8701 aatgaaaatc aaagagcaac tttaaactag gaagcgagtc gcagatttct caatgcatag
     8761 ctttgaggaa ttgggcaaaa agtctttgat atagaaaaac gcatagtatc aggtgtttca
     8821 acacctgata ttatgcgttt tattgtggga agatttactt tttttcttct gaaattgagt
     8881 tgttacccag gctctttcag tttattaagg cttgatgact ttaatgtgtt tagatagctt
     8941 aaaaaggatt gaatcactta gtttagaatc tgaaacaata gtatcaagat ttgatacatt
     9001 ataaaaagta taaaaatcaa acttattgaa cttgctatga tctgcgagta aatatttttt
     9061 attagaatta tttaaagcga tgcgttgagc ctctccctct tcctcgctaa aagtagctag
     9121 agctccgttt tgaataccat tacagctaac gaaagcttta gaaaattgga gattagagag
     9181 attttgtagg gtcaatgtac caacaaaagc acctgtaata tcgcgataat ttccacctat
     9241 taaaatcaaa tctgttaatt ttcgttcgct taaaatcaga aaaacaggta gactgttggt
     9301 tacgacgcgg atattgtcaa taggcaactc acgcgcaaaa aactctaatg ttgttcctgg
     9361 tccaatgaaa atagtttctc tttcttctac tagactgcct gcaaaatggg ctatttcttg
     9421 tttttctgcc gtttggaggg cttgtttttc aatatttgat cgctcattag tcaaaaggga
     9481 gttggttcga agtttttcag ctccaccatg cacacgaatc agcaaatctt tatcagctaa
     9541 ttcctgtaaa tagcgccttg cagtcatatc tgaaacggct atttcgtcca taatctgttt
     9601 aactgttatg gttcctttac tatttactat ctctaaaatt ttggttaatt tttcttgttt
     9661 gagcatatta tcacctcgtt tcctactact atcttaccat aaacaaactc atcattcaaa
     9721 tacaaaaaca acaaaatgaa acaaaaacaa aaatatcgaa gtttgttttc aaaactttcg
     9781 atatttttgt tgggttataa ctttgatgtt tctagtttac tttttgatga ttgagagtga
     9841 tggagaatta gtctaaaccg tagttatagt catcgtcttg catggcttca acttcgccaa
     9901 gaaggtaacc atttccgact tgagagaaga agtcatggtt ggaagttcct gttgaaatac
     9961 cgttcataac gattgggttg acatcttcag ctgaatctgg gaaaagtgga tcttgtccca
    10021 tgttcatgag agctttattg gcattgtagc gaaggaaggt tttaacctct tcagtccaac
    10081 caacaccgtc ataaagactc tctgtgtagc cttcttcatt ttcataaaga gtatagagta
    10141 ggtcgtacat ccattctttg agtttttctt gctcttcttc aggcaattca ttgaaaccaa
    10201 gttggaattt gtaaccaatg taggttccgt gaacagactc gtcacgaata atcaatttaa
    10261 tgatttctgc aacgttggct agtttgttgt taccgagata gtagagggga gtgaagaaac
    10321 cagagtagaa gaggaaggtt tcgaggaaga cgctggcaac tttcttttca agtgggctgc
    10381 cgtttaggta gatttcgttg acaatctcag ccttcttttg taggtaagga ttggtattgg
    10441 tccattcgaa aatttcttca atctcagcct tagtattcaa ggtagaaaag attgatgagt
    10501 aagatttagc gtggacagat tccataaatt ggatgttatt gaaaacagct tcctcatgtg
    10561 gtgtacggat gtctgcgcga agggcttgaa ccccagtttc agattgcata gtgtcaagaa
    10621 gggttaaacc accaaaaact tttccgacca agtctttctc tttgttagat agctttctcc
    10681 agtcatccaa gtcgtttgat aagggaatac gtgtatcgag ccaaaattgc tccgtcagtt
    10741 tttcccaagt tgatttgtcg atgacatctt cgatggcatt ccagttaatg gctttgtagt
    10801 aagtttccat ttaaaatctc tttctgtgtt tagtattgcg aactcacaat tatttctact
    10861 ttaccataat tctataggag tatcgcacaa aaagtcggaa gcccgacttt taaaatgtta
    10921 cataaattat gttatgacat agtagatttg attttatcag tgctgcttag ggaaaaataa
    10981 tgtttctatg ctagaaacta aatcacacag ctttcacatt ggttggcgcc gacttctcca
    11041 ccgtcatctg taaaggtacg gacgtagtag atagacttga ttcccttgtt aaaggcatag
    11101 ttacgaagga tggacaaatc acgtgtcgtt tgtttatttt ccctcttcca ttcgtaaagg
    11161 ccttttggaa tgtcactgcg catgaagagg gtgagtgaaa gtccttgatc cacgtgttca
    11221 gtcgcagcag cgtaaacatc gatgacttta cgcatatcca tatcgtaggc agaagtgtag
    11281 taaggaatgg tttctgtaga caagccagca gcagggtagt agattttacc aattttcttc
    11341 tcttggcgtt cttcgatacg ttgcgtaatc gggtggatag aagcagaaac gtcgttgata
    11401 tagctgatag aaccatttgg cgctacagca aggcgatttt ggtggtaaag accatcttct
    11461 tgaaccttgt cgcgaagttc agcccaatca gcaacaccag ggataaaaac atttttgaag
    11521 agttctttaa cacggtctga tgttggaaca aattcaccag ttacatactt gtcaaagtaa
    11581 cttccgttag catagtctga tttttcaaag ttgtggaagg taataccacg ttcacgcgca
    11641 atattgtttg actctaccaa ggtccagtag ttcataagca taaagtagat gcttgtaaat
    11701 tcaacagact caggtgaacc atattcaatg agttgttggg caaggtagct gtgcagtccc
    11761 atggcaccga gaccaaaggt gtgggcttgg ctatttccat ggtcaatcgt tggtacagct
    11821 acgatatgtg aactatctgt aacgaaagta agggcacgaa ccatagcacg gatagaacga
    11881 ccaaaatcag gtgaagtcat catgttaacc acgttggttg aacccagatt acatgaaaca
    11941 tctgttccca tttgaaggaa ttcttgagca tcgttgatca agcttggttc ttgaacttga
    12001 agaatctcag aacacaagtt actcatgata atctttccat caacaggatt tgcacggtta
    12061 gccgtatcga tgttgactac ataaggatag ccagactctt gttgcaattt agagatttca
    12121 gtttccaaat cccgcgcctt gatttttgtc ttgcgaatat ttggatttgc gaccaattca
    12181 tcgtattttt cagtaatgtc gatgtaattg aatggcacac cgtattcttt ttctacagag
    12241 taagggctga agaggtacat ttcttcattt ttacgagcca attcgtagaa tttatcaggt
    12301 actacaacac caagtgatag agtcttgaca cgtacttttt catcagcgtt ttctttctta
    12361 gttgaaagga aagcgatgat atctgggtga aagacgttga ggtagacaac accagcacct
    12421 tgacgttgcc ccaattggtt ggagtaagag aagctgtctt caaaaagctt cataacagga
    12481 acgacacctg aagcagctcc ttcatagcct ttgataggtg caccagcttc acgaaggttg
    12541 ctgagggtaa ttcccacacc accaccaata cgtgaaagtt gaagagctga gttgatagaa
    12601 cgtccgatag agttcatatc atccgtcact tggattagga aacaagatac caactcccca
    12661 cgacgagcac gtccagcatt caagaaggaa ggagtagcag gttggtagcg ttggtggatg
    12721 atttcattgg caatatcgat tgcaacagct tcattcccat cagcgaaata aagggcgttg
    12781 aagaagacac ggtcttccat attttcaaga tagtattcac cgtcattagt ctttaaggca
    12841 tattgattgt aaaatttata agctgccatg aatgacttga attggaagtt ttggtctttg
    12901 ataaattgag ccaattcttc caagaactct ggacggtatt tcttgataaa ggctgtttcg
    12961 atgtagttgt gttcaatgag gtaattgatt ttgtctttga ttgaatcaaa aaccatagtg
    13021 tttggaacta cattttcttt aaagaaagca tccaaggctt ccttatcttt atgaagcatg
    13081 atttgtccat taacaggacg gttaatttcg ttattaagac ggaagtaagt cacgtcttca
    13141 agatgtttta atcccataaa atttccctta tctaattaca aaagaaaggc ttctaagtta
    13201 gccctaaaag cagtttcttc tggatgatgt actaagatta tgctaattgt ttcagttttc
    13261 ctggttggaa acctgaaaag acttcagttg gtgtttggat aacaggagct gcgctaaaac
    13321 cgagctcttt aacttgatcg acgtactcag gttgctcatc aagattgatt tcacgataag
    13381 agacattatt actgtccaag aaacgcttgg tcattttaca ttggacacaa ttgtttttag
    13441 aataaacggt taccattgtg taactcctct tcaaaattta atactatctt agtatatcag
    13501 aaaataaaat tttgtcaatg atttgaacta aatatagtgg tgttcttttg ttgtttttat
    13561 atataaacac aatatatagt gtttgtattg tgaaatagca atgattatcc tataaattgt
    13621 ttttaaagaa actatatcct gtgttttgtt atctaggata gaagattttc agcaagttat
    13681 ctgaaaggaa attgaaggaa aatccagaaa atgcttgaaa aaaatcctag aagatggtat
    13741 aatactaaat tgtaagggtt atcacatata actcaaaaaa agaaagaaca aaaggagagt
    13801 caaactatgg cttctaaaga tttccacgta gtggcagaaa caggtattca cgcacgtcca
    13861 gcaacattgt tggtacaaac tgctagcaaa tttgcttcag atatcactct tgagtacaaa
    13921 ggtaaatcag ttaaccttaa atcaattatg ggtgttatga gtcttggtgt tggtcaaggt
    13981 gctgacgtaa ctatctcagc tgaaggtgca gatgcagatg acgctatcgc tgcaatctca
    14041 gaaacaatgg aaaaagaagg attggcataa gggaaatgac agaaatgctt aaaggaatcg
    14101 cagcatctga cggtgttgca gttgcaaaag catatctact cgttcagccg gatttgtcat
    14161 ttgagactat tacagtcgaa gatacaaacg cagaagaagc tcgccttgat gccgctctac
    14221 aggcatcaca agacgagctt tctgttattc gcgagaaagc agtaggtacg ctcggtgaag
    14281 aagcagctca agtttttgat gctcacttaa tggttcttgc tgacccagaa atgatcagcc
    14341 aaatcaagga aactatccgt gcgaagaaag tgaatgcaga agcaggtctg aaagaagtta
    14401 cagatatgtt tatcactatc tttgaaggca tggaagacaa cccatacatg caagaacgcg
    14461 cagcggatat ccgcgacgtg acaaaacgtg tattggcaaa ccttcttggt aaaaaattgc
    14521 caaacccagc ttctatcaat gaagaagtga ttgtgattgc gcatgacttg actccttcag
    14581 atacagctca attggacaaa aactttgtaa aagcttttgt aaccaacatt ggtggacgta
    14641 caagccactc agctatcatg gcacgtacac ttgaaattgc tgctgtatta ggtacaaaca
    14701 acatcactga aatcgttaaa gacggtgaca tccttgctgt taacgggatc actggagaag
    14761 tgattatcaa cccaacagat gaacaagcgg cagaatttaa agcagctggt gaagcctatg
    14821 cgaaacaaaa agctgaatgg gcacttttga aagatgctca aacagtgact gctgacggta
    14881 aacacttcga gttggctgcc aatattggta ctccaaaaga cgttgaaggt gttaacaaca
    14941 acggtgcaga agctgttgga ctttaccgta cagagttctt gtacatggat tctcaagact
    15001 tcccaactga agatgagcag tatgaagcat acaaggctgt tcttgaagga atgaacggta
    15061 aacctgttgt cgttcgtaca atggatatcg gtggagataa ggaacttcct tacttcgata
    15121 tgcctcacga aatgaaccca ttccttggat tccgtgctct tcgtatctct atctctgaga
    15181 ctggagatgc tatgttccgc acacaaatcc gtgctcttct tcgtgcgtct gttcacggtc
    15241 aattgcgtat catgttccca atggttgcgc tcttgaaaga attccgtgca gcgaaagcag
    15301 tctttgatga agaaaaagca aaccttcttg ctgaaggtgt tgcagttgcg gataacattc
    15361 aagttggtat catgatcgag attcctgcag cggctatgct tgcagaccaa tttgctaaag
    15421 aagttgactt cttctcaatt ggtacaaatg acttgatcca atatacaatg gcagcagacc
    15481 gtatgaacga acaagtttca tacctttacc aaccatacaa cccatcaatc ctacgcttga
    15541 ttaacaatgt gatcaaagca gctcacgctg aaggtaaatg ggctggtatg tgtggtgaga
    15601 tggctggtga ccaacaagct gttccacttc ttgtcggaat gggcttggat gagttctcta
    15661 tgtcagcaac atctgtactt cgtacacgca gcttgatgaa gaaactcgac acagctaaga
    15721 tggaagagta cgcaaaccgt gcccttacag aatgctcaac aatggaagaa gttcttgaac
    15781 ttcaaaaaga atacgttaat tttgattaat cgaaaagtcc ctgcaactca gttacaggga
    15841 ctttttttga tattttaaaa agaattttca agaaaatctt tcttataaaa agtccaacct
    15901 tgaaaaagta gtggtcagaa caaaaaatac ttaaatggtt cataaaattc ttgacaagtt
    15961 ggagatttag gagtaaacta ttaaccagtt aagtaataga gaggagtttc tgcaatttag
    16021 aaatgaattg caactagaaa tatcaaatag aaagagagtt tcgatgaaaa ttaataagaa
    16081 ataccttgtt ggttctgcgg cagctttgat tttaagtgtt tgttcttacg agttgggact
    16141 gtatcaagct agaacggtta aggaaaataa tcgtgtttcc tatatagatg gaaaacaagc
    16201 gacgcaaaaa acggagaatt tgactcctga tgaggttagc aagcgtgaag gaatcaatgc
    16261 tgagcaaatc gtcatcaaga taacagacca aggctatgtc acttcacatg gcgaccacta
    16321 tcattattac aatggtaagg ttccttatga tgcgattttc agtgaagaat tactcatgaa
    16381 agatccaaac tataagctaa aagatgagga tattgttaat gaggtcaagg gtggatatgt
    16441 tatcaaggta gatggaaaat actatgttta ccttaaggat gctgcccacg cggataacgt
    16501 ccgtacaaaa gaggaaatca atcgacaaaa acaagaacat agtcaacatc gtgaaggtgg
    16561 gactccaaga aacgatggtg ctgttgcctt ggcacgttcg caaggacgct atactacaga
    16621 tgatggttat atctttaatg cttctgatat catagaggat actggtgatg cttatatcgt
    16681 tcctcatgga gatcattacc attacattcc taagaatgag ttatcagcta gcgagttggc
    16741 tgctgca
//
LOCUS       DAVBNN010000045        16457 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBNN010000045 DAVBNN010000000
VERSION     DAVBNN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.045"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ847_001531"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ847_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3050849.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ847_001532"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ847_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3050850.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ847_001533"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ847_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3050851.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ847_001534"
     CDS             3205..3600
                     /locus_tag="VQ847_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3050852.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ847_001535"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ847_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3050853.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ847_001536"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ847_001536"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3050854.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ847_001537"
     CDS             5389..5994
                     /locus_tag="VQ847_001537"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3050855.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ847_001538"
     CDS             5981..7180
                     /locus_tag="VQ847_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3050856.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ847_001539"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ847_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3050857.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ847_001540"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ847_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3050858.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ847_001541"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ847_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3050859.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ847_001542"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ847_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3050860.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ847_001543"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ847_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3050861.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ847_001544"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ847_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3050862.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ847_001545"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ847_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3050863.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ847_001546"
     CDS             14213..14926
                     /locus_tag="VQ847_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3050864.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ847_001547"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ847_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3050865.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ847_001548"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ847_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4952 a         3074 c         3688 g         4743 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatcta ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taagattaga attgtttatc
    16441 ccaaatttat ttgaaag
//
LOCUS       DAVBNN010000046        15765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBNN010000046 DAVBNN010000000
VERSION     DAVBNN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.046"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(1..261)
                     /locus_tag="VQ847_001549"
                     /pseudo
     CDS             complement(1..261)
                     /locus_tag="VQ847_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            386..844
                     /locus_tag="VQ847_001550"
     CDS             386..844
                     /locus_tag="VQ847_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3050866.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            857..1465
                     /locus_tag="VQ847_001551"
     CDS             857..1465
                     /locus_tag="VQ847_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050867.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1536..1868
                     /locus_tag="VQ847_001552"
     CDS             1536..1868
                     /locus_tag="VQ847_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050868.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1879..3294
                     /gene="ply"
                     /locus_tag="VQ847_001553"
     CDS             1879..3294
                     /gene="ply"
                     /locus_tag="VQ847_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3050869.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4175..4891
                     /locus_tag="VQ847_001554"
     CDS             4175..4891
                     /locus_tag="VQ847_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3050870.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            5015..5484
                     /locus_tag="VQ847_001555"
                     /pseudo
     CDS             5015..5484
                     /locus_tag="VQ847_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5501..6322
                     /locus_tag="VQ847_001556"
                     /pseudo
     CDS             5501..6322
                     /locus_tag="VQ847_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            6329..7300
                     /locus_tag="VQ847_001557"
     CDS             6329..7300
                     /locus_tag="VQ847_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3050871.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMV"
     gene            7426..7788
                     /locus_tag="VQ847_001558"
     CDS             7426..7788
                     /locus_tag="VQ847_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3050872.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7785..8288
                     /locus_tag="VQ847_001559"
     CDS             7785..8288
                     /locus_tag="VQ847_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3050873.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8402..8848
                     /locus_tag="VQ847_001560"
     CDS             8402..8848
                     /locus_tag="VQ847_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3050874.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8853..9527
                     /locus_tag="VQ847_001561"
     CDS             8853..9527
                     /locus_tag="VQ847_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050875.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            9688..9879
                     /locus_tag="VQ847_001562"
     CDS             9688..9879
                     /locus_tag="VQ847_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3050876.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            10164..10463
                     /locus_tag="VQ847_001563"
     CDS             10164..10463
                     /locus_tag="VQ847_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3050877.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10460..10777
                     /locus_tag="VQ847_001564"
     CDS             10460..10777
                     /locus_tag="VQ847_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3050878.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            10793..11419
                     /locus_tag="VQ847_001565"
     CDS             10793..11419
                     /locus_tag="VQ847_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3050879.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11452..12213
                     /locus_tag="VQ847_001566"
     CDS             11452..12213
                     /locus_tag="VQ847_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3050880.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            12291..12686
                     /locus_tag="VQ847_001567"
     CDS             12291..12686
                     /locus_tag="VQ847_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3050881.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            12956..13240
                     /gene="groES"
                     /locus_tag="VQ847_001568"
     CDS             12956..13240
                     /gene="groES"
                     /locus_tag="VQ847_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3050882.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            13256..14878
                     /gene="groL"
                     /locus_tag="VQ847_001569"
     CDS             13256..14878
                     /gene="groL"
                     /locus_tag="VQ847_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3050883.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            15016..15765
                     /locus_tag="VQ847_001570"
                     /pseudo
     CDS             15016..15765
                     /locus_tag="VQ847_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567576.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
BASE COUNT         4697 a         2874 c         3624 g         4570 t
ORIGIN      
        1 tccttagata gcgcatggtt atagacttta tcttcaactg ttagtggctt gagtttgctg
       61 gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata attactgtca
      121 gccaagattt taccagcttg tccgactttt ttgataagct gtttttaata cagctaacat
      181 ctctttaaaa gtggtacgct gaacactaac aagacgctta aatcgtgcat cagttagttg
      241 tttacttgct tcataattca tagaactact ataccatatt ttgtttcgca ggaagtctaa
      301 taagttatag tccagttttt actatacttt gatattcaaa tatgttatac tatggttatc
      361 aaagtaaatg aaaggagtta cgaatatgac gccagaagaa atgtacctga cagagcgatt
      421 agacgtacag atagctcatt ttttaaagaa aagcgttcaa catcgtaggc gctataaggt
      481 attaaaaata acagaaatcg tggcaggttt cctcatagct gtcttttgtg ctattcctat
      541 gccaggtgat cgctaccgtt tgatttcggt tgccttatcc agtctcggct tgctgtgtga
      601 ggggattatc aatttgtata atgcaaagga aaattggatt tcttaccaaa aaactgcgca
      661 actcctggag aaagaaaaat tcctctatca atgccaaacg gagaaatatg caggaaagac
      721 caaggctttt gccctatttg tcaagacatg cgaaggtctt atctcagagg agattaacca
      781 gtgggaaagt atccagtcaa aagaagtggc agctagtgca gatgctccag ttaaaaaaga
      841 gtaggaggta gaggaaatgt ctcaatccag ttacctgtcg cccttgctct ggttaaaaaa
      901 agaagccgat aaggaaaaga tgagcgcgac ccagtgccag atatttttct tttactatca
      961 aatgtttgag ctcttatttg ctagagaaag cgacatgaaa gacttatgtc tgggaacgaa
     1021 aggtttttat ttctcgcagt tagagaaaaa tttgctttct ggagtttccc gatttctaaa
     1081 aaacttggag gggaaagtaa ctctcaaggc taaccaagaa gtatcagctc gcaaagccct
     1141 ttttctagcc ttgacaacta gccaatcaga ttggcaggag ttagctcctg tttttgattt
     1201 ttatcagact atcgggaggc ttgaaaatcc ttctctcttg agttctcagg acagacaaca
     1261 tctgatgtgg atttaccagt cagctttgga gaaggattat attgtcaagg ttattggcga
     1321 caagcatttt gtattgaaga gacaagatgc tactaaattg acagcgcgcc aaactcaaac
     1381 tttggaaatt ctgagtcaat cagaagactt ggtcaatcct gtctatgtta cattaggaga
     1441 aaagggggtg ctcttgcttg attaagagag gagatgttgt agctctttat ttgccttttc
     1501 cgactattag tagcgatttg gctgtgaaga atcatatgta tatctgtatt gacaacagca
     1561 tgactaaaaa caaagagttg gttaaaaatc agaccttcaa accagctctc ttgaccagac
     1621 gtttggtcaa gaactttatg atagaagagc cggatctagc tcgtaatcct tttacaagac
     1681 caaccttgat tgacttagat aaggtattta tgttggataa tacggttatt ccgacttctt
     1741 atctagccag acggcgacgc aatgtctcag aagaattgta cgaggaaatt ttggatcact
     1801 tagtccaacc acggctgatt tcgctgaaca agtctgagtt tatgcaactc aatccaggaa
     1861 cttattagga ggtagaagat ggcaaataaa gcagtaaatg actttatact agctatgaat
     1921 tacgataaaa agaaactctt gacccatcag ggagaaagta ttgaaaatcg tttcatcaaa
     1981 gagggtaatc agctacccga tgagtttgtt gttatcgaaa gaaagaagcg gagcttgtcg
     2041 acaaatacaa gtgatatttc tgtaacagct accaacgaca gtcgcctcta tcctggagca
     2101 cttctcgtag tggatgagac cttgttagag aataatccca ctcttcttgc ggtcgatcgt
     2161 gctccgatga cttatagtat tgatttgcct ggtttggcaa gtagcgatag ctttctccaa
     2221 gtggaagacc ccagcaattc aagtgttcgc ggagcggtaa acgatttgtt ggctaagtgg
     2281 catcaagatt atggtcaggt caataatgtc ccagctagaa tgcagtatga aaaaatcacg
     2341 gctcacagca tggaacaact caaggtcaag tttggttctg actttgaaaa gacagggaat
     2401 tctcttgata ttgattttaa ctctgtccat tcaggcgaaa agcagattca gattgttaat
     2461 tttaagcaga tttattatac agtcagcgta gatgctgtta aaaatccagg agatgtgttt
     2521 caagatactg taacggtaga ggatttaaaa cagagaggaa tttctgcaga gcgtcctttg
     2581 gtctatattt cgagtgttgc ttatgggcgc caagtctatc tcaagttgga aaccacgagt
     2641 aagagtgatg aagtagaggc tgcttttgaa gctttgataa aaggagtcaa ggtagctcct
     2701 cagacagagt ggaagcagat tttggacaat acagaagtga aggcggttat tttagggggc
     2761 gacccaagtt cgggtgcccg agttgtaaca ggcaaggtgg atatggtaga ggacttgatt
     2821 caagaaggca gtcgctttac agcagatcat ccaggcttgc cgatttccta tacaacttct
     2881 tttttacgtg acaatgtagt tgcgaccttt caaaatagta cagactatgt tgagactaag
     2941 gttacagctt acagaaacgg agatttactg ctggatcata gtggtgccta tgttgcccaa
     3001 tattatatta cttgggatga attatcctat gatcatcaag gtaaggaagt cttgactcct
     3061 aaggcttggg acagaaatgg gcaggatttg acggctcact ttaccactag tattccttta
     3121 aaagggaatg ttcgtaatct ctctgtcaaa attagagagt gtaccgggct tgcctgggaa
     3181 tggtggcgta cggtttatga aaaaaccgat ttgccactag tgcgtaagcg gacgatttct
     3241 atttggggaa caactctcta tcctcaggta gaagataagg tagaaaatga ctagtagagg
     3301 agaatgcttg cgacaaaaag aggcgatgat ctctctgcgg atatctgaaa gtttatctct
     3361 tgcctagcga tttccattgg agtatgctcg tgatgttaaa atgaatctat caaacagaat
     3421 gtgtaaaaaa gtaaaaaggg tagccaattc cttgatatac aggggattga ttatccttta
     3481 cttgttttag atgattggaa attcaagaat gacacgtatc ggaaatattt tgctgtttat
     3541 atctaatacc catttatgga aaaaatgaaa ttaaatatga acaaatcaat tgctagcaat
     3601 ggtttagaag tgccagtgta ctagtctaat ttctccatct tgggaacacg taaattatac
     3661 tcttcgaaaa tctcttcaaa ccaggtcagc cctatccgca acctcaaaac agtgttttga
     3721 gcaacctgcg gctagctttc tagtttgctt tttgattttt attgagtatt agaggtttgc
     3781 ttagaaactc ttctattgat ttcttagaat acaatagcgc ctataagaac tgttggattt
     3841 caaagtattt acttgaacta tgatatgtct ggagtagact gtcaacaaaa ggtgcagtat
     3901 gattgttttt gtcgcttata tctacaaact tcaaacagta atttgagctg actttgtcaa
     3961 acttggctga aactttctat ttgcagataa tggtctagtt tgttttttga atgtggatga
     4021 gtgtctgttg ataaagatag aaaggtaaga ccatcttagc aggtaaagtg ctatcctagc
     4081 ttgatttgct aataaaatcc atttcctcta gtgaaaatca aaaaaacttg tgttataata
     4141 agaaagatta aaatgtgaaa aaaggagatt cctaatggga cgtaaatggg ccaatatcgt
     4201 agccaagaaa acggctaaag atggagctaa ctctaaagta tatgcaaaat ttggtgtaga
     4261 aatctatgta gcagctaaaa aaggtgatcc agatccagaa tcaaactcag ctttgaaatt
     4321 cgttatcgac cgtgctaaac aagcccaagt gccaaaacac attatcgata aagcgattga
     4381 taaagccaaa ggaaacacag acgaaacctt tacagaagga cgttacgaag gttttgggcc
     4441 aaatggctct atgctaattg tggatacttt gacttctaac gttaaccgta cagcagccaa
     4501 tgtccgtgca gcctttggta aaaacggcgg aaacatgggc gcttcaggtt ctgtttctta
     4561 cctttttgac aacaaaggtg ttattgtatt tggaggtgaa gatgcggacg cagtctttga
     4621 gcaattgctc gaagcggatg tggatgtgga tgacgtagaa gcacaagaag gtacaatcac
     4681 agtttacaca gcgccaactg accttcacaa ggctatcgtt gctctccgtg agtctggtat
     4741 tgaagaattc caagtgactg aattggaaat gattcctcag tcagaagtgg aattgtcagg
     4801 cgaagacctt gaaacctttg aaaaacttta cagcgttctt gaagacgacg aagacgtcca
     4861 aaagatttat acgaacgtag atgggtttta atttaaccta tagaacatga tcctaagtga
     4921 gaaaatcact tgggattttt ttaatcaaga aaatagttct catagaaatt taattattct
     4981 ccagagaact atttttattt agaaggggga gattatggat aaaccgatgt tagtctttaa
     5041 gcgttttggt catcaaattt acctgatggt gcaaaaggaa gccaaacgtt gcggcattga
     5101 atttatgggt gggccgcaag gtcaggttgt gcgttttttg gataatcgcg agaaaaacca
     5161 agacttggtc ttgattaaag atatcgagca ggaactcaat attaccaagt ctgttgctag
     5221 taatctggtt aagcgtatag tgcaaaatgg tttggtggaa ttggaggcga gtcctgttga
     5281 taagcgggct aagtttgttc gtctgacgga caaagcacgt tctcagatgc aacaggttaa
     5341 ggcttttttg aacgcataga caagcagttg atggaagaca ttgatgaaga tgaattactg
     5401 atttttgaga aagttctcgg tcaactacag gcaaatatca agggaatagg aggagagaat
     5461 aaagaaatta gccaaaagaa ttagtagaaa agaatggggg atgattttac tagccattct
     5521 ctttacttgc ttttcggtct atctagagtt ggaagtgccg acctatatct cgaaaattac
     5581 ggatttgcta ggtagtcaag gaactaattt agatgagttg tggcagccgg caagcatgat
     5641 gatgggaatg ccctttcttg ccttcttgtc cgtagttgca gttggatttt ttgcatcccg
     5701 agtggcggct tcttatacta gtaggctgag aagtgatatt tttaaccgag ttttggatta
     5761 ctcgcagaca gagattaaga aattttcaat tcctagcctc ttgatgcgta ctaccaatga
     5821 cattactcaa gttcaaatgt tgattactat ggacttgcaa gtggtaacgt gtggtccaat
     5881 tatggctatc tgggctattg ggaagatttt aggtcattca gaatactggc tctgggccgt
     5941 acttgtggca gtgattgtca acgtcctgat gacgaccgtt ttgatgacgc tagcctttcc
     6001 aaaacagtcc ttgattcagg ggctgacaga taaactgaac agtatcactc gtgagagttt
     6061 aacaggtatt cgtgtcgttc gtgcctacaa tgcagaggat tatcaaaatg aaaaatttgc
     6121 agcagtaaat gatgaattga cccgttaaaa tttgtttgtc aaccgtctta tggctatttt
     6181 gaatcctatc atgatgggga tttcaagtgg tttgagtgtg gcgatttact ggattggggc
     6241 ctatgtgatt aacgacgctg ctccgatagc gcgtctgcct ttctttagtg acatgattgt
     6301 tttcatgtct tatgccatgt aggttgtcat ggacttcctt ctcatgggag cactcttcat
     6361 cgttcttccc cgaactatgg tctctgctaa gcggattaat caagttttag atttgcattc
     6421 ttctatccaa aaccctgctc aagtgcagct gactgatgaa aacttcaaag gtcaggtcga
     6481 gtttaaggat gtgaccttcc gctatgcggc aaattcggag gcagttattg aacatgttag
     6541 ctttaaagca gaaactggtc aaacagtggc ctttattggg tcaataggtt ctggtaaatc
     6601 aactctggtc aatctgattc cacgtttcta cgacgtgtca gcaggagaaa ttctggtgga
     6661 cggtgtcaat gttcaagact atgacttctc tgcgacagct catgctggtc aaagggttgc
     6721 cattgttggg ccgactgggg ctggtaagac aaccattgtc aatcttttga tgaaattcta
     6781 tgagattgat aagggaagta ttcgcattga tggtgtggat accaaggcta tgacgcgttc
     6841 agaagtgcat gatgcctttt caatggtctt gcaggatacc tggctctttg aaggaactat
     6901 tcgagacaat ctcatctata atcaaatagg gattagtgat gaacgaatga tggaagctag
     6961 taaggctgtg ggaattcacc actttattat gaccttgcca gatggctatg ataccatctt
     7021 ggatgacacc gtgaccttgt ctgtaggaca aaaacaacta ttgactattg ctcgtgccct
     7081 tcttaaggat gcaccgcttt tgattttgga tgaggcgact tcttctgttg acacacggac
     7141 agaggaattg atccaaaaag ccatggaccg tttgatggaa ggacgcacat cctttgtcat
     7201 tgcccaccgc ttgtcaacca tccgaaatgc agacttgatc ttggtcatga aagatggaaa
     7261 tatcatcgag caaggcaact atgaggaact gatggtgtaa ggtggcttct acgctgactt
     7321 gtacaatagt caatttacag aagatgaagc agaagaataa atcaaaagaa ggcttgacgg
     7381 ccttcttttt cttatttata ctagtacaca tagaaagaga gaagtatgag tcagaaatta
     7441 tacaatatga aatttgctgc tgtctactta gccttgattg caaaagttga gcgaaagggt
     7501 ggaaaggcag agtcagttca ccaagtgacc agttggttga cagggtatga agtgagtgac
     7561 gttcttactt gtctggatag ggatgttact tacggagatt tttttcgaca agcaccatat
     7621 tatgtccctg aacgaattgc aattacaggg aagatttgcg gtgtccgtat tgaggaaatt
     7681 gatgatcctc tgatgcagga aatacgtcgc ttggacaagc tagtggattg gcttgccaag
     7741 gggaaaacat ctcaacaagt tctagaaaag tatgagaagc ataaatgaaa aattatcaag
     7801 aatggtatcg aaatatcaga tccagactaa ctagtcgtcc aattctttta ttcctattac
     7861 gcagtttcaa tcgtttgatg acagtcgcca tgcccctggt ctatctgatc ttgctagtca
     7921 ccacttacct gcaactagga cttggtcagc aagttggagt ttatgtgctt attcctgcat
     7981 caggttttgt ggccttgtcc ctgtttcgta aaaaaatcaa tcacccgaga ccttatgaaa
     8041 cttgggatat ctgtcccctt cttgataagg atagttcggg acggtcgatg cccagtcgcc
     8101 atgtcttttc tgcaactatc atctccatgg cctgtctgca tgctagtcta cctattggct
     8161 tagtatgctt gatcttttca gctttgctgg ggttggtgag ggttttaggg ggtgttcatt
     8221 atcccaagga tgtcttggtt ggctatgctt gtggtctggt gtggggattc cttttcttct
     8281 tattctgaca tgtaagttaa gctagtccta caaccactta ctgcttcaaa ttgaccactt
     8341 gcttttttgc ccttgtattc ctaacttagc tttgatatag tagagtcaga aaggagatgt
     8401 gatgaagtta cgaattgaga ttgacggcaa tttagaggag actgaaattg tcatcaagac
     8461 ccccactttg acagatgaaa ttgcagactt gcaacggctc ttgcaagaat ccaagtctcc
     8521 taggttgatt ttttacaagg ggacgggtga atattatctg gacttgtcgg aaattctctt
     8581 ctttgagaca gaaggtagca agatttatgc ccatacccag aaaaatgcct acgaagttcg
     8641 gctcaaactc tatgagttag aggctatcct tcctcgctat tttagtcgag tatccaagtc
     8701 aacgatcgtt aatattcggc aaatctattc ggtggacaag tccttttcag gaacgggcac
     8761 catttccttt tatcaaaccc acaaggaggt tcatgtgtca cggcattacc aatccctcct
     8821 aaaagaaaat ctaagaaata tgaggtaaga acatgaaaaa gaaagcattt ggtattgtgt
     8881 tgcttgtact agcagcttta atattagtac aaggaaattt tggaatccct tctctaggag
     8941 ggcacatttg gcccttgatt ggtattgctt tttttgccta ccaatcagtt ggagctttgt
     9001 tgcgtcgcca cttaacttca gcctctttta cagctctagt agccttaatg attgctaacc
     9061 acttttatgg cattttaccg attccaaacc agacactaat ctgggcagga gttctaatcg
     9121 ttctcggagt aaatatgttg actcattcta acagaacttg gaatgggaaa aaatggtggt
     9181 atgatggtga aaaaaacatt cttatagata aggaagttgc ttttgggaca gggactttct
     9241 acaagcaaga ccaagaattg gtagaagacc aagtagaagt tggttttggc aatgcaaaaa
     9301 tctactatga caatgcagag atgttaggtg attttgcaac tttaaatatt gaagtagctt
     9361 ttggtaatgc aactgtctat gttccgcaac actggcgtgt cgatttgaaa gtagaaacat
     9421 cctttggtgc agccaaggcg gacgctcctg tagccccaac cagcaaaacc ttgattatcc
     9481 gtggagatgt ggcttttggg aagttggaaa ttgtctacgc taaataaaaa aatcttcact
     9541 tcaaccatca aaataggcgt actaagagta ggaaattgat gccttgctct gatttcagtt
     9601 ctatggttgt tagactttaa aaaatgaaat gctgccttta aaagttgtat atttttcgat
     9661 attttggctt ttacgtttga tgtatctatg tactacagcg tagatgatgt agtgtcgaat
     9721 gcttttaaaa aacgaatgat attggacagt ttttttgcct ttaattgctc aggaaccatg
     9781 aaagtcagta cttgggttta tgacaaggga gaatggtatt atgtaagttc ttctggttcc
     9841 atgattgcga atgattgggt caaagacaat ggcaagtagt attatctggc ttcatcaggt
     9901 aagatgcttc gcaataccta cacacctgat ggttactacg ttggcaactt aggtgcctgg
     9961 caataagaat aatactcttt gaaaatctct tcaaaccacg tcaacgtcgc cttatctaca
    10021 acctcaaaac cgtgttttga gcagcctgcg gctagctttc tagtttgctc ttagtataag
    10081 aagtcctttt ccttaaagga agaggctttt tacttgcttt tctgctgctt cctcatttgt
    10141 cctgaagcct tttttgtgtt aaaatgaatg gtatgaaagc taaaaaaatg tggatggcag
    10201 gcttggctct gctaggtatc ggaagccttg ctcttgctac gaaaaaagtt gcagatgacc
    10261 gtaagctcat gaagactcag gaagagttga cagagattgt gcgagaccat ttttccgaca
    10321 tgggggaaat tgcgaccctt tatgttcaag tttacgaaag cagtctggag agcttggttg
    10381 gtggcgtcat ttttgaggat ggccgtcatt atacctttgt ctatgaaaat gaagacctag
    10441 tctatgagga ggaagtctta tgatacagcc agcaagttta gaagaattag catctttagt
    10501 ggaaaaagcg ggcaagaagg tcttcctttt tgtggcagac tggtgtggcg attgtcgtta
    10561 tatttatcct gccttaccag agattgaaga gaccaatcca gagttcacct ttattcgaat
    10621 ggaccgagat cagtatatgg atttggccaa actctgggat gtttacggaa ttcctagcct
    10681 tgttgttcta gaaaaggaca aggaaatcgg tcgttttgtc aatcgcgacc gtaaaagtaa
    10741 ggagcaaatt aacgattttt tagcaggatt gaaataggag aaaaaggaaa caatgatttt
    10801 tacgtataac aaagaacatg tcagtgatgt ccttatggtc atcgtgaaaa atagcggaga
    10861 tgccaaactg aatgtggaac gcaaaggcaa ggtagcccgt gttttcctca aagaaaatgg
    10921 ggaaacagta gcttggaaca tttttgaggt ttcgagcttg tttgaaattg cagagcgcgg
    10981 tcaagtcttt ttatcagatg agcaagtcgc tcgtttgaac caagaattac aggcggaagg
    11041 ttttacagaa gaaattgtta atgataagga acctaagttt gttgttggtg aaattgtcga
    11101 gatggtagct catccagaca gtgaccacct caacatctgc caagttgcag tcgcaagtga
    11161 caagatagtg caaatcgttg caggagcacc taatgcgcgt gttgggttga aaaccattgt
    11221 ggctcttcct ggtgccatga tgccaaaagg gaatttcatt ttcccaggcg aacttcgtgg
    11281 tgaaaagagt tttgggatga tgtgtagtcc tcgtgaattg catttgccaa atgctccgca
    11341 aaaacgtggg gtgcttgaat tatcagaaga ccaagttgtc ggaacaccgt tcgacccagc
    11401 gaaacactgg actgcctagg aacttgtcag catctgatag aaggaaataa gatggcaaaa
    11461 aatgtagtga ttacgggagc aacctcagga atcggtgaag cgattgcgcg tgcttatctg
    11521 gagcagggtg aggatgtcgt tctaacagga cgacggatag acagattaga aatcctcaag
    11581 tcggagtttg cagtaagctt tccaaatcaa accgtctgga cttttccact agatgtgacg
    11641 gatatggtca tggtgaagac tgtttgctct gatattctag aaacgatagg gaggattgat
    11701 atcttggtca acaacgccgg actggctctt gacttggctc cctatcaaga ctatgaggag
    11761 ttggatatgt tgaccatgtt ggataccaat gttaaaggtc tgatggcggt tactcgctgt
    11821 ttcttgccag caatgataaa agtcaatcaa ggtcatatta tcaatatggg gtcaaccgca
    11881 ggaatctacg cctatgctgg tgccgctgtt tactcagcta ccaaggctgc ggttaagacc
    11941 ttttcggatg gactgcgaat tgataccatc gcaacggata tcaaggtgac aaccattcag
    12001 cctgggattg tcgaaacaga tttctcaact gttcgttttc atggtgataa agagcgagct
    12061 gcgtccgttt accaaggaat agaagccttg caagctcagg atattgcaga cacagtagtc
    12121 tatgtgacca gtcagcctcg ccgtgttcag attacagata tgaccattat ggccaatcaa
    12181 caggcgacag gtttcatgat tcataaaaaa taagaaattt cctcgaaaag ttacaaattt
    12241 ctgtaacttt ttttgatttc ctacgaatag ataagtagga ggaagaaaat atgtataata
    12301 aagttatcat gattgggcgt ttaacgtcta caccagaatt gcacaaaacc aacaatgaca
    12361 agtcggtagc gcgagcaact atcgctgtga accgtcgtta caaagaccaa aacggtgaac
    12421 gtgaagctga ttttgtcaat atggtcctat ggggcagact agcagaaact ttggcaagct
    12481 acgcaaccaa aggtagtctc atttccgttg atggagaatt gcgtacccgt cgctttgaga
    12541 aaaatggcca aatgaactac gtgaccgaag tacttgtaac aggattccaa ctcttggaaa
    12601 gtcgtgctca acgtgccatg cgtgaaaata atgcaggcca agatttggca gatttagtct
    12661 tggaagagga agaattgcca ttttaatact cttcgaaaat ctcttcaaac cacgttagct
    12721 ttatccacaa catcaaagca atgctttgag cagcctgcgg ctagcttcct agtttgctct
    12781 ttgattttca ttgagtataa acattaaaaa gtctgagttg gtctcaggct ttttatcttg
    12841 agaaagtcag acttttttct tgattatttc tgactaagtg atacaataga actatgaatt
    12901 agcactcagg tataaagagt gctaataata tctatctcat tatggaggaa atcagatgtt
    12961 gaaaccatta ggggaccgtg tggtcttaaa aatagaagaa aaagaacaaa ccgttggggg
    13021 ctttgttctc gcaggttcag cccaagaaaa aaccaaaaca gcccaagttg tggctactgg
    13081 acaaggtgtt cgtaccttga acggtgactt ggttgctcca agtgttaaaa ctggagaccg
    13141 tgtcttagtt gaagcccacg caggtcttga tgtcaaagat ggcgatgaaa agtacatcat
    13201 cgtaggcgaa gctaacatct tggcaatcat tgaagaatag aaggagaaag taagtatgtc
    13261 aaaagaaatt aaattttcat cagatgcccg ttcagctatg gtccgtggtg tcgatatcct
    13321 tgcagacact gttaaagtaa ccttgggacc aaaaggtcgc aatgtcgttc ttgaaaaatc
    13381 atttggctca ccattgatta ccaatgacgg tgtgactatt gccaaagaaa tcgaattgga
    13441 agaccatttt gaaaatatgg gtgctaagtt agtatcagaa gtagcttcta aaaccaatga
    13501 tatcgcaggt gacggaacta cgactgcaac agtcttgacc caagctatcg tccgtgaagg
    13561 aatcaaaaac gtcacagcag gtgcaaatcc aatcggtatt cgtcgtggga ttgaaacagc
    13621 agttgccgca gcagttgaag ctttgaaaaa caacgccatc cctgttgcca ataaagaagc
    13681 tatcgctcaa gttgcagccg tatcttctcg ttctgaaaaa gttggtgagt acatctctga
    13741 agcaatggaa aaagttggca aagacggtgt catcaccatc gaagagtcac gtggtatgga
    13801 aacagagctt gaagtcgtag aaggaatgca gtttgaccgt ggttaccttt cacagtacat
    13861 ggtgacagat agcgaaaaaa tggtggctga ccttgaaaat ccgtacattt tgattacaga
    13921 caagaaaatt tccaatatcc aagaaatctt gccacttttg gaaagcattc tccaaagcaa
    13981 tcgtccactc ttgattattg cggatgatgt ggatggtgag gctcttccaa ctcttgtttt
    14041 gaacaagatt cgtggaacct tcaacgtagt agcagtcaag gcacctggtt ttggtgaccg
    14101 tcgcaaagcc atgcttgaag atatcgccat cttaacaggc ggaacagtta tcacagaaga
    14161 ccttggtctt gagttgaaag atgcgacaat tgaagctctt ggtcaagcag cgagagtgac
    14221 cgtggacaaa gatagcacgg ttattgtaga aggtgcagga aatcctgaag cgatttctca
    14281 ccgtgttgcg gttatcaagt ctcaaatcga aactacaact tctgaatttg accgtgaaaa
    14341 attgcaagaa cgcttggcca aattgtcagg tggtgtagcg gttattaagg tcggagccgc
    14401 aactgaaact gagttgaaag aaatgaaact ccgcattgaa gatgccctca acgctactcg
    14461 tgcagctgtt gaagaaggta ttgttgcagg tggtggaaca gctcttgcca atgtgattcc
    14521 agctgttgct accttggaat tgacaggaga tgaagtaaca ggacgtaata ttgttctccg
    14581 tgctttggaa gaacctgttc gtcaaattgc tcacaatgca ggatttgaag gatctatcgt
    14641 tatcgatcgt ttgaaaaatg ctgagcttgg tataggattc aacgcagcaa ctggcgagtg
    14701 ggttaacatg attgatcaag gtatcattga tccagttaaa gtgagtcgtt cagccctaca
    14761 aaatgcagca tctgtagcca gcttgatttt gacaacagaa gcagtcgtag ccaataaacc
    14821 agaaccagta gccccagctc cagcaatgga tccaagcatg atgggcggga tgatgtaagc
    14881 attctataga aaacaactta taaaaaacac aaaaggaggg aatgactaac ccttcttttt
    14941 ataatattca cttctaaatt gatttgagct ctcctaactt atatgataaa ataagactag
    15001 aaaaaggaga agaacatgat cgatgtagaa aaaattctgt gcaagatgcc ccccaatcag
    15061 aagattaatt atgaccgtgt catgcagaaa atggtagaag tatggtagaa aaatgagcaa
    15121 cggccaacca ttctcgtgca tgtttgctgt gccccttgta gtacctatac actagaatat
    15181 ttgaccaagt atgcagatgt gaccatctat tttgccaatt ctaatatcca tcccaaggta
    15241 gaataccata agcgggtcta tgtcaccaag aaatttgtta gtgattttaa tgagcggaca
    15301 ggaaatacgg ttcagtacct agaagctccc tacgaaccca attaataccg aaaactagtt
    15361 aggggactag aggaggagcc cgaaggtggc gaccgttgca aggtttgttt tgactaccga
    15421 ctggataaaa cagcgcaagt ggctatggac ttgggctttg actactttgg ttcagccttg
    15481 accatcagtt ctcataagaa ttctcaaacc atcaacagca tcggaatcga tgtgcaaaaa
    15541 atttacacga cccactatct tcccaacgat ttcaagaaaa atcaaggcta caaacgttca
    15601 gtagagatgt gtgaggagta tgatatctat cgtcaatgtt attgtggctg cgtctatgca
    15661 gcccaagccc agaatattga cctggttcaa gttaagaagg acgctacagc attcttgttg
    15721 ggtaaggatg ttgagaaaga ctattctcat atcaaattta tagta
//
LOCUS       DAVBNN010000047        14761 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBNN010000047 DAVBNN010000000
VERSION     DAVBNN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.047"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            83..880
                     /locus_tag="VQ847_001571"
     CDS             83..880
                     /locus_tag="VQ847_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3050884.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VQ847_001572"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VQ847_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VQ847_001573"
     CDS             2383..3657
                     /locus_tag="VQ847_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3050885.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VQ847_001574"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VQ847_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3050886.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VQ847_001575"
     CDS             4786..5088
                     /locus_tag="VQ847_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3050887.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VQ847_001576"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VQ847_001576"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3050888.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VQ847_001577"
     CDS             5962..7302
                     /locus_tag="VQ847_001577"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3050889.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VQ847_001578"
     CDS             7280..7492
                     /locus_tag="VQ847_001578"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3050890.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VQ847_001579"
     CDS             7489..8364
                     /locus_tag="VQ847_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3050891.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VQ847_001580"
     CDS             8357..9172
                     /locus_tag="VQ847_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3050892.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VQ847_001581"
     CDS             9165..9596
                     /locus_tag="VQ847_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3050893.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VQ847_001582"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VQ847_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3050894.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VQ847_001583"
     CDS             11272..12000
                     /locus_tag="VQ847_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3050895.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VQ847_001584"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VQ847_001584"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3050896.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VQ847_001585"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VQ847_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14360..>14761
                     /locus_tag="VQ847_001586"
     CDS             14360..>14761
                     /locus_tag="VQ847_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3050897.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGN"
BASE COUNT         4394 a         2673 c         3484 g         4210 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ttcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagttatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt tgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gcattggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggccatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttag ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa tgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggccgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgct aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccagaatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaaacggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtttatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgaaacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccat ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccatttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aaatacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aatcatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
    14281 agaatagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    14341 ggaaagaagg gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
    14401 cttagaagcg gataatcaag aacaactctt tgatcaggta gcaagcttgt tggaagaacg
    14461 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
    14521 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcacacaga
    14581 tattgttcat aatctagctg aaaaagtggt ggttgttcga ttagaaaaac cagtaacttt
    14641 tcacaatatg attgcgccag gtaaggaagt agaagtatcc ctactcttct ttatcattaa
    14701 caattcaagt tcaagtcaaa caaatattct ggctcagttg atggactttt tcacaggaaa
    14761 t
//
LOCUS       DAVBNN010000048        14491 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBNN010000048 DAVBNN010000000
VERSION     DAVBNN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14491
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.048"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ847_001587"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ847_001587"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3050898.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ847_001588"
     CDS             1085..2809
                     /locus_tag="VQ847_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050899.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ847_001589"
     CDS             2811..4559
                     /locus_tag="VQ847_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3050900.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ847_001590"
     CDS             4816..6075
                     /locus_tag="VQ847_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3050901.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ847_001591"
     CDS             6325..6825
                     /locus_tag="VQ847_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3050902.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ847_001592"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ847_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3050903.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ847_001593"
     CDS             7456..7629
                     /locus_tag="VQ847_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050904.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ847_001594"
     CDS             7626..8222
                     /locus_tag="VQ847_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3050905.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ847_001595"
     CDS             8259..8396
                     /locus_tag="VQ847_001595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050906.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..9894
                     /gene="dcm"
                     /locus_tag="VQ847_001596"
                     /pseudo
     CDS             8495..9894
                     /gene="dcm"
                     /locus_tag="VQ847_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            9878..10327
                     /locus_tag="VQ847_001597"
     CDS             9878..10327
                     /locus_tag="VQ847_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050907.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            10320..10700
                     /locus_tag="VQ847_001598"
     CDS             10320..10700
                     /locus_tag="VQ847_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050908.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
     gene            10713..10946
                     /locus_tag="VQ847_001599"
     CDS             10713..10946
                     /locus_tag="VQ847_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3050909.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            10949..11536
                     /locus_tag="VQ847_001600"
     CDS             10949..11536
                     /locus_tag="VQ847_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3050910.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILEILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            11666..12256
                     /locus_tag="VQ847_001601"
     CDS             11666..12256
                     /locus_tag="VQ847_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3050911.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            12256..13092
                     /locus_tag="VQ847_001602"
     CDS             12256..13092
                     /locus_tag="VQ847_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET3050912.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIDIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AKKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
     gene            13375..13593
                     /locus_tag="VQ847_001603"
                     /pseudo
     CDS             13375..13593
                     /locus_tag="VQ847_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13893..14180)
                     /locus_tag="VQ847_001604"
                     /pseudo
     CDS             complement(13893..14180)
                     /locus_tag="VQ847_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14179..14442
                     /locus_tag="VQ847_001605"
                     /pseudo
     CDS             14179..14442
                     /locus_tag="VQ847_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4566 a         2539 c         3048 g         4338 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgatcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcactt gcaggaagac gattgggatt
     8761 tgaagatact agaggaactt tgttctttga aattgctcgg gcggccaaac aaatccaacc
     8821 acgttttctt tttcttgaaa atgttaaagg cctactcaat cacgataagg gacggacgtt
     8881 caccacaatc cttaccacat ttgatgagtt ggggtttgat gttgagtggc aggtgcttaa
     8941 cagtaaggat tttggcgttc cccaaaacag agagagggtg tttattatcg gacattctag
     9001 aaagaaaggt accagactct tatttccttt cagacgagaa ggtcaagcaa ctaactctga
     9061 gactttgaaa gcactaggaa atttgaatcc atcaaaaagt ggcgtgagcg gtaaagtgta
     9121 ttattcagaa ggtcttgcgc caactttagt tcgtggaaaa ggagaaggat ttaaggttgc
     9181 tattccttgt atgacaccag atagattaga caaaagacaa aatggtagac gctttaagga
     9241 aaaccaagag ccgatgttta ctttaaatac tcaggatcgt catggcattg tcgttgttgg
     9301 agatttaccg actagtttta aggagacagg tcgtgtctat ggaagtgagg gcttatctcc
     9361 aacactgact acgatgcaag gaggagataa aatccccaaa atactaattc cagaaccaat
     9421 ccaatttcta aaagtacggg aagcaacgaa aaaaggatat gctcaagcag agattgggga
     9481 ttcaatcaat ttggaaagac caagttctca gtatcgtcgt ggtagagttg gcaaaggtat
     9541 agctaatacg ttaacaactg tggtagagtt ggcaaaggta tagctaatac gttaacaact
     9601 agtggtcaaa tgggagtagt agtggctagc tatgaaggag aagataaaca agtttaccaa
     9661 gtagctggtg ttttaataga tggacaattt taccgtttga gaatacgacg aatcactcct
     9721 aaagagtgtt ttcgattgca tggctttcct gattgggctt ttgaagctgc tagaaaagtc
     9781 tctagtaata gtcagctcta taaacaagct ggtaatagtg taaccgttcc tgtgattgcc
     9841 gcaatcgcaa agaaattaaa agaaatagag gaaaaagatg aaagcattaa ataaagaatc
     9901 aatactagat tgtgatgaat tagaaacaga attacatgat gcagaaatca aacagctgga
     9961 tgaacaatta tttttgatgc ccaattatcc atgtgagttt gaagtaacat ttttagatga
    10021 ttaccataaa aaacacaact acccactatt ttacgagtcc tatcttcaaa acgttatgga
    10081 attccttgaa agtcaagaca taaagaatgg ggttgatgcc tttgtagatg atcatcaaaa
    10141 tctcgttttt gttttatatg gacaaggcta tcgagcagag ggaaaagagg gaatacttac
    10201 aactcaagta actgtaaaag cttatgatga agacaagaaa ccgattaact tcgcaaattt
    10261 attagattcc ttaatcgtct cagaatatca aatggaaccg aatctttgga aggtctccca
    10321 tgattgatct ctatctaagt aaaaatagcc aaagaaatca acttcttttg gatttctttc
    10381 aaaagtatgg catagaggtc actcctcatt ctatttctga aatgacaaag gacaaattaa
    10441 ttgaaatgat gagctattct tcagattgtt ttgagtttct atctcccaat ttattacgat
    10501 ttaagaaccg tgacaatcta agattaacgg atttcattga aatgatatta aaaaatcctg
    10561 aactatgcat caggcttcct cttgcggttt caaataagag agtttatcca aatctgaatt
    10621 tggaagaggc tagagctcta ttgccaagag atacgaaaca attgatttac atggcacaaa
    10681 cacattattt atctagttaa aggagaagca atatggctga acgattttgg gagaacttgt
    10741 ccattatttt ggctgaaaga aatattagct ggattgagtt aaccagaaaa atgtttgcgg
    10801 gagagtttca ctatccaagt gaattgaatc gtttgtatca aaagatacgc cactacaaga
    10861 tggaacaacg aatgcctcaa agtccatggg tagaaaggat tgtgcaggta ttagatttag
    10921 attatgaaga tttatttcgg aggtaactat gaaaagaata attccagttt atatattcca
    10981 acaagtaaat gtcttattgg tatccctata cttactgaaa ttgctttgta ttggtgagtt
    11041 aaccatacta gagattctct attgtgcgtc gctcatttct tttttatgga tgtatggtca
    11101 acgaaaacaa gtggtcaagg tcaatatgaa aactaggatg aaatggcttg gtattggatt
    11161 tgttagccta ctgattataa gtctatgttt tagtctgatt catgctcaag gaaccacgaa
    11221 tcaagcaaac ttaattggcc ttcaacatca ggttccttgg ttttcatttt tattgttctt
    11281 aatcaatgcg agtatggttg aagaatttct gtatcgagaa attttatgga acttggtcag
    11341 aaaattagat attcgagttg ctttgacaag tgttttattt gccttagtac atcatccagg
    11401 aaccattcta gcttggtgtt tatatgtttc acttgggatc tttttaggga tggtgcgcta
    11461 taaatcggac ttatggggaa gtatgggtct acatttggtg tggaacctat cagtctatgt
    11521 cttatttttt ctttaataat agctggtctg tcttacgtat ggattaattt tgaaataaaa
    11581 aaactaaatg aattgatttt aaagaaataa aatgctaaca tatatagaag atgttagcat
    11641 tttatttcta agaaaggaga atggtatggt tgataaaaga gagaaactga tgaactcttt
    11701 caatcagtat ggttttttaa cttttaaaca agtaatagat gaaaatttac actacaaaac
    11761 cttattaaaa atggttacag aaggaaaaat cgatgctgaa gaaaaagggt tatatcgctt
    11821 acctgatatt tatttagatg agtggtttgt cattcagtat cgatttccaa aaggaatctt
    11881 ttctttggag acagcacttt ggttacatgg tttatctttg actatccctt ttaacatgac
    11941 aatgagtttt ccttatggta cgaataccaa aaacattaag gaagcagata tatgtcctat
    12001 tatcttacgc tctcactata gtgaaggaat tattgaaata gagcgtcttc ctggtcaatt
    12061 tattaaagtt tatgaaattg aacgagtttt ggttgaatgt ctaagaccag ttcatcaggt
    12121 ggatcttcaa attattgcac cagcgtttaa gaaatatttt caacagaatc aaattcattt
    12181 acacaaatta ttttattatg cccaactatt taaagtaact gataagttac aatcttatac
    12241 ggaggtgcta tcttaatgtt ttcaaatgcg aatagcttta aagcaaaaat caaaaatatt
    12301 tcaaaagata agggaattcc agctcaacaa gtacaacaac attatttaat tgagcaagtg
    12361 ttaaagctga tttctactag ttcttataga gattccttca ttgtaaaagg agggtatcta
    12421 ataggtcaaa tgattggact agataagcga accacaatgg atttagatgt cactctgaag
    12481 ggaaccgaaa tgagcagaga aaatttgatt gatatctttg aagagattct ttgttctaaa
    12541 actgatggtt tttcattttc agtagataag ctagaaccta ttcgccaaga tgatgaatat
    12601 ggaggatttt cattaaaatt aaatgcaact tttgatacat taaaggaggt tgtttttatt
    12661 gatattacta ctggtgataa gatcacacca agagaaatta cttattcaat gacttctatc
    12721 tttactaatg aaagcatcaa gatatggaca tataatttag agactgtact tgctgaaaag
    12781 ttagaaacaa tcattagtag gggattagct tcaacacgcc cacgtgatcg atatgatctt
    12841 ttcaccttgt ataaacttag aaaagaagag attaatcttg aagtattaaa aaatgcactt
    12901 gaaaatacag caaaaaaacg taaaagtaaa gatactattt ataattggga agaacaagtg
    12961 agaggaattg aaatttctga ttatcagaaa gagctatgga ttcgttatca acgccaattt
    13021 aagtatgcta aagatatctc atttgataac tctgttcagg ttattaggga aattatgcaa
    13081 caaatatttt agtacaaaag taactcattc gtaaagcagt gagttgcttt ttttattcca
    13141 acaacctcaa acatgtgata aaaatttcaa ctactcttat ctataataaa gctacctgtt
    13201 ctttgaaaat tgaatccact ccgtcttgat tagcgtgcct gtgtaagtag ggaatgagag
    13261 tatttccctg tgaagggcaa ctggcacaag acgtgtgtga gaattttcta acagacacgg
    13321 agtttatcgt ttccagactc aaacgatgcg acaaactaga taaaggagtt aatcatgaag
    13381 gtagtaaact tgtatgattt gaaacaaatg ggaaataaag gtggttgtac catccaattg
    13441 attcatcact ttccttttgg tatgggctta ggacatctca aaaaagacta cattgaattt
    13501 aaacgtgttg gtatctttga tgggaaagca gtagaagtta ctcttcgaga accttattcg
    13561 agagatctac tgcaggttgt caagtcaata aagtaactga caccacgagt ataattatta
    13621 gaaacgtgga atcttattaa attttataat aaatatatta aatgaaaaat tattagatat
    13681 aaacttatgt aataaaacat tgaggaaata ataaaaatct atgggtaatg ttctgaaagt
    13741 acttttaggt taggagagaa atataatgat ttttgaaaat tgattcaaaa aatagcgaat
    13801 tgtagaaaac gcttaacaaa tggtgtataa tagacttcca gcgaaacaaa atatgctaca
    13861 ataaacctat gaattataaa gtaaccttat actcatctgt cttcacaaag cattctagtc
    13921 catctccgat taacgatgga ctttatcatc tccttctcca gtccttgtat gacatcttcc
    13981 aaagttcgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca cacttattca
    14041 atggggttca tttctggtgt gtatggagga ataaatgcaa agccaatatt agtcggaatc
    14101 tttaaggcac ttgatttatg ccatatagca ttgtccataa cgaataaaag ataatcatct
    14161 ggataagctt gtgaaagctt ggctgacagt ggttatcaag ggctcatgaa gatatatctt
    14221 caagcacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagctga agataaagcc
    14281 tataaccatg cgctatctaa ggagagaagc aaggttgaga atatttttgc caaagtaaaa
    14341 acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg
    14401 aatttgattg ctgatattat caatcatgaa ctaggattct agttttgcag gaagtctaat
    14461 aaatgtataa gaaaaaggag gaaaaaggat g
//
LOCUS       DAVBNN010000049        14344 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBNN010000049 DAVBNN010000000
VERSION     DAVBNN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.049"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(83..646)
                     /locus_tag="VQ847_001606"
     CDS             complement(83..646)
                     /locus_tag="VQ847_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3050913.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ847_001607"
     CDS             complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ847_001607"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3050914.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ847_001608"
     CDS             complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ847_001608"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3050915.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2112..3782
                     /locus_tag="VQ847_001609"
     CDS             2112..3782
                     /locus_tag="VQ847_001609"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3050916.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4110..5285
                     /gene="mutY"
                     /locus_tag="VQ847_001610"
     CDS             4110..5285
                     /gene="mutY"
                     /locus_tag="VQ847_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3050917.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5341..6045
                     /locus_tag="VQ847_001611"
     CDS             5341..6045
                     /locus_tag="VQ847_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3050918.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6038..7387
                     /gene="vicK"
                     /locus_tag="VQ847_001612"
     CDS             6038..7387
                     /gene="vicK"
                     /locus_tag="VQ847_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3050919.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7389..8198
                     /locus_tag="VQ847_001613"
     CDS             7389..8198
                     /locus_tag="VQ847_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3050920.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8289..8531
                     /locus_tag="VQ847_001614"
     CDS             8289..8531
                     /locus_tag="VQ847_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3050921.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8533..8787
                     /locus_tag="VQ847_001615"
     CDS             8533..8787
                     /locus_tag="VQ847_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3050922.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8834..9577
                     /locus_tag="VQ847_001616"
     CDS             8834..9577
                     /locus_tag="VQ847_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3050923.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(9867..10853)
                     /locus_tag="VQ847_001617"
     CDS             complement(9867..10853)
                     /locus_tag="VQ847_001617"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3050924.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ847_001618"
     CDS             11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ847_001618"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3050925.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            13515..14258
                     /gene="srtA"
                     /locus_tag="VQ847_001619"
     CDS             13515..14258
                     /gene="srtA"
                     /locus_tag="VQ847_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3050926.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4394 a         2476 c         3188 g         4286 t
ORIGIN      
        1 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
       61 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
      121 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
      181 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
      241 caaagatagt atttgtcaag gaaccaagag ccccagctaa aatcagacca gtcttgtttt
      301 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acaatggcaa
      361 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
      421 gaatcgtaat cgtgttaacc gtcaagctaa gtaatcccat caaaaatcca agtgtaaccc
      481 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
      541 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
      601 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgag agtttccttt
      661 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
      721 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
      781 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
      841 atatgacttg gtagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
      901 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
      961 agttcgatat gattgacctg atcaggatag ggttccttca tgacatccaa gtggacagga
     1021 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
     1081 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
     1141 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
     1201 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
     1261 gaagctgatt tttctcaaca aatatagctc ggtgctgatc tgctgaaatt tgagtcaggt
     1321 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
     1381 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
     1441 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
     1501 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
     1561 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
     1621 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
     1681 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
     1741 tcgtaattaa acaaacttca tgccctgcag aaagcaaagt ctctgtgata attttcccca
     1801 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
     1861 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
     1921 aaagtgataa atttttggta aaaacgaaga tttattatag tttcaaacta taaagccata
     1981 taaaatttaa gaaaggactc taaaagtctt aaaaacagag atatttacga acgtttagag
     2041 agttttagga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
     2101 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
     2161 ttgatgttgt agagaaactt ggtatttctt atgacgattt ggagttgtac ggaaagtaca
     2221 aggctaaact cagctttgat aaaattcgtg cagttgagag caatccagtc ggtaaattga
     2281 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgacg cttaccattg
     2341 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
     2401 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
     2461 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
     2521 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctgggaattg
     2581 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
     2641 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggacggt tttgatatta
     2701 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
     2761 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
     2821 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
     2881 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
     2941 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
     3001 ctgaagctgg ttttggtgcg gatcttggtg ctgagaaatt ccttgatatc aagacaccaa
     3061 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
     3121 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
     3181 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
     3241 ctattaacga atttgtatct gatacagaag ctgaaattgc agtcttaaaa gaactctgtg
     3301 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
     3361 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
     3421 tgtacgataa tgatctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
     3481 gtggtagcaa agtgaacttt gagaagaaag ctcaaacaca aattgctcaa atcgttcaaa
     3541 acggttggga caaattgcca atttgtatgg ctaaaactca atacagtttc tcagacaatc
     3601 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
     3661 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
     3721 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtgcta ggcttgttct
     3781 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
     3841 gactgcaagc agttcatcaa taagatttat actcttcgaa aatcttttca aactacgtca
     3901 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
     3961 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     4021 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
     4081 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
     4141 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
     4201 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
     4261 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga tttttggact
     4321 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
     4381 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
     4441 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
     4501 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
     4561 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
     4621 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatcca gatcgtccgg
     4681 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
     4741 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
     4801 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
     4861 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
     4921 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
     4981 tctttcatca ggttgcggaa gaaagtgtga actctggccc cagtccagaa gagagtttcc
     5041 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
     5101 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
     5161 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
     5221 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
     5281 actagctatt gtgtcttctg actatttttt tggtataata gtagagaaaa aggtgaacat
     5341 atgaaaaaaa tactaattgt agatgatgag aaaccaatct cggatattat caagtttaat
     5401 atgaccaagg aaggttacga agttgtaact gcttttaatg gtcgtgaagc gctagagcaa
     5461 tttgaagcag agcaaccaga tattattatt ctggatttga tgcttccaga aattgatggt
     5521 ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc ccattcttat gctttcagcc
     5581 aaagatagtg aatttgataa ggttatcggt ttggaacttg gggcagatga ctatgtaacg
     5641 aaacccttct ccaatcgtga gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa
     5701 cctatgccag tagatggtca ggaagcagat agtaaacctc aacctatcca aattggggat
     5761 ttagaaattg ttccagacgc ctacgtggct aaaaaatatg gcgaagaact agacttaacc
     5821 catcgtgaat ttgagctttt gtatcattta gcatcgcata caggtcaagt catcacgcgc
     5881 gaacacttgc ttgagactgt ctggggttat gactattttg gtgatgtccg tacagttgat
     5941 gtgactgtac gacgtctgcg tgagaagatt gaagatacgc ccagccgacc agagtatatc
     6001 ttgacacgcc gtggtgtagg gtattacatg agaaataatg cttgatttac tgaaacaaac
     6061 catttttacc agagatttta tctttatcct gattttgtta ggtttcatcc ttgttgtgac
     6121 cctcttatta ctggaaaata gacgtgataa tattcagttg aagcaaatca atcaaaaggt
     6181 taaagatttg attgcaggag attattccaa ggttcttgat atgcaaggtg ggtctgaaat
     6241 caccaatatt accaataatt tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa
     6301 tctagaacaa gagagtaaga ggctaaatag tattctgttt tatatgacag atggggttct
     6361 tgcgaccaac cgtcggggtc agattatcat gattaacgat acagccaaga agcaactggg
     6421 gttggttaag gaagatgttc tgaatagaag cattttggaa ttgctcaaga tagaagaaaa
     6481 ctatgaattg cgtgatttga ttacccaaag tccagaattg ttgctagatt cccaagatat
     6541 aaatggtgaa tatttgaacc ttcgagttcg ctttgccttg atacgtcgag agtctggctt
     6601 tatttcaggt ttggtggctg ttttgcatga tacgacggag caggagaagg aagaacgcga
     6661 acgaagactc tttgtttcca atgttagcca tgagttacgg actcctctga ctagcgtaaa
     6721 atcctatctt gaagccttgg atgagggggc tttgtgtgaa actgtagcac cagactttat
     6781 caaggtttct cttgatgaga ccaaccgtat gatgcgcatg gtgacggatc tcctccatct
     6841 ttcacgtatt gataatgcta ccagtcacct agatgtggaa ctgattaact tcactgcttt
     6901 tattaccttt atcctcaatc gttttgacaa gatgaaagga caggaaaagg agaaaaaata
     6961 tgagttggtg agagattatc ccatcaattc tatctggatg gaaattgata cagataagat
     7021 gacgcaggtt gtcgacaata ttttaaataa tgctattaaa tattcgccag atgggggtaa
     7081 aatcactgtc agaatgaaga caactgaaga ccagatgatt ttatccattt ctgaccacgg
     7141 tttggggatt cctaagcagg atttaccacg tatctttgac cgtttctatc gtgtggatcg
     7201 tgctagaagt cgtgcacaag gtggtacagg tctaggactg tctatcgcta aagaaattat
     7261 caaacaacat aagggcttta tttgggccaa gagtgaatac ggcaagggtt caacctttac
     7321 cattgtgctc ccttatgata aggatgcagt gaaagaagaa gtatgggagg atgaagtaga
     7381 agactagaat gagtgaaata ggctttaaat acagtatttt agcgtcgggt tccagtggaa
     7441 attcttttta tctggaaacc tcaaaaaata agcttttagt agatgcaggc ttgtctggca
     7501 agaaaattac cagtctgcta gctgaaatta accgtaagcc agaagacctg gatgccatct
     7561 tgattaccca tgagcattca gatcatatcc atggagtagg cgttttggct cgcaagtatg
     7621 gtatggatct ttatgccaat gaaaagacct ggcaagctat ggaaaatagt aaatatcttg
     7681 gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg taaaaccaaa acctttggag
     7741 atatcgacat cgagagtttt ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct
     7801 ttatgaagga tgataagagt tttgtccttt tgacagatac aggttatgtc agtgaccgta
     7861 tggcgggcat tgtcgaaaat gcggatggct atcttatcga ggccaaccat gatgtagaga
     7921 ttttgcgatc aggttcttac gcttggcgac tcaaacaacg aatcctatct gaccttggtc
     7981 acctttctaa cgaggacggt gctgaagcta tgattcggac gctaggaaat cgtactaaga
     8041 agatttacct tgggcattta tctaaggaaa ataatatcaa ggaactggct catatgacca
     8101 tggtcaatca gctggctcaa gctgatctgg gagtcggagt agactttaag gtttatgata
     8161 cctcaccaga taccgcaaca ccattgacag agatataaaa agaacgctga gaaggtgttc
     8221 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
     8281 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
     8341 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
     8401 ccctagaaga tgaatacgat gctcgtgtgg caaatttagc ctatcaagag tatttagaag
     8461 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
     8521 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
     8581 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaaggc
     8641 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
     8701 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
     8761 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacaata tagaaagtaa
     8821 ggagagtaaa aatttgaaga aaaaatgctt ttttgcagat tattatgata caacaattat
     8881 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgattgattt
     8941 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
     9001 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
     9061 tttattggct attctccctt taaatgctat tttcacagtt tttcgattag ggcgtatctt
     9121 tcgtttagtt aaactaacaa aattactgaa actgactcgt ttacttagaa taattggact
     9181 tataggtaaa ttagaaagaa aaattagtag attcttacgg acaaatggcc tgatttatat
     9241 cttatatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     9301 aaaatccttc tcagatagtc tctggtgggc tcttgtgacg gtaactactg ttggttatgg
     9361 tgatgttgtt cctacttcaa tttttggtaa atggttagct gtcttattaa tgcttgtcgg
     9421 tattgggaca ataggaatgt taacgagtac cttgacgaac ttttttgtaa aggataatcc
     9481 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagccaaa gaatattaat
     9541 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     9601 aatatcataa aggtgagaca aaacaaaact tgattcgagg agaaatcaag taagtcttga
     9661 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     9721 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     9781 tgatagggtg ctatttcaac ttcaacctac tataatacag aaaaaaaaca actccctgat
     9841 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     9901 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     9961 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
    10021 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
    10081 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
    10141 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
    10201 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
    10261 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
    10321 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
    10381 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
    10441 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
    10501 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
    10561 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
    10621 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
    10681 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
    10741 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
    10801 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
    10861 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
    10921 aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt ggtttagagg
    10981 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
    11041 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
    11101 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
    11161 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
    11221 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
    11281 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
    11341 atgcttgtag atggtcacgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
    11401 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
    11461 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
    11521 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
    11581 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
    11641 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
    11701 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
    11761 gccctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
    11821 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
    11881 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
    11941 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
    12001 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
    12061 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
    12121 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
    12181 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
    12241 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
    12301 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
    12361 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
    12421 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
    12481 aagcgccgta cagagttgat gattggacag gtcttgagtc tcgaggatga ggacttgatt
    12541 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
    12601 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
    12661 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
    12721 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
    12781 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
    12841 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
    12901 attgtgaaga gaaccagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
    12961 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
    13021 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
    13081 atgagtcgta tcgccactgg tgtaaaaggt gttaaccttc gtgaaggaga cacagttgtt
    13141 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
    13201 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
    13261 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
    13321 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
    13381 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
    13441 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
    13501 gaaggtgaag aataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
    13561 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
    13621 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
    13681 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
    13741 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
    13801 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
    13861 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
    13921 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
    13981 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
    14041 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
    14101 gagatggggt caatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
    14161 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct gatgaaattc
    14221 taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg aaatcatgga
    14281 tttcactgat tttttaagat tttcataaaa atatagtaaa atgaaataag aataggacga
    14341 atcg
//
LOCUS       DAVBNN010000050        14208 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBNN010000050 DAVBNN010000000
VERSION     DAVBNN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.050"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ847_001620"
     CDS             <1..211
                     /locus_tag="VQ847_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050927.1"
                     /translation="PRKSSKLKPLTVEDQAYNHALSKERSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(526..2217)
                     /locus_tag="VQ847_001621"
     CDS             complement(526..2217)
                     /locus_tag="VQ847_001621"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3050928.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2353..2799
                     /gene="argR"
                     /locus_tag="VQ847_001622"
     CDS             2353..2799
                     /gene="argR"
                     /locus_tag="VQ847_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3050929.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2850..5384
                     /gene="mutS"
                     /locus_tag="VQ847_001623"
     CDS             2850..5384
                     /gene="mutS"
                     /locus_tag="VQ847_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3050930.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5531..7225
                     /gene="patA"
                     /locus_tag="VQ847_001624"
     CDS             5531..7225
                     /gene="patA"
                     /locus_tag="VQ847_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3050931.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7555..7818)
                     /locus_tag="VQ847_001625"
                     /pseudo
     CDS             complement(7555..7818)
                     /locus_tag="VQ847_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8016..9782
                     /gene="patB"
                     /locus_tag="VQ847_001626"
     CDS             8016..9782
                     /gene="patB"
                     /locus_tag="VQ847_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3050932.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISSPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9921..10610
                     /locus_tag="VQ847_001627"
     CDS             9921..10610
                     /locus_tag="VQ847_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3050933.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10614..10793
                     /locus_tag="VQ847_001628"
     CDS             10614..10793
                     /locus_tag="VQ847_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050934.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10780..12129
                     /locus_tag="VQ847_001629"
     CDS             10780..12129
                     /locus_tag="VQ847_001629"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3050935.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12253..13713
                     /locus_tag="VQ847_001630"
     CDS             12253..13713
                     /locus_tag="VQ847_001630"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3050936.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13727..14161
                     /locus_tag="VQ847_001631"
     CDS             13727..14161
                     /locus_tag="VQ847_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3050937.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4161 a         2749 c         3193 g         4105 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccact aacagttgaa gatcaagcct ataaccatgc
       61 gctatccaag gagagaagca aggtcgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctatta tttggttagg
      241 tgaattagtg aagcgtttag gcaagtgtct ctggttacga cgtcatggcc tctaaatcga
      301 ttatatttag gggtcatgac tagtgaagca gttagctagt tcgcatataa gcggctagcg
      361 tctaacaatt aggaacttta gttccaataa ctttaagatt acgacgtttt aggacataaa
      421 tcgatcatat ttatgtccta aaactagtga agcgcctagc caaagtccga ataggatttg
      481 gcgttagtta cttagattgc tttgcaatca agtaactttg gcgatttaca tcttctctgg
      541 cgcttctact ccaagcaagc gaagggcttc ttttagaacg actgcggttg cgtagctgag
      601 ggctagacgg ctgtcgcgtt ctgggctttc atccaagata cgtgtatgtg catagtattt
      661 gttaaaggat tgagctaggc taattgcaaa tttagcaatg atagaaggtt caaagttatc
      721 tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt ttaatgattt cccagctttc
      781 agtatcattc aagctatagt tgccagctgt ttctggtttg aaatcggctt tgcgtaagat
      841 agattggata cgagcgtagg catattgaac gtaaggtcca gtttcaccct cgaaggatac
      901 catagcttct aggtcgaagt cgtatccatt tgtacggtcg gttttgaggt catagaattt
      961 aatggctcca accccaacag catgtgctac ttggtctttg ttttctagtt caggattttt
     1021 agcctcgatt tggaccttgg cacggctaac agcctctgca acagtaggct ctagcaagat
     1081 gacattccct ttacgagtag agagcttctt cccttccttt gtaaccaaac caaaaggaac
     1141 gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc aagacagctt tgagctgttt
     1201 aaagtgggca gattgttctt gaccaacgac atagatagat ttagcaaatt ggtattcgtt
     1261 tttacggtaa agggctgcag ccaagtcacg tgtgatatag agagttgcac catcagactt
     1321 cttgatgagg gctggatgtt caattccata tttctcaaga ttcacaactt gggcaccttc
     1381 tgattcaaga agtagtcctt tttcagaaag aatgtctaca actgcatcca tcttatcatt
     1441 gtagaaggct tctccgttat agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt
     1501 aaattccact aaactttcat cgcggaacca ttgccaaaga gcgagagctt cctcatctcc
     1561 attttcaagt ttacggaacc attcgcgcgc ttcttcatcc aagctagggt cattttcagc
     1621 ttcagcgttg atgcggacat agagtttaag gagttcatcg attggatgag cttttacagc
     1681 ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc ccaaattgtt taccccagtc
     1741 tcccaaatgg ttgaccttga ccgtttgata accgattttt tggaaaatat gtgacaagct
     1801 atctccgata acagttgaac gcaggtggcc aatagaaaat ggtttagcga tattcggact
     1861 agacatgtcg ataacaacat tttcttgttt gccaatattt tggtcagcat agtgttcttt
     1921 ttcagttgta acagcttgca atacttgagc agaaatggca gatttatcaa ggaaaaagtt
     1981 aacgtaaggt cctgttgcga caactttttc aaaggcttgg ctgttcattt tttcagccag
     2041 ttcagccgca atcatttgtg gtgctttacg ttcgactttg gcaagagaaa aagcagggaa
     2101 agcgatgtca cccatttctg agtttttagg ggtttccagt aactttaaaa tagcctcttg
     2161 gtccaggcta tcaatgatgc tagccaattc gctagcaatc aattcttttg tattcattaa
     2221 gagctccttt ttggactttt ctactatttt aacacaattt taaagaaaga agaaaaaatt
     2281 tttgaaatct cttgtttttt tggtataata tggttataaa tatagttata aatatgcacg
     2341 caagaggatt ttatgagaaa aagagatcgt catcagttaa taaaaaaaat gattactgag
     2401 gagaaattaa gtacacaaaa agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg
     2461 acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat
     2521 gatatggtgt attatgtact agtaaatgag acagaaaaga ttgatttggt ggaatttttg
     2581 tctcatcatt tagaaggtgt tgcaagagca gagtttacct tggtgcttca taccaaattg
     2641 ggagaagcct ctgttttggc aaatattgta gatgtaaaca aggataaatg gattttagga
     2701 acagttgctg gtgccaatac cttattggtt atttgtcgag atcagcacgt tgccaaactc
     2761 atggaagatc gtttgctaga tttgatgaaa gataagtaag gtcttgggag ttgctctcaa
     2821 gacttatttt tgaaaaggag agacagaaaa tggcgataga aaagctatca cccggcatgc
     2881 aacagtatgt ggatattaaa aagcaatatc cagatgcttt tttgctcttt cggatgggtg
     2941 atttttatga attattttat gaggatgcgg tcaatgctgc gcagattctg gaaatttcct
     3001 taacgagtcg caacaagaat gccgacaatc cgatccctat ggcgggtgtt ccctatcatt
     3061 ctgcccaaca gtatatcgat gtcttgattg agcagggtta taaggtggct atcgcagagc
     3121 agatggaaga tcctaaacaa gcagttgggg ttgttaaacg agaggttgtt caggtcatta
     3181 cgccagggac agtggtcgat agcagtaagc cggacagtca gaataatttt ttggtttcca
     3241 tagaccgcga aggcaatcaa tttggcctag cttatatgga tttggtgacg ggtgactttt
     3301 atgtgacagg tcttttggat ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc
     3361 gagaagtggt gttgggttat gacttgtctg aggaagaaga acaaatcctc agccgccaga
     3421 tgaatctggt actctcttat gaaaaagaaa gctttgaaga ccttcattta ttggatttgc
     3481 gattggcaac ggtggagcaa acggcatcta gtaagctgct ccagtatgtt catcggactc
     3541 agatgaggga attgaaccac ctcaaacctg ttatccgcta cgaaattaag gatttcttgc
     3601 agatggatta tgcgaccaag gctagtctgg atttggttga gaatgctcgc tcaggtaaga
     3661 aacaaggcag tcttttctgg cttttggatg aaaccaaaac ggctatgggg atgcgtctct
     3721 tgcgttcttg gattcatcgc cccttgattg ataaggaacg aatcgtccaa cgtcaagaag
     3781 tagtgcaggt ctttctcgac catttctttg agcgtagtga cttgacagac agtctcaagg
     3841 gtgtttatga cattgagcgc ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg
     3901 atctcttgca gttggcgact accttgtcta gtgtgccacg gattcgtgcg attttagaag
     3961 ggatggagca acctactcta gcctatctca tcgcacaact ggatgcaatc cctgagttgg
     4021 agagtttgat tagcgcagcg attgctcctg aagctcctca tgtgattaca gatgggggaa
     4081 ttatccggac tggatttgat gagactttag acaagtatcg ttgcgttctc agagaaggga
     4141 ctagctggat tgctgagatt gaggctaagg agcgagaaaa ctctggtatc agcacgctca
     4201 agattgacta caataaaaag gatggctact attttcatgt gaccaattcg caactgggaa
     4261 atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg
     4321 aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg
     4381 aatacgaaat atttatgcgc attcgtgaag aggtcggcaa gtacatccag cgtttacaag
     4441 ctctagccca aggaattgcg acggttgatg tcttacagag tctggcggtt gtggctgaaa
     4501 cccagcattt gattcgacct gagtttggtg acgattcaca aattgatatc cggaaagggc
     4561 gccatgctgt cgttgaaaag gttatggggg ctcagaccta tattccaaat acgattcaga
     4621 tggcagaaga taccagtatt caactggtta cagggccaaa catgagtggg aagtctacct
     4681 atatgcgtca gttagccatg acggcggtta tggcccagct gggttcctat gttcctgctg
     4741 aaagcgccca tttaccgatt tttgatgcga tttttacccg tatcggagca gcagatgact
     4801 tggtttcggg tcagtcaacc ttcatggtgg agatgatgga ggccaataat gccatttcgc
     4861 atgcgaccaa gaactctctc attctctttg atgaattggg gcgtggaact gcaacttatg
     4921 acgggatggc tcttgctcag tccatcatcg aatatatcca tgagcacatc ggagctaaga
     4981 ccctctttgc gacccactac catgagttga ctagtctgga gtctagttta caacacttgg
     5041 tcaatgtcca cgtggcaact ttggagcagg atgggcaggt caccttcctt cacaagattg
     5101 aaccgggacc agctgataaa tcctacggta tccatgttgc caagattgct ggcttgccag
     5161 cagacctttt agcaagggcg gataagattt tgactcagct agagaatcaa ggaacagaga
     5221 gtcctcctcc catgagacaa actagtgctg tcactgaaca gatttcactc tttgataggg
     5281 cagaagagca tcctatccta gcagaattag ctaaactgga tgtgtataat atgacaccta
     5341 tgcaggttat gaatgtctta gtagagttaa aacagaaact ataaaaccaa gactcactag
     5401 ttaatctagc tgtatcaagg agacttcttt gacaattctc cacttttttg ctagaataac
     5461 atcacacaaa cagaatgaaa aggagctgac gcattgtcgc tcccttttgt ctatttttta
     5521 aggagaaagt atgctgattc agaaaataaa aacctacaag tggcaggccc tggcttcgct
     5581 cctgatgaca ggtttgatgg ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt
     5641 cttaggcgcc ctccttactg ggaaatatga agctatttat agtatcgggg cttggttgat
     5701 tggtgtggcc gtagtcggtc tagttgctgg tggactcaat gttgtcctcg cagcctatat
     5761 tgcccaagga gtttcatccg accttcggga ggatgccttc cgtaaaattc aaaccttttc
     5821 ttatgctgat attgaacaat ttaatgcggg aaatctagtc gttcgaatga caaatgatat
     5881 caaccagatt cagaacgttg tcatgatgac cttccagatt cttttcagac ttcccctctt
     5941 gttcatcggt tcgtttatcc tagcggttca aaccttacct tctctgtggt gggtgattgt
     6001 tctcatggta gtcttgattt ttggtttgac tgctgtcatg atgggaatga tggggcctcg
     6061 ttttgccaag tttcaaaccc ttcttgagcg catcaatgcc attgccaagg aaaatttacg
     6121 tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag caatttgcta agtttacaga
     6181 ggtctcagac gagcttcttg gtcaaaacct ttacattggt tatgcctttt cagtagtgga
     6241 accctttatg atgttggttg gttacggggc ggtcttcctc tctatttggc tggtcgcggg
     6301 aatggttcag tcggatccgt ctgttgttgg ttccatcgct tcttttgtta attacctaag
     6361 ccagattatc tttaccattg ttatggttgg atttttggga aattctgtca gccgtgccat
     6421 gatttccatg cgtcgtattc gagaaattct tgacgcagag ccagctatga ccttcaagga
     6481 tatcccagat gaagagttgg ttggaagcct tagctttgaa aatgtgacct ttacctatcc
     6541 aatggacaat gaaccgatgc tgaaagatgt gagctttact attgaacctg gtcaaatggt
     6601 tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct
     6661 ctttgatcca cagaacgggg ccattaaaat cggtggcaag gatattcgag aagtgagtga
     6721 aggaaccctg cgtaaaacag tttccatcgt tctccaacgt gccattcttt ttagtggaac
     6781 gattgcagat aacttgagac aggggaaggg aaatgctact ctatttgaaa tggagcgcgc
     6841 agccaatatt gcccaggcta gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc
     6901 agttgaagaa cggggaacca atttctctgg tggacaaaaa caaaggatgt cgattgcgcg
     6961 tgggattgtc agcaatccac gtattctgat ttttgacgat tcgacctcag ccttggatgc
     7021 caaatcagag cgcttggtgc aagaagcttt gaataaggac ttgaagggga cgacaaccat
     7081 tattattgct caaaaaatta gctcggttgt ccatgcagac aagatcttgg ttctaaatca
     7141 aggacgattg attggtcaag gcacgcatgc agacttggtt gccaacaatg ccgtttaccg
     7201 tgaaatctat gaaacacaga aatgaaagac aaactataag aaaagtcaat agttttatct
     7261 aaattatttc ttatttcaat ttgatgattt ggcgatgatt ttagagcacg gcaaaaagcc
     7321 cttgaaaaag tccatttttt caaaggtaat cctgtgttga tttcagaaat tacatcactt
     7381 tttgttcgtc aaatggcagc tcttttttag gatataaaac agggttcgga taagtttttt
     7441 tgtaaggtgg atgatggcta cattgtaatg ttttccttat tctaacttag tcttaagata
     7501 ggccttaaaa gcaggtgaaa agcgagggca tgctttggca gcttgtatga gtgcctaccg
     7561 cagatgaggg gaaccccgtt tgatcattct tccagctaaa tcaatctgat ctgactgata
     7621 aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat
     7681 attttgaatc tcggctaaaa tgaccgcccc taaacgattc ccaatcccag taaccgtcgt
     7741 gatgatcgag ttgaactcag ccatcaagtc attgacacat gtttccgcct tgtcaatgag
     7801 cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtttatgcg ttatcaaact
     7861 catgaccaat tgaaacaaaa agctgtggtt agatcctttc ggaaattgtc aagcgattgg
     7921 aggaaatgaa ctaatccaca gcggcttatt ccaagtatac cacttgggct ttggcagtag
     7981 ctaactgcgc taaatataat ataaggagga gtaaaatgaa gacagttcaa tttttttggc
     8041 attattttaa ggtttacaag ttctcatttg tagttgtcat cctgatgatt gttctggcga
     8101 cttttgccca agccctcttt ccagtctttt ctggacaagc ggtgacgcag ctagccaatt
     8161 tagttcaagc ttatcaaaat ggcaatccag aacttgtatg gcaaagccta tcaggaatca
     8221 tggtcaatct tggcctgctg gttttggttc tatttatctc tagtgtaata tacatgtgtc
     8281 tcatgacgcg cgtgattgca gaatcgacca acgagatgcg caaaggcctc tttggtaagc
     8341 ttgctcagtt gacggtttct ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt
     8401 ttaccagtga tttggataat atcctccaag cctttaacga aagcttgatt caggtcatga
     8461 gcaatattgt tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg
     8521 ctctcatcac cattgccagc accccattgg ctttccttat gctgattttc atcgtgaaaa
     8581 tggcacgcaa atacaccaac ctccagcaga aagaggtagg gaagctcaac gcctatatgg
     8641 atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag gatatgatgg
     8701 caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct
     8761 caggaattct tttccctgtc atgaatggga tgagcctgat taatacagcc atcgtcatct
     8821 ttgctggttc ggctgtactt ttgaatgata agtctattga aacaagtaca gccctaggtt
     8881 tgattgttat gtttgcacaa ttttcacagc agtactacca gcctattatc caagttgcag
     8941 cgagttgggg aagccttcag ttggccttta ctggagctga acgaattcag gaaatgtttg
     9001 atgcagagga ggaaatccga cctgaaaagg ctccaacctt cactaagttg caagaaagtg
     9061 ttgaaatcag tcatatcgat ttttcatact tgcctgataa acctattttg aaagatgtca
     9121 gcatttcttc ccctaaaggc cagatgacag cagttgttgg gccgacaggt tcaggaaaaa
     9181 cgactattat gaacctcatc aatcgctttt atgatgttga tgctggtggt atttattttg
     9241 atggtaaaga cattcgtggc tatgacttag atagtcttag aagcaaggtg ggaattgtat
     9301 tgcaagattc ggtcttgttt agcggaacga ttcgagacaa tatccgattt ggtgtgccag
     9361 atgctagtca ggaaatggtt gaggtagcag caaaagcaac ccacattcac gactatatcg
     9421 aaagtttgcc tgataagtac gatactctta ttgatgatga ccagagcatc ttttcaacag
     9481 ggcagaagca attgatttca atcgctcgaa ccctgatgac agatccagaa gttctcattc
     9541 tcgatgaagc aacttcaaac gtagatacgg tgacagaaag caagattcag catgccatgg
     9601 aggtggttgt agcaggtaga actagtttcg tcattgccca ccgcttgaaa accattctca
     9661 atgcagatca gattattgtc cttaaagatg gagaagtcat tgaacgtggt aaccaccatg
     9721 aacttttgaa gctaggtggc ttttattcag aactctatca caatcaattt gttttcgaat
     9781 gagaaagaag ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg tttatcacag
     9841 ccttaaaaaa aacatattag acgaaagtca ttttgagtga tatgatagga ctatcgttag
     9901 cattcgaaag gagaggcatc atggctagaa cggttgtagg agttgctgca aatctatgtc
     9961 ccgtagacgc agaaggcaaa atcattcatt catctgtatc ttgtagattc gcagagatca
    10021 ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg tgatgagtca gttgtacgtg
    10081 attatgtgga aatgattgac aaactcattt tgacaggagg ccaaaatgtt catcctcagt
    10141 tttatggaga gaaaaagacc gtcgagagcg atgattacaa tctggtccgt gacgaatttg
    10201 aattggcact cttgaaggaa gcgcttcgtc agaataaacc aattatggca atctgtcgcg
    10261 gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact
    10321 ggcaaggact acctttcggg acatctcact ctattgagac agtagaagga agcgtggtgg
    10381 ctaagctatt tgggaaagaa agtcaggtca attcagtcca tcgtcaaagc attaaagatt
    10441 tggcacccaa tttccgtgta actgctattg attcaagaga ccaaactatt gaagcgattg
    10501 agtctatcga cgagcaccgc attatcggtt tacagtggca tccagagttt ctggttaatg
    10561 aagaagatgg caatttagaa ttatttgagt atttattgaa tgaactgtaa cgattggaac
    10621 atctggtcgt tctttctttt attttttcaa aatttttaga atgtggtatt ttacgcaaac
    10681 gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta
    10741 agcgttatga tagaaaagaa gaaatattgg aggaagaaca tgtcacatat taaatttgat
    10801 tattcaaaag ttttagacaa atttgttgca ccacatgaag tggaatacat gcaatcacaa
    10861 gtaacagcag cagatgaatt gatccgtaaa ggaactggtg ctggtagcga cttcttggga
    10921 tggttggacc ttcctgaaaa atacgaccgc gaagaatttg accgcatctt gaaagctgct
    10981 gagcaaatca agtcagacag cgatgttttg gttgtgatcg gtattggtgg atcttacctt
    11041 ggtgcaaaag cagcaatcga cttcttgaat caccattttg ctaacttgca aacaaaagaa
    11101 gaacgcaaag ctccacaaat cctttacgca ggaaactcaa tctcatctac ttaccttgct
    11161 gacttggtag agtatgttgc agacaaagac ttctcagtaa acgtaatttc taaatcaggt
    11221 acaacaactg aaccagcgat tgctttccgt gtctttaaag aactcttggt taagaaatac
    11281 ggtcaagaag aagctaacaa acgtatctat gcaacaactg accgccaaaa gggtgctgtt
    11341 aaggttgaag cagacgctaa cggttgggaa acatttgttg ttccagatga tatcggtgga
    11401 cgcttctcag tattgacagc cgttggtttg cttccaatcg cagcatcagg agctgacatc
    11461 aaagctctta tggaaggtgc gaatgcagct cgcaaagact acacttcaga caaaatctct
    11521 gaaaacgaag cttaccaata cgcagctgtt cgtaacatcc tttatcgtaa aggctatgca
    11581 actgagatct tggtaaacta tgagccatca cttcaatact tctcagaatg gtggaaacaa
    11641 ttggctggtg aatcagaagg aaaagaccaa aaaggtatct acccaacttc agccaacttc
    11701 tcaactgact tgcactcact tggtcaattt atccaagaag gaactcgtat catgtttgaa
    11761 acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt ggaagaagac
    11821 cttgacggac ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact
    11881 gacggtgttc ttcttgccca cacagatggt gatgtaccaa acatgtatgt gactcttcca
    11941 gagcaagacg ctttcactct tggttacact atctacttct tcgaattggc aattgccctt
    12001 tcaggttact tgaatgctat caacccattt gaccaaccag gtgttgaagc ttataaacgt
    12061 aacatgtttg cccttcttgg aaaaccagga tttgaagaat tgagcaaaga acttaacgca
    12121 cgtctataat agaagaaaag agtggtttac ccactctttt tactctcttt atccatagaa
    12181 attggactca gtcaagactt gtgatataat atagaaagca aaaaggcaga tgcctagata
    12241 ataggagaaa ctatgtcaaa agatatccgc gtacgttacg caccaagtcc aacaggacta
    12301 ctacacatcg gaaatgctcg tacagcattg tttaattact tgtatgcgcg ccatcatggt
    12361 ggaacatttc tcatccgtat cgaagatact gaccgtaaac gccatgtcga ggatggtgaa
    12421 cgttcacaac ttgaaaacct tcgctggtta ggcatggatt gggatgaaag tccagaatca
    12481 catgagaatt atcgccagtc tgagcgttta gacttgtatc aaaaatacat tgaccaacta
    12541 ttagctgaag gaaaagccta taaatcttac gttacagaag aagagttggc agctgaacgc
    12601 gaacgccaag aagtagctgg cgaaacacca cgctacatca atgaatacct tggtatgagt
    12661 gaagaagaaa aagcagctta catcgcagaa cgtgaagcag cagggatcat cccaactgtt
    12721 cgtttggctg tcaatgagtc aggtatctac aagtggcatg atatggtcaa aggcgatatc
    12781 gaatttgaag gtggcaatat cggtggtgac tgggttatcc aaaagaaaga cggttaccca
    12841 acttacaact ttgccgttgc catcgatgac cacgatatgc aaatctctca tgttatccgt
    12901 ggagatgacc atattgctaa tacaccaaaa cagcttatgg tctatgaatc tcttggttgg
    12961 gaagctccag agttcggtca catgaccttg attatcaact ctgagactgg taagaagtta
    13021 tctaaacgtg atactaatac acttcaattt atcgaagatt accgaaagaa aggttacctt
    13081 ccagaagcag tctttaactt tattgctctt cttggttgga acccaggtgg tgaagatgag
    13141 attttctctc gtgaagaact cattaaactt tttgatgaaa accgcctcag caagtcacca
    13201 gcagcctttg atcagaaaaa actagactgg atgagcaatg attatatcaa gaatgcagac
    13261 cttgaaacca tctttgaaat ggcaaaacca ttcttagagg aagcaggccg tttgactgac
    13321 aaggctgaaa aattagttga gctctataaa ccacaaatga aatcagtaga tgagattatc
    13381 ccattgacag atcttttctt ctcagatttc ccagaattga cagaagcaga gcgcgaagtc
    13441 atgacgggtg aaacagttcc aacagttctt gaagcattca aagcaaaact tgaagcgatg
    13501 acagatgata aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt tcaaaaagaa
    13561 acaggtatta aagggaaaaa tcttttcatg cctattcgta tcgcagtttc aggcgaaatg
    13621 catgggccag aattaccaga tacaattttc ttgcttggac gtgaaaaatc aattcagcat
    13681 atcgaaaaca tgctaaaaga aatctctaaa taaagaggat acaataatgg acatctggga
    13741 aaagatgtac gaagaagcac agaaactata caatccacat gaagtatcag actttgttta
    13801 tgccaatcat gttgtagctg cagtagaagc agaagatgga caaatattta caggattctg
    13861 tatggaggga acctgtggtg ttttccatct ctgcgcagaa cgggcggccc tcttcaatat
    13921 gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag acaaaccacc
    13981 ttatggtgga agttcagcca tgccttgcgg tgcttgtaga gaattccttt tagagcttaa
    14041 tgctgaaaat aaagatgcag aattcatgat ggactataat ataagaaaaa cagttaaagt
    14101 cgcagaacta atcccttatt ggtggggaga agaacgtgct tctaagttta atgagcgata
    14161 gaagagtcag tataattttg gctcttttta ctataagttg aaaaaata
//
LOCUS       DAVBNN010000051        13168 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBNN010000051 DAVBNN010000000
VERSION     DAVBNN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.051"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            268..882
                     /locus_tag="VQ847_001632"
     CDS             268..882
                     /locus_tag="VQ847_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3050938.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            986..1816
                     /locus_tag="VQ847_001633"
     CDS             986..1816
                     /locus_tag="VQ847_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3050939.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1970..2824
                     /locus_tag="VQ847_001634"
     CDS             1970..2824
                     /locus_tag="VQ847_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3050940.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2924..4297
                     /locus_tag="VQ847_001635"
     CDS             2924..4297
                     /locus_tag="VQ847_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3050941.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4290..5351
                     /locus_tag="VQ847_001636"
     CDS             4290..5351
                     /locus_tag="VQ847_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3050942.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5353..6045
                     /locus_tag="VQ847_001637"
     CDS             5353..6045
                     /locus_tag="VQ847_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050943.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6075..6644)
                     /locus_tag="VQ847_001638"
     CDS             complement(6075..6644)
                     /locus_tag="VQ847_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3050944.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6779..7393
                     /locus_tag="VQ847_001639"
     CDS             6779..7393
                     /locus_tag="VQ847_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3050945.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7395..9041
                     /locus_tag="VQ847_001640"
     CDS             7395..9041
                     /locus_tag="VQ847_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3050946.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9053..10339
                     /locus_tag="VQ847_001641"
     CDS             9053..10339
                     /locus_tag="VQ847_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3050947.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10391..10924
                     /locus_tag="VQ847_001642"
     CDS             10391..10924
                     /locus_tag="VQ847_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3050948.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11002..11472
                     /gene="nrdI"
                     /locus_tag="VQ847_001643"
     CDS             11002..11472
                     /gene="nrdI"
                     /locus_tag="VQ847_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3050949.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11765..13027)
                     /locus_tag="VQ847_001644"
     CDS             complement(11765..13027)
                     /locus_tag="VQ847_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3050950.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3899 a         2451 c         3007 g         3811 t
ORIGIN      
        1 ttcaatctgc tatataatag tccatgctat ggctggattc ttttcagtct acttatactc
       61 ttcgaaactc tcttcaaacc acgtcagctt caccttgccg tagtacggtt actgacttcg
      121 tcagttctat ccacaacctc aaaacggtgt tttgagcaac ctgcggctag tttcctagtt
      181 tgctctttga ttttcattga gtattattaa gacaatatga ggagaaagat gaaagaaaaa
      241 ggattttagg agggggcgca ggcagccatg ccaacggctc ttggctatgt cagtatcggc
      301 ctggcctgtg ggactatcgg tgcgccctat gtgacacctg ttgagatggg cttgatgagt
      361 ctctttgttt atgctgggag tgcccagttt gccatgttgg cactgattgt ggttcaagct
      421 cctgtggcag ctattgctat gacggttttt ctaatcaact tgcgtctctt tttgttgagt
      481 ttacacgcat cgacttattt ccgtcatacc agtctttggt acaatatcgg tatgtctagt
      541 atcttgacag atgagaccta tggcgttttg atgggtgaat tggcccatac agacaaggta
      601 aatcctatgt ggatgcacgg aaacaatctt aacagctatg tggcttggtt tgtggggaca
      661 gtagtcggaa cggctctggg tggcctgcta ccaaatccag aaatctttgc cttgattctt
      721 tcaagcgtag tgacaggtaa ggttgggagc cttcctcaaa ttaaatggct agacttctta
      781 gccgtctttc caacagcttg ggtagccttt cgctaccgca atctagtcgg aacagttctc
      841 tttggagtgg tcttgattgc catcttgcgt ttggtctttt aaattaccca taaaaaaaac
      901 ttatcacaga gatagatatc atataatggc gtaaatgctc tttttctgtt aagattataa
      961 ggtattctat tttggaggaa atgacatgaa aaaaatcgtt aaatactcat ctcttgctgc
     1021 cctaggactt gttgctgcag gtgtgcttgc ggcttgctca gggggtgcta agaaagaagg
     1081 agaagcagct agcaagaaag aaatcatcgt tgcaaccaat ggatcaccaa ggccatttat
     1141 ctatgaagaa aatggcgaat tgactggtta cgagattgaa gtcgttcgcg ctatctttaa
     1201 agattctgac aaatatgatg tcaagtttga aaagacagaa tggtcaggtg tctttgctgg
     1261 tcttgacgct gaccgttaca atatggctgt caacaatctt agctacacta aagaacgtgc
     1321 ggagaaatac ctctatgccg caccaattgc ccaaaatcct aatgtccttg tcgtgaagaa
     1381 agatgactct agtatcaagt ctctcgatga tatcggtgga aaatcgacgg aagtcgttca
     1441 agccactaca tcagctaagc agttagaagc atacaatgct gaacacacgg acaacccaac
     1501 tatccttaac tatactaagg cagacttcca acaaatcatg gtacgtttga gcgatggaca
     1561 atttgactat aagatttttg ataaaatcgg tgttgaaaca gtgatcaaga accaaggttt
     1621 ggacaacttg aaagttatcg aacttccaag cgaccaacaa ccgtacgttt acccacttct
     1681 tgctcaaggt caagatgagt tgaaatcatt tgtagacaaa cgcatcaaag aactttataa
     1741 agatggaact cttgaaaaat tgtctaaaca attcttcgga gacacttatc taccggcaga
     1801 agctgatatt aaataatttc ttgaaatcat ccattctgag taaggtgggt ggtttctcag
     1861 tttttaggga tatagtttta aactatatat ctgactatct aataacaatt tgtgaaatca
     1921 aacaaattgt gagatactag tacggtatta tttttaagga gaaagaatca tgaaaatcaa
     1981 aaaatggctt ggtctagcag cccttgctac agtcgcaggt ttggctcttg cagcttgcgg
     2041 aaactcagaa aagaaagcag acaatgcaac aactatcaaa atcgcaactg ttaaccgtag
     2101 cggttctgaa gaaaaacgtt gggacaaaat ccaagaattg gttaaaaaag acggaattac
     2161 cttggaattt acagagttca cagactattc acaaccaaac aaagcaactg ctgatggcga
     2221 agtagatttg aacgctttcc aacactataa cttcttgaat aactggaaca aagaaaacgg
     2281 aaaagacctt gtagcgattg gagatactta catctctcca atccgccttt actcaggttt
     2341 gaatggaagt gccaacaagt acactaaagt agaagacatc ccagcaaacg gagaaatcgc
     2401 tgtaccgaat gacgctacaa acgaaagccg tgcgctttac ttgcttcaat cagctggctt
     2461 gattaaattg gatgtttctg gaactgctct tgcaacagtt gccaacatca aagaaaatcc
     2521 aaagaacttg aaaatcactg aattggacgc tagccaaaca gctcgttcat tgtcatcagt
     2581 tgacgctgcc gttgtaaaca ataccttcgt tacagaagca aaattggact acaagaaagc
     2641 acttttcaaa gaacaagctg atgaaaactc aaaacaatgg tacaacatca ttgttgcgaa
     2701 aaaagattgg gaaacatcac ctaaggctga tgctatcaag aaagtaatcg cagcttacca
     2761 cacagatgac gtgaaaaaag ttatcgaaga atcatcagat ggtttggatc aaccagtttg
     2821 gtaataagaa acagggaggt gggagagaaa attccacctc ttgcttttgt atagagtata
     2881 gattgtaaag aagactattc gttcatagaa aggtagagag aatatgtttt ttcctagcga
     2941 acaagaacag attgaaaaat ttgaaaagga tcatgtagcc cagcattatt ttgaggtttt
     3001 gcgtaccttg atttctaaga aatcagtctt tgcccagcag gttggactca aggaagtcgc
     3061 aaactatctg ggtgagattt tcaagcgtgt tggagctgaa gtggagattg atgagagcta
     3121 tacagcgccc tttgtcatgg cacatttcaa gagttcgcgt ccagatgcca agaccttgat
     3181 tttctataac cactatgaca ctgtgccagc ggatggggat caggtctgga cagaggatcc
     3241 ttttacgctt tcggtccgca atggcttcat gtatgggcgt ggggttgatg acgacaaggg
     3301 tcatatcaca gctcgcttga gtgctttgag aaaatatatg cagcaccatg atgatttacc
     3361 tgtcaatatc agctttatca tggagggagc ggaggaatcg gcttcaacag acctagataa
     3421 gtatttggaa aagcatgcag acaaactctg tggggcggat ttgttggtct gggaacaagg
     3481 gaccaaaaat gccttggaac agctggaaat ttctggtggc aataagggaa ttgtgacctt
     3541 tgatgccaag gtaaaaagcg ctgatgtgga tatccactcg agttatggtg gtgttgtgga
     3601 atcagctcct tggtatctcc tccaagcctt acagtctctt cgtgctgcgg atggccgtat
     3661 cttggttgaa ggcttgtacg aagaagtaca agagcccaat gaacgagaaa tggccttgct
     3721 agaaacttat ggtcaacgaa acccagagga agttagtcgg atttatggat tggagttgcc
     3781 tctcttacag gaggagcgga tggcctttct aaaacgtttc tttttcgagc cagcgcttaa
     3841 tatcgaagga atccagtctg gttatcaagg tcagggtgtt aagactattt tacctgcaga
     3901 agccagtgca aagctagagg ttcgtctggt tccgggccta gaaccgcatg atgttctgga
     3961 aaaaattcgg aaacaactag acaaaaatgg ctttgataag gtagaattat actatacctt
     4021 gggagagatg agctatcgaa gcgatatgag cgcaccagcc attctcaatg tgatcgagtt
     4081 ggccaagaaa ttctatccac agggtgtttc agtcttgccg acgacagcgg ggacaggacc
     4141 tatgcatacg gtctttgatg ccctagaggt accaatggtt gcattcggtc taggaaatgc
     4201 caatagccga gaccacggtg gagatgaaaa tgtgcgaatc gctgattatt acacccatat
     4261 cgaattagta gaggagctga ttagaagcta tgagtagaga tattatcaag ttagatcaga
     4321 tcgatgtgac ttttcaccaa aagaagagaa ccattacagc ggttaaggat gtgaccattc
     4381 acatccaaga aggggatatc tacggaatcg ttggatattc tggagcagga aaatcaaccc
     4441 ttgtacgggt gattaacctc ttgcaaaaac catctgcagg gaaaattacc attgacgacg
     4501 atgtgatttt tgatggtaag gtcaccttga cggcagagca gttgcgtcgt aaacgtcaag
     4561 atatcgggat gattttccag cattttaacc tgatgagcca aaagacagca gaggagaatg
     4621 tagcctttgc ccttaaacac tctggactca gcaaggaaga aaagaaggct aaagtagcta
     4681 agttgttgga cttggttggt ttggcagatc gtgctgaaaa ctacccttca caattatctg
     4741 gagggcaaaa acagcgtgtg gcaattgcgc gtgccttggc caatgatcca aaaatcttga
     4801 tttcagacga gtcaacttct gcccttgacc ctaagacaac caagcagatt ttggccttgt
     4861 tgcaagattt gaaccaaaaa ttaggcttga ctgttgtctt gattacgcat gaaatgcaga
     4921 ttgtcaaaga cattgccaac cgtgttgcag ttatgcagga tgggcatttg attgaagagg
     4981 gtagtgtgct tgaaatcttc tcaaacccta aacaaccttt gactcaagac tttatctcaa
     5041 cagctacagg tattgacgaa gccatggtca aaatcgagaa gcaagaaatc gtggaacact
     5101 tgtctgaaaa cagtctcttg gtgcaactca agtacgctgg agcttcaaca gacgagccac
     5161 ttttgaatga attgtacaag cattaccaag taatggctaa tattctctat gggaatatcg
     5221 aaattctcga tggtactcct gttggagaat tggtggtggt tttgtcaggt gaaaaagcag
     5281 cgttggcagg tgcccaagaa gccattcgtc aagcaggtgt acaactaaaa gtattgaagg
     5341 gagtacagta agatggaatc attgattcaa acctatttac caaatgtcta taagatgggt
     5401 tgggctggtc aggcaggctg gggaacggct atctacttaa ctctttatat gacagttctt
     5461 tccttcatta tcggaggctt cttggggcta gtggcaggtc tctttctcgt cttgacagcg
     5521 ccaggtggtg tcttggagaa taaagtcgta ttctggattt tagacaaaat tacctcaatt
     5581 tttcgtgcgg ttccctttat catcctcttg gcaatcttgt caccactttc tcacttgatt
     5641 gttaaaacaa gtatcgggcc aaatgcagcc cttgtcccac tttcttttgc agtctttgcc
     5701 ttctttgccc gtcaggtgca ggttgtcttg gctgaattgg atggcggtgt cattgaggcg
     5761 gctcaagcga gcggagcgac tttctgggac atcgtgggtg tttacctatc agaaggtctt
     5821 ccagatttga tccgtgtgac gactgtgacc ttgatttccc ttgttgggga aacagctatg
     5881 gccggtgcgg ttggagctgg tggtatcggt aacgtagcca tcgcttatgg atttaaccgc
     5941 tacaatcacg atgtgaccat cttggcaacc attattatca ttttgattat ctttgcaatc
     6001 caattcttgg gagatttctt gactaagaaa ttgagccata aataaaaaag agccgcgtgg
     6061 ctctttttaa ctgatcagat tttctgtgca aattttttac tcaaggcttg tccaatcaaa
     6121 gcacccacta gggctccgat gacaatactt gcgataaata gaaggacagt tccagggttt
     6181 ggagcgacca tgatacggtc gatatattct tgggattttc ctcttgccag aagagtagcc
     6241 atataggctt tgggcgcaat ccacataagc aagattggtc ctgttgtact aaaggcgaaa
     6301 ataatgaaag aaaggaagtt ctttgttttg tccttgtatt ttcctaaatg agctacttca
     6361 tctgctagga ggccacagat aattccagga aggaaggaac cagcaccgtg tttagttccc
     6421 aagaaaaaga aggcaatgac aaggccgata gtggtaatgg ctccaaagcg cggaactttt
     6481 gcgactagga tcatatagac gctaccgccg acaagggcag taaaggcagg cgcataaaac
     6541 atgtttccag tttggtcaaa gagattgccc aaaaggacac caatccccat gcagaggaag
     6601 taaagaactg caaaaagcag tgtagttaag atagatttct tcatgaattg tctcctgata
     6661 attttttcac aattctcatt ttaccatggt ttggtgggat tgtaaatgga tactagaagt
     6721 ttttgaaaac gcttgaaata tgatataatg gtttcatagt tatttttagg ggaatatcat
     6781 gggtagattt ttagactttg tctttaatcg tttcttttta gggatgattg cgacagcctt
     6841 cttttggcta ttaactttag caggagggat tatccttggt ctagcgccgg ctagtgccac
     6901 cttgatgagc ttatatgcag aacatggtta tagctttcgg gaatacagtt tgaaggaggc
     6961 ttggtctctt tacaagcaaa attttgtctc aagcaacctg attttctata gctttttagg
     7021 tgtgggtcta gttttgacct atggtttgta tctcttggtg caattgcctc atcagaccat
     7081 tgttcatttg attgcgaccc ttttgaatgt cttagtagtt gccctgatct ttttggctta
     7141 tacagtatct ttaaaattac aagtttattt tgccttgtcc tatcgaaata gtctcaaatt
     7201 atccttgatt ggcatcttta tgagtctagc agctgtggcc aaggttctcc ttgggactgt
     7261 gctacttgta gcaattggtt actatatgcc tgccctgcta ttttttgtag gaattgggat
     7321 gtggcatttc tttatcagtg atatgttgga acctgtctat gaaatcatcc atgaaaaatt
     7381 ggcgacaaaa tagaatgaag cagttttggc tacatacgct tctaagaacc tatagttcag
     7441 tgatgatcat tatcattgcg agttttgcaa tcttactctc ttacgctgac tgggattcac
     7501 gtgaaaagga agcccagaga gtagcccagc gtgtaactgc tagaacagtg agtgaaattg
     7561 aatattacca tagagagtca acccagatag ctcaggcttt agttgaaaat caagctcgta
     7621 ttgagggaat ctataaatac tttagcctta gcatgccaga ctatttttac tggcaattag
     7681 agcggaaagc ttcgccttat atatcagtct ctctgtatga aaatgttgat gacctctatg
     7741 ttcgaaatga ttttgtaact ggagtggcca ttgcttttca agattacaag gaagtctatg
     7801 tttctactaa agacaaacgt agtggagaaa aaatcagggc tgaggatttc aaaccagcag
     7861 gaaatagttt tgccattccg gtgtcagatc cagtgtcaga tcaagattta ggagtgattt
     7921 acatctcctt ggatcctgct gttttatacc atgccattga taatactaga ggtaatactc
     7981 cgatggcagt aacagtgacc tcaccttttg atacggagat ttttcatatt ggtgagacag
     8041 ttgataagga gagtgaaaat tggctagttg gcttaacttc tcatggatat caggttcagg
     8101 tggcagttcc taaaaacttt gttttacaag gaacagtgac tagctctgct ttgattgtgg
     8161 gtttgagcct tctctttatt gtcattcttt atctgacttt gaggcagact tttgctaatt
     8221 accaaaagca ggtagtggat ttagtagaat ccattcaagt cattgctcaa ggcgaagagg
     8281 gtcgtcggat tgacatttcc gagaaagatc aggaattact cctaatcgcg gagacgacca
     8341 atgatatgtt ggatcgattg gaaaagaata tccatgatat ttaccagtta gagcttagtc
     8401 aaaaagatgc taatatgcga gccttgcagg cgcaaatcaa tcctcatttt atgtataata
     8461 cgctggagtt cttgcgcatg tatgcagtta tgcagagtca agatgagttg gcagatatca
     8521 tttatgaatt cagtagtctc ttgcgtaaca atatttccga cgaaagagag accctcctca
     8581 aacaggaatt agaattttgc cgtaaataca gctatctctg catggttcgc tatcccaagt
     8641 ccattgccta tggtttcaag atagatccag agttagagaa tatgaagatt cctaagttca
     8701 ccttgcaacc gctggtagaa aattatttcg cgcatggtgt tgaccacagg cggacagata
     8761 atgtgattag catcaaggct cttaaacagg atggttttgt ggaaattttg gtggtcgata
     8821 atggtagagg aatgtcggct gaaaagttgg caaatatccg agaaaaatta agtcagagaa
     8881 attttgaaca ccaagccagc tacagtgatc aaaggcagtc tatcgggatt gtcaatgtac
     8941 acgagcgttt tgtgctctat tttggagacc gctatgccat tactatagag tctgcagagc
     9001 aagccggtgt tcagtatcgt attacaattc aagatgagta gaaagggaga aaatgtataa
     9061 agtattatta gtagatgatg agtacatggt gacagaaggt ctgaagcgtt tgattccctt
     9121 tgataagtgg gatatggagg tcgtcgcaac agccagtcat gccgatgaag ctctagaata
     9181 tgttcaggaa aatcctgtcg atgtcatcat ttccgatgtc aatatgccag acaaaacagg
     9241 gcttgatatg attcgggaga tgaaagagat cttaccagat gctgcctata tcctgctctc
     9301 aggttatcag gagtttgatt atgtaaaaag agcaatgaac cttagtgtgg tggactattt
     9361 ggtcaaacct gttgataagg tagagctggg aaatctgctg gagaagattg caggtcagct
     9421 cggcgagaga gggaagaaaa gtcagactct tagtcaagaa ttagacgagg ctggatttgt
     9481 tagttattta ggggataagg agaattggtg gataggtcta tccaaggaaa aacaaggttc
     9541 cttcaccatt ccctactatg tcttgggtca agcctggcag attttcattt ctgaccaacc
     9601 cctagatggt ttagtcgtta caccttttga agctccttat caagaacatt ttgaacgctg
     9661 gaagctgaat gctgagaaaa ccctctttta cggttctgta aatctgcagc agtctgagag
     9721 tctctttgcc tattacgaac cgatttatag ggttatcatt cagggaaatc tcaatcaaat
     9781 cgtagaagag ttaaatctct tggagaaggt agttcttgaa aatacgccgc gaattccgat
     9841 tactaaacag ctttttatcc agtttgtcat ggatgtcttc catttatttg aacatctcaa
     9901 agctgatgat atgacggaca ttgtcaaaac cattcatgct attcaatcct tcgatgaatt
     9961 ggtttcttat atcaaggaaa ctctgatcag ctttttcggt caataccgta tgaatgaaaa
    10021 tgtggtcagt gtgctggaag tcattggtcg tgattaccaa aaagagcttt ccctcaagga
    10081 tatcagtaag gccctcttta tcaatcctgt ctatctaggg cagttgatta agcgtgaaac
    10141 cgattcgacc tttgcagagt tactaaacaa acaacgtatt aaggctgccc agcagctctt
    10201 gctttcaacc agtgacagta tcgaagatat ttgttatgct gttggttaca gtaaccttgg
    10261 atatttctat aaagttttcc gaaaattgtg cggaaaatcg ccaaaagcct accgaaaaca
    10321 ggtagaaact atactataag atttgtattc ctttacaaaa tgtgctataa tattatcagg
    10381 aggttctatc atgaaaaaga aaccaattta tctatgggtc ttgctaatct tgtctgccct
    10441 tatttcagtt ccgtctctgt ttggaattgt gagtcccttg cctagtaaag aagcccttcg
    10501 tgttgctcag aaacaagttg caggggtcaa tgctcagcaa ttagaagacc agcttaatta
    10561 tacctataga gtagcagaag catctcattc tatttttaat gttgctttga ttgtgctatc
    10621 tactatttta gtggtcgtag cgattgtctt ccttgttcgt aaaaatttgc aatatgcaaa
    10681 ctatacttac gttggctatg ttttgttagc tattattggt tcgatttatg gctatgttgg
    10741 tttacaagac gctgtgcagt tggttcaaga tgagagcatg cgtttgacag tgagtattgg
    10801 ttcaaaagct gttagcattt tctatatcgt catcaatgtt ctcttcctag cccttgtctt
    10861 ctataagatg tggcgacaac agaaagcctt ggcagaagaa gaggaaacag aagagcttgc
    10921 ctaagtattg acaaaaaaga actatcaaga tacaatcttg gtagttattt tttgattata
    10981 gataaaatca tggaggtaca tatgaagaca atttctttag tttatattag tttgagtggc
    11041 aacactgaaa gttttgtgac gcgcttgaaa gactatctct tgtcccagta caaagggatt
    11101 gaggttcaaa agattcatat caaggatttg gtcaaggaag gcaaaaattt ctatgaaatg
    11161 gaccatctct atgtcgcttt tttgccgacc tatctcgaag gtgggaatgg cgtggataac
    11221 ggagatgttg agattttgac aacaccggtg ggagatttta ttgcctatgg taacaatgct
    11281 agtaagtgtt ttggtgtggt tgggtcagga aatcgtaact ttaataacca atactgccta
    11341 acagccaagc aatacagtca acgctttggc ttccctgtat tggctgactt tgaaatgcga
    11401 ggcatgctgg aagatatcaa acatgtcgca gctattatcg cagatttgta tgagttggaa
    11461 aaggagaatt aatactcaat gaaaatcaaa gagcaaacta ggaagctagt cgcaggttgc
    11521 tcaaagcaca gctttgaggt tgcagataga gctgacgtgg tttgaagaga ttctcgaata
    11581 gtataaagtt cttataagag gtggttgaag ttgttcaact gttttttgag tataaacagt
    11641 ctttaagaac gtaaaaaagc ataagttcag gtcttcaaaa ccttgttctt atgcttttta
    11701 tcatagaaat atttgctgaa ttttctcttg aaatgaaacc ttatcttcat ctcgcgcttg
    11761 tcccttaccc tgcttttccg attgcgagtg cgtagataaa gaagatggcg aagccaaaga
    11821 ggaaaatcaa tcccgcaatg gcaaggtgtt tgagccaaga aggaagattt ttgttttcac
    11881 gcgttaccaa ggcgtaattc aaaagagcaa agaaaggtgt tgtcaggaaa gatccaatca
    11941 tggcaaagcg gagcatggtt gaaacctgac cagcgaagaa cttgataatg acgataccga
    12001 tgatagcagt gatggtcatc cagatgttca aagatttacg attgtcctct ttttgactga
    12061 ttagcagtcg gagagattcc tgattaacgc gagaatagcc atcgataaca gttataactg
    12121 ttccaaagat acagaggaag gcaataaagg taatcaagta acgggaccat tcgccaagaa
    12181 cagaggcata catgcccacg aattgagaga tgtatttggc tgaagcagct tcaaccgcct
    12241 gccctgtagg atactgaatc agtgctccca gtgccacaaa gaagacggct aggatagctg
    12301 ttccaatata accagtgtta aagtcaaaca gagcgtcttc tgtgttaaag ttgacggtct
    12361 ttctcttttc agctgaccaa agtgaattga tagctgaaat ttcaatagga gccggcatcc
    12421 atcctaggag ggagacgatg aagggcagag ctgccatttg ccaaggtgtc ttctcgacaa
    12481 aatcagaact gtattctgga tgcttgaccg ctgctatgat aactgccaga acagtcgcaa
    12541 tggttaaggc agacataatc catttgacca tgccgtctaa aagtttgtag cctccaaaga
    12601 gtagcatagc ccaaatgatt gcaacgagaa tgagggacca ctgagtaatg ctaagtccaa
    12661 tcattgggaa ggcactggcg atgatagctg agcacagaat ggcaacacca gccgtgttga
    12721 ccatagccga aaagacattg aggataaaga aaatccagag atagagtttt cctttttcgg
    12781 cataaccttc aaccaaagtc tttccagtat cagctgtgta ttcagcacca aaacggaaaa
    12841 atggatattt aaagacattg gctaagatga ctaagagaag tagagaccaa ccgtaagaac
    12901 cgccagcttg agttgaggat acaatgtggg aacctccaac agcggcagtt gccattagga
    12961 ttccaggtcc cattgctttt agcttgcttg cccaggttga ttgatttaag gaaatagctt
    13021 gcgacatgat aaatactcct ttttgaattt tcagaataat ctgtatatgt aatctatatt
    13081 ctacaaaaaa ttttggaaaa atgcaagaat attttgaaaa aagatagaaa atttacaaag
    13141 aaaatctgaa ataactgtta tgatatag
//
LOCUS       DAVBNN010000052        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBNN010000052 DAVBNN010000000
VERSION     DAVBNN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.052"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ847_001645"
     CDS             <1..367
                     /locus_tag="VQ847_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3050951.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ847_001646"
     CDS             complement(442..972)
                     /locus_tag="VQ847_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3050952.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ847_001647"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ847_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ847_001648"
     CDS             1984..2661
                     /locus_tag="VQ847_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3050953.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ847_001649"
     CDS             2648..3445
                     /locus_tag="VQ847_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3050954.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ847_001650"
     CDS             3462..4565
                     /locus_tag="VQ847_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3050955.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ847_001651"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ847_001651"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3050956.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ847_001652"
     CDS             5887..6840
                     /locus_tag="VQ847_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3050957.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ847_001653"
     CDS             complement(6902..7108)
                     /locus_tag="VQ847_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3050958.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ847_001654"
     CDS             7160..7636
                     /locus_tag="VQ847_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3050959.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ847_001655"
     CDS             7645..8316
                     /locus_tag="VQ847_001655"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3050960.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ847_001656"
     CDS             8447..8785
                     /locus_tag="VQ847_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3050961.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ847_001657"
     CDS             8788..9417
                     /locus_tag="VQ847_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3050962.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ847_001658"
     CDS             9657..10808
                     /locus_tag="VQ847_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3050963.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ847_001659"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ847_001659"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3050964.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ847_001660"
     CDS             11865..12638
                     /locus_tag="VQ847_001660"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3050965.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ847_001661"
     CDS             12616..13077
                     /locus_tag="VQ847_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3050966.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3762 a         2466 c         2904 g         4027 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttgcagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBNN010000053        12973 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBNN010000053 DAVBNN010000000
VERSION     DAVBNN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.053"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ847_001662"
     CDS             87..3437
                     /locus_tag="VQ847_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3050967.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3681..3782
                     /locus_tag="VQ847_001663"
                     /pseudo
     CDS             3681..3782
                     /locus_tag="VQ847_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4023..4493)
                     /locus_tag="VQ847_001664"
     CDS             complement(4023..4493)
                     /locus_tag="VQ847_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3050968.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4510..6783)
                     /locus_tag="VQ847_001665"
     CDS             complement(4510..6783)
                     /locus_tag="VQ847_001665"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3050969.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7129..10230
                     /locus_tag="VQ847_001666"
     CDS             7129..10230
                     /locus_tag="VQ847_001666"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3050970.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ847_001667"
     CDS             10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ847_001667"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3050971.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11379..12884
                     /gene="pyk"
                     /locus_tag="VQ847_001668"
     CDS             11379..12884
                     /gene="pyk"
                     /locus_tag="VQ847_001668"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3050972.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4021 a         2204 c         2851 g         3897 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
     3781 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     3841 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     3901 cttcctagga taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt
     3961 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     4021 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4081 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4141 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4201 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4261 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4321 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4381 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4441 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4501 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4561 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4621 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc
     4681 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4741 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4801 gtgatagcga ccgttatcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4861 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4921 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4981 aatagtaatc tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     5041 actatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5101 aagtgagaag gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5161 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5221 taatttcttg gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5281 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc
     5341 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5401 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5461 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5521 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5581 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5641 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5701 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac
     5761 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5821 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5881 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5941 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     6001 ctcagcctct gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt
     6061 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6121 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6181 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6241 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6301 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6361 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6421 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6481 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6541 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6601 atcagctgct aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6661 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6721 ttttagctca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6781 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6841 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata
     6901 tagagaacag agtaacaata agaataatag atagggtata aaagttctag gagatttata
     6961 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
     7021 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     7081 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     7141 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     7201 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     7261 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     7321 gaaatgacag tgtttgtaga tgaacaggaa gtgaatttgc gctttttatc tctatctagt
     7381 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     7441 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     7501 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     7561 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     7621 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     7681 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagtgt
     7741 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     7801 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     7861 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     7921 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     7981 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     8041 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     8101 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     8161 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     8221 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     8281 ttgaaacgct ttggtgtgcc agagtatgaa ttatctgcaa ttactaagaa aatcagtttt
     8341 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     8401 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     8461 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     8521 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     8581 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     8641 gagttgcttg ctgaaacaga aggtattcac cttaaaattg aagaaataga tttggaagac
     8701 aaagaaacgt tagatttatt tgcctctgga aatacaaaag gtatctttca atttgagcaa
     8761 cctggtgcca ttcgcttgct caaacgtgtt caaccagtct gttttgaaga tgtcgtagca
     8821 actacttctc taaatcgacc aggtgcaagt gactacatca ataattttgt ggcaaggaag
     8881 catgggcagg aagaagtgac tgttctagat tcagctctgg aggatatttt ggctccaact
     8941 tatggcatta tgctctatca ggagcaggtt atgcaggttg ctcagcgatt tgctggattt
     9001 agtcttggga aggccgatat tttgcgtcga gctatgggta aaaaggatgc ctctgctatg
     9061 catgagatga gggcttcctt tattcaaggc tccatagaag caggccatac tgcggaaaaa
     9121 gcagagcagg tttttgatgt tatggagaag tttgcaggtt atggatttaa tagatctcat
     9181 gcctacgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     9241 attttttatc aggtcatgtt aaattattcc aacagtgatt acttaataga tgcacttgaa
     9301 gcaggttttg aagtagcctc tctatccatc aatactattc cctatcacga taaaattgcc
     9361 aacaagtcta tctatatagg tttgaaatcg attaaggggc tcagcaagga cttggcgctt
     9421 tggattattg aacatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     9481 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     9541 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     9601 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     9661 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     9721 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     9781 agctatgcta ttattttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     9841 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt cactctcttt
     9901 tcagacttat atcgtcaggt tggacaggaa ataaaagagg gagccttcta ctatgtaaaa
     9961 ggaaaaatac aatcacgtga tggccgtttg caaatgattg cacaagaaat aagagaagca
    10021 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
    10081 attttagaac aatttaaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
    10141 accatcgttt ctccccatca ttttgtagct aaatccaatg aattagagga gaaattgaat
    10201 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
    10261 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaacca atatgaaacg
    10321 tattgctgtt ttgactagtg gcggagacgc acctggtatg aacgctgcta tccgtgcagt
    10381 tgttcgtcaa gcaatttcag aaggaatgga agtgtttggt atctatgacg gatatgctgg
    10441 tatggttgcc ggtgaaattc atcccctaga tgcagcttca gtaggagaca tcatttctcg
    10501 tggtggtact tttcttcact cagctcgtta cccagagttc gctcaacttg aagggcaact
    10561 taaagggatt gagcaattga aaaaacacgg aattgaaggt gtagttgtta tcggtggtga
    10621 cggatcttac cacggcgcta tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc
    10681 aggtacaatc gataacgata tcgttggtac tgactttaca atcggttttg acacagcggt
    10741 tactactgcc atggacgcta tcgataagat tcgtgataca tcatcaagtc accgtcgtac
    10801 ttttgtaatc gaagttatgg gacgtaacgc tggtgatatc gctctttggg ctggtattgc
    10861 aactggtgct gatgaaatca tcatccctga agcaggcttc aagatggaag atatcgtagc
    10921 aagcatcaaa gctggttatg aatgtggtaa aaaacacaat atcatcgtct tagctgaagg
    10981 tgtgatgtca gcggctgaat ttggtcaaaa acttaaagaa gctggagata caagcgacct
    11041 tcgtgtaaca gaacttggac atattcaacg tggtggttct ccaactgcgc gtgaccgtgt
    11101 tttagcgtca cgtatgggtg cacatgctgt taaacttctt aaagaaggta tcggtggtgt
    11161 tgcggttggt attcgtaacg aaaaaatggt tgaaaatcca attcttggta ctgcagaaga
    11221 aggggcattg tttagcctta ctgcagaagg taagattgtg gttaacaacc cgcacaaagc
    11281 cgatattgag ctatctagct tgaataagag cttgtcataa tttacaattt agttaataag
    11341 accaaaaagg tcatatatat aaaggagtca caaaaatcat gaacaaacgt gtaaaaatcg
    11401 ttgcaacttt gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt gaggacggat
    11461 actggggtga aaaacttgat gttgaagctt cagctaaaaa cattgctaaa ttgattgaag
    11521 ctggtgctaa cacattccga ttcaacttct cacacggcga ccaccaagaa caaggtgagc
    11581 gtatggcaac tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg
    11641 atacaaaagg acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa gaatattcat
    11701 acaaaactgg tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag
    11761 tgattgcgtt gaacgttgct ggtgctcttg atatctatga tgatgttgaa gttggtcgtc
    11821 aagttttggt tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc
    11881 gtgaatttga agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca
    11941 tccctaacac taaaattcct ttcccagctc ttgctgaacg cgataacgac gatatccgtt
    12001 tcggtcttga acaaggtatc aacttcatcg caatttcatt cgtacgtact gcaaaagatg
    12061 tgaacgaagt tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa ttgttcgcta
    12121 aaatcgaaaa ccaacaaggt atcgataact tagacgaaat catcgaagca gctgatggta
    12181 ttatgattgc tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc
    12241 aaaaaatgat tatcaagaaa gtcaatgctg caggtaaagt tgttatcact gcaacaaaca
    12301 tgcttgaaac aatgactgaa aaaccacgtg caactcgttc agaagtatca gacgtattca
    12361 acgctgttat cgacggaact gacgctacaa tgctgtcagg cgagtctgca aacggtaaat
    12421 acccactcga gtcagtaact acaatggcta caatcgacaa gaacgctcaa gctcttctta
    12481 atgaatacgg acgtcttgat tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg
    12541 cttctgctgt taaagatgct actaactcaa tggatatcaa attggttgta actcttacta
    12601 agacaggtca tactgcacgt ttgatttcta aataccgtcc aaatgctgac atcttagcat
    12661 tgacatttga cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt
    12721 tgacagatgc tccatcttca actgacgata tgttcgaaat cgctgaacgt aaagcggtag
    12781 aagcaggtct cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag
    12841 aagctgttcg cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc
    12901 tatcatatcc agctttctag cctgtatgat gggctctttt tttgtccagg gggcaaaact
    12961 ttcataatgg att
//
LOCUS       DAVBNN010000054        12762 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBNN010000054 DAVBNN010000000
VERSION     DAVBNN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.054"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..172
                     /locus_tag="VQ847_001669"
     CDS             <1..172
                     /locus_tag="VQ847_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3050973.1"
                     /translation="DKAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMN
                     FIAGIINHELGF"
     gene            363..2654
                     /gene="pcrA"
                     /locus_tag="VQ847_001670"
     CDS             363..2654
                     /gene="pcrA"
                     /locus_tag="VQ847_001670"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3050974.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2697..3377
                     /gene="radC"
                     /locus_tag="VQ847_001671"
     CDS             2697..3377
                     /gene="radC"
                     /locus_tag="VQ847_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3050975.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3374..4063)
                     /locus_tag="VQ847_001672"
     CDS             complement(3374..4063)
                     /locus_tag="VQ847_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3050976.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4081..4722)
                     /locus_tag="VQ847_001673"
     CDS             complement(4081..4722)
                     /locus_tag="VQ847_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3050977.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4805..5020)
                     /locus_tag="VQ847_001674"
     CDS             complement(4805..5020)
                     /locus_tag="VQ847_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3050978.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5028..5375)
                     /locus_tag="VQ847_001675"
     CDS             complement(5028..5375)
                     /locus_tag="VQ847_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3050979.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5380..6495)
                     /locus_tag="VQ847_001676"
     CDS             complement(5380..6495)
                     /locus_tag="VQ847_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3050980.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6505..7464)
                     /locus_tag="VQ847_001677"
     CDS             complement(6505..7464)
                     /locus_tag="VQ847_001677"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3050981.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7577..8146)
                     /locus_tag="VQ847_001678"
     CDS             complement(7577..8146)
                     /locus_tag="VQ847_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3050982.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8274..8945
                     /locus_tag="VQ847_001679"
     CDS             8274..8945
                     /locus_tag="VQ847_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3050983.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8929..9747
                     /locus_tag="VQ847_001680"
     CDS             8929..9747
                     /locus_tag="VQ847_001680"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3050984.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9744..10640
                     /locus_tag="VQ847_001681"
     CDS             9744..10640
                     /locus_tag="VQ847_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3050985.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10684..11658
                     /gene="pta"
                     /locus_tag="VQ847_001682"
     CDS             10684..11658
                     /gene="pta"
                     /locus_tag="VQ847_001682"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3050986.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11974..12762)
                     /locus_tag="VQ847_001683"
                     /pseudo
     CDS             complement(11974..12762)
                     /locus_tag="VQ847_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3727 a         2425 c         2741 g         3869 t
ORIGIN      
        1 agataaggct tataaccatg cgctatctaa ggagagaagc aaggttgaga acatctttgc
       61 caaagtaaaa acgtttaaaa tgttttcaac aacttatcga aatcatcgta aacgcttcgg
      121 attacgaatg aattttattg ctggtattat caatcatgaa ctaggattct agttttgcag
      181 gaagtctatt gaggtattga gctagtttat gaaaaaattg ggtgaaaagt cgagtgtttt
      241 agaaacccac agtgtagtat tctagtttca atccactata ttttgctact ccccgtaaag
      301 tttctatttt ccctgatttc tgatataata gaaatattga cttcaagagt aaggaagaga
      361 agatgaacgc attattaaat ggaatgaatg accgtcaggc tgaggcggtg caaacgacag
      421 aaggtccctt gctaatcatg gcaggggctg gttctggaaa gactcgtgtt ttaacccacc
      481 gtatcgctta tttgattgat gaaaagctgg tcaatccttg gaatatcttg gccattacct
      541 ttaccaacaa ggctgcgcgt gagatgaaag agcgtgctta tagcctcaat ccagctactc
      601 agaactgtct gattgcgacc ttccactcca tgtgtgtgcg tattttgcgt cgcgatgcgg
      661 accatattgg ctacaatcgt aattttacaa ttgtggatcc tggtgaacag cgaacgctca
      721 tgaaacgtat tctcaaacag ttgaacttgg atcctaaaaa atggaatgaa cgaactattt
      781 tggggaccat ttccaatgct aagaatgatt tgattgatga tgttgcttat gctgcccaag
      841 ctggcgatat gtatacgcaa attgtggccc agtgttatac agcctatcaa aaagaacttc
      901 gtcagtctga atccgttgac tttgatgatt tgattatgct gaccttgcgt ctctttgatc
      961 aaaatcctga tgttttaacc tactaccagc aaaaattcca atacatccac gttgatgagt
     1021 accaagatac caaccacgct cagtaccaat tggtcaaact cttggcttcc cgttttaaaa
     1081 atatctgtgt ggttggggat gcggaccagt ctatctacgg ttggcgtggt gctgatatgc
     1141 agaatatctt ggactttgaa aaggattacc ccaaagccaa ggttgttttg ttggaggaaa
     1201 attaccgctc aaccaaaacc attctccaag cggccaacga ggttattaaa aacaataaaa
     1261 atcgccgtcc taaaaatctc tggactcaaa acgctgatgg ggagcaaatc gtttactatc
     1321 gtgccgatga tgagctggat gaggctgtat ttgtagccag aaccatcgat gaacttagtc
     1381 gcagtcaaaa cttccttcat aaggattttg cagttctcta tcggactaat gcccagtccc
     1441 gtacaattga ggaagccctg ctcaagtcta acattcctta taccatggtt ggcggaacca
     1501 aattctacag ccgtaaggaa attcgcgata ttattgctta tctcaacctt attgctaatt
     1561 tgagtgacaa tattagtttt gagcgtatta tcaacgagcc taaacgtgga attggtccag
     1621 gtacagttga gaaaatccgt gattttgcaa atttgcaaaa tatgtctatg ctggatgctt
     1681 ctgctaatat tatgttgtct ggtatcaagg gtaaggcagc ccaatctatc tgggattttg
     1741 ccaatatgat gcttgatttg cgggagcagc tagaccactt aagcattaca gagttggttg
     1801 agtccgtcct agaaaaaaca ggttatgtcg atattcttaa cgcccaagcg actctagaaa
     1861 gcaaggcacg ggttgaaaat atcgaagagt ttctttctgt tacgaagaac tttgatgaca
     1921 ccactgatgt gacagaagag gaaactggtc tggacaaact gagtcgtttc ttaaatgact
     1981 tggctttgat tgccgacaca gattcaggta gtcaggagac atcagaagtg accttgatga
     2041 ccctgcatgc tgccaaaggt ctcgaatttc cagttgtctt tttgattggg atggaagaaa
     2101 atgtctttcc acttagtcgt gcgactgaag atacagatga attagaagaa gagcgccgtc
     2161 tagcctatgt aggtatcacg cgtgcagaga aaattctcta tctgaccaat gccaactcac
     2221 gcttgctttt tggtcgtacc aattataacc gtccgactcg ttttattaac gaaatcagtt
     2281 cagacttgct tgagtatcaa ggtctggctc gtcctgcaaa tacaagcttt aaggcatcat
     2341 atagcagtgg tagtatttcc tttggtcaag gtatgagttt ggctcaggct cttcaagacc
     2401 gtaaacgcgg tgctgcccca aaatcaatcc agtcaagcgg tcttccattt ggtcaattta
     2461 cagctggcgc aaaatcagca tctagcgagg caaattggtc cattggtgac attgctctcc
     2521 acaagaaatg gggagaggga actgttctgg aagtttcagg tagcggtgct aggcaggaat
     2581 tgaaaatcaa tttcccagaa gtaggtttga aaaaactttt agccagtgtg gctccaattg
     2641 agaaaaaaat ctaattttcc atccttctca cgaataataa agtgaggagg atttttatgt
     2701 acagtatttc attccaagaa gattcactat taccaagaga aaggctggcc aaggaaggag
     2761 ttgaagcgct tagtaaccaa gagttgctag ctattttact caggacagga acacgtcaag
     2821 ctagcgtttt tgaaattgcc caaaaagtct tgaacaatct ttcaagccta acggatttga
     2881 aaaaaatgac cctgcaggaa ttgcagagtt tgtctggtat tgggcgtgtt aaggccatag
     2941 aattacaagc tatgattgaa ctggggcatc gtattcacaa acacgagact cttgaaatgg
     3001 aaagtattct cagcagtcaa aagttggcca agaagatgca gcaggaatta ggggataaaa
     3061 aacaagagca cctggtggca ctctatctca atactcaaaa tcaaatcatc catcagcaga
     3121 ccatttttat cggttctgta actcgtagta tcgctgaacc gcgagagatt ctgcactatg
     3181 caatcaagca tatggcgact tctcttatct tggtccacaa tcatccttca ggagcggtag
     3241 cgcctagcca aaatgatgat catgtcacta aacttgttaa agaagcctgc gaactgatgg
     3301 ggattgttct cttggaccat ttgattgtct ctcattctaa ttactttagt tatcgtgaaa
     3361 agacagattt aatctaaagt tcattaacga catagtcaaa gagtttttta tctttgggac
     3421 gattttcaaa aagaagttct ggatgccatt ggacaccgag aaaggcgaca tcatccgtac
     3481 tcatgacagc ctcaatgata ccatctttag gatcatgagc cacaactttt aaatttggtg
     3541 ctaagtcctt gatgctctgg tggtggaagg agttgatatg agagatttct ccatagattt
     3601 cttggagaac ggtatctggt tctgtcacca agcgttgagt tgtgtactca acagaagaat
     3661 cctgccaatg gtcttcgata tcttggtaca aagttccacc catggcaacg ttaaagagtt
     3721 gggtaccacg gcagacagag aaaatgggct ttttctgttt aatagcttcc ttgatgaggg
     3781 ccagttcgaa gatatctctt tgaaggtgat agtcatcgct atcaatggtt ttgggttcgc
     3841 catagaattt tggatcgaca ttttgcccac ctgtcaagat gagcttgtca atcaaactga
     3901 tatagtggca ggccatttct tgatcaccaa tcggtaggat gatgggaatc cctccagcat
     3961 ctttaacgcc ttcaacaaag ccttttgctg cgtagctcat catgatgtca tcatctggat
     4021 gagttttttc gtttcctgta atcccaataa ctggtttttt cataaaatga ttttcgcttt
     4081 ctaatcctct tttcgcatga agtagaggag ggtttggagt tcacttgtca aatcgacata
     4141 ctgaacgacc acgtcttttg gtaaatgcag atggactggt gaaaaactga gaattccttt
     4201 cacaccagca tcaaccaaga gattagcaac ctcttgtgac ttgacgctgg gaacagttag
     4261 gatagcagtc ttcacatcag catccttgat tttatccttg atctgagaaa ttccgtaaat
     4321 gggaatcccg tcaggagttt gggtaccgac ttcaggatgg tcatctaggt caaaggccat
     4381 gataatcttc atcttgttac gttcgtggaa gcggtagtgg agaagggcat ggcccatatt
     4441 tccaatacca accagcatga cattggtaat agagttgtca ttgagcaaat cggcaaaaaa
     4501 tgtcattagt tttttgacat catatccaaa accacgacga ccaagttcac caaaatagga
     4561 aaaatcacga cgtacggtcg ctgaatcaat accgatagcc tctgcaattt gcttagagtt
     4621 ggcacgttca atcttttctg catgaaatct cttaaaaatt cgatagtaga gagagagtct
     4681 ttttgctgta gcttttggaa tagcaaactg tttatctttc acaaaatcac aacctttcta
     4741 ttcttctatt ttatagaaac attgtgaaaa aatcaacaaa aataagaaaa aactaagaaa
     4801 aatcttagtt ttgatgtaaa aaatctgcat gagatagaaa acggtagagg tctccgacca
     4861 gaccctgata aactttttgg cccctaaaag tcagagaagt cacataaagt gtatctggta
     4921 aggttacaca tcctgacaaa gtcaacatga gagcctcatg atcctcatac ttgagagtac
     4981 gctctacatg atagcagtcc ttataggtca gttcaaacat tttggctcta tctttccgat
     5041 tttgtaaaga caccacgttc taccaagcta tccatgagga agtagaattt ttcctgatga
     5101 atatggtggt cttctgattt gaaaatatca actagacgaa ggccaaactt atcagtgata
     5161 ttgattttag cccctgtaag ttccttgtta atgatgattt tgagttggaa gccttcaccg
     5221 ctgtttggca ctttttccaa aaggcgagtc agttcatagt taccaacctt agtttcaaaa
     5281 aaggtgttat ctttgagggt gaatttttta acagaagggc taagagtgta atcgtaacga
     5341 caatttttta actgaatgat tttttcaaat gccatatggc taacctccga taatttcttt
     5401 taaggttttt gcgagggttt gtaggtcttc aacggtattt tgtggcgaca aactgatgcg
     5461 aagggattcc ttcaagcgtt ctgaatttgc gccatacatg gcttcaagaa catggctgga
     5521 ttggacaacg cctgcagtac aggctgagcc agtagagatt gaaattccag ctaaatctag
     5581 ccgaaggagt aagaggtcat ttttctgacc aggaaatcca atattgagaa cataagggag
     5641 atgatgtttt cctctattca agtaatactg aatgccctcc agctctgcca gaaaggcagt
     5701 ttctagattt tgtacatgtt gaaaatgttc ttcttgtttt tctaggtctt cttttagggc
     5761 tgcaaccatg cctacgatag caggcagatt ttcagttcct gcacgttttt tctgttcctg
     5821 gtctccgcca tgtagatagg aatcaaagtc catgctagat gcgtagagaa aaccgattcc
     5881 cttaggacca tggaatttgt gggcagaagc agtgagaaaa tcaatgccca attcttctga
     5941 atgaattggg attttaccaa tagcctgaac tgcatcaaca tgataggcag cagggtgttg
     6001 cttgagtatt tggccaattt cagcgatggg cagtaggttt cctgtctcat tattggtaaa
     6061 catggtagaa accaaaatcg tatcgtcacg taaagccttt tgaatttgct gggctgtgat
     6121 ttcttgattt tctggctgga taatggttgc ttcaaaccca aagtgttgaa ccaagtaatc
     6181 aattgtttca aggacagcat ggtgctcgat ggcagttgtg atgatatgtt ttccttgttc
     6241 ttggtgacga agacagtagc caatgatggt agtattattg ccttcagtcc caccagaagt
     6301 gaaaaagata tgttgaggtt ttgtccttag taactgggct agttcctgac gggcttctcg
     6361 caagagtttg ccagcttgac gaccatgacc atgaatacta gaaggatttc cgtgggtttc
     6421 ttgcataacc ttggtcatag ctgaaatagc aactgctgac ataggagtcg ttgcagcatt
     6481 gtccaaataa atcaaagaat caccttattt ctttttattg taggcaaaga gtgggctgac
     6541 tggttttctt tcgtgaatac gtacgatagc atcaccaatt aactcactag cagtgatata
     6601 gcatacattt ttaggagttt tttcttttgt tgctactgaa tcagtcacaa gaatttcttt
     6661 aatattagta ttgtcaagaa gctcagcagc tccctcgacg aagagaccgt ggctagaaac
     6721 agcataaatt tctgtagctc cttcacgttc aacgatttta gaagcttcag agaaggtacg
     6781 tcctgtattt aaaatatcat caatcaagat agctttctta ccttcaacat caccaataat
     6841 ataaccttcg ttacgagttg catcgtcttg agggtagtcg ataatggcga taggagcatc
     6901 aagatattca gccaggctac gcgcacgttt gacacctgaa tttttagggc taacgacaac
     6961 aacatctgaa ccaagcaatc ctttatcgca gtaatgtttt gcgaataggg gaacagtgaa
     7021 aagattatcc actggaatat caaagaaacc ttgaacctga acggcatgca aatcaagagt
     7081 caggatacga tcaactccag ccttaaccag catattggca actagttttg ctgtaagtgg
     7141 ctcacgagga caagcaatgc ggtcttgacg tgcatagcca aaatatggaa ggacaacgtt
     7201 gatactgtgg gcacttgcac gcacacaagc atcgaccatg attaacaatt ccattaggtg
     7261 gttgttgaca gggaaacttg ttgattggat gatgtaaaca tcataaccac ggacactttc
     7321 ttcgatattt acttggattt ctccgtctga aaattgacgt gatgatagtt ttccaagtgg
     7381 gacaccaaca gcttgggcaa ttttttgtgc aatctcttgg ttagagttga gtgcgaaaag
     7441 tttcatgttt tttctatctg acattataga ccgtcctctg taaactttat aaatcctagt
     7501 tatatttacc ttacatatat gaactgggat ttgtgtattt ttatcttttc tattttacca
     7561 aaaaatggag attatttcag ctatttttca tacttttgac aaatcgaacc aattttgaag
     7621 gagctttttg gtaggaaatc tgatttttct ctaaaaattg tcggaaatcc tgtttgcctt
     7681 gctcatgatt ttccacttca agctccaatt cgtaatctgt tatatcaaag tatcggctct
     7741 gatccagtgc catgagacca atagctgttt tcatttcata gcgaagcgtt gttagacaac
     7801 caagaacctg ccagttctta ctttggatac catgtttcgc caattcatcc agtactagtc
     7861 cttgaggaag ttcttcctta ctcagatagt cctcagcatc ttttagttgc aatttttggt
     7921 tgtattccat gtttccaaca ctctgcggga ctttgagtgt caactcagcc cagtcttcaa
     7981 aggttcgaat gcgcatagcg actttctttt ctcgcagttc aaaatcaggc gtgtcgatgt
     8041 agtaatttgt ttgaagaaca ggagtgacac ctgtgaactg gtcttttaga cgattgtatt
     8101 catctttttt caatagtgtt ttcaattcaa tttctaaatg tttcattttt cttacctttt
     8161 tttatcgttg aaagcggatt tatggtataa taagcattgt atttattgta tatgaatctg
     8221 gagaaaaaat caaagatatt tttgacggat aatatgagaa caagggagaa tatatgacct
     8281 tagaatggga agaatttcta gatccttaca ttcaagctgt tggtgagtta aagattaaac
     8341 ttcgtggtat tcgtaagcaa tatcgtaagc aaaataagca ttctccaatt gagtttgtga
     8401 ccggtcgagt caagccaatt gagagcatca aagaaaaaat ggctcgtcgt ggcattactt
     8461 atgcgacctt ggaacacgat ttgcaggata ttgctggctt acgtgtgatg gttcagtttg
     8521 tagatgacgt caaggaagta gtggatattt tgcacaagcg tcaggatatg cgaatcatac
     8581 aggagcgaga ttacattact catagaaaag catcaggcta tcgttcctat catgtggtag
     8641 tagaatatac ggttgatacc atcaatggag ctaagactat tttggcagaa attcaaattc
     8701 gtactttggc catgaatttc tgggcaacga tagaacattc tctcaactac aagtaccaag
     8761 gggatttccc agatgagatt aagaagcgac tggaaattac agctagaatc gcccatcagt
     8821 tggatgaaga aatgggtgaa attcgtgatg atatccaaga agcccaggca ctttttgatc
     8881 ctttgagtag aaaattaaat gacggtgtag gaaacagtga cgatacagat gaagaataca
     8941 ggtaaacgaa ttgatctgat agccaataga aaaccgcaga gtcaaagggt tttgtatgaa
     9001 ttgcgagatc gtttgaagag aaatcagttt atactcaatg ataccaatcc ggatattgtc
     9061 atttccattg gcggggatgg tatgctcttg tcggcctttc ataagtacga aaatcagctt
     9121 gacaaggtcc gctttatcgg tcttcatact ggacatttgg gcttctatac agattatcgt
     9181 gattttgagt tggacaagct agtgactaat ttgcagctag atactggggc aagggtttct
     9241 taccctgttc tgaatgtgaa ggtctttctt gaaaatggtg aagttaagat tttcagagca
     9301 ctcaacgaag ccagcatccg caggtctgat cgaaccatgg tggcagatat tgtaataaat
     9361 ggtgttccct ttgaacgttt tcgtggagac gggctaacag tttcgacacc gactggtagt
     9421 actgcctata acaagtctct tggcggtgct gttttacacc ctaccattga agctttgcaa
     9481 ttaacggaaa ttgccagcct taataatcgt gtttatcgaa cactgggctc ttccattatt
     9541 gtgcctaaga aggataagat tgaacttatt ccaacaagaa acgattatca tactatttcg
     9601 gttgacaata gcgtttattc tttccgtaat attgagcgta ttgagtatca aatcgaccat
     9661 cataagattc actttgtcgc gactcctagc cataccagtt tctggaaccg tgttaaggat
     9721 gcctttatcg gtgaggtgga tgaatgaggt ttgaatttat cgcagatgaa catgtcaagg
     9781 ttaagacctt tttaaaaaag cacgaggttt ctaagggatt gctggctaag attaagtttc
     9841 gaggtggagc tattctggtc aataatcaac cgcaaaatgc aacgtatcta ttggacgttg
     9901 gagactacgt taccatttac attcccgctg aggaaggctt tgaaaccttg gaggctattg
     9961 agcatccatt agatattctc tatgaggatg accactttct agtcttgaat aaaccctatg
    10021 gagtggcttc tattcctagt gtcaatcact ctaacaccat tgccaatttt atcaagggtt
    10081 actatgtcaa gcaaaattat gaaaatcagc aggttcacat tgttaccaga ctagataggg
    10141 acacttctgg cttgatgctc tttgccaagc acggttatgc ccatgcacga ttagacaagc
    10201 agttgcagaa gaaatctatc gagaaacgct actttgcttt ggttaaggga gatggacatt
    10261 tggagccaga aggggaaatt attgctccga ttgcgcgtga tgaagattcc attattacca
    10321 gacgagtggc taaaggcgga aagtatgccc atacttcata caagattgta gcttcttatg
    10381 gaaatattca cttggtctat attcacctgc acactggtcg aacccatcaa atccgagtcc
    10441 atttttctca tatcggtttt cctttgctgg gagatgattt gtatggtggt agtctggaag
    10501 atggtattca acgtcaggct ctgcattgcc attacctatc cttttatcat ccatttttag
    10561 agcaagactt gcagttagaa agtcccttgc cggatgattt cagtaacctt attacccagt
    10621 tatcaactaa tactctataa aaactgtctc agagtataat tattatctta aaggagaaaa
    10681 ctcatggaag tttttgaaag tctcaaagcc aaccttgttg gtaaaaatgc tcgtatcgtt
    10741 ctccctgaag gggaagagcc tcgtattctt caagcaacaa aacgcttagt aaaagaaaca
    10801 gaagtgattc ctgttttgct tggaaatcct gaaaaaatta aaatttatct tgaaattgaa
    10861 ggaatcatgg atggttatga ggtcatcgac cctcaacatt atcctcaatt tgaagaaatg
    10921 gtttctgcct tggtggagcg tcgcaagggc aaaatgactg aagaagatgt acgcaaggtt
    10981 ttggttgaag atgtcaacta ctttggtgtg atgttggttt acttgggctt ggttgatgga
    11041 atggtgtcag gagcgattca ctcaacagct tcaacagttc gtccagctct acaaatcatc
    11101 aaaactcgtc caaatgtaac tcgtacttca ggagccttcc tcatggttcg tggtacggaa
    11161 cgttacctat ttggagactg tgccattaac atcaatccag atgcagaagc cttggctgaa
    11221 attgccatca actcagcaat cacagctaag atgtttggca tcgaacctaa aattgccatg
    11281 ttgagctatt ctactaaagg ttcagggttt ggtgaaagcg ttgataaggt cgttgaagca
    11341 actaaaattg ctcacgactt gcgtcctgac cttgaaatcg atggtgagtt gcaatttgat
    11401 gcagcctttg ttcctgaaac tgcagctctg aaagctcctg gaagtacggt agctggtcaa
    11461 gcaaatgtct tcatcttccc aggtatcgag gccggaaata tcggttacaa gatggctgaa
    11521 cgcctgggtg gctttgcggc tgtaggacct gttttgcaag gtttaaacaa gccagttaat
    11581 gatctttctc gtggatgtaa tgcagatgat gtttacaagt tgaccctcat cacagcagct
    11641 caagcagttc atcaatagtg aaaactataa agcgatatac tatgctatac tgtagttatg
    11701 aaactatgta cgaaaagcac tgccattaat tcctgagaac taaattactg attggtgtca
    11761 aaaaggaaaa cttccaagcg atgatatcct gtctatacac gacctataga aatctgtaat
    11821 atgtatgtcc gtaaaacgat aatttccctt tttgatttta aatgagtatg aaaagagaat
    11881 tttttcatga gaaaacgcat aatattaagt gtcttgacac ctgctattat gcgttttctg
    11941 gctctttgtc aactgtagtg ggttgaagaa aagctaagct cgagaaagga caaattttgt
    12001 cctttctttt ttgatattca gagcggtaaa aatccgtttt ttgaagtttt caaagttccg
    12061 aaaaccaaag gcattgcgct tgataagttt gatgagatta ttggtcgctt ccaatttggc
    12121 gtttgaatag ggtagttgaa gggcgttgac gattttctct ttgtccttta gaaaggtttt
    12181 aaagacagtc tgaaaaagag gatgaacctg ctttagattg tcctcaatga gtccgaaaaa
    12241 tttctccggt tccttattct gaaagtgaaa cagcaagagt tgatagagct gatagtgatg
    12301 tttcaagtct tgtgaatagc tcaaaagctt gtctaaaatc tctttattgg ttaaatgcat
    12361 acgaaaagta ggacgataaa atcgcttatc actcagttta cggctatcct gttgaatgag
    12421 tttccagtag cgcttgatag ccttgtattc atgggatttc ggatgatggc ttgtgttctg
    12481 ctctcaagaa cagttatgat attgagctta tcaaagtcct gagcaataaa gctcatctcc
    12541 atctcccgat tgaaacagtc actccccgga ctgtttcaac gtcccaagac ataatctcag
    12601 gaagacgcga aaaatcatgc tcaaagtgaa aatcattgag cttacgaata acagttgaag
    12661 ttgagatgga aagctgatgg gcaatatcag tcatagaaat cttttcaatt aacttttgag
    12721 caatcttttg gttgatgata cgagggattt ggtgattctt ct
//
LOCUS       DAVBNN010000055        12573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBNN010000055 DAVBNN010000000
VERSION     DAVBNN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.055"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQ847_001684"
     CDS             complement(251..433)
                     /locus_tag="VQ847_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050987.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQ847_001685"
     CDS             complement(649..1881)
                     /locus_tag="VQ847_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3050988.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ847_001686"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ847_001686"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3050989.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQ847_001687"
     CDS             complement(3048..4217)
                     /locus_tag="VQ847_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3050990.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQ847_001688"
     CDS             complement(4403..5707)
                     /locus_tag="VQ847_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3050991.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQ847_001689"
     CDS             complement(5824..6978)
                     /locus_tag="VQ847_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3050992.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQ847_001690"
     CDS             complement(6975..7526)
                     /locus_tag="VQ847_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3050993.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQ847_001691"
     CDS             complement(7519..8655)
                     /locus_tag="VQ847_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3050994.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ847_001692"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ847_001692"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3050995.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ847_001693"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ847_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3050996.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQ847_001694"
     CDS             complement(10172..10903)
                     /locus_tag="VQ847_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3050997.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQ847_001695"
     CDS             complement(10905..12350)
                     /locus_tag="VQ847_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3050998.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4238 a         2433 c         1654 g         4248 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcatccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttt ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactacat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBNN010000056        11822 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBNN010000056 DAVBNN010000000
VERSION     DAVBNN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11822
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.056"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            389..616
                     /locus_tag="VQ847_001696"
     CDS             389..616
                     /locus_tag="VQ847_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3050999.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            904..3801
                     /gene="nanA"
                     /locus_tag="VQ847_001697"
     CDS             904..3801
                     /gene="nanA"
                     /locus_tag="VQ847_001697"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3051000.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4816..5268
                     /locus_tag="VQ847_001698"
     CDS             4816..5268
                     /locus_tag="VQ847_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3051001.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5287..6624
                     /locus_tag="VQ847_001699"
     CDS             5287..6624
                     /locus_tag="VQ847_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3051002.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6703..7587
                     /locus_tag="VQ847_001700"
     CDS             6703..7587
                     /locus_tag="VQ847_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3051003.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7587..8420
                     /locus_tag="VQ847_001701"
     CDS             7587..8420
                     /locus_tag="VQ847_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3051004.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8438..10531
                     /gene="nanB"
                     /locus_tag="VQ847_001702"
     CDS             8438..10531
                     /gene="nanB"
                     /locus_tag="VQ847_001702"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3051005.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10543..11646
                     /locus_tag="VQ847_001703"
     CDS             10543..11646
                     /locus_tag="VQ847_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3051006.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDVCKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVRLSEIVK"
BASE COUNT         3997 a         1844 c         2452 g         3529 t
ORIGIN      
        1 gtgttttgag ttgactttgt cagtcttatc tacagcctca aaacagtgtt ttgagcatca
       61 tgcggctagc ttcttagttt gctctttgat tttcattgag tataaaaaca gatgagtttc
      121 tgttttcttt ttatggacta taaatgttca gctgaaacta ctttcaagga cattattata
      181 taaaagaatt ttttgaaact aaaatctact atattacact atattgaaag cgttttaaaa
      241 atgaggtata ataaatttac taacacttat aaaaagtgat agaatctatc tttatgtata
      301 tttaaagata gattgctgta aaaatagtag tagctatgcg aaataacaga tagagagaag
      361 ggattgaagc ttagaaaagg ggaataatat gatatttaag gcattcaaga caaaaaagca
      421 gagaaaaaga caagttgaac tacttttgac agtttttttt gacagttttc tgattgattt
      481 atttcttcac ttatttggga ttgtcccctt taagctggat aagattctga ttgtgagctt
      541 gattatattt cccattattt ctacaagtat ttatgcttat gaaaagctat ttgaaaaagt
      601 gttcgataag gattgagcag gaagtatggt gtaaatagca taagctgatg tccatcattt
      661 gcttataaag agatatttta gtttaattgc agcggtgtcc tggtagataa actagattgg
      721 caggagtctg attggagaaa ggagagggga aaattggcac caatttgaga tagtttgttt
      781 agttcatttt tgtcatttaa atgaactgta gtaaaagaaa gttaataaaa gacaaactaa
      841 gtgcattttc tggagtaaat gtcttatttc agaaatcggg atatagatat agagaggatc
      901 agtatgaatc ggagtgttca agaacgtaag tgtcgttata gcattaggaa actatcggta
      961 ggagcggttt ctatgattgt aggagcagtg gtatttggaa cgtctcctgt tttagctcaa
     1021 gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac tttcggggga gagctcaacc
     1081 ctaactgata cagaaaagag ccagccttct tcagagactg aactttctgg caataagcaa
     1141 gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa gagattacta tgcacgagat
     1201 ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg aaaccaatgc ttcaaatggt
     1261 cagagagttg atttatcaag tgaactagat aaactaaaga aacttgaaaa cgcaacagtt
     1321 cacatggagt ttaagccaga tgccaaggct ccagcattct ataatctctt ttctgtgtca
     1381 agtgctacta aaaaagatga gtacttcact atggcagttt acaataatac tgctactcta
     1441 gaggggcgtg gttcggatgg gaaacagttt tacaataatt acaacgacgc acccttaaaa
     1501 gttaaaccag gtcagtggaa ttctgtgact ttcacagttg aaaaaccgac agcagaacta
     1561 cctaaaggcc gagtgcgcct ctacgtaaac ggggtattat ctcgaacaag tctgaaatct
     1621 ggcaatttca ttaaagatat gccagatgta acgcatgtgc aaatcggagc aaccaagcgt
     1681 gccaacaata cggtttgggg gtcaaatcta cagattcgga atctcactgt gtataatcgt
     1741 gctttaacac cagaagaggt acaaaaacgt agtcaacttt ttaaacgctc agatttagaa
     1801 aaaaaactac ctgaaggagc ggctttaaca gagaaaacgg acatattcga aagcgggcgt
     1861 aacggtaaac caaataaaga tggaatcaag agttatcgta ttccagcact tctcaagaca
     1921 gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc tccattcgag tgactggggt
     1981 gatatcggta tggtcatcag acgtagtgaa gataatggta aaacttgggg tgaccgagta
     2041 accattacca acttacgtga caatccaaaa gcttctgacc catcgatcgg ttcaccagtg
     2101 aatatcgata tggtgttggt tcaagatcct gaaaccaaac gaatcttttc tatctatgac
     2161 atgttcccag aagggaaggg aatctttgga atgtcttcac aaaaagaaga agcctacaaa
     2221 aaaatcgatg gaaaaaccta tcaaatcctc tatcgtgaag gagaaaaggg agcttatacc
     2281 attcgagaaa atggtactgt ctatacacca gatggtaagg cgacagacta tcgcgttgtt
     2341 gtagatcctg ttaaaccagc ctatagcgac aagggtgatc tatacaaggg taaccaatta
     2401 ctaggcaata tctacttcac aacaaacaaa acttctccat ttagaattgc caaggatagc
     2461 tatctatgga tgtcctacag tgatgacgac gggaagacat ggtcagcgcc tcaagatatt
     2521 actccgatgg tcaaagccga ttggatgaaa ttcttgggtg taggtcctgg aacaggaatt
     2581 gtacttcgga atgggcctca caagggacgg attttgatac cggtttatac gactaataat
     2641 gtatctcact taaatggctc gcaatcttct cgtgtcatct attcagatga tcatggaaaa
     2701 acttggcatg ctggagaagc ggtcaacgat aaccgtcagg tagacggtca aaagatccac
     2761 tcttctacga tgaacaataa acgtgcgcaa aatacagaat caacggtggt acaactaaac
     2821 aatggagatg ttaaactctt tatgcgtggt ttgactggag atcttcaggt tgctacaagt
     2881 aaagacggag gagtgacttg ggagaaggat atcaaacgtt atccacaggt taaagatgtc
     2941 tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa aagaatacat catcctcagt
     3001 aatgcaggtg gaccgaaacg tgaaaatggg atggtccact tggcacgtgt cgaagaaaat
     3061 ggtgagttga cttggctcaa acacaatcca attcaaaaag gagagtttgc ctataattcg
     3121 ctccaagaat taggaaatgg ggagtatggc atcttgtatg aacatactga aaaaggacaa
     3181 aatgcctata ccctatcatt tagaaaattt aattgggact ttttgagcaa agatctgatt
     3241 tctcctaccg aagcgaaagt gaagcgaact agagagatgg gcaaaggaga gatgggcaaa
     3301 ggagttattg gcttggagtt cgactcagaa gtattagtca acaaggctcc aacccttcaa
     3361 ttggcaaatg gtaaaacagc gactttccta acccagtatg atagcaagac cttgttattt
     3421 gcagtagata aggaagatat cggacaggaa attattggta tagctaaagg aagcatcgaa
     3481 agtatgcata atcttcctgt aaatctagca ggtgccagag ttcctggcgg agtaaatggt
     3541 agcaaagcag cggtgcatga agttccagaa tttacagggg gagttaatgg tacagagcca
     3601 gctgttcatg aaatcgcaga gtataaggga tctgattcgc ttgtaactct tactacaaaa
     3661 gaagattata cttacaaagc tcctcttgct cagcaggcac ttcctgaaac aggaaacaag
     3721 gagagtgacc tcctagcttc actaggacta acagctttct tccttggtct gtttacgcta
     3781 gggaaaaaga gagaacaata agagaagaat tctaaacatt tgattttgta aaaatagaag
     3841 gagatagcag gttttcaagc ctgctatctt tttttgatga cattcaagct gatacgaaat
     3901 cataagaggt ctgaaactac tttcagagta gtctgttcta taaaatatag tagattgaaa
     3961 taagatgtga acaactctat caggaaagtc aaattaattt atagaaaaat tttagcagtc
     4021 aaggtgtact gttatgtatt caatatatta tgcggctatt aaccttgtct tctcctaaaa
     4081 ttgactttct tgttttctta tcttgtccac tcgaaacaag tattgtaaga atttgattat
     4141 ttttgaaagt acttttaata tacttgatat agttaaaaaa gatttgaaac taaattccaa
     4201 attagaaaaa gacttgaaat actaaaaaaa aaaagtatac tctaattgaa aacggtaaca
     4261 aaactaattt agagaatgaa atatagagta tttctctctt aaaagttttt ggtgaaacga
     4321 gatgtagaaa ggagatttag ccaaagagtc tattagtgct agaataatag attagaatta
     4381 ttttagaaaa acgaagtgag cagcttataa attcaagtcc ccaaatagat tcatactagt
     4441 atcttttgca aaaaataaag ggcgacttcc ttcatgaata tcaatttcat ctataaggaa
     4501 ggtagctaat tgaactaact tatttattct gtttgtcgct agaaaaatca gacctccttg
     4561 tgaagattga ggagatactt aatgaaaatc aaagaagaaa ctagcaagct agtagcagat
     4621 tgcccaaaac accgctttga ggttgtagat aagactgacg tatataatcc aaggtgaagc
     4681 gactgtggtt tgaagagatt ttcaaagagt ataggctaga gagtagtgtt tttatgtcct
     4741 tctagtagaa aatgctagac agaagaatgg ggaacttgga taggaaaaat agattgagaa
     4801 aggaggttag aagagatgat tattacaaaa attagccgtt taggaactta tgtgggagta
     4861 aatccacatt ttgcaacatt aatagatttt ctagaaaaaa caggactaga aaatttaaca
     4921 gaaggttcga ttgctatcga tggtaatcga ttgtttggga attgctttac ttatctagca
     4981 gatggtcaag caggggcttt ctttgaaaca caccaaaaat atttggatat tcatttagtt
     5041 ttggaaaacg aagaagccat ggctgttaca tcgccggaaa atgtaagcgt tacccaagaa
     5101 tatgatgaag agaaagatat tgaattatac acagggaaag tggaacagtt ggttcatttg
     5161 agagctggcg aatgcctcat cacttttcca gaagatttac atcaacccaa ggttcgtata
     5221 aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga tttcttaatg tagaaagaga
     5281 agaacgatga aaaaaatgag aaagttttta tgtctagctg gaattgcgct agcggctgtt
     5341 gccttggtag cttgttcagg aaaaaaagaa gctacaacta gtactgaacc accaacagaa
     5401 ttatctggtg agattacaat gtggcactcc tttactcaag gaccccgttt agaaagtatt
     5461 caaaaatcag cagatgcttt catgcaaaag catccaaaaa cgaaaatcaa gattgaaaca
     5521 ttttcttgga atgacttcta tactaaatgg actacaggtt tagcaaatgg aaatgtgcca
     5581 gatatcagta cagctcttcc taaccaagta atggaaatgg tcaactcaga tgctttggtt
     5641 ccgttaaatg attctatcaa gcgtattgga caagataaat ttaacgaaac tgccttaaat
     5701 gaagcaaaaa tcggagatga ttactactct gttcctcttt attcacatgc acaagtcatg
     5761 tgggttagaa cagatttgtt aaaagaacat aatattgagg ttcctaaaac ttgggatcaa
     5821 ctctatgaag cttctaaaaa attgaaagaa gctggagttt atggcttgtc tgttccgttt
     5881 ggaacaaatg acttaatggc aacacgtttc ttgaacttct acgtacgtag tggtggagga
     5941 agcctcttaa caaaagatct taaagcagac ttgacaagcc aacttgctca agatggtatt
     6001 aaatactggg ttaaattgta taaagaaatc tcacctcaag attctttgaa ctttaatgtc
     6061 cttcaacaag ctaccttgtt ctatcaagga aaaacagcat ttgactttaa ctctggcttc
     6121 catatcggag gaattaatgc caacagtcct caattgattg attcgattga tgcttatcct
     6181 attccaaaaa tcaaagagtc tgataaagac caaggaattg aaacctcaaa cattccaatg
     6241 gttgtttgga aaaattcaaa acatccagaa gttgctaaag cattcttaga agcactttat
     6301 aatgaagaag actacgttaa attccttgat tcaactccag taggtatgtt gccaactatt
     6361 aaggggatta gcgattctgc agcctataaa gaaaatgaaa ctcgtaagaa atttaaacat
     6421 gctgaagaag taattactga agctgttaaa aaaggtactg ctattggtta tgaaaatgga
     6481 ccaagtgtac aagctggtat gttgactaac caacacatta ttgaacaaat gttccaagat
     6541 atcattacaa atggaacaga tcctatgaaa gcagcaaaag aagcagaaaa acaattaaat
     6601 gatttatttg aggctgttca gtagatgtaa aagactagaa aataggtggg ctagtgagct
     6661 gaaaagctct agcccaatct tgtaaaagaa gggagaagga gaatggttaa agaacgtaat
     6721 ttaactcgct ggatatttgt tttgccagct atgattatcg taggattact ctttgtttat
     6781 ccgtttttct cgagtatttt ttatagcttt accaataagc atttgattat gcctaattat
     6841 aaatttgttg gtttggctaa ctataaagct gtgctatcag atcccaactt ctttaatgcg
     6901 ttctttaatt caattaagtg gaccattttc tcattagttg gtcaagtttt agtagggttt
     6961 gtattggctt tagctcttca cagagtacgc cacttcaaga aattatatag gaccttattg
     7021 attgttcctt gggcatttcc taccatcgtt attgccttct cttggcagtg gattctaaac
     7081 ggggtttatg gctacttacc taatctaatc gtaaaattag gtttaatgga acatacacct
     7141 gcatttttga cagatagtac atgggcattc ctatgtttgg tgtttatcaa catttggttt
     7201 ggagcaccaa tgattatggt taatgtgctt tcagctttgc aaacagtacc agaagaacaa
     7261 tttgaggctg ctaagataga tggtgcttca agttggcagg tgttcaagtt tatcgtcttt
     7321 ccacatatta aagtggttgt aggacttcta gttgttttga gaactgtatg gatctttaat
     7381 aactttgaca ttatctacct cattactggt ggtggaccag ccaatgctac aacgacgctt
     7441 ccaatttttg cttacaacct gggctgggga actaaattgt tgggtcgtgc ttcagcagtt
     7501 acagtattgc tctttatctt cttggtggcg atttgcttta tctactttgc tatcatcagt
     7561 aagtgggaaa aggagggtag aaaataatga agaagaaatc cagtatttat ttagatattc
     7621 tctcacatgt acttttagtt ggtgcgacca tcgttgcaat tttcccattg gtatggatta
     7681 tcatatcttc tgtcaaaggg aaaggggaat taactcagta tccaacacga ttttggcctg
     7741 aacagtttac attagattat ttcactcatg ttatcaacga tttgcacttc attgataaca
     7801 ttcgaaacag tttaatcatt gccttggcta caacccttat tgcgattatt atttctgcta
     7861 tggcagccta tggtattgtt cgattctttc ctaaattggg agcaatcatg tcgagactac
     7921 tcgtcattac ctacattttc ccaccaattt tgttagcaat tccctattca attgccattg
     7981 ctaaagttgg gttaacaaat agtttatttg gcttgatgat ggtttatcta tcttttagtg
     8041 ttccatatgc agtttggctc ttagttggat ttttccaaac agttccaatt ggaattgaag
     8101 aagcggctag aattgatggt gcaaataaat ttgttacgtt ttataaagtt gtgctaccga
     8161 ttgtagcacc aggtattgta gcaacagcta tttatacatt tatcaatgct tggaatgaat
     8221 tcctgtatgc cttgattttg attaacaata caggaaagat gacagtagca gtagcccttc
     8281 gttcacttaa tggttcagaa atactagact ggggagatat gatggcagcg tctgttattg
     8341 tagttcttcc atcaattatt ttcttctcta tcatccaaaa taagattgca agtggattat
     8401 cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg aataaaagag gtctttattc
     8461 aaaactagga atttctgttg taggcattag tcttttaatg ggagttccca ctttgattca
     8521 tgcgaatgaa ttaaactatg gtcaactgtc catatctcct atttttcaag gaggttcata
     8581 tcaactgaac aataagagta tagatatcag ctctttgtta ttagataaat tgtctggaga
     8641 gagtcagaca gtagtaatga aatttaaagc agatgaacca aactctcttc aagctttgtt
     8701 tggcctatct aatagtaaag caggctttaa aaataattac ttttcaattt tcatgagaga
     8761 ttctggtgag ataggtgtag aaataagaga cgcccaaaag ggaataaatt atttattttc
     8821 tagaccagct tcattatggg gaaagcataa aggacaggca gttgaaaata cactagtatt
     8881 tgtatctgat tctaaagata aaacatacac aatgtatgtt aatggaatag aagtgttctc
     8941 tgaaacagtt gatacatttt tgccaatttc aaatataaat ggtatagata aggcaacact
     9001 aggagctgtt aatcgtgaag gtaaggaaca ttacctcgca aaaggaagta ttgatgaaat
     9061 cagtctattt aacaaagcaa ttagtgatca ggaagtttca aatattccct tgtcaaatcc
     9121 atttcagtta attttccaat caggagattc tactcaagct aactatttta gaataccgac
     9181 actatataca ttaagtagtg gaagagttct atcaagtatt gatgcacgtt atggtgggac
     9241 tcatgattct aaaagtaaga ttaatattgc cacttcttat agtgatgata atgggaaaac
     9301 gtggagtgag ccaatttttg ctatgaagtt taatgactat gaggagcagt tagtttactg
     9361 gccacgagat aataaattaa agaatagtca aattagtgga agtgcttcat tcatagattc
     9421 atccattgtt gaagataaaa aatctgggaa aacgatatta ctagctgatg ttatgcctgc
     9481 gggtattgga aataataatg caaataaagc cgactcaggt tttaaagaaa taaatggtca
     9541 ttattattta aaactaaaga agaatggaga taacgatttc cgttatacag ttagagaaaa
     9601 tggtgtcgtt tatgatgaaa caactaataa acctacaaat tatactataa atgataagta
     9661 tgaagttttg gagggaggaa agtctttaac agtcgaacaa tattcggttg attttgatag
     9721 tggctcttta agagaaaaac ataatggaaa acaggtccca atgaatgttt tctacaaaga
     9781 ttcgttattt aaagtgactc ctactaatta tatagcaatg acaactagtc agaatagagg
     9841 agagagttgg gaacaattta agttgttgcc tccgttctta ggagaaaaac ataatggaac
     9901 ttacttatgt cccggacaag gtttagcatt aaaatcaagt aacagattga tttttgcaac
     9961 atatactagt ggagaactaa cctatctcat ttctgatgat agtggtcaaa catggaagaa
    10021 atcctcagct tcaattccgt ttaaaaatgc aacagcagaa gcacaaatgg ttgaactgag
    10081 agatggtgtg attagaacat tctttagaac cactacaggt aagatagctt atatgactag
    10141 tagagattct ggagaaacat ggtcggaagt ttcgtatatt gatggaatcc aacaaacttc
    10201 atatggcaca caagtatctg caattaaata ctctcaatta attgatggaa aagaagcagt
    10261 cattttgagt acaccaaatt ctagaagtgg ccgtaaggga ggtcaattag ttgtcggttt
    10321 agtcaataaa gaagatgata gtattgattg gaaataccac tatgatattg atttgccttc
    10381 gtatggttat gcctattctg cgattacaga attgccaaat catcacatag gtgtactgtt
    10441 tgaaaaatat gattcgtggt cgagaaatga attgcattta agcaatgtag ttcagtatat
    10501 agatttggaa attaatgatt taacaaaata aaggagaaaa acatggttaa atacggtgtt
    10561 gttggagcag ggtattttgg agctgaattg gctcgctaca tgcaaaaaaa tgatggagca
    10621 gagattactc ttctctatga tccagataat gcagaggcga ttgcagaaga attgggagca
    10681 aaagtagcaa gttccttaga tgagttggtt tctagcgatg aagtagactg tgttatcgtc
    10741 gcaactccaa ataatcttca taaggaaccg gttattaagg ctgcacagca tggtaaaaat
    10801 gttttctgtg aaaaaccaat tgcgctttct tatcaagatt gtcgcgagat ggtagatgtg
    10861 tgtaaagaaa acaatgtaac ctttatggca ggacatatta tgaatttctt taatggtgtt
    10921 catcatgcaa aagaactcat taatcaagga gttatcggag acgttctata ttgtcataca
    10981 gctcgtaatg gttgggaaga acaacaaccg tcagtatcat ggaaaaaaat tcgtgaaaaa
    11041 tcaggtggtc acttgtatca ccacatccat gaattggatt gcgttcaatt ccttatgggg
    11101 ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg cccatgaagg tgaacatttc
    11161 ggtgatgaag atgatatgat ttttgtcaat atggaatttt ctaataagcg ttttgctttg
    11221 ttagaatggg gttcagctta tcgttggggt gaacattatg tcttaatcca aggaagcaaa
    11281 ggtgccatcc gcttagactt attcaactgt aaaggaactc ttaagctaga tgggcaagaa
    11341 agctatttct tgattcacga atcgcaagaa gaagatgatg atcggactcg tatctatcat
    11401 agtacagaga tggatggagc aattgcttat ggtaaaccag gtaaacgtac tccattatgg
    11461 ctatcatctg tcattgataa agaaatgcgc tatctgcatg agattatgga aggagctcca
    11521 gtatcagaag aatttgcaaa acttttgaca ggtgaagctg ccctagaagc aattgctact
    11581 gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag taagattgtc agaaattgta
    11641 aaataaattt tggtattctc ctatctatag gtcgacttgc tcctctgaaa gtacttttag
    11701 aggagctgtt tgactttgct agtttttgaa actgaaatct attatactac aaactattga
    11761 aagcgtttta attttaaggt ataataatct catagaaata aagaaaagga ggaaagagga
    11821 tg
//
LOCUS       DAVBNN010000057        11714 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBNN010000057 DAVBNN010000000
VERSION     DAVBNN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.057"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ847_001704"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ847_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3051007.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ847_001705"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ847_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3051008.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ847_001706"
     CDS             complement(2411..2905)
                     /locus_tag="VQ847_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3051009.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ847_001707"
     CDS             complement(2902..3366)
                     /locus_tag="VQ847_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3051010.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAENQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ847_001708"
     CDS             complement(3376..4710)
                     /locus_tag="VQ847_001708"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3051011.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ847_001709"
     CDS             complement(4721..5338)
                     /locus_tag="VQ847_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3051012.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ847_001710"
     CDS             complement(5386..8484)
                     /locus_tag="VQ847_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3051013.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ847_001711"
     CDS             complement(8577..9743)
                     /locus_tag="VQ847_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3051014.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ847_001712"
     CDS             complement(9751..10845)
                     /locus_tag="VQ847_001712"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3051015.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ847_001713"
     CDS             complement(11003..11656)
                     /locus_tag="VQ847_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3051016.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3253 a         2679 c         2220 g         3562 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgattt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atgg
//
LOCUS       DAVBNN010000058        11445 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBNN010000058 DAVBNN010000000
VERSION     DAVBNN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.058"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..127
                     /locus_tag="VQ847_001714"
     CDS             <1..127
                     /locus_tag="VQ847_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051017.1"
                     /translation="MKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(357..1337)
                     /gene="dusB"
                     /locus_tag="VQ847_001715"
     CDS             complement(357..1337)
                     /gene="dusB"
                     /locus_tag="VQ847_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3051018.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1324..2196)
                     /gene="hslO"
                     /locus_tag="VQ847_001716"
     CDS             complement(1324..2196)
                     /gene="hslO"
                     /locus_tag="VQ847_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3051019.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2361..3788
                     /locus_tag="VQ847_001717"
     CDS             2361..3788
                     /locus_tag="VQ847_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3051020.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3947..5455
                     /gene="glpK"
                     /locus_tag="VQ847_001718"
     CDS             3947..5455
                     /gene="glpK"
                     /locus_tag="VQ847_001718"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3051021.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEIDD"
     gene            5602..7428
                     /gene="glpO"
                     /locus_tag="VQ847_001719"
     CDS             5602..7428
                     /gene="glpO"
                     /locus_tag="VQ847_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3051022.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7498..8202
                     /locus_tag="VQ847_001720"
     CDS             7498..8202
                     /locus_tag="VQ847_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3051023.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8499..8702
                     /locus_tag="VQ847_001721"
     CDS             8499..8702
                     /locus_tag="VQ847_001721"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051024.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8789..9049)
                     /locus_tag="VQ847_001722"
     CDS             complement(8789..9049)
                     /locus_tag="VQ847_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051025.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(9104..9448)
                     /locus_tag="VQ847_001723"
     CDS             complement(9104..9448)
                     /locus_tag="VQ847_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051026.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            10487..>11445
                     /gene="ltrA"
                     /locus_tag="VQ847_001724"
     CDS             10487..>11445
                     /gene="ltrA"
                     /locus_tag="VQ847_001724"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3051027.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         3390 a         2225 c         2608 g         3222 t
ORIGIN      
        1 tatgaaagca agccaatggt tcaaagtatc agataaatgg tactatgtca atggctcagg
       61 tgcccttgca gtcaacacaa ctgtagatgg ctatggagtc aatgccaatg gtgaatgggt
      121 aaactaaacc taatataact agttaatact gacttcctgt aagaactctt taaagtattc
      181 cctacaaata ccatatcctt tcagtagata atataccctt gtaggaagtt tagattaaaa
      241 aataactctg taatctctag ccggatttat agcgctagag actacggagt ttttttgatg
      301 aggaaagaat ggcggcattc aagaggctct ttaagagagt tacaggtttt aaactattaa
      361 gccttctcca attgcaagag ggcttcaatc tctgctaggg tgctagcttg cgaaatggct
      421 ccacggagtt tggcagcgcc agatgttcca cggagatagt gaggagcgag gccgcggaat
      481 tcacgaactg cgacgttttc tcctttgagg ttaatcaatc gtttcaagtg ttcgtaggcg
      541 atcttcatct tgtcttcaaa tgtcaaatca ggtaggattt ctcctgtttc aaagtaatgg
      601 ttgatttggt tgaagaggta aggatttccc atggcagctc ggccaatcat gactgcgtca
      661 gcaccaactt cttcgatgcg ttgcttggct tcttggacag tacggatatc accgttggcg
      721 atgaatggaa tcttggttag agcttgggca accttgtaaa gggtctcaag gtccgcgtgg
      781 ccagtataca tttgttcacg ggtacggcca tgcatggcga gggcagaaac acctgcagcc
      841 tcagcagcga gggcattttc tactgcaaga gatgggtccg cccagccggt acgcattttg
      901 acagtaagtg ggatatcaag gacagactgg accttgttga tgatagagta gatcttgtca
      961 ggatccttga gccacatagc accagcttcg ttcttcacga ttttgttgac agggcagccc
     1021 atgttgatat cgacgatatc ggtcttggtg ttttcttgga tgaattctgc tgcgcgtgct
     1081 aggctgtctt catcgctacc aaaaagttgg atagagacag ggttttcgcc ctcatcgata
     1141 tgaagcatgt gcagggtttt ttcgttgttg tattggattc ccttgtcaga gaccatttcc
     1201 attacaacga gtccagctcc gagctctttt gctatggtac gaaaggctga gttggtcacg
     1261 ccagccatag gcgctaaaac ggtacgattg ggaatctcaa tattgccaat cataaaaggt
     1321 gtattaagat ttgtcacgaa tgagttcctc caggtccttt tcatcaaagt tgtaagtagt
     1381 ttggcagaat tgacaagtga tttctgcacc gtggtcttcc tctttcattt cctgtaagtc
     1441 tgagcttgga aggctggcaa gagcgttcat aaagcgttca tggctacagt cacattggaa
     1501 acggatttct tcttcagaaa gacgcttgta ggcttcgtcc ccgtagatag ccttgaggag
     1561 ggcttcgata tggtcgtcgc tttcgagaag agtagagata gctggcattt cttggatgcg
     1621 tttttcaaag cgagcaatct cttctttctt ggctcctggc aagacttgaa ctaggaaacc
     1681 acctgcaacc ttgaccttgt cttcctcgtc caaaaggaca ttgaggccga ccgctgaagg
     1741 cgtttgttgg ctttcagtaa ggtaaaaggc aaggtcttca ccgatttctc cagagatgag
     1801 gggagttata gagttgtaag gatttccagt accgtagtct gtgataacga ggaattgacc
     1861 atttccaaca aaaggtccga ctaggacttc accagtcgca gtctttttga tgtcaacacc
     1921 aggattttga acatagcctt tgacgttccc cttggtatca gcgacggtga taatagcacc
     1981 tagagagcta gatcccaaca ccttaactgt aagtttggta tttccttttt cattggctgc
     2041 gagaatctgg ctggcgataa gagttcgacc aagcgctaca gttgagctag cttgggtttg
     2101 atgtttttct tgagcagtgc ggacggtttc agtgctatca aggacaaaag cacgaaaggc
     2161 tccgctttct gatatagttt taataatttt atccatagct actattttag cataaaaatg
     2221 cccaaagggg gagccgtgtg tttactgatt ttcaggataa tggaccagga aatcagcatg
     2281 aaaataaaaa gagaaacaga ttattttagc atttgtaaga tttatgctat gcttaaggta
     2341 gaaaatgaaa gggataacaa atgtatttag gagatttgat ggagaaagcc gagtgtggtc
     2401 aattttcaat cctttccttt ctattacaag agtctcagac gaccgtcaag gctgtaatgg
     2461 aagaaacagg attttcaaaa gcaaccctaa ccaaatatgt caccctgctc aatgacaagg
     2521 ctttggatag tggcttagaa ctgactattc actcagaaga tgaaaatctg cgtctgtcta
     2581 tcggtgcagc taccaagggg agagatattc ggagcttgtt tttggagagt gctgttaaat
     2641 accagatttt ggtttatctt ctctaccacc aacagttttt agcccatcag ctggctcaag
     2701 aattagtgat tagcgaggct acgcttggtc gtcacttggc tggtttaaat cagattttgt
     2761 cagaatttga tttatccatc caaaatggac gttggcgagg tccagagcat cagattcgct
     2821 atttctattt ctgtcttttc cgaaaggtct ggtcgagtca ggaatgggaa ggtcacatgc
     2881 agaaaccaga gagaaaacag gagattgcca atttagagga aatctgcggt gcaagtttgt
     2941 ctgcggggca gaaattggac ttggttctct gggctcacat cagtcaacaa cgtcttcggg
     3001 tcaatgcttg tcagtttcaa gttatagaag agaaaatgcg agggtatttt gacaatatct
     3061 tctatcttcg tttgctgaga aaggttccgt ccttttttgc tgggcaacat attccactag
     3121 gagttgagga tggtgagatg atgatattct tctcttttct cctatctcat cgcattcttc
     3181 ctcttcatac tatggagtat attcttggtt ttggagggca gttggcagat ttactgacgc
     3241 aattgattca agaaatgaag aaggaggaac tattggggga ttatacagag gaccatgtca
     3301 cctatgaact cagtcagctt tgtgctcaag tctatctcta taagggctat attttacagg
     3361 atcgctacaa gtaccagtta gagaatcgtc atccatattt actgatggaa catgatttta
     3421 aagagacagc agaggagatt tttcatgctc tacctgcttt tcaacagggg acagatttag
     3481 ataagaagat tctctgggaa tggctccagt taatcgaata tatggctgaa aacggtggcc
     3541 agcatatgcg gattggtctg gatttgacat ctggttttct tgtcttttca aggatggcag
     3601 ccattttgaa acggtatttg gaatacaatc gttttattac cattgaagct tatgacccta
     3661 gtcggcatta tgatttgctg gttaccaata accctattca taagaaggaa cagacaccag
     3721 tctattattt aaaaaatgac ttggatatgg aagatttggc agggattcgt cagttattat
     3781 tcacttaaaa ggcttggtta atccaggtct tttttgtgaa attcacacaa tctcctcaca
     3841 tttttttaaa aattaaaaaa agttgataaa caagaaagcg ctttattttg tatactagta
     3901 agtgtaaaga ggaaacacct caagatcttt atcaggagga cagtacatgt cacaagaaaa
     3961 atacatcatg gccattgacc agggaactac aagttctcgt gccatcattt tcaacaaaaa
     4021 aggggaaaag gttagctcga gtcaaaaaga gtttacccag attttccctc aagcaggttg
     4081 ggttgagcac aatgccaatg aaatttggaa ctctgttcag tcagttattg cgggtgcttt
     4141 catcgaaagt ggtgtcaagc caaatcaaat cgaggcaatc gggattacca accaacgtga
     4201 aacaacggtt gtctgggata agaaaacagg acttcctatc tacaatgcta tcgtttggca
     4261 gtcacgccag acagcacctt tggctgagca actaaaaagc caaggttatg tggaaaaatt
     4321 ccatgaaaag actggtttga ttattgatgc ttacttctct gctaccaagg ttcgttggat
     4381 tttggatcat gtagaaggtg ctcaagagcg agcagaaaaa ggggaattgc tctttggtac
     4441 tatcgatact tggttggttt ggaaattgac tgacggtgcg gctcacgtga ctgactactc
     4501 aaatgcagct cgtaccatgc tttataacat taaagaactc aaatgggatg atgagatttt
     4561 ggaaatcctt aacattccga aggctatact tccagaagtt cgttctaact ccgaaatcta
     4621 cggcaagaca gctccattcc atttctacgg tggagaggtg ccaatctcag gtatggctgg
     4681 ggaccaacaa gcagccctct ttggacagtt ggcttttgag ccaggtatgg ttaagaatac
     4741 ttatggaaca ggctctttca tcatcatgaa tactggggaa gagatgcagt tgtctgaaaa
     4801 caacctcttg acaaccattg gttacggaat caacggtaag gtttattatg ccttggaagg
     4861 ttctatcttc atcgcaggaa gtgctattca gtggcttcgt gacggtcttc gcatggttga
     4921 aaattcacca gaatctgaaa aatacgctcg tgattctcac aacaacgatg aagtttatgt
     4981 cgttccagcc tttacaggtc taggcgctcc atactggaac caaaatgctc gtggttccgt
     5041 ctttggtttg actcgtggaa caagcaaaga agactttatc aaggcgactt tgcaatctat
     5101 tgcttatcaa gtgcgtgaca tcatcgacac catgcaaatg gatactcaga ccgccattca
     5161 agtactgaag gtggatggtg gtgcagccat gaacaacttc ctcatgcagt tccaggcgga
     5221 tattttaggc attgacattg cacgtgctaa aaacttggaa acaacagctc taggagcggc
     5281 cttcctagca ggtttgtcag tagggtactg gaaagacttg gacgagttga aactcttgaa
     5341 cgagacagga gaactctttg agccatctat gaacgaatct cgcaaggaac aactctacaa
     5401 gggctggaag aaggctgtga aagcaactca agtctttgcg gaaatcgatg actaatactc
     5461 aatgaaaatc aaagagcaaa ctaggaagct agccgcaagc tgtacttgag tacggtaagg
     5521 cgacgctgac gtggtttgaa gagattttcg aagagtataa tactggcaga ataaagcgat
     5581 ttatttagaa agtgtgtaaa tatggaattt tcaaagaaaa cacgtgaatt gtcaattaaa
     5641 aaaatgcagg aacgcaccct ggacctcttg attatcggtg gaggaatcac aggagctggt
     5701 gtagccttgc aggcggcagc tagcggtctt gagactggtt tgattgaaat gcaagacttt
     5761 gcagaaggaa catctagtcg ttcaacaaaa ttggttcacg gaggtcttcg ctacctcaaa
     5821 caattcgacg tagaggtggt ctcagatacg gtttctgaac gtgcagtggt tcaacaaatc
     5881 gctccacaca ttccaaaacc agatccaatg ctcttaccag tttacgatga agatggagca
     5941 acctttagcc tcttccgtct taaagtagcc atggacttgt acgacctttt agcaggtgtg
     6001 agcaacacac caactgcgaa caaggttttg agcaaggatc aagtcttgga acgccagcca
     6061 aacttgaaga aggaaggctt ggtaggaggt ggagtgtatc ttgacttccg taacaacgat
     6121 gcgcgtctcg tgattgaaaa catcaaacgt gccaaccaag acggtgccct cattgccaac
     6181 cacgtgaagg cagaaggctt cctctttgac gaaagtggca agattacagg tgttgtagct
     6241 cgtgatctct tgacagacca agtatttgaa atcaaggccc gtctggttat taatacaaca
     6301 ggtccttgga gtgataaagt acgtaatttg tctaataagg gaacgcaatt ctcacaaatg
     6361 cgcccaacta agggagttca cttggtagtg gattcaagca aaatcaaggt ttcacagcca
     6421 gtttactttg acacaggttt gggtgacggt cgtatggtct ttgttctccc acgtgaaaac
     6481 aagacttact ttggtacaac tgatacagac tacacaggtg atttggagca tccaaaagta
     6541 actcaagaag atgtagatta tctacttggc attgtcaaca accgctttcc agaatccaac
     6601 atcaccattg atgatatcga aagcagctgg gcaggtcttc gtccattgat tgcagggaac
     6661 agtgcctctg actataatgg tggaaataac ggtaccatca gtgatgaaag ctttgacaac
     6721 ttgattgcga ctgttgaatc ttatctctcc aaagaaaaaa cacgtgaaga tgttgagtct
     6781 gctgtcagca agcttgaaag tagcacatct gagaaatatt tggatccatc tgcagtttct
     6841 cgtgggtcta gcttggaccg tgatgacaat ggtctcttga ctcttgctgg tggtaaaatc
     6901 acagactacc gtaagatggc tgaaggagct atggagcgcg tggttgacat cctcaaagca
     6961 gaatttgacc gtagctttaa attgatcaat tctaaaactt accctgtttc aggtggagaa
     7021 ttgaacccag caaatgtgga ttcagaaatc gaagcctttg cgcaacttgg agtttcacgt
     7081 ggtttggata gcaaggaagc tcattaccta gcaaatcttt acggttcaaa tgcaccgaag
     7141 gtctttgcac ttgctcacag cttggaacaa gcgccaggtc ttagtttggc agacaccttg
     7201 tcccttcact atgcaatgcg caatgagttg actcttagcc cagttgactt ccttcttcgt
     7261 cgtaccaatc acatgctctt tatgcgtgat agcttggata gtatcgttga gccagttttg
     7321 gatgaaatgg gacgattcta tgactggaca gaagaagaaa aagcaactta ccgtgctgat
     7381 gtcgaagcag ctctcgctaa caacgattta gcagaattaa aaaattaaga aaaaataaaa
     7441 gaggtggagg gcagcattcc ttgtcgcccg tcccttcttt ttaatggaga cagaaagatg
     7501 atgaatgaat tatttggaga atttctaggg actttaattc tgattcttct aggaaatggt
     7561 gttgttgcag gtgtggttct tcctaaaacc aagagcaata gctcaggttg gattgtgatt
     7621 actatgggtt gggggattgc agttgcggtt gcagtctttg tatctggcaa gctcagtcca
     7681 gctcatttaa acccagctgt gaccatcggt gtggccttaa aaggtggttt gccttgggct
     7741 tccgttttgc cttatatctt agcccagttc gcaggggcca tgctgggtca gattttggtt
     7801 tggttgcaat tcaaacctca ctatgaggca gaagaaaatg caggcaatat cctggcaacc
     7861 ttcagtactg gaccagccat caaggatact gtatcaaact tgattagcga aatccttgga
     7921 acctttgttt tggtgttgac aatctttgct ttgggtcttt acgattttca ggcaggtatc
     7981 ggaacctttg cagtgggaac tttgattgtc ggtatcggtc tatcactagg tgggacaaca
     8041 ggttatgcct tgaacccagc tcgtgacctt ggacctcgta tcatgcacag catcttgcca
     8101 attccaaaca agggagacgg agactggtct tacgcttgga ttcctgttgt aggccctgtt
     8161 atcggagcag ccttggcagt gcttgtattc tcacttttct agtttatact cttcgaaaat
     8221 caaattcaaa ccacgtcagc gtcgccttac cgtactcaag tacagcttgc ggctagcttc
     8281 ctagtttgct ctttgatttt cattgagtat tagaaaacaa ttatgttgat agagcttggg
     8341 caagagccca atttcagcaa aaaatgaagt aaatcttctc ataataaaac gcatcatatc
     8401 aagcacgaaa attccacgag gtcaactaca gtcagaaagc tgaacaacaa gccaaaacgc
     8461 ccaaaaaagg cggcaaaaag caagcacctg caagcaacgt gccgaaatgg tcaaatcctg
     8521 attatgtcaa cgaattagac ccaaaaatcg ttgatatgct agtagaattt cacaagtcac
     8581 aaggcacttt ggaaactccc gaggcgcaag cagaaatcgc ccaaaaacgt gaagaaatcg
     8641 agcaaaggag agctgagctt gaggataaaa aacaagagct tttgaaccgc ttgaacaaat
     8701 agagtttcgc aagtattatg cttacaaatt acttgagcaa ttaactaaaa tataaaccct
     8761 gcctttatat ctaggcaggg tttatatttt agaaattcac gtaggttgtt acggttttta
     8821 catacccagt atagtttgag tttctatagt attcagtgat aaacttccat tttctttgag
     8881 caacatggat ataagtactt gttatgtagt atggatatgg gctttgtgaa tccaagtaag
     8941 actgataagc ttgtatacca aaatatgctc caccaattat tgcaccccat ggacccccca
     9001 ataaagcacc tatcctacca atcatataac tgattccagc accagtcatg aagttagcga
     9061 atgtgttagc ttgtttattc ccatgtattg tgttgacgta atttcaaaca ttaggatcgt
     9121 atgatctaaa agatatattt aggtcgattt cattcttttg ataagccata taaaatgccc
     9181 cattgatata gacgccgtca gcacgtcgtt caatagtgtc tacacttcca tctggattga
     9241 caacctcaag aacttcatcg cttaaaatat ttacttgcgt atctccgaac cgcactgatg
     9301 agccattctc aaactgagcc tcaccagata caactttaga gtttgccgat aagctatcat
     9361 cagcaaaaac aacaagcgac ggggaaatgc tagacataca gaaaacagac ataactagca
     9421 aacacatgca tttaaacatc ttagacataa cggaaactct tttgtatttt tgattttttt
     9481 caacttttat tatacaataa aaccaaataa aaagaaagcg gtaacaatat gcttaatgcg
     9541 aaaatttttt atatattttt atgtttgatc gttatcgaaa ctacaggctt gttgttgttg
     9601 aaaagaggtc tcgaaatggg ttatttagac acagaagcta ttatcctcgc agttttttca
     9661 tttgcttttt acaacctatg ttcattcgct tgggtctgct ctacaataaa aaacaataaa
     9721 aaataaatag acgtattttc aaaaaaaaaa aaaatgcata tttatcttag caaaatgacg
     9781 atttaaatcg tcgttttttt gtagtacgac gggcatgtcg tatatctgag gtgtaagtcc
     9841 tcggtgggca cctgctaccg gtgaacccaa tagcgattcc caagcctgac tatcgtgagg
     9901 tagcagggag aggaagggat agcgaaatcg tggctctacg aacaggaacg tgatagtaag
     9961 gcgtatatag cggataagga ggcttcaaac tctaaagtcc aaaaaggtag tcgtaaccta
    10021 tatgtgtaaa tcacgagagt aattgaattc ggactaaggt ttgtgtgaaa aagataaatc
    10081 tttctagagt ctaaagactc tgcgtcagat ttcctatttt cactgtaacc ttttaacgtc
    10141 ctcatatctt gtataaacga ggaaagatgt acgacttatc ccgtgaggtt tcatgagcgc
    10201 tgaaagcgta gtaacaacga atcatgagaa gtcagccgag cccatagtag tgaggaaact
    10261 tctgtagtgg aagtggagcg acggggtgaa tactcaaaca gtctggggag agactgtttg
    10321 aggtctgtcg ctagaaagag aaaacgacag atcgaagtaa tcctacttca cttgtgtctg
    10381 taaaatgagt ggtctgatag aactggactt tgacacgtaa tgactagatg aaggttcacc
    10441 aatataagat gtccctcagg caccaaaaca agaaaggaat aggcacatgt caaaactgct
    10501 agataagata ttatcacgcg aaaatatgct ggaagcctac aatcaagtaa aatccaataa
    10561 aggctcagct gggattgatg gaatgactat cgaagagatg gataattatc tcagacaaaa
    10621 ctggcgcttg actaaggaac tgataaaaca gagaaaatat aagcctcaac cagttcttaa
    10681 agttgagata cctaaaccag acggaggcat ccgtcaacta ggaattccaa cagttatgga
    10741 tagaatgatt caacaggcca ttgtccaagt catgagcccc atttgtgaac cccatttctc
    10801 agatacgagt tatggtttca gaccaaatag gtcatgtgaa aaagccatca tgaagctctt
    10861 agaatactta aatgacggct atgagtggat agtggatata gacctagaga aatttttcga
    10921 tacagttcct caagatagat tgatgtcctt agtacataac attatcgaag acggagatac
    10981 ggaatccttg attcgtaagt atcttcattc aggtgttatc attaatggtc aacgttataa
    11041 aacactagtt ggtacaccac agggaggaaa tttatctcct ctcttatcca atatcatgct
    11101 taatgaattg gacaaggaat tagaaaagag gggacttcga tttgtgcgct acgcagatga
    11161 ttgtgtgatt acggtcggaa gcgaggcagc ctctaagcgt gtgatgtatt cagtcagtcg
    11221 ttttattgag aaacggctag gtttgaaagt aaacatgacc aagactaaga ttaccagacc
    11281 aagagagttg aaatatctag gttttgggtt ctggaaatca tcagatggtt ggaaaagccg
    11341 tccacatcaa gatagtgttc ggagatttaa gtttaaattg aagaaactaa cacagaggaa
    11401 atggagtata gacctaacaa gacgtattga gcaactgaat ttgtc
//
LOCUS       DAVBNN010000059        11410 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBNN010000059 DAVBNN010000000
VERSION     DAVBNN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.059"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ847_001725"
     CDS             complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ847_001725"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3051028.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2224..3483)
                     /locus_tag="VQ847_001726"
     CDS             complement(2224..3483)
                     /locus_tag="VQ847_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3051029.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3485..4186)
                     /locus_tag="VQ847_001727"
     CDS             complement(3485..4186)
                     /locus_tag="VQ847_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3051030.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4170..5369)
                     /locus_tag="VQ847_001728"
     CDS             complement(4170..5369)
                     /locus_tag="VQ847_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3051031.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5634..6980
                     /gene="gor"
                     /locus_tag="VQ847_001729"
     CDS             5634..6980
                     /gene="gor"
                     /locus_tag="VQ847_001729"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3051032.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7176..7712
                     /locus_tag="VQ847_001730"
     CDS             7176..7712
                     /locus_tag="VQ847_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3051033.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(7918..8133)
                     /locus_tag="VQ847_001731"
     CDS             complement(7918..8133)
                     /locus_tag="VQ847_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3051034.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8231..8551
                     /locus_tag="VQ847_001732"
     CDS             8231..8551
                     /locus_tag="VQ847_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051035.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8582..8920)
                     /locus_tag="VQ847_001733"
     CDS             complement(8582..8920)
                     /locus_tag="VQ847_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051036.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ847_001734"
     CDS             complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ847_001734"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3051037.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ847_001735"
     CDS             complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ847_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3051038.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10190..10978)
                     /locus_tag="VQ847_001736"
     CDS             complement(10190..10978)
                     /locus_tag="VQ847_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3051039.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11082..11325)
                     /locus_tag="VQ847_001737"
                     /pseudo
     CDS             complement(11082..11325)
                     /locus_tag="VQ847_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3274 a         2508 c         2077 g         3551 t
ORIGIN      
        1 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa tcacacttcc
      121 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgatag
      181 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
      241 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
      301 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
      361 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
      421 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
      481 gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt cttccatatt
      541 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
      601 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
      661 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
      721 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
      781 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
      841 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt gttctgcaac
      901 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
      961 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
     1021 ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
     1081 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
     1141 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
     1201 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
     1261 gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc cattccagaa
     1321 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
     1381 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
     1441 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
     1501 ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
     1561 acggtcttgg tatttgctaa ggcgaagaaa gtatgattct tcagaaaccc attcaacctc
     1621 atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
     1681 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
     1741 caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa ctttttcatg
     1801 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
     1861 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
     1921 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
     1981 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
     2041 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
     2101 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
     2161 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
     2221 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
     2281 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
     2341 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
     2401 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
     2461 aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac gaagaccaat
     2521 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
     2581 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
     2641 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
     2701 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
     2761 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
     2821 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
     2881 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
     2941 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
     3001 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
     3061 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
     3121 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
     3181 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
     3241 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
     3301 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
     3361 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
     3421 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
     3481 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
     3541 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
     3601 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
     3661 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
     3721 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
     3781 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
     3841 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
     3901 agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt tgtttttcac
     3961 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
     4021 tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg atggctacaa
     4081 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
     4141 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
     4201 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
     4261 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
     4321 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
     4381 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
     4441 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
     4501 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
     4561 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
     4621 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
     4681 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
     4741 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
     4801 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
     4861 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
     4921 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
     4981 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
     5041 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
     5101 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
     5161 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
     5221 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
     5281 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
     5341 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
     5401 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag caatcgttcg
     5461 gaatttttct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
     5521 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
     5581 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
     5641 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
     5701 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
     5761 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct gagactttcc
     5821 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
     5881 tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat agtagtttta
     5941 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
     6001 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
     6061 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
     6121 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
     6181 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
     6241 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga ataaacttgc
     6301 cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc attaccattc
     6361 atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
     6421 caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa cgtggcttta
     6481 tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
     6541 caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta tcagaacgtc
     6601 tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact gttgtctttt
     6661 cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa gaatacggtc
     6721 aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct tgcacttgca
     6781 accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa gttgtcggac
     6841 ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt gctatcaaaa
     6901 tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact tcatctgaag
     6961 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
     7021 tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga aaatcggctg
     7081 ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata
     7141 atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta
     7201 tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac
     7261 ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga
     7321 gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct
     7381 ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt
     7441 tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta
     7501 agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct
     7561 tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt cttcccttta
     7621 tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac
     7681 gccttaaaaa tcaggcttac tttactaact aaaaaaggat atcgagttat catgactcaa
     7741 tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactagaaa
     7801 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
     7861 taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg aagagtatta
     7921 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
     7981 gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag gggcaccatt
     8041 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
     8101 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
     8161 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaagaag
     8221 ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg attttttaaa
     8281 tggatatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
     8341 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
     8401 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
     8461 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
     8521 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
     8581 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
     8641 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg taacctgcgc
     8701 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
     8761 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
     8821 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
     8881 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
     8941 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
     9001 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
     9061 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
     9121 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
     9181 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
     9241 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
     9301 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
     9361 caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga gaataacgcg
     9421 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
     9481 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
     9541 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
     9601 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
     9661 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
     9721 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
     9781 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
     9841 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
     9901 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
     9961 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    10021 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    10081 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    10141 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    10201 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    10261 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    10321 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    10381 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    10441 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    10501 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    10561 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    10621 ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    10681 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    10741 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    10801 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    10861 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    10921 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    10981 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    11041 ttccaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    11101 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    11161 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatca
    11221 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    11281 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    11341 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    11401 ttttatagta
//
LOCUS       DAVBNN010000060        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBNN010000060 DAVBNN010000000
VERSION     DAVBNN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.060"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ847_001738"
     CDS             <1..116
                     /locus_tag="VQ847_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3051040.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ847_001739"
     CDS             140..1063
                     /locus_tag="VQ847_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3051041.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ847_001740"
     CDS             1145..2773
                     /locus_tag="VQ847_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3051042.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ847_001741"
     CDS             2882..3832
                     /locus_tag="VQ847_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3051043.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ847_001742"
     CDS             3849..4700
                     /locus_tag="VQ847_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3051044.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ847_001743"
     CDS             4713..6695
                     /locus_tag="VQ847_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3051045.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ847_001744"
     CDS             6705..8114
                     /locus_tag="VQ847_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051046.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ847_001745"
     CDS             8119..8607
                     /locus_tag="VQ847_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3051047.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ847_001746"
     CDS             8895..9302
                     /locus_tag="VQ847_001746"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3051048.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ847_001747"
     CDS             9334..10251
                     /locus_tag="VQ847_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3051049.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ847_001748"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ847_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ847_001749"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ847_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3051050.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3693 a         1665 c         2115 g         3612 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta tagaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggtattac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBNN010000061        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBNN010000061 DAVBNN010000000
VERSION     DAVBNN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.061"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ847_001750"
     CDS             complement(128..1759)
                     /locus_tag="VQ847_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3051051.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ847_001751"
     CDS             2052..6992
                     /locus_tag="VQ847_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3051052.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ847_001752"
     CDS             7082..8278
                     /locus_tag="VQ847_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3051053.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ847_001753"
     CDS             8414..8941
                     /locus_tag="VQ847_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3051054.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ847_001754"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ847_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3051055.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ847_001755"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ847_001755"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3051056.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ847_001756"
     CDS             complement(10847..10966)
                     /locus_tag="VQ847_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3051057.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2037 c         2414 g         3044 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caactcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBNN010000062        10939 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBNN010000062 DAVBNN010000000
VERSION     DAVBNN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.062"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(65..1201)
                     /gene="dnaJ"
                     /locus_tag="VQ847_001757"
     CDS             complement(65..1201)
                     /gene="dnaJ"
                     /locus_tag="VQ847_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3051058.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1406..1759)
                     /locus_tag="VQ847_001758"
     CDS             complement(1406..1759)
                     /locus_tag="VQ847_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051059.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(1772..3595)
                     /gene="dnaK"
                     /locus_tag="VQ847_001759"
     CDS             complement(1772..3595)
                     /gene="dnaK"
                     /locus_tag="VQ847_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3051060.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4075..4599)
                     /gene="grpE"
                     /locus_tag="VQ847_001760"
     CDS             complement(4075..4599)
                     /gene="grpE"
                     /locus_tag="VQ847_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3051061.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4626..5660)
                     /gene="hrcA"
                     /locus_tag="VQ847_001761"
     CDS             complement(4626..5660)
                     /gene="hrcA"
                     /locus_tag="VQ847_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3051062.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(5824..6333)
                     /locus_tag="VQ847_001762"
     CDS             complement(5824..6333)
                     /locus_tag="VQ847_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3051063.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            6941..7241
                     /locus_tag="VQ847_001763"
                     /pseudo
     CDS             6941..7241
                     /locus_tag="VQ847_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7436..9274
                     /locus_tag="VQ847_001764"
     CDS             7436..9274
                     /locus_tag="VQ847_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3051064.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9287..10750
                     /locus_tag="VQ847_001765"
     CDS             9287..10750
                     /locus_tag="VQ847_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3051065.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            10750..>10939
                     /locus_tag="VQ847_001766"
     CDS             10750..>10939
                     /locus_tag="VQ847_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3051066.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3326 a         2143 c         2146 g         3324 t
ORIGIN      
        1 gatacgactc acatatatac ggcaaggcaa cgctgacgtg gtttgaagag attttcgaag
       61 agtattattc tccatcaaag gcatctttta tatggtcaaa gaagcctttt ttctttggat
      121 ttactttcaa gtcaccagca gtcgcgaatt ctttcaaggc tactttttgg cggtcgttca
      181 agcctgtcgg tgttacgaca ttaacagtaa cgtattggtc accaactgca ccgccacgaa
      241 ggctcggtgc ccccttacta cgtaggcgga atttcttacc agtctgagtt ccctctggaa
      301 taaccaattc aacatcaccg tgaacagttg gaatatctac tgtatcacca agagccgctt
      361 ggacaaagtt gaggttgaga ttgtagaaga tagtcgttcc ttcacgttca aacttgtcgc
      421 tagcttctac agaaactact acatacaagt caccataagg tccaccgtta aagcctgctt
      481 caccttgacc agcgaggcga atttgttgac ctgtttccac accagcaggg attttcacat
      541 gtacgctatg agcttgtttc tcatgacctg ttccatgaca ggttgtacat ggatatttga
      601 tttcttttcc tcgaccgtga cagacatcac aggttacttg gcgacgcatc ataccaagag
      661 gagtctgcgt atcgacgtta atgacaccag cgccatgaca gcgtccacaa gtgactggac
      721 ttgtccctgg cttagcacca gagccattac atgtacgaca gccagcttca cgatgatact
      781 taacttcctt ctcagttccg aagatagctt cttcaaatgt caaattgaca cgatactgga
      841 gatcatctcc ttggcgagga gcgtttggat tgcgcgaaga accgcctccg ccgaagaaac
      901 ttgagaaaat atcctcaaaa ccaccgaagc cacctgcccc attgaaacca ccgaaaccac
      961 cagctccacc aaaaccacca ttggcgcctg cagcaccata ctggtcatag gcagcacgtt
     1021 tttggtcgtc actcaaagtc tcataggctt cttgaacttc cttgtacttg tcctcagcac
     1081 caggctcctt gttgatatct gggtgatatt ttttggaaag cttacgataa gcctttttga
     1141 tctcgtctgc cgaagcgttt tttgacaccc ccagacgatc ataaaattca gtattgttca
     1201 tacaagatac caagaccgta aaattcgact gaaaaatagg aaatctgacg ctggagcgac
     1261 gctcctagac agatttctct tttttccgag aatttaggtc gggttcaatt cctttctttt
     1321 atattgatga gataatactc cagccactcg gccctatccc tttttaccga aaaacagagg
     1381 ctgggttgca acctctgtgg ttagattatt catttgaaat aaaaatggtt gtattatctc
     1441 tagtagtaat cttcaaagac cttttagcta aatcaaactc aaatttatta tagtgtgggt
     1501 cttgtgtttt atataggtgt aactcctgac atatatgatc cgaaaagtaa atcataacat
     1561 ctttaaacac agaagtgtag tcatatttac tcttaccaac agctacttct gtaaattctt
     1621 tataaatgac atttccattt ctttccacag tcaccagcat ttctgttgga ttataatcca
     1681 aattaaataa ttcttcaaaa aactttatct tttcatgata atctgcaatg tcagaaagat
     1741 tatttttatt aacactcata acactagccc cttatttttc cgtaaactct ccgtctacga
     1801 cgtcatcgcc tgcgtttcct gttgcttgtg cgccttctgc tccttcttga gcttgttgcg
     1861 ctgctgcggc ttgttcgtag agtttaacag caagtccttg agctttttcg ttcaatgctt
     1921 caagtttcgc tttcatgtcg tccaagttgt tgtcttcttg agctttctta aggtcatcaa
     1981 gggcagcttg ggcagcgtca cgttctgcgt cgaagccttt accttcagtt tccttgattg
     2041 tcttttcagt cgcaaagatt gcttggtcta cttcattacg aaggtctact tcttctttac
     2101 gtttcttatc ggcttcagcg tttgcttctg catctttcat catgcggtcg atttcttcgt
     2161 cagtcaaacc tgagttcgat tggatgacaa tagtttgttc tttttgagtt ccaaggtctt
     2221 tggccttaac agacacgata ccgttcttgt cgatgtcaaa tgttacttcg atttgaggaa
     2281 ttccacgagg tgcagctggg atatcagtca attggaagcg tccaagagtc ttgttatctg
     2341 ctgccattgg gcgttcacct tgaagaacgt ggatatcaac ggctggttgg ttgtctgctg
     2401 ctgttgagaa gacttgtgat ttagatgttg ggattgtagt gttgcgatcg ataagttttg
     2461 taaatactcc acccattgtt tcgataccaa gtgacaatgg cgttacatca agaaggacaa
     2521 cgtccttgac atcaccagta atcacaccac cttggatagc cgcacccata gcaactactt
     2581 catcagggtt tactgatttg tttggttctt taccagtttc agctttaaca gcttcaacaa
     2641 cggcagggat acgagttgaa ccaccaacaa ggataacttc gtcgatttct gacaagctca
     2701 aacctgcatc tgaaagggct tgacgaactg gaacttttgt acgttcaaca aggtcacgag
     2761 tcaaatcatc aaatttcgca cgagtcaaag tcatttccaa gtgaagaggt ccagcctcac
     2821 ctgcagtgat aaatggcaag ctgatttgtg ttgaagttac accagaaagg tctttcttcg
     2881 ctttttcagc cgcatctttc aaacgttgca ttgccatctt gtcagtagac aagtcgatac
     2941 cgttttcttt cttgaattct gctaccaagt ggtcaatgat tttttggtca aagtcgtcac
     3001 caccaagttt gttgtcccct gcagttgaca atacgtcgaa gacaccgtca cccaattcaa
     3061 ggatagagac gtcgaatgta ccaccaccaa ggtcaaatac caagattttt tcttctttat
     3121 cagtcttgtc caaaccataa gcaagagctg ctgcagttgg ttcgttaaca atacgttcta
     3181 cttcaagacc agcaatttta ccagcgtctt ttgttgcttg acgttgagcg tcgttgaagt
     3241 aagccggaac tgtgataaca gctttggtta ctttctcacc aaggtagtct tcagcgtagc
     3301 ctttcaagta ttgaaggatc atagctgaga tttcttgtgg agtgtattct tttccatttg
     3361 cagaaacttt ttcagaagtt cccatcttag atttgataga gataactgta tctgggtttg
     3421 tgactgcttg acgttttgca gcatcaccaa cgatgatttc tccgtttttg aatgagacta
     3481 cagatggagt tgtgcggttt ccttctgggt ttgcgatgat tttgctttca gttccttcaa
     3541 gaactgcaac tgctgagttt gttgtaccta agtcaatacc gataatttta gacatgtgtt
     3601 tttctccttg ttagttaatt ttctattttt ctttttgata ctcttcttaa gtggcgacgc
     3661 cgtcagagct tgacttcgtc aatctctttg actaaacttt gagcctaagg tctcaaaatt
     3721 tgcgcaaata gcgccacggc gaagagtatc gtgtttggtt cgcttcgctc actattacaa
     3781 agccaaacat attttatctt tcttcatagt ttattgtcgt ttcggacaag ttttctatta
     3841 tgtaaattgc gacacgaaga gtcgaaatcg attttatttc gacgacgagt tagtaaggaa
     3901 gctaggcaaa cgccatagcg attgccgttt tctgacgagt tgctttagct accgtcagaa
     3961 ttgccgaatc gaacacgccc taagctctga gtaaaaaaga tagattttct tgtgttcatc
     4021 gaacacttcg ttaatctcct atttttactg cgagcttttt acgggctttg tatcttagtt
     4081 atacaccact accattgctg ggcgtaggat gcggtcatgg agtttgtagc ctttttgaaa
     4141 gacttgagcg atggtatcta ctgggtgttc atcgtctgct gggagagttt ggatggccat
     4201 atggtagtta tggtcaaatt cgccatctgc tgcgatttct tcaattcctt cttctttcaa
     4261 agcgtgaatc aagctttctt gcaccatccc caagcccttc ttcacatcat ctgtcaaacc
     4321 ttcaactgca agtgcacgct caaggttgtc aagagatggt aagattgctt ttgccaagtc
     4381 ctggctacga taacgttgca agttttgacg ttcttcattg gcacggcgtt ggatattttg
     4441 catttctgca tgagcgcgaa gatatttgtt ttcgaactca tctgcacgtt catttgccaa
     4501 gtccaactca gacttttcag gagttgtttc ttcagctgtt tccacaactt cctcttcttg
     4561 aacttcttct acttcttcat tttttatatc ttgggccatg ttcgcctcct ttaatgattt
     4621 caatcttaat gtacttcgta atgattactg ctgaggtagc ggtaaaaatc tgtcaacttc
     4681 atggtcaaaa cacggttgac cacattgatt tgattgatta gctgttggta atccagatta
     4741 actggaccga taatggctag aattccaact ccccgataag gaatgaggaa cttactacta
     4801 atcaccgcta ggtcagctaa acaggactct tgaccgtctg caatacgaac attttgcatc
     4861 tgatcctcac gcaacccctc acgaatctcc aaggccacct tttgcggttg gtcaaagaac
     4921 tgataggctg ctagattggc aaaattcaag agattgacct tgcccgccat cacaatgttt
     4981 tcgttgaaca tttccttaaa gatgtgttca aagagatcga tgacattatc cgttgttgta
     5041 aagtaacgct ggataatctg cggaatctcc gtccgaatct tgtagtgaat atctaaaacg
     5101 gtgtgaccga ggaaacgttc ctgaatgatg ctcttcagtt tcagcaaatc ctcctgcaag
     5161 aagttccttg gaatcagaaa ctgactagta accgttcgcg actcgtctag ggtaaatacc
     5221 gccaaggctg tatgttgccc caaaacaacg atatcaaagg ctgtcaaacg ttgcctgctc
     5281 ggctcaacat ccagtgccac taccgtacag ccactcaggt ctgttagcaa gttagcagcc
     5341 tcttgcagaa tatcctccaa tttgaagaat tcctgatcaa aggctttgac aatctcatat
     5401 acctcatttt cagccagccg gtgaaaatcc agtgagtgtt tcacatagta ctgaaaacca
     5461 gcaacacttg gcatccgacc gcttgaagta tgagccttct caagcaaccc ttgtttttct
     5521 agttccgcca tgtcattacg aatggttgca ctgctagagt taatagactc ttgcaaggct
     5581 tttgatccga caggttcgtg cgttttggta aagatgtcaa taatcagatt taaaatatcc
     5641 tgctgacgct ctgtaaccat ctcatcactc ctctctgtct gatcaattag cactcaatgc
     5701 atccaagtgc taacttatga ttctattata cacccttaga agagaatgtc aagacaaaaa
     5761 ctcaaaaaat tagcactctt ttatcaagag tgctaaaaat caatctgaag acctagaacc
     5821 ttgctattca tctactcggt atttcctttt tagtctgaaa taaccatgaa ttagataaga
     5881 aatcagaaaa gcatataaaa caaaaataag aaagaaagac atagaaagat cctctctaaa
     5941 caaactcgta caaacaacaa gaccacctaa gaaagtagct gtacaggaac gaagtctaga
     6001 tcgcataact tcccatttga gccccttact catatagact tgatcctctg gaagtaaatc
     6061 agaagacgat ttacgaagaa tcgaacaaga acctgctcct atcaattccc aacctctatc
     6121 tctaaaatct tgcagttcat gcttatattt tttaagaaat ctagaatcat agatacggta
     6181 gatgacatcg tctggttgac attggtcaaa atagaacaaa ccaaaacgac tcgttctata
     6241 cctccaacct ttcaaatgca tctcatgtaa atattcttct ttcttgtcca aatcaacaat
     6301 ggtgaaaatc cgaaattcta ctctgctatt cattgtctta ccccaaaatt agaaaacatg
     6361 cctagcgtta tttattagat aattctttcc acttttgact caatctccaa aaaatataag
     6421 aaatctgaat cgcaaaaact atcaataaaa cccaatctat tatgaaaatc aaaaacactt
     6481 cccaactgaa agaactacct ccagtgacaa actttgagaa aaacggtagt agagctaaaa
     6541 agagaagcaa aataggaagc atccgcattg ttaaaatccg tttggcataa aaaaatcttt
     6601 atttaaacga aaatattatg gcaaaattta cgccagtttt tgaacggctg atgtagatat
     6661 tttatacttt caaaatgttt aaatgtgatt atttattttt gaaaaatagc tcaccagccc
     6721 gactgaaagt gcttatagaa tgataataag tcgcctgccg aaaacagcgg aaaatagcgg
     6781 tgttatgcgg agataatctg acgcgatgcg aaagtatatt gcatacttat tttcaacaat
     6841 ttagcagagt atttttataa gtgtgatata atagaagtat aatttgttct gatagtttat
     6901 tttatggaga agtagatttt tagaatgcgg agggttcaat atggttgagt ttataaagtc
     6961 taagaaagaa atgagtgagg aggatattaa agcaaatttc atcactcctg ctattgtatc
     7021 caaaggatgg aaaaatggtg agcatatcgc ttacgaagaa tacttcactg atggtcgaat
     7081 tgaggttaga ggagataagg ctcgtcgtaa agaaggaaaa aaatcagact attcactgta
     7141 ttaccaattt ggaactcgaa ttgcaattgt tgaggcaaag gataataaac acagcgttcg
     7201 agcaggatta caacaagcta ttgaatatgg agagatttta gatgttccat ttgtttattc
     7261 ttcaaatggt gatggcttta ttgaacacga ccgtatcacg agagaagaac gtgagctgga
     7321 gttagacgaa ttccctactc gtgaagaatt attttctcgt atgacgaagg aaaaaggatt
     7381 gacgtacgaa attacagaag ctatctaaac tccatactat acagacgcct tctcaatgaa
     7441 aacgccacgc tattatcagc aaatagctat caaccgtact attgaaacag ttgccagagg
     7501 acaaaaacga gtaatgtttg tgatggcaac aggaacgggg aaaacgttca tggcttttca
     7561 aattattcat cgccttcgaa aagctggttt ggctaaacga gttttattct tagcggatag
     7621 aaacatctta gtagaccaaa cgatggctga agactttaag ccattcgaaa aggtaatgac
     7681 gaaaattaca ccaaaacttt tgactgctcc tgaaaaatta aattcttttg aaatttatct
     7741 agggctttat cagcaactaa ctggtgaaga tggaactgaa acacattatc aaaaatttga
     7801 caaagacttc tttgatttaa tcgtaattga tgaagcgcac cgtggttcag ctaaggaaaa
     7861 cagtaactgg cgtaagataa ttgattattt cagttctgcg acacagattg ggatgaccgc
     7921 tactcctaaa gaaaccaaga atgcttccaa tacggaatac tttggtgagc caatctatac
     7981 ttatagttta aaacagggaa tcgaggatgg ttttttggct ccatatcgtg ttatgagggt
     8041 taatttagat gtggatgtgg atggttatcg tccagaaact ggaaaagttg atactaacgg
     8101 acaattaata gaagataggt actacggcag gaaagatttt gataaaacca ttgtcattga
     8161 tgatagaacg caaagagttg ccaagtttgt ttctgattat atgaagcaaa gcaatgcacg
     8221 atttgataaa acaattgttt tttgtgttga tattgaccat gccgagcgaa tgcgtgctgc
     8281 acttgtaaaa gagaatctag acttagtcca agaagactat cgttatgtca tgcaagtaac
     8341 tggtgacaac gctgaaggaa aagctcaact ggataacttt atggatgtca attctaattt
     8401 tcccgctatt gtaacaacgt ctaaattatt aacgacagga gttaatgcta aaacatgtcg
     8461 tttgattgtt ttagactcta atatccaatc catgactgaa tttaaacaaa ttattggtcg
     8521 tggcacacgt ctttatcctc aaaaggggaa agaatttttt acgattattg attttcgaaa
     8581 tgttaccaat ttgtttgctg accctgattt tgatggtgag ccagtgaagg tgctggaaac
     8641 aggtgcgaaa acagtcagtg gttccacgcc cggtttcgta gatgaggaag gtgacccagt
     8701 agaaaaatat atcgttacag acaagcaggt taccattctt aattctactg ttcaagtatt
     8761 ggatgaaaac gggaaactga ttaccgaaag cctgaccgac tacactcgga agaatatctt
     8821 aggtagctac gccactttga acgattttat cacagtttgg catacggcgg ataaaaagaa
     8881 gcttatctta gacgaacttt ataaaaaagg agtttatcta gatgctattc gagagtcgga
     8941 gggaatatca gaacaagaaa tcgatgattt tgatttactc ctaaaacttg cctatggtca
     9001 aaaagaatta accaaaacgg aacgtatcaa taaactcaaa caaagcggat atttatataa
     9061 atatagtgag gaagcgcgtg ctgttttgga aattttactg aacaaataca tggataaagg
     9121 tattggagaa ctcgaaagca ttgaaacatt aaaacttcca gaatttcaga tatatggtgg
     9181 aaccttcaaa atcatcaata cttattttgg agataaaaaa cgatatttac aagcaattaa
     9241 agaattggag caagagctat ttacagtagc ttaatgaaag gaaagtatgt caattacatc
     9301 atttgtaaaa agaattcaag atatcactcg aaacgatgct ggtgttaatg gtgatgctca
     9361 acgtattgag caaatgtctt ggttattatt cttaaaaatt tatgatagcc gtgaaatggt
     9421 ttgggaatta gaagaagacg agtatgagtc aattatccca gaggaattaa aatggcgaaa
     9481 ttgggctcat gctcaaaatg gggaacgggt attgacaggc gatgaattac ttgattttgt
     9541 caataacaag ttattcaaag agttgaaaga gcttgaaata acttcaaata tgcctattcg
     9601 aaaaacgatt gttaaatcag cttttgaaga tgcgaacaac tatatgaaaa atggcgtctt
     9661 gttacgccaa gtcatcaatg ttattgatga agttgatttc aatagccctg aagatcgtca
     9721 ttcgtttaat gatatttacg aaaaaattct taaagatatt caaaatgctg ggaactcagg
     9781 agaattttat acgccacgtg cagcgactga ttttattgcc gaagttcttg acccaaaact
     9841 tggagaatca atggcagacc ttgcttgcgg aacaggaggc ttcttgactt cgactctgaa
     9901 ccgtttaagt agtcaacgta aaactagtga agataccaaa aaatataata cagctgtttt
     9961 tggtattgaa aagaaagcat ttcctcatct tttagcagtt acaaatctgt ttcttcacga
    10021 aattgatgac cctaaaattg ttcatggaaa tactttggag aaaaatgttc gtgaatatac
    10081 ggatgatgaa aaatttgaca ttattatgat gaatccacct tttggagggt cagaattaga
    10141 aacaataaaa aataactttc cagcagaatt acggagttct gaaacagctg atttatttat
    10201 ggctgtcatt atgtatcgtt tgaaagaaaa tggtcgtgtt ggagttattt tacctgatgg
    10261 ttttctattt ggtgaaggtg taaaaactcg cttgaaacaa aaactggtag atgagttcaa
    10321 cttgcatacg attattaggt tgcctcatag tgtctttgca ccgtatacag gaatccatac
    10381 gaacattctt ttctttgata aaacaaagaa aacagaagaa acttggtttt atcgtttaga
    10441 tatgccagat ggttataaaa atttctcgaa aactaagccg atgaagtcag aacacttcaa
    10501 tcctgttcgt gactggtggg aaaatcgtga agagattctg gaaggtaagt tctacaaatc
    10561 taaatcattt acacctagtg aattggctga gttgaattat aatttagacc agtgtggttt
    10621 tccaaaagag gaagaggaaa tcttaaatcc ctttgagttg attcagaatt atcaagcgga
    10681 aagagcaact ttaaatcata agattgataa tgtattagct gatattttgc agttgttgga
    10741 ggacaaataa tgacaccaga acaacttaaa gcaagtattc tccaaagagc gatggaaggg
    10801 aaattagtgc cgcaaaatcc caatgacgaa cctgcaagtg aattattaaa gagaattaaa
    10861 gctgaaaaag aaaaacttat cagtgaagga aaaatcaaac gagataaaaa ggaaactgag
    10921 atatttcgtg gtgatgatg
//
LOCUS       DAVBNN010000063        10754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBNN010000063 DAVBNN010000000
VERSION     DAVBNN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.063"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ847_001767"
     CDS             complement(117..1541)
                     /locus_tag="VQ847_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3051067.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ847_001768"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ847_001768"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3051068.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ847_001769"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ847_001769"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3051069.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLLVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ847_001770"
     CDS             complement(6527..7705)
                     /locus_tag="VQ847_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3051070.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ847_001771"
     CDS             complement(7785..8648)
                     /locus_tag="VQ847_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3051071.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ847_001772"
     CDS             complement(8651..10552)
                     /locus_tag="VQ847_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3051072.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3221 a         2371 c         1915 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actaataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtac
//
LOCUS       DAVBNN010000064        10686 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBNN010000064 DAVBNN010000000
VERSION     DAVBNN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.064"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ847_001773"
     CDS             85..366
                     /locus_tag="VQ847_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3051073.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ847_001774"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ847_001774"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3051074.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1433..2937)
                     /locus_tag="VQ847_001775"
                     /pseudo
     CDS             complement(1433..2937)
                     /locus_tag="VQ847_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ847_001776"
     CDS             3042..3782
                     /locus_tag="VQ847_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3051075.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ847_001777"
     CDS             complement(3811..4266)
                     /locus_tag="VQ847_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3051076.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ847_001778"
     CDS             complement(4286..5461)
                     /locus_tag="VQ847_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3051077.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ847_001779"
     CDS             complement(5520..6365)
                     /locus_tag="VQ847_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3051078.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ847_001780"
     CDS             6490..7047
                     /locus_tag="VQ847_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3051079.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ847_001781"
     CDS             7066..7533
                     /locus_tag="VQ847_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3051080.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ847_001782"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ847_001782"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3051081.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ847_001783"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ847_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3051082.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ847_001784"
     CDS             9094..9342
                     /locus_tag="VQ847_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3051083.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ847_001785"
     CDS             9443..10603
                     /locus_tag="VQ847_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3051084.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
BASE COUNT         3384 a         2106 c         2278 g         2918 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggtcat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtc agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggttatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaact
//
LOCUS       DAVBNN010000065        10507 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBNN010000065 DAVBNN010000000
VERSION     DAVBNN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.065"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            166..378
                     /locus_tag="VQ847_001786"
                     /pseudo
     CDS             166..378
                     /locus_tag="VQ847_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            278..724
                     /locus_tag="VQ847_001787"
     CDS             278..724
                     /locus_tag="VQ847_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3051085.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(862..2166)
                     /gene="eno"
                     /locus_tag="VQ847_001788"
     CDS             complement(862..2166)
                     /gene="eno"
                     /locus_tag="VQ847_001788"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3051086.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2330..2776
                     /locus_tag="VQ847_001789"
     CDS             2330..2776
                     /locus_tag="VQ847_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3051087.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2773..3888)
                     /locus_tag="VQ847_001790"
     CDS             complement(2773..3888)
                     /locus_tag="VQ847_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET3051088.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4002..4226)
                     /locus_tag="VQ847_001791"
     CDS             complement(4002..4226)
                     /locus_tag="VQ847_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3051089.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4171..4542)
                     /locus_tag="VQ847_001792"
     CDS             complement(4171..4542)
                     /locus_tag="VQ847_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3051090.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4601..6034)
                     /gene="glgA"
                     /locus_tag="VQ847_001793"
     CDS             complement(4601..6034)
                     /gene="glgA"
                     /locus_tag="VQ847_001793"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3051091.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6031..7170)
                     /gene="glgD"
                     /locus_tag="VQ847_001794"
     CDS             complement(6031..7170)
                     /gene="glgD"
                     /locus_tag="VQ847_001794"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3051092.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7160..8302)
                     /locus_tag="VQ847_001795"
     CDS             complement(7160..8302)
                     /locus_tag="VQ847_001795"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3051093.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8292..10220)
                     /gene="glgB"
                     /locus_tag="VQ847_001796"
     CDS             complement(8292..10220)
                     /gene="glgB"
                     /locus_tag="VQ847_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3051094.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3200 a         2301 c         1847 g         3159 t
ORIGIN      
        1 acttttttga agcttggttt cagaaatttc tcttaccaac attaaccgca ccattggtta
       61 ttatattaaa acgaagtaag aataggacaa atcgatcagg acagtaaaat ctaattctaa
      121 caatgtttta gaagtagagg tgtactattc tagtttcaat ctactatatt aatggacaat
      181 gcaagattcc atagaatggg gaagctagaa ctcttgtgtg aagagtttgg gcataaactt
      241 ttacctcttc ctccctactc gcctgagtac aatcttattg agaaaacatg ggctcatatc
      301 aaaaagcacc tcaaaagggt attaccaagt tgcaatacct tttatgaggc tcttttgtct
      361 tgttcttgtt tcaattgact atataaattg tctaagcgaa acaaccgata agaattggca
      421 caaaagcgac cgtatttttg ttaccaatac aggaaaacca gttcatagtt ctatcttgag
      481 caagtctctc cagcgagcaa acgaacgcct taaaaaacca attcccaaac atctgtcccc
      541 tcacatcttc agacacacca ctattagcat cttatcagaa aataaaattc ctttaaaaac
      601 aatcacggac agggttggtc attccgactc tgaagtcact acttccatct acacccacgt
      661 cacaaagaac atgaaagatg aagcaatcaa tgtactggat aaagttatga aaaagatttt
      721 ttaaaaagtt ttgtcccttt tttgtcctct aaatacaaaa atagcccttc ggataaaatc
      781 cgaggggcta gaaacgttgt taaatcaacg gccgaacttt tgaatttcat ggttcgggat
      841 aaaatagttc actgaactat tttatttttt aaggttgtag aatgatttca atccacgata
      901 ttcagctact tcaccaagtt ggtcttcgat acgaagcaat tggttgtatt tagcgatgcg
      961 gtctgtacgt gaaagtgaac cagtcttgat ttgtcctgcg ttagttgcaa ctgcaatatc
     1021 agcgattgtt gaatcttcag tttcacctga acggtgtgat acaacagcag tgtaaccagc
     1081 ttctttagcc atttcgatag cttcaaaagt ttcagtaaga gtaccgattt ggttaacttt
     1141 gataaggatt gagttagcag caccttcttg gataccacgt gcaaggtagt cagtgtttgt
     1201 tacgaagaag tcgtcaccaa caagttgtac tttcttacca agacgttcag taagagcttt
     1261 ccaaccatcc cagtcgtttt catccatacc atcttcaata gtgatgattg ggtatttgtt
     1321 aaccaattct tcaaggtagt cgatttgttc tgcagatgta cgaacagcag caccttcacc
     1381 ttcaaattta gtgtagtcgt aaactttacg ttctttatcg tagaattctg atgaagcaca
     1441 gtcaaatccg ataaatacgt ctttacctgg tacatatcca gcagcttcaa tcgcagcaag
     1501 gatagtttca acaccatctt cagttccttc gaaacgagga gcgaatccac cttcgtcacc
     1561 tacggcagtt tccaaaccac gtgatttaag gattttctta agagcgtgga agatttcagc
     1621 accgtaacga agggcttctt taaatgttgg cgcaccaact ggcaagatca tgaactcttg
     1681 gaaagcgatt ggagcgtcag agtgagaacc accgttgatg atgttcatca ttggagttgg
     1741 aagaacttta gtgttgaatc caccaaggta gctgtaaagt gggatttcaa ggtagtcagc
     1801 agcagcacga gctacagcga tagacacacc gaggattgca ttcgcaccca atttaccttt
     1861 gttaggagta ccgtcaagtg cgatcatagc acggtcaata gcttgttgat cacgtacatc
     1921 gtagccaatg atagcttcag caatgatgtt gtttacgttg tcaacagctt tttgtgtacc
     1981 aagaccaccg taacgagatt tgtcaccgtc gcgaagttca actgcttcgt gttcaccagt
     2041 agaagctcct gatggaacca taccacgtcc gaaagcacct gattcagtgt aaacttctac
     2101 ttcaagtgtt gggttaccgc gtgagtctag gacttcgcga gcgtaaacat cagtaataat
     2161 tgacattttt tactctcctt atgagttaaa ttttttacac ctctataata ccttaaaacc
     2221 cctccttttt caagaaaaaa cgttatcttt gtgcaacttt tccttaactt tataaagtaa
     2281 tcgctttctt ttgtctgttt tattctaact tttatgatat actgttttca tgacagattt
     2341 atcaaaacaa ttacttgaaa aagctcatgg tgggttaaaa ataaatccgg atgagcaaag
     2401 acgctatctt ggtacttttg aggaaagagt tcttggatat gtagatattg acacagcaaa
     2461 tagccctcag ttagaaaaag gctttttatt tattttagaa aaccttcagg aaaaagcaga
     2521 gccactattt gtgaagattt caccaactat cgaatttgat aagcaagttt tctacttaaa
     2581 agaagcaaaa gaaactgata gtcaagccac catagtatct gaagagcata ttacttctcc
     2641 tttgggcctg gttattcata gcaatgcacc agttcaagta gaagaaaaag accttcgact
     2701 tgcttttcca aaactttggg aagttaaaaa ggaagaacca gccaaaacat ccttatggaa
     2761 gaaatggttt agctaaatct tgcacatatt taataagtgc ccaatattgg cagccgtgcg
     2821 ctccagatag agactggcat ttttcaaact atcttctaaa ggttcacttt tctccaaaat
     2881 agaaaagaca gcttggatat tttcaaatgg taggggaggt aaatcttcag caagactacc
     2941 gcaaatagca ataacaggaa ctccaacagg ggttcttttt gcaacaccta taggcgcttt
     3001 cccagcaaag ctttgactat caagtcttcc ttctccaaca acaaccaagt cagcatctga
     3061 aactttctta tcaaagttga ttaagtccaa gcaggtatca attccagaca cgatacttgc
     3121 ctgagcaaag gcacacaaac caccagcaag gcctccacct gctcctgctc ctttaatttc
     3181 taatgttgca ggtgagaatt tttcataaaa atcttggatc gcctgatcta cgactgcaaa
     3241 catagtcgga tgtagacctt tttgattgcc aaaagtgtaa gtcgcacctt gatgaccaca
     3301 taagggactc acgacatctg ctagaatatg aatttgaaca ccttcaggaa ttttatagca
     3361 attttctgtt gaaacagaag ctaagtttaa taaggattga tcggaagcag gcaagacatt
     3421 tccatcccta tcataaaatt gataacctaa accagcagca atccccagtc ctccatcatt
     3481 actggccgtg ccaccaacac cgatataaat atctttaatc cctttagaaa tgagatggag
     3541 aatcaactct ccaataccac aagtttggat ttgaagtgga tttcgtttct ctagcggaat
     3601 ttttccaaga ccaaccaagt cagctacttc aaatagtgcc agttcccctt tttgaaaata
     3661 gcgcatggct tctttttgtc cagaagggtc tgtcacttgg atccattttt cttttaggtc
     3721 aagagaatgt cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag
     3781 acattctaca tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg
     3841 agctgtcaag ctttccttaa acgaatccgg tgcaattaca atcttcatat tttccctcat
     3901 tctaaacagt caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt
     3961 atttcttttt tgagcatttc tttggaacaa aaggcgattc ctcactccgc cgacttcaac
     4021 attaatagat tattgacccc atcaccgatt gccaccgttc tttctttaga aagttttagt
     4081 ttctttctcc atttttccag agtttctttt ttgacctggg gacttataat ttgtccaact
     4141 aattttcctg ttaaaagacc ttctttgact tcaagctggt tggcagtgaa ataggcaata
     4201 ccaagggatt ttgctaatct ctccaactat tggtgtaaat ccaccagaca ccagaccaac
     4261 taggatgcca ttcttttgga gaatagagat gaactctggg acatttagcg atagatgaat
     4321 tgagttgaag acgttatcaa agaccaaaat aggaagacct tccaacaagg acactctttt
     4381 tcttaaactg ctttcaaaga ccaactctcc tcgcattgct cgacttgtaa tctgcgaaat
     4441 ttccgcctca tgacctgcct ctctccctaa aagatcaatc acttcttcta ggattaaggt
     4501 tccatctaca tccaaaacac acaagccttt tacttgagac atcagttctc ctctctaaac
     4561 agcctaaaaa tcgtatgaag tcatcatacg attttatcta ttaattaact aaactatggt
     4621 acaagtcaag gtatgacttg caggctgtat cccatgagaa gtcactctcc atagcttgtt
     4681 tttgtaggtt tctccaaatg tctggatggt ttctatacaa gtccaatgct gtttggaaag
     4741 tccaatttaa ccaataagga gatagattgt caaagctaaa gccagtaccg cttccttcga
     4801 ttggattgaa agcgcgaact gtatctcgca agcctccaac ttcatggacc aatggcaagg
     4861 ttccataacg catagccatc atttgagaca agccacacgg ttcaaaacga cttggcatga
     4921 ggaagaggtc acaagcagcg tagatttcct gagcaagttt gacatcaaaa gtgatatttg
     4981 ttgatagctt gtctgggtaa atctgagcaa accatgagaa agctccttca aaggctggat
     5041 cgccagttcc caaaagaaca atctgaacat cttcttgcaa gatatggtga agactttcga
     5101 ccaccacatc aaaacctttt tgacgtgtca aacgagaaac aattcccacc agtggaacgt
     5161 ctgctctaac aggcaagcca actctttctt gcaattttgc cttatttttg gctttcccag
     5221 acaaatcttc ctgattgaaa tgatagtcta aaagagcatc cgtctgagga ttataaagat
     5281 cagcatcaat cccattcacg ataccagata ctttaccaga ctccatttta agaatctgat
     5341 ccaaattaca tccaaactga ctagtcataa tttcatgagc atagctaggt gaaacagttg
     5401 aaacacggtt cgcatagaga atacctgcct tcatccagtt cagacagttg ttccatcgaa
     5461 gggtgccatc agcgtaacgt tcaaagccaa ctccaaacaa atcacccaac attccttctg
     5521 aaaattgtcc ttggaattct aaattatgaa tggttaaaac tgtttcaatg tcctcatagg
     5581 cttgaatcca acggtatttt tccttcaaca agaaaggaat catagctgta tggtagtcat
     5641 gaacatggag aagatcagga ataaagtcaa tcctttccat agcctcaatg gcagccagtt
     5701 ggaaaaaggc aaagcgttct ccgtcatcaa aatcaccgta aacatgacca cggaagaaat
     5761 aatattgatt gtcaataaag tagaaggtta caccatttaa tactgttttc ttaattccac
     5821 aatactgtct gcgccaacca acgctcacct caaaatgaag cacatcttca atctgacttc
     5881 caaatttagc ctctaccata tcatagtagg gtaaaatcac tgcaacttcg tgcccagctt
     5941 ttaccagtga ttttggaaga gcgccaatga cgtctcccaa accacctgtt tttgaaaagg
     6001 gtgcaccctc tgctgctaca aataaaattt tcatgaatga atatcctctg ttactttagc
     6061 acctttctta accacaactg gatgttctgc agttcctcga atcacaacac caggctcaac
     6121 ttcaacccct ttgtccaaga tagcatattc gacctgagcc ccttctccaa taacaacacg
     6181 agggaagagc aggctatctt taaccaagct atccttatgg acatgaatat tacgtgatag
     6241 aacagaatta gctacttgac cttcaataat actaccagag gcaaactgag aagtgcttac
     6301 cttagatgta ttagcatagt aagttggctc ttcgtttttg acctttgtat aaatcttttg
     6361 gtttggtgag aaaagagaat agaatttttg tgattcaagc atatcgatat tcgcttgata
     6421 ataagattta acagagtgaa tattggctag atagcccgtg tactcgtagg cgaaagctcc
     6481 ctcttttaca gccaaatccc gtaaaacata gcgcaatttc tctggatgtt cttttttagc
     6541 ttcttcttcc aagtgttcaa tcaaccaagg tgtatcaacg acaaagatat ctgtagacat
     6601 attgaacgtt tcagctgttg acttgctatc aaagagttta tgagaaagaa catggtctgt
     6661 ttcatctaca tccaagattg catttacttc tgaaatatct ttcttagcta gttttttata
     6721 aactacagtg ataggctctt ttgttgtact atgtaggtgg aaaacttggt tcaaatcaat
     6781 gttaataaga acatcgcagt tgagggcaac cgtttggttt gagccagaac gtttcaaata
     6841 agtaagaagc tgttggtagt attcttttcc aactgtacta ctttctacac gggtattgta
     6901 aattcctaga tagtaatggc taagaagggt tgataagccc cactcgcgtc ctgaacgaat
     6961 atggtcaaat actgagctga tattatcctg ctggaaaata ccaaagacac tacgaacacc
     7021 tgcattagca aggcttgaaa gtgggaagtc aatcaaacga tatttcccac caaatggcaa
     7081 acttgctact ggacggtggt ccgtcaatgt cgacatattg tgaaaaccaa ctgtatttcc
     7141 taaaatggca gaatatttat caatcttcat ctgttgctac ccccactact tcattatatc
     7201 ctacaacttg tacttcatct gttccatcaa tttcgacacc gtcagaaata atcgcacctt
     7261 caccaataat ggcacgttta atcttagctc cttgaccaat gatagctcca ctcatgataa
     7321 ctgaatcaag gacttccgct ccttcgcgaa cttgcgcgcc tgttgaaagg atagaatgtt
     7381 taacagttcc atcaacgaaa catccgtcta caactaatga gtcttccaca tgagcatttg
     7441 ccccgaggaa gtttggtggt gaaatcaagt ttcttgagta aatcttccat tgacggttac
     7501 gactatccaa ggcattttct ggagaaatat actccatgtt cgcttcccaa agtgactcaa
     7561 tagtaccaac atctttccaa taaccactaa attcataagc ataaacactt tcacctgact
     7621 caaggtaatt tggaatgaca tttttaccaa agtctgacat gccaaccttg ctcttttcag
     7681 cagcgactaa catattacga aggcgttgcc aatcaaaaat gtagattccc atagaagctt
     7741 ttgtagattt aggttgagct ggtttttctt caaattcaac aatacgattg ttagcatctg
     7801 tgttcatgat accaaaacgg cttgcttctt taagagggac gtctaaaact gctactgtca
     7861 agctggcatt attatcctta tgagactgga gcatatcatc atagtccatt ttgtagatgt
     7921 ggtccccaga caaaatcaag acatactcag gattgacact gtcgatatag tcgatatttt
     7981 ggtaaatagc gtgactagtc ccctcaaacc aacgatttcc ttcacttgca gaataaggtt
     8041 gaagaataga gacacctgaa ttaataccgt ctagtcccca gcttgaacca ttcccaatat
     8101 ggttgttgag agcaagtggt tgatactgtg taacgacccc aacattatga atccctgagt
     8161 tggcacagtt tgatagggca aagtcaatga tacggtagcg cccaccaaat tgcacagctg
     8221 gttttgcgat gctttgagtg agtttaccga gacgagttcc ttgcccacca gcaagaatca
     8281 aagctaacat ttcatttttc attttctact cctttttggt ttttatttgt gacggtttta
     8341 gtagatttca agcgacgttt gattttccat acacttgctc ccatagccgg tagagtaaag
     8401 gttaaggtct gctcataatc tttccatagt ccttcttgcg tttgaacagt ttgattatgt
     8461 tctttccaaa cgcctcccca ctcttccaac tcagtattcc atacttcttc gtaaattcct
     8521 gcaacgggta gtccgattgt aaaatctttc cgctcaacag gtaccatatt aaagatacag
     8581 actaacattt ctcccttttt acccttacga ataaaggaaa gaacactctg gtctcgatta
     8641 tccgcatcaa tgatttcaat accatcatag ctggtatcaa tttcccacag acagcgatga
     8701 tctttgtaaa actggtttag ctgagaagcg aaatacttca tcttagcatt cattgggtct
     8761 tctaggttag accattccaa ctgttcttca gatttccatt ctaggaattg accgtattcg
     8821 ctacccatga agagcaattt cttaccaggg tgacaaattt ggtacgtata gagattgcgc
     8881 aagcctgcga attgattgta acgatctccc cacatcttat gcatcatact cttcttgcca
     8941 tgaaccactt catcgtgcga gaatggcaag agataattct ccttgaaaac atacataaag
     9001 ctgaaagtca ccaggttaaa gtcatattta cgataaatcg gatcttcttc gtagaaacgg
     9061 aggatatcat tcatccagcc catgttccat ttgtagtcaa atcctagact accaatctct
     9121 ttcattcccg taatcttggt cgcagacgaa ctttcttctg caatcatcat cacatctgga
     9181 tattctaact taataacttc attcaagcgt tgaagaaaat aataaccttc atagttgaga
     9241 tttccgccat ctttattagg tgtccatgga gcattatcat agtccaaata gagcatgttg
     9301 ctaacagcat ccacacgaat accatccaaa tgatagacat caatccaatg cttaatgcaa
     9361 gaaattaaga aggactggac ttcatttttt ccaaggtcaa aattaagggc accccaacca
     9421 tggttatgag ccttattatg gtcttggtat tcaaaagtcg gtgtcccatc ataataggct
     9481 aaggcatcat cgttgatggt aaagtgacct ggtacccagt ccacaataac cccaatatta
     9541 tgggtatgac actcctcgac aaaatcttga aactcctctg gtctgccata agcatgctct
     9601 aaagcgaagt aacccataag ctgatacccc caactcaagc ccaaaggatg ggacatcaag
     9661 ggcataaact caatatgagt atagttcatt tcaacgagat aaggaatgag ttcatccttg
     9721 agctgggcaa aactataagg actgccatca gaatttcttt tccatgatcc agcgtgaact
     9781 tcataaatat tgacaggacg ctcttcaaag ccccaacgtt ttcttcgtgc cagccaaagt
     9841 ccatccttcc atttcttctc aggaagctct gttaagattg cccctgttcc tggacgagcc
     9901 tcatacctga cagcaaaagg gtcaatcttc atcagttgat gaccattttg acgtgtgaca
     9961 tgatatttgt aaatatgccc ttcttgagcc atattggtaa agacttccca gaccccaaaa
    10021 tcatttctta ccattggaat ctgattttca atccagttgg taaaatcacc aaccaagtga
    10081 acagcctgag cattaggtgc ccaaacacgg aaggtatagc catgctctcc atttagttct
    10141 tccctatgtg ctcctagata atgttggaga taaaaatttt cacccgtcat aaaggttttt
    10201 aatgcttctc tattatccat atactcccct tctcctgtaa gcgttttcta tgtttttatt
    10261 atactacctt tttagagaag attcaagtaa attactatac ttctttaatt attttgaaaa
    10321 tctacaacaa gttcacttac tcgttcaatt gtaaatcaat attttttcaa aaaattgcga
    10381 aaacgccttt ctttttctac tatagtgaaa tgaaataaaa catgcgcaag tcgattaagg
    10441 aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg
    10501 tactata
//
LOCUS       DAVBNN010000066        10492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBNN010000066 DAVBNN010000000
VERSION     DAVBNN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.066"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(26..628)
                     /locus_tag="VQ847_001797"
                     /pseudo
     CDS             complement(26..628)
                     /locus_tag="VQ847_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(1214..1990)
                     /locus_tag="VQ847_001798"
     CDS             complement(1214..1990)
                     /locus_tag="VQ847_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3051095.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            2112..2858
                     /locus_tag="VQ847_001799"
     CDS             2112..2858
                     /locus_tag="VQ847_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3051096.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2871..3851
                     /locus_tag="VQ847_001800"
     CDS             2871..3851
                     /locus_tag="VQ847_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3051097.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            4046..4366
                     /locus_tag="VQ847_001801"
     CDS             4046..4366
                     /locus_tag="VQ847_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3051098.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4412..4720
                     /locus_tag="VQ847_001802"
     CDS             4412..4720
                     /locus_tag="VQ847_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3051099.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4737..6035
                     /locus_tag="VQ847_001803"
     CDS             4737..6035
                     /locus_tag="VQ847_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3051100.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            6186..8624
                     /locus_tag="VQ847_001804"
     CDS             6186..8624
                     /locus_tag="VQ847_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3051101.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8643..9311
                     /locus_tag="VQ847_001805"
     CDS             8643..9311
                     /locus_tag="VQ847_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3051102.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGATSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9329..10417
                     /locus_tag="VQ847_001806"
     CDS             9329..10417
                     /locus_tag="VQ847_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3051103.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         3438 a         1491 c         2085 g         3478 t
ORIGIN      
        1 aatttgtcct gttcttattt cattttacta taccatcaat aagtgtgaaa agatctttta
       61 cataagacca agccttatta tctttgtaac caccttgagc ttgtagcata tttgttaatt
      121 gagcaaaggc gctagaagag tttgctgggt cagcagttgc gatttttcct tttagttcag
      181 gtttgagaag gtcgctatat ccttcgatgt tcatgccttt agttaaatca gggtggacga
      241 ttaaaacact accatctagt gtataaggag tagagaagcc agttgtgttt tgatattctt
      301 tgataacatt atcattttct tttgaaatat agttttcaaa gagttctccg tgggtagcat
      361 attgtgtata agaaccacca aagataacat cagctacagg aacttctttt tctgactcta
      421 gttttttgaa aagttctcca gtaccagctt gaatcagttc tattttgata ccatattttt
      481 cttcaaaggc aggaatagtt gctccaatta agccttctga gtttggtgaa taaacgacta
      541 gcgaaccacc gtctccttta tcagatgaac tgtcatcggc agattcatta gaagaacaag
      601 cagcataata catccatttc tttttcatga tggatacctc cgttgtgtta tttaagttta
      661 ttttaaaaca atgtaagcgt ttttaaaacc tacaattcta ttctatagtg tattgaatct
      721 ataacagtac accttgactg ctaaaatatt tctataaatt aatttgactt tcctgataga
      781 gatgttcaca tcttatttca attcactata ttagagtaaa attctctaca aaaaaaagaa
      841 tagcctattt tactattttt ccgagtgatt tcaattcctt tggggaaata tggagatact
      901 ttttaaatcc tgacaaatgg ttgtttcttt ttctaaatcg gtgatactgt atcggagaat
      961 gcgcgtgagg tcacaaaggc tgcgatagag cttctatgga gaatttcttt ttggagagat
     1021 tttttaaagg aatgagacat ccgctacctc cttggaaggt tttttgtgat aagtatagca
     1081 gtttaaaaat tctagagcaa ggtaaaatag aaaaggtttg gctaaaattt tttagctaaa
     1141 ccttttgaaa agttaagtat gtattataga tgcttgttat ctgcaaatat ctagagcatt
     1201 tcaaggaaat aaactagaaa taacaattaa tatggtggtt cagaaatacc ttttgataat
     1261 caataagatc ttcaggatga agtgcgttga ctccatccat ttcatatttc cgatttaata
     1321 aacgatattt gttttcacca aattgatgaa aagggagtag ttgaacttgg tcgatattta
     1381 atgagttaaa tagagtagcg aatttttctg catcctctaa actattgtta aaattaggaa
     1441 taactgggat tcttaaaacg atagttttat tttgagaaaa agcataatga atgtttttaa
     1501 taatcatttg attaaaaacc ccagtcactt ttttatgttt tatagaatta taatgtttta
     1561 ggtctgtgta gataaaatcc acatattgaa ttaaatcgat aaatttttca tgatcaacaa
     1621 aggcagtagt ttcaatggca gtgtgtatgt gatgttcttt agctgatttt aagatggctt
     1681 tagcaaattc aaactgagca aatatttcac ctcctgataa agttaaacct ccaccggatt
     1741 cttcgtaaaa ttctttgtct tttaatacct ctgtaataat ttcttctaca gtcttttctt
     1801 caccgactaa ggtgaatttc tctcgttgag catctttcat tttttcaggt ttcattcttt
     1861 gagattcagg attagaacac catggacagc gcagaggaca tccttttaaa aaaacagttg
     1921 tacgaatacc cgggccgtca tgaattgaaa agtgttgaat attaaaaata attcctttag
     1981 atatttccat aagagttcct cctcttcata agtctatcct atcacaaaaa cgaaagaaaa
     2041 acaattacga acgaaaggtt aatttgttgt tttttgcttt ttattttggt agaataaaac
     2101 ggaggtgtaa aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa tatgaaaaga
     2161 tcgacgttaa tacattatcg gaaaaattaa atgtatcgaa agtaacgatt agaaaagatt
     2221 tagataaatt agagtcaaaa ggtttattac acagagagca tggatatgct gtattaaata
     2281 gtggagatga cttaaatgta cgtttgtcaa ttaattatga aattaagaga aaaattgttc
     2341 aggaagcagt aaaattggtg tcagataatg aaacaataat gatagaatct ggatcgacct
     2401 gtgctttact tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt gtaacaaatt
     2461 cattttttat agcaaatttt gtgagagctt atgattcatg tcgtattatt gttcttggtg
     2521 gagagtttca gaaggattca caggttactg tgggaccttt attaaaagaa atgatacaga
     2581 cttttcatgt gcgtcaagct tttgttggga cagatggcta cgataaagag atgggcttta
     2641 caggaaaaga tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg tcggataaag
     2701 tcattgtact aactgactca agtaaatttg ataaaagggg tacagtaaga agatttgctt
     2761 taagtcaagt ctatgaagta ataacagacg aaaaactttc taaacaaaat atagctacat
     2821 tagaaaatgc tgggataatg gttaaggtag tttcgtaaga ggttaagtgt atgaatcaag
     2881 ataggaataa actgctctct aaaattgctt atctgtatta tattgaaaac ttaaatcagt
     2941 cacaaatagc agcaaaatta ggaatttata gaacctctat tagtagaatg ttaacagaag
     3001 caaggaatgc aggaattgtt aaaattgaaa tagagaattt tgataccaat atgtttaagt
     3061 tggaaaatta tgtaaaagaa aaatatggtc tggaaagttt agaaattatt ccaaatgaat
     3121 ttgatgataa tccaacaatt ttatctgaaa gaatttctca agttgcagca ggtgtcctta
     3181 ggaatctaat tgatgataat atgaaaattg gcttttcttg ggggaaaagt ttaagtaatt
     3241 tagtagattt aattcacagt aaaagtgtcc gaaatgttca cttctatcct ctagcaggtg
     3301 gtcctagtca catacacgct aaataccatg tgaatacact gatttatgaa atgtctagaa
     3361 aatttcatgg agagtgtaca tttatgaatg caacgattgt gcaagaaaat aaattgttag
     3421 cagatggtat tttgcaatca agatattttg aaaatttgaa aaatagttgg aaagatttag
     3481 atatagctgt agtcggaatt ggtgatttta gcaataaagg aaagcatcaa tggttagaca
     3541 tgcttacaga ggatgacttt aaagaattga ccaaagttaa aactgtagga gaaatttgtt
     3601 gtcgattttt tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa agaacgatag
     3661 caatctcttt ggaagattta aaaaatattc ctcaaagttt agctgttgct tacggtgata
     3721 cgaaagtatc ttcgattctt tctgtcttgc gtgctaattt agtaaatcat ttgattacag
     3781 acaaaaatac aattttaaaa gttttggaag aagatgggga tttgactttt agagagattc
     3841 taggtgagtg aaaatgatag actgattcag tttatcgttt ttctttttag ttgattgcac
     3901 atttgtgctt atataaacaa aaatagttta tctgttgttt ttggattgac aactttatta
     3961 tgtagttgta ttctatagtt acaaaagaaa attttaaaat ttcaaatgaa aaaagctttt
     4021 tacatagtga aatgaggagg aatttatgga aattattgtt ccagatcaaa ttatcatggg
     4081 tttaatttta tatgctggcg atgcgaaaca acatatttat aaagcattag attacataaa
     4141 gaacggtaca tgtgaacgat gtgaagaaga aatccagtta gctgatgccg ccttattaga
     4201 agctcataat ctacaaacaa aattcttggc acaggaagcg tctggtacaa agacagaaat
     4261 tacagctctc tttgttcatt cacaagatca tctcatgact agtatgacgg agattaattt
     4321 aatcaaagaa attattagtt tgagaaaaga acttcataaa aaataatact agagtattat
     4381 cattgttatt aacatagagg aggaaaacat aatggtgaag attggtttgt tttgtgcagc
     4441 aggtttttct actggtatgc ttgtaaataa tatgaaaatt gcagcgcaag ctagtggagt
     4501 tgaggcagaa atagaggcgt tttctcagtc taaattagcg gattatgcgc caaatataga
     4561 tgttgcacta ttgggtccac aagttgctta tacattagat aaatcaaaag aaatttgtga
     4621 taagtgtgat gttccgatag ctgttattcc gatgatggac tatggtatgt tagatgggaa
     4681 aaaagtatta gatttggccc tatctttgat tagtgggtaa gaaaaggaga tttattatgt
     4741 caaagatgga tgttcagaaa atcattgcac cgatgatgaa gtttgtgaat atgcgtggca
     4801 ttatagctct aaaagatggg atgttagcaa ttttgccatt gacagtagtt ggtagtttgt
     4861 tcttgattat gggacaattg ccgttcgaag gattaaataa gagcattgct agtgtttttg
     4921 gagctaattg gacagagccg tttatgcaag tatattcagg aacttttgct attatgggtc
     4981 taatttcttg tttttcaatt gcctattctt atgctaagaa tagcggagta gaggctttac
     5041 cagctggagt tctatctgta tctgcattct ttattttgct aagatcatct tatatcccta
     5101 aacaaggtga ggcgattggg gacgctatta gtaaagtttg gtttggaggc caaggaatta
     5161 tcggtgctat cattataggt ttggtagtag gaagtattta taccttcttt ataaagagaa
     5221 aaattgttat taagatgcca gaacaagttc cacaagctat tgccaaacag tttgaagcaa
     5281 tgattccagc atttgtaatt ttcttatctt ctatgattgt atatatttta gcgaagtcat
     5341 tgactaatgg cggaacattc atagaaatga tttattctgc tattcaagtt ccgttgcaag
     5401 gtttaactgg atctttgtat ggtgctattg gaattgcatt ctttatatca tttttgtggt
     5461 ggtttggtgt tcatgggcaa tcggtagtaa atggagtagt gacagctctg cttttatcta
     5521 atcttgacgc taataaagct atgttagcct ctgctaatct atcattagaa aatggtgcac
     5581 atattgttac tcaacaattt ttagattcat ttttaattct atcaggttca gggattacgt
     5641 ttggtcttgt agttgccatg ctttttgcag caaaatcaaa acaataccaa gccttaggaa
     5701 aagttgcagc ttttccagca atatttaacg taaatgagcc agttgtattt ggatttccga
     5761 ttgtcatgaa tccagttatg tttgtacctt tcattcttgt tcctgtactt gcagctgtga
     5821 tagtatatgg agctattgca acaggtttca tgcagccatt ctcaggggta acattgcctt
     5881 ggagtacacc agctattcta tcaggatttt tggtgggtgg atggcaaggt gttgtgactc
     5941 agttattagt attggtgata tctacagtgg tttactttcc attctttaag atacaagatc
     6001 gtttagctta ccaaaatgaa atcaaacaat cttagaggta tttgtgtgtt actgttaaac
     6061 tcacacattt gtgctaaaaa ttagagagtt aaaatttttc tagttaaaag cttgaaaatt
     6121 tctataaaaa tcggtattat attttcgaaa gaaataaaaa tattttcgaa agaaaggtgc
     6181 ttacgatggt aaatacagaa gtagcaagaa caacaatcaa gacagaatat tttggcagcc
     6241 ttactgaaag gatgaacaaa tatcgagaag atgttttaaa taaaaaacct tatattgatg
     6301 ctgagagagc agttctagca acacgcgcct atgaacgata caaggaacaa cctaatgtcc
     6361 taaaacgtgc atatatgctg aaagaaattt tggaaaatat gtctatctat attgaagaag
     6421 aatctatgat tgcgggaaat caagcttctt ccaataaaga tgctcctatt tttccggaat
     6481 atacgctaga atttgttctc aatgagttgg atctttttga aaagcgtgat ggagatgttt
     6541 tctatattac agaagaaaca aaagaacaac ttagaagtat tgctccgttt tgggaaaata
     6601 ataatttacg tgctagagct ggtgccttat tacctgaaga agtgtcagtt tatatggaaa
     6661 caggattctt cggtatggaa ggtaagatga attctggaga tgctcactta gcagttaact
     6721 atcagaaact tttgcaattt ggtttaagag gttttgaaga gcgggctcgt aaagcaaaag
     6781 tagctctaga tttaacagat ccagcaagta ttgataaata tcatttttac gactctatat
     6841 ttatcgtaat cgatgctatt aaagtatatg caaagcgctt tgttgctctt gctaaaagtt
     6901 tagccgaaaa tgcaaatcct aaacgtaaga aagaattact tgagattgca gatatttgct
     6961 ctagagtccc atatgaaccg gcaactactt ttgcagaagc tattcaatca gtttggttta
     7021 ttcaatgtat tttacaaatt gaatctaatg gccactctct ttcatatggc cgttttgatc
     7081 aatatatgta tccatatatg aaggctgatt tagaaagtgg taaagaaaca gaagatagca
     7141 ttgttgaacg tctgacaaat ctttggatta agacaattac aattaataag gttcgcagtc
     7201 aatcacatac attttcttca gcaggaagtc ctttatatca aaatgttaca attggtggac
     7261 agactcgaga taagaaggat gctgttaacc cattatctta tttggtatta aaatcagttg
     7321 cacaaaccca tctaccgcaa cctaatctaa ctgtacgtta ccatgcaggt ttagatgctc
     7381 gtttcatgaa tgagtgtatt gaagtgatga aacttggttt tggtatgcct gcatttaata
     7441 atgatgagat tattattcct tcttttattg caaaaggagt attggaagat gatgcttatg
     7501 attacagtgc cattggatgt gttgaaacgg cagttccagg gaaatggggc tatcgttgca
     7561 caggtatgag ttatatgaac ttccctaagg ttctacttat cacgatgaat gatggaattg
     7621 atccggcttc gggtaaacgg tttgcaccaa gctttggtca ttttaaggat atgaagaact
     7681 tttctgaatt agaaaatgct tgggataaaa cactaagata tttgacacga atgagtgtta
     7741 ttgttgaaaa ttctattgat ttatcattgg aacgagaagt tcctgatatt ctatgttcag
     7801 cattgactga tgattgtatt ggtcgtggaa aacaccttaa agaaggtgga gcagtatatg
     7861 attatatatc aggattgcaa gttggaattg caaatttgtc ggattcatta gctgcaatta
     7921 aaaaattggt gtttgaggaa gaacgtataa gcccaagtca gctttggcat gcactggaaa
     7981 cagattatgc cggagaagaa ggtaaggtca ttcaagaaat gttgattcat gatgcaccta
     8041 agtatggtaa tgatgatgat tatgctgaca aattggttac tgctgcttat gacatttatg
     8101 ttgatgaaat tgctaaatat cctaatacac gttatggaag aggtccaatt ggaggaattc
     8161 gttattcagg aacatcttct atctcagcca acgtagggca gggacgtgga acattagcaa
     8221 ctccagatgg acgcaacgcg ggtacaccgt tagcagaggg ttgttcacca tcacataata
     8281 tggatcaaca cggccctaca tctgttttaa aatctgtttc aaaattacca acagatgaaa
     8341 tcgtaggtgg ggttctctta aatcagaaag taaatcctca aacgttagcc aaagaagaag
     8401 ataaattaaa actaattgct ttgttacgaa cattctttaa tcgtttacat gggtaccata
     8461 ttcaatacaa tgttgtttcc agagagacgt tgattgacgc tcagaaacat cctgaaaaac
     8521 acagagactt aattgttcgt gttgcaggat actctgcatt cttcaatgtt ctttctaagg
     8581 caacccaaga tgacattata ggacgtactg agcatacttt gtaaaataaa gaggttcttt
     8641 ttatggaatt tatgcttgac acattaaatt tagatgagat taaaaagtgg tctgaaattt
     8701 tgccgctagc tggggcaact tcaaatccca ctattgcaaa aagagagggt tctattaatt
     8761 tttttgaacg aatcaaagat gtaagagaat tgattggctc cacaccctct attcatgttc
     8821 aggtgatttc tcaagatttt gaaggcatct taaaggatgc tcatgaaatt cgaagacaag
     8881 caggagatga tatatttatc aaagtacctg ttactccagc tggattacgt gcaataaagg
     8941 tgctaaaaaa agagggctac catatcactg caacagctat ttatacagtt attcagggat
     9001 tattagctat cgaagtagga gcggattacc tagctccata ttataataga atggaaaatc
     9061 tgaacattga ttcaaattct gtcattcgtc aattagctct tgctattgat agacagaact
     9121 ctcctagtaa gattttagct gcatccttta aaaatgtagc acaagtaaat aatgctttag
     9181 ctgcaggtgc gcatgctgtt acagcaggag cagatgtttt tgaatcagct ttcgccatgc
     9241 catctatcca aaaggcggtt gatgattttt ctgacgattg gtttgttact caaaatagtc
     9301 gttccattta gatagagagg aaatacatat gagaattttt gctagtcctt ctagatatat
     9361 tcagggggaa aatgccttgt ttgaaaatgc caaatcaatt ttggatttgg gaaattaccc
     9421 tattctatta tgcgatcagt tggtttatga tattgttgga aaacgatttg aagattatct
     9481 acataggtat ggtttccata ttgttctggc gctatttaat ggtgaagctt ctgacaatga
     9541 aatcaatcga gttgttgcct tggctgagaa agaaaattgt gatagtatta tcggtcttgg
     9601 tgggggaaag acgattgata gcgcaaaagc tattgcagat ttgattgaaa agcctgttat
     9661 tattgctcca acaattgcat cgaccgacgc acctgtatct gctttatctg ttatttatac
     9721 agatgaaggt gcatttgatc attatctatt ttattctaaa aatccagatt tagttttggt
     9781 tgatacaaaa gttatttcac aagcccctaa gcgtttatta gcgtctggta ttgcagatgg
     9841 tttagcaact tgggttgagg cgcgtgcggt tatgcaggca aatggaaaaa ctatgttggg
     9901 acaacagcaa acattggctg gagttgcaat tgcgaagaaa tgtgaagaaa cgctgtttgc
     9961 agatggttta caggctatgg cagcttgtga agctaaagtg gtgacaccag cattagaaaa
    10021 tattgttgaa gctaatactt tattgagtgg cctaggtttt gaaagtggag gattagctgc
    10081 ggcgcatgca attcataatg gttttactgc attgacaggc gacattcatc atttaacaca
    10141 tggtgaaaaa gtagcttatg gaactttagt acaactatta ttggaaaata gacctaaaga
    10201 agaacttgat aagtatattg agttttacaa aaaaattggt atgccaacaa ctctaaaaga
    10261 aatgcatttg gatcaagttg gatatgatga tttaataaaa gttggtaaac aagcaactat
    10321 ggagggtgag acaattcatc agatgccgtt taagatttcg ccctcagatg ttgctcaagc
    10381 tattatcgct gtagatgcct atgtaaattc aaaataaaca ataaggacta ctgttttcca
    10441 aatggtagtc ttttattgat ccctgtattg aattctatag aagattgaaa ta
//
LOCUS       DAVBNN010000067        10425 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBNN010000067 DAVBNN010000000
VERSION     DAVBNN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.067"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(100..903)
                     /locus_tag="VQ847_001807"
     CDS             complement(100..903)
                     /locus_tag="VQ847_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3051104.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1178..1933)
                     /locus_tag="VQ847_001808"
     CDS             complement(1178..1933)
                     /locus_tag="VQ847_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3051105.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2003..4654)
                     /locus_tag="VQ847_001809"
     CDS             complement(2003..4654)
                     /locus_tag="VQ847_001809"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3051106.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4647..5225)
                     /locus_tag="VQ847_001810"
     CDS             complement(4647..5225)
                     /locus_tag="VQ847_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3051107.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5225..5785)
                     /locus_tag="VQ847_001811"
     CDS             complement(5225..5785)
                     /locus_tag="VQ847_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3051108.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(5772..6221)
                     /locus_tag="VQ847_001812"
     CDS             complement(5772..6221)
                     /locus_tag="VQ847_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3051109.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6634..7029)
                     /locus_tag="VQ847_001813"
     CDS             complement(6634..7029)
                     /locus_tag="VQ847_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3051110.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7125..7379)
                     /locus_tag="VQ847_001814"
     CDS             complement(7125..7379)
                     /locus_tag="VQ847_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3051111.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7389..8723)
                     /locus_tag="VQ847_001815"
     CDS             complement(7389..8723)
                     /locus_tag="VQ847_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3051112.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8723..8956)
                     /locus_tag="VQ847_001816"
     CDS             complement(8723..8956)
                     /locus_tag="VQ847_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3051113.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9224..9364)
                     /locus_tag="VQ847_001817"
     CDS             complement(9224..9364)
                     /locus_tag="VQ847_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051114.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9361..9543)
                     /locus_tag="VQ847_001818"
     CDS             complement(9361..9543)
                     /locus_tag="VQ847_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051115.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(9545..10324)
                     /locus_tag="VQ847_001819"
     CDS             complement(9545..10324)
                     /locus_tag="VQ847_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051116.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         3027 a         2332 c         1932 g         3134 t
ORIGIN      
        1 tttggggtca gtacatttta acacttgata ctatgcgttt tattgtggga atgtttactt
       61 cattttttcc taaaattcaa tgtttactca gtatttggat tatgaaaaat cgaggtctaa
      121 atctagatac attttttctg aagacaaatc attttgacca ccgagcaaga gattttcaaa
      181 aaaagctgtt aaaaactcag gacgtcgctg taaaatcttt gcattatcta ataccaaggc
      241 atcacgaaaa tacttggaat gttgctgaaa tggtatatta tcaatatcaa aaccaaactc
      301 acgaagatac tgaatcaaaa agaccgttac tgtccgagtg tttccttcgc gaaatggatg
      361 aatctgccag attcctgaaa taaaatgctg gatttgttta accacatccg cctgagttag
      421 tgtcgcatat gcaacttgtt tttcctgatt aaaatcataa tctaaggtca tttgaatcat
      481 ggagtaatca gagtacacaa cactttcacc attcaaaaca ggttcattct ttgtgatatt
      541 ggtctgacga aattgcccca ccggaataga gggttcaaat atatcttgaa acaactcctt
      601 atgaatagca agtaaggtcg caggactaaa gctaaagcct cttcgagaca atagttctac
      661 aatacgtaga gaaaccaagt ctgcctcttc cgtacttgca tcaatagtat ggtgataagc
      721 cgttgcatcc tcataaacct gctcataagt cagttctccc cgggactgtt tctcagccaa
      781 agattccata tacgctgatg gcactagatt gtcaactttc tgcagaccaa aacctatccg
      841 ccataaatca cgcttcgctt cataagacaa gtttggattg tcaatgttgt aagttgattg
      901 catagaaata tcctttcaat tgtttttctt cattaccagt aaatcacgaa attggttgga
      961 aactggctta aactataaaa agtcctcaca ataggttcta tgatatatat atacttcatg
     1021 taaataataa aagagttata atcagcacta ctgataaatt caataccgat ttcgccatct
     1081 taaaacttag tcaaacgaat accgttgatt tccagttcat taagtcgttg acctgtcaag
     1141 acttctcgtt ccttcaactg gaaaagttaa gggggaacta atacaaatcc tctacgcttc
     1201 tatattcaat gatttcattt tttataatat tctttttaaa ctcaaaatgt tttagaggat
     1261 tatcaactaa tactaacttt ggaatatcat ctaggttggt gaccagagat aaaataaaat
     1321 ctgattgaaa ctctttagct ttctcaaatt cgtaggcagt taaacggaca cgacccttag
     1381 gttttcgaat ccctttaact tcggcaaggt aggaatgttc ttgaatatct acttggaaat
     1441 catatccatc accataaaga catgcatcgg ttaactgtcc accttgaaat ttttcttctt
     1501 tatcaaaatg aaggataaaa taattctctg cctccatccc cgtttcctgt agacgtttga
     1561 atttagttcg aataattggt ttttcaatta tagtaatgcc tgtttgcttt ccttcactag
     1621 caagtaacat tttaacaatt tcaacataac tatgaacatc ttcatttcca aacatcatat
     1681 caattaaatc tttacgaaaa cggtaaactt cagctttctg ccaccaacct tttcgactat
     1741 tgtcaaaata aggatcaaat aaatccattc tattttttac aactccagtt gtttcagcaa
     1801 ttcccaaaga aaccacatag cgataaaact ccgacttact agaatattga aattctttta
     1861 taaaaagctt ggcaaacttg gcaagaccgt agccaattaa atttaacaat tcataatgcg
     1921 ggtgtttaga catcactttc tccatcaata gatagtaatt tcattatccc aaaaaacacg
     1981 gcattacacc atgtttctgt gtttatttca ccaacttctt catctcatca atacgtgcta
     2041 cggtcgcatc atacttggct tggtagtcag cttgtttgtc gcgttctttt tggacgactt
     2101 ctggtttggc gttggctacg aagcgttcgt tagagagctt cttaccgacc atgtccagtt
     2161 ctttttgcca tttagcaagt tccttgtcaa gacgagccag ttcttcttcg acattgagga
     2221 ggtcagccaa tggcaggtag atttctgctc ctgtaatgac gcttgacata gccagttcag
     2281 gtgcagggat ggttgatgcg atttccaagt gttctggatt tgtaaagcgt ttgatatagt
     2341 tgacattgct gttaaagaag gcttccaagt cgctatcgct tgtcttaaca aggatggtga
     2401 taggcttgct tggtgctacg tttacttccg cacgcgcatt acgaacggca cggatcaagt
     2461 ctttgagact ttctacacca gtatgagccg caaggtcttc aaaggctaga ttaacagttg
     2521 ggtatgcagc tgtcacgata gaaccttctg agatttgtcc aaagatttcc tctgtcacga
     2581 atggcatgat tgggtgaagg agacgaagga tcttgtccag agtgtaaagg agaacagatc
     2641 gagtaatgac cttatcgtct tcattgtcgc tgtaaaggac ttccttggtc aattcaacat
     2701 accagttggc aaattcttcc caaatgaagt tgtaaaggat atgaccagcc acaccaaact
     2761 cgaacttatc aaagttttca gtaacttttg caatggtttc gttgagattg tggagaatcc
     2821 agcggtccgt cacattacca gcctcacctg ttgcaacttt tgtgacattg tcatgcgcca
     2881 catccagcgt caaaccttca ttgttcatga ggatatagcg agaaatgttc caaattttgt
     2941 taataaagtt ccatgaagca tccattttct cgtaagagaa acgaacgtct tgaccaggag
     3001 ctgagccgtt tgacaagaac caacgaagac tatctgtacc atatttatca ataacatcca
     3061 ttgggtcaat gccatttcca agagatttag acatcttacg tccttcttca tcacgaatta
     3121 gaccatggat aaggacgttt tggaatggtt gacggcctgt gaattccaat gactggaaga
     3181 tcatacgaga cacccagaag aagatgatgt cgtaacctgt taccaaggtt gaagttggga
     3241 aataacgttt aaagtcttct gagtcaactt caggccagcc catggttgaa aatggccaga
     3301 gggcagaact gaaccaagta tccaagacgt cttcgtcctg agtccatccg tcaccttctg
     3361 gagcttcttc gccgacatac atttcaccat cagcattgta ccaggcaggg atttggtgac
     3421 cccaccaaag ctgacgagag ataacccagt cgtggacatt ttccatccat tgaaggaagg
     3481 tatcgttgaa acgaggtggg tagaattcga ccttgtcctc tgtgtcttgg ttggcaatgg
     3541 cgttcttagc caattggtcc atcttgacga accattgagt agacaagcgt ggctcaacta
     3601 cgacacctgt ccgttctgag tgaccgactg aatggacacg tttttcgatt ttgacaaggg
     3661 caccgatttc ttccaactta gcaacgactg ccttacgagc ttcaaaacga tccatgcctg
     3721 aaaattcaaa ggcaagctca ttcatagttc cgtcgtcgtt catgacgttg acttgtggca
     3781 agttatgacg ttggccaacc aagaagtcat ttggatcgtg ggcaggtgtg attttcacga
     3841 caccagtacc aaactcagga tctgcgtgct catctccaac gattgggatg agtttattag
     3901 cgattggaag gatgacgttt ttaccaatca agtccttgta gcgcgggtct tctggattaa
     3961 ccgcaaccgc aacgtcccca aacatagtct caggacgagt tgtagcaact tcaagggcgc
     4021 gtgaaccatc ttccagcatg tagttcatgt ggtagaaggc accttcgaca tccttgtgaa
     4081 tcacctcaat atcagaaagg gctgtgcgag ctgctgggtc ccagttgatg ataaactcac
     4141 cacggtagat ccagcctttc ttgtaaaggt ccacaaagac cttacgaaca gcttttgaca
     4201 aaccttcgtc aagagtgaaa cgctcacgag agtagtctac agagagcccc atcttgcccc
     4261 attgttcctt gatagtagtg gcatattcgt ctttccattc ccagactttc gtcaagaaag
     4321 actcacgacc aaggtcatag cgggaaatgc cctcaccacg caagcgctcc tctaccttag
     4381 cctgagtggc aatccctgcg tggtccatcc caggaagcca aagggtatca aaaccttgca
     4441 tgcgtttttg acggatgata atatcttgca aagttgtatc ccaagcgtga ccaaggtgaa
     4501 gtttacctgt aacgtttggt ggtggaataa cgattgaata aggcttagcc ttttgatcgc
     4561 ctgaaggctt gaaaacatca gcatcaagcc atttttggta acgaccagcc tcaacctcgg
     4621 ctggattgta tttagatgaa agttctttag acatgtgtgt gtcctttctc tattttgttt
     4681 attttatttt gaatttgctt agcagcttct tctgcagaca aattcgtatt atttatttta
     4741 aagtagtggt gcaactcatt cggttgatat tgggaattta attgaagtgt ttcagcggtc
     4801 tctaaaattt ctctttcaga tacctcaata tgtcgtttta agggtttgtg ctttaatcga
     4861 ttctccgttc gatttcgacg tatgcactct tcaagacttg tttccaactc aacaaaaaga
     4921 atctcttgat gataatcatc caacaaattc tgaatttgct ttaaatatat cagatgatac
     4981 tgatttgaaa aatcaattac atctgttaaa attactgatc gctgatttct tgcacttgct
     5041 ccaaggaatg aaaaagtgat tccacgaaca aattcccaca tttcctctgt atagtcctga
     5101 tagatttcta gtgcaaaatc aatggcttga tggttataaa atagggtagc atccgtcagt
     5161 cgagataatt cttgaccaat ggtcattttt cctgatgctg gagcaccaat gatgaaaaga
     5221 tgcatcaaat caccccccac tcactcttca gcaaggcata tctcaaatca tcacagcagt
     5281 tgccttgagc atctttacgg tctcttatgc gagcttcgag ggtaaagcca agcttttccg
     5341 cgactcgttg actttgaagg ttatatccaa agcaagttag ttcaatcttg tgaagaccca
     5401 aatctttaaa ggctaagtca atcaaggcac gcgcagcttc tggcacataa cctcgccccc
     5461 aatagtctga gtgtaaggta tagccgattt ccatcacatc atcttcatgg cgatggttga
     5521 aatagataga gccaacgatc ttatccgttc ctttgacgac aatcccgtag cctgctggga
     5581 gattttcctt ttgattacgc tccggaagaa tgtgctccag ataataaatc tcatcttcca
     5641 aggtcttgac tggaggaaaa cctgctggat aggcgacctc tggcaaacta gcatagtcaa
     5701 agatatcctc agcatccgcc acagtacgga ctcgtaaaac gagacgttct gtttcgattt
     5761 tatctggcag ctcagttctt gccatccttc ttcctcgctt ttttgatgaa actgcccttc
     5821 atatctacac gcttgtccag atagcgataa acgcgctgat atccatctcc catgaaatag
     5881 gttggggcaa acagttgatt tttaaaatgt cccttttcat ccaggagttc tggggcaaca
     5941 agtcgctcaa gaatcttggc aaagatgtgg caaataccgt cttcctcaac aatcctatct
     6001 acccgacaat ctaaaacaag tggacaggcg tctaaaatag gagtctgagt tcgttcagaa
     6061 atttcataat gcactcccaa acgttccaat ttctcctgat gactgataaa accagcctgc
     6121 tccatcgcaa gcatagaagt ttcatcagaa atattcacag taaatttttg atactgtttg
     6181 atctgctctg cggcattctc tctcgcaacg actccaatca caacccaatc tcctagacta
     6241 taagaggaac tacaggtcgt gatgttatag ccaaaattct aatcttgata tcctaaaata
     6301 aaaacaggaa aaccataata tagtttactt gtgttaaaag attgcttcat aacaaccccc
     6361 tttgactaag acgtaaaaga aaagccctgc catctacatg acagggacga atgtgtttat
     6421 ccgcggtacc acccaatttc gggcagttgc ccgcaactct cgtctttaaa gcaaaaagac
     6481 acttttattt caatttttca tccattagca accagttttg acacatttgt ggacttctca
     6541 gcgccgccac tttctgtaaa atgtgggatt caaaacacct ctaatggctc tattgtagca
     6601 agattttttc ggaaatgcaa ggctcaagaa aaattacttg aacttgatgc cattttcttt
     6661 caatttcttg atggtagctg ggccgattcc tttcaagtca aggagttctt tttcagtcca
     6721 gtttttgaaa tgtgaagcag acttgattcc ttcatcatag aaagtcttgg cacgatcaag
     6781 tggaagtcca cccaaatttg ctgcaaaatc ttctacagaa ttagctactt tttgagcttg
     6841 ctctttggta gcttctactg cttgttcaac ttttttagaa acagccttac cagctgcgct
     6901 tgctgtctgt tctgcacgct tcacgacttt ttttgtctca tctacaacct tagtcacagt
     6961 acttgaaaag gcacctgcgc gacggaggcc atttcgtaat tgttttttac gattgagttt
     7021 ctttgacatg ataaaatcct ttcaataaaa aatccctgct ctgacaagga tttaacataa
     7081 acattctatc aagattttag tgaaaaatca agaatctttc tcgtttaata atttcgctca
     7141 ccaaacaagc cttctggcaa atcatggaat cccttgccta ctttgaagtt ttcaaactta
     7201 ccaagcaaga actgataagc atccaagcga ctctcgtagc gaatcatggc atctttggca
     7261 cgctcgtcct ggtcttcttc gtaaactttt tgactttcct tgtgcgccat atcgttaatc
     7321 atgatttggg tattgaccca agcttcaaat tccttcataa attcttgttc gtaactcatt
     7381 ttttctcctt attctaatcc acgaaaatag tccgtatcaa tctcacggta gggctggata
     7441 tcctgaacat actccaacac tccttggaat tctccgtctt catcgtgtac tgcagcatag
     7501 gtgatgtgga caaacttacc tcgcgactca gacttgaacc acatttcata cttgtccttg
     7561 gtcccctcac gaagtccctt catgatagcc ttgaccttgt ccaaatactt aggcggatga
     7621 cagagttcga cattgcgccc gacttgggac ggcgtccgtt tgaaaatcat ctcatcagct
     7681 ggcgtattgt cattgtaata ctggaaaata tcttctttat tgacaaaggt aatctccata
     7741 gggagatgat tgaggatgag attggcctgc tcgactgaaa gatagccatt accaaaagcc
     7801 tgttgactat ggcggtccag cacagcttcc ttttccttag gggtaaaggt aatggtaaaa
     7861 tggccttctg gcgtatctat gacttgttga acttgacctt ctgccgtatc tagttgtaca
     7921 ggctcctctg caatcttttc ctcaataaag atctgtcgtt ctggcaccca tttctctgac
     7981 ggacggatga tggcatagcc ataggcatca ctctcctccg caatctgaag ccagtcatcc
     8041 tgagtaaaag actcaaggag aatcatgagc aggatggact cttccttgaa aatcatactt
     8101 tcaaactctg tcgcaaaagc ttcaaaagct tcctttacac tgctaattga cacttctggt
     8161 agtgacttgg ctgtcgttag agctgtttga aagagttccc taatctgatc atccactccc
     8221 cacataactt tgggaggtga atcgtgtcca tagcgctcca tgataggaaa gaagagttct
     8281 tccttacgtt ggtaatggat gtcaaattga cccacaagtc ccatctgacg caccaaaccc
     8341 ttacgcatct ccgccagcat ttcctcgtct tccatagact cataggtatc taacaatcta
     8401 cgaatgcgaa tcaaggccgc acggagagcc agattttctt ctttgaagac acgaactggg
     8461 tgacctggat gctcagtatc tgaaacttcg acacctttga tagcattttt aaaaagattg
     8521 gcatggacat cacagagttc cataacatct tcaaaagtga cgcccgaatc cgagttcatc
     8581 agctcgtgct ccataaggga aatctcaatg gctgagacac ccgcaaaggt cgcatcaaaa
     8641 cgctcctgaa ccgactcagg agaggcgcca ttatgcaatt ctaataaaat atcccgtagg
     8701 acatgaatcc gttcatctgc cattagtcta atccaatcac ttcgtagcca ttcgcttcca
     8761 gtgtgcgtac aatcttgtcc ataggagttc ctgctagctt agaaccctgt ttaagtgata
     8821 ctttacgacc aactgtattg cgcattaagg gattggcaag gggtttaaaa cccaactcca
     8881 ctagaatttc caagacttct ggatgcttgt ccaccacttc tgcaacagga attgacacat
     8941 cgatgatatt gtccatgacg acctccatta tatgttctaa tactcaatga aaatcaaaga
     9001 gcaaactagg aagctagccg caggttgctc aaaacagtgc tttgagattg tagatagaac
     9061 tgacgaagtc agtaacatat atacagcaag gtgaagctga cgtggtttga agagattttc
     9121 gaagagtata aaatgatttt actgcttata ttataccata tggaaagaga ataaaaaact
     9181 agcagtggag ttcctgctag ttctctgcga cttggattac catctagata agtttaaaga
     9241 accaatccaa tatcttgtaa aacagcaatt ggactgcaaa agagatgatc atccaaaaga
     9301 atttcacaat cccaataatc ggtttgataa aaataatggc aagaagtccc cagaaaaatt
     9361 tcatttttta tcctctggct taatgagcca ccgagccgta tccattaact tgtcggcaat
     9421 aaaaagtttc cccagaccga caacggcatt atcatctttc tttatcgttt tcattacttt
     9481 tacaccttgc acggtcaaaa agtaattacc ataaatttta gcaaaagctt tgataggatt
     9541 catattactc tcctttgatg atttcagcct cttttcggat tgtttcaaca tcttcttgat
     9601 attgaacttc actatagttg actagcttgg ataattcttt ctgcaagctt tcccccattg
     9661 gtttcatagt tgcaaaggtt aaaccacctg aaatgatacc acccaagata ggaataaatt
     9721 tccccattcc tttggccagc cctcccttgg taagattcac accaaatatt cttaagactt
     9781 tcttcaaaat aggataccaa agcgtctttg ttaaagcttt attaggtact gttttcatta
     9841 cctgtttggc aattgttata ccaccagcac gtagcaaagc agcagttcca ttcaccccca
     9901 acatgacgcc tagataaagc aaaagggtat tttgagcatc ttcactcaac tcatcgcgtg
     9961 aagcccaaag atcctcataa ccataaatat aacctaattc ttgggccaat ttcagagaga
    10021 aaccataaaa ttgagccaca tcagctggaa tggtaattgc catagcaagc cctccaggta
    10081 atcctgccaa aacagaagtc ccactcgcta ataaaacatt atccctaata caggcattag
    10141 ccactcgatc taagatttct tgagataaga gagacgttgg accttgttcc aataaggtag
    10201 gaatgtcctg tggacccaat tctttggaaa acttatccac taaaaatttc gaacgatcaa
    10261 ccttaacaac aggtagtttc accacttgtt gcaatacttg catagctaag tcttgttcag
    10321 ccatatacaa actccttatt tcttttttgc accttatcat attatatttc ctacaaaaaa
    10381 agcattttct aattagataa cattaaaaaa tacagaaccc ctttt
//
LOCUS       DAVBNN010000068         9700 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBNN010000068 DAVBNN010000000
VERSION     DAVBNN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.068"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ847_001820"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ847_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ847_001821"
     CDS             complement(546..1166)
                     /locus_tag="VQ847_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3051117.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ847_001822"
     CDS             complement(1166..1648)
                     /locus_tag="VQ847_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3051118.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ847_001823"
     CDS             complement(1648..2490)
                     /locus_tag="VQ847_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3051119.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ847_001824"
     CDS             complement(2585..3385)
                     /locus_tag="VQ847_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3051120.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ847_001825"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ847_001825"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3051121.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ847_001826"
     CDS             4918..5463
                     /locus_tag="VQ847_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3051122.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ847_001827"
     CDS             5475..5789
                     /locus_tag="VQ847_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3051123.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ847_001828"
     CDS             5806..6498
                     /locus_tag="VQ847_001828"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3051124.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ847_001829"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ847_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3051125.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ847_001830"
     CDS             7140..7730
                     /locus_tag="VQ847_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3051126.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ847_001831"
     CDS             7739..9502
                     /locus_tag="VQ847_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3051127.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3004 a         1686 c         2066 g         2944 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ctgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaaaata gtacacaatg
//
LOCUS       DAVBNN010000069         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBNN010000069 DAVBNN010000000
VERSION     DAVBNN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.069"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ847_001832"
     CDS             complement(358..1965)
                     /locus_tag="VQ847_001832"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3051128.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ847_001833"
     CDS             complement(2355..2942)
                     /locus_tag="VQ847_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3051129.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ847_001834"
     CDS             complement(3070..3519)
                     /locus_tag="VQ847_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3051130.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ847_001835"
     CDS             complement(3524..3913)
                     /locus_tag="VQ847_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3051131.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ847_001836"
     CDS             complement(3941..4567)
                     /locus_tag="VQ847_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3051132.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ847_001837"
     CDS             complement(4581..5144)
                     /locus_tag="VQ847_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3051133.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ847_001838"
     CDS             complement(5597..6100)
                     /locus_tag="VQ847_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3051134.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ847_001839"
     CDS             complement(6293..7123)
                     /locus_tag="VQ847_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3051135.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ847_001840"
     CDS             complement(7108..8790)
                     /locus_tag="VQ847_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3051136.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2722 a         2058 c         1637 g         2577 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttgta aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBNN010000070         8327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBNN010000070 DAVBNN010000000
VERSION     DAVBNN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.070"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(549..857)
                     /locus_tag="VQ847_001841"
     CDS             complement(549..857)
                     /locus_tag="VQ847_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3051137.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VQ847_001842"
     CDS             complement(854..1162)
                     /locus_tag="VQ847_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3051138.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VQ847_001843"
     CDS             complement(1167..2462)
                     /locus_tag="VQ847_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3051139.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VQ847_001844"
     CDS             complement(2480..3889)
                     /locus_tag="VQ847_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3051140.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VQ847_001845"
     CDS             4047..4775
                     /locus_tag="VQ847_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3051141.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VQ847_001846"
     CDS             5234..5428
                     /locus_tag="VQ847_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3051142.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5793..7103)
                     /locus_tag="VQ847_001847"
     CDS             complement(5793..7103)
                     /locus_tag="VQ847_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3051143.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7340..8212
                     /locus_tag="VQ847_001848"
     CDS             7340..8212
                     /locus_tag="VQ847_001848"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3051144.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2589 a         1457 c         1583 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 cgtcatattt ttcatattct tgaatccatc gataaagact attgggatga atttttaaag
     5641 ttgaactaat tatttttaca ggatgaggtt tacagcagag agtttgaagg ctttatcaaa
     5701 ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc tactttatta
     5761 taccaagtcc acccttaagt tagataatga atctaactta aggaagctag aaggatgaga
     5821 atccaggtgg tcaagagtcc caaacttaag ctgataggga cacccagaat aatttgcttt
     5881 ttgaaggcaa gaccgcgttc ctctatattg gggagtgaga gttgaatgag agaaccagct
     5941 gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt tgtgagtaag
     6001 tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa gagggctgga
     6061 gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac acaaaagaac
     6121 agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag tgtgactaaa
     6181 cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat aattgtagcc
     6241 cagggaactt tagccaaaat ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag
     6301 accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc tatccaggcg
     6361 atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat gctgctgatc
     6421 atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag
     6481 gatgagtttg ttcttccctt actatagtgg ctgtaacagg ataataaaag caagacgatg
     6541 agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc ttgctcttcc
     6601 catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt tatcaaatta
     6661 gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg tttgtccgct
     6721 ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa aaatccagca
     6781 cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc gttaggatgg
     6841 gtgcgtgtgc ggtagagaat gtgttgagcc aagacatcaa gagtaccgtt agttgttgca
     6901 acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga
     6961 agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga aaaagcaata
     7021 gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag agcaatggcg
     7081 ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg aaataggttg
     7141 gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa
     7201 aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa tgaggtattc
     7261 aggcttgtga tttcctatgg aagttcatag tgattgcctc tagtgcttac aagtgatatt
     7321 aaaaatagag gatctagtga tgtcaatcat ttcaactgat ttaacccctt ttcaaataga
     7381 tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca gtaccaatgc
     7441 catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt
     7501 agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg tgaccttcca
     7561 gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg ttttagaaat
     7621 cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca
     7681 tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg atgattgcat
     7741 taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga aatatgccgt
     7801 gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc tgctaaaaga
     7861 caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc
     7921 cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg aagaagctgc
     7981 ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga ttgaacaggc
     8041 cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg atatgaccac
     8101 tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt taacccatag
     8161 tgctaagagt cttgattttt ccatgaaggg gttaacctac cttgatgtct aagttgtaaa
     8221 ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc agatagttta
     8281 aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatg
//
LOCUS       DAVBNN010000071         7515 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBNN010000071 DAVBNN010000000
VERSION     DAVBNN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.071"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(110..1960)
                     /locus_tag="VQ847_001849"
     CDS             complement(110..1960)
                     /locus_tag="VQ847_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3051145.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2028..3167)
                     /locus_tag="VQ847_001850"
     CDS             complement(2028..3167)
                     /locus_tag="VQ847_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3051146.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            3225..4391
                     /locus_tag="VQ847_001851"
     CDS             3225..4391
                     /locus_tag="VQ847_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3051147.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            4530..4856
                     /locus_tag="VQ847_001852"
     CDS             4530..4856
                     /locus_tag="VQ847_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3051148.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4843..5436
                     /locus_tag="VQ847_001853"
     CDS             4843..5436
                     /locus_tag="VQ847_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3051149.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            5429..6340
                     /locus_tag="VQ847_001854"
     CDS             5429..6340
                     /locus_tag="VQ847_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3051150.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6403..7467
                     /locus_tag="VQ847_001855"
     CDS             6403..7467
                     /locus_tag="VQ847_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051151.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
BASE COUNT         2282 a         1720 c         1310 g         2203 t
ORIGIN      
        1 caaggtgaaa ctgacgtggt ttgaagagat tttcgaagag tataagtctc tacataataa
       61 aacgcatatt accaaggtta tttaacttga taatatgcgt ttttcttttt tattcaatgt
      121 gggttgtttg attagcaaag gcgataatag cttgcttcaa ctcatctcca ctgagagtgc
      181 ggaactctcc aatcttttga ttgatggatt ctaaaggcat gacattaacc ttaccaacga
      241 aaatcttatc cataacttga ttatcaacga gttcggttga taccaagagt tcttcgtaga
      301 gtttttcacc tgggcggatt ccaacttcaa cgattggaat ttcactttca gtgtggccac
      361 ttagaagcac catcttcttg gccaagtcat aaatcttgac tggtttgccc atatcaagga
      421 taaagacttc cccatctttg gcataagcac cagcatggat aaccagacgg ctagcttctg
      481 gaatggtcat aaagtaacgg gtcatgcgga agtctgtcac cgttacaggc ccaccttcag
      541 caatctgacg ttcaaagact ggaatgacac taccacggct accaagaaca ttcccaaaac
      601 gaactgcaca gtaggttgat tggctacgtt ggttaaagcc agtgacaatc aactccgcca
      661 cgcgcttggt tgctcccata acatttggtg gattgactgc cttatctgtc gaaatcataa
      721 ccatcttagg caccttggct tcatcaacgg ctctagcaac attgtaagtt ccacggatat
      781 tgtttttgaa ggcttctttt ggattgcgct ccatcatagg aacatgcttg tgggctgccg
      841 catgataaac aatagcaggt ttgtactgct caaagacttg caacaaacga tcatagtctt
      901 gaatgtccgc aatcacaggt acataatcaa tcccttggaa cttacgaatc aattcatgat
      961 aaacaaggta gattgagttt tccccatgac cgagcaagac aatgcgttca ggattgaagc
     1021 gactaacttg acgacagatt tcagaaccga ttgaacctcc agctcctgtg actaagatgg
     1081 tcttacctgt cagttctgca cccagacgcg attcgtcaag acggatttcc tgacgaccca
     1141 aaaggtccgt aatatcaatt ttttggaagc cagtacctgc ttggtgaagg ccctgaacaa
     1201 cagtttcaac cttaggcatc ttgtaacatt tgacacccag cttattacac atctgcaaga
     1261 tacgctcata ttctgacgga tccagcgacg gaatcgcaac gatgacacgc tcgatttgat
     1321 ggcgtttggc taattcaggc agattgtcat aagagcccaa aacaggaata ccaccaagtt
     1381 tttgaccctt tttcttagaa tccttatcca aaataccgac cagttctaat tcactggttg
     1441 gatgttggta actatccata aagagagccc caccatcacc ggcaccaatc aagaaggtcc
     1501 gacggtgttc tccatcacca ctaccttttt tgcgtctgga gtagattaac tgccaagtaa
     1561 tccgtggcaa taaaatcaag aaggcactca acaagataaa gagaatgata aaacggatgg
     1621 agaagagtgg caagaaggca taacagatac tatatgacaa gacactgcta gcagtcacac
     1681 caaaaaagat tttcatgaaa tccgtaatct tgctgtaacg actaatactc gcgctcaagc
     1741 cccaaaaatc aaccatcaat tgatagaaca ggaaggccaa actcgtatag ataatgtagt
     1801 caacaggtgc tggattaatc agcccataaa ataaaatata agatacaatg atggaaacca
     1861 ccatactgaa aatatcaaat attccccaga aaacctgctt ttgttgttta tttaaaattt
     1921 ccaccagatc aatcacataa tctgtgagtt ttttattcat agaaatttac tcctccttaa
     1981 aatagttcta ctatattgtt attatagcac attttaattt atttggctta tttttccaaa
     2041 taaattactg ttcccttgta ctccttcttc catttaaatc ctctaattaa acctacaatc
     2101 gtcccaaggc cataagcaaa gtgaatggaa aataaaagaa agggcatcac aattagaaat
     2161 ccatttttat gttttaataa agtcagcaaa gtgagtaatg acagtaatga taaaagtaga
     2221 aaataggcac ctaatagtaa agttatgaat acgaatgtga tcggtaacaa tgctagacta
     2281 aacacaagac tcaaaacaaa taaacaagga acataatgaa ataatgataa acacttaaac
     2341 tgaacatgac ttgtcaagcc aatccacaaa ccatttgaat acttttgatg cagcattttc
     2401 ttgaatgttg gtcgaatata ctgataagat agaatacttg ggctatagcg gattttataa
     2461 ccatgttctc gaattctata atgaatatca ttatcttcag ttcggccaag ttgctcattt
     2521 actaaaccaa ccttctggaa aacctctcgt ttatacatcc catgaaaaat agaagaaaca
     2581 tatctatcct cggaactatt tcgataattg gcaatgctac tgccaaacat attttcctca
     2641 acaagatgca aggtctctgc ccattttcct tttcctttga caatcgtcgg tctaggccct
     2701 ccacagacaa attcaccttg ttgaataaca gccacattgt tcattacaaa actctcagta
     2761 acttttgaat gagcatcaat ttttaaaata aggcccccta cagaatgctt aactcccagg
     2821 ttaaaaccac tagcttgatt tttcttagga ttgttataca atctaattga gttaaactct
     2881 gcatcttctt ttataaattg ctgaatgata gctgtggtcc catctgtgga catagcattt
     2941 ataaatagaa tttcaatatt ctctttagga taggtttgat tttttaagtc ttcaattaga
     3001 ccaggcagat atttttcttc attgtatgca ctgattacaa tggatacgag aagactttca
     3061 acattttgag tcactactac tctcctgaat tttcccttcc accattctat cataattttc
     3121 aagacttttc catttttatc ttgaaagcca gaaaccttac ttgacattat agtgaaaaag
     3181 ccttaaaata agctgttatt aaaatcagct agaagagata ttatatgaaa aagcaatcac
     3241 tcttttttgt tccaggtatt atcctgattg gtgtttcctt gcgaactcct tttactgttt
     3301 tacccattat tttgggaaat atttcgcaag gtctggaggt agaagttagt tcgcttggtg
     3361 tcttgaccag cctgcctctc cttatgttta ccctcttttc accattttct acccgactgg
     3421 ctcagaaaat cggcttggag catctcttca cctacagcct cttcttcttg accatcggct
     3481 cacttattcg actaatcaat ctgcccctgc tctatctagg aaccttgatg gttggggcaa
     3541 gtgtcgcagt catcaatgtc ctgcttccta gtcttatcca agccaatcaa ccaaagaaaa
     3601 ttggttttct gaccacctta tatgtaacgt ctatggggat tgcaacggct ctggcttcct
     3661 atctagctgt gcccattaca caagccagtt cttggaaagg acttatcctc ctcctcacgt
     3721 tactctgtct agcaactttt ttggtctggc tcccaaatca ccgctataat catagactag
     3781 ctccacaaac caaacaaaaa agtcaaataa aggtcatgcg taataaacag gtttgggcaa
     3841 ttattatctt ttcaggtttt caatccttga tcttttacac cgccatgacc tggttaccta
     3901 ccatgtctat ccatgcaggt ctatccagtc acgaagctgg cttgctgact tctatcttat
     3961 ctctgattag cattcctttt tcaatgacca tcccaagcct gacaaccagt ttatctactc
     4021 gcaaccgtca gctcatgctc actctggttt cactagctgg tgtggtcggc atttccatgc
     4081 tctttttccc aatcaataat ttcatttact ggcttgccat ccatctcctc atcggaaccg
     4141 caaccagcgc cctcttccct tatctcatgg tcaacttttc actcaagaca agcgcccctg
     4201 aaaagacagc ccaattgtcc ggcctatctc aaacaggagg ctatatccta gcagcctttg
     4261 ggccaaccct ctttggttac agttttgacc tattccactc ttgggtacca gctgtagctg
     4321 ccctcttgct catcgatatc ctgatgactg tggccctctt tacagtggac agagcggata
     4381 agatccttta aacttctagt tttagctaga agttttttat atataaaaat tttacacatt
     4441 tctcttgaca gggctttctt ttagatgtac aatgtatgtg tagaaaaatt atatataaaa
     4501 atcttacaca ttagaaaagg aggtttccca tgtactttcc aacatcctct gccttgattg
     4561 aatttctcat cttggccgta ctggagcagg gtgattctta tggttatgag attagccaaa
     4621 ccattaagct gatcgctaat atcaaagaat ccacactcta tcccattctc aaaaaattgg
     4681 aaggcaatag ctttctgaca acctattcta gagagttcca aggtcgcatg cgcaaatact
     4741 actccttgac aaacggtggt atagagcagc tcttgaccct aaaagatgaa tgggcactct
     4801 atacagacac catcaatggc atcatagaag ggagtatccg ccatgacaag aactgaatac
     4861 ctgactcagc tagaactcta tctcaagaaa ctacctgaag ctgaccgtat cgaagccatg
     4921 gactatttca gagagctctt tgacgatgct ggagtcgaag gagaagaaga actcatcgct
     4981 agtttgggaa ctcccaaaga agcggcccac gaagttctat ccaatcttct cgataaaaaa
     5041 atcaatgaag cacccgctca aaaaaataac cgacaaattt tacatatcgc cttgttagcc
     5101 ctccttgcag cacctatcgg cattcctctg ggaatcgcca tcctcgtgac cctgttcgca
     5161 atccttgtag ccgctttgac tgtcattctg gctttctttg cagtttccat actgggtatc
     5221 atcggcggat tcctattttt agttgaaagt ttcactgtcc tcgcccaagc caaatcagcc
     5281 tttatcttga tttttggttc tggtttactg gctatcggtg cttcttcgct agttttacta
     5341 ggcatttcct atgtagctcg cttcttcggt ctactcattg ttcgcctggt acaatttgtt
     5401 cttaaaaaaa gaaagagagg taaccagcat gcgtaaatgg acaaaaggat ttctcatctt
     5461 tggtgtggtg actaccgtta tcggctttat ccttcttttt gtaggtatcc aatctgacgg
     5521 gattaaaagc ctactttcca tgtccaaaga acctatctat gatagccgta cggaaaagct
     5581 aacctttggc aaggaagtcg aaaacctaga aattactctc caccaacacg cgctcaccat
     5641 cacagactct ttcgatgatc aaatccacat ttcttaccat ccatctcttt ctgctcacca
     5701 tgatcttatc accaatcaga acgatagaac tctgagtctc actgataaga aactgtctga
     5761 aactccgttt ctctcttctg gaattggtgg gattcttcat atcgcaagta gctactctag
     5821 tcgttttgaa gaagttattc tccagctacc aaaagggaga actctaaaag ggatcaacat
     5881 ctcagccaat cgcggacaaa ccaccatcat aaatgctagc cttgaaaatg cgaccctcaa
     5941 tacaaacagc tatatcctcc gaattgaagg aagtcgtatc aaaaacagta aactcacaac
     6001 gcccaatatc gttaatatct ttgatacagt tcttacagat agtcagctag agtcaacaga
     6061 gaatcacttc cacgctgaaa atatccaagt ccatggcaag gttgaactga ctgccaaaga
     6121 ttatctcaga atcatcctaa accagaaaga aagccaacga attaactggg acatctcaag
     6181 caactatggt tctatcttcc aattcacaag agaaaagcct gaatcaagag gtacggaatt
     6241 aagcaaccct tacaaaactg aaaaaaccga tgtcaaggat caactcattg cgagatctga
     6301 tgataatatt gatctaatat ccacaccaag cagacgttga caaaaacgct tacatctgct
     6361 actatggaag catatttatc taactaaaaa ggaggttcta ccatgaaaca agaatggttt
     6421 gaaagtaatg attttgtaaa aacaacaagc aagaacaagc ctgaagagca agctcaagag
     6481 gttgcagaca aggctgaaga aacgatagcc gatctcgata caccaattga aaaaaatact
     6541 cagttagagg aggaagtccc tcaagctgaa gtcgaattgg aaagccagca agaagagaaa
     6601 attgaagctc ctgaagacag tgaagcgaga acagaaatag aagaaaagaa ggcatctaat
     6661 tctactgaag aagagccaga cctttctaaa gaaacagaaa aagtcactat agctgaagag
     6721 agccaagaag ctcttcctca gcaaaaagca accacgaaag agccacttct tatcagtaaa
     6781 tctttagaaa gtccttatat ccccgaccaa gctccaaaat ctagggataa atggaaagag
     6841 caagtgcttg atttttggtc ttggctagtg gaagcgatca aatctcctac aagtaagttg
     6901 gaaacaagta tcacacacag ttacacagcc tttctcttgc tcattctgtt ttctgcatct
     6961 tcctttttct ttagtatcta tcacatcaaa catgcttact atggacatat agcaagcatt
     7021 aacagtcgct tccctgagca gctagctcct ttaactcttt tttctatcat ctctatccta
     7081 gtagcgacaa cactcttctt cttttcattc ctcttgggta gtttcgttgt gagacgattt
     7141 atccaccagg aaaaggactg gacgctagac aaggttctcc aacaatatag tcaactctta
     7201 gcaattccaa tcttcctcac tgctattgct agtttctttg ctttctttga tagcctacga
     7261 tttacagccc tcttgtgtgt gattagcatt ggaatcattc tgcttgccag tctccatatc
     7321 attacaagac caagtcaagc aagtgaaacc gactccttct atcaattatt cttgtctgtc
     7381 cttgtgaacg gagttattat cctcctcttc tttgtagctg aagtggcact gattggagat
     7441 tatcttcgta tcttggcctt tctttaaact tcatactctt cgaaaatcaa attcaaacca
     7501 cgtcagcttc gcctt
//
LOCUS       DAVBNN010000072         7483 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBNN010000072 DAVBNN010000000
VERSION     DAVBNN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.072"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            156..311
                     /locus_tag="VQ847_001856"
                     /pseudo
     CDS             156..311
                     /locus_tag="VQ847_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            511..3786
                     /gene="rexB"
                     /locus_tag="VQ847_001857"
     CDS             511..3786
                     /gene="rexB"
                     /locus_tag="VQ847_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3051152.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3783..7433
                     /gene="addA"
                     /locus_tag="VQ847_001858"
     CDS             3783..7433
                     /gene="addA"
                     /locus_tag="VQ847_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3051153.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2276 a         1573 c         1593 g         2041 t
ORIGIN      
        1 cattgtgtac tatttttggt tcattttact atagtagatt gaaataagat acgaacagct
       61 tgattaggga aatcaaatta atttctagaa atattttagc atccacggtg tactattata
      121 gtttcaattt actatagttc aatcattcta tcaagaatat tgaatatata aaggcacgta
      181 atattaaaac ttcttctgat atcgaattag agtccgatgt tgatggcgat aaatcagaca
      241 atctaccagt cgacattaag atactgggac aacacattga agtgtattcc gtacctaaga
      301 aacaatcata aaactcaaag ccttgttacc gaggcttttt tattatgtga ttttcagtag
      361 ccagacttat tctatctaat acaagtaaag ctaagtattt aagatttagc agatgatgaa
      421 gaaaagaaag gatggcctaa atattttaac agatttacga ggctaatcat ggtataatat
      481 agggtgatga aaaattccaa cgaggctgag atgaaattac tttatactga tattcggact
      541 tctttgacag aaattctaac aagagaggca gaagagctag ttgcagctgg caagcgggtc
      601 ttctacattg cccccaactc tctttctttt gaaaaggaac gcgccgtgct ggaatgcttg
      661 tcccagcagg cttctttttc gattaccgtc acgcgctttg ctcaaatggc tcgttatctg
      721 gtcttgaatg atttaccagc taaaactact cttgatgata tcggtcttgg gttggccttt
      781 tacaaatgcc ttgccgaact cgatcccaag gacttgcgtg tttatggcgc tattaagcag
      841 gatcctcaat tgatccagca gttaattgag ctttaccatg agatgaccaa atcccagatg
      901 agttttttgg acttggagaa tttaacagat gaggataaga gggcggattt actcttgatt
      961 tttgagaaag taacagccta tcttaatcaa ggtcagttag cccagggaag tcagttgtcc
     1021 catttgattg aggctattga gaatgacaag gtaagtagtg attttaatca aatcaccttg
     1081 gtcattgacg gctttactcg tttttctgct gaggaagagc gggttgtgga cttacttcac
     1141 ggcaaaggtg ttgagattgt tatcggggct tatgctagta agaaagccta taccagtcct
     1201 tttagcgagg gcaatctcta ccaagccagc gtaaaatttc tccatcatct ggcttctaaa
     1261 taccaaacgc ctgctcagga ctgttctcaa actcatgaga agatggatag ttttgacaag
     1321 gcctctcgtt tgttggagtc ttcttatgac ttttcagaac tcgctttgga tgtcgatgag
     1381 aaagaccgtg aaaatttaca aatctggtct tgtttgacgc aaaaggagga gttggagcta
     1441 gtagcccgta gtattcgtca gaaattacat gagaactcag acctgagcta caagcatttt
     1501 cgtattctct tgggggatgt agcttcttac cagttatctc tcaaaaccat ttttgaccag
     1561 tatcagattc ctttttatct tggtagaagc gaagccatgg ctcatcatcc cttgactcag
     1621 tttgtcgagt ctattttagc tttaaaacgt taccgttttc gtcaggagga tttgattaat
     1681 cttcttagaa ctgatttgta tactgacctc agtcagtctg atattgatgc ttttgagcaa
     1741 tatatccgct atcttggtat caatggcttg ccagcctttc agcaaatctt caccaaatcc
     1801 caccatggaa aatttaatct tgagcgtttg aatgtcctcc gcctgagaat tttagcacct
     1861 cttgaaaccc tctttgccag ccgaaaacaa aaggctgaaa acctcctaca aaaatggagt
     1921 gtctttctaa aagaaggagc tgtgaccaag cagttacaag atttgacaac cactttggaa
     1981 gctgtagaac aggaaagaca agccgaagtt tggaaggctt tctgccatgt tttagaacaa
     2041 tttgcgactg tttttgctgg ttcacaggtt agtctggaag acttcctagc cttgctccat
     2101 tctggaatga gtttgtccca ataccgtacc attccagcaa cagtggacac tgttctggtg
     2161 cagagttacg atttgattgc accattgact gctgactttg tctatgctat tggactaact
     2221 caggacaatt taccaaaaat ttctcaaaac accagtcttc tgacagatga agaaaggcaa
     2281 aacctaaacc aagcgaccga agaaggcgtt caattactga ttgccagcag tgaaaatctc
     2341 aagaaaaatc gctacactat gctttccttg gtcaattctg ctcgtaagca gttgttcttg
     2401 tcggctccaa gcctttttaa cgaaagtgaa agtaaggaat ctgcctatct tcaagagttg
     2461 atccattttg gatttaggcg gagagagaag aggatgaatc acaaaggact gtctaaggag
     2521 gatatggggt cctatcacag tcttttgtct agtctggttg cctatcacca gcagggtgag
     2581 atgagcgata ctgagcaaga tttgactttt gtcaaggttc tgtcgcgtgt cataggtaaa
     2641 aaactagatc tgcaaggtct ggaaaatcca gctatcccaa ccagtccaag cagcaagacc
     2701 ttagccaagg acaccttgca agctctctat cctgccaaac aggagtttta cctgtctacg
     2761 tcgggtttga cagagtttta tcgcaatgaa tacagttatt tcctacgcta cgttttaggc
     2821 ttgcaggagg aattacgttt gcgtcctgat gcccgtagtc acgggaattt cttgcatcgt
     2881 atctttgaac gcgccttaca gttgcctaat gaagattcct ttgaccaacg tctagaacaa
     2941 gctattcaag aaaccagtca agaacgcgaa tttgaagcta tttatcaaga aagtttggaa
     3001 gcccagttta ccaaggaagt tttgcttgat gttgcacgga cgactggaca tattctccga
     3061 cacaatccag ccatcgaaac tatcaaagaa gaagcaaatt ttggtggaaa agaccaagcc
     3121 tttattcaat tagacaatgg acgcagtgtc tttgtacgag gcaaggtgga ccggattgac
     3181 cgtttgaaag ctaatggagc gataggagta gtagactaca aatccagtct gactcagttc
     3241 cagtttcctc atttctttaa tgggctcaat tctcagttac caacctatct tgctgcccta
     3301 aaaagagaag ggaagcagaa ctttttcggc gccatgtact tggaaatggc tgaacctgtc
     3361 caatctctga tggcggtaaa aagtctggca ggagcagtgg tagaagccag caaatctatg
     3421 aaataccaag ggctcttctt ggaaaaagaa agcagttatt taggcgaatt ttataacaaa
     3481 aacaaggcta atcaactgac agatgaggaa tttcagctcc tactggacta caatgcctat
     3541 ctttacaaga aagctgctga gaagatttta gcaggccggt tcgccatcaa tccttatact
     3601 gaaaatggca gaagcattgc cccatacgtc cagcaacatc aggctattac aggctttgaa
     3661 gccaattacc atctgggcca agcccgtttc ctagaaaaat tggacctagc tgatggcaag
     3721 cgtctggtcg gagaaaaact caagcaagct tggtttgaaa aaataagaga ggagttaaat
     3781 cgatgaagct tattcccttt ttaagtgagg aggagattca aaaactgcaa gaagcagaag
     3841 caaattcgag caaggaacag aagaaaactg ccgaacaaat cgaagctatc tacacttctg
     3901 gtcagaatat cctggtctca gcatcggctg gttctggaaa gacctttgtc atggcagagc
     3961 gcattctgga ccaattggcg cgtggtgtcg aaatttctca actctttatc tcaaccttta
     4021 ccgtcaaggc tgcaactgaa cttaaagaac gtttagagaa aaaaatcagc aagaaaatcc
     4081 aagaaacaga tgatgtcgat ctcaaacaac acttgggtcg ccagttggca gacctaccca
     4141 acgctgccat cggaaccatg gactctttca cacaaaaatt ccttggcaaa catggttatc
     4201 tgcttgatat tgcacctaat ttccgtattt tacaaaacca aagcgagcaa cttcttctcg
     4261 aaaacgaagt ctttcatgag gtctttgaag cgcattacca aggtaaacag aaagagagct
     4321 ttagtcattt gctgaaaaac tttgctgggc gtggcaagga cgaacggggt ctgcggcagc
     4381 aagtctataa aatctatgac ttcctccaat ccaccagtaa tcctcaaaag tggctgagtg
     4441 aatctttcct caaaggcttt gagaaagctg attttaccag tgaaaaagaa aaactgactg
     4501 agcaaatcaa acaagccctc tgggatttgg aaagattttt ccgttaccat ctggataacg
     4561 atgccaagga gtttgcaaag gctgcctatt tagaaaatgt tcagttaatt ctggatgaaa
     4621 ttggctccct aaatcaggag ttcgatagtc aggcttatca ggcagtactt gcgcgtgttg
     4681 tcgccatctc taaggagaaa aacggtcgtg ctctgactaa tgccagccgt aaggctgatt
     4741 tgaagcccct ggctgatgcc tacaacgaag agagaaagac ccagtttact aaactaggac
     4801 aattatcaga ccagatagcg attctcgact atcaagaacg ttatcatgga gacacttgga
     4861 aactagctaa aaccttccaa tctttcatga gcgattttgt agaggcttat cgtcagagaa
     4921 aacgacagga aaatgccttt gaattcgctg atatcagcca ttacaccatt gagattttag
     4981 aaaatttccc acaagttcgt gagtcttatc aggagcgctt ccatgaagtc atggtcgatg
     5041 agtatcagga taccaaccat attcaagaac ggatgctgga attgttgtct aatggccaca
     5101 atcgctttat ggtgggagat atcaagcaat ccatctatcg tttccgtcag gcagacccgc
     5161 agattttcaa tgagaaattc caacgctatg cgcaaaatcc ccaagaaggc aagctcattc
     5221 tcctcaagga aaatttccgt agtagttcag aagtgctgtc agcaaccaat gatgtctttg
     5281 aacgtctcat ggaccaagag gtcggcgaaa tcaactatga taacaagcac cagcttgttt
     5341 ttgccaatac caaactgact cccaatccag acaacaaggc agaatttctc ctctacgaca
     5401 aggacgatac aggtgaggaa gaagagagtc aaacagaaac gaaactaaca ggcgaaatgc
     5461 gcttagttat caaggagatt ctgaaacttc atcaagaaaa aggtgttgcc tttaaggaaa
     5521 ttgcccttct gacctccagc cgcagtcgta atgaccagat tctcctcgcc ctgtctgagt
     5581 acgggattcc tgtcaaaact gacggagagc aaaacaatta tctccaatcc ctagaagtgc
     5641 aagtcatgct agacactctt cgtgtcattc acaatcccct gcaagactat gccttggttg
     5701 cccttatgaa gtctccaatg tttggttttg atgaggatga gctagcacgt ttgtcccttc
     5761 agaaagcaga ggataaagtc cacgaaaatc tctatgagaa actggtcaat gcacaaaaaa
     5821 tggcaagtag tcaaaaaggc ttgattcaca cagctctagc tgaaaaacta aagcaattca
     5881 tggatatcct agcttcttgg cgcttgtatg ccaaaaccca ctctctctat gacttgattt
     5941 ggaagattta caacgaccgt ttttattatg actatgttgg ggctttgccg aatggtcctg
     6001 ctaggcaggc caatctctat gccctagcac tgcgtgctga tcaatttgaa aagagcaatt
     6061 tcaaaggttt gtcgcgtttt attcgtatga ttgaccaagt cttagaagcc cagcacgatt
     6121 tgtcaagcgt ggccgtcgca ccgccaaaag atgcagtaga gctcatgacc atccacaaga
     6181 gtaaagggct ggagtttcct tacgtcttta tcctcaatat ggatcaagat ttcaacaagc
     6241 aagactctat gtcagaagtc attctcagtc gtcagaatgg tcttggtgtc aaatatattg
     6301 ccaagatgga gacaggggca gtagaagacc actatcctaa aaccatcaaa ctctccattc
     6361 ctagtctgac ctataggcag aacgaagagg aattacagct agcaagctat tctgagcaga
     6421 tgcgtttgct gtatgttgct atgacgcggg ctgagaaaaa gctctatctt gtcggcaagg
     6481 gttctcgtga aaagctggaa gtcaagcaat acccagcagc caaaaatggg aaactaaata
     6541 gcaatactag actgcaagca cggaatttcc aagattggct ttgggctatc agtaaagtgt
     6601 ttactaagga caagctcaac tttagttatc gttttattgg cgaagatcag ttgaccagag
     6661 aagctatcgg agagttggaa accaagagtc ctctccaaga tagctcccaa gcagacaatc
     6721 gtcagtcaga taccatcaaa gaagctctgg aaatgctgaa ggaggtggaa gtttataata
     6781 ctcttcaccg cgcagctatt gaacttccta gtgttcaaac cccaagtcaa atcaagaaat
     6841 tctacgaacc agttatggat atggaaggtg tcgagattgc tggtcaaggt cagtcagtag
     6901 gcaagaaaat cagcttcgat ttgccagatt tttcaaccaa agaaaaggta actggagctg
     6961 agattggtag tgctactcac gaactcatgc agagaattga cctcagccag caactaaccc
     7021 ttgctagcct aacagaaaca ctcaaacaag ttcaaactag ccaagctgtc agagacaaga
     7081 tcaatcttga taaaattctt gctttctttg acacagtact cggtcaggaa attcttgcta
     7141 ataccgacca tctctatcgc gagcaacctt tctccatgct caaacgagac caaaagagtc
     7201 aggaagactt tgttgtccgt ggtatccttg atggctatct gctttacgaa aacaaaattg
     7261 ttctgttcga ctacaagaca gaccgctatg atgaaccaag tcaactcgta gaccgctatc
     7321 gtggtcagtt agctctatac gaagaggctt tatcacgagc ctattcgatt gaaaatattg
     7381 aaaaatactt gattttactc ggtaaagacg aggttcaagt tgtaaaagta taacttatac
     7441 tctttgaaaa tctcttcaaa ccacgtcagc ttcgccttgc tgt
//
LOCUS       DAVBNN010000073         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBNN010000073 DAVBNN010000000
VERSION     DAVBNN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.073"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            52..693
                     /locus_tag="VQ847_001859"
     CDS             52..693
                     /locus_tag="VQ847_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3051154.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(735..2723)
                     /locus_tag="VQ847_001860"
     CDS             complement(735..2723)
                     /locus_tag="VQ847_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3051155.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="VQ847_001861"
     CDS             complement(2725..3483)
                     /locus_tag="VQ847_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3051156.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="VQ847_001862"
     CDS             3911..4102
                     /locus_tag="VQ847_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051157.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4456..4728)
                     /locus_tag="VQ847_001863"
     CDS             complement(4456..4728)
                     /locus_tag="VQ847_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3051158.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4787..5236)
                     /locus_tag="VQ847_001864"
     CDS             complement(4787..5236)
                     /locus_tag="VQ847_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3051159.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            complement(5223..7352)
                     /locus_tag="VQ847_001865"
     CDS             complement(5223..7352)
                     /locus_tag="VQ847_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3051160.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2210 a         1562 c         1472 g         2230 t
ORIGIN      
        1 tcagaaacaa atcacgaaat cgattcaaat tttgcaggtc gtttaaatat cctgcgcgca
       61 ggtgttcttg gtgctaacga tggaattatt tccattgctg gtgtggttat cggggttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggat ttgcggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgtta gaccaagata gggaactagc caaaaaatcc
      301 ctcgatgctg cttatatcca aaatggagaa tgcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctact
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca ctagtgccag acttggaaag
      601 gatccgacta gaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg
      961 gtttgcttga tttgcttttg gtccaaacca actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttcacaat gaaatcttta ttaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gattcgcaac agcaaagtaa gtgtaacgaa gcacttcttt ctctttaatc
     1681 ttataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagga ttctgcggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa aatagcgata
     1861 gttgctagtc caactgcatt tttcttcata cggaaaatca agttagaaac agatatgaga
     1921 ttattaggtt ggtaatagta tttcttattt ttctttaaga tttgaaggaa aacggtaatc
     1981 cctgcattga acaaaagata agtaccaaag ataaccagta aaacagctat gaagaaggtt
     2041 gttaaggctg taagaggatc ttttaccgta agggcaagat aatatccaat ccctaaactt
     2101 atggaaccaa gaatagtttg gagaggaagg aagcgacctt ttttctctcc gctagctttc
     2161 tcacgtgaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaaaccgaa gacaagaagt actgtaatga caactttcat ctggaaggta
     2281 gcgaccagtt ccaccttcaa tttcatcagt ttgagtagga aagcgaaaat caacttgtca
     2341 aacaaggctc caataccgat tcctgctcca acagttagaa tcccaaatag cactaactcc
     2401 ttaaaggtca tactgattag atggcgcttc tccaagccta acatgccata tatacccagt
     2461 tccttggaac ggtttttcat gacaaaacta ttggcataga ggacgataat ggctgacgca
     2521 agggtaacga caaacatacc aaatccaagt gttgcttgaa tggtggttcc tccacggatt
     2581 tccgcaatct ttggattgaa ggttagggag taaaagagat aggtgatggt gactgccaag
     2641 agaacagcca gtgcaaaggg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaag
     2821 aatgccgtct ttgataaaga gaacacgctt ggccctgcta gcagctgctg ttgagtgggt
     2881 taccatgagg atggtttgcc cacgctcatt gatttcatta aagacatcaa gtaaggctgc
     2941 agatgacttg gaatcaaggg ctcctgttgg ctcgtccgca aggagaattt caggttctgt
     3001 gatgatggcg cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta
     3061 cttctcttgc aattggttga tacccagatt ttcagctgtc atcaccaatt tcttcatcat
     3121 ctccgttata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgctgtatc agttccgttt aggtaaacct gcccacgact
     3301 tggtttatcc agcatagcta ggatattgag cagagtggat ttaccagaac cagactcacc
     3361 catgatagca acgtagtcac ccttttctac ggtgaagtga atatccttga gggcctctac
     3421 ttggttgccc tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgagaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtgtgaaa aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaaggtta
     3841 cctagataac ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc ggtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcag cagcaaaaat agattaaaaa actgagttta aattactgct tttataataa
     4141 aatgaaataa gaacaggaca aatcgatcag gatagtcaaa tcgatttcta acaatgtttt
     4201 agaagtagag gtgtactatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat gtcaacttca cattgccgac
     4321 taaattacag cctgtggctg gcttcctagt ttgcactttg atttttattg agtataaaag
     4381 taaaaaagct ttaaatcaag cagtttagac tattgattta aagatttttg cttattccaa
     4441 atcttctgta gaacctcacc aaaaccagcc ttcattgtcg tcaatggctt gggcttcttt
     4501 gcgtttacgt gggcctgttc cgtacatttc tgcttcgatt tcttccttgg taggcatgat
     4561 agaagctagg atgatataga taatcacgcc aagtccaaag tttgcaactg taaaaatggc
     4621 aaacaagaaa cgaactaggg taacatcaaa attccacttg tctgacagac ctgccagaac
     4681 tcctgaaatc atgcgattgc gtctcatttt ataaaattta ctgttcatga tatttcctct
     4741 ttctgctagg ttagacatag tatatcacgg ggaggctcgg ctttcatcag tcctcaggct
     4801 gatttatcag aagcaattta cctcgacaaa gtccacagcg atagcgttgg gtatcaatcc
     4861 tacgcttgcg ctgatacctt tgctggcagg attgacaacg ataaagcttg agtggtttag
     4921 agttactatt gggcaaggat ggtacaaacc ttaatccatc cactgctttc aaaagttcct
     4981 taaaatcccg atccttgtgt tgatagccct tcccttggaa ataaaggtga taatgacaga
     5041 gttcatgtcg gacaattttc ctaaaaacct ccatacccag tttctgataa accttgggat
     5101 taaaatccag atgcccatct ttggggaaaa atcgcccacc tgtcgaacgt agacgcctat
     5161 tccactggac atgatggata aaagctctcc cgaagtcttc tagtgaaacc tgcttgacat
     5221 aatcagtcag tttcatttgg agcgaggagc gacagattaa ctttttcacg ttcagtatca
     5281 attttcttga cccaaacggt caccaaatct ccaactgaca ccacttgact agggtgtttg
     5341 ataaacttgc gactcatatg agaaatatga atcaagccgt cctcgtgaat cccgatatca
     5401 acgaaggcac cgaagtcaac aacgttacgc acaacacctt ctagcttctg acctaccact
     5461 aggtctttga tatctaggac atcttggcga agcacaggtg cgtcaaagga atcacggaaa
     5521 tctcgacctg gtttgagaag atctgcaatg atatctttaa gggtttctgg accgaggtct
     5581 agctcttgag ccatttcctt gactgaaagg gacttgagtt tgctttgggc ttcttcgttt
     5641 aggtctttaa tatctaaacg tttgaagagt tccttaactg cagtgtaatt ctctgggtga
     5701 actcctgtat tatcaaggat attgctactt tcagggatac gaaggaaacc agcagcctgc
     5761 tcaaaggcct tggctcccag acgaggaact ttcttgattt gggcgcgtga agtgattttt
     5821 ccttcttcct cgcggtattt gacaatattt tcagagatag ttttgttgag tccagctacg
     5881 tgtgaaagaa gagctgggct agctgtattg acattgacac caacttggtt aaccactgta
     5941 tcgacaacaa agtccagact ctcagatagt ttcttctgac tgacatcgtg ttggtattga
     6001 ccgacaccaa ttgacttagg atcgattttg accaattccg caagaggatc ttgcaaacga
     6061 cgggcgatag aaatggcaga gcgtttttca acggtcaagt ctggaaactc ctgacgagca
     6121 agttcgctgg cagaatagac agaagcacca ctttcattaa cgataacata gctgacttca
     6181 gggaaatctt tcagaacttc cgctacaaaa gcttcacttt cacgactggc cgttccattt
     6241 ccaatggcaa taatctctac accgtattga ccaattaaat ctgctaaatc tttcttggct
     6301 tcttcgattt gacgagctga tgctggttta acaggataaa taacctgagt tgtcagcatt
     6361 tttcctgttg catccacgac agctaacttg gcacctgtac gaaaggctgg gtcaaatcca
     6421 agaaccacgc gccctttcag tggagcaacc aagaggagat tgcgcagatt gtcagaaaaa
     6481 agttggatag ctccttcttc agctttctca gttaattctg tccgaatacg acgctcgata
     6541 gcaggcaaga cctttttctt aacggattgc tgaacaactt catcaatata agcatttttc
     6601 accttgaaac gagtagcaaa gaaggcaaga atacggtccg tcgcatgttc aaaaccgatc
     6661 ttcaagacac caagtttctc cccacgattg agagccaagg tacgatagcc ttgcatagtt
     6721 ccaactgtct ctgaaaaatc ataataaatc tgaaaaacct gcttttcatc aagactttca
     6781 tccttggctt gagaagtgag tttagagtgt ctcagcactt cctgataagt catagaacgc
     6841 aaggtcacat cttccgataa ggcttcgacc aaaatatcaa ctgcaccggt caaggcttcc
     6901 ttgccagtcg caaatccttc acagacgaac ttttcagctt ctttctctaa gtcaactata
     6961 ttctgcaaaa tcaagcgagc aagaggaaag agtccagctt cacgggcaat ggttgccttg
     7021 gtacgacgct tttccttata aggaagatag agttcttcaa cgtctgctaa tttttcggca
     7081 actaagatag cttcttccaa ttccttggtc aacttacctt gttcttgaat cttagctaag
     7141 acagcttcct tacggtcatt gagatttgtc agacttttat ccaaatcaat aatagcctta
     7201 atcgccacct catccagact accagtcatg tccttgcgat aacgcgcgat aaagggaata
     7261 gtcgcccctt cagctgtcaa acttagaacg gtatcaattt gctttaacgt cactcccaaa
     7321 tcctgagaga ttttttcata ttttttatcc ataaatctat tataccacaa gctggaaggc
     7381 tttctccaat ccttttcata ctcaataaaa atcaaaaagc aaactaggaa gctagccgta
     7441 ggctgctcaa aatactgttt tgaggttgtg gata
//
LOCUS       DAVBNN010000074         7457 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBNN010000074 DAVBNN010000000
VERSION     DAVBNN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.074"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(173..1588)
                     /locus_tag="VQ847_001866"
     CDS             complement(173..1588)
                     /locus_tag="VQ847_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3051161.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VQ847_001867"
     CDS             complement(1601..3439)
                     /locus_tag="VQ847_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3051162.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4296)
                     /locus_tag="VQ847_001868"
     CDS             complement(3457..4296)
                     /locus_tag="VQ847_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3051163.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..7276)
                     /locus_tag="VQ847_001869"
                     /pseudo
     CDS             complement(4597..7276)
                     /locus_tag="VQ847_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         2446 a         1570 c         1025 g         2416 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggtacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacat catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tatcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctagg ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc cagtttttct
     4201 tccaaaagct attccccttc caaaaagaag aatatcgata tcttttttac tttgcgcaat
     4261 tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt aaaataaaag
     4321 gaacctactt aaaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagtcatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatat aacaagcctc ttggcagcca taaataataa tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcttct tggattaaca gtgccacttt agcagttgaa accctctgaa tttcttgtag
     6481 atacctccat tggtcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atggtaagct tctccttgaa aaggcaaggc aatcaaattt ccaaatcccc cccttaggaa
     6601 ggacatcctg atttggaaac atgcgatcaa aagaatcaaa ggacagttgc atactttcct
     6661 gcattgccag ttctatcagt ttctttccaa acaagcgagc ctctcgactc ggaatcgctt
     6721 cctcaaagaa gaaccaaata tggagtccgt gacccgaacg agaaatctct aaatgggctt
     6781 ccatctggcg ttccctggct attcttcgaa tggttaaacc agcttctttc caatctcctt
     6841 catcaaaatc cagtaccaaa aaatgacagc tatcatctaa gtgcatagga aagataccga
     6901 tagctgtctc cccacaaaaa tgagatttca aaacggagtc cgtcaatgtc tggaaactcc
     6961 gtttttcaag tggcaactgc ttccaaccat aatcatagga aggaaaatac tgaattttcc
     7021 cttgatcatt gataaaactc ttagcataaa catcataacg gccagcaaac acggaggtaa
     7081 acaattgtaa tttttcttgc gtcgtcaagt gactactttg aagttggaac atctcctcga
     7141 accgagagcg ttccatcaca aactgactct tgtctttaag acgtttacac aagaaaaact
     7201 cactatcccc attaaaagaa gaaaagacat caagtacttc taccacaatt ccatccaaag
     7261 acacaaaaat agccataaca atcacctcct tgattcctat aggctgatta taacaagaat
     7321 ggctgaaatt gtacacgaaa ataaaatccg aatagcactc attttgtatg cgactaatag
     7381 tccatctcgc tccggaatgt acgaagtaaa tagagtttaa acgagcagtc tataaaattc
     7441 aaaaaacgca tcatatc
//
LOCUS       DAVBNN010000075         7400 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBNN010000075 DAVBNN010000000
VERSION     DAVBNN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.075"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ847_001870"
     CDS             226..6657
                     /locus_tag="VQ847_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3051164.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ847_001871"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ847_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2890 a          993 c         1428 g         2089 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact
//
LOCUS       DAVBNN010000076         7292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBNN010000076 DAVBNN010000000
VERSION     DAVBNN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.076"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(112..387)
                     /locus_tag="VQ847_001872"
     CDS             complement(112..387)
                     /locus_tag="VQ847_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3051165.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VQ847_001873"
     CDS             complement(494..1333)
                     /locus_tag="VQ847_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3051166.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VQ847_001874"
     CDS             1475..2323
                     /locus_tag="VQ847_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3051167.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VQ847_001875"
     CDS             complement(2416..3333)
                     /locus_tag="VQ847_001875"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3051168.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VQ847_001876"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VQ847_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ847_001877"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ847_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3051169.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VQ847_001878"
     CDS             complement(4596..4940)
                     /locus_tag="VQ847_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3051170.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ847_001879"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ847_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3051171.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5488..6087)
                     /locus_tag="VQ847_001880"
     CDS             complement(5488..6087)
                     /locus_tag="VQ847_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3051172.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6856
                     /locus_tag="VQ847_001881"
     CDS             6557..6856
                     /locus_tag="VQ847_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3051173.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7075..>7292
                     /locus_tag="VQ847_001882"
     CDS             7075..>7292
                     /locus_tag="VQ847_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3051174.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         2335 a         1474 c         1193 g         2290 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgac
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggtat taccctcatc acattttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaaaat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggtgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattat acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatccgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg atatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcacccctca gctcgccatc ttcggctctc
     4921 tcaaagactg cttgtatcat gtgttctcct taaaattaag cgttaattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa caactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa tgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacaa
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatca
     5461 agctttttct tttacttttt tctgccacta ggcaaaaagc atactgagat aaaaaatgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaaa caggctaaca aatatgaacc cttcacgcaa
     5641 aaaaggagtg tgcttagttc ggaaataatc tccaaaagct agcattgttc gtttgatatt
     5701 ccctgtcata aaggcattat tgtaggcaat acccgaaacc tcaccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggctgcac tagatagata ttatctacag tttgtggcac
     5821 aaaaccaata attattgata ggattgctaa aggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccattataa acgttattaa
     5941 ggttaaaagc ttatccctaa catccgaaac attattttgt attagctcta ccgaaagaaa
     6001 gacaacattt ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa atgtcaaaaa agtgctaacc ttttagactg acgtgatatt
     6121 tttcttatag gtaataacct cattttccct cccattgtat tttctcttag aaatattgta
     6181 ccatttcttt ctaaaaaatc gtagactacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acctgggctt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcga ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aggaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaacaaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatactt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc cactatagat attatggagc ctattttatt gtagaaaaaa
     7021 atcccataag atctataatg aaaagcgacc aaacaactca ttagaaagat tcatatggga
     7081 caattacatt ttatcacaaa attactagac attaaagacc ctaatatcca gattttagac
     7141 atcatcaata aggatacaca caaggaaatc atcgccaaac tggactacga cgccccatct
     7201 tgccctgagt gcggaagtca aatgaagaaa tatgactttc aaaaaccgtc taagattcct
     7261 taccttgaga caactggtat gcctactaga at
//
LOCUS       DAVBNN010000077         7224 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBNN010000077 DAVBNN010000000
VERSION     DAVBNN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7224
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.077"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(83..523)
                     /locus_tag="VQ847_001883"
     CDS             complement(83..523)
                     /locus_tag="VQ847_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3051175.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETRQAKPDEIRLPAKQNMV"
     gene            complement(525..1562)
                     /locus_tag="VQ847_001884"
     CDS             complement(525..1562)
                     /locus_tag="VQ847_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3051176.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1660..2985)
                     /gene="brnQ"
                     /locus_tag="VQ847_001885"
     CDS             complement(1660..2985)
                     /gene="brnQ"
                     /locus_tag="VQ847_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3051177.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3156..3248)
                     /locus_tag="VQ847_001886"
     CDS             complement(3156..3248)
                     /locus_tag="VQ847_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3051178.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3291..3443)
                     /locus_tag="VQ847_001887"
     CDS             complement(3291..3443)
                     /locus_tag="VQ847_001887"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3051179.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(3603..4181)
                     /locus_tag="VQ847_001888"
     CDS             complement(3603..4181)
                     /locus_tag="VQ847_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3051180.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4235..5635)
                     /gene="pepV"
                     /locus_tag="VQ847_001889"
     CDS             complement(4235..5635)
                     /gene="pepV"
                     /locus_tag="VQ847_001889"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3051181.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5648..6253)
                     /locus_tag="VQ847_001890"
     CDS             complement(5648..6253)
                     /locus_tag="VQ847_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3051182.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6424..7224
                     /locus_tag="VQ847_001891"
     CDS             6424..7224
                     /locus_tag="VQ847_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3051183.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
BASE COUNT         2118 a         1623 c         1444 g         2039 t
ORIGIN      
        1 aaaagtggta cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatacca tattttgttt cgcaggaagt ctgatctcat
      121 ccggttttgc ttgacgggtt tctgcggtca tttcttcaaa agggacccac cagactggcc
      181 cacgtccatt gagaccgtga ccattcatgt cacctgttcg tctaggaaac agatgccaat
      241 gaagatgggc atcgccattt cctagcagtt cgatattcat tttctcagca gcaaaggcct
      301 tggcaactgc ctcttggacc acactcattt cttctagaaa acggagtctt gtctcctttt
      361 tcaaatggtg caattccgtg acatgttcct tggctagaaa gagactatag cctgcaaaat
      421 actgatggtc tccaatcaca agatagcctg tttccaactc tttgacaaag tagggatttt
      481 ctcccttctt gatgagctca attctctggc aaataaggca catatcaatc tactaaattg
      541 cttctaagat aggcatcgac cattcgttct gttgcgacca ccgagtcaat atgagtgcgc
      601 tcataagaat gactagactc gatacccgca ccaagaaggg catgcttgac ctctgcccct
      661 gcagacatag ccgctgaagc atccgaacca taaaatggat agatgtccag cttaaaagga
      721 atatcttgct ctttagccaa ggcaaccaag tgttgacgga agtcatagtg ataaggacct
      781 gaagcatcct tgacacagat agatactgtg tactcatctg tctgctggtc atctcccata
      841 gctcccatat ccacagccag atattctact acctgagcag gaatgttaga attagcacca
      901 tgtcctactt cttcaaaaac tgaaaaagca aaatgagttg ttactggcaa ttcaatcttc
      961 tctttcttat aaatacgaag caggttgagc aaaatcgctg cgctgacctt atcatccaaa
     1021 tgacgagact tgataaaacc tgtatcagtc acaacagttc gtggatcgaa gctgataaaa
     1081 tcaccgacct caatcccaag agcacgagtt tctttttcat tgcttacttt tacatccaaa
     1141 cgcacttcca tattgtcctg cgtgcgttct gcagttcctg catccttgta gacatggcaa
     1201 gaagtttggt ggatgaggat ggttcctgat accttttgac ctgtgctagc cacatgaacg
     1261 gtacagtttt caccttcaat catgttccaa ggaaaaccac cgatacggtc caatttaaga
     1321 cgaccatctg gtttgacagc acgaacaata gcacccagcg tgtccacatg ggcagtcaca
     1381 tagcgatgtt gctcatcatt ttgacctttg atggtcacat tgacaccacc cttggctgtg
     1441 cgaactggct ggtaaccaaa accttctaga gtcttgacta aataattcga aatttcacga
     1501 gttaagcccg ttggcgatgc gatggctgtc agttctttga tatattctac tgtttgattc
     1561 atttcttcac ctctttcgct acctattata acacatttat catcggataa aaaaagaaaa
     1621 tcactcctgt agacttggct acaaaagtga tttaagtgat tattccattt caaaaacatc
     1681 gctttcttgc ttgtttggta gaaccaatga gagcaagatt ccaacaatgg ctggcaccaa
     1741 ccatgggaga gatgccttgg caaaaggaag aacgctaaca agatttgcaa gaaactcaac
     1801 cttaaacgag cttcctagta cgcttgcaat ggcaataact gtaaccacag caattgtcaa
     1861 ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca atgacaatca taacgatagc
     1921 aatcgtgatt gggtacaaga taaccagtac tggaattgag tacttgataa tcgcatcaag
     1981 acccaaattg gcaatagcaa atccaatcaa ggtaaaggct gtcgcataaa ccttgtagct
     2041 gatttgtggg aagcgctcat taaagaactc agctgttgac acaatcaaac caacagtcgt
     2101 tgtgaagcag gttacggtaa ccatagctgc aaggaagagt tgagctgttg agccaaagat
     2161 ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt ccacccttca tcgcttcagc
     2221 tggtactggg aaatgatttc caagaaaacc taaaccaatg taaagagcgc tgaaggcaag
     2281 ggcaacaacg ataccaataa cccaaatagt tgaaatgtat tctttcttac ttgaaaatcc
     2341 aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc actgaggcaa gggcgtccaa
     2401 ggtattgtaa ccttctagga aacctgtacc aaaggcagaa gcttgataag cagctgaagc
     2461 agcttgagga cttgttccac catatttgat agctcccaga acgaccaaga taacaatcaa
     2521 aattgcaaag actggcgtta aaatacgtcc aatgcggtct aagatttttg atggattaag
     2581 cgaaatcaaa taggctgccg caaaatacag aaccgtaaat acaatcaagc caagtccttt
     2641 atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa gctgttgtag cagtacgtgg
     2701 ggtagcaaag aatggaccga ttgacaagta aagaactgag aggtaaagag tcgcaaacca
     2761 aggcgctatc ttcgttgaaa tctcgtagat atatccttta ggatttagcg ttccaataat
     2821 aagggtcaag acggcgatac caacgcctga aaagacaaaa cctgcgatgg caggaagaaa
     2881 atgttctcca gatagagcac ctagagaagg cggaaaaatc aagttccccg caccaaaaaa
     2941 tattccaaac aggagcaaac ctgttagggt acctttttta gccataaaaa tctccttcat
     3001 atttataaaa tactgaccta gtataccacg attaggagtc tgaaaaaagc atcacgaggc
     3061 aaatattaaa tgttttcaat tttcttaaaa ataagaatta tctaaaaata aaactctcct
     3121 acccagtcca caccaagtag gagaaatgca aaattttaaa gttcttcaaa ggctaacatg
     3181 ccaccctgga cattgataac attataacct tgttctaaca ggaattggca agcacgcgcc
     3241 gatctcattc cagatttgca aataatataa tgcaagcgat ctttgtccaa ttaatcataa
     3301 ctatcagcca attgactaag cggtaggttg tgggcacatt ctaaatgaag agctgcaaac
     3361 tcatccactt ctctcacatc cactagagaa agctggtcgt tttggtaaag ctggtaaaat
     3421 gcgtcaaagg ctatttcttt cattcttttt cttctaatac tcttcgaaaa tctcttcaaa
     3481 ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt cgtcagtttt atctgcaacc
     3541 tcaaagctgt actttgagca gcctacgact agcttcctag tttgctcttt gattttcatt
     3601 gactataaaa tggttttaat tctttttttc aaatctggca ctacttctgc ctcaaaccaa
     3661 ggatttttgg ccatccagat ttgatttcgt ggtgatgggt gaactagcgg aaaataggct
     3721 ggcagatagt ctttatagtg tttcaccctc tccgttacct tcccactgat tttctcctgt
     3781 aaatagtagg cttgggcata ttgcccaatc aagagggtta actgaatatc aggcaattcc
     3841 tgtaagagct gcggatgcca tttttctgca aaacctgtac gaggcggaag atcacccgac
     3901 ttgccatgtc ctggaaagta gaaatccata ggcaaaacag caaaataacc tgaattgtaa
     3961 aaggtatctt catccacacc tagccagtcc cgcaagcggt caccactttt atctttccag
     4021 taaaggcctg cttcttgagt tttaagtccc ggagcctgac cgatgatatt gatgcgagca
     4081 gtttttggcg ctgcaaagag aggctcaatg ccacgctctg tatagctggc attctgtgaa
     4141 tccgccatga tagcctgttt gattctttcg atttgagaca tctactttcc ctccaaaaag
     4201 aagtccaagc ataagatctc agacttctat cgttttattt gatcaattcg taaatagctt
     4261 cggcataaat tgctgctgct cggaaaagat catccaaggc gataaattca ttggcttggt
     4321 gcatggtatc aatcgagtct gggaacatag caccgtaggc aactccgcgt tctagcaagc
     4381 gaccaaaggt tccaccaccg atgacttgtt catgaccttt aaggccagtt tgtttttcat
     4441 agatattcaa caaggtttgc acaagtggat cttccattgg cacatagtga ggcgtgtgac
     4501 cgtgttcaga caggctaaca gaaacaactg gcaagttttc aaggattgac ttgatttgtt
     4561 ctggacttgt tccttttgga tagcggatgt tgagggcaat ggtattatca gcacttgttt
     4621 catcgaagcg gaagacgccg gcattcatag aaagagcacc catcttttca tccacatgag
     4681 caatcttaag attttcaccc tcatgatcgt tcaagagaat tttacctgcg atgtcaaggt
     4741 agtctttggc tggaccagca aagccaaact ggctgaggaa gagggcaagg taagttgcgc
     4801 cattgacacc tgaagcaggc atagcaccgt gggctgattt accaatgatc gtcaccttgt
     4861 atttgccagc ttcttcttgg agttctcctc taagtttgtg ttctgcaaca aaggcatcta
     4921 gtttagcttg caagtcagcc aaatcacctg aaacgactgc tgttgctgat tctggtacca
     4981 tattttcacg taaaccacct gtaaagctgt gaagacgggc agcacctgta ttttctcctg
     5041 caaagtggag gtattccgtg atatttcctt tttcaccatt gatgattgga aattcagcat
     5101 ctggagagaa accgaaatct ggtttggcaa gtcctacgtg ctcaaagtag tagtccatgt
     5161 ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg aactttctta gaagttggaa
     5221 gacccaattc tttgatgatt ttcaaaccat agtaacaagc tgttgtagga cccttatcgt
     5281 ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt tggtgtgtaa ggatctgtgt
     5341 cccaaccgct accagcaggc accacatcca tatgggcaaa gattccgaga acttcttctc
     5401 catcaccaaa ctcaaaatgt cctgcgtagt tatcgacatt cttagttggg tagccatcgc
     5461 ggtctgcgat ttcaaggaat ttctccaagg cttttactgg accaggtcca aatggatgct
     5521 gggcatcagc cttgctatca tcacgttctg agttgatttc caaaaggcta aacaagtcag
     5581 ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa atcaattgct gtcatttttt
     5641 cttctttcta tcttttctcg atgatttcat ctactggcaa gcggtagctt ggttccaatt
     5701 tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg gaaacggtct tcgatttcca
     5761 aaacttcatt aacttttgat ttgtcaaaac caaggataat attggaacca attccttggt
     5821 ctgtaagagc gagaaccaag ttcatagcaa ccaaacctgc attgagtgct aggtagtcgc
     5881 tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa atttttcatg aagtattgaa
     5941 gttgctcttc agaaaagtta ttagcaccac caacacgggc aatcttacga gcacgtttgg
     6001 ctaagtccgt atctgtaaac aaggcaatgg ttacaggcgc tgatgatacc tgttcaaaat
     6061 tggaaccata agctaacttt gccagttcag catttttctc acgtaccacc acaaatttcc
     6121 aaggctggct gttgtgggcg cttggcgcca aggttgcaat ttcgatagcc gtacgcacat
     6181 cttttggatc aacaggctta tcagtaaaat gcttagtcgc atgacgtttt ttatttaatt
     6241 caagaaattt cataatcgat ttccttttct aattctactg cttccattct accataattt
     6301 gaaagagctt gcagggattt ttcatgatta agtttttcta tcacagacat aaaagatata
     6361 tattggttta tcaggaacat ttctgataaa ctagcaagta ctttacattt gaatggagac
     6421 agtatgaaaa aatttagcct attactagct atcctaccat ttttggttgc ctgtgggaat
     6481 caagctacac ccaaagagac tagcgctcaa aagacaatcg tccttgctac agctggcgac
     6541 gtgccaccgt ttgactacga agacaagggc aatctgacag gcttcgatat cgaagtttta
     6601 aaggcagtag atgaaaaact cagcgactac gagattcaat tccaaagaac cgcctgggag
     6661 agcatcttcc caggacttga ttctggtcac tatcaggctg cggccaataa cttgagttac
     6721 acaaaagagc gtgctgaaaa atacctttac tcgcttccaa tttccaacaa tcccctcgtc
     6781 cttgtcagca acaagaaaaa tcctttgact tctcttgacc agatcgctgg taaaacaaca
     6841 caagaggata ccggaacttc taacgctcaa ttcatcaata actggaatca gaaacacact
     6901 gataatcccg ctacaattaa tttttctggt gaggatattg gtaaacgaat cctagacctt
     6961 gctaacggag agtttgattt cctagttttt gacaaggtat ccgttcaaaa gattatcaag
     7021 gaccgtggtt tagacctctc agtcgttgat ttaccttctg cagatagccc cagcaattat
     7081 atcattttct caagcgacca aaaagagttt aaagagcaat ttgataaagc gctcaaagaa
     7141 ctctatcaag acggaaccct tgaaaaactc agcaatacct atctaggtgg ttcttacctc
     7201 ccagatcaat ctcagttaca ataa
//
LOCUS       DAVBNN010000078         6938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBNN010000078 DAVBNN010000000
VERSION     DAVBNN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.078"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(57..287)
                     /locus_tag="VQ847_001892"
     CDS             complement(57..287)
                     /locus_tag="VQ847_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051184.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(305..946)
                     /locus_tag="VQ847_001893"
     CDS             complement(305..946)
                     /locus_tag="VQ847_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3051185.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(958..1692)
                     /locus_tag="VQ847_001894"
     CDS             complement(958..1692)
                     /locus_tag="VQ847_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3051186.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1695..1892)
                     /locus_tag="VQ847_001895"
     CDS             complement(1695..1892)
                     /locus_tag="VQ847_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051187.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1892..2098)
                     /locus_tag="VQ847_001896"
     CDS             complement(1892..2098)
                     /locus_tag="VQ847_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3051188.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2108..2422)
                     /locus_tag="VQ847_001897"
     CDS             complement(2108..2422)
                     /locus_tag="VQ847_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051189.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2647..2727)
                     /locus_tag="VQ847_001898"
                     /pseudo
     CDS             complement(2647..2727)
                     /locus_tag="VQ847_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2718..4007)
                     /locus_tag="VQ847_001899"
     CDS             complement(2718..4007)
                     /locus_tag="VQ847_001899"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3051190.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4104..5333)
                     /locus_tag="VQ847_001900"
     CDS             complement(4104..5333)
                     /locus_tag="VQ847_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3051191.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ847_001901"
     CDS             complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ847_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3051192.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6501..6842
                     /locus_tag="VQ847_001902"
     CDS             6501..6842
                     /locus_tag="VQ847_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3051193.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2248 a         1441 c         1275 g         1974 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat
       61 tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca
      121 atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact
      181 gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa
      241 aatagaacga ctgcctgaat cactgctact aaaattactc gtttcatgtg acctcctgac
      301 tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa
      361 tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa
      421 aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag
      481 ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg
      541 ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga
      601 atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat
      661 catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca ggaagccaaa
      721 taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac catttgtaaa
      781 tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca tagggtgaag
      841 cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata aataaaaagg
      901 atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat aactccttta
      961 tttgaaataa cgttttacca taggtaactg catcacattg atataaacat ggatggctcc
     1021 tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa
     1081 aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc
     1141 caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg
     1201 tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt
     1261 ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt
     1321 atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt
     1381 aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc
     1441 attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa
     1501 gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca
     1561 tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat
     1621 ccctacaaac atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg
     1681 tttctttttc atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc
     1741 cattcagtta ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga
     1801 ttaaaccagc ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc
     1861 actacataat aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg
     1921 attcgactgt ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt
     1981 actcatcccg ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt
     2041 cggtttgatt gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcacgt
     2101 tacacaccta ctctccgtca aattcaacgg tttggatatc ttcaatacgt tgcaacttga
     2161 atttttcttt tcccgtatta tcaacactac gtagtttgac ccattcctca tcaacatcca
     2221 caacttccca gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca
     2281 tttcttgtaa taatctcgac atttctgcgt ttcctttctc ttttcgctca agttttttga
     2341 ttttattctc tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata
     2401 gtataaatcc tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt
     2461 cattgtaaca tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg
     2521 tcattttgca aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata
     2581 ctcttctaaa atctcttcaa accacgtcag cttcaccttg ccgtaggcat ggttactgac
     2641 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg ctagcttcct
     2701 agtttgctct ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag
     2761 ttttggctga ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgact
     2821 gtcacttgtc tgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag
     2881 acatcggctg acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg
     2941 aaaccttgtt ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc
     3001 aagactgcga tatagacatc tagggcattt tcgataggga gggccacgcc ttgtttttca
     3061 aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct
     3121 ccaaagtaag caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc
     3181 tcaatctctg tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata
     3241 ttggtatcga tgatgtaatc tactccaaga ttttccaaca tctgactcac agcatcaaaa
     3301 tgagtttggc tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc
     3361 ttgtcttctt tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg
     3421 ctatccttag acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag
     3481 gctgcacggc tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg
     3541 atttccttca aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta
     3601 gaaccaaaac actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc
     3661 tcataacgga acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggagcg
     3721 aagagtttat tttccacata ggcacggaca acgggcgcag ttccttctgg acggagggta
     3781 atatggcggt cacccttgtc atagaaatcg tacatttcct tggttacaat atctgttgta
     3841 tctccgacag agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg
     3901 tagttgtagc gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac
     3961 tcagcaggta aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt
     4021 taaacttaat agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta
     4081 ggatttagat atcatttttg agattaagaa ttgtcaaaaa aaatagctag caaggaaaga
     4141 ccaacaaata gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct
     4201 gttcccacag gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga
     4261 acctctggag ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac
     4321 acatacagag taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc
     4381 aaaccaacta gactaagccc tacggtcgcc cacatcatca atctaggcaa ggactgcttc
     4441 ccaaaataat cattgcccgt aaggctactg atgatgactg ctactaaaac acagaattga
     4501 ttgataaata gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata
     4561 ttataaattc cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata
     4621 aaaccaaagt ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt
     4681 aggaactggt ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac
     4741 attgacaggc tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag
     4801 caggcattga ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact
     4861 ccgaaagctt gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc
     4921 tccatcagat catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca
     4981 aaatcactga tgatatcact aatgacattg atcaaacaca ggatagaaaa ggcaaagaga
     5041 ctagcttgct gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta
     5101 tagaccatcc atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta
     5161 aagagggtcg gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac
     5221 aaggtcgatg catagacgat aaagaccagg ttgaaaatcg aagcaccaaa agcattgaag
     5281 aagcgtgata aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat
     5341 ctcccttctt gttcgaacct ctatatgaag tatgactata gtatagcact tagaaatttg
     5401 agagggagaa ctcttgaata tatgcaacaa ataaaatgag caaaaagaaa cgatagaact
     5461 tttgtaatga cctgagagag ggcaatagtt ctatcgcttc aaattttttc ttggtttgca
     5521 gatattcaac attcggtcgt atttctatag tattcggcag atttattaca gccaagcatc
     5581 tcaaaaatac ggacagcatc ctccatcttt ttctggcctt ccttgactct accttgcttg
     5641 ctatcaagga gaccttctgc ccacagataa acaattcgga aataggtctc attttccttg
     5701 tagaaatgct cttcgataac acgtttaaaa taataggcat tggtaaattc ttcacactca
     5761 atactagcta aaaagccgtt caatagtata gtatgaaaaa ggtttcgatt gccagacatt
     5821 tccattagaa aatcagattt acgtaccatt tctcgtacat atctagtaaa aagagaaaca
     5881 gataaaaatg gagaactgac tgaaaataaa ttgagttcat agattcccca gatctcggta
     5941 gaaaacaaat aatcatgaag gacttttcct tcctctgctg ttaagtctac cctttcatct
     6001 atgctcttca tataagactt gataataatg gcatttagaa tatgtttctg tttgttgtga
     6061 gaatgggcat gcttttgata ctccctgcga tataagtcct caagaggtgc tatattcttt
     6121 ggttccaaga catctgtaat ttcttttctc aactcagaat ctgtatcata ctggaaacct
     6181 ctcgccagaa agaggatctc ctccacactg gcagatatat tttccagagc aaatagaaac
     6241 ttttccaccg aaagctcact ctgacctgtt tcaaaacggg acaacataga cggcgaaaat
     6301 tgtcctccgg ttgcttgtct cagtgagata tttcttgact ctcgtaattg tctaaagact
     6361 tttccaatct gctccataga cttccccttg attccgtatt ttcttcattt tatcatattt
     6421 ttcagaaaat taatcaaaag cttgccaaat tgtcagaatt atgagaaaat agaggatatt
     6481 tatcacatgg agggactgct atgagagacg atatcaaaat caatgaccgt gctttggcct
     6541 tgcaagacca aattatcgaa aaactagaga aagtttttga tacagatgtg gaattggatg
     6601 tttacaatct aggtctgatt tatgaaatca atctggatga aacggggctc tgcaagattg
     6661 tcatgacctt caccgatact gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg
     6721 caggtctgaa acaaatcgag ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg
     6781 cttggaaaat cacacgaatc agtcgctatg gccgtattgc ccttggacta ccacctcgtt
     6841 aagcaggcca atcactttta aagatgaaaa aagcaagccg aaaatggctt gctttttgat
     6901 actcaatgaa aatcaaaggg caaactagaa aactagcc
//
LOCUS       DAVBNN010000079         6806 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBNN010000079 DAVBNN010000000
VERSION     DAVBNN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.079"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ847_001903"
     CDS             complement(<1..207)
                     /locus_tag="VQ847_001903"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051194.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ847_001904"
     CDS             complement(275..916)
                     /locus_tag="VQ847_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3051195.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ847_001905"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ847_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ847_001906"
     CDS             complement(3216..4115)
                     /locus_tag="VQ847_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3051196.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ847_001907"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ847_001907"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3051197.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ847_001908"
     CDS             complement(4747..5520)
                     /locus_tag="VQ847_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3051198.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ847_001909"
     CDS             complement(5825..6718)
                     /locus_tag="VQ847_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3051199.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
BASE COUNT         1906 a         1622 c         1175 g         2103 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagcagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaat
//
LOCUS       DAVBNN010000080         6787 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBNN010000080 DAVBNN010000000
VERSION     DAVBNN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6787
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.080"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..379
                     /locus_tag="VQ847_001910"
     CDS             <1..379
                     /locus_tag="VQ847_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630-like element IS630-Spn1 family
                     transposase"
                     /protein_id="HET3051200.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQN
                     FLLPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEAFLSCSCFN"
     gene            440..1402
                     /locus_tag="VQ847_001911"
     CDS             440..1402
                     /locus_tag="VQ847_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3051201.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1579..2586
                     /gene="gap"
                     /locus_tag="VQ847_001912"
     CDS             1579..2586
                     /gene="gap"
                     /locus_tag="VQ847_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3051202.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2653..3489)
                     /locus_tag="VQ847_001913"
     CDS             complement(2653..3489)
                     /locus_tag="VQ847_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3051203.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3615..5810
                     /locus_tag="VQ847_001914"
     CDS             3615..5810
                     /locus_tag="VQ847_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3051204.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5863..6015
                     /gene="rpmG"
                     /locus_tag="VQ847_001915"
     CDS             5863..6015
                     /gene="rpmG"
                     /locus_tag="VQ847_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3051205.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6025..6201
                     /gene="secE"
                     /locus_tag="VQ847_001916"
     CDS             6025..6201
                     /gene="secE"
                     /locus_tag="VQ847_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3051206.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6256..>6787
                     /gene="nusG"
                     /locus_tag="VQ847_001917"
     CDS             6256..>6787
                     /gene="nusG"
                     /locus_tag="VQ847_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3051207.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2111 a         1190 c         1465 g         2021 t
ORIGIN      
        1 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
       61 tggtgaatta atcgctccaa tgacttacga agagacgatg acgagcgact tttttgaagc
      121 ttggtttcag aattttctct taccaacatt aaccacacca tcggttatta ttatggataa
      181 tgtaagattc catagaatgg ggaagctaga acttttatgc gaagagtttg ggcataaact
      241 gttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      301 caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc ttttacgagg cttttttatc
      361 ctgctcttgt ttcaattgac tatatatcac ggatacagtt gggaaagaag ctattaaata
      421 tttggagagt ccttttggga tgaacatgtc aaatattact atagatgggc aagaaataga
      481 tctgagtcaa acgatgcctt cttatgctca agtagtgagt ctttatgatg atacaagtat
      541 ctctgttagt agtaatgaga cggacaaagt gttggctgga tccctctata ctgatacaaa
      601 tgaacaggga ttaacgattc caagcagttt actaaaaaat tggaatgaac agacaggaaa
      661 aaatttgaca gctaatgatc ttattggcaa atcagtctca gccagcattg tagaaagtgc
      721 tgccgaaact agtaagattg ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga
      781 agatgacatg gaggacagca acagtttcat gctgtctcat caaatggaaa cgattttgaa
      841 agaggctgga tttacgaaag ctgtatctta ttttatcttg gaactcaaag atccatcaca
      901 gacaaaagta gtaacagaag aattacagaa aaataagaag tatactgtgc tttctcaaca
      961 gagagttctt gatattgtga ttacctttat tcgtgttatt cagggattat tgattgtgct
     1021 ttcatcacaa gctattgtgg tagcagcggt tatgattggt atcattattt acatcaatat
     1081 catgcaacgt tctaaggaaa taggtgtcat gaaggcagtt ggttatcaga atcgtgatgt
     1141 caaaggaatt tttatttacg aggctatctg gattgtaggc atcgccttgc tgctggcatt
     1201 tttggttgca caaggggtgg gaagtttggc gaatgcgatt gtaagtcact tttacccatc
     1261 catcactaag gtttttgaat taaatctttt atctgtttta ggaactctag ttttcgctct
     1321 attacttggt tatgtctcag cctacttccc ggcgcgtaag attagtaaaa tggatcctgt
     1381 agaaccgtta cgctatgaat agtaagggat tccttgattt acagtcttaa aaagaaacta
     1441 acatagaaaa acaatggcca tacttgcaat tcaactcaaa tagttgtata ataggtttgt
     1501 tgaaaggtga tttgtagtga ttcaagttac tcttttcaca ataaaaattt catgattttc
     1561 ataaggagga aatcactaat ggtagttaaa gttggtatta acggtttcgg acgtatcggt
     1621 cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg catcaacgac
     1681 cttacagatc cagttatgct tgcacacttg ttgaaatacg acacaactca aggtcgtttc
     1741 gacggtactg ttgaagttaa agaaggtgga tttgaagtta acggtaaatt cgttaaagtt
     1801 tctgctgaac gtgatccaga gcaaatcgac tgggctactg acggtgtaga aatcgttctt
     1861 gaagctactg gtttctttgc taagaaagaa gcagctgaaa aacaccttaa aggtggagct
     1921 aaaaaagttg ttatcactgc tcctggtgga aacgacgtta aaacagttgt attcaacact
     1981 aaccacgacg ttcttgacgg tactgaaaca gttatctcag gtgcttcatg tactacaaac
     2041 tgcttggctc caatggctaa agctcttcaa gataactttg gtgttgttga aggattgatg
     2101 actactatcc acgcttacac tggtgaccaa atgatccttg acggaccaca ccgtggtggt
     2161 gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac tggtgctgct
     2221 aaagctatcg gtcttgtaat cccagaattg aacggtaaac ttgacggatc tgcacaacgc
     2281 gttccaactc caactggatc agttactgaa ttggtagcag ttcttgaaaa gaacgttact
     2341 gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg ttacacagaa
     2401 gatccaatcg tatcttcaga tatcgtaggt atgtcttacg gttcattgtt tgacgcaact
     2461 caaactaaag ttcttgacgt tgacggtaaa caattggtta aagttgtatc atggtacgac
     2521 aacgaaatgt catacactgc acaacttgtt cgtactcttg aatacttcgc aaaaattgct
     2581 aaataattct tgagttgata gaaagcaagg ctttgtggtc ttgcttttta tatagaaaaa
     2641 tggatgacac gatcatccat tcttttttaa ttctttttca aatgtatttg aaagggtagt
     2701 gaaagttagc ctctctaaag taagtgggtg ggtaaaggaa agtcggaagg catgaagcat
     2761 aagccggctt gtctttgatt tactattata gagagggtct cccaggatag gaagattatg
     2821 atgcaaaagg tgcacacgaa tctgatgggt tcgccctgtc tttagcttgc aatgagccaa
     2881 ggaagtcttg tttgagaatt gctttaatct gcttacatgc gtttcagcat attgcccatt
     2941 ttttgcatca actattcttt ttctacgatc atggcgatca cgtccaattt tgtctctgaa
     3001 aacaagttct tttctgttga tatttccatc aactagagcc caatattctc tagaaatctc
     3061 ttttttctcc aataagcgat tgagaatggg caggataaaa ggatttttgg caaagagaac
     3121 taagccactg gtttccatgt ccagacgatg aacgacatag caggtttggc caacataggt
     3181 actgacatgg ttaagaaggg caatttcgtt tggttgatta ccatgcgttt tcatcccctc
     3241 tggtttgttt acaataatca agtgttgatc ttgataaact tcctgcacta agtctgggtt
     3301 gccccaaggg atcgtctttt ggggataatc ttcctcgtca aaagtcaact ggcaaacatc
     3361 tccaggattt acgatttcgt tccagtggac ttcttcttga tttatcaaaa tatgtttctt
     3421 gattctcaaa aaatgacgga tttttctagg gatgaggagt tgttcctcaa gtaattgctt
     3481 taccgtcatt tgaggtatag aggcgggtaa tgtaaatgtg aattgcatac agatattgta
     3541 acaaaaaaag ccctatttgg ataggaaata gctaaattct tgtcttccta tgatgaagat
     3601 gataaaataa acgcatgaaa ttagataaat tatttgagaa atttctttct ctttttaaaa
     3661 aagaaacaag tgaactagag gactctgatt ctactatctt acgtcgctct cgtagtgatc
     3721 gaaaaaaatt agcccaagta ggtccgattc gaaaattctg gcgtcgttat catctaacaa
     3781 agattatcct tatactaggt ttgagtgcag gcttgctagt tggaatctat ttgtttgctg
     3841 tagccaagtc gaccaatgtc aatgatttgc aaaatgcctt gaaaactcgg actcttattt
     3901 ttgaccgtga agaaaaagag gctggtgcct tgtctggtca aaagggaacc tatgttgatc
     3961 tgactgatat cagtaaaaac ttgcagaatg ctgttattgc gacagaagac cgttctttct
     4021 ataaaaatga cgggattaac tatggccgtt tcttcttggc tattgtcact gctggacgtt
     4081 caggtggtgg ctctaccatt acccaacagc tggctaaaaa cgcctattta tcacaggatc
     4141 aaactgttga gagaaaagcg aaagaatttt tccttgcctt agaattaagc aaaaaatata
     4201 gtaaggagca aattctaacc atgtacctta acaacgctta ttttggaaat ggtgtgtggg
     4261 gtgtagaaga tgcgagtaag aaatactttg gagtttctgc atcagaagtg agtctggatc
     4321 aagctgcgac tctggcaggg atgctcaagg ggccggaact gtataatccc ttgaattccg
     4381 tagaagattc tactaatcgg cgcgatactg tcttgcagaa tatggttgca gcaggatata
     4441 ttgataaaaa ccaagaaacc gaagctgctg aagttgatat gacttcgcaa ttgcacgata
     4501 agtatgaagg aaaaatctca gattaccgtt acccctctta ttttgatgcg gtggttaatg
     4561 aagctgtttc caagtataat ctaacagagg aagagattgt caataatggc taccgcattt
     4621 acacagagct ggaccaaaac taccaagcaa atatgcagat tgtttatgaa aacacatcgc
     4681 tatttccgag ggcagaggat ggaacgtttg ctcaatcagg aagtgtagct ctcgaaccga
     4741 aaacaggggg agttcgtgga gttgtcggtc aagttgctga caatgataaa actggattcc
     4801 ggaatttcaa ctatgcaacc caatcaaagc gtagtcctgg ttctacaatt aagcctttag
     4861 ttgtttatac gccagcagtt gaagcaggct gggctttgaa taagcagttg gataaccata
     4921 ccatgcagta tgacagctat aaggttgata actatgcagg gatcaaaacg agtcgagaag
     4981 ttcctatgta tcaagccttg gcagaatcgc ttaatctacc tgctgttgcc actgttaatg
     5041 atttgggtgt cgacaaggct tttgaggcag gcgaaaaatt cggactcaac atggaaaagg
     5101 tcgaccgtgt tcttggtgtc gccttgggaa gcggtgttga aaccaaccct cttcaaatgg
     5161 ctcaagcata cgctgccttt gcaaatgaag gtttaatgcc tgaagctcat tttattagta
     5221 gaattgaaaa tgctagtgga caagttattg cgaatcataa aaattcacaa aaacgggtga
     5281 ttgataagtc tgtagctgac aagatgacca gtatgatgtt ggggactttc accaacggta
     5341 ccggtattag ttcatcgcct gcagactatg tcatggcagg gaaaactgga acaactgaag
     5401 cagttttcaa tccggagtac acaagtgacc agtgggtaat tggttatact ccggatgtag
     5461 tgattagcca ctggcttggc tttccgacca ctgatgaaaa tcactatcta gctggctcta
     5521 cttcaaacgg tgcagctcat gtctttagaa acattgccaa taccatttta ccttatacgc
     5581 caggaagtac ctttacggtt gaaaatgctt ataagcaaaa tggaattgca ccagccaata
     5641 caaaaagaca agtacaaacc aatgataata gccagacaga tgataatttg tctgatattc
     5701 gagggcgtgc gcaaagtcta gtagatgagg ctagccgggc tatctcagat gcgaagatta
     5761 aggaaaaggc tcaaacaata tgggattcga tagtcaatct atttcgctaa gatgcttgtc
     5821 aaagcctagc tttcttgtta taatggataa gatggaggcg ttatggcact aaaaaaagca
     5881 agcctagctt gtgcggtttg tggttcgaga aactattcaa tcaagatcag cggaaacccc
     5941 aagcctacac gactagaagt aaataaattt tgtaagcatt gtggcaagta cactacacac
     6001 agagaaacga gataggagag agcgatgcgt tttattggag atatttttag acttcttaaa
     6061 gacacaacat ggccaactcg caaggaaagc tggagagatt ttcgttctat catggaatac
     6121 acagctttct ttgtagtaat tatttacatt tttgaccagt tgattgtttc aggtttgatt
     6181 cgatttatta acatttttta gaagattagt ggagttaatt acactagaaa tcttctattt
     6241 atgaaaggaa atatcatgga tagttttgat aaaggatggt ttgttttaca aacttattct
     6301 ggttatgaaa ataaggtgaa agaaaatcta ttacaacgtg cacaaaccta caatatgttg
     6361 gataatattc tacgcgttga aattccaaca caaacagtgc aagttgaaaa aaatggaaag
     6421 agaaaagaag tagaagaaaa tcgctttcca ggttatgttc ttgtagaaat ggtcatgaca
     6481 gatgaagctt ggtttgttgt tcgaaacaca ccaaatgtta caggatttgt cggatcacac
     6541 gggaacagat caaaaccaac tccattattg gaacaagaaa ttcgtgacat tttggtatct
     6601 atgggacaaa ctgttcaaga atttgatttc gatgttgaga ttggtcaaac tgtacgtatt
     6661 attgatggtg cttttgcaga ctacactggt aagattacag aaattgataa taacaaagtg
     6721 aaaatgatta tctctatgtt tggtaatgac acagttgcag aagtaaacct aaaccaaatc
     6781 gcagaat
//
LOCUS       DAVBNN010000081         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBNN010000081 DAVBNN010000000
VERSION     DAVBNN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.081"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ847_001918"
     CDS             138..860
                     /locus_tag="VQ847_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3051208.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ847_001919"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ847_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3051209.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ847_001920"
     CDS             complement(2467..3378)
                     /locus_tag="VQ847_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3051210.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ847_001921"
     CDS             complement(3402..4205)
                     /locus_tag="VQ847_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3051211.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ847_001922"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ847_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3051212.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ847_001923"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ847_001923"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3051213.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1388 c         1478 g         1843 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgatatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBNN010000082         6724 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBNN010000082 DAVBNN010000000
VERSION     DAVBNN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.082"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(67..927)
                     /locus_tag="VQ847_001924"
     CDS             complement(67..927)
                     /locus_tag="VQ847_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3051214.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(1049..2035)
                     /locus_tag="VQ847_001925"
     CDS             complement(1049..2035)
                     /locus_tag="VQ847_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3051215.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(2307..3782)
                     /locus_tag="VQ847_001926"
     CDS             complement(2307..3782)
                     /locus_tag="VQ847_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3051216.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(3866..4789)
                     /locus_tag="VQ847_001927"
     CDS             complement(3866..4789)
                     /locus_tag="VQ847_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3051217.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(4803..5732)
                     /locus_tag="VQ847_001928"
     CDS             complement(4803..5732)
                     /locus_tag="VQ847_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3051218.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(6051..6271)
                     /locus_tag="VQ847_001929"
                     /pseudo
     CDS             complement(6051..6271)
                     /locus_tag="VQ847_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6225..6485)
                     /locus_tag="VQ847_001930"
     CDS             complement(6225..6485)
                     /locus_tag="VQ847_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051219.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         1994 a         1356 c         1293 g         2081 t
ORIGIN      
        1 caatcctgtc tttcatggca ggatttttct atttcaaaaa agcaagtcga ttgacctgct
       61 tctgctttac tcttcttgtg ctaatgcttt aaaatctttg tctaatatgg gttgcacttc
      121 tatttgattg gcgtctagtt ggtggtaaaa agataggggt aatacctcta agaattttgc
      181 atagtccaag cgggcaatgg cttcatagtc ttctggttta gagccatctc ctgtgatttg
      241 aaccaagtca atctcccact gcacttcctt atccaccaat tgctcaatat aggctgcagg
      301 aacaaacggt tctctcggta aaactgtctt gactccttga gctagatggt aaacgccatg
      361 cacttttcct tctccatcct gatagaagga aactctcgca aagtaggcat ctgtctcttg
      421 aaccgcacgc acacgcgctt caaactgagc caagccatct gcctctaaaa agcttttcaa
      481 gttctcacga ctaaagaaaa taggattaaa aattccttgg caaatcgtaa aacgagctac
      541 agggtctgct agataggctt gaatacttgc ttggaaataa gcttcaaaat caaaaccatc
      601 tagcccttca atatcagtcc ctgtataagc aagcaaagca tctaaaaatg acttgataat
      661 ctgccagtct gtctttgtta gtaggtcagg aagatcgaca cggtaagcct tttgaccatc
      721 agcataactg accttaaaaa gaaattgtga ttgccccact atcgcacact caatatactc
      781 gagacgatta agaggctgac ggagatagac tacatcatag ctatgtgact ccaaaccgtc
      841 tagcaaggcc aagatcgact tggcattcaa aatctcttgt tctcctaaaa tgctctgttt
      901 atttggaata aaaaatgttt ttgccataac tggactcctt tgaaatcgtt tacatacagt
      961 ataccttatt tttctgaaag atacagaaac aaactttaga tttttgagta caaagcatag
     1021 aaaaacagcc cctgaggact gtttgatctt atacagtagc tgcttgatcc aagctttcac
     1081 cgatagcggc taggcgctca atcacttcag cttgtgtcaa ttcatttttt gaaacatagc
     1141 ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg aaggtacttg tcttcatttt
     1201 cttctgatgt caagatacga cggttacaga atggatttcc acagttgaca taacgttcac
     1261 atggtgttcc atcaaaccag tctttcccta cgatagttgg gttgacatgg ttgacatcaa
     1321 cggcaatacg ctcgtcaaag acgtacattt tcccatccca aagctcacct tgaacttctg
     1381 ggtctttacc gtaagttgcg attcctccgt gcaattggcc gacatctttg taaccttcac
     1441 gaaccatcca gcctgagaat ttctcacagc gaacgccacc tgtacagtaa accacgacac
     1501 gcttgtccat gaatttttcc ttgttatcac ggacccattg tggtaactca cggaagttgc
     1561 gaatatctgg gcgaatagcc ccacggaaat gtcctaggtc atactcataa tcattacgtg
     1621 tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt gaactctttt ggagacaagt
     1681 aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa gtcgttgtct tccaaaccaa
     1741 ggtggacaat ttctttcttg tagcgaacaa acatcttctt gaaggcttgt tcactttctt
     1801 cgtcaatctt gaaccagagt tcttccattc ctggaaggct gtgaacgtag tccatgtatt
     1861 tttgagttgt ttcatagtca cctgaaactg ttccgttaat tccctcgtca gcgactagga
     1921 tacggccttt aagaccgatt gatttacaga aagccaagtg gtctgcagca aattgctctg
     1981 cattttcaat tggagtataa aggtagtaaa gtaagacacg aatatctttt gccataagat
     2041 ttgttctctt ttctattctt aaattttcta aattttttat ttatctacac tagtatacct
     2101 gcttgagaaa acgaatgcaa tttatttgac tggaaattgt agagggttct cgaaatttcc
     2161 tgaatggtta aaataaggac aagagaaaac atggatatct atatccttgt gccaaaaaaa
     2221 ccactgtctc ccccagacca acctgaggaa agcagtgatt cttattttag gagttaggaa
     2281 tgaatacacg aaatcaattt agctgattat tttttgtttt tcaagaattc atcgtattgt
     2341 ttttgcattt cgttcaatac tttttcgtag gcaccttcag atttcaattt ttccatcaat
     2401 tctggaatcg ctttatctgg gtctacagta ccagtgttga tagctgtatc aaattgttgc
     2461 attgtgttag caatagctga gatttcagat ttcacattgt cagtattgaa gataaatcca
     2521 agcgctggag attctttagc ttctgccaat tctttcttag aattttcgat ttgttggtct
     2581 gtaacgtttt cgttgatgta aaggatccag ttgttaccag tgttccatcc acccatgtga
     2641 gtgtttcctt tgtagccatc aagaacgcga acacggtttt ctttaccttc aattttttcc
     2701 cagttcttgc cttctggacc gtaaacaaga ccgttcaaga gttctggatt cgtattcaag
     2761 aggttcaaga tttccattga tttttctttg ttcttagagt tgtttgagat gacaaagtta
     2821 gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa ttggtttgat ttggatatct
     2881 ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag ctggtcctac tgtttcttca
     2941 cgaacgaacc aagtatcttg ttgaaggtca aaggaagtat cgcttgttgc gacgtctttt
     3001 ggaatgtagc cagcttcata gaatttgtga agagtcttca agtgttcttt gaaacgaggt
     3061 acttcgtaac ggtttacaac tttagtagta tcgccttcaa ggtcaataac gaatggaaga
     3121 ccgtttgcta ctgggtagtc aaagttatca gatgggatga aaactttacc aatagcaaat
     3181 ggtactacgt ctggagcttt ttctttgatt tgtttcaaga ctggctcaag agtttcgtaa
     3241 gaagtaacac ctgaaatatc gataccatat ttggcaagga gagttccgtt gaaggcaaag
     3301 ttttgagatg atgctacgtt ggctgcaact ggtacagcgt aaatcttacc atttacagta
     3361 ttacccttga tataagctgg atcaagtgcc ttgtaaaggt ctttaccttc ttttttgtac
     3421 aattctgtca agtcagcata agcacctttt tgagcattta caatatagtt atctgcaaag
     3481 gcgatatcat agttttcacc agatgatgtg ataactgaca ttttcttacc atagtcaccc
     3541 cagccaaggt attggatatc caatttagca ccaacttttt cttcgatgat tttgttggca
     3601 tttgctaaca attcatccaa gttatctggt ttgtcaccga tttggtacat tttgataaca
     3661 ggtttgtcac ctgaatcagc agcttttttg ctgttacctg tcaagttgcc acaagcagca
     3721 agacctgcag ccaaagcaac tacactagca gatgcaaaag catatttttt ccagtttttc
     3781 atgataaaaa ctcctttttt tatttttaaa cttataaaca atgtaatgat cttaacttca
     3841 cgcaagggaa gtttggaaac aagtgctatt ctttcacacc accgatagtc aaacctttta
     3901 caaagtagcg ttggaagaat ggatacaaaa tcgcgattgg aagggttgct accacaacca
     3961 tggccatacg acctgtttct ttcggtagag caactcccag ttgaccagtc aagccgaccg
     4021 ctttggcaat gtagtccata ttttgttgga tttgcatgag caaatattgc aatggataca
     4081 agttatcact cttgatgtaa agaagggcgt tgaaccagtc attccagaaa ccaagagctg
     4141 tcaaaagcgt gatggttgcg atacctggta gtgacaatgg caaacagatt tggaagaaaa
     4201 tccgggcctc actggcacca tcgatacgag ccgattcgag aatggcttct ggaatggtct
     4261 tcttgaagaa ggaacgcatc aagatgatat tgaatggtga gagaagcatt ggaacaatca
     4321 aggcccaaac agtgtcacca agctgaagta cacgggtcac catgatataa cctggtacca
     4381 aaccagcgtt gaacaacata ctgagaagga cgaagatggt aaaaaatctg cgatacttaa
     4441 aggttgtccg tgaaatagcg taggcatagg ttgttgtgat aaagacattt gtcaatgtcc
     4501 caactacggt tacaaagaca gagatgaaga gggcttgtag gattttatcc ttaaactgtg
     4561 ccaaaaactc aaaaccgtct aagccaaatt gggatgggaa gaagctatag ccgtattgga
     4621 ggaggctttt ctcgtctgtc actgaaataa tgataacgaa tacaaaaggt aggatacaag
     4681 agagggcaat caaacccgaa atgatactga agaagatatc tgctttctta ctgaaggagt
     4741 gaatgccgac attatcaatt ttttcttttt taattttctt ttttgccata ttctcctcct
     4801 ttctagaaca aagctgagtt tggatcgact cgtcttgcaa gcaagtttga taggataacc
     4861 agaatcaaac caacaacgga ttggtaaaga ccggctgctg cagccatacc gatatctgct
     4921 gtctgagtca aaccattaaa gacatatacg tccaaaacgt tggttacatt gtaaagctga
     4981 ccagcattgt gtgggatttg atagaagaga ccaaagtctg cgcggaagat atttccgact
     5041 gcaaggatgg tcaatacagt tacaagcgga gtcaactgag gaatggttac gttgcgaata
     5101 cgttgccact tgctagctcc gtccactgtc gctgcttcgt agtaggttgg atcaattccc
     5161 atgatcgtcg catagtacat gacactgcta tatccaaagc ctttccaaat acctaggaaa
     5221 agtaggagat agggccagat gcccaggtca gcgtaaaaat tgacttcttt gagaccaaga
     5281 ctttccaata gatgattgaa caccccttta tcaatattta ggaaggcatc tgtaaagaaa
     5341 ctgatgataa cccaagacaa gaagtaaggg aacaacatag aagtttggaa aatcttcacc
     5401 attctcttag aacggagctc gctgaggata atggcaatcc ctacagatac aactaaacct
     5461 agaaagataa agccaagatt gtagaggaca gtatttcgtg tgataataaa ggcgtctctt
     5521 gaactaaata agaatctgaa attatcgagt ccgacccatt tactatttat gatactatct
     5581 atgaaaccat tactggtcat gtggtagtct ttgaaggcaa ccacgttccc aaatactgga
     5641 atgtaaaaga atagaatcaa ccagagtgtc cctggcaaaa ccatcaagag aaagatccag
     5701 ttgtctctca atgtttttga aaactttttc ataatttcct ccctttttat tttgatatcc
     5761 atctaaaaat tcttttttag acttttgata acgattacat tattagtata ctcctatttg
     5821 caggttaggt taaactccta attatagaaa aaactccaca aattatgtag cagatttaaa
     5881 actttatcac cactatcaaa caaatgtcct aaatcaattg tttattttat ctctattagc
     5941 ccagtgatgg cgtcactctg ttataagcat ccaacaacgg ggtatactga aaaatctcca
     6001 gactagggaa ctcagagata gttcctaatc tggagatttt taatatgtta ttaggcgttt
     6061 gctttcaact tagcaataac ctctttaaga ttatcaatca cctctgcttc agtatgctca
     6121 gagctttttc atctgccaag aacaaaactg ctttttgaag ttctttttga gagttttcaa
     6181 ggacatcctt atctactgtt tcaaggtttg agtctttaag aagtttactt aattccttgg
     6241 ctaatttctt gagtttgatt tgcagactca tcttctcctg ctgtttcttt gcccgctgtt
     6301 tgtcctccat ccttagttgc tgactggctt tccttaatgg actctaggga agcaatggca
     6361 tctttgactg tttgcaaaat atcacgtaaa ccttgctctg tcaaactatc atctgcaaaa
     6421 gctttcttag cctctgccaa aaccagacgt gctgaatctg tggtaggatt cgatacacct
     6481 gtcaatgatc tcaaaagatt ttctaaggtt tgagtctgct tactaatact agactaaaat
     6541 caaaaagcat tatataacag tgatatgaaa tcaactaaag aagaaatcca aactatcaaa
     6601 acacttttaa aagactctcg tacagctaaa tatcataaac gccttcaaat cgttctatag
     6661 taaaatgaaa caagaacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
     6721 ttta
//
LOCUS       DAVBNN010000083         6627 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBNN010000083 DAVBNN010000000
VERSION     DAVBNN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.083"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ847_001931"
     CDS             170..370
                     /locus_tag="VQ847_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051220.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ847_001932"
     CDS             412..816
                     /locus_tag="VQ847_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051221.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ847_001933"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ847_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3051222.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ847_001934"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ847_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3051223.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ847_001935"
     CDS             2697..4088
                     /locus_tag="VQ847_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3051224.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ847_001936"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ847_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3051225.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ847_001937"
     CDS             5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ847_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3051226.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT         2032 a         1214 c         1411 g         1970 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagtatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa
     6541 taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatgt
     6601 ctcaagtgat aaagtcaagt tagtgga
//
LOCUS       DAVBNN010000084         6297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBNN010000084 DAVBNN010000000
VERSION     DAVBNN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.084"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(58..384)
                     /locus_tag="VQ847_001938"
     CDS             complement(58..384)
                     /locus_tag="VQ847_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3051227.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
     gene            complement(351..635)
                     /locus_tag="VQ847_001939"
     CDS             complement(351..635)
                     /locus_tag="VQ847_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3051228.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            complement(908..1750)
                     /locus_tag="VQ847_001940"
     CDS             complement(908..1750)
                     /locus_tag="VQ847_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3051229.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1864..3255)
                     /locus_tag="VQ847_001941"
     CDS             complement(1864..3255)
                     /locus_tag="VQ847_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3051230.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3490..3867)
                     /locus_tag="VQ847_001942"
     CDS             complement(3490..3867)
                     /locus_tag="VQ847_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3051231.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4082..5059
                     /locus_tag="VQ847_001943"
     CDS             4082..5059
                     /locus_tag="VQ847_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3051232.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLTDKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYKTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5056..6138
                     /locus_tag="VQ847_001944"
     CDS             5056..6138
                     /locus_tag="VQ847_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3051233.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT         1895 a         1389 c         1058 g         1955 t
ORIGIN      
        1 tctgccactg atgcagtgaa atgtcaattt cttagacatt gtttactcct ttagttttta
       61 tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa aagttttttc
      121 tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta aattttctac
      181 caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg catagttctt
      241 atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ctatacttct tctgaaaaag
      301 ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg tcaagaaata
      361 cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt cataaccatt
      421 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
      481 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
      541 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
      601 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
      661 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
      721 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
      781 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
      841 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
      901 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
      961 ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
     1021 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccagacca
     1081 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
     1141 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
     1201 agtaagctac gacttgttct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
     1261 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
     1321 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
     1381 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
     1441 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
     1501 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
     1561 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
     1621 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
     1681 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
     1741 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
     1801 agtagtacta tattctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
     1861 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
     1921 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
     1981 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
     2041 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
     2101 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
     2161 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
     2221 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
     2281 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
     2341 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
     2401 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgatg
     2461 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
     2521 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
     2581 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
     2641 gtcagagaag ttttttacaa tctgctcact ctggtcttga tctatttttt tatcctctat
     2701 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
     2761 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
     2821 agtctcttca atcttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
     2881 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
     2941 ttctagcttg tccttaacat cttgatttat cagctcccta acagaggaaa tcactttctc
     3001 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
     3061 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
     3121 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
     3181 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
     3241 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
     3301 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
     3361 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
     3421 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
     3481 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
     3541 atcgacaatt gcgatagcgt atactagtgc gatttgtttg tagctctggt gggtatcacc
     3601 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
     3661 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
     3721 atctaactcc gccaagacgt ctatactagt atagaaatct tgcgctgagt agggcatgga
     3781 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
     3841 catatcgcgg ataaattgac aaatcattag ttgggctgat acctggatgt ctgagaatcc
     3901 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
     3961 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
     4021 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
     4081 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
     4141 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
     4201 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
     4261 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
     4321 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
     4381 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
     4441 tcgtaattac cacgagaaag cctttactac tatcaaaaac tttttaacag ataagcaagt
     4501 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg
     4561 acaaacacca aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat
     4621 ttatcccctc tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc
     4681 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
     4741 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
     4801 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
     4861 ccaccaagga aatcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga
     4921 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctaca aaacttggct
     4981 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
     5041 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
     5101 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
     5161 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
     5221 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
     5281 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
     5341 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgtct taaaaagggg
     5401 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
     5461 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
     5521 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
     5581 atgagtgcca cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat
     5641 ctctctgacc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
     5701 cgagtggata tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
     5761 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattgact
     5821 gtttccctcg ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa
     5881 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
     5941 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
     6001 gctggtcgta ctggccgtat aggcaaggaa ggatatgtta ttactctcgt cactcatcca
     6061 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
     6121 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
     6181 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
     6241 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgatt
//
LOCUS       DAVBNN010000085         6205 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBNN010000085 DAVBNN010000000
VERSION     DAVBNN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6205
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.085"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ847_001945"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ847_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ847_001946"
     CDS             1555..2427
                     /locus_tag="VQ847_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3051234.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ847_001947"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ847_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3371
                     /locus_tag="VQ847_001948"
     CDS             3060..3371
                     /locus_tag="VQ847_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051235.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3375..4091
                     /locus_tag="VQ847_001949"
     CDS             3375..4091
                     /locus_tag="VQ847_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3051236.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4221..5036)
                     /locus_tag="VQ847_001950"
     CDS             complement(4221..5036)
                     /locus_tag="VQ847_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3051237.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5033..5938)
                     /locus_tag="VQ847_001951"
     CDS             complement(5033..5938)
                     /locus_tag="VQ847_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3051238.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         1960 a         1073 c         1249 g         1923 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aacgcgaaga attgcgtcag attatcacaa ctatctttga acaaaagatg aataagcata
     3361 gtattaagta gagaatgaaa aaatatttta ttggcggttt gggaagcaat gcctatcata
     3421 gcaaggattt tcttcaagaa ctagattcgc aggtctattt tctaaatcca tatgaaaagc
     3481 atcttcgaga tgaaacagaa ttgaaatcat ggtttaaaaa tgagattgta gaggaagaat
     3541 ctatctgtct gataggtcat tctattggag gcgatttagc tcgttatttc gcatcggaat
     3601 ttgaagaagt aaagaaactg attcttttgg atggtggcta tctagattta gataagattt
     3661 tacctttgga tacagagtta gaggaaacta aaaattatat caaatctcaa attatttcgg
     3721 acttagatgt tcttacttct aaagaaaaat ctgaagcaaa gcattggtca gaaaatatgg
     3781 agaaagctgt aagacagtcc tatcactgga atgttgagta taatagatat gagttggcta
     3841 taaattatga aaatatagaa gcgatactcc gcctacggag aaaaatacaa gcttttaaga
     3901 gagaagtggg agataccttg tttattagtc ctcgctatcc taatgaagct acatggagag
     3961 aggaagccct aaaagaattg ccagactatt ttgatactat ttttttagaa aactttggcc
     4021 atgagcttta tactcaagca cctaaagaaa tcgctagtct aatgaatgag tggctcgctt
     4081 attttctatg agctacttgt attgctggaa atggtataag atgaaaatct acaagtcact
     4141 aattttcata taaccaaaaa acgaacaggc tctttttctg ttattcagaa gagaacttgt
     4201 tcgtttttat cttgattttc ttaaaaagct ctatatacat agggattttc tggtttatcg
     4261 actttggtaa agctgtcgat ttccaaggtt ggaaggtttt gtttgagttc tttatggtag
     4321 tgattgacca gttttccttt ggctgaaatc caagtgttgt tttcatactg ccgggtattg
     4381 cccttggtca gcaatccata gacaccagaa tctgcgatgc agtgaataat gccgaagcgg
     4441 aacagaaatt ggctattggc atgactgggg tcattataga caaagcctgt gaactggatt
     4501 gtcttaccct caaattcatc tggatagtcg tagatagcct ccatgacctc catatagttt
     4561 tcattagtga tctgaatact atcttgggat aagtatttat ccgccgccgt tcgcatttcc
     4621 ttttcatagg ctgattttga aaaataagaa ctggtatctg gtttcaaata ttggcttgtc
     4681 gtcccttcgc ttgtctgaat ggctagatcc gttccttccg atagggggaa atgataacct
     4741 ttagcagaaa cggtctgaga atccaagcta acagttggga aagttaagcc gatgacaagt
     4801 ggaatagcca gaagagaaat actcgtcatc ttggctaatc ggctgttcag atgactgtgg
     4861 gttttgactt gcttcatcca gatatacaat tgaacgatag ccaagataaa agaaagcacc
     4921 atggagatat aggccagata ggaatagtgc atgttgatgt actggtttag tttgcccgac
     4981 agatggaggt aaatagtcag ttcaaaatag ccagctaaaa ctaaaaatcg aatcatagga
     5041 tgactccaat caagagagaa tagactaaga cgacaagagt tacaattgtt atgaagtgac
     5101 tgataaatcg tgctttcaag taatttttca tcatgagaat atttttgata tccagcattg
     5161 gaccaatgac gagaaaggcc agaactggtg ccaaaccgaa actcgagaga agagaagcac
     5221 ctataaaggc atccgcctca ctacagagcg aaagaagaaa ggctaaaatc atcaagagca
     5281 ggatggcaaa aagaggggtc gcactgatag aggtcagaat ccgagtcgga acgtagacct
     5341 gtattataga agcaaagagg cagccaaata ccaaataacg ccccgtatca aaaaattcat
     5401 caatggcctg cacaaagact tgaaaaactt tttttgcaga actcaagtaa gaaaaatcat
     5461 gctcatgaca agccagacga ttttctttct gaatcggttc ttgccagaaa aatcctagaa
     5521 aaattcctag tattacagcc acaagaatgg aacccagagc tcgtaatagg gcgacatgga
     5581 aggagttgcc aaaggcagaa taggtcgcaa aaagaacaat gggattgata acaggtgctg
     5641 tcacaagaaa aggaacggcc gtgtaacttg gaaccttttt ttccagaaaa cgattgatga
     5701 tggggacgat tccacattca caagaaggga aaaacatacc gacgaaggtc ccaaaaaaga
     5761 ttctccccca acgatttcga gggagaaaat gataaacctt gtcaggtgtg atataaactt
     5821 caatcagccc tgagacaatg cttcctatca gaacgaaggg aagggcttca atgataatgg
     5881 agagaaaaat ggctccagtt tgaagtacac tagatgggag ttgttgaaaa gcagtcatct
     5941 agtttttctt ttctgctttg gcttttttct ctttgtcatc agggaaagta acttgtttca
     6001 aatcagggag tttagcaaac tcttcaaaca tcttgtccaa gtcgtctcgt tttgtaaatt
     6061 ttacagccat aggtgtacct cgattctaaa ttctacctct attatactat tattttgcgg
     6121 aaaagggagt tttttaattt gttttcgata gttgatactc ttcgaaaatc tcttcaaacc
     6181 acgtcagctt cgccttaccg tagta
//
LOCUS       DAVBNN010000086         5194 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBNN010000086 DAVBNN010000000
VERSION     DAVBNN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.086"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(134..268)
                     /gene="rpmH"
                     /locus_tag="VQ847_001952"
     CDS             complement(134..268)
                     /gene="rpmH"
                     /locus_tag="VQ847_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3051239.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(413..1627)
                     /locus_tag="VQ847_001953"
     CDS             complement(413..1627)
                     /locus_tag="VQ847_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3051240.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1783..2076)
                     /locus_tag="VQ847_001954"
     CDS             complement(1783..2076)
                     /locus_tag="VQ847_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051241.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            2238..2690
                     /locus_tag="VQ847_001955"
     CDS             2238..2690
                     /locus_tag="VQ847_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3051242.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2725..4113)
                     /locus_tag="VQ847_001956"
     CDS             complement(2725..4113)
                     /locus_tag="VQ847_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3051243.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            4179..5141
                     /locus_tag="VQ847_001957"
     CDS             4179..5141
                     /locus_tag="VQ847_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3051244.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         1508 a         1204 c         1017 g         1465 t
ORIGIN      
        1 cagaggtgta ctattctagt ttcaatctac tataacatcg cttccgaatc catttgcatc
       61 tactgaactt ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata
      121 gaattcgttt ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata
      181 cgcgacgacc atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa
      241 gtttacttgg ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt
      301 ttagccggct ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc
      361 acttttgtca atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac
      421 gatactgttt caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag
      481 gaaggtaaac gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca
      541 agagaacctt ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt
      601 acatattgcg gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca
      661 aacctggaat atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac
      721 caggaagaag caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt
      781 gggccaaaac gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc
      841 ccttaacatg agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc
      901 ggtgggattt tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca
      961 caggcgtatg cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa
     1021 tcaaatcgtt ttgacgggca atctcaataa tccccagcaa gagttcctta ggataaaggg
     1081 ctccagttgg gttatttgga ttgataagga caattgcctt ggtattggaa gtgatttttg
     1141 acttgatatc gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg
     1201 catttcctcc agctaggctg acagccgccg tccatagagg atagtctggc attggcacta
     1261 agacctcatc cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac
     1321 catttccaag gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact
     1381 gcatgatggc cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac
     1441 gcgcattcat aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg
     1501 gatttcctgt attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt
     1561 ccaatacagg accacggata tcataagcaa catgctctaa cttactagac ttgttatatt
     1621 ctttcatctt gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg
     1681 cgacaagttt actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg
     1741 aggttaagaa cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa
     1801 acctagaaaa agcaagccta gaaaggagtc ataaagaaga ttaaacatga ggaaaagccc
     1861 ccatatcatc aagtaatccc aacgcccact tcgttttgca actagaaata agattagatg
     1921 gtagagtaca tgaaagacta aaaatccaat aaaacctgga taaataagcg gtaccaaact
     1981 ctctaattgc cagatcatga tcacttctac caagactgaa actaggataa ttccataata
     2041 caggaaattt gatttttgaa aagagttttt catcattctc ccttccttca cttctttcct
     2101 gctatccttt cttttatttt atcatatatt tatatagatt ttaagcccta atattctttt
     2161 gaaaaatact ttttttgctt tacttctata gtgaaaaggt ttacaattat agtaagaaaa
     2221 tttcaggagg tttcattatg gcacaacgtt accaaaatat catggtcgca atcgatggtt
     2281 ctaaggaagc ggacttggct tttgtcaagg gagttcattc tgctctacga aacgacgcta
     2341 aactcaccat cgtacatgtc attgacacac gcgctctcca aagcgtatcc acctttgatg
     2401 ctgaagttta cgaagaactc caagtcgacg ctgaaagtct gatgaaagag tacgaaaaac
     2461 gtgctaaaga tgctggggta gcagatgttc atatcgtcat tgaaatggga aatccaaaga
     2521 ccctgctagc acgtactatt ccagatgccg aggaagtgga cctcatcctc gttggcgcaa
     2581 ctggtctcaa cgcctttgaa cgcctcttag tcggctcttc atctgaatac atactccgcc
     2641 atgctaaggt cgatttgctg gttgtgagag aacaagaaaa aaccttataa tcacaaagaa
     2701 aaggagcccc tagctccttt ttgtttacga tttatttctc tctttatggc gttcgtaagc
     2761 cttgagctgg cgctgcagtt cctttttaat agcaggttct ggagcatatt tttcttccca
     2821 attatctggt tttaagattt tatgggtcac tggatcaaaa tgagccttgc catctggaaa
     2881 aattttcccc atattggcct gatggacaat atcaaaaata cgttctgggt ccacccccat
     2941 caagacaaaa ctgccgtagg tgaagtaaag cgtgtcaatc aaggcatcca cttgccctat
     3001 caaatcttgc tgagcaggtg tcttcttggc tactttacct gctgccttat caagggcctg
     3061 atgaagttgc gatacagctt gaccaaaatc ttcttcagaa ggactggctg ctcgaacaaa
     3121 ctccaccaat tcttctattt taaaaccagc cctatgggtt gcaccctcta aatcccaagc
     3181 tcgaggttct tcttgggttc gttcatccat catgtggtgg aaggtcttga ccttattgaa
     3241 atgatagtca cggctgacaa agactttttc tgaagacaaa acaccaaaat gttccaaggc
     3301 cttgtggatc ccatcttgtt gattgctagt ggtaatgtgc ttggcagctt ccttgacact
     3361 gctactacca tttcccatag cgaccgacat accgacgcca gccagcattt caaggtcatt
     3421 atctgagtca ccaaaagcca tgacttggtt gaggtcaaag ccatattctt tcccaactcg
     3481 gcgaatgcct tctaatttag aatttccctg attgatgaca tccgatgcaa aaggattgct
     3541 acgtgtcaat ttcaagtctt caaaatcagc tgccgccttc tcagattctt ctggtgtcat
     3601 cagcatcaaa acttggtaga taggctgatt catcaggtga agcaggtcct cttccttttg
     3661 gggaacaacc ttgctgacca tgcgattaaa agactgactc accgtccgag ttaaaacaga
     3721 gggaacgaag cgactaattc gttgggaaaa agaacccaga ccaaaggaca tgattttaga
     3781 acccaacatg gcatccttgg tccctagagc aatctccgtg ccctcttttt tagcatagct
     3841 aattagatgg cgcaaatgta acttggaaat agggctcgtg aacaagactc tgtctttact
     3901 aaagatatac tggccattat aggttaccgc aaaatccaga tccaaatcgt ccatcaattc
     3961 cttaacaaaa aaaggtcctc gtcctgtcgc tacgccaact agtacccctt gttctttgac
     4021 aatcttaatc gcgtccttag tggatttcaa aacactcttg cgattgttga ccaaggttcc
     4081 atcgatatca aaaaaaacag ctttgacttc catcctattc caatctcccc ttttgtgata
     4141 caatgattat accacatttc agaaagagtt agtaaatcat gcctaagaaa atccttgttt
     4201 tacatacggg tggaactatt tccatgcagg ccgatgcttc tggcgctgtt gtgacgagtt
     4261 cagataatcc catgaaccat gtgtccaacc cacttgaagg aatccaagtc cacgccttgg
     4321 acttttttaa ccttccaagt ccccatatca aacccaaaca tatgctggtc ctctaccaga
     4381 aaattaaaga ggaagcagat aactacgatg gagtggtgat cacacacgga accgatactt
     4441 tagaggaaac agcctatttc cttgatacca tggaagttcc ccatatgcct atcgttctaa
     4501 caggagccat gcgtagctcc aatgagctcg gtagtgatgg tgtttataat tacctaagtg
     4561 ctttacgagt ggccagcgat gacagggctg ctgacaaagg agttttggtc gttatgaacg
     4621 atgaaatcca cgctgccaag tatgtcacca aaacacatac gactaatgtc agcaccttcc
     4681 agactccaac acatggcccc ctcggtctca tcatgaaaca ggaaatcctc tacttcaaaa
     4741 cagctgaacc tcgtgttcgc tttgaccttg atcacataca aggtttagtc cctatcatct
     4801 cggcttatgc tggtatgaca gatgagctga ttgatatgct ggatttagaa cacttggacg
     4861 gtttgattat ccaagccttc ggagctggta atattcccaa agaaacggct caaaaattag
     4921 aaagccttct gcaaaaagga atcccagtcg ctctggtatc acgatgcttt aacggtattg
     4981 ccgagcctgt ttatgcctac cagggtgggg gcgtacagtt gcaaaaagca ggcgttttct
     5041 ttgttaaaga actcaacgcc caaaaagctc gcttgaaact cctcatcgcc ctcaatgccg
     5101 gactaacagg acaggctttg aaagactata tggaaggcta atactcttcg aaaatctctg
     5161 caaaccacgt cagcgtcgcc ttaccgtatg tatg
//
LOCUS       DAVBNN010000087         5118 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBNN010000087 DAVBNN010000000
VERSION     DAVBNN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.087"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            251..1796
                     /locus_tag="VQ847_001958"
     rRNA            251..1796
                     /locus_tag="VQ847_001958"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1848..1920
                     /locus_tag="VQ847_001959"
     tRNA            1848..1920
                     /locus_tag="VQ847_001959"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1881..1883,aa:Ala,seq:tgc)
     gene            2045..4946
                     /locus_tag="VQ847_001960"
     rRNA            2045..4946
                     /locus_tag="VQ847_001960"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5023..>5118
                     /gene="rrf"
                     /locus_tag="VQ847_001961"
     rRNA            5023..>5118
                     /gene="rrf"
                     /locus_tag="VQ847_001961"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1452 a         1033 c         1497 g         1136 t
ORIGIN      
        1 gtatgttgcg gttggaacac ttgatgaaaa aaagtttaaa aaagcttaaa aatcttcaaa
       61 aaagtgttga caagcgaaag cggctgtgat atactaatat agttgtcgct tgagagaagc
      121 gagtgacaaa gacctttgaa aactgaacaa gacgaaccaa tgtgcagggc gctacaacat
      181 aagttgtagt actgaacaat gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag
      241 aactcaaact tttaatgaga gtttgatcct ggctcaggac gaacgctggc ggcgtgccta
      301 atacatgcaa gtagaacgct gaaggaggag cttgcttctc tggatgagtt gcgaacgggt
      361 gagtaacgcg taggtaacct gcctggtagc gggggataac tattggaaac gatagctaat
      421 accgcataag agtagatgtt gcatgacatt tgcttaaaag gtgcacttgc atcactacca
      481 gatggacctg cgttgtatta gctagttggt ggggtaacgg ctcaccaagg cgacgataca
      541 tagccgacct gagagggtga tcggccacac tgggactgag acacggccca gactcctacg
      601 ggaggcagca gtagggaatc ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg
      661 agtgaagaag gttttcggat cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg
      721 gaaagttcac actgtgacgg tatcttacca gaaagggacg gctaactacg tgccagcagc
      781 cgcggtaata cgtaggtccc gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg
      841 cggttagata agtctgaagt taaaggctgt ggcttaacca tagtaggctt tggaaactgt
      901 ttaacttgag tgcaagaggg gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata
      961 tatggaggaa caccggtggc gaaagcggct ctctggcttg taactgacgc tgaggctcga
     1021 aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgctgtaaa cgatgagtgc
     1081 taggtgttag accctttccg gggtttagtg ccgtagctaa cgcattaagc actccgcctg
     1141 gggagtacga ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca caagcggtgg
     1201 agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac atccctctga
     1261 cgactctaga gatagagttt tccttcggga cagaggtgac aggtggtgca tggttgtcgt
     1321 cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc tattgttagt
     1381 tgccatcatt tagttgggca ctctagcgag actgccggta ataaaccgga ggaaggtggg
     1441 gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta caatggctgg
     1501 tacaacgagt cgcaagccgg tgacggcaag ctaatctctt aaagccagtc tcagttcgga
     1561 ttgtaggctg caactcgcct acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc
     1621 cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga gagtttgtaa
     1681 cacccgaagt cggtgaggta accgtaagga gccagccgcc taaggtggga tagatgattg
     1741 gggtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa
     1801 ggataaggaa ctgcgcattg gtcttgttta gtcttgagag gtcttgtggg gccttagctc
     1861 agctgggaga gcgcctgctt tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca
     1921 ttggtgagag atcaccaagt aatgcacatt gaaaattgaa tatctatatc aaatagtaac
     1981 aagaaaataa accgaaaacg ctgtagtatt aataagagtt tatgactgaa aggtcagaaa
     2041 ataaggttaa gttaataagg gcgcacggtg gatgccttgg cactaggagc cgacgaagga
     2101 cgtgacaaac gacgatatgc cttgggtagc tgtaagtaag cgatgatcca tggatttccg
     2161 aatgggggaa cccaacaggt aatacctgtt acccacatct gttaaggatg tgaggaggaa
     2221 gacgcagtga actgaaacat ctaagtagct gcaggaagag aaagcaaaag cgattgcctt
     2281 agtagcggcg agcgaaacgg cagaagggca aaccgaagag tttactcttc ggggttgtag
     2341 gactgcaatg tggactcaaa gattatagaa gaatgatttg ggaagatcag ccaaagagag
     2401 taatagcctc gtatttaaaa tagtctttgt acctagcagt atcctgagta cggcgggaca
     2461 cgtgaaatcc cgtcggaatc tgggaggacc atctcccaac cctaaatact ccctagtgac
     2521 cgatagtgaa ccagtaccgt gagggaaagg tgaaaagcac cccgggaggg gagtgaaata
     2581 gaacctgaaa ccgtgtgcct acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt
     2641 ttgtagaatg aaccggcgag ttacgttatg atgcgaggtt aagttgaaga gacggagccg
     2701 tagggaaacc gagtctgaat agggcgcctt agtatcatga cgtagacccg aaaccatgtg
     2761 acctacccat gagcaggttg aaggtgcggt aagacgcact ggaggaccga accagggcac
     2821 gttgaaaagt gcttggatga cttgtgggta gcggagaaat tccaaacgaa cttggagata
     2881 gctggttctc tccgaaatag ctttagggct agcgtcgaca ttagagattc ttggaggtag
     2941 agcactgttt gggtgagggg tccatcccgg attaccaatc tcagataaac tccgaatgcc
     3001 aatgaattat ggtcggcagt cagactgcga gtgctaagat ccgtagtcga aagggaaaca
     3061 gcccagacca ccagctaagg tcccaaaata attgttaagt ggaaaaggat gtggggttgc
     3121 acagacaact aggatgttag cttagaagca gctattcatt caaagagtgc gtaatagctc
     3181 actagtcgag tgaccctgcg ccgaaaatgt accggggcta aaacaattta ccgaagctgt
     3241 ggataccttt ataggtatgg taggagagcg ttctatgtgt gatgaaggta taccgtgagg
     3301 agtgctggaa cgcatagaag tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc
     3361 ctgtccaccg taagactaag gtttccaggg gaaggctcgt ccgccctggg ttagtcggga
     3421 cctaaggaga gaccgaaagg tgtatccgat ggacaacagg ttgatattcc tgtactagag
     3481 tatgtagtga tggagggacg cagtaggcta actaaagcag acgattggaa gagtctgtct
     3541 aagcagtgag gtgtgaattg agtcaaatgc ttaattctat aacattgagc tgtgatgggg
     3601 agcgaagttt agtagcgaag ttagtgacgt cacactgcca agaaaagctt ctagcgttta
     3661 aacatactct acccgtaccg caaaccgaca caggtagtcg aggcgagtag cctcaggtga
     3721 gcgagagaac tctcgttaag gaactcggca aaatgacccc gtaacttcgg gagaaggggt
     3781 gctgacttta agtcagccgc agtgaatagg cccaagcaac tgtttatcaa aaacacagct
     3841 ctctgctaaa tcgtaagatg atgtataggg ggtgacgcct gcccggtgct ggaaggttaa
     3901 gaggagtgct tagcgtaagc gaaggtatga attgaagccc cagtaaacgg cggccgtaac
     3961 tataacggtc ctaaggtagc gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc
     4021 gtaatgattt gggcactgtc tcaacgagag actcggtgaa attttagtac ctgtgaagat
     4081 gcaggttacc cgcgacagga cggaaagacc ccatggagct ttactgcagt ttgatattga
     4141 gtgtctgtac cacatgtaca ggataggtag gagtctaaga gatcgggacg ccagtttcga
     4201 aggagacgct gttgggatac tacccttgtg ttatggccac tctaacccag ataggtgatc
     4261 cctatcggag acagtgtctg acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa
     4321 cggaggcgcc caaaggttcc ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat
     4381 aagggagctt gactgcgaga gctacaactc gagcagggac gaaagtcggg cttagtgatc
     4441 cggtggttcc gtatggaagg gccatcgctc aacggataaa agctaccctg gggataacag
     4501 gcttatctcc cccaagagtt cacatcgacg gggaggtttg gcacctcgat gtcggctcgt
     4561 cgcatcctgg ggctgtagtc ggtcccaagg gttgggctgt tcgcccatta aagcggcacg
     4621 cgagctgggt tcagaacgtc gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa
     4681 tttgagagga tctgctccta gtacgagagg accagagtgg acttaccgct ggtgtaccag
     4741 ttgtcttgcc aaaggcatcg ctgggtagct atgtagggaa gggataaacg ctgaaagcat
     4801 ctaagtgtga aacccacctc aagatgagat ttcccatgat tatatatcag taagagccct
     4861 gagagatgat caggtagata ggttagaagt ggaagtgtgg cgacacatgt agcggactaa
     4921 tactaatagc tcgaggactt atccaaagta actgagaata tgaaagcgaa tggttttctt
     4981 gaattgaata gatattcaat tttgagtagg tattactcag agttaagtga cgatagccta
     5041 ggagatacac ctgtacccat accgaacaca gaagttaagc cctagaacgc cggaagtagt
     5101 tgggggttgc cccctgtg
//
LOCUS       DAVBNN010000088         4640 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBNN010000088 DAVBNN010000000
VERSION     DAVBNN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.088"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..132)
                     /locus_tag="VQ847_001962"
     CDS             complement(<1..132)
                     /locus_tag="VQ847_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3051245.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     "
     gene            complement(512..1372)
                     /locus_tag="VQ847_001963"
     CDS             complement(512..1372)
                     /locus_tag="VQ847_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3051246.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1388..2665)
                     /locus_tag="VQ847_001964"
     CDS             complement(1388..2665)
                     /locus_tag="VQ847_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3051247.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2658..3209)
                     /locus_tag="VQ847_001965"
     CDS             complement(2658..3209)
                     /locus_tag="VQ847_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3051248.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3225..4484)
                     /locus_tag="VQ847_001966"
     CDS             complement(3225..4484)
                     /locus_tag="VQ847_001966"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3051249.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         1438 a         1064 c          741 g         1397 t
ORIGIN      
        1 tccacctttt gcatgtttaa gttgataagc tgtttttaat acagctaaca tctcttcaaa
       61 agtggtacgc tgaacatcaa caagacgctt aaatcgtgca tcagttagtt gtttacttgc
      121 ttcatcattc atagaactac tataccatgt tttgtttcgc aggaagtata atataaaaaa
      181 ataaatttaa gattggcaat acgaacgtta aacagaattc catttctctt tttagaatca
      241 aaacgacaat attgtggaat ctctacagga acaatagact gcgacactaa aatatcctcc
      301 cttagtttta ctttactaat agtatatagg aggagagccc tgaatcctag accctttgtt
      361 atgatgcgct tacaaacaga gttggaaaaa atcttaaaag cagaaaaacg catgatatca
      421 gcccctaaca cttgatacaa tgcgttttat tatgaaaaga tctactggat tttttatcaa
      481 aataaacttc cagtagtctt ttcacttttt attaataagt tccttcttca ccttggctag
      541 tcaagataac aggtccatct ttcgtaatga caaattggtg ttcatactga catgacaatc
      601 caccgtcaat ggtcttatgc gcccaaccag ttttcatatc tgtatcaatt tcccaatcgc
      661 ctgtattgat cattggttca atggttaaga ccattccttc acgaagacgg agtccacgac
      721 ctgcaatacc atagttagga accattggtt cttcgtgcat agttgggcca acaccatgac
      781 caaccaaatc acgcactaca ccgtaaccac gactttcagc gtattcttga atagccgcac
      841 cgatatcacc gatacgattt ccaacaacag cttgctcaat acccttgtac atagcttctt
      901 tggttacatc catcaagttt ttgacttctt cggacggtgt accaacagca taagcccaac
      961 atgagtctgc taaaccacca gaatagctct gagtatattt tttcatttgt tcaacattgt
     1021 tgaagtttaa ttttgagaca ttcaggtcag atttagcaat gggacctccc aaaaccatat
     1081 caactttgag caaatcacca tctttcaaga tataatgacg agggaaagcg tgagccactt
     1141 catcgttaag agagcaacag gtagcataag gatagtccat catggcaccg tcaaccccaa
     1201 tctgaagtgg aaggaaattt tcttctttac aacgacggcg gacatattct tcaacttccc
     1261 acatatctac gcctggctta atcaaatcac gtaagcctat atgaatactt gctagaaaat
     1321 caccagcctt gtccatagct tcgatttcac gagctgattt taatgttatc atcttttctc
     1381 ctagtttcta attaatttta acagtcacat ttgcttttga aacaatctgg tgaccatgat
     1441 aaatatcgta atcaattata gctgaccgtc tcgtatgatg aataatccgt gcctgaatgc
     1501 gcaatatatc atctatctga acagcctgca aaaagtagat cagcatctgc tcgataatga
     1561 gattgcgacc actattaaca actaaatctt gggtcatgtg ggtcagaatt tctgccaata
     1621 caccattagc caaaactcca tttttttcta gcataaaggg ttccactgta atgactactt
     1681 catcatggtg ataagagagc ttttgtccaa tctgctcaga aaaagttggt agagccgaaa
     1741 cttgggaacg gctcatcttc tccatgacat ctcgtcgcgt cacaacgcca agcaaagttt
     1801 gattgcttcg aacaactggt accatttcaa agtcttctgc gatcatccgt tgactcacat
     1861 tggcaatatt tgtcgataat ccaaccaaaa atagactacg agacataacc ttatcaattg
     1921 tcgtgcttgg tgatttatca ccagcgtctc tcatggttac aacgccaaca acgacctgat
     1981 gttgattgat aacagggaaa cggctgctac gattcttacg aaccaagtcc aaataatctt
     2041 taactgtatc tgtctctctc agaaaaccat actcatgact agggcgataa agtttctcaa
     2101 ctgtcagaat atcagtcttg atttggacat ttgacaaggc tttattgatc atggtcgcga
     2161 cggtaaaggt atcatgctta cttcttagaa caggaattcc tttttgattg gccagtttaa
     2221 gcacatcatc atgaacctga aatccccctg taaccagaac tgcattttca ttttccaagg
     2281 ctagcaactg aatacgggtt cggtctccga caatcaagag ccccccatca tgaaggtaag
     2341 acaagatatt ttgttcagtc atggcaccaa ttgaaaactt actaaattct ctctctaaac
     2401 cttcttgccc agccagaacc tcagaagaag tcacttctgc aatttcagca aacgttaatc
     2461 tctctatagc aactttctgg gatttaacac gaattgttcc acttctagga cgggtctcca
     2521 caattccacg gttttcagct tctttaatag cccgataggc tgttccatca ctaactccta
     2581 gatgattcga aatgctacga acactgaccc ttttacctac tggtaattcc tccaaatagc
     2641 ttagaatttc ctgatgctta ctcattgaac tctcctttta cataccgaaa ttcaagataa
     2701 tcccgcattt ttcttgtgta acgatcactt cccttaaact gacggaacaa actaaatcca
     2761 gacttaagag caactctttg gctagcttca ttttcaaggt gggtaatgat agataattgt
     2821 tttaagccaa attcctcaaa agaaagctga caaatttttc taacaacctc tgtcataaat
     2881 ccttgcgacc aagcatcttt tctcaaaaaa tagccaagct cagcttcttt tttgatttca
     2941 tctaacttct caaatttaat agaaccaatc atttgttgat ttttctggtc acaaattgcc
     3001 cacactccca aaggggactt cataaagtaa ttggccagtg catattgact ttcttccaga
     3061 cttgcctgcg ttgggaaaat aaattgaaga ttttctggat ttgaagctat ctcgcggaag
     3121 tcctgactat cactaaaaaa gaaaggacgc aaatacaagc gatccgtttc aaaaaaagaa
     3181 aacattgcta atttggtcca aatattcata aacacctcta cggtttaatc ctcaacaagt
     3241 ctaatatccg ctcctaaatt acgtaatttt tcgataatat cagaataacc acgtaagata
     3301 aactcgatat tggtaatttc agttttacct tcagccataa gcccagcaat gactagtgca
     3361 gccccagctc ttaagtcggt cgctttaaca ctggccccac gtaaatcacg tccacccgtg
     3421 tacaaaatat gaccatttgt tgtcgaaata tccgcatcca tctttgctag ttcaaaaaca
     3481 tgatttacac gtttttcgta aatcgtatcg acaattgtac cacgaccatt cgctcttagt
     3541 aaaagagggg taagcggttg ttgcaaatca gttgcaaagc ctgggtaagg agctgtctta
     3601 atattgattg ctttcaaatt agactgttcc tcgacaaaaa tgctgtcttc agatacagtc
     3661 attctcactc ccatttcttc caacttagca ataaaccctt ccaggtgttc gtaaagaaca
     3721 ttatttatac gaattccttt accaactgca gcagctaaag atatatatgt tccagcttca
     3781 atgcggtctg gaatcacctg atgacgtgtc ccatgtaatc tttcaacacc atcaataatg
     3841 atgatattag ttcctgcccc acggatatgg gcacccatat tattcaagag agtagctaca
     3901 tcaataatct caggttcacg ggctgcattt tcaataatag tacgaccatt tgctttaacc
     3961 gcagcaatca tcgtattaat cgttgctccc acactaaccg tatccatgta aatacttgca
     4021 ccatgaagtc ctgtatcttt agcagataac ttcatgttat ctccctcgta gctagcagtg
     4081 gcacccatag cttcaaacgc cttaaggtgt aagtcaatcg gacgaggacc aagatcacat
     4141 cctcccggta gaccaactgt cgcttcacca aaacggccta agaggctccc ataaaaatag
     4201 taagatgcac gaagactgtt aattttacca taaggcattg gaatattttg aacacctctt
     4261 ggatcaatct ccaagacatc gtcataacgc ttaacagtag ctcccatcaa ttccatgatt
     4321 tcgacaagac tggctacatc cgaaatatct ggaacacaat ccaaagtcac cacatcatca
     4381 gccaagataa tagctggaat taaggccaca acactatttt tagcaccact aatagtaatt
     4441 tcaccttgca gtggtaatcc accattgata acaatttttc tcattctaag ttttcaatac
     4501 tctttcaaga tttctaataa ggtcttcaaa ataaagtata tcataaattt atcctttttt
     4561 ccatcctttt caattttatt ggataaatca gagttgacga gttagtaact gaattactaa
     4621 tactcaataa aaatcaaaga
//
LOCUS       DAVBNN010000089         4531 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBNN010000089 DAVBNN010000000
VERSION     DAVBNN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4531
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.089"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..283
                     /locus_tag="VQ847_001967"
     CDS             <1..283
                     /locus_tag="VQ847_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3051250.1"
                     /translation="YNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDT
                     WYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            684..1805
                     /gene="mnmA"
                     /locus_tag="VQ847_001968"
     CDS             684..1805
                     /gene="mnmA"
                     /locus_tag="VQ847_001968"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3051251.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1946..2401
                     /locus_tag="VQ847_001969"
     CDS             1946..2401
                     /locus_tag="VQ847_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3051252.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2411..4324
                     /gene="mnmG"
                     /locus_tag="VQ847_001970"
     CDS             2411..4324
                     /gene="mnmG"
                     /locus_tag="VQ847_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3051253.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1309 a          919 c         1105 g         1198 t
ORIGIN      
        1 atacaacggt tcatggtact acctaaacgc taacggtgct atggcaacag gttgggctaa
       61 agtcaacggt tcatggtact acctcaacgc taacggttca atggcaacag gttgggtgaa
      121 agatggagat acctggtact atcttgaagc atcaggtgct atgaaagcaa gccaatggtt
      181 caaagtatca gataaatggt actatgtcaa tggcttaggt gcccttgcag tcaacacaac
      241 tgtagatggc tatgaagtca atgccaatgg tgaatgggtt taagccgatt aaattaaatc
      301 atgttaagaa catttgacat tttaattttg aaacaaagat aaggttcgat tgaataaatt
      361 tatgttcgta ttctttaggt acctatctta tgatttcagg aaatgtcatt aaaaaaacga
      421 ctccttttct ctaacttgaa aaatagatta gagaaaatgg gttgttttat ttattatagt
      481 tatttgaatg aagataagaa gaaggtatac tcacatcatt cacataatct gtatattgac
      541 tataagtttt aaaaaacaat ttttaagctc ttccttgtct tctctaacca agcgtgttat
      601 aatgaatact gctcaagcga ccttcaatcg tgaagcacac acgaccttca atcgtgaata
      661 aacgaataga tgggagactt accatgagtg ataactctaa aacacgtgtt gtcgtgggga
      721 tgagtggtgg tgttgattcg tcggtgacgg ctcttttgct caaggagcag ggctacgatg
      781 tgatcggtat cttcatgaag aactgggatg acacagatga aaacggcgtc tgtacggcga
      841 ccgaagatta caaggatgtg gttgcggtgg cagaccagat tggcattccc tactactctg
      901 tcaattttga aaaagagtac tgggaccgcg tttttgagta tttcctagcg gaataccgtg
      961 cagggcgcac gccaaatccg gacgttatgt gcaacaagga aatcaagttc aaggcctttt
     1021 tggactatgc catgaccttg ggggcagact atgtagcgac tgggcattat gctcgagtgg
     1081 cgcgtgatga ggacggcact gttcacatgc ttcgtggcgt ggacaatggc aaggaccaga
     1141 cctatttcct cagccaactt tcgcaagaac aacttcaaaa aaccatgttc ccactaggac
     1201 atttggaaaa gcctgaagtt cgaaaactag cagaagaagc aggcctttcg actgctaaga
     1261 agaaagactc gacagggatt tgctttatcg gagaaaagaa ctttaaaaac ttcctcagca
     1321 actacctgcc agctcagcct ggtcgcatga tgactgtgga tggtcgcgat atgggcgagc
     1381 atgcaggtct gatgtattat acaatcggtc agcgtggcgg actcggtatc ggtgggcaac
     1441 acggcggtga caatgcccct tggttcgttg tcggaaaaga tctaagcaag aatattctct
     1501 atgtaggaca aggattctac catgattcgc tcatgtcaac tagcctagaa gccagtcaag
     1561 tccactttac tcgtgaaatg ccagaagagt ttacgctaga atgtacggct aaattccgtt
     1621 accgtcagcc tgactctaag gtgaccgtcc atgtcaaagg agacaaggca gaggtcatct
     1681 ttgcggaacc acaacgcgcg attacaccag gccaggcagt tgtcttttac gatggcgaag
     1741 agtgtctagg tggtggtttg attgacaatg cttaccgcga tggacaagtt tgtcagtaca
     1801 tttagattga caaattttct caatttgcta caataataac agcaatagaa atgatggtca
     1861 aagctcatgg atgttgcagg cttttttgtc ctgcacttct ttggagtttt gactgttttt
     1921 gtgtcgttta agggaaagga caagaatgac tcaacaagac tttcggacaa aagtagacaa
     1981 tacggttttt ggtgttcggg cgacagcttt gattcttcaa aatcacaagc ttctagtcac
     2041 caaagacaag ggcaagtatt acactatcgg cggtgcgatt caagtcaatg aaagcacgga
     2101 agacgcggta gtccgtgaag tgaaggaaga actgggtgtc aaagctcaag ctgggcagct
     2161 agcttttgtg gttgaaaatc gttttgaaca ggacggtgtt tcctatcaca atatcgagtt
     2221 tcattatctg gtggacttac ttgaggatgc cccattgacc atgcaggaag atgagaaaag
     2281 gcagccctgt gagtggattg acttggataa gcttgaggat atccagctag ttccagcctt
     2341 tttaaaaacg gccctaccag attgggaagg ccaactaaga cacattcatc ttgaggaata
     2401 ggagagaaac atgacttatc attttactga agaatacgat attattgtaa ttggtgcggg
     2461 acacgctggg gttgaggctt ccttggccgc tagccgtatg ggctgtaagg tcctgcttgc
     2521 gaccatcaat attgaaatgc tggctttcat gccttgtaat ccctctatcg gtggttctgc
     2581 taaggggatt gtcgtacgtg aagtcgatgc cctcggcggc gagatggcca agaccattga
     2641 caagacttac atccagatga agatgctcaa cacagggaag ggcccagccg ttcgtgccct
     2701 tcgtgcgcag gctgataagg aactttactc taaggaaatg cgcaagacag ttgaaaatca
     2761 agaaaatctg acccttcgtc aaaccatgat tgatgagatt ttggtggaag atggcaaggt
     2821 tgtcggtgtg cgtacagcca cccatcaaga atatgctgct aaggctgtta ttgtgacgac
     2881 agggactgct ctccgtgggg aaattatcat cggagacctc aagtactcat caggtcctaa
     2941 ccacagcttg gcttctatta acctagctga caatctcaag gaactgggtc tcgaaatcgg
     3001 tcgtttcaag acaggaaccc ctccacgtgt caaggcttct tctatcaatt acgatgtgac
     3061 ggaaattcag ccaggagacg aagtgcctaa tcatttctca tacacttcac gtgatgagga
     3121 ttatgtcaaa gatcaagtgc catgctggtt gacctatacc aatggtacca gtcatgagat
     3181 tatccaaaac aacctccacc gtgcgcctat gtttacaggt gtggtcaagg gagtggggcc
     3241 tcgttactgt ccgtcgattg aagacaagat tgtgcgcttt gcggacaagg aacgtcacca
     3301 actctttctt gagccagaag ggcgcaatac tgaggaagtc tatgttcaag gactttcaac
     3361 cagtctgcct gaggatgtcc agcgtgactt ggttcattcc atcaaaggtt tggaaaatgc
     3421 agagatgatg cggacaggtt atgctattga gtatgatatg gtcttgcctc atcagttgcg
     3481 tgcgactttg gaaaccaaga aaatctcagg tctcttcact gctggtcaga caaatggaac
     3541 atcaggttat gaagaagctg ctggccaagg gattatcgcg ggtatcaatg cggctctgaa
     3601 aatccaaggt aaacctgagt tgattctaaa acgaagtgac ggttatatcg gggtgatgat
     3661 cgacgacttg gtgaccaagg gaaccattga accttaccgt ctcttgacca gtcgtgctga
     3721 ataccgtctc attcttcgtc atgacaatgc tgatatgcgc ttgactgaga tgggacgcga
     3781 gattggcctt gtggatgatg aacgctgggc tcgttttgaa atcaagaaaa atcaatttga
     3841 taatgagatg aaacgcctag acagtatcaa actcaagcca gtcaaggaaa ccaatgctaa
     3901 ggttgaggaa atgggcttca agccgttgac agatgcggtg acagccaaag aattccttcg
     3961 ccgtccagaa gtttcttacc aagatgtggt ggccttcatc ggaccagctg cagaagactt
     4021 ggatgacaag attatcgaat tgattgaaac agaaatcaag tacgaaggct atatttcaaa
     4081 agccatggat caggttgcca agatgaaacg tatggaagaa aaacgcattc cagccaatat
     4141 tgactgggat gacatcgatt ctattgcgac ggaagctcgt cagaagttca aactcatcaa
     4201 tccagaaacc atcggccaag ccagccgtat ttcgggagta aacccagcag atatttctat
     4261 tttgatggtg tatctggaag gtaaaaatcg tagtatttct aaaactcttc aaaaatcaaa
     4321 atgatacgtc gtcggcttct tacgaatgag ttcaaagctt ggctttgatt catctccagc
     4381 ctcccatagt tccccgaact atgggagcta actcaagtta tgcattttcc tagccttctg
     4441 gtctgatttt cattgagttt taatctcaaa agaaagcata gagaaaaaca gctccgaaga
     4501 cggagctgtt ttgttgactt gtactcaatg a
//
LOCUS       DAVBNN010000090         4348 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBNN010000090 DAVBNN010000000
VERSION     DAVBNN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.090"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(14..661)
                     /locus_tag="VQ847_001971"
     CDS             complement(14..661)
                     /locus_tag="VQ847_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3051254.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(770..1288)
                     /locus_tag="VQ847_001972"
     CDS             complement(770..1288)
                     /locus_tag="VQ847_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3051255.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1515..2384)
                     /gene="rsmI"
                     /locus_tag="VQ847_001973"
     CDS             complement(1515..2384)
                     /gene="rsmI"
                     /locus_tag="VQ847_001973"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3051256.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2387..2704)
                     /gene="yabA"
                     /locus_tag="VQ847_001974"
     CDS             complement(2387..2704)
                     /gene="yabA"
                     /locus_tag="VQ847_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3051257.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2744..3634)
                     /locus_tag="VQ847_001975"
     CDS             complement(2744..3634)
                     /locus_tag="VQ847_001975"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3051258.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3631..4269)
                     /locus_tag="VQ847_001976"
     CDS             complement(3631..4269)
                     /locus_tag="VQ847_001976"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3051259.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
BASE COUNT         1199 a          991 c          702 g         1456 t
ORIGIN      
        1 tatcaatcat gaactaggat tctagttttg caggaagtct aatgtaattc tcaagctgtg
       61 agttcattat gatttgtaaa tccgatatat cttcagcagc taaaaacaca ttttgaaatg
      121 ttccaagtcc gttttcacca aaactatatt ctctcttact atacttactc ttattattct
      181 ctatatagtt agagtcaagg ttcttaacct cttgaagttc attttcttta cttctgaggt
      241 taaaatcttt tacttctgaa gttaagtttt ttgacttctg taagtcattt tcttttacct
      301 gaaatatact cataaagtct ttaacataaa tgatgttcgg cttaccaagt ccaagcctta
      361 ctctttcgat cagtcctatt ccttttttta catcaagctc atctaatgtt tttatggcag
      421 ttggctttga gatatttctt cttttcataa tttcttcgac agtaaaatag ataaatactc
      481 tgccttcctt gtctatccag ttattcttaa atgacattcc tgtctgttta agaagtatgg
      541 aataaaggat aattgcttct gctgataagc cccgaaattc ttctctatca actaatatct
      601 ccggtacttt taagaagtta aatctttccg cttctctgtt ataaaaatat tcaaagtcca
      661 tgcaagatca cctcccttct taaaaatttg caaagaaaaa gacgatagtt tttcttctat
      721 cgcctttggt aaccattttt atgaaatttt ttaaagttaa aaatataatt tataatacta
      781 tcttcttcca ttttctgatt ttagttctga aagttccaaa aggtgcaacc gtatttacat
      841 gaataaactt atacacttcc caagtcgctg ttttagtcgc ttcatcagcc cactttctca
      901 tatgcggttc aaataattct tcctcactca acgaatcaat cattgcagag atagaattaa
      961 tattttcatt taattttgct ttcaactctt gcagagataa atgagcgtag gtatctgtga
     1021 accactgata taattcacca agttgattcc atttaaattt atccgatggt gtttttactt
     1081 gaagcccctt tctttcatct tcttcccatt taagaaccaa gttggtccaa ccaacctgat
     1141 aagcaaggtt ttctgctgga gttctgtcaa cttcatcagc tctcttatct tttaaatttt
     1201 ctggaatatt atcaaattct aaaatatatt tctcaaatgt tttctctatc tcagctttta
     1261 gttcttcttt attttcgtat gttcgcaaaa aatcaccttc tttctgattt atcaatcctt
     1321 tgatttaaaa tgaccttatt tttctattta taccttctaa gaacgctata actgctgctc
     1381 caaccatcgg tattccgtat gggcttaata aaaaacttaa taccaaagct tctataccaa
     1441 gtgatacatc tttatattac catcactaat taagttaaac agaaacagac agaattatta
     1501 cattctgtct ccctttattg tttttcttcc caatcgtggt aggcagcgta gagttgactc
     1561 ttattccact ggtaaatctt agctacttcc ttaatagctt gatttttctt catgccttgc
     1621 tggatacggg cttggatttc taagaacaag tcctcctcgt ctttttcctc cacatcctga
     1681 ctggcacctt caacaataag aaggcattcg cccttgagtg gcgtttcagc gatgctttcc
     1741 agcaattcag aaatggtacc tctttggtat tcttcataga ttttagtcaa ttccctgacc
     1801 aagactaccg agcggtcacc gtagacttct agcatatttt ccaatgtatc tgccacacga
     1861 tgggacgatt cataaaaaat ctgagtttca ggatagtctt ttttcgagtc gaaaaattgc
     1921 ttttgctgac ctgattttct cggtaaaaag ccgtaaaaga tatgtggctg cggcgctaaa
     1981 ccactggcaa tcaaggcaga aattcctgca gaggcacctg gaacagtcac aactgcaatt
     2041 tcttcctcaa tagctgcctt aaccaaatca tgaccagggt ctgaaatgct aggcaaaccg
     2101 gcatcagaga cctgagcaat actttgccct gctttcaaga aaccaatcaa atcaggaatt
     2161 ttttccttgg cattgtgctc atgaaaactg atctgcttgg tggaaatgtc aaaatgcttg
     2221 agcaaaagac ctgtattgcg cgtatcctca gcagcaatcc agtccacttc tttcaaggtc
     2281 tggatagcgc gaaaagtcat atcatctaga ttgccaatcg gcgttgccac tagatacagc
     2341 ttgccatagg gagactgccc cttaaaactt ttttgaattt gcatgcctac tccctgtata
     2401 acaactcatc acagaacata cattcttcgt cctgctctcg acgttgtcca taaaaatcat
     2461 tacatacgtg aaatccatca cggtaaatac gacggacact ttcgcgaaca tgcttggcct
     2521 tgacgggagc gtctgcttcc acctcaccca agcgttctcg caacttacta ttttccaagc
     2581 gaagagctgt attttcctct accaggctct tgagattttt cttgatggct tccacatcgg
     2641 ccaaggttac caataattgt tgggaaaaat catccagcgc gtcaaataat tcttttttgt
     2701 ccataaaaca gctctttcct ttctttatca ttcatttttg agtttatatt tctttcaaga
     2761 ccagatattc catggcattt tgaaagctga cattagcttg ccacattttt ctagcttcta
     2821 gtaaatcttg tagaatcact cttactctta cctgcaagag gtcctgccca cagagaactt
     2881 caagaatccg taaaacctga tcctgttttt ccttatcatc tgccaagttg gctaatttgg
     2941 caacctgtag ataactttct tttttcttag ctactaacca agtcagcagg cgttcacttt
     3001 catcgaccaa ggtccaaaaa cttgcctgat tagccaactt ttctgcttca gctcgcgatt
     3061 gactaaactt agctaaaaga gtcgcttttt tcttaacaag tcccatttgt tctaagagta
     3121 agataagttt ttcttcttgc tttttaaagt ggaagatctg ggtccgactt cggattgtcg
     3181 gtaacatctt ttcctcatcg ctagtcaaga agaaaatata aacttcactc tggggttctt
     3241 cgatgacctt gagcagagaa ttggctgcgt tgggatgcat tttatccgct tgctcgatga
     3301 taaagacctg ttgctggctt tcaatccctg cttgagaaaa ctgtcccacc aattccctaa
     3361 tgcgttctgt cttgatgacc tgattgactg gcttaatcaa ggtgacatcg ggaaattctc
     3421 cctgttcaat cagcttgcaa cttcggcatt tctcacatgg taagacgcca actttatccg
     3481 tacaaaagag gctcttagct aaaaattgcg ctatttccaa gcttccaaag aaacctgaaa
     3541 agagataggc gtgattgagc tggtcttgtt ctaagatacg gacaaaacgg tcaaactgag
     3601 ctggttgcca agcctttagt tgatcttgtt tcatttggcc aagcccattc cgtcaaacaa
     3661 gacagccttg gtagtttcca caacttgctc caaagggaga ctagcatcaa tcttgacaat
     3721 gcgatttccc tctttatcca gaagagaaag gtagccttga cgaacttttt tatgcaagtc
     3781 caacccttcc aaatccaaac gattaacctc gcggtcacta ttagcagcaa tacgagccag
     3841 cccttcttcc acctcgatgt caaaatagag tgtcaaatcg ggtttgaggc catctgtcgc
     3901 aaactgattg agccagtcaa tggcttcaat atctaagcca cgaccaaatc cctgataggc
     3961 aacagaacta tcgataaaac gatccatgat gaccaacttg ccagcttcaa gggctggaag
     4021 aactttttcc accaaatgct gtctgcgact ggcaatatag agaagtagct ctgttttagc
     4081 atccatctga gtatgacttg gatccaaaat cacttcccga atcttctccc caatcaagac
     4141 tccgccaggt tcacgggtcg tcagcacctt tactcctttt tcctctaaaa ttggtagcag
     4201 agcctctaaa acactggtct tgcctgctcc ctctggtccc tcaagagaga ctaaaaatcc
     4261 ttttgacatg tctaactcat ttctttttta ctacttctat tctatcaaaa aaataggggt
     4321 ttgtgacaat ctttttgtct tctcattt
//
LOCUS       DAVBNN010000091         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBNN010000091 DAVBNN010000000
VERSION     DAVBNN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.091"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ847_001977"
     CDS             complement(60..659)
                     /locus_tag="VQ847_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3051260.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ847_001978"
     CDS             complement(661..1758)
                     /locus_tag="VQ847_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3051261.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ847_001979"
     CDS             complement(1758..2495)
                     /locus_tag="VQ847_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3051262.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ847_001980"
     CDS             complement(2497..3381)
                     /locus_tag="VQ847_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3051263.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ847_001981"
     CDS             complement(3368..3562)
                     /locus_tag="VQ847_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051264.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ847_001982"
     CDS             complement(3559..3765)
                     /locus_tag="VQ847_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051265.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          963 c          701 g         1262 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctccttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBNN010000092         4302 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBNN010000092 DAVBNN010000000
VERSION     DAVBNN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4302
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.092"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(1..200)
                     /locus_tag="VQ847_001983"
                     /pseudo
     CDS             complement(1..200)
                     /locus_tag="VQ847_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(276..710)
                     /locus_tag="VQ847_001984"
     CDS             complement(276..710)
                     /locus_tag="VQ847_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3051266.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(786..1636)
                     /gene="rfbD"
                     /locus_tag="VQ847_001985"
                     /pseudo
     CDS             complement(786..1636)
                     /gene="rfbD"
                     /locus_tag="VQ847_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1702..2751)
                     /gene="rfbB"
                     /locus_tag="VQ847_001986"
     CDS             complement(1702..2751)
                     /gene="rfbB"
                     /locus_tag="VQ847_001986"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3051267.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2761..3357)
                     /locus_tag="VQ847_001987"
     CDS             complement(2761..3357)
                     /locus_tag="VQ847_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3051268.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3358..4215)
                     /gene="rfbA"
                     /locus_tag="VQ847_001988"
     CDS             complement(3358..4215)
                     /gene="rfbA"
                     /locus_tag="VQ847_001988"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3051269.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1202 a         1007 c          780 g         1313 t
ORIGIN      
        1 cgttcatcag ctggcaaagc ctcccagtct ctttccaagg aaaataactg atcacaataa
       61 gctaaacctt tagctcctaa ggatgattta tccgtttgct tggggggcgc ttcaaaaaac
      121 ttccttctca catgtgccca acatccaaca agttcagctt cttccagttg acgataagct
      181 tctagcggtt cgcagtttac caagcttagc gtcgccttgc tcctaaacct tggactgcta
      241 tcgcataggc agaactagag gactaaagtc ctaagttact gccgcaacat atcacaatgc
      301 acatagccag aataatctcc taggaattct tgtactacta aaccactccg acgctgatca
      361 tggtggtaca gcgtgattgc ttgattctca gctttcccag acaaaaaagt ccaatagtag
      421 gtcagatggc tatcactctc tagaacccga taagaggttt catccgcatg aagaagaggt
      481 tgttctaaca acttttctcg taaaaggtta taaagggact ctaaatagta ttgacttgcc
      541 ttgatatgcc aattagagat ttccttacgt gtgattggta aacccatcct agcccaatct
      601 tcttcttggc gataattggg taccttcaga ttaaacttct gatggatggt gtgagcgata
      661 atagaaactg agccaaagct atgcaccaaa gagaccagca ccaacaacaa gataattgta
      721 catcttaagc tcctttggag ttcattatct gcctctttta ttagactaga aaatcattct
      781 actacttatc tcacttcttg tttgtaaaat tcttgcaatg catcttgcca agttggaata
      841 acaaatccag tagctttggc tttggccagg ctcatcgttg agtttagcgg acgttgagct
      901 ttggctggaa attgactgga tctactggct tgacttcgac atctgtatct ttcaaaattt
      961 caactgcaaa atcataccat gttgtgtctt ctgtcgcatc atttgacaaa tgataataac
     1021 caaattcctt acgattttca gctaggtaga tcatgaattc agccaaggta cgagtccaag
     1081 tcggacgacc gtactggtca tttacaactg ttaaagtctt atgagttttc gcaagatttt
     1141 gcatggtaaa aacgaagttt ttgccataat ttccaaatac ccaggcagta cggataatat
     1201 agaaattaga cacatgcttc tcaactaact cttcccccat acgcttagtg cgtccatatt
     1261 ctgtctgtgg atctggtcgg tcatcaactt cccactcttg tccaactggt ttcttaccgt
     1321 caaagaccta gtccgtagaa atataaacta gagttgcacc atgcttttca gatgcttttg
     1381 cgacattttt tgtccccatc acattgatgg cgaagtccaa ctcttttcct tcatcctctg
     1441 ctgcatcaac agcggtgtag gctgcacaat ggtagactaa agtcggtttc acctcttcaa
     1501 aaactttctc aaccatttct tcattggtaa tgtccatctc agccacatct actgccacgt
     1561 attcttcatt acgttcatcc aataaatagc gaagttccgt tcctaattgg ccatttgccc
     1621 ctgtaattaa aatcatctct agacctttct aatatgtaac tcttcccaat atagcaataa
     1681 aaagcagcga tttcctgctt tttatactgt aataatctcc tgagtcttag cataattggc
     1741 ttcaacagct tctttttctg ctttccacca ttcttggtta tctgtatacc acttgattgt
     1801 tgccttgagc ccagcttcaa agttggtaaa ttcaggtttc caccccaact catcacggag
     1861 cttgctggca tcaatcgcat agcgaaggtc atgtcctgca cggtcagtca catgatcata
     1921 ggcatccgta gcttgtccca tttccttaag gataagttcc aaaacttcct tattgttctt
     1981 ctcaccatca gccccaatca agtaggtttc accgatttgc ccttttgtca agattgtcca
     2041 aactcctgaa gaatggtcat tggtatgaat ccagtcacga acgttcttac cttcaccgta
     2101 aagttttggc ttaattccac ttaggatgtt agtaatctga cgtgggatga atttttcgat
     2161 atgttgataa ggaccgtagt tatttgaaca gttggaaatc gttgccttga ctccaaaaga
     2221 acgcacccag gctttgacaa tcaagtctga tgcggccttg gttgatgagt acggagagct
     2281 tgggttgtat tttgtttcag cagtaaattt ctcacctggt ccttcaccat gacctggcaa
     2341 atcttctcgt aaagggagat ccccataaac ttcatctgtc gatacatggt ggaagcgaat
     2401 atcatactta cgagcagctt ctaaaagagt atagattcca atgaagttag tatgaataaa
     2461 tggcgatgga tcattgagcg aattatcatt gtggctttcc gctgcataat gaacgatagc
     2521 atctgcttga gcaaccaact tgtctaccaa ctccgcatca gcaatgtcac caacaactaa
     2581 ctcaacacga ttgcctaaaa tttcctcaat attcgcgcgg tttccagcat aagtcaactt
     2641 atctaggact gtcacgtgaa catctggaaa gttctcgtaa acataatgga caaagttaga
     2701 accgataaag ccagctccac ctgtcacgat aatatttttg tattcagtca tattctttcc
     2761 ttattccaaa tcttcttttt tcaaaggctt cacgtcctta agtaggggat gatgtttgtc
     2821 tgcttcagat acgtctgctt cttccagatt ttcccattca ataccaaggc ttggatcagc
     2881 gtagttcaca aaggcatact tgggtttgag ttcaagagcc cagtaatcat tgaccagata
     2941 gctatatgac actgtatctg ataaaacttg gaagccatta gctacgcctc gaggaacaaa
     3001 gattcccttg cttgcatcaa ttactgtctg ataggtattc ccaaaggttt caccctcgcg
     3061 tagatcaacc caagaaccca gaactttccc tccatctgct acagagatgt acttatccca
     3121 aggctctgcg tggaggcctc gaaggacatt tttacgtgag aaggatacat tgttttgcaa
     3181 ttttccttct gcaaagaaag actctggaaa tccaagtgga agcacttttt ccttttggaa
     3241 attttcttta aaccagccac gattatctcc atgaacgggg atatcaaact ccaacatgcc
     3301 tggaatagct tcaaccttgc gtgccgcaag cgtcttaccg aaaaaattat ctgtcatcta
     3361 tgcttctcca atcaaacgga gcagatactg tccgtattca tttttcttaa gtggttgggc
     3421 taaggccaat acatcttctc gactgatata gcccatacgg taagcaattt cttctaagtt
     3481 tgctacctga acattttgca tccgttgcac tgtttcgatg tactgtgaag cctctagtaa
     3541 actttcatga gttccagtat tcagccaagc aaagccacgt cccataagct caacagacaa
     3601 atcaccacga tctaggtaaa ccttgtttac atctgtaatt tccagttcac cacgagggct
     3661 tggtttaata ctcttggcaa tttcgacaac atcgttatca tagaaataca gtcctgtcac
     3721 tgcatagttg gagcgaggat actccggttt ttcttctatg gaaatagcat tcatgtctgt
     3781 atcaaactca accacaccaa aacgctctgg atccttcact tggtagccaa aaacagtcgc
     3841 acctttctct ttcttggctg ctttttgaag cattgtgctc agaccaggac catggtagat
     3901 attgtcgcct aaaatcaagg caacgctatc gtcagaaata aactcttccc caattgccaa
     3961 accatctgta cttggttgct ctgcataaga aagtttgatc ccaaactcag atccgtcttg
     4021 aagaagctct tgaaatcgat gtaaatcctg tggagtggaa ataatcaaaa tatccctaat
     4081 cccagccaac atcaatgttg aaagtgggta gtaaatcatc ggtttatcat aaaccggcat
     4141 aagttgtttt gacgcagcgc gagtcaaagg atataaacgt gtccccgaac cacctgctag
     4201 aataatacct ttcatagtag ggtacctttc tttgttattt tagagtcaat tactattaat
     4261 tgtgtactgc tctaaaaaga aaacaatcat cccatgtttt at
//
LOCUS       DAVBNN010000093         4287 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBNN010000093 DAVBNN010000000
VERSION     DAVBNN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.093"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            1..142
                     /locus_tag="VQ847_001989"
                     /pseudo
     CDS             1..142
                     /locus_tag="VQ847_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(135..308)
                     /locus_tag="VQ847_001990"
     CDS             complement(135..308)
                     /locus_tag="VQ847_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3051270.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(467..2074)
                     /locus_tag="VQ847_001991"
     CDS             complement(467..2074)
                     /locus_tag="VQ847_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3051271.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2227..3711
                     /locus_tag="VQ847_001992"
     CDS             2227..3711
                     /locus_tag="VQ847_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3051272.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3806..>4287
                     /locus_tag="VQ847_001993"
     CDS             3806..>4287
                     /locus_tag="VQ847_001993"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3051273.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1240 a          980 c          816 g         1251 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcataaa aggtattacc aagttgcaat accttttatg aggctctttt
      121 gtcttgttct tgtttcaatt gactatatta tcagtgtaat agtctaatag atagttaaat
      181 gtagttggat ttccactaaa ggttgatgag taagtttttg tatctgaacc tgattggccg
      241 caagcagcta aaagcaaaac agatgcaaaa gtcaggcctg cactaaggac acgcttcttt
      301 atgttcatct tctttctcct taatagtggg aatttgtaaa gttaattgaa tttcgagaat
      361 gaaagtttat aaaccttggt tataaaaaac aaaggatttc tgctttttat acagtcctcc
      421 cttgttttta tatgatttca attttaaatt tttctgcaaa aaatatttat agtaattcca
      481 cacagaaagc atcccatgga actaagattt gtttttcaaa gacttcttga gctagggtgt
      541 tttcaatcaa gacagatttg acttttcctt ctactgtcaa gtcttgctct tcattggaca
      601 agttagccac aactaggaag cgacggtcgc catccttacg tatataagca aagaccttat
      661 cagccgtatc aagcaattca aagtcagctc gaactagcca gctattctcc ttgcgaattt
      721 ggaccagttt ctgataggta tagaaaatag aatctggatt tgccagcgct tcttggacat
      781 tgatcatctc gtaatttgga ttaaccgcca accaaggttg acctgttgag aaaccagcgt
      841 ttttgctctc gtcccattgc ataggggtac gggcattgtc acgtccaata acacggatac
      901 tgtccatgat ttcttcaatc ggaacacctt tttcaagagc ctcacgcgca tagttgagag
      961 attcaatatc ttctacttga tccagcgttt caaagggata gttggtcatg ccaatttcct
     1021 caccttggta gatataagga gttcctctca tgagatgaag caagatggca aaggctttgg
     1081 cagatttttc gcggtattct tggtcatttc cccagattga gacaatacga gggaggtcat
     1141 ggttgttcca gaagagggaa ttccagccgt cctcaactcc taactctgtc tgccatttgt
     1201 tgaagatttc ttttaactta gcgatattca gctctttttg atagtgccat ttaggctgac
     1261 cttcctgata ctgaagaccg atatgttcaa actggaagac catagacaat tcttgcccct
     1321 ttggatcaga gtagagcttg gcaatctctg gcgttgctcc ccaagtctcc cctactgtca
     1381 agagatcctt atctccaaag gtcgcctgat tcatttcctt gagataggga tggagcatag
     1441 gaccattatt gactaccttc tcgtcaggaa ttttgccaat catgtcaata acatccatac
     1501 ggaaaccacc aataccctta tcaatccaga agttcatcat ctcataaatt ttctggcgaa
     1561 gtttttcatt ttcccagttg agatccggct gtttcttgct gaaaaagtgg agatagtatt
     1621 gacctgactt ttcatcgtat tcccaagcag acccactaaa gatagaatct aggtcattgg
     1681 gttcatcgcg ccagatatag tagtctcgct cagggctatt aggattttca caggcctcta
     1741 caaaccaggc atgctcatcc gaggtatgat tgaccaccaa gtccatgatg atacggatat
     1801 cacgcttctt agcttctgca atcagttgat ccatatcctc catggttcca aaaatcgttg
     1861 caatcgcttg ataatcagca atatcgtagc cattatcatc catagggctg tcataaacgg
     1921 gagaaagcca aattgctgtg attcctagct tggctagata gtccaactta ctggtaattc
     1981 ctggcaaatc gccaattcca tctccattac tatccataaa actctttgga tagacttgat
     2041 agactacggc attgtgccac catttttctt gcatcttctt acctcattat tttcataatc
     2101 tatagtctat gatagcactt tttaaaattt tgtgcaagcg tttgcttaat ctttttaatt
     2161 tcttttttag ctccgtagtt tcctaacttc caatttttta ttataataga gtccagaggt
     2221 aaaaaaatga aaaaacaagc ttttagttct gaacaatatt tgaatttaca acgcgaccat
     2281 attttggagc gcattaacca atttgacggc aagctctact tagagtttgg cggtaaaatg
     2341 ttagaagatt tccacgctgc tcgtgtcctt cctggttatg aacctgacaa caaaatcaag
     2401 ctcttgcaag aattgaaaga gcaggttgag gttgtgattg ccattaatgc tagcaacatt
     2461 gaacattcca aagcacgtgg cgacttaggc atttcttatg accaagaagt tcttcgtttg
     2521 attgacaaat tcaatgaatt agggattttt gttggttccg ttgtcattac acaatacgct
     2581 ggccaacccg ctgcagatgc cttccgcaat caacttgaga aaaacggaat tgattcttat
     2641 cttcattatc caatcaaagg atatccgacg gatatggatc acatcatttc cccagaaggc
     2701 atgggcaaaa acgactacat caaaaccagt cgcaacttga ttgtcgtaac cgctcctgga
     2761 cccggttctg gaaaattggc aacgtgtatg tccaatatgt accacgacca aatcaatggc
     2821 atcaagtctg gctacgctaa atttgaaacc ttccctgttt ggaatcttcc ccttcatcac
     2881 ccagttaact tggcttatga agctgccaca gctgaccttg atgatgtcaa catgattgac
     2941 cccttccatc ttcaaaccta tggagaaacc actgtcaact acaaccgtga tatcgaaatc
     3001 ttcccagtgc tcaagcgcat gttggaacgt attctcggaa aatcaccata cgcttcaccg
     3061 acagatatgg gtgtcaacat ggttggtttc gctattacag atgacgaggc tgctgtcgaa
     3121 gcttctaaac aagaaatcat ccgccgttac tatcaaacag ttcttgactt caaagctgaa
     3181 aaagttggcg aagctgccgt caagaaaatt gagttactca tgaacgacct cggtatcaca
     3241 cctgcagacc gtaaggttgc tgtcgttgcg cgccaaaaag cagaagaaac tggtggacca
     3301 gccctagcct ttgaattgcc aaatggggaa atcatcactg gtaagaactc agaactcttt
     3361 ggccctacag ccgctgcctt gatcaatgcc atcaaaaaat cagctgacat cgctaaagaa
     3421 gtaaaactaa tcgagcctga agttgttaag ccaatccaag gtcttaaaat cgatcatctc
     3481 ggtagccgca atccacgcct tcattcaaat gaaatcctga ttgcacttgc tatcacagct
     3541 acagaaaatc ctgatgctgc ccgcgctatg gaagaactcg gcaacctcaa aggaagcgaa
     3601 gcccactcaa ccatcatctt gactgatgaa gacaagaatg tccttcgtaa actgggtatc
     3661 aacgtaacct ttgacccata ctaccaatac gaccgcttat atcgtaagta aagatttcaa
     3721 cctctccagc ctcggagagg ttttctctct gtctcaggag caacctttat gatataatga
     3781 gagaagaaaa ctgaaaggat ttaccatgtc aaaagaagtt attgtcgaaa gttttgaact
     3841 tgaccacacc attgtcaaag caccctatgt tcgcttgatt ggggaagaaa caggaccaaa
     3901 aggagacatc atctccaatt atgatattcg cttggtgcaa ccaaacgaag actctatccc
     3961 tactgccggc cttcacacta tcgagcacct cttagccaaa ctcatccgta cccgcattga
     4021 cggcatgatt gactgttcac catttggttg ccgcacaggc ttccacatga ttatgtgggg
     4081 acgtcacacc agtgctaaaa tcgcagctgt tatcaaggat tcgctcaagg aaatcgctga
     4141 aactactact tgggaagatg tcccagggac aaccatcgaa tcttgcggaa actacaagga
     4201 ccacagcctc ttctctgcta aagaatgggc aaaactcatc ttggaacaag ggatttcaga
     4261 tgatgccttt gaacgtcatg tgattta
//
LOCUS       DAVBNN010000094         4193 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBNN010000094 DAVBNN010000000
VERSION     DAVBNN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.094"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            720..1712
                     /locus_tag="VQ847_001994"
     CDS             720..1712
                     /locus_tag="VQ847_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3051274.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VQ847_001995"
     CDS             1714..2532
                     /locus_tag="VQ847_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3051275.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VQ847_001996"
     CDS             2534..3319
                     /locus_tag="VQ847_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3051276.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VQ847_001997"
     CDS             3358..3636
                     /locus_tag="VQ847_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3051277.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VQ847_001998"
     CDS             3621..3818
                     /locus_tag="VQ847_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3051278.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1171 a          717 c          904 g         1401 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gagtgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aattttacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccagaaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaataa agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtagcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttatttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg act
//
LOCUS       DAVBNN010000095         3976 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBNN010000095 DAVBNN010000000
VERSION     DAVBNN010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3976
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.095"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(382..915)
                     /locus_tag="VQ847_001999"
     CDS             complement(382..915)
                     /locus_tag="VQ847_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3051279.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1004..1780)
                     /gene="recX"
                     /locus_tag="VQ847_002000"
     CDS             complement(1004..1780)
                     /gene="recX"
                     /locus_tag="VQ847_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3051280.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(1790..2566)
                     /locus_tag="VQ847_002001"
     CDS             complement(1790..2566)
                     /locus_tag="VQ847_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3051281.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2623..>3976
                     /gene="rlmD"
                     /locus_tag="VQ847_002002"
     CDS             2623..>3976
                     /gene="rlmD"
                     /locus_tag="VQ847_002002"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3051282.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1260 a          698 c          743 g         1275 t
ORIGIN      
        1 atttcatttt actatactat tacgaaatta gatatataaa tgaaaacttg cctcaaggta
       61 ggtttttttg ctagtagaaa agcgatagac agaaattgtt ggactcttaa aaaaatgaag
      121 ttttgctcaa aagagcttct taaattaaaa cgagcaatta tcagttcaaa tctgtttcaa
      181 aagaagaacg gataaattaa tcgatgcttt gtttttgagt taggaagtta agcatgccaa
      241 actgagtcgt aggaataaat ctctttctag taatgtgttg taactctgct ataatggatt
      301 tattcctttt tgtgtttaca caatttattt tatactacca aaaaaacaag gtcaggattt
      361 tgttcctgac ctttgacaac tttaccgatt ctttagttct acatagcgct tgtaccaaat
      421 gtttacatag gcttctgaga aaggaccacg tccattgtta atccaatcaa caagaatttt
      481 gacatgttct tttaaaatat agtccaagtc atcagaataa ttcattttgc gtttgtgacg
      541 ctcgtactct tcaacgtcca agagacgttt ttccccatct gtaaaaattt taacatccaa
      601 atcgtaatca atatacttca gtgcttcttc atccagatag taggggctag ccatattgca
      661 atagtaagaa gttccattat cacgaatcat ggcaatgata ttaaaccaat atttcttgtg
      721 aaagtaaaca atagccggtt ctcgagtgac ccaacgacga ccatcacttt cggtaacaag
      781 tgtatgatcg ttgacaccaa taatggcgtt ttctgttgtt tttagtacca tggtgtcccg
      841 ccaagttcgg tggagactcc catcatgctt ataactttga attgtaataa agtcgccttc
      901 ttttggaagc ttcataacta accaactttc tacaatttat aagtttatca tttactattg
      961 taccataaaa ttacctaaaa tctgtgaatt tcacttggaa atattaaaga tattctctaa
     1021 gagcgcttgc tatatccgaa aaatcgtagc cctttcgtgc taaaacttga gttaaacgct
     1081 gcttcagttc gtatccttca tactttcgag catacttact atattgttta tcaagttcct
     1141 tgaagatgag ttcttgagtc gtttcttggt caacttggct atctaagtcg tcaaaggcaa
     1201 ttttagcatc agaataagag aagcccttgt tagtcaagtt ctggataatc ttatcttgca
     1261 gggcacgaga tggaagtttt ccctcatatt ttttcaatag tttattagct acacgttgag
     1321 caacttcaga aaaatcaaat tctttcaagt tctcttctat agtagatttt gaaatccctt
     1381 tttgagctag tttctgagtc agcacataag gacccttgtc tcctgaaagt tgattggtat
     1441 tgatgatagc ataagcgtac tgaccatcat taatccactt atcttcttta agattagcaa
     1501 taacttgaga aacgatgttt ttatcaatat cgtatttttt cagatattct ctgacttctt
     1561 tttcagtgcg tgctttaaag gataagtggt agagagcgag attcttacca taagaaaact
     1621 gggcaaaatc ctgaatctcg gtcagttcct ctttactaat gaccttatct cgagacagca
     1681 taaaacggac aatggtatct tccgtgatat aagaggtttg ctgtccatct agttccatca
     1741 agtagagacg ttttttcttt tcaagttttg tgattttcat aatttccttt catctaaatg
     1801 cttcgaaagc tgcaacaagt cgtagtttat ccatatttac atattctcta ccgtaatagt
     1861 cgagaaataa ttcagcatac gtagcatctt gtaggttgta atgaagggac caaattgccc
     1921 aaaagaggtc gatatgtcgg tcactaaaac cagccaatcc caagtcaata aagcaagaaa
     1981 aatgagaggc atccttcaag atgaaatttg gcaggcaggc atctccatga ataaaagcat
     2041 cagctttgag aatgtaacct ttctcttgta tcagttggta agcttcttca cgactgtgaa
     2101 tgtgaaattg aggcagaaga gtcttgttat aaaaagtccc cttctgatag ttttttaagg
     2161 ctttttcttt ataacgcttc agatgatttt ccgacggaaa agattgtggt ttaagactgt
     2221 gaagtttgtt taatgcttga gccagggttt gacagagtct ttcgggttga tttaaaaaag
     2281 cgagagcgtt gctgccaatg gcttctttag tcagaaggaa gtccttattt gctgataaat
     2341 aggtaatcac tggagttccc aatccttcag tttcgaacca acttgcaatc ttagtttctt
     2401 gagctaatct gcctttttga tctattttta aatagtaacc tgaatctata tataggacag
     2461 ttgcacttga atgagaagaa ctatcagaga gattagctcc cttgatatag cttcgtaatt
     2521 gttcagggaa atctagtata ctaaagcgag gtgtttttga attcatgctt ttattgtaac
     2581 atattcttaa atatcttaga aactccatgg tataatagac atatgaatct gaaagtgaaa
     2641 caaaaaatac cattaaaaat caagcgcatg ggaattaacg gtgagggaat cggcttttac
     2701 caaaaaacat tagtctttgt accaggagct ctcaaaggcg aagatatcta ttgtcagatt
     2761 acttctatta gacgcaactt tgttgaagca aaattactga aggtcaacaa gaagtctaaa
     2821 tttcgaattg tgccatcttg tactatttat aatgaatgcg gaggctgcca aatcatgcac
     2881 ctgcattatg ataagcagct ggagttcaag acggacttac ttcatcaagc gctgaaaaaa
     2941 tttgctcctg caggatatga aaattatgaa attcgtccaa ctattggaat gcaggaacca
     3001 aaatattaca gagctaagtt acaatttcag actcgaaaat ttaaaaatca ggtcaaggcg
     3061 ggcttatatg cacaaaactc tcactattta gtagagttga aagactgcct ggtacaagat
     3121 aaggaaaccc aagtgattgc taatcgctta gcagaattac ttacttatca ccagattcca
     3181 atcacggatg agagaaaagt tctaggtgtc cgtactatta tggtccgacg cgcgagaaag
     3241 accggacagg ttcagattat tattgttaca aaccgccagc ttaatttaac tcaattggta
     3301 aaagagttgg ttaaagattt cccagaagtt gtgacagtag ctgttaatac aaatacagct
     3361 aaaaccagtg agatatatgg tgaaaagaca gagattatct gggggcaaga gagtattcaa
     3421 gaaggtgtac tcaattatga attttcacta tcccctcgag ctttttatca actaaatcct
     3481 gagcaaacag aagtcctcta tagcgaagca gtaaaagcgc tggatgttga taaagaaaac
     3541 catttgattg acgcttattg tggagttgga acgattggat ttgcctttgc aaagaaagta
     3601 aaaacactca gaggtatgga tattattcca gaagctattg aagatgccaa gcgaaatgct
     3661 aaaagaatgg gatttgacaa tactcattat gaagctggaa cggcagaaga gattattcct
     3721 cgttggtaca aggaaggcta ccgagcagat gctttgattg ttgacccacc acgtacaggt
     3781 ctggatgata agttattaga tactattctt acttatgtac cagaaaaaat ggtttatatt
     3841 tcttgtaatg tttcgacctt ggctcgtgat ttggtacgct tagtagaagt ctatgatctt
     3901 cattatatcc agtcggtcga tatgttccca catacagctc gaactgaagc tgttgtaaaa
     3961 ttaataaaaa aagttt
//
LOCUS       DAVBNN010000096         3392 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBNN010000096 DAVBNN010000000
VERSION     DAVBNN010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.096"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            320..1666
                     /gene="gdhA"
                     /locus_tag="VQ847_002003"
     CDS             320..1666
                     /gene="gdhA"
                     /locus_tag="VQ847_002003"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3051283.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2162..2332)
                     /locus_tag="VQ847_002004"
     CDS             complement(2162..2332)
                     /locus_tag="VQ847_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051284.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2345..2986)
                     /locus_tag="VQ847_002005"
     CDS             complement(2345..2986)
                     /locus_tag="VQ847_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3051285.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT         1071 a          641 c          562 g         1118 t
ORIGIN      
        1 cttttttatt ttagtctagt ctaaatattg cttttctcca aaatggtcat agttttactg
       61 gcaaatctaa catatcacgg ataaattaac aagtgatttc tgaattgcta aacattttct
      121 tttcttatag catactttaa gattttgtct ttgagaaaga tatttccaag aaaaacgttc
      181 gtttttttat ctattttcaa aaaaaccaaa aaactgaatt gaaagaattt ttagaaaatt
      241 tctgtttttt ctttacagtg aaaaaaaatt ctgctataat gtcttatgta ataaaatatg
      301 acaataaaag gagaacgata tgacatctgc taaagaatat atccaaagcg tgtttgaaac
      361 tgtgaaagct cgtaacgggc acgaggctga attcctccaa gctgttgaag aatttttcaa
      421 cactttagaa cctgtatttg aaaaacaccc tgagtatatc gaagaaaata tcttggcacg
      481 tattactgag cctgagcgcg tggtttcttt ccgtgttcct tgggttgacc gtgatggaaa
      541 aattcaagta aaccgtggtt accgtgttca attcaactca gctgttggac catacaaagg
      601 tggacttcgt ttccacccaa ctgtaaacca agggatcttg aaattcctcg gatttgaaca
      661 aatctttaaa aatgtcttga ctggacttcc tatcggtgga ggtaaaggtg gatcagactt
      721 cgatcctaaa ggtaaaacag atgctgaagt gatgcgcttc tgccaaagct tcatgactga
      781 attgcaaaaa cacatcggac catcacttga cgtacctgct ggtgatatcg gtgttggtgg
      841 acgtgaaatt ggttaccttt acggtcaata caaacgtctt aaccaatttg atgctggtgt
      901 cttgactggt aaacctcttg gatttggtgg tagcttgatt cgtccagaag caactggtta
      961 cggtttggtt tactatactg aagaaatgct caaagctaac ggtaacagct ttgctggtaa
     1021 gaaagtcgtt atttcaggtt ctggtaacgt tgctcaatat gctcttcaaa aagcaactga
     1081 actcggtgca actgttattt ctgtttctga ctcaaatggt tatgtcatcg atgaaaatgg
     1141 tatcgacttc gatcttttgg ttgatgttaa agaaaaacgt cgtgctcgtt tgactgagta
     1201 tgcagctgaa aaagcaactg caacctacca cgaaggtact gtatggactt acgctggaaa
     1261 ctatgacatt gctcttccat gtgccactca aaacgaaatc aacggtgaag cagctaaacg
     1321 tttggttgct caaggcatta tctgtgtatc tgaaggtgcc aacatgccga gcgaccttga
     1381 tgccatcaaa gtttacaaag aaaatggtat cttatacgga cctgcaaaag ctgccaacgc
     1441 tggtggtgta gccgtttcag ctcttgaaat gagccaaaac agtcttcgcc tctcatggac
     1501 tcgtgaagaa gttgatgacc gtctcaaaga catcatgaca aacatcttca acacagctaa
     1561 aacgacttca gaaacatacg gtcttgataa agactacctt gcaggagcta acattgctgc
     1621 ctttgaaaat gtagcaaacg ctatgattgc ccaaggtatt gtttaagatt tatttgctta
     1681 atcctcaatc actacgattg gggattttta gttgagttag acagttggga aattctaatt
     1741 aaatgaaata aaaactgaac aaattgattg cggaattcaa accaatttct aacatatttc
     1801 tagaaattaa tttgactttt ctaatcgatt tgttcatatc ttatttcaat ttactatact
     1861 tacttaaccc tttttatact caatgaaaat caaagagcaa actaggaagc gagtcgcagg
     1921 ctgtacttga gtacggcaag gcaaagctga cgtggtttga agagattttc aaagagtatt
     1981 aaacaaaaag aaaaaacgct actcctaaga atagcgattt aatcatgttt ttaagctact
     2041 actgtagttg ctctattatt taagtgttat gaataacttc aatatcttta aagctttttg
     2101 ttagatttat aatttcaact atagccatct ctactcctta gtttacagca aaaaattatg
     2161 cttaattctt attgtttttg taaacaatca gcgaacccaa tactattcca ttcaacaatc
     2221 ctaaagaaat accatattca actggaaaat ctaaaaaaat tgcaaacact attccaatca
     2281 tcacccctag tgaggctgtt gttaaaatta catattcatt ttctttcttc attttcttta
     2341 cacctcattt cctttttgta tataagctgt agtactctcc accaagatcc attaagtact
     2401 tatgatttcc tgactcaaca atcttaccac ctttcattac aacaataata tccgcatcct
     2461 taatcgttga caatctatga gctacaatta tttgagtaca gccctgactt tttatatact
     2521 ttgttattct ttcctcatta atagtgtcta aagcactagt tgcttcatct aaaattacaa
     2581 tactaggatt atttattaat gcacgtgcca gtgctatccg ttgtctttga ccacctgaaa
     2641 tatttgaacc catctctgag atgatagtat taaatttcat cggcatagcc atgatttcat
     2701 catagatttg aactgcttta caaacttcct ctatcttttg tgaagtaact tcgtgcttta
     2761 aagttatgtt atcaagaata cttctgttca ataaaaacga atcctgtgga actactccta
     2821 aattttgact taatattttt ttatctattt gattaatatt tacaccatca aataaaactt
     2881 ttcctgtatc aatcttatat aatcctgatg gtatttttga taatgtactt tttcctgacc
     2941 ccggttgacc gactagtgca attctctgtc ctgactcaat agtcaaattt aaattttcta
     3001 ttacaggagc tgagtctttg gaataagaga aagataggtc cttaatatct attctacttc
     3061 aaacgtttct aaactatact ccggaaaata atttaaccaa taactatctt tcatcgtatc
     3121 ctccaaccag tactaagagt ctgggacaat agtctcttat ctccaaaaaa gaagcggatt
     3181 tgccgttgct tttttgcatg gttgcgatag tcttggtaaa atagaattgc ccaataaacc
     3241 atttagaagg gctatcccat gcatattcac tataacacaa atcaaacaac tttaccacta
     3301 gaaatcagtt ctttcttgcc gcaagaccat ctcgtcttta ctattgaaaa agtggtgaat
     3361 accgatgaaa aggaggtaaa ccatctgatt aa
//
LOCUS       DAVBNN010000097         3258 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBNN010000097 DAVBNN010000000
VERSION     DAVBNN010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.097"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(182..793)
                     /gene="rpsD"
                     /locus_tag="VQ847_002006"
     CDS             complement(182..793)
                     /gene="rpsD"
                     /locus_tag="VQ847_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3051286.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(988..2040)
                     /locus_tag="VQ847_002007"
     CDS             complement(988..2040)
                     /locus_tag="VQ847_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3051287.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2037..2735)
                     /locus_tag="VQ847_002008"
     CDS             complement(2037..2735)
                     /locus_tag="VQ847_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3051288.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2902..>3258)
                     /locus_tag="VQ847_002009"
     CDS             complement(2902..>3258)
                     /locus_tag="VQ847_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3051289.1"
                     /translation="ATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTD
                     SMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGLLGLAL
                     AGLLGGLGLKNKKEEN"
BASE COUNT          908 a          736 c          622 g          992 t
ORIGIN      
        1 agattatacc acattgtgta ctatttttgg ttcattttac tatatcactt tggactatat
       61 cggtctagtt atgtctcaac gattatagct ggatactaag agaaatcaaa aaagcactaa
      121 gggagaacgt cccaaagtgc ttaatatcaa ggcctcaaag cctgtcttat tcaataaaat
      181 attacaacat cttgttgtag aattcaacga caagtgcttc gttgatttct gggttgattt
      241 cgtcgcgttc tggcaagcga gtcaatgaac cttccaactt ttcagcgtcg aatgatacga
      301 atgctggacg tccaagagta gcttctactg cttcaaggat tgctggaact ttcaatgatt
      361 tttcacgaac tgagatcact tgacctggag ttacgcggta tgatgggata tcaacgcgtt
      421 tcccgtcaac aaggatgtga ccgtggttta cgaattgacg agcttgacga cgagtagtcg
      481 cgagaccaag acggtaaaca acattatcca aacgacgttc caaaagaagc ataaagttga
      541 aacctaggat tccacctttg atttttgtag cttgtacgaa caagttacgg aattgttttt
      601 cacctacacc gtaagtgaaa cgaagttttt gtttttcagc caattgcaaa ccgtattctg
      661 acaatttaga acggttgttt ggtccgtgtt gtcctggtac gtagttacga cgtgccaatt
      721 ctttacctgt acctgtaagt gaaaggccaa ggcgacgagc ttgtttccaa gatggtcctg
      781 tataacgtga catatgaatg tcctcctgat ataaataata tttcggtgga aatagtcact
      841 tagaaagccc tgattcgtgc agatgccctt cgcctaaaca gccaaggtta cttatcataa
      901 gacacctgtt gacgagcttc atgctttcct gctgatattt cacacaaaat ccattctacc
      961 atgaatagct ggatttgtaa aggggtttta ggctttattt tcactaccag agaggttgag
     1021 aacgagggta aaggtacttc ctagaccgta ctggctgctg actgtgattt ccccacccaa
     1081 ttgatgggcc aattcacgcg caatcgcaag tcctaatcca tgaccacctg tcttcatgtt
     1141 acgcgaagtt tcgacacgat aaaggcgttt gaaaatattt tccaaatcct ctggggcaat
     1201 gccctgccct tcatcggtca cactgattga aagctggtcc ttctccagct tagccaccac
     1261 ttccagcttg gttcctggag cagaatattt aaaagcgtta tcgaccagat tcaccaagat
     1321 acgagaaagc ttagcataat ctccctcaat ccgggcagac tctgggatta cctgcaagtg
     1381 gacatctctt ctctcctgct caatcaaaaa ctgaaattca ctcatgcact caattaagag
     1441 cttgtccaga aaaatactgt ctttactggt agtttccacc tgatttctag ctgtgtttag
     1501 ggtcaaaaaa ttcaactcct caaccagttt attgagcctc tccgtctggc gtccaatggt
     1561 tgctagataa tgagcttgct ccgactcctt gataatccca tccaaaatcc cttctaccgt
     1621 cgcttggatc gaagtgatag gagtcttaat atcatgcgac aactgagcaa tcatcaagcc
     1681 cttttctcgt tcgctttctt ccaaggaatc aaagcttacc tgcaaatcat gggacatctc
     1741 attaaaagtt tgccctaatt gctgaaattc tacaggacct tgaacctcca aatttgaagg
     1801 aaaatccttg gccgctaccc gcttggcatg ctccttgagt ttgcccaacg acgtaaagac
     1861 tggcaatagg agaaagagac taatcccagc accgacaagg ctggcaacga tggtcatccc
     1921 aagcaaaaag taaatctcgc ctttcgcaat cagcattttt tgaacagccc aaaaaacaac
     1981 caaaatggtt aagagggttg aaataatata tccaaccaaa atataacttt ttagtttcat
     2041 gtttgtcctc tcggtttctc tatcttatat cccaaccccc aaactgtctt aatagtgggc
     2101 gtttggtcac tactatattt tgccagctcc tgtcgaagag catggatatg cacattcaag
     2161 gtattggtgt catccacgta gtcttctttc cagatctttt catagaggtc tgtcttggag
     2221 aaaactcgct ctggattgct agctaaaatc cacagcaatt caaatgattt aacagttaaa
     2281 tccagcattt cttctcctat ttgaacttca tgactactat gattcatttt tagattgcca
     2341 agggaaatca gctctgtttc gcccccacga tgaaggcggc gcaaaatatt gtggacacgc
     2401 aaaaccagtt cacgtgggct aaaaggctta gcaataaaat catctgctcc caagctcagg
     2461 ccgtaaatct tgtcctgttc actggtctta gcagtaataa ataggaaagg ctgctctggt
     2521 gataagtatt gaacctcact gattaaatca taaccatcca tccgaggcat catgacatct
     2581 gtgataatca aatcaatcgg ttttttcttg aacagctcta gcgcttccag tccatcatgg
     2641 gctaccaaga cctgataacc tgcctgaatt aagtatctct gatgaatatc tgtgatttct
     2701 acctcgtcgt caacgagtaa aattgtcttt cccatctgtc tctcctttga taaaaacagt
     2761 gctatactgc tttaagtata acactatttt tattgtttta cgatgatttt aatctgctat
     2821 tgaaagaaag tcctgattgc tgattgagtt gttaaactaa tcttagtcag cccactatcc
     2881 atcatttatt tccttagctg attagttttc ttcttttttg tttttcaaac ctagaccacc
     2941 gagtaaacct gcaagcgcaa gcccaagtaa accaatactt gccattgatg tttgagtctc
     3001 accagtattt ggtagcatag ctttatcctc tgacatcatc gtatcagaca tcttgttagc
     3061 agaagcagcc atgttttcac ctgccatcgt gttggtagaa cttgtcatgg tgtcagcagg
     3121 catgctatct gtagtacctg tagcatgatt gtgattcatc ggagtcacgc cagaaccaga
     3181 gttagaaggt gataatgaac catttgctgt gtctgatgtt tctttaacat ttatcttaat
     3241 agtgactttt ttagttgc
//
LOCUS       DAVBNN010000098         2999 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBNN010000098 DAVBNN010000000
VERSION     DAVBNN010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.098"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..173
                     /locus_tag="VQ847_002010"
     CDS             <1..173
                     /locus_tag="VQ847_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3051290.1"
                     /translation="DKAYNHALSKDRSKVENILAKVKTFKMFSTTYRNHRKRFGLRMN
                     LIAGIINHELGF"
     gene            254..970
                     /locus_tag="VQ847_002011"
     CDS             254..970
                     /locus_tag="VQ847_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3051291.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            1279..1704
                     /gene="rplK"
                     /locus_tag="VQ847_002012"
     CDS             1279..1704
                     /gene="rplK"
                     /locus_tag="VQ847_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3051292.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1912..2601
                     /gene="rplA"
                     /locus_tag="VQ847_002013"
     CDS             1912..2601
                     /gene="rplA"
                     /locus_tag="VQ847_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3051293.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT         1009 a          561 c          669 g          760 t
ORIGIN      
        1 aagataaagc ctataaccat gcgctatcta aggatagaag caaggttgag aacatccttg
       61 ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg
      121 gattacgaat gaatttgatt gctggtatta tcaatcatga actaggattc tagttttgca
      181 ggaagtctat taaaagatta gtcaaacgtt tatcatcaga agtagataaa ctattagaaa
      241 taaaggagta gaaatgaaga aaagatacct tgtcgtgaca gccttgctag ccttgagtct
      301 agcagcttgt tcacaagaaa aagcaaaaaa tgaagatggc acagctaaga cagaacagac
      361 agccaaagct gatgggacag tcggcagtaa gtctcaaggg gctgcccaga aaaaagcaga
      421 agtggtcaat aaaggtgatt actacagcat ccaaggaaaa tacgacgaaa tcatcgtagc
      481 caataaacat tatcctttgt cgaaagacta taatccgggg gaaaatccaa cagccaaggc
      541 tgagttggtc aaactcatca aagcgatgca agaggcaggt ttccctatta gtgatcatta
      601 cagtggtttt agaagttatg aaactcagac caagctctat caagattatg tcaaccaaga
      661 tggaaaggca gcagctgacc gttactctgc ccgtcctggc tatagcgaac accagacagg
      721 cttggccttt gatgtgattg ggactgatgg tgatttggtg acagaagaaa aagcagccca
      781 atggctcttg gatcatgcag ctgattatgg ctttgttgtc cgttatctca aaggcaagga
      841 aaaggaaaca ggctatatgg ctgaggaatg gcacctgcgt tatgtaggaa aagaagctaa
      901 agaaattgct gcaagtggtc tcagtttgga agaatactat ggctttgaag gcggagacta
      961 cgtcgattaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tacctactga
     1021 ctgcgtcggt tctattcaca acctcaaaac agtgttttga gctgacttcg tcagttttat
     1081 ctgcaatctc aaagctgtac tttgagcagc ctacagctag cttcctagtt tgctctttga
     1141 ttttcattga gtataaaaaa taaacttttc tcttgcaatt ccagataaat agtgtataat
     1201 ggatgggtat gtgaaaaaca tacttgtggg aggtaaaaat ctctaattac cgccaaaacc
     1261 acaaaggagg atttaaaaat ggctaaaaaa gtcgaaaaac ttgtaaaatt gcaaatccct
     1321 gctggtaaag ctacaccagc tccaccggtt ggacctgctc ttggtcaagc tggtatcaac
     1381 atcatgggat tcacaaaaga gttcaacgct cgtacagctg accaagctgg tatgatcatt
     1441 ccagttgtta tctcagttta cgaagataaa tcatttactt tcgttacgaa aacaccacca
     1501 gctgctgttc ttttgaaaaa agctgcaggt gttgaaaaag gatcaggtac acctaataaa
     1561 actaaagttg ctacagttac tcgtgcacaa gtacaagaaa ttgcagaaac taagatgcca
     1621 gatttgaacg cagcaaacgt agagtctgca atgcgtatga tcgaaggtac tgctcgttct
     1681 atgggattca ctgttgttga ctaatcaata acacagtaga aaatctcaca gcagtctatt
     1741 agttgctttt catactaggc aagtgactga ggcttgtact tgggtacagc aagggagctt
     1801 aaggccgtag gaagagaaaa atagtagact gaaaacccgc aagacttcat catttcgaga
     1861 agtgacgtgg gagatgaaaa tcgattgaac cacttacaag gagaatagaa aatggctaaa
     1921 aaaagcaaac aacttcgtgc tgctcttgag aaaatcgaca gcacaaaagc atacagcgta
     1981 gaagaagctg tagcacttgc aaaagaaact aactttgcaa aatttgacgc aactgtagaa
     2041 gttgcttaca acttgaacat cgacgttaaa aaagctgacc aacaaatccg tggagcaatg
     2101 gtattgccaa acggtactgg taaaacttca cgtgttcttg ttttcgcacg tggtgcaaaa
     2161 gctgaagaag caaaagctgc tggtgcagac tttgttggtg aagatgacct tgttgctaaa
     2221 atcaacgacg gttggttgga tttcgacgta gttatcgcta cacctgatat gatggctctt
     2281 gttggacgtc ttggacgtgt ccttggacca cgtaacttga tgccaaaccc taaaactggt
     2341 actgtaacaa tggatgttgc taaagcagtt gaagagtcta aaggtggtaa aatcacttac
     2401 cgtgctgacc gtgcaggtaa cgttcaagca atcatcggta aagtatcatt tgaagctgaa
     2461 aaattggttg aaaactttaa agctttcaac gaaacaatcc aaaaagcaaa accagctaca
     2521 gctaaaggaa cttacgtaac aaacttgact atcacaacta ctcaaggtgt tggtatcaaa
     2581 gttgacgtaa actcacttta atcagtagtt aaagtaatgt aaaaaagttg aagacgctat
     2641 gtctcaactt tttttgatat acgacgggca tgtcgtatat ctgaggtgta aatcctcggt
     2701 gggcacctac tactggtgaa cccaatagcg attcccaagt ctgactatcg tgaggtagcg
     2761 gattaaaacg gtctggggat agaccgtttt aagtctgacg ctggaaataa gaatcgtcag
     2821 aggaagggat agcgaaatcg tggctctacg aacaggaacg tgataataag gcctatatag
     2881 cggataaggt atctggctgg ggcgaccact atcaattata gtaaaatgaa ataagagtag
     2941 gacgaatcga tcagggcagc caaatcgatt tctaacaatg ttttagaaga agagatgta
//
LOCUS       DAVBNN010000099         2909 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBNN010000099 DAVBNN010000000
VERSION     DAVBNN010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.099"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ847_002014"
     CDS             complement(64..1005)
                     /locus_tag="VQ847_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3051294.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ847_002015"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ847_002015"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3051295.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          845 a          689 c          579 g          796 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccgta aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgacttg gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtca cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag cgtcgcctt
//
LOCUS       DAVBNN010000100         2633 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBNN010000100 DAVBNN010000000
VERSION     DAVBNN010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.100"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            423..2528
                     /locus_tag="VQ847_002016"
     CDS             423..2528
                     /locus_tag="VQ847_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3051296.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          847 a          474 c          610 g          702 t
ORIGIN      
        1 tttcatttta atatatagtt ttgagatggt tgatagaact gacgaagtca gctcaaaaca
       61 tggttttgag gttgtagata aggagaagct gatgtggttt gaagaggttt tcgaagagtg
      121 taaaaaaata ttggtcagtt aaagccaaaa ctcttgacct tttctgacca atgtagtata
      181 ttatgaacgt aaggtaaatg aaagccttac tagaacactt atttaaagta aaatagaaag
      241 aggtgggtct atgtttcatc tagaaatctt cagaagtaaa gatggtctac tcctgcttga
      301 aaaagaaaaa ccagaaatag tacgtagggt agcggtttaa ctagtctaaa ttttttaaaa
      361 caatggtcaa agatagtcaa tatcagtaat cataactaag taaacaaaaa gaggtaaaga
      421 atatgaataa caactttaat aattttaata acatggatga tttatttaac caattgatgg
      481 gtggtatgcg aggatatagt tctgaaaatc gccgttactt aattaatgga cgcgaagtca
      541 catctgagga atttgctcac tatcgtgcga ctggtcaatt accaggaaat gcagaaactg
      601 atgtgcaaat gccacaacag gcatcaggta tgaaacaaga cggtgtcctt gcaaaactag
      661 gtcgaaactt gacagcagaa gcgcgtgagg gtaagttgga tcctgttatc ggacgaaaca
      721 aggaaattca agaaacatct gaaatcctct cacgccgcac caagaacaat cctgttttgg
      781 tcggagatgc aggtgttggt aagacagcag ttgtcgaagg tctagcgcaa gccattgtga
      841 acggagatgt tcctgctgct atcaagaaca aggaaattat ttctattgat atctcaggtc
      901 ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa tgtccaaaac ttagtcaatg
      961 aagtgaaaga agcagggaat attatcctct tctttgatga aattcaccaa attcttggtg
     1021 ctggtagcac tggtggagac agtggttcta aaggacttgc ggatattctc aagccagctc
     1081 tctctcgtgg agaattgaca gtgattgggg caacaactca agacgaatac cgtaacacca
     1141 tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt gaaggtcaat gctccttcag
     1201 cagagaatac ttttaaaatt cttcaaggca ttcgtgacct ctatcaacaa catcacaatg
     1261 tcatcttgcc agacgaagtc ttgaaagcag cggtggatta ttctgttcaa tacattcctc
     1321 aacgtagctt gccagataag gctattgacc ttgtcgatgt aacagctgct cacttggcgg
     1381 ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga aatcgaaacg gaaaaagaca
     1441 agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc tctaaactat aaaacgcgca
     1501 ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga tatgaaagtg actgcaagtg
     1561 tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat cccagtatcg caaatgggag
     1621 cttcagatat cgaacgtttg aaagatatgg ctcatcgctt gcaagacaag gtgattggtc
     1681 aagataaggc cgtagaagct gtagctcgtg ctatccgtcg taaccgtgct ggttttgatg
     1741 aaggaaatcg cccaatcggc agcttcctct ttgtagggtc tactggggtt ggtaagacgg
     1801 agcttgctaa gcaattggca ctcgatatgt ttggaaccca ggatgcgatt atccgtttgg
     1861 atatgtctga atacagtgac cgcacagctg tttctaagct aattggtaca acagcaggct
     1921 atgtgggtta tgatgacaat agcaatacct taacagaacg tgttcgtcgc aatccatact
     1981 ctatcattct cttggatgaa attgaaaagg ctgaccctca agttattacc cttctcctcc
     2041 aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa tacagtaaac ttcaagaaca
     2101 ctgtcattat tgcgacctca aatgctggat ttggctatga agccaacttg acagaagatg
     2161 cggataaacc agaattgatg gaccgtttga aacccttctt ccgtccagaa ttcctcaacc
     2221 gctttaatgc agtcatcgag ttctcacact tgactaagga agacctttct aagattgtag
     2281 atttgatgtt ggctgaagtt aaccaaacct tggctaagaa agacattgac ttggtagtca
     2341 gtcaagcggc taaagattat atcacagaag aaggttacga cgaagtcatg ggggttcgtc
     2401 ctctccgtcg agtggttgaa caagaaattc gtgataaggt gacagacttc cacttggatc
     2461 atttagatgc taaacatctg gaagcagata tggaagatgg cgttttggtt attcgtgaga
     2521 aagcctaaga cagaattttg aggataaaaa agaaggagcc agctgaaaaa aactggttcc
     2581 tttctaggta cgacgggcat gtcgtgtagt aggttgaaac tagaatagta cac
//
LOCUS       DAVBNN010000101         2535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBNN010000101 DAVBNN010000000
VERSION     DAVBNN010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.101"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ847_002017"
     CDS             <1..559
                     /locus_tag="VQ847_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3051297.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ847_002018"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ847_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3051298.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2029
                     /locus_tag="VQ847_002019"
     CDS             1424..2029
                     /locus_tag="VQ847_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3051299.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2535)
                     /locus_tag="VQ847_002020"
     CDS             complement(1977..>2535)
                     /locus_tag="VQ847_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3051300.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          864 a          363 c          439 g          869 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgaac aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtctt ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacactg agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa actcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccaaggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tgttc
//
LOCUS       DAVBNN010000102         2481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBNN010000102 DAVBNN010000000
VERSION     DAVBNN010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.102"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ847_002021"
     CDS             complement(173..838)
                     /locus_tag="VQ847_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3051301.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ847_002022"
     CDS             complement(852..2231)
                     /locus_tag="VQ847_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3051302.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          813 a          565 c          463 g          640 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt c
//
LOCUS       DAVBNN010000103         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBNN010000103 DAVBNN010000000
VERSION     DAVBNN010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.103"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ847_002023"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ847_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3051303.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ847_002024"
     CDS             1681..>2364
                     /locus_tag="VQ847_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3051304.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          831 a          431 c          476 g          626 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgactct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBNN010000104         2140 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBNN010000104 DAVBNN010000000
VERSION     DAVBNN010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.104"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            71..609
                     /locus_tag="VQ847_002025"
                     /pseudo
     CDS             71..609
                     /locus_tag="VQ847_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            676..1086
                     /locus_tag="VQ847_002026"
     CDS             676..1086
                     /locus_tag="VQ847_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3051305.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1202..>2140
                     /gene="pavB"
                     /locus_tag="VQ847_002027"
     CDS             1202..>2140
                     /gene="pavB"
                     /locus_tag="VQ847_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET3051306.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSI"
BASE COUNT          655 a          411 c          476 g          598 t
ORIGIN      
        1 cgacgttgac gcggtttgaa gagattttcg aagagtataa gaaaaaatca gtcccctaaa
       61 ggagcagatt atgaagttat tgtctatcgc catttctagc tataatgcag cagcctatct
      121 tcattactgt gtggagtcgc tagtgattgg tggtgagcaa gttgggattt tgattatcaa
      181 tgacgggtct caggatcaga ctcagaaatc gctgagtgtt tagctagcaa gtatcctaat
      241 atcgttagag ccatctatca ggaaaataaa ggccatggcg gtgcggtcaa tcgtggcttg
      301 gcagaggctt ctgggcgcta ttttaaagta gttgacagtg atgactgggt ggatcctcgt
      361 gcctacttga aaattcttga aaccttgcag gaacttgaga gcaaaggtca agaggtggat
      421 gtctttgtga ccaattttgt ctatgaaaag gaagggcagt ctcgtaagaa gagtatgagt
      481 tacgagtcag tcttgcctgt tcggcagatt tttggctggg accaggtcgg aaatttctcc
      541 aaaggccagt ataccatgat gcactcgctg atttatcgga cagatttgtt gcgtgctagc
      601 cagttctaac tgcctgaaca tactttttat gtcgataatc tctttgtctt tacgcccctt
      661 cagcaggtca agaccatgta ctatctgcct gtcgatttct atcgttattt gattgggcgt
      721 gaggaccagt ctgtcaatga gcaagtgatg attaagtgca ttgaccagca actcaaggtc
      781 aatcgactct tggtagacca acttgatttg tcccaagtga gtcatcccaa aatgcgagaa
      841 tatctgctga atcatattga aatcacgacg gtgatttcca gtaccctgct caaccgatct
      901 ggaacagcgg agcatctggc aaaaaaacgc caattgtgga cctatattca gcagaaaaat
      961 ccagaagtct ttcaggctat tcgtaagacc atgttgagcc gtttgaccaa acattctgtc
     1021 ttgccagatc gcaaactgtc caatgtcgtc tatcaaatca ccaaatctgt ttatggattt
     1081 aattaatata agtgttttat aagagggatt taagaaaaat tttaactttt tcttagtcct
     1141 ttttaatttc aggagattat actagagtca tcaaataaag aaagactcta aggagaatcc
     1201 tatgaaattc aatccaaatc aaagatatac tcgttggtct attcgccgtc tcagtgtcgg
     1261 tgttgcctca gttgttgtgg ctagtggctt ctttgtccta gttggtcagc caagttctgt
     1321 acgtgccgat gtggtcaatc cgaccccagg tcaagtctta cctgaagaga catcgggaac
     1381 gaaagagggt gacttatcag aaaaaccagg agacaccgtt ctcactcaag cgaaacctga
     1441 gggcgttact ggaaatacga attcacttcc gacacctaca gaaagaactg aagtgagcga
     1501 ggaaacaaac tcttctagtc tggatacact ttttgaaaaa gatgaagaag ctcaaaaaaa
     1561 tccagagcta acagatgtct taaaagaaac tgtagataca gctgatgtgg atgggacaca
     1621 agcaagtcca gcagaaacta ctcctgaaca agtaaaaggt ggagtgaaag aaaatacaaa
     1681 agacagcatc gatgttcctg ctgcttatct tgaaaaagct gaagggaaag gtcctttcac
     1741 tgccggtgta aaccaagtaa ttccttatga actattcgct ggtgatggta tgttaactcg
     1801 tctattacta aaagcttcgg ataatgctcc ttggtctgac aatggtactg ctaaaaatcc
     1861 tgctttacct cctcttgaag gattaacaaa agggaaatac ttctatgaag tagacttaaa
     1921 tggcaatact gttggtaaac aaggtcaagc tttaattgat caacttcgcg ctaatggtac
     1981 tcaaacttat aaagctactg ttaaagttta cggaaataaa gacggtaaag ctgacttgac
     2041 taatctagtt gctactaaaa atgtagacat caacatcaat ggattagttg ctaaagaaac
     2101 agttcaaaaa gccgttgcag ataacgttaa ggacagtatc
//
LOCUS       DAVBNN010000105         1912 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBNN010000105 DAVBNN010000000
VERSION     DAVBNN010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.105"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ847_002028"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ847_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>1912)
                     /gene="phtB"
                     /locus_tag="VQ847_002029"
     CDS             complement(1202..>1912)
                     /gene="phtB"
                     /locus_tag="VQ847_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3051307.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPNEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESP
                     EESPEESEEPQVETEKVKEKLREAEDLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDN
                     NTIMAEAEKLLALLKESK"
BASE COUNT          557 a          388 c          293 g          674 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctctt
     1501 ctcgaggggt ttcttcctca ggtttttctg tctgaggttt ctcctcgttt ggtttttccg
     1561 tttgattggt atcagcttga ccatttttgt ttctttgaac atggtcgcta gcgttaccaa
     1621 aaccattatc tgaatgcgga cgttcgtttg gatgttcgac atagtacttg acagtcgcca
     1681 aaagatcctc aagactatac cccttaggtg cctcataaag gccttcgtca aaccactcaa
     1741 atttgatgtt atggtaatgg tcataatgag gtatgattaa actaccgttt ttgacttcta
     1801 cagtatattg aagattgtaa ggcatacgat caagtggcac cttcttagct gctttcacgc
     1861 ggttgtagat agcttctgct ccttttgcct cagtatttcc tgaatcctga tg
//
LOCUS       DAVBNN010000106         1871 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBNN010000106 DAVBNN010000000
VERSION     DAVBNN010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.106"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..919)
                     /locus_tag="VQ847_002030"
     CDS             complement(<1..919)
                     /locus_tag="VQ847_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3051308.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLD"
     gene            complement(1364..1762)
                     /locus_tag="VQ847_002031"
     CDS             complement(1364..1762)
                     /locus_tag="VQ847_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3051309.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          506 a          380 c          326 g          659 t
ORIGIN      
        1 agtccaagca ttttttagga tagttgttaa tccacttttc gatgaatgcg acttctttgg
       61 gagtcatttt cttggttccc ttaggtaacc atctacgaat gaacctgttg tgattctcat
      121 tagttcccct ttcccaagag gcataggggt gcgcataata aatgtgctcc tcagaaaata
      181 catcagacaa gcgattgaat tccgttccat tatctgccgt gatggaaaga atcttgtgtt
      241 gttttaagat gagttttaga gcctgattga ccacctcagc acttttattt ggaatcaatc
      301 ggatgatctg atgtctactc tttcgatccg tcaagacaag caagcagtag tttttcgctc
      361 tcgtaagtag aaccgtatca atctcataat gcccattctc caagcgaaga ttgatagctt
      421 caggccgctg tgcgatggat tgaccagcag gtttaaagtt ggtgctggcc tgtttcttaa
      481 gcgcttttcc ttttctaggg taaggcaaat cctgcttgct taaccccaat tttccatgat
      541 gaatccaata gtaaatggtt gaaattccca cgttaacccc tttagccatc accatcattt
      601 caggcgaaaa tttttggtta tgatagtgga gaatcttttc ctttagttcc ttggtcaagc
      661 ttgatttctt gaccgagcgc ttgcgattgt tttcataaga ctgttgagcg tagtcggcag
      721 aataaacctc tttgaagcgc ccttttccaa gacattgtcg gactgtccca cgcttgattt
      781 cagtgtggat agtttgagga gcttttccaa gtagagaggc aacttctcta tttgattttc
      841 cttctttttt ccatctttcg attaagcgac ggctatcgat tgtcaaatgt ttaccttttg
      901 tagtataatt gtcttgcatt tctgtgcctt tcttgtgttt gtggttgaac aacaagtata
      961 acacagaggt gttttcttat gcctacaaga gctttcatta tttccatttt cttttggatt
     1021 tcactctatt ctgaaaaact tgtgtatatt tactgaagct agcaagtctt acctgtaaat
     1081 ttaatgaaag caacacaaaa ttcgagaggg gaatctcgga ttaatagata gagagttttt
     1141 agtttaaata aattgtttaa aatatcaaca acatcacttc ttttcttaac ctgataagtc
     1201 ttgattccta attttggggc tacgattata ttgtcctcaa tatcgtctag aaagacacaa
     1261 tttctaggtt ataactggta tttatcgata gttactcata tacatcagtc cacctccata
     1321 cttatgtgcg agcctctctt tgtattatac ctccatactc accttacaga ttcttttggt
     1381 aataatatct ttgcctaatg tagagatagt cttgcaaaga aaaaacttcc ttgtagccat
     1441 gtttctgata aaagtccggt gcctggaact ggtaagtatt gacaaaggca aaacaacaat
     1501 ttcgattctt agcttcactt tctgcctgtt gcaatagttt tgaaccgatt ccttgccctc
     1561 gcagttcctc ttttacaaac aaatactcga tttctagcca atttccaaaa gtctctgcta
     1621 tcaaacctgc caggagattg cccttttcat cttcgacata aagattaagt ggctcacttt
     1681 cagcctcttc tctttttgaa cggttataaa cacgaatcag attccctatt tcttgcgatt
     1741 tatgtgattc cttattttcc aatctaatga aatgaaataa aacatgcgca aatcgattaa
     1801 ggaatttaat ctaatttcta acaatgtctt agaaatcaaa gtgtactatt ttaacttcaa
     1861 tgcactatac a
//
LOCUS       DAVBNN010000107         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBNN010000107 DAVBNN010000000
VERSION     DAVBNN010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.107"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ847_002032"
     CDS             complement(3..968)
                     /locus_tag="VQ847_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3051310.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ847_002033"
     CDS             complement(1086..1499)
                     /locus_tag="VQ847_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3051311.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ847_002034"
     CDS             complement(1496..1732)
                     /locus_tag="VQ847_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3051312.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBNN010000108         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBNN010000108 DAVBNN010000000
VERSION     DAVBNN010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.108"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ847_002035"
     CDS             complement(242..1006)
                     /locus_tag="VQ847_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3051313.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ847_002036"
     CDS             1228..1524
                     /locus_tag="VQ847_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3051314.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          522 a          404 c          316 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg atgaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBNN010000109         1394 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBNN010000109 DAVBNN010000000
VERSION     DAVBNN010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.109"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            268..1278
                     /gene="ccpA"
                     /locus_tag="VQ847_002037"
     CDS             268..1278
                     /gene="ccpA"
                     /locus_tag="VQ847_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3051315.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          439 a          228 c          317 g          410 t
ORIGIN      
        1 attttactat aactttagga gggcttagtt tcctcctttt tgtttagtct aaggtggtag
       61 caaggagcta aacctaggtt ttctatgaaa ttttttcaat caatcttcaa aaaacacttg
      121 aaagtgttta caattagtga tagaatggaa taagtagaaa tatgaaaacg aaattttcac
      181 atcttcactt ttgtaagtag atatagagct tcaatcagca cctctacttg taaaagaata
      241 tgtgagatag aaaggacagg aaaaggaatg aatgcagatg atacagtaac catttatgat
      301 gtcgctcgtg aagcaggtgt ttccatggcg acggtcagcc gtgtggtcaa tggcaataaa
      361 aatgtaaaag agaatacccg taaaaaagtg ctagaggtaa ttgatcgttt ggattatcgt
      421 ccaaatgcag ttgcgcgtgg tcttgcaagt aaaaagacaa ccactgtcgg tgtcgtgatt
      481 ccaaatatta ccaatggtta tttttcgagt ttggctaagg ggattgatga tattgcagaa
      541 atgtacaagt acaatattgt cctagctaat agcgatgaag ataacgagaa agaagtttct
      601 gttgtcaata ccctcttttc aaagcaggta gatggcatta tctatatggg ttatcacttg
      661 acagataaaa ttcgctcaga attttcgcgc tcacgtactc cgattgttct cgcaggaact
      721 gtcgatgttg agcaccagtt gccaagtgtc aatattgact ataagcaagc aacaattgat
      781 gcagtgagtt accttgctaa agaaaatgag cgtattgctt tcgttagcgg tccgctagtg
      841 gatgacatca atggtaaggt tcgtttagtt ggctacaagg aaaccttgaa aaaagcagga
      901 atcacttata gtgagggttt ggtatttgaa tctaaatata gctatgatga tggttacgcc
      961 ttagcagagc gtttgatttc atcaaatgca actgcagcag ttgtgacagg tgatgagttg
     1021 gcagcaggag tcttgaacgg tttggctgat aaaggtgttt ctgtgccaga agattttgaa
     1081 attattacta gtgatgattc acaaatctca cgctttaccc gtccaaactt gacaacgatt
     1141 gcccaacctc tttatgacct tggtgctatt agtatgcgta tgttgaccaa gattatgcat
     1201 aaggaagagt tggaagaacg tgaagttctc ttacctcatg gtttgacaga acgtagctca
     1261 acacgaaaac gtaaatagaa aaaatcaggg aatcgagaag atttcctgat tttgtgctct
     1321 taaacaagag atgttgactt aatgaatacc atagagcgga ctaggcggct ggttaaaggc
     1381 tgcgcaacac actg
//
LOCUS       DAVBNN010000110         1048 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBNN010000110 DAVBNN010000000
VERSION     DAVBNN010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.110"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ847_002038"
     CDS             84..491
                     /locus_tag="VQ847_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3051316.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            656..955
                     /locus_tag="VQ847_002039"
     CDS             656..955
                     /locus_tag="VQ847_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3051317.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          371 a          213 c          182 g          282 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat ttaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaggtgc cgaaatgaac tgcacccc
//
LOCUS       DAVBNN010000111         1029 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBNN010000111 DAVBNN010000000
VERSION     DAVBNN010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.111"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(225..515)
                     /locus_tag="VQ847_002040"
     CDS             complement(225..515)
                     /locus_tag="VQ847_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3051318.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(503..755)
                     /locus_tag="VQ847_002041"
                     /pseudo
     CDS             complement(503..755)
                     /locus_tag="VQ847_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
BASE COUNT          303 a          193 c          143 g          390 t
ORIGIN      
        1 gtggatgttt ctggtctaaa gtcatctgaa tctttgagat gagctttata aatcgctttt
       61 ttcagttttt gcactggtgt ttcgataaac tcaaactttt tagccgtggt attgcctgat
      121 tttatagtat attgaaacta gaatagtaca cctctacttc taaaacattt ttagaaatcg
      181 atttgactgt cctgatcgat ttgtcctgtt cttatttcat tttactatat ttgagccact
      241 tcgtctttaa cggctttatt cataagctct tgtaattttt ctttactatc aattacttct
      301 gattttccgt tgtaatttat tgtaataggt tttaacttac ctaatttctc gacacgctca
      361 gaaatttgat cttttttgaa ggctgcatat gtttttccta agattttttc gaaaatatat
      421 ttatcagata gcggtttgcc ttcttcttca gcttggtttt tgtattgatt tgaaacataa
      481 ggaacaaatc cttcatagta acctaatgct cccataagtt caaaagcttg ttttctaatt
      541 caaaccattg caactcagat ttcagctttt cagataaatc ctgctcatcc aaataatgac
      601 ttgaaattag tgctgaactc gtttctgtat cctgtacagg ctgagcaccc ataccagcaa
      661 aaaaataaac tcgttcctag caagaccgaa caagctccta ttgcatattt cctcaaagaa
      721 aaacgctgct ttctctcaaa ttgaaattct ttcatcccat ctcccatcat tcattattac
      781 tgtatatttt gtatatcaga aatagtttgt attcacaaat ctttctagtt attcccttat
      841 cattcctaat taagggagat aacatacaat aatttttagt taaatgtata tcgatgtttt
      901 ttgtttttct taataaacgc aatacaaaaa gagcctgttg ccaagctctt tatactcaat
      961 gaaaatcaaa gagcaaacta ggaaactagc cacaggttgc tcaaaacacc gttttgaggt
     1021 agtagataa
//
LOCUS       DAVBNN010000112          864 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBNN010000112 DAVBNN010000000
VERSION     DAVBNN010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.112"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            463..>864
                     /locus_tag="VQ847_002042"
     CDS             463..>864
                     /locus_tag="VQ847_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3051319.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGN"
BASE COUNT          297 a          136 c          157 g          274 t
ORIGIN      
        1 tctatcctat cttctagaat gtcttccaaa cgtggaaact ctcgtaaaca aagaggtttt
       61 agaggcctat ttaccgtgga ctaaagttgt acaagaaaag tgcaaataag aaatctccag
      121 attaggaact atatatgagt tcactaatct ggagattttt caatagactt cgttattgga
      181 cggttacgat atgatcactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg
      241 aacaacctgc ggctagcttt ctagtttgct ctttgatttt cattgaatat tagaacagca
      301 aaaatgcttg gagtatttgt ttgtgtgttt gtttttatat aacaaactat aaacaaaaca
      361 aaaatataaa aaaagagaca aaaaagaaca gaaagtaatt gacaacggtt tcatatagtg
      421 ttatacttat ggcataaagt taatggaaag aagggaaaac ttatggtatt agattatttc
      481 tttgacaaaa accttgtgtt ttgcttagaa gcggataatc aagaacaact ctttgatcag
      541 gttgcaactt tattggaaga acgagaaatt gtcactccaa cttatcgtga agccttgatc
      601 acgcgtgaaa agtcatttcc aactggttta gatatggaat ttctaggaaa ggacttgcca
      661 aatgtagcga ttcctcatac agatattgtt cataatctag ctgagaaagt ggtggttgtt
      721 cgattagaaa aaccagtaac ttttcacaat atgatagctc ctgataagga agtagaagta
      781 tccttgctct tctttatcat caataactca agttcaagtc aaacaaatat tctggctcag
      841 ttgatggact ttttcacagg aaat
//
LOCUS       DAVBNN010000113          848 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBNN010000113 DAVBNN010000000
VERSION     DAVBNN010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.113"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(1..848)
                     /locus_tag="VQ847_002043"
                     /pseudo
     CDS             complement(1..848)
                     /locus_tag="VQ847_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          273 a          143 c          176 g          256 t
ORIGIN      
        1 tccgaaaaat ttctctggtt ccttattctg gaaatgaaaa agcaagagct gatagagttg
       61 atagtggtgt ttcaagtctt ccgaataact caaaagcttg tttaaaatct ctttattggt
      121 tcaatgcata cgaaaagtag gacgataaaa atgtttatca ctcagtttac gactatccta
      181 ttgaatgagt ttccagtagc gcttgatagc cttgtattca tgggattttc gatgaaactg
      241 atttatgatt tgaacacgca cacgactcat agcacggcta agatgttgta caatgtgaaa
      301 gcgatccaac acgattttag cattcgggag tgaaacagtc tgggagactg tttcagcctg
      361 agcctagaaa tttgaaagcg aaactgttta gccaagtcat agtaagggct aaacatatcc
      421 atagtaatga ttttgacgcg acatcggaca actctatcgt agcgaagaaa gtgatttcga
      481 atgatagctt gtgttctacc ctcaagaaca gtgatgatat tgagattgtt aaaatcttgc
      541 gcaatgaagc tcatctttcc ctttgtaaaa gcatactcat cccaagacat aatctcagga
      601 agacaagaaa aatcatgttt aaagtgaaaa tcattgagct tacgaataac agttgaagtt
      661 gagatggaaa gctgatgggc aatatcagtc atagaaatct tttcaattaa cttttgagca
      721 atcttttggt tgatgatacg agggatttgg tgattcttct tgacgataga agtttcagcg
      781 accatcattt ttgaacagtg atagcacttg aatcgacgct ttctaaggag aattctagta
      841 ggcatacc
//
LOCUS       DAVBNN010000114          765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBNN010000114 DAVBNN010000000
VERSION     DAVBNN010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.114"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ847_002044"
     tRNA            complement(74..147)
                     /locus_tag="VQ847_002044"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ847_002045"
     tRNA            complement(157..242)
                     /locus_tag="VQ847_002045"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ847_002046"
     tRNA            complement(250..321)
                     /locus_tag="VQ847_002046"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ847_002047"
     tRNA            complement(344..416)
                     /locus_tag="VQ847_002047"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ847_002048"
     tRNA            complement(435..516)
                     /locus_tag="VQ847_002048"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ847_002049"
     tRNA            complement(522..594)
                     /locus_tag="VQ847_002049"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ847_002050"
     tRNA            complement(619..691)
                     /locus_tag="VQ847_002050"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..765)
                     /locus_tag="VQ847_002051"
     tRNA            complement(694..765)
                     /locus_tag="VQ847_002051"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          195 a          225 c          168 g          177 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcc
//
LOCUS       DAVBNN010000115          759 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBNN010000115 DAVBNN010000000
VERSION     DAVBNN010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.115"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..>759
                     /locus_tag="VQ847_002052"
     CDS             <1..>759
                     /locus_tag="VQ847_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3051320.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          297 a          110 c          121 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaagg
//
LOCUS       DAVBNN010000116          756 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBNN010000116 DAVBNN010000000
VERSION     DAVBNN010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.116"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ847_002053"
     CDS             3..305
                     /locus_tag="VQ847_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3051321.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..756
                     /locus_tag="VQ847_002054"
                     /pseudo
     CDS             313..756
                     /locus_tag="VQ847_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          250 a          141 c          155 g          210 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat tattctggta aaaagaaatt
      721 tcacgctatg aaggctcaag cgattgtcac aagtca
//
LOCUS       DAVBNN010000117          752 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBNN010000117 DAVBNN010000000
VERSION     DAVBNN010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.117"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            250..590
                     /gene="tnpB"
                     /locus_tag="VQ847_002055"
                     /pseudo
     CDS             250..590
                     /gene="tnpB"
                     /locus_tag="VQ847_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(623..752)
                     /locus_tag="VQ847_002056"
                     /pseudo
     CDS             complement(623..752)
                     /locus_tag="VQ847_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          231 a          147 c          133 g          241 t
ORIGIN      
        1 aatttcataa taaaaacacc ccaaaagtta gattttttct gtctaacttt tggggggcag
       61 ttcattctac acccactatt atgcgttttt atcattttga aatctactgc taatcaatga
      121 agaagcaaag atcaaactag gcagctagtt acaagttacg taagcgcgtc ataacaaggt
      181 atctatccta attccccaac ttccagtata ctagataaaa aataattatc ggaggaaagg
      241 tattgtacta tgataattca actaagtgat ttaggtcaag ttcaccttgt ttgtagcaag
      301 atagatatga ggcagggaat agactcatta gcctatgtag ttaaaaccca ctttgaattg
      361 gatcctttct ccggtcaagt ctttctcttt tgtggtggac gtaaagaccg ctttaaagcc
      421 ctttactggg atggtcaagg attttggcta ctatataaac gctttgagaa cggcagactg
      481 acttggccca gtacagaaaa ggatgtcaaa gctctcacac ctgaacaagt agactggctt
      541 atgaagggct tttctatcac tccaaaaata aatccatcag aaagtcgtga tttctattga
      601 aatgaggact ttctttttat actcatctgc tttcaaaaag cattctagtc catctccgat
      661 taacgatggg ctttatcacc tccttctcca gtccttgtat gatatcttaa agttgattca
      721 tgacatcttc caaagtttga aaggctttat tt
//
LOCUS       DAVBNN010000118          632 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBNN010000118 DAVBNN010000000
VERSION     DAVBNN010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.118"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            49..410
                     /locus_tag="VQ847_002057"
                     /pseudo
     CDS             49..410
                     /locus_tag="VQ847_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
BASE COUNT          208 a           76 c          120 g          228 t
ORIGIN      
        1 gaggctagtt tcctagtttg ctctttggtt ttcattgagt ataacacatt gttagaagtt
       61 ggtttaaatt tcctaatcag tttgttcaca tttaccttcg atatattata tcccatagtt
      121 aaggttggtc atacagatga ttatagtcat ggagccgtaa aacttagtgt ttctttagtt
      181 gacaaagatg ccatgaaaaa atatctgtaa ctgtaatagg atattttgaa ataaatatag
      241 atgaaaatat caccgatatt ctatacgtaa atggtactgc tattctttgt ccttatttac
      301 gttctattgt ttcaatagtt tcggcaattg atagcagtga agcaatgttg ctacctacca
      361 ttaatgtttt agagttacta gataaatctc aaccttttga agaagaataa tttattagct
      421 cactaaattg agggtaagga aaagtaaaag cagtaagaaa aatgtcttgc attatacagc
      481 aaccttttgg gaatgagtag atggattgaa taaaatttga ttaagagtgg atgatttatc
      541 tgtagattat tattggacag ttagtcttga agtagtctaa gaattaggtt ataatcagta
      601 gaagccttgc taataatgag gaggttagtt ta
//
LOCUS       DAVBNN010000119          604 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBNN010000119 DAVBNN010000000
VERSION     DAVBNN010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.119"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ847_002058"
     CDS             complement(21..500)
                     /locus_tag="VQ847_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3051322.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          161 a          140 c           81 g          222 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca caaaaaagag
      601 aggc
//
LOCUS       DAVBNN010000120          601 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBNN010000120 DAVBNN010000000
VERSION     DAVBNN010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.120"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..>601
                     /locus_tag="VQ847_002059"
     CDS             <1..>601
                     /locus_tag="VQ847_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3051323.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT          192 a          135 c          122 g          152 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattcatcaa gatttacttg ataataaagg tcgacaagtt gattttgagg
      541 ctttggataa cctgttggaa cgactcaagg atgtctcaag tgataaagtc aagttagtgg
      601 a
//
LOCUS       DAVBNN010000121          588 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBNN010000121 DAVBNN010000000
VERSION     DAVBNN010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.121"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..206)
                     /locus_tag="VQ847_002060"
     CDS             complement(<1..206)
                     /locus_tag="VQ847_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3051324.1"
                     /translation="MNYEASKQLTDARFKRLVCVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTY"
     gene            201..455
                     /locus_tag="VQ847_002061"
     CDS             201..455
                     /locus_tag="VQ847_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3051325.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT          189 a           86 c          117 g          196 t
ORIGIN      
        1 tcataagtgc gatattctcg cacatattga agagtggcca taagaaggtc ttctaggctt
       61 aatttaggtt ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt taatacagct
      121 aatatctctt caaaagtcgt gcgctgaaca caaacaagac gcttaaatcg tgcatcagtt
      181 agttgtttac ttgcttcata attcatagaa ctactatacc atattttgtt tcgcaggaag
      241 tctattggaa agtaagaaat attggagctg aggcgattag aagaaattgt gagcgtggtg
      301 ctattttttc aggtaaaata aaacatcacg aagattctca gtttaaagga gagcactatg
      361 ttgaatgtta tgctgtttta gataatacgg ttatagcaag agatagaata acagtcccta
      421 tcgatccgtt atgtggaaaa gattttatag agtagcatat aattgattct taactggaat
      481 actctctatc tctttacatc aagaaaatga ctaaacaggg aagtttgcct tcttcccttt
      541 ttttgttata ctagtagaag aaaaaaatag aaagatttgt gggagtga
//
LOCUS       DAVBNN010000122          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBNN010000122 DAVBNN010000000
VERSION     DAVBNN010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.122"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ847_002062"
     CDS             complement(<1..534)
                     /locus_tag="VQ847_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3051326.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBNN010000123          535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBNN010000123 DAVBNN010000000
VERSION     DAVBNN010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.123"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..110)
                     /locus_tag="VQ847_002063"
     CDS             complement(<1..110)
                     /locus_tag="VQ847_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3051327.1"
                     /translation="MVNCEPLEAYRQLAEAELVGCWAHVRRKFFEATPKQA"
     gene            complement(183..410)
                     /locus_tag="VQ847_002064"
     CDS             complement(183..410)
                     /locus_tag="VQ847_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3051328.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
BASE COUNT          155 a          125 c          108 g          147 t
ORIGIN      
        1 gcttgcttgg gggtcgcttc aaaaaatttc cttctcacat gcgcccaaca tccaacaagt
       61 tcagcttctg ccagttgacg ataagcttct agcggttcgc agtttaccaa gcttagcgtc
      121 gccttgctcc taaaccttgg actgctatcg cataggcaga actagaggac taaagtccta
      181 agttactgcc gcaacatatc acaatgaaca tagccagaat aatctcctag gaattcttgt
      241 actaccgaac cactccgact ctgatcatga tggtacagcg tgattgcttg attctcaact
      301 ttcccagaca aaaaggtcca atagtaggtc agatggctat gactctctag aacccgataa
      361 gaagtttcat ccgcatgaag taagggctga gtcaatagtc tctctcgcaa gaggttataa
      421 aggggcttta ggaataggag ctttcacaag cttatccaga tgattatctt ttactcgtta
      481 tggacaatgc tatatggcat aaatcaagta ccttaaagat tccgactaat attgg
//
LOCUS       DAVBNN010000124          520 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBNN010000124 DAVBNN010000000
VERSION     DAVBNN010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.124"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            1..520
                     /locus_tag="VQ847_002065"
                     /pseudo
     CDS             1..520
                     /locus_tag="VQ847_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          199 a           88 c          108 g          125 t
ORIGIN      
        1 atcgttacta ttctcctgat ttaaaacaag aaatgattca taaagtctga catgaaggct
       61 agactaaaga tagagtttct cttgaatacg gtctcccaag tcgtacgata cttcttaact
      121 ggctagcaca atacaggaaa aacgggtata ctattgttga gaaaccaaga gggagagtac
      181 ctaaaatggg acgtaagcca agaacgagac ctgaagagag gacagaatta gaacgtcttc
      241 aagcagaaaa tgagtacctg agagcggaga atgccatcct aaaaaagtta agagaactcc
      301 gattgaagga ggaaaaagag aaagaagaaa gatagaaatt gttcaagaat taatgactga
      361 gttttcgtta gatcttcttc taaaagccat taaactagct cgttggacct actactatca
      421 cttgaaacag ttagacaaac cagataagga ccaagagctt aaagctgaaa ttcaattcat
      481 ttttatcgaa cacaagggaa attatactta tcgccgggtt
//
LOCUS       DAVBNN010000125          508 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBNN010000125 DAVBNN010000000
VERSION     DAVBNN010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.125"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            1..508
                     /locus_tag="VQ847_002066"
                     /pseudo
     CDS             1..508
                     /locus_tag="VQ847_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT          153 a           99 c          114 g          142 t
ORIGIN      
        1 tgaggagttc ggactcgact ctctccttca agaaacacgt ggtggtcgta accatgcata
       61 tatgacagtt gaggaagaga aagcctttct tgcccgccat ttgaaggcta cagaggcagg
      121 agaatttgtt acaattgatg ccttatttca ggcttataaa aaggagttag gtcattccta
      181 cacacgtgat gccttctatc aactgttgaa gcgccatggt tggcgaaata ttacgccacg
      241 tccagaacat cctaagaaag cagacgctca aaccattgtt gcgtctaaaa ataaaatctc
      301 aattcaagaa gacaagaaag cgttttaaat atagtagacg ttttcataag gttcgcttga
      361 tgtaccaaga tgaggctggt ttcggtagaa tcagtaaact gggatcttgt tggtctccaa
      421 taggagtagg tccacatgtc catagtcact atatacgaga atttcgctat tattatggag
      481 ctgttgatgc ctatacaggc gaatcatt
//
LOCUS       DAVBNN010000126          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBNN010000126 DAVBNN010000000
VERSION     DAVBNN010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.126"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ847_002067"
     CDS             <1..>501
                     /locus_tag="VQ847_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3051329.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBNN010000127          486 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBNN010000127 DAVBNN010000000
VERSION     DAVBNN010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.127"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            377..486
                     /locus_tag="VQ847_002068"
                     /pseudo
     CDS             377..486
                     /locus_tag="VQ847_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          194 a           74 c           76 g          142 t
ORIGIN      
        1 ctaaaatcaa aaagcattat ataatagtga tatgaaatca actaaagaag aaatccaaac
       61 catcaaaaca cttttaaaag actctcgtac agctaaatat cataaacgcc ttcaaatcgt
      121 tctatagtaa aatgaaataa gaacagtaca aatcgatcag gacagtcaaa ttgatttcta
      181 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tctattatat ttcgtctgat
      241 gggcaaatct tataaagaga ttatagaact tttatagtag tttgaaataa gatgtgaaca
      301 actctatcag gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt
      361 atagattcaa tacactatag actgtaatca aacaacgatt tggcgaaatg taaaaaaata
      421 tgaggagttc ggactcgact ctctccttca agaaacacgt ggtggtcgta accatgcata
      481 tatgac
//
LOCUS       DAVBNN010000128          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBNN010000128 DAVBNN010000000
VERSION     DAVBNN010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.128"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(372..446)
                     /locus_tag="VQ847_002069"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ847_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBNN010000129          397 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBNN010000129 DAVBNN010000000
VERSION     DAVBNN010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.129"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..>397)
                     /locus_tag="VQ847_002070"
     CDS             complement(<1..>397)
                     /locus_tag="VQ847_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3051330.1"
                     /translation="KTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETL
                     YQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKE
                     MKEGFFGDKTDSSTLIKNEVRMMMSCIAYN"
BASE COUNT          101 a           83 c           93 g          120 t
ORIGIN      
        1 gattgtaggc gatacagctc atcatcatac gaacttcgtt tttgattaag gttgaactat
       61 ccgttttatc gccaaaaaat ccctccttca tctccttgat gaaattctcg gcttgaccac
      121 gtccacgata aagctgaaac tggtcttggc ttgttccact cgtcatattt gtaacgagag
      181 aaataacatc gtagaacaag tttccttctt ttcgttcaga gaactggcag acacgacgct
      241 tgtgcgacca agatcctgct tgatagagag tttctgagta ggcggagtgg ggcaagatgg
      301 ttaagtcctc atcctgtggg caagggaggg aaaggtctcc aagacggctc agaacagtat
      361 ttttcttgag ttttatgagg tagtattgcc ctgtttt
//
LOCUS       DAVBNN010000130          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVBNN010000130 DAVBNN010000000
VERSION     DAVBNN010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.130"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ847_002071"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ847_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBNN010000131          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVBNN010000131 DAVBNN010000000
VERSION     DAVBNN010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.131"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ847_002072"
     CDS             116..>297
                     /locus_tag="VQ847_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3051331.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBNN010000132          288 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVBNN010000132 DAVBNN010000000
VERSION     DAVBNN010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.132"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
BASE COUNT          100 a           55 c           56 g           77 t
ORIGIN      
        1 catggcaagc cgacgctgac gtggtttgaa gaaatttttg aagagtatca ttcaccattt
       61 cacaactaaa tcgaagactt tctgccgtaa tgaaaacacc tgaaacagct tggtttcagc
      121 tgtccggaaa ctttaagact taggttcaaa gtttaggtat ggaacttcga aggaggtcgc
      181 taccgtccgt cattacttag gaaagtctta aaaaatctat aaagtaaaaa gagcccgaca
      241 gctctttttg tttatactca atgaaaatca aaaagcaaac taggaaac
//
LOCUS       DAVBNN010000133          283 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVBNN010000133 DAVBNN010000000
VERSION     DAVBNN010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.133"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           63 t
ORIGIN      
        1 ctgaggtgta agtcctcggt gggcacctgt taccggtgaa cccaatagcg attcccaagc
       61 ctgactatcg tgaggtagcg gattaaaacg gtctggggat agaccgtttt aaatctgacg
      121 ctggaaataa gaatcgtcag aggaagggat agcgaactcg tggctctacg aacaggaacg
      181 tgatagtaag gcgtatatag cggataaggg ggcctcaaac tctaaagttc aaaaaggtag
      241 tcgtaaccta tatgcgtaaa tcacgagagc aactgaattt gtc
//
LOCUS       DAVBNN010000134          278 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVBNN010000134 DAVBNN010000000
VERSION     DAVBNN010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.134"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(1..154)
                     /locus_tag="VQ847_002073"
                     /pseudo
     CDS             complement(1..154)
                     /locus_tag="VQ847_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT           76 a           54 c           53 g           95 t
ORIGIN      
        1 catagccata aaacatttcg gattttaaaa tgccaaagaa ggactccatc ataccgttgt
       61 cttggctgtt tcccttgcgt gacatagatg cttgaattcc cttactctct aggaaccgat
      121 gataagaatc gtgttggtat tgccagcctt agtccttatc tgttttgtct agctgtttca
      181 agtgatagta gtaggtcgaa cgagctagtt taatggcttt tagaagaaga actaacgaaa
      241 actcagtcat taattcttga acaatttctg tctttctt
//
LOCUS       DAVBNN010000135          267 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVBNN010000135 DAVBNN010000000
VERSION     DAVBNN010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.135"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            complement(<1..>267)
                     /locus_tag="VQ847_002074"
     CDS             complement(<1..>267)
                     /locus_tag="VQ847_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3051332.1"
                     /translation="ELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGY
                     HPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLL"
BASE COUNT           91 a           49 c           60 g           67 t
ORIGIN      
        1 aagagaagtt gattaaaccg ttctaaaaca ggtgtgataa agctgtctgc ctcttcagaa
       61 caataacgat taccaggacg aagctgggca ttgaaacaat aacctgtctt cccctcgaaa
      121 gcataaagag gatgatagcc atgagcacga tagtgggcgt tataagcaac accttcttgc
      181 ttgccataag ttgtgaaatg ggtagaatcg atatctacaa tgagttggtt tagctggtga
      241 aactgtaaaa agaattcgac caattca
//
LOCUS       DAVBNN010000136          263 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVBNN010000136 DAVBNN010000000
VERSION     DAVBNN010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.136"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ847_002075"
     tRNA            1..73
                     /locus_tag="VQ847_002075"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ847_002076"
     tRNA            87..160
                     /locus_tag="VQ847_002076"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ847_002077"
     tRNA            171..260
                     /locus_tag="VQ847_002077"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
BASE COUNT           53 a           66 c           76 g           68 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct ttt
//
LOCUS       DAVBNN010000137          251 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 2645-09
            SAMEA1012604-rid20177673.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVBNN010000137 DAVBNN010000000
VERSION     DAVBNN010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012604
            Sequence Read Archive: ERR059375
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979965.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979965.1
            Genome Coverage       :: 573x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,034
            Genes (coding)                    :: 1,909
            CDSs (with protein)               :: 1,909
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 74 of 125
            Pseudo Genes (incomplete)         :: 48 of 125
            Pseudo Genes (internal stop)      :: 34 of 125
            Pseudo Genes (multiple problems)  :: 26 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012604-rid20177673.denovo.137"
                     /strain="NIG 2645-09"
                     /db_xref="taxon:1313"
     gene            <1..>251
                     /locus_tag="VQ847_002078"
     CDS             <1..>251
                     /locus_tag="VQ847_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3051333.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKG"
BASE COUNT           84 a           51 c           60 g           56 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag g
//
